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Overview
1.1
1.2

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP012938.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1 | arylpolyene | 5,252,133 | 5,299,737 | flexirubin | Other | 48%
Region 2 | RRE-containing | 6,029,320 | 6,049,670 |

NZ_CP012938.1 - Region 1 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 5,252,133 - 5,299,737 nt. (total: 47,605 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000839.1 |  | 0.30 | Other | flexirubin | Chitinophaga pinensis DSM 2588
BGC0001723.1 |  | 0.25 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0001197.1 |  | 0.23 | Polyketide | frankiamicin | Frankia sp. EAN1pec
BGC0000838.1 |  | 0.21 | Polyketide | flexirubin | Flavobacterium johnsoniae UW101
BGC0000248.1 |  | 0.20 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0000261.1 |  | 0.20 | Polyketide | R1128 | Streptomyces sp. R1128
BGC0000217.1 |  | 0.19 | Polyketide | daunorubicin | Streptomyces sp.
BGC0000218.1 |  | 0.19 | Polyketide | doxorubicin | Streptomyces peucetius
BGC0000237.1 |  | 0.19 | Polyketide | lactonamycin Z | Streptomyces sanglieri
BGC0000219.1 |  | 0.18 | Polyketide, Saccharide | elloramycin | Streptomyces olivaceus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000839.1 |  | 0.63 | Other | flexirubin | Chitinophaga pinensis DSM 2588
BGC0001723.1 |  | 0.58 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0001197.1 |  | 0.56 | Polyketide | frankiamicin | Frankia sp. EAN1pec
BGC0000838.1 |  | 0.54 | Polyketide | flexirubin | Flavobacterium johnsoniae UW101
BGC0000248.1 |  | 0.53 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0000261.1 |  | 0.52 | Polyketide | R1128 | Streptomyces sp. R1128
BGC0000217.1 |  | 0.51 | Polyketide | daunorubicin | Streptomyces sp.
BGC0000218.1 |  | 0.51 | Polyketide | doxorubicin | Streptomyces peucetius
BGC0000237.1 |  | 0.50 | Polyketide | lactonamycin Z | Streptomyces sanglieri
BGC0000219.1 |  | 0.50 | Polyketide, Saccharide | elloramycin | Streptomyces olivaceus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP012938.1 - Region 2 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 6,029,320 - 6,049,670 nt. (total: 20,351 nt) Show pHMM detection rules used
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001412.1 |  | 0.40 | Saccharide | polysaccharide C | Bacteroides fragilis
BGC0001588.1 |  | 0.17 | Saccharide | exopolysaccharides | Burkholderia pseudomallei 1026b
BGC0001120.1 |  | 0.17 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001589.1 |  | 0.16 | Saccharide | exopolysaccharides | Burkholderia cenocepacia J2315
BGC0001838.1 |  | 0.10 | NRP | WLIP | Pseudomonas putida
BGC0000190.1 |  | 0.06 | Polyketide | A-74528 | Streptomyces sp. SANK 61196
BGC0002025.1 |  | 0.06 | NRP | thaxteramide C | Jahnella sp. MSr9139
BGC0000224.1 |  | 0.05 | Polyketide | fredericamycin A | Streptomyces griseus
BGC0001093.1 |  | 0.05 | NRP, Polyketide | disorazol A | Sorangium cellulosum
BGC0001983.1 |  | 0.05 | Other | triacsins | Kitasatospora aureofaciens

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001412.1 |  | 0.72 | Saccharide | polysaccharide C | Bacteroides fragilis
BGC0001588.1 |  | 0.48 | Saccharide | exopolysaccharides | Burkholderia pseudomallei 1026b
BGC0001120.1 |  | 0.48 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001589.1 |  | 0.47 | Saccharide | exopolysaccharides | Burkholderia cenocepacia J2315
BGC0001838.1 |  | 0.36 | NRP | WLIP | Pseudomonas putida
BGC0000190.1 |  | 0.25 | Polyketide | A-74528 | Streptomyces sp. SANK 61196
BGC0002025.1 |  | 0.25 | NRP | thaxteramide C | Jahnella sp. MSr9139
BGC0000224.1 |  | 0.24 | Polyketide | fredericamycin A | Streptomyces griseus
BGC0001093.1 |  | 0.24 | NRP, Polyketide | disorazol A | Sorangium cellulosum
BGC0001983.1 |  | 0.23 | Other | triacsins | Kitasatospora aureofaciens

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names