LOCUS       NZ_CP010820.1          24225 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP010820.1 Lysinibacillus fusiformis strain RB-21 chromosome,
            complete genome.
ACCESSION   NZ_CP010820
VERSION     NZ_CP010820.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:41:29
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 4366419
            Orig. end    :: 4390644
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24225
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[4376419:4380644]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14225
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..24225
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..24225
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="7"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             769..1965
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1189:L-carnitine dehydratase/bile acid-inducible
                     (Score: 399.3; E-value: 2.6e-121)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4314"
                     /transl_table=11
                     /translation="MKQALEGLKVVDLSQVLAGPYCTMVLADMGAEVIKIEKYPNGDDT
                     RAMGPFVHEESHMYMMVNRNKKGVCLNLKTPEGLALFKELIQSVDVLVENYRPGITKKL
                     GIDYDTLKALNPGLIYCSISGYGQTGPYSQKGGYDIMAQGLSGLMHMTGEPQGRPVKVG
                     FAVNDIAAAQTALQSILMAYIYKLRSGEGQYIDVSLVESGLAWTVWEAAAYFGQGELPE
                     RTGTAHRVSAPYQGFKTQDDYILIGAGNQKLWEIFATKVVERPDWLDNPLFITNYSRAQ
                     HVKALEAEIESELEKHPATYWLELLDEHGVPSSPIYSYDQTLNDPHILERGMVLSYDHP
                     TAGPMRTLGFPAKFSGTPGQLTSAAPTLGQHNEEILQALNITDHEVQQLKKANVIRSK"
     PFAM_domain     781..1884
                     /aSDomain="CoA_transf_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02515.19"
                     /description="CoA-transferase family III"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4314_0158"
                     /evalue="2.10E-130"
                     /label="ctg1_4314"
                     /locus_tag="ctg1_4314"
                     /protein_end="372"
                     /protein_start="4"
                     /score="435.2"
                     /tool="antismash"
                     /translation="LEGLKVVDLSQVLAGPYCTMVLADMGAEVIKIEKYPNGDDTRAMG
                     PFVHEESHMYMMVNRNKKGVCLNLKTPEGLALFKELIQSVDVLVENYRPGITKKLGIDY
                     DTLKALNPGLIYCSISGYGQTGPYSQKGGYDIMAQGLSGLMHMTGEPQGRPVKVGFAVN
                     DIAAAQTALQSILMAYIYKLRSGEGQYIDVSLVESGLAWTVWEAAAYFGQGELPERTGT
                     AHRVSAPYQGFKTQDDYILIGAGNQKLWEIFATKVVERPDWLDNPLFITNYSRAQHVKA
                     LEAEIESELEKHPATYWLELLDEHGVPSSPIYSYDQTLNDPHILERGMVLSYDHPTAGP
                     MRTLGFPAKFSGTPGQLTSAAPTLGQHN"
     CDS             complement(2124..3323)
                     /NRPS_PKS="Domain: Aminotran_1_2 (44-385). E-value: 5e-68.
                     Score: 221.6. Matches aSDomain:
                     nrpspksdomains_ctg1_4315_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1109:8-amino-7-oxononanoate synthase (Score: 431.3;
                     E-value: 5.7e-131)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4315"
                     /transl_table=11
                     /translation="MIRLSKVLNAFLDENLQALHEQGLYNEIDPVEGANGPIIQVRGKN
                     LVNLSSNNYLGLATNEELKRIAKETIEKYGVGAGAVRTINGTLDLHVKLEEKLAEFKGT
                     EAAISYQSGFNCNMAAISAVMDKNDAILSDQLNHASIIDGCRLSKAKIIPFNHSDMDDL
                     RAKAKAAKESGLYNKVMVITDGVFSMDGDIAKLPEIVEIAKEFDLITYVDDAHGSGVTG
                     KGKGTVKHFGLEKEIDFQIGTLSKAIGVVGGYVAGKKNLIDWLKVRSRPFLFSTALPPG
                     DVAAITAAVQMLIDSTELHDKLWDNGNYLKAGLEKLGFNIGESETPITPCIIGDEKLTQ
                     EFSKRLFEEGVYAKSIVFPTVPKGTGRVRNMPTAAHTKEMLDDALGIYEKVGRELGVIQ
                     "
     aSDomain        complement(2130..3290)
                     /aSDomain="TIGR01825"
                     /aSTool="tigrfam"
                     /description="gly_Cac_T_rel: putative pyridoxal
                     phosphate-dependent acyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_4315_0030"
                     /evalue="7.30E-193"
                     /identifier="TIGR01825"
                     /label="ctg1_4315"
                     /locus_tag="ctg1_4315"
                     /protein_end="398"
                     /protein_start="11"
                     /score="638.4"
                     /tool="antismash"
                     /translation="LDENLQALHEQGLYNEIDPVEGANGPIIQVRGKNLVNLSSNNYLG
                     LATNEELKRIAKETIEKYGVGAGAVRTINGTLDLHVKLEEKLAEFKGTEAAISYQSGFN
                     CNMAAISAVMDKNDAILSDQLNHASIIDGCRLSKAKIIPFNHSDMDDLRAKAKAAKESG
                     LYNKVMVITDGVFSMDGDIAKLPEIVEIAKEFDLITYVDDAHGSGVTGKGKGTVKHFGL
                     EKEIDFQIGTLSKAIGVVGGYVAGKKNLIDWLKVRSRPFLFSTALPPGDVAAITAAVQM
                     LIDSTELHDKLWDNGNYLKAGLEKLGFNIGESETPITPCIIGDEKLTQEFSKRLFEEGV
                     YAKSIVFPTVPKGTGRVRNMPTAAHTKEMLDDALGIYEKVGRELGVI"
     aSDomain        complement(2169..3191)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_4315_Aminotran_1_2.1"
                     /evalue="5.00E-68"
                     /label="ctg1_4315_Aminotran_1_2.1"
                     /locus_tag="ctg1_4315"
                     /protein_end="385"
                     /protein_start="44"
                     /score="221.6"
                     /tool="antismash"
                     /translation="NLVNLSSNNYLGLATNEELKRIAKETIEKYGVGAGAVRTINGTLD
                     LHVKLEEKLAEFKGTEAAISYQSGFNCNMAAISAVMDKNDAILSDQLNHASIIDGCRLS
                     KAKIIPFNHSDMDDLRAKAKAAKESGLYNKVMVITDGVFSMDGDIAKLPEIVEIAKEFD
                     LITYVDDAHGSGVTGKGKGTVKHFGLEKEIDFQIGTLSKAIGVVGGYVAGKKNLIDWLK
                     VRSRPFLFSTALPPGDVAAITAAVQMLIDSTELHDKLWDNGNYLKAGLEKLGFNIGESE
                     TPITPCIIGDEKLTQEFSKRLFEEGVYAKSIVFPTVPKGTGRVRNMPTAAHTKEMLDDA
                     L"
     PFAM_domain     complement(2169..3191)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00155.23"
                     /description="Aminotransferase class I and II"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4315_0159"
                     /evalue="1.80E-65"
                     /label="ctg1_4315"
                     /locus_tag="ctg1_4315"
                     /protein_end="385"
                     /protein_start="44"
                     /score="221.6"
                     /tool="antismash"
                     /translation="NLVNLSSNNYLGLATNEELKRIAKETIEKYGVGAGAVRTINGTLD
                     LHVKLEEKLAEFKGTEAAISYQSGFNCNMAAISAVMDKNDAILSDQLNHASIIDGCRLS
                     KAKIIPFNHSDMDDLRAKAKAAKESGLYNKVMVITDGVFSMDGDIAKLPEIVEIAKEFD
                     LITYVDDAHGSGVTGKGKGTVKHFGLEKEIDFQIGTLSKAIGVVGGYVAGKKNLIDWLK
                     VRSRPFLFSTALPPGDVAAITAAVQMLIDSTELHDKLWDNGNYLKAGLEKLGFNIGESE
                     TPITPCIIGDEKLTQEFSKRLFEEGVYAKSIVFPTVPKGTGRVRNMPTAAHTKEMLDDA
                     L"
     CDS             complement(3382..4458)
                     /locus_tag="ctg1_4316"
                     /transl_table=11
                     /translation="LNGNVTYYFGHALTGQGVKHLYKEMMEEAELVYFLQGASTSKGSE
                     LLKELGYFYVKQGFAVEWFKHALLEEVVEAVYVKGCNRLYVWASEWDIEPTLLGTKHRV
                     MSFYDCLEDAQLEKIGEQLANAVQERTAWRDKCIAKLNHAIKLHDDWEVVTQSCMNWQA
                     LNEQVENLKLEVFQSIVLNKTGERTHRLLGTLTPRGAENTVESITKNISTRLMIKGKPG
                     TGKSSLMKGLADEANARGLDAQIVWCGLDAGSVDMVIIPELNFCIFDSTEPHIFDPQDG
                     RLGDKIFDIGQHCALTEEAELAIAEVRARYKEAMQDAMGYSKRYAEAEYTVRRLLDHCL
                     SASLWREKTASLFERLTK"
     CDS             complement(4560..5195)
                     /locus_tag="ctg1_4317"
                     /transl_table=11
                     /translation="MRKIMGWRWTFFIGGLIVMSLGITMSIKGKIVGTSPWDVLHVGLF
                     QNFGLTIGTWSILTGLFIVASTSIVLQTWPKIGTWLNMLLIGSFIDVFNWLLPSTDVYG
                     LQITYFIIGLFVLSFGCGMYIAPNMGAGPRDTLMMILVEKFGGSIKTARMGIEVLVTIV
                     GWLLGGPVGVGTVLIALTSGYIVQYSLPYCRKVLMKCIGHIEDMKPFY"
     CDS             complement(5327..5818)
                     /locus_tag="ctg1_4318"
                     /transl_table=11
                     /translation="MAKAKHAKTNAIRLLEQQKIQFDVIEYEIGDGQVDGVSVAEKIGQ
                     PVARVFKTLVAKASAQKLFVFVIPVAGELDLKAAAKVVGEKKIDMLPVKDLLSYTGYVR
                     GGCSPVGMKKLYPTVIDETAQEQGCIIVSAGKIGMQIHVQLNDLKNITKAQLAPITTTH
                     "
     aSDomain        complement(5339..5794)
                     /aSDomain="TIGR00011"
                     /aSTool="tigrfam"
                     /description="YbaK_EbsC: Cys-tRNA(Pro) deacylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_4318_0031"
                     /evalue="1.30E-56"
                     /identifier="TIGR00011"
                     /label="ctg1_4318"
                     /locus_tag="ctg1_4318"
                     /protein_end="160"
                     /protein_start="8"
                     /score="188.6"
                     /tool="antismash"
                     /translation="TNAIRLLEQQKIQFDVIEYEIGDGQVDGVSVAEKIGQPVARVFKT
                     LVAKASAQKLFVFVIPVAGELDLKAAAKVVGEKKIDMLPVKDLLSYTGYVRGGCSPVGM
                     KKLYPTVIDETAQEQGCIIVSAGKIGMQIHVQLNDLKNITKAQLAPIT"
     PFAM_domain     complement(5369..5704)
                     /aSDomain="tRNA_edit"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04073.17"
                     /description="Aminoacyl-tRNA editing domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4318_0160"
                     /evalue="1.00E-20"
                     /label="ctg1_4318"
                     /locus_tag="ctg1_4318"
                     /protein_end="150"
                     /protein_start="38"
                     /score="74.1"
                     /tool="antismash"
                     /translation="VAEKIGQPVARVFKTLVAKASAQKLFVFVIPVAGELDLKAAAKVV
                     GEKKIDMLPVKDLLSYTGYVRGGCSPVGMKKLYPTVIDETAQEQGCIIVSAGKIGMQIH
                     VQLNDLKN"
     CDS             complement(5843..6568)
                     /locus_tag="ctg1_4319"
                     /transl_table=11
                     /translation="MKIYNSMEQERLSSPFNRKKFLQRKEAGDAYRKNAMYFQPKKNPL
                     LLELENLLLGRTDQDLYEQQQEDAEVVTPQQQAIMEDLQQTSKNVHAHEQAYKWASGHH
                     DGSPVVNNPDMNDTLQVLEQVRNAALSPSKPSAQDIRLAENVDAQIQHILHEANSTVEA
                     IDEQNQPFDNEVTTVKVPERFSKELKLDPFADTIFGKSHDAAFKLRAFKQATEKYAAHV
                     QMTKNGYHPGNDSMFSLIA"
     CDS             complement(6894..7493)
                     /locus_tag="ctg1_4320"
                     /transl_table=11
                     /translation="MGRNKGKRVFSMSKNNITDVQGNAKLPLPYRDVIDTYYLPIKIVG
                     WMLFSIYSCLAFYKLVIDRLVNVVVVLWEGDYSVGDLGLFDYSSWRLTTNFIPFETIFR
                     YINYSQYFNWDTIIINLLGNLLIFTPMGFLLPLLSKKFRKAGVILCLGFFASLSVETIQ
                     FIFTVGSADIDDLILNTIGAWLGYLAYKCLLITPKK"
     PFAM_domain     complement(6918..7232)
                     /aSDomain="VanZ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04892.14"
                     /description="VanZ like family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4320_0161"
                     /evalue="3.00E-26"
                     /label="ctg1_4320"
                     /locus_tag="ctg1_4320"
                     /protein_end="192"
                     /protein_start="87"
                     /score="92.6"
                     /tool="antismash"
                     /translation="SSWRLTTNFIPFETIFRYINYSQYFNWDTIIINLLGNLLIFTPMG
                     FLLPLLSKKFRKAGVILCLGFFASLSVETIQFIFTVGSADIDDLILNTIGAWLGYLAYK
                     C"
     CDS             complement(7591..9129)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase,
                     (Score: 516.5; E-value: 1.4e-156)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4321"
                     /transl_table=11
                     /translation="MSNISTENTPPTMKDKILSGGLPKYHDKNAQQGKLFVRERLELLL
                     DDGLQSEDGLYANCLAGDLPADGVVTGIGKIHGRTVCVLANDSTIKAGSWGKRTVEKMI
                     RIQETAEKLNCPLLYLVDSAGARITDQLEMFPGRRGAGRIFYNQVKLSGKVPQICLLFG
                     PSAAGGAYIPAFCDIVVMVEGNASMYLGSPRMAEMVIGEKVDLETMGGAKMHCSVSGCG
                     DVLAKTEQEAIAYARKYLGYFPNNYAERSKVEAPKPPATFDKSIEELIPQNQNVPFDMY
                     KLIERIIDEDSFCEVKKLFAPELITGLARIKGQSVGIIANQPRVKGGVLFHDSADKAAK
                     FISLCDAFNIPLLFLADVPGFMIGTQVEKAGIIRHGAKMIFAMSEATVPKLTVIVRKAY
                     GAGLYAMAGPAFEPDCCIALSNAQIAVMGPEAAVNAVYANKIAELPKEEQASFIAEKRK
                     EYQEEIDVYRLASELIIDDVIEPNDLRKVLENRLELYMSKYLLFSQRKHGVNPV"
     PFAM_domain     complement(7603..9045)
                     /aSDomain="Carboxyl_trans"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01039.24"
                     /description="Carboxyl transferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4321_0162"
                     /evalue="1.10E-159"
                     /label="ctg1_4321"
                     /locus_tag="ctg1_4321"
                     /protein_end="509"
                     /protein_start="28"
                     /score="532.3"
                     /tool="antismash"
                     /translation="NAQQGKLFVRERLELLLDDGLQSEDGLYANCLAGDLPADGVVTGI
                     GKIHGRTVCVLANDSTIKAGSWGKRTVEKMIRIQETAEKLNCPLLYLVDSAGARITDQL
                     EMFPGRRGAGRIFYNQVKLSGKVPQICLLFGPSAAGGAYIPAFCDIVVMVEGNASMYLG
                     SPRMAEMVIGEKVDLETMGGAKMHCSVSGCGDVLAKTEQEAIAYARKYLGYFPNNYAER
                     SKVEAPKPPATFDKSIEELIPQNQNVPFDMYKLIERIIDEDSFCEVKKLFAPELITGLA
                     RIKGQSVGIIANQPRVKGGVLFHDSADKAAKFISLCDAFNIPLLFLADVPGFMIGTQVE
                     KAGIIRHGAKMIFAMSEATVPKLTVIVRKAYGAGLYAMAGPAFEPDCCIALSNAQIAVM
                     GPEAAVNAVYANKIAELPKEEQASFIAEKRKEYQEEIDVYRLASELIIDDVIEPNDLRK
                     VLENRLELYMSKYLLFSQRKHGV"
     CDS             complement(9222..10004)
                     /NRPS_PKS="Domain: ECH (9-252). E-value: 7.8e-70. Score:
                     226.8. Matches aSDomain: nrpspksdomains_ctg1_4322_ECH.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 250; E-value:
                     3.3e-76)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4322"
                     /transl_table=11
                     /translation="MTQLVRFELLEGSIGLITLLRPEAANAMSVQLLRELSDTLDQING
                     DPTVRVVLLTGAGEKAFCAGADLKERKGMSDRQVKQIVQLIGATVAKVETLAQPVIAVL
                     NGVAFGGGLELALACDLRVAAAHVKLGLTETSLGIIPGAGGTQRLPRLIGLGKAKELIY
                     TARRLNAEEAKNYGIVEYVHETHEVMERAQQLALEMAKNAPLSLVQAKVAMNQGVEVDL
                     ATGLKIESLAYSALIPTEDRLEGLLAFQEKRAPHYSGK"
     PFAM_domain     complement(9228..9971)
                     /aSDomain="ECH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00378.22"
                     /description="Enoyl-CoA hydratase/isomerase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4322_0163"
                     /evalue="1.90E-67"
                     /label="ctg1_4322"
                     /locus_tag="ctg1_4322"
                     /protein_end="259"
                     /protein_start="11"
                     /score="227.3"
                     /tool="antismash"
                     /translation="GSIGLITLLRPEAANAMSVQLLRELSDTLDQINGDPTVRVVLLTG
                     AGEKAFCAGADLKERKGMSDRQVKQIVQLIGATVAKVETLAQPVIAVLNGVAFGGGLEL
                     ALACDLRVAAAHVKLGLTETSLGIIPGAGGTQRLPRLIGLGKAKELIYTARRLNAEEAK
                     NYGIVEYVHETHEVMERAQQLALEMAKNAPLSLVQAKVAMNQGVEVDLATGLKIESLAY
                     SALIPTEDRLEGLLAFQEKRAPHYSG"
     aSDomain        complement(9249..9977)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_4322_ECH.1"
                     /evalue="7.80E-70"
                     /label="ctg1_4322_ECH.1"
                     /locus_tag="ctg1_4322"
                     /protein_end="252"
                     /protein_start="9"
                     /score="226.8"
                     /tool="antismash"
                     /translation="LEGSIGLITLLRPEAANAMSVQLLRELSDTLDQINGDPTVRVVLL
                     TGAGEKAFCAGADLKERKGMSDRQVKQIVQLIGATVAKVETLAQPVIAVLNGVAFGGGL
                     ELALACDLRVAAAHVKLGLTETSLGIIPGAGGTQRLPRLIGLGKAKELIYTARRLNAEE
                     AKNYGIVEYVHETHEVMERAQQLALEMAKNAPLSLVQAKVAMNQGVEVDLATGLKIESL
                     AYSALIPTEDRLEGLLAFQEK"
     CDS             complement(10001..10918)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 240.2;
                     E-value: 7.5e-73)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4323"
                     /sec_met_domain="HMGL-like (E-value: 4.1e-53, bitscore:
                     178.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLPKHVVMKEVGPRDGLQNEKTHITTADKIQLVNLLSQTGLNYI
                     EVTSFVHPKWIPQLADAVEVLQAIKRNKDITYAALVPNMRGLERALQAGVDEVSIFMSA
                     SESHNQSNINKTIDETFPILEEVVLGAKASKKKVRGYISTVLGCPYEGYIHPDKVLRVT
                     DKLLEMGVTEISLGDTIGVGVPTQVELLLEELLKRYSANNFAMHFHDTRGTALANIMKS
                     LEMGVTKFDSALGGLGGCPYAKGASGNVATEDLLYLFDEMGIQTGVDRQKIVEAALFIE
                     QKLGKAVASKQMAIVRNERSANPL"
     PFAM_domain     complement(10085..10894)
                     /aSDomain="HMGL-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00682.21"
                     /description="HMGL-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4323_0164"
                     /evalue="9.60E-53"
                     /label="ctg1_4323"
                     /locus_tag="ctg1_4323"
                     /protein_end="278"
                     /protein_start="8"
                     /score="179.5"
                     /tool="antismash"
                     /translation="MKEVGPRDGLQNEKTHITTADKIQLVNLLSQTGLNYIEVTSFVHP
                     KWIPQLADAVEVLQAIKRNKDITYAALVPNMRGLERALQAGVDEVSIFMSASESHNQSN
                     INKTIDETFPILEEVVLGAKASKKKVRGYISTVLGCPYEGYIHPDKVLRVTDKLLEMGV
                     TEISLGDTIGVGVPTQVELLLEELLKRYSANNFAMHFHDTRGTALANIMKSLEMGVTKF
                     DSALGGLGGCPYAKGASGNVATEDLLYLFDEMGIQTGVDRQKIVEAAL"
     CDS             complement(10933..11145)
                     /locus_tag="ctg1_4324"
                     /transl_table=11
                     /translation="MATVKASMAGTVWKIVVAEGEKVTAGQDVAILESMKMEIPIAAEE
                     DGVVTKIIANEGDFINVDDDILEIE"
     PFAM_domain     complement(10939..11139)
                     /aSDomain="Biotin_lipoyl"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00364.24"
                     /description="Biotin-requiring enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4324_0165"
                     /evalue="5.70E-18"
                     /label="ctg1_4324"
                     /locus_tag="ctg1_4324"
                     /protein_end="69"
                     /protein_start="2"
                     /score="64.6"
                     /tool="antismash"
                     /translation="TVKASMAGTVWKIVVAEGEKVTAGQDVAILESMKMEIPIAAEEDG
                     VVTKIIANEGDFINVDDDILEI"
     CDS             complement(11217..12575)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090:acetyl-CoA carboxylase biotin carboxylase (Score:
                     643.2; E-value: 9.1e-195)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4325"
                     /sec_met_domain="RimK (E-value: 1.2e-05, bitscore: 23.2,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 4.4e-09, bitscore:
                     34.3, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFNKVLIANRGEIARRIIRTCRRLNIHTVAIYSEADAESLHVKDA
                     DEAYCVGKPPVAQSYLNIERILEIALENGVEAVHPGYGLLSEHAEFAKRCEEEGLIFIG
                     PSADVIASMGSKLEARKTMKAAGVPIVEGVETPVKDAEEATEIAERLGYPIMLKASAGG
                     GGIGMQLVENAEELAKAFEGNQKRAQSFFGDGTMYMERFIASPHHVEVQIIADHQGNVV
                     PLFERECSIQRRNQKVVEEAPSPFISQETRDKMLEASVKAAKHIGYINAGTIEYLVDED
                     QNFYFLEMNTRLQVEHPVTEEITKLDLVEEQLKIAAQQPLSFTKESITKQGHAIEVRIY
                     AENPSTFFPSPGTITALELPTGEGVRHECGVEAGSAVTPFYDPMISKLVVWGETRDIAC
                     ERLIQALKAYKVEGIQTNIPMLLKTVTHEQFLKGYTTTKFVEQFYLPQLAESK"
     PFAM_domain     complement(11250..11570)
                     /aSDomain="Biotin_carb_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02785.21"
                     /description="Biotin carboxylase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4325_0168"
                     /evalue="1.50E-35"
                     /label="ctg1_4325"
                     /locus_tag="ctg1_4325"
                     /protein_end="442"
                     /protein_start="335"
                     /score="121.6"
                     /tool="antismash"
                     /translation="EVRIYAENPSTFFPSPGTITALELPTGEGVRHECGVEAGSAVTPF
                     YDPMISKLVVWGETRDIACERLIQALKAYKVEGIQTNIPMLLKTVTHEQFLKGYTTTKF
                     VEQ"
     PFAM_domain     complement(11610..12230)
                     /aSDomain="CPSase_L_D2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02786.19"
                     /description="Carbamoyl-phosphate synthase L chain, ATP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4325_0167"
                     /evalue="2.10E-77"
                     /label="ctg1_4325"
                     /locus_tag="ctg1_4325"
                     /protein_end="322"
                     /protein_start="115"
                     /score="259.5"
                     /tool="antismash"
                     /translation="KLEARKTMKAAGVPIVEGVETPVKDAEEATEIAERLGYPIMLKAS
                     AGGGGIGMQLVENAEELAKAFEGNQKRAQSFFGDGTMYMERFIASPHHVEVQIIADHQG
                     NVVPLFERECSIQRRNQKVVEEAPSPFISQETRDKMLEASVKAAKHIGYINAGTIEYLV
                     DEDQNFYFLEMNTRLQVEHPVTEEITKLDLVEEQLKIAAQQPLS"
     PFAM_domain     complement(12246..12575)
                     /aSDomain="Biotin_carb_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00289.24"
                     /description="Biotin carboxylase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4325_0166"
                     /evalue="3.50E-46"
                     /label="ctg1_4325"
                     /locus_tag="ctg1_4325"
                     /protein_end="110"
                     /protein_start="0"
                     /score="156.4"
                     /tool="antismash"
                     /translation="MFNKVLIANRGEIARRIIRTCRRLNIHTVAIYSEADAESLHVKDA
                     DEAYCVGKPPVAQSYLNIERILEIALENGVEAVHPGYGLLSEHAEFAKRCEEEGLIFIG
                     PSADVI"
     CDS             complement(12591..14225)
                     /NRPS_PKS="Domain: AMP-binding (13-445). E-value: 1.3e-102.
                     Score: 335.2. Matches aSDomain:
                     nrpspksdomains_ctg1_4326_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     419.6; E-value: 2.3e-127)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4326"
                     /sec_met_domain="AMP-binding (E-value: 3.1e-109, bitscore:
                     363.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELVYQTIGQLLDEQSKKYPQNEALVYADRNLRMTYEQLNCQAR
                     LVARGLMALGIEKGDHIAVWTTNVPEWVQLQFGTGKMGAPIVTVNTNYRASELEYLLKQ
                     SDAKTIFLIENYRDHSFIHTLQELCPELEHCAPGNLQSKRLPLLKNVILIGETKYPGVL
                     NWSDVVAAADQVTEEQLEQREQSLHYDDVINIQYTSGTTGFPKGVMLTHFNLVNNAVNI
                     AECMRLTAEDRLCIPVPFFHCFGCVIGTLAITTSGGTMVPVQEFSPEEVLRTVQQEKCT
                     ALHGVPTMFISELNLPNFESFNLSTLRTGVMAGSNCPIEVMKAVIEKMGMTDITICYGQ
                     TESSPVITQTRTDDPLALKVETVGRALPNLEAKIVVPGTNEEAPTNEQGELCTRGYHVM
                     KGYYKNQEETDLAIDQDGWLHTGDLATMDEAGYVRVTGRLKDMIIRGGENLYPREMEEF
                     LYTHPKISDVQVAGVPDPVYGEEAAAWIILREGEQATEEEIREYCRDKISRHKIPKHIF
                     FIDHYPMTASGKVQKYKLREDFVMTVR"
     PFAM_domain     complement(12639..12866)
                     /aSDomain="AMP-binding_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13193.8"
                     /description="AMP-binding enzyme C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4326_0170"
                     /evalue="1.60E-17"
                     /label="ctg1_4326"
                     /locus_tag="ctg1_4326"
                     /protein_end="529"
                     /protein_start="453"
                     /score="64.3"
                     /tool="antismash"
                     /translation="EMEEFLYTHPKISDVQVAGVPDPVYGEEAAAWIILREGEQATEEE
                     IREYCRDKISRHKIPKHIFFIDHYPMTASGK"
     aSDomain        complement(12891..14186)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_4326_AMP-binding.1"
                     /evalue="1.30E-102"
                     /label="ctg1_4326_AMP-binding.1"
                     /locus_tag="ctg1_4326"
                     /protein_end="445"
                     /protein_start="13"
                     /score="335.2"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="DEQSKKYPQNEALVYADRNLRMTYEQLNCQARLVARGLMALGIEK
                     GDHIAVWTTNVPEWVQLQFGTGKMGAPIVTVNTNYRASELEYLLKQSDAKTIFLIENYR
                     DHSFIHTLQELCPELEHCAPGNLQSKRLPLLKNVILIGETKYPGVLNWSDVVAAADQVT
                     EEQLEQREQSLHYDDVINIQYTSGTTGFPKGVMLTHFNLVNNAVNIAECMRLTAEDRLC
                     IPVPFFHCFGCVIGTLAITTSGGTMVPVQEFSPEEVLRTVQQEKCTALHGVPTMFISEL
                     NLPNFESFNLSTLRTGVMAGSNCPIEVMKAVIEKMGMTDITICYGQTESSPVITQTRTD
                     DPLALKVETVGRALPNLEAKIVVPGTNEEAPTNEQGELCTRGYHVMKGYYKNQEETDLA
                     IDQDGWLHTGDLATMDEAGYVRVTGRLKDMIIR"
     PFAM_domain     complement(12891..14186)
                     /aSDomain="AMP-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00501.30"
                     /description="AMP-binding enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4326_0169"
                     /evalue="2.80E-106"
                     /label="ctg1_4326"
                     /locus_tag="ctg1_4326"
                     /protein_end="445"
                     /protein_start="13"
                     /score="355.7"
                     /tool="antismash"
                     /translation="DEQSKKYPQNEALVYADRNLRMTYEQLNCQARLVARGLMALGIEK
                     GDHIAVWTTNVPEWVQLQFGTGKMGAPIVTVNTNYRASELEYLLKQSDAKTIFLIENYR
                     DHSFIHTLQELCPELEHCAPGNLQSKRLPLLKNVILIGETKYPGVLNWSDVVAAADQVT
                     EEQLEQREQSLHYDDVINIQYTSGTTGFPKGVMLTHFNLVNNAVNIAECMRLTAEDRLC
                     IPVPFFHCFGCVIGTLAITTSGGTMVPVQEFSPEEVLRTVQQEKCTALHGVPTMFISEL
                     NLPNFESFNLSTLRTGVMAGSNCPIEVMKAVIEKMGMTDITICYGQTESSPVITQTRTD
                     DPLALKVETVGRALPNLEAKIVVPGTNEEAPTNEQGELCTRGYHVMKGYYKNQEETDLA
                     IDQDGWLHTGDLATMDEAGYVRVTGRLKDMIIR"
     CDS_motif       complement(12996..13070)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_4326_0002"
                     /evalue="5.70E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg1_4326"
                     /protein_end="410"
                     /protein_start="385"
                     /score="12.4"
                     /tool="antismash"
                     /translation="NEQGELCTRGYHVMKGYYKNQEETD"
     CDS_motif       complement(13590..13643)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_4326_0001"
                     /evalue="1.30E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg1_4326"
                     /protein_end="212"
                     /protein_start="194"
                     /score="24.0"
                     /tool="antismash"
                     /translation="IQYTSGTTGFPKGVMLTH"
     CDS             complement(14373..15515)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 442.5; E-value:
                     2.1e-134)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4327"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.3e-39, bitscore:
                     132.7, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 2.9e-27, bitscore:
                     92.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.3e-50, bitscore:
                     169.6, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFELTKEQVMIRDMVRDFAEKEIKPYAREVDETSTMRIESFKKM
                     AELGLLGIPFPEEYGGSGGDTVSYALAVEEIGRACGGTGLSYAAAVSLGASPIYNFGTE
                     EQKQEFLVPLAKGETLGSFGLTEPNAGSDAGGTRTTAVIDGDDYVINGEKCWITNAGYA
                     RQIIVTAVTGKREDGKKIISSIIVPTNTPGVTINCNYDKMGVRGSNTCEIVLQNVRVPR
                     SNLLGDEKRGFSQFLNTLDGGRISIAALSVGIAQAAYEKALKFAKEREQFGAPISKLQA
                     IQFKLADMAMEIELARTLVHKAAWLKDQKKPFGKEAAMAKLFASEMGFRTCNQAIQIHG
                     GSGYMKEYDVERHLRDIKLMEIGEGTSEIQRLVISRLIGC"
     PFAM_domain     complement(14388..14825)
                     /aSDomain="Acyl-CoA_dh_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00441.26"
                     /description="Acyl-CoA dehydrogenase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4327_0173"
                     /evalue="5.30E-50"
                     /label="ctg1_4327"
                     /locus_tag="ctg1_4327"
                     /protein_end="376"
                     /protein_start="230"
                     /score="169.6"
                     /tool="antismash"
                     /translation="RGFSQFLNTLDGGRISIAALSVGIAQAAYEKALKFAKEREQFGAP
                     ISKLQAIQFKLADMAMEIELARTLVHKAAWLKDQKKPFGKEAAMAKLFASEMGFRTCNQ
                     AIQIHGGSGYMKEYDVERHLRDIKLMEIGEGTSEIQRLVISR"
     PFAM_domain     complement(14862..15152)
                     /aSDomain="Acyl-CoA_dh_M"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02770.21"
                     /description="Acyl-CoA dehydrogenase, middle domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4327_0172"
                     /evalue="2.60E-27"
                     /label="ctg1_4327"
                     /locus_tag="ctg1_4327"
                     /protein_end="218"
                     /protein_start="121"
                     /score="94.9"
                     /tool="antismash"
                     /translation="SFGLTEPNAGSDAGGTRTTAVIDGDDYVINGEKCWITNAGYARQI
                     IVTAVTGKREDGKKIISSIIVPTNTPGVTINCNYDKMGVRGSNTCEIVLQNV"
     PFAM_domain     complement(15162..15500)
                     /aSDomain="Acyl-CoA_dh_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02771.18"
                     /description="Acyl-CoA dehydrogenase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4327_0171"
                     /evalue="1.40E-39"
                     /label="ctg1_4327"
                     /locus_tag="ctg1_4327"
                     /protein_end="118"
                     /protein_start="5"
                     /score="135.3"
                     /tool="antismash"
                     /translation="TKEQVMIRDMVRDFAEKEIKPYAREVDETSTMRIESFKKMAELGL
                     LGIPFPEEYGGSGGDTVSYALAVEEIGRACGGTGLSYAAAVSLGASPIYNFGTEEQKQE
                     FLVPLAKGE"
     CDS             complement(15636..16253)
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 108.1; E-value: 1.2e-32)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_4328"
                     /transl_table=11
                     /translation="MVKKTLKQRIVDASVELFQQDGYHNVTVDRIVEYIGASKGGFYHN
                     FKSKDELLYEIHDVFISYVIQQSQDAYDKYDTPIPRLCAMLQTLTQVFDMYQAHITIFY
                     EESRSLSEEYSEIIHKKRDHYRDILQKVIAEGQETKVFRTELPCTIVTMAIVGMINWTY
                     KWFKQSGPLTMEQITDVFTDMVLRAIVTEQAMDEAKQFMIKG"
     PFAM_domain     complement(15690..16028)
                     /aSDomain="TetR_C_24"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17932.3"
                     /description="Tetracyclin repressor-like, C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4328_0175"
                     /evalue="4.00E-32"
                     /label="ctg1_4328"
                     /locus_tag="ctg1_4328"
                     /protein_end="188"
                     /protein_start="75"
                     /score="110.9"
                     /tool="antismash"
                     /translation="DTPIPRLCAMLQTLTQVFDMYQAHITIFYEESRSLSEEYSEIIHK
                     KRDHYRDILQKVIAEGQETKVFRTELPCTIVTMAIVGMINWTYKWFKQSGPLTMEQITD
                     VFTDMVLRA"
     PFAM_domain     complement(16089..16226)
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00440.25"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4328_0174"
                     /evalue="2.10E-16"
                     /label="ctg1_4328"
                     /locus_tag="ctg1_4328"
                     /protein_end="55"
                     /protein_start="9"
                     /score="59.5"
                     /tool="antismash"
                     /translation="IVDASVELFQQDGYHNVTVDRIVEYIGASKGGFYHNFKSKDELLY
                     E"
ORIGIN
        1 actcgaagat gttgccgaag ctgccccttc agcaacaaaa tggttccaat tgtattggtc
       61 tacaaatgag gaaattgcat ttagtatggc cgcacgagca gagtcagcag gctttgaagc
      121 aattgtttta acagtcgata cagtaatgct tggatggcga gaagaagatg tacgcaatca
      181 attttcacca ttaaagctag gctacgcaaa aggaaattac ataaatgatc ctgtctttat
      241 ggcttctttg cctaatgatt catttgaatc gtatgtacaa ggcgtcttgc aaaatgtctt
      301 ccaccctaca ctcaattggg agcatgttcg tgaattaaaa cgacgtacaa atcttcctat
      361 attattaaag ggaattttac atcctgaaga tgcaaagcta gcccttgaaa atgggattga
      421 cgggattatc gtatcgaacc atggcggccg acaattagat ggtgttattg gttcacttga
      481 tgccctcccc gccatcgtga gtgctgtcaa tggacaaatc cctataattt tagatagtgg
      541 tgtatatcgc gggatggatg ccttaaaagc acttgcttta ggagctgatg ccgtagcaat
      601 tgggcgtccc ttcgtctatg gcttagccct tgaaggacaa caaggtgccg aaaaagtgat
      661 gacaaatatc tatgatgaat taaaggtttc tattgcatta gcaggcacaa cctccatcga
      721 agggttacgt acgattacat tagtcaaaaa tgatgggact gaggttaaat gaaacaggca
      781 ttagagggat taaaagttgt tgatttatca caagtattag cgggacctta ttgcacaatg
      841 gtcttagctg atatgggcgc agaagttatt aaaattgaga aatatccaaa tggagacgac
      901 acccgagcaa tgggcccgtt cgttcatgaa gaaagtcata tgtatatgat ggttaatcgc
      961 aataaaaaag gtgtatgtct aaatttaaaa acgccagagg gcttggcttt attcaaagag
     1021 cttatccaat ctgttgatgt acttgtggaa aactatcgac caggtattac gaaaaagcta
     1081 gggattgatt atgatacttt aaaagccctt aatccaggac tcatttactg ctctatttct
     1141 ggctatggac aaacgggtcc ttatagccaa aaaggtggct atgatattat ggcacaaggt
     1201 ctaagtggct taatgcatat gactggagaa cctcagggtc gacctgtaaa agttggcttt
     1261 gctgtcaatg atattgccgc tgcccaaacg gccttacaat ctattttaat ggcctatatt
     1321 tataagctgc gaagtggtga ggggcaatat atcgatgttt ctttagtaga gtctgggctt
     1381 gcttggactg tttgggaggc cgctgcctac tttggtcaag gcgaattacc cgagcgaaca
     1441 ggaactgccc atcgagtttc cgcaccctat caaggcttta aaacacagga tgactatatt
     1501 ttaataggtg ctggcaatca aaagttatgg gaaatttttg cgacaaaggt tgtcgaacga
     1561 cctgattggt tagacaatcc cctctttatt actaactatt cacgtgctca gcatgtaaag
     1621 gcgttagagg cagaaattga aagtgaatta gagaaacatc cagcaaccta ctggctggag
     1681 cttttagatg aacacggcgt accatccagc cctatctatt cctatgacca aaccttaaat
     1741 gatccccata ttttagagcg tggtatggtc ttgtcctatg accatccaac tgctggtccc
     1801 atgagaacac taggtttccc agcaaaattc tcaggaacgc cgggtcaatt aacaagtgca
     1861 gcgccaactt taggacagca taatgaagaa attttgcagg ccttaaacat cactgatcat
     1921 gaagttcagc agctaaaaaa agcaaatgta atacgctcaa aataagaagc cctttatttt
     1981 gacaagctat cgattacttt ttggcgggct gtccgtcact ttcctcaggc tatcagtcac
     2041 ttcatagaat ttgattggaa tgaagcgccc gttttcattg taatcgaaaa ggctacctcc
     2101 acaacgaagg tagccttttc gtattattga attacaccta attcacgacc aactttctcg
     2161 taaataccta acgcatcatc aagcatttct tttgtatgag ctgctgttgg catattacgc
     2221 acgcgacctg tacctttagg aacggttggg aatacgattg attttgcata aacgccttct
     2281 tcaaataagc gttttgaaaa ttcttgtgtc agcttttcat ctccaataat acatggagta
     2341 attggtgttt ctgattcacc aatattaaag ccaagcttct ctagtcccgc ttttaaatag
     2401 ttaccattat cccacagctt atcgtgaagc tctgtagaat caattagcat ttgtacagca
     2461 gctgtaatgg cggccacatc acctggtggt agagctgttg agaacaagaa tggacgtgag
     2521 cgaactttta accaatcaat taagttcttc ttcccagcta catagccacc cacgacacca
     2581 attgctttgg atagtgtacc aatttggaag tcaatctctt tttctagtcc gaagtgcttc
     2641 acagttcctt tacctttacc tgttacaccc gaaccatgtg catcatcaac ataagtaatt
     2701 aaatcaaact ctttggcaat ttctacaatt tctggcaatt tggcgatatc gccatccatt
     2761 gagaatacac catccgtaat aaccatcact ttattgtata atccagattc ttttgccgct
     2821 tttgccttag cacgtaaatc atccatatct gagtgattaa acggaatgat tttcgccttt
     2881 gataaacgac aaccgtcaat aatagaggca tggtttaatt gatccgaaag aattgcatcg
     2941 tttttatcca taacagcaga aatagctgcc atattacaat taaagccaga ttgataagaa
     3001 atagctgctt ctgttccttt aaattcagca agcttttcct ctaatttaac gtgtaagtca
     3061 agcgtcccgt taatagtacg aacagcacct gctccaacac cgtatttttc aatcgtttct
     3121 ttggcaatac gctttaattc ttcattagtt gctaggccta gataattgtt agaagataag
     3181 ttaacaagat ttttgccacg tacctgaata atcgggccat ttgcaccctc tactggatca
     3241 atttcattgt ataagccttg ttcatgtaag gcttgtaggt tttcgtctaa aaatgcattc
     3301 aatacttttg acaagcgtat catcctttcc taggaaaaca gttctagctc ctagtttagc
     3361 acaagcaagc ctttagctaa attattttgt taatctttcg aataatgacg ctgttttttc
     3421 tcgccataaa gaggcggata ggcaatgatc caataaacgt cgcactgtat attctgcttc
     3481 tgcataacgc tttgaatagc ccatcgcatc ttgcatggct tctttatagc gcgctcgtac
     3541 ttccgctatt gctaattccg cctcttccgt aagcgcacaa tgttgcccaa tatcaaatat
     3601 cttatcgcct aatcgaccat cctgtggatc aaaaatatga ggttccgtac tatcaaaaat
     3661 acagaaattt agttctggga taatgaccat atcgacagat cctgcatcta agccacacca
     3721 tacaatttgg gcatccaatc ctcttgcatt cgcctcatct gctaagcctt tcatcaagga
     3781 ggatttgccc gtacccggtt tgcctttaat cattaatctt gtcgatatat tttttgtgat
     3841 gctttcaact gtattttctg cccctctagg cgttaacgtt ccaagtaaac gatgtgttcg
     3901 ttcacctgtt ttatttaaaa ctatagattg gaagacttcc aattttaaat tttccacctg
     3961 ttcatttaat gcctgccaat tcatgcagct ttgcgtcaca acctcccaat catcgtggag
     4021 tttgatagca tgatttagct tggcaataca tttatcacgc caagctgtac gttcctgtac
     4081 tgcatttgcc agttgctctc caattttctc aagctgggca tcctccaagc aatcataaaa
     4141 agacataaca cgatgtttcg tcccaagcaa tgttggctca atatcccatt ctgatgccca
     4201 gacatacagt ctattacaac cctttacata aacagcctcg actacttcct ctaataatgc
     4261 gtgcttaaac cattcgacag caaagccttg tttaacataa aaataaccca gctccttcaa
     4321 cagctctgat cctttagatg tagaggcacc ttgtaaaaaa taaactaact ccgcttcctc
     4381 catcatttct ttatataaat gtttcacacc ttgcccagtc aatgcgtgtc caaaataata
     4441 cgtcacattt ccgttcaaat gtcgttcctc cttttgtttc tgccttgcat tatatgaagg
     4501 aacactaaaa aagatgaaaa gctaccccta tccttaacag ataaaagtag ctttatagtt
     4561 taataaaaag gcttcatgtc ttctatatgg ccaatacatt tcattaatac tttgcggcaa
     4621 taaggtaatg aatattgcac aatatatcct gaagttaatg caattaatac tgttcccact
     4681 ccaactggcc cacctagtag ccaccctaca atggtcacta gaacttcaat acccattctg
     4741 gcagttttaa tagatccgcc aaatttttcg acgagtatca tcattaatgt atcacgaggg
     4801 cctgctccca tatttggagc aatatacata ccacagccaa agcttaaaac aaataaacca
     4861 ataataaaat atgtaatttg tagaccatat acatctgttg aaggcaataa ccagttaaat
     4921 acatcgatga atgaaccgat tagtagcatg ttcagccatg taccaatttt gggccatgtt
     4981 tgtaaaacaa tcgatgttga tgcgacaata aaaagacctg ttaatataga ccatgtacca
     5041 atcgttaatc cgaagttttg aaataatcct acatgcaaga catcccaagg acttgttcca
     5101 actattttcc ctttaatgga catcgtaata cccagtgaca tcacaatcaa gccaccaata
     5161 aaaaatgtcc agcgccaccc cattattttg cgcattccct atccctctct ttatgtttga
     5221 taatgctctt actgtatcat attttctgca aataacgtga aaacgtgctt atgaatggag
     5281 ggataaatga ccgtattctg tgaaaataaa aaactacccg attttactaa tgggtagttg
     5341 taattggcgc aagctgggcc tttgtaatat tcttcaaatc attaagttga acatgaattt
     5401 gcatgcctat tttccctgca cttacaataa tacagccttg ttcttgagca gtttcatcga
     5461 tgaccgtagg atataatttt ttcatgccta ccggcgagca tccaccacgg acatatcctg
     5521 tataactaag taaatctttt acaggtagca tatcaatctt cttttctcca actacctttg
     5581 cggcagcctt taaatccagc tccccagcca ctggaataac aaatacaaag agcttttggg
     5641 cacttgcctt tgctactaat gttttaaaaa cacgagcaac cggctgacca attttttcgg
     5701 caacagacac accatccact tgaccgtcgc caatttcata ctcaatcaca tcgaattgga
     5761 ttttttgctg ctctaataat cttatcgcat ttgttttggc atgctttgcc ttcgccataa
     5821 ccgtaatctc ctatctacaa cattaggcta tcaaagagaa catagaatca ttacctggat
     5881 gatagccatt tttcgtcatt tgaacatgtg ctgcatactt ttcagttgcc tgtttgaagg
     5941 ctctcaattt gaaagcagca tcatggctct taccgaaaat tgtatctgca aatgggtcca
     6001 atttcaattc cttcgagaaa cgttcaggaa cctttactgt agtcacctca ttgtcaaaag
     6061 gttggttctg ctcatctatt gcctcaacgg tagagttggc ttcatgtaaa atatgctgaa
     6121 tttgagcatc cacgttttct gctaaacgta tatcttgagc agaaggcttt gacggtgata
     6181 atgctgcatt tcgcacctgc tctaaaacct gtaatgtgtc attcatatct ggattattta
     6241 caacaggtga tccgtcatga tgaccacttg cccatttata agcttgctca tgtgcatgaa
     6301 cattctttga agtttgctgt aaatcttcca taatggcctg ctgttggggt gttactactt
     6361 ccgcatcttc ctgttgttgc tcatataaat cttgatctgt gcgtcctaat agtagatttt
     6421 caagctcaag caataaagga tttttctttg gttgaaaata cattgcattt tttcgatatg
     6481 catctcccgc ttctttacgc tgcaagaact tttttcgatt aaatggtgat gataatctct
     6541 cttgctccat tgaattatat attttcatag ttttcacctc atccttctat gttcatatgc
     6601 tattttgtta ctagatatga acatttttta tcactatatc tattccttcg aaacagcttc
     6661 tgtactctta ttatcggaat tttcattatt aaattcaagc ataaatgact actaaccacc
     6721 taaaggggta gagattaata tcatttttag atataaatac ctaatcccaa agaatatatg
     6781 cctcagtcct ttagtacttt catttcgatt tcaataaaaa ttactaccat tcgcacgaaa
     6841 taaatagtgt taataaataa aaaaaacagc ctctatataa accggctgct ttcttatttt
     6901 ttcggtgtaa tcaataggca cttataagct aaataaccga gccatgcacc aatagtattt
     6961 aaaattaaat catcaatatc cgcagatcct actgtaaaaa taaattggat cgtttccaca
     7021 ctaaggctgg caaaaaagcc taagcaaagt ataacgcctg ctttgcggaa tttcttcgat
     7081 agtaatggca gtaaaaagcc cataggggtg aaaattaata aattaccaag taagttaata
     7141 attatcgtat cccaattaaa atattgagag tagtttatat aacggaaaat cgtttcaaag
     7201 gggataaaat tagtagttaa tcgccaacta ctgtaatcaa acagccctaa gtcaccgacg
     7261 gaataatcac cttcccataa cacaacgact acattaacta aacgatcgat gaccaattta
     7321 taaaaagcca agcaagaata gatgctaaat aacatccaac ccactatttt tattggtaaa
     7381 taatatgtat caataacatc tcggtatggt aatgggagct tggcattacc ttgaacatcc
     7441 gttatgttgt tttttgacat gctaaacacc cgcttccctt tattccttcc catattttaa
     7501 tatgctcctt aagaccatgc aagtagctgt taactattta tcgactaaaa agactgcctc
     7561 ctgacagaga gacagccttc ccataagtat ttatactgga tttaccccat gcttacgttg
     7621 tgagaaaagt aagtattttg acatgtaaag ctctaaacga ttttcaagca ccttccgtaa
     7681 atcatttggc tcaatgacat catctataat taattctgat gctaatcgat acacatcaat
     7741 ctcttcttgg tactcttttc gtttttcagc tataaagctt gcttgctcct ctttcggaag
     7801 ctcggcaatt ttatttgcat aaactgcatt gactgcagct tctggaccca ttactgcaat
     7861 ttgagcattt gataatgcga tacagcagtc tggctcaaag gcaggaccag ccatagcata
     7921 taagccagca ccatatgctt tacgaacaat aaccgttagc tttggaacag ttgcttcact
     7981 catagcaaag atcatttttg cgccatgacg gataatacca gctttctcga cctgtgtgcc
     8041 gatcataaag cctgggacgt ccgccaagaa tagaagcggt atattgaaag catcacaaag
     8101 agagatgaac ttggccgctt tatctgcaga atcgtggaat aatacgcctc ccttaacgcg
     8161 cggttgattc gcgataatcc ctactgattg ccccttaata cgtgcaagac cagtaattaa
     8221 ttccggtgca aataatttct tcacttcaca aaacgaatct tcatcaataa tacgttcaat
     8281 taacttatac atatcaaaag gaacgttttg gttttgtggt atcaattcct caatcgattt
     8341 atcgaatgta gctggtggtt taggtgcctc tactttgcta cgttctgcat agttattagg
     8401 gaaatagcct aaatatttac gagcataggc aatggcctct tgttctgttt tggctagcac
     8461 atctccacag ccggaaactg aacagtgcat ttttgcgcca cccattgttt ctaaatctac
     8521 tttctctcca ataaccattt cagccatacg aggagatcct aaatacatag atgcgttccc
     8581 ttcaaccatg acaacgatat cacaaaatgc agggatgtag gcaccgcctg ccgcagacgg
     8641 tccgaatagt agacaaattt gtggtacttt acctgataac ttgacttggt tgtagaaaat
     8701 gcgacctgca cctcttctac ctgggaacat ttctagctga tctgtaatac gtgcacctgc
     8761 tgaatcaact aaatatagta atggacagtt aagtttttct gcagtttctt gaatacgaat
     8821 catcttttca accgtacgtt ttccccatga ccctgcttta atcgttgagt cattcgctaa
     8881 aacacaaacg gtacgaccat gaattttacc aatccctgtg acaacaccat cagcaggtaa
     8941 atcgcctgcc aaacagtttg cataaaggcc atcctctgat tgaagaccat catctaataa
     9001 taattcaaga cgttcacgta caaatagctt cccttgctgt gcatttttgt catgatattt
     9061 tggtaaacca ccagaaagaa ttttatcttt cattgtaggt ggcgtgtttt ctgttgaaat
     9121 attgctcatg ttttattcct ccctttgcca atgcgccaaa aaatcaatga gaatgcgctt
     9181 agatttccgt cagtgtgatt aatctgattg gattctcttc tttattttcc tgaataatgt
     9241 ggtgctcgct tctcttggaa ggctagtagt ccctctaatc ggtcctctgt agggatcagt
     9301 gcactatatg caagtgattc aatttttaaa ccggtagcta aatctacctc aacaccctga
     9361 ttcatagcca ctttagcctg tactaacgat aatggtgcat tttttgccat ttctagagca
     9421 agctgctgtg ccctttccat tacctcatgt gtctcatgaa catattcaac gatgccataa
     9481 tttttagctt cctcagcatt taagcgacgc gctgtataaa ttaattcctt tgccttccca
     9541 agaccaatta gtcgcggaag tcgttgcgtt cctcctgccc ctggaataat gccgagagag
     9601 gtttcagtga gacctaactt aacatgtgct gctgcgacac gtaaatcgca agctaaagct
     9661 aattctagac cgccaccaaa ggctactcca tttagcacag caatgacagg ctgagcgagt
     9721 gtctccactt ttgccactgt ggcaccaatc aactgcacga tttgcttcac ttgtcgatcg
     9781 gacatacctt tacgttcttt taaatcagca ccagcacaga atgctttttc tccagcacct
     9841 gttagtaaga ctactcgcac tgtcggatct ccgttgattt gatccagcgt atcagataac
     9901 tctcgtagta actgtacaga catcgcgttc gcagcctctg gtcttaaaag ggtaataagt
     9961 ccaatacttc cctctagtaa ttcaaagcga acaagttgag tcataatgga ttcgcactcc
    10021 tttcattacg gacaatcgcc atttgttttg aagctacagc tttgcctaat ttctgttcaa
    10081 taaagagtgc agcctctact attttttgtc gatctacacc agtttgaatg cccatttcat
    10141 caaataaata taataaatct tcggtagcta cattacctga agccccttta gcatatggac
    10201 agccccctaa accaccaagc gcactatcaa atttggttac acccatctct aaagatttca
    10261 taatgttagc cagcgccgtg ccacgtgtat catgaaaatg catagcaaaa ttatttgcgg
    10321 aatatctttt taatagttcc tctaaaagaa gctcaacttg agttggtaca cccacgccaa
    10381 tcgtgtcacc aagtgagatc tctgttacac ccatttccaa taatttatct gtaacacgca
    10441 gtactttatc aggatgtata tatccttcat agggacaacc aagaactgtg gagatatagc
    10501 ctcgaacctt tttctttgac gccttagctc ctaatactac ttcctctaaa ataggaaatg
    10561 tttcgtctat ggttttgtta atattacttt ggttatgact ttcactagca gacataaata
    10621 tacttacttc atctactcca gcctgtaacg ccctttctag gccacgcata ttaggtacaa
    10681 gtgctgcata agtaatatcc ttgttccttt taatggcttg aagaacctcg accgcatccg
    10741 ccaactgtgg aatccatttc ggatgtacaa atgaagtcac ctcgatgtaa tttaatccag
    10801 tttggcttaa caaattcact aattgtattt tatctgctgt tgtaatatgt gttttttcat
    10861 tttgtaaacc atcacgggga ccgacttctt tcattacgac atgcttaggt agctgcatta
    10921 agaggcctcc tcttattcaa tttctaaaat atcatcatca acgttaatga aatctccttc
    10981 attggcgata atttttgtta ccacaccatc ttcttctgct gcaatcggaa tttccatttt
    11041 cattgattct aaaatagcta catcttgacc tgccgttact ttctcacctt ctgctacgac
    11101 gattttccat actgtacctg ccatgcttgc ttttactgtt gccataatca gtcactccta
    11161 cttttaaatt aattatgcat tcgccctctc tatgaagcgc gaatgctctt caatacttac
    11221 tttgactctg ctaattgtgg taaataaaat tgttcgacaa attttgtagt cgtatagcct
    11281 tttaaaaact gttcatgtgt aacagttttt agcagcatcg gaatattcgt ttgaataccc
    11341 tccactttat atgctttcag tgcttggatt aatctttcac aggcaatgtc ccttgtttct
    11401 ccccacacta ctaatttact gatcattgga tcataaaatg gtgtaactgc tgaacctgcc
    11461 tctacaccac actcatgtcg aactccttcg cctgttggta attctagagc tgttatcgta
    11521 ccaggagacg ggaaaaatgt agaagggttt tcagcgtata tacgcacttc aatcgcatga
    11581 ccctgtttcg taatactttc ttttgtaaat gaaaggggtt gctgtgcagc gatttttaat
    11641 tgctcctcta ctaaatcaag tttcgtaatt tcctctgtca caggatgctc tacttgtaat
    11701 cttgtattca tttctaagaa ataaaagttt tgatcctcat ctaccaaata ctcgatcgtt
    11761 ccagcgttga tatagccaat atgcttcgcc gctttcactg acgcttctag catcttatct
    11821 cttgtctcct gtgaaatgaa tggtgatggt gcttcttcta ctactttttg atttcttcgt
    11881 tggatcgaac attcacgttc aaataacgga accacattgc cttgatgatc ggcaataatt
    11941 tgtacttcaa catggtgagg gctagcaata aatctctcca tgtacatcgt gccatcaccg
    12001 aaaaatgact gtgcacgttt ttgatttccc tcaaatgctt ttgctagttc ctctgcattt
    12061 tcaacaagtt gcataccgat accgccaccg cctgccgatg cctttaacat aattggatag
    12121 cctaaacgtt cagcgatttc agtagcttct tctgcatcct ttacaggtgt ctctacaccc
    12181 tctacaatgg gaacacctgc agctttcatt gttttacgtg cctctaattt acttcccatt
    12241 gatgcaataa catcagcact tggtccaata aaaattaaac cttcctcttc acagcgcttt
    12301 gcaaactctg catgttctga tagtagccca tagccaggat gaacagcctc gacgccattt
    12361 tctagtgcaa tttctagaat acgttctata tttaaatagc tttgtgctac aggtggtttc
    12421 cctacacaat acgcctcatc tgcatccttc acatgtaagc tttcagcatc tgcctcagaa
    12481 taaatagcaa ccgtatgaat atttaggcgc ctgcatgttc tgataatacg tctagcaatc
    12541 tccccacgat ttgcaattaa tactttattg aacatattta ctgcccctcc ttatctgacg
    12601 gtcatgacaa aatcttctcg taatttatat ttttgaacct tccctgaagc agtcattgga
    12661 taatgatcga taaagaaaat atgttttggg attttatgtc tagagatttt atcccgacaa
    12721 tattctcgaa tctcctcttc tgttgcctgc tcaccttctc ttaatataat ccaagctgcc
    12781 gcttcctccc catacacagg atcaggaacc ccagcaacct gaacatctga tatcttcgga
    12841 tgtgtataaa gaaactcttc catttcacga ggatataaat tttcaccacc gcgaataatc
    12901 atatctttta aacgacccgt tacacgcaca tagcccgctt catccatcgt tgccaaatca
    12961 cccgtatgca gccagccatc ttgatcaatg gcaagatcgg tttcttcttg gtttttatag
    13021 tagcctttca ttacatggta gcctcttgta catagctcgc cttgttcatt tgtaggtgct
    13081 tcctcgtttg tcccaggaac tacaattttc gcctctaagt ttggtaaggc acggccaacc
    13141 gtctccacct ttaatgctaa cgggtcatca gttctcgttt gcgtaataac tggggatgat
    13201 tctgtttgac catagcaaat cgtaatatct gtcataccca ttttctcaat gactgctttc
    13261 attacctcta tcggacaatt agagcccgcc atgactcctg tccgtagagt tgaaagattg
    13321 aaagactcaa aattcggtaa attaagctca ctaatgaaca tcgttggtac gccatgtaat
    13381 gctgtgcact tttcttgctg aaccgtcctt agcacctctt caggtgaaaa ttcttgtact
    13441 ggcaccatcg ttccaccact agttgtaatt gctaatgttc cgataacaca gccaaaacaa
    13501 tggaaaaatg gaacaggtat gcagaggcga tcctctgctg ttaaccgcat acactctgca
    13561 atgttgaccg cattgttcac taagttaaaa tgtgtaagca tcacaccttt aggaaaacct
    13621 gttgtaccag acgtatattg aatattaatc acatcatcat aatgaagaga ttgctctctt
    13681 tgttctaatt gttcctcggt cacctgatca gccgctgcta ctacatcgga ccaatttaat
    13741 acaccgggat acttagtctc gccgattaaa ataacatttt ttaataaagg tagtcgcttt
    13801 gattgcaaat tacctggtgc acaatgttca agctccggac ataactcttg aagtgtatgg
    13861 ataaaagaat ggtctcgata attttcaatt aaaaatatcg ttttggcatc agactgcttt
    13921 aatagatact ccaattcact agctcgataa ttagtgttta ccgtaacgat tggagctccc
    13981 attttccctg taccaaattg aagctgtacc cactcaggaa cattggtcgt ccatacagca
    14041 atatggtctc ctttttcaat tcctaaagcc attaagcccc ttgctaccaa tcgcgcttga
    14101 caatttagtt gctcataagt cattcgtaaa tttctatcag catagaccaa agcctcgttc
    14161 tgcgggtact ttttagattg ttcatctagc aattgaccaa ttgtttgata cacaagttct
    14221 gccatgaaga tcccccttgt ttatgctatt aaacttcttt cagcaatgag atgaatgcgg
    14281 atttaagcta cttttcagca ggtgtctcgg tatcagaaag aagtgctcta tgcagcacaa
    14341 agctgctccc ggacacaatg tgttgaaaat cattaacagc caattaaacg agaaataaca
    14401 agacgctgaa tttcagatgt tccttcacca atttccatta atttaatatc acgtaaatga
    14461 cgttctacat cgtattcttt catatatcca gaacctccat gaatttgaat ggcttgatta
    14521 catgtacgga agcccatttc agaagcaaat aatttagcca ttgccgcttc tttaccaaat
    14581 ggtttctttt gatcttttag ccatgccgct ttatgtacaa gcgtacgagc aagctctatt
    14641 tccatcgcca tatctgctaa tttaaattgg atcgcctgta gcttcgaaat aggtgcacca
    14701 aattgctcgc gttcttttgc gaacttcagt gccttctcat aagcggcctg tgcaataccg
    14761 acagaaagag ctgcaattga aatacgaccg ccatctaaag tgtttaaaaa ctggctaaag
    14821 cctcgctttt catcgcctaa tagattggat cgaggaacgc gaacattttg taaaacaatc
    14881 tcacatgtat tagaacctcg gacacccatt ttgtcatagt tacaattaat cgttacacct
    14941 ggagtattcg ttggcacaat aatagaagaa ataatctttt tgccatcctc gcgtttaccc
    15001 gttaccgcag ttacaataat ttgtcgagcg tatcctgcat tggtaatcca gcatttttct
    15061 ccattaataa cgtaatcatc tccatcaatg actgccgtag tgcgtgtacc gcctgcatct
    15121 gaacctgcat taggctctgt taaaccgaat gatcctaatg tctcaccctt tgccaatgga
    15181 acaagaaatt cctgcttttg ctcctccgta ccaaagttgt aaattggcga agctcctaag
    15241 ctaacagcag ctgcataact taagcctgtg cccccacatg cacggccaat ttcctctaca
    15301 gctaaagcgt aggacaccgt atcaccacct gagccaccat attcctcagg aaatgggata
    15361 cccaacaagc ctagttctgc catcttttta aagctctcta ttctcatcgt cgatgtctca
    15421 tcaacctcac gagcatacgg tttaatctct ttttcagcaa aatcacgtac catgtctcga
    15481 atcatcactt gctcttttgt taattcaaaa ttcatttcta atccccctaa tgtcaaattt
    15541 gccatagtag atttagctca aagataattt acttcaagta aataccgact agtcggtttg
    15601 taaaagcaaa taataaaacc agtgttttct actggctacc cctttatcat aaattgcttt
    15661 gcttcatcca ttgcttgttc tgtcacaatc gcacgcaata ccatgtcggt aaaaacatct
    15721 gtaatttgct ccattgttaa tggcccagat tgcttaaacc atttatatgt ccagttaatc
    15781 atccccacaa tcgccatcgt aacaatggta caaggcaatt ctgtacgaaa aaccttcgtt
    15841 tcttggcctt ctgctatcac tttttgtaag atgtcccgat aatgatctcg ttttttatga
    15901 atgatttcac tatactcctc tgagagtgaa cgactttctt cataaaaaat tgtaatatgt
    15961 gcttgataca tatcaaatac ttgtgtcagc gtttgtagca tcgcacataa ccgtggaatg
    16021 ggcgtgtcgt atttgtcata tgcatcctgt gattgttgaa taacatacga aataaagaca
    16081 tcatgaattt catacagcaa ttcatctttt gatttaaaat tatgataaaa tccacccttt
    16141 gatgccccta tatattcaac gatacgatca acagttacat tgtgataacc atcctgctga
    16201 aacagctcaa ctgaagcgtc tacaattctt tgctttaatg ttttctttac cataggccct
    16261 atcatccttc atctagctct atactccatc actccttata atcaggaaaa acttctttta
    16321 taaaagcatt ctattttttc ctaattataa aaatactatg acaatataaa tatagcattc
    16381 tcaaaatttg gtgtctagca acaaatagat ttttcctttt aatacgagca taaaaataac
    16441 attaaacaga atttaaagaa tcacaaacac atacatacct tatgttatgc cactcgtctt
    16501 catgacattt tttaaatttt gctcttctct ttacatcatt aaaccatttt tcactgctgt
    16561 tcaagaaacc atttataatc tcaaattaaa tggcaatacc cttaacttac tgtttattct
    16621 taaattatac gaaagaagag atttaaattt gcaaagatac actgtaatta acgaacacat
    16681 tttaattacc ctaaccctat cgttttaaaa aaaggacaag aagtattgta aggaaaagaa
    16741 tacactcaat tggatttttt ataaattcat tgttacaaat ccagaaggat ggattcagaa
    16801 gcaaatttta actacccgaa ataaccttta ctagtctccg cctccttaat tgtgctaaaa
    16861 agaatctgaa tgataggacc tttacataga aagagtttcc atgtttgggt gtttccttac
    16921 taatagttca aataaaaaaa cagccagcac acagctgact gtttttgttg cctagcgacg
    16981 tcctactctc acagggggaa gcccccaact accatcggcg ctaaagagct taacttccgt
    17041 gttcggtatg ggaacgggtg tgacctcttt gccatcatca ctagactatt ttcggctttc
    17101 aatacacggc ataaaactgt gtcttgaagc tctttttatt gaaaggattg ttctttcaaa
    17161 actggataaa cggttcattg aatgcttcaa acattttggt taagtcctcg atcgattagt
    17221 attcgtcagc tccatgtgtc accacacttc cacctcgaac ctatctacct catcgtcttt
    17281 gagggatctt acttacttgc gtaatgggaa atctcatctt gaggggggct tcatgcttag
    17341 atgctttcag cacttatccc gtccacacat agctacccag cgatgccttt ggcaagacaa
    17401 ctggtacacc agcggtgtgt ccatcccggt cctctcgtac taaggacagc tcctctcaaa
    17461 tttcctacgc ccacgacgga tagggaccga actgtctcac gacgttctga acccagctcg
    17521 cgtaccgctt taatgggcga acagcccaac ccttgggacc gactacagcc ccaggatgcg
    17581 atgagccgac atcgaggtgc caaacctccc cgtcgatgtg gactcttggg ggagataagc
    17641 ctgttatccc cggggtagct tttatccgtt gagcgatggc ccttccatgc ggaaccaccg
    17701 gatcactaag cccgtctttc gaccctgctc gacttgtagg tctcgcagtc aagctccctt
    17761 gtgcctttac actctacgaa tgatttccaa ccattctgag ggaacctttg ggcgcctccg
    17821 ttacctttta ggaggcgacc gccccagtca aactgtccgc ctgacactgt ctcctgcccc
    17881 gctaaggggc atgggttaga atttcaatac aaccagggta gtatcccacc gacgcctcct
    17941 tcgaagctgg cgctccgaga tctctggctc ctacctatcc tgtacaagtt gtaccaaaat
    18001 tcaatatcag gctacagtaa agctccacgg ggtctttccg tcctgtcgcg ggtaacctgc
    18061 atcttcacag gtactataat ttcaccgagt ctctcgttga gacagtgccc agatcgttac
    18121 gcctttcgtg cgggtcggaa cttacccgac aaggaatttc gctaccttag gaccgttata
    18181 gttacggccg ccgtttactg gggcttcaat tcgtagcttc gcttgcgcta accactcctc
    18241 ttaaccttcc agcaccgggc aggcgtcagc ccctatacgt caccttacgg ttttgcagag
    18301 acctgtgttt ttgctaaaca gtcgcctggg cctattcact gcggctctca tgcgcttgca
    18361 cgctcaagag caccccttct cccgaagtta cggggtcatt ttgccgagtt ccttaacgag
    18421 agttctctcg cacaccttag gattctctcc tcgactacct gtgtcggttt gcggtacggg
    18481 cacctctcac ctcgatagag gcttttcttg gcagtgtgaa atcaggaact tcgtccatac
    18541 ggactcgcca tcacagctca acgttacagt gtgcggattt gcctacacac acgccttact
    18601 gcttggacgc gcataaccaa cagcgcgctt accctatcct actgcgtccc cccatttctc
    18661 aaacggtgag gaggtggtac aggaatatca acctgttgtc catcgcctac gcctatcggc
    18721 ctcggcttag gtcccgacta accctgagcg gacgagcctt cctcaggaaa ccttagtcat
    18781 acggtggacg ggattctcac ccgtctttcg ctactcatac cggcattctc acttctaagc
    18841 gctccaccag tccttccggt ctgacttcaa cgcacttaga acgctctcct accactgaca
    18901 tcgtagatgt caatccacag cttcggtgaa tcgtttagcc ccgatacatt ttcggcgcag
    18961 cgtcactcga ccagtgagct attacgcact ctttaaatga tggctgcttc taagccaaca
    19021 tcctggttgt ctgtgcaacg ccacatcctt ttccacttaa cgattacttt gggaccttag
    19081 ctggtggtct gggctgtttc ccttttgact acggatctta tcactcgcag tctgactccc
    19141 gtgtataaat atctggcatt cggagtttgt ctgaattcgg taaaccggga tggcccccta
    19201 gtccaaacag tgctctacct ccagtattct catcacgagg ctagccctaa agctatttcg
    19261 gagagaacca gctatctcca agttcgattg gaatttctcc gctacccaca cctcatcccc
    19321 gcacttttca acgtgcgtgg gttcgggcct ccagtaagtg ttaccttacc ttcaccctgg
    19381 acatgggtag atcacctggt ttcgggtcta cgaccacgta ctaattcgcc ctattcagac
    19441 tcgctttcgc tgcggctccg ccttctaaag cttaacctcg cacgtaatcg taactcgccg
    19501 gttcattcta caaaaggcac gctatcaccc attaacgggc tctaactact tgtaggcaca
    19561 cggtttcagg atctctttca ctccccttcc ggggtgcttt tcacctttcc ctcacggtac
    19621 tggttcacta tcggtcacta ggtagtattt agccttggga gatggtcctc ccagattccg
    19681 acggaatttc acgtgttccg ccgtactcag gatccactca ggagggaacg aactttcgac
    19741 tacagggctt ttacctgctc tggcggacct ttccaagtcg cttcatctaa ctcgctcttt
    19801 tgtaactccg tattgagtgt cctacaaccc caagaggcaa gcctcttggt ttgggctctt
    19861 cccgtttcgc tcgccgctac tcagggaatc gatttttctt tctcttcctc caggtactta
    19921 gatgtttcag ttccctgggt ctgccttcaa gacgctatgt attcacgtca agatactacg
    19981 cgattaaacg tagtgggttc ccccattcgg aaatctccgg atcaaagctc acttacagct
    20041 ccccgaagca tatcggtgtt agtgccgtcc ttcttcggct cctagtgcca aggcattcgc
    20101 cgtgcgccct taataactta acctatcagc ttccaataca catcacattt cgttgtcagc
    20161 ttcactcgtt caatcagtca cgtactaaag tacgctccat catttactcg attgcttcct
    20221 agaactgttc gtgtcttgaa accttttaat gttattaagc ctataaaaaa acttaaaaaa
    20281 taaatgtgtt tgttacaatt tcaatgtcgt tttatccagt tttcaaagaa caagttttga
    20341 agtatttcat tcagaagaat gaaccttcaa aactgaacgc aaaacgtaat cttacaaacc
    20401 caaggtttgt attccgaaaa tatccttaga aaggaggtga tccagccgca ccttccgata
    20461 cggctacctt gttacgactt caccccaatc atctatccca ccttcggcgg ctggctccaa
    20521 aaggttacct caccgacttc gggtgttaca aactctcgtg gtgtgacggg cggtgtgtac
    20581 aaggcccggg aacgtattca ccgcggcatg ctgatccgcg attactagcg attccggctt
    20641 catgtaggcg agttgcagcc tacaatccga actgagaacg actttatcgg attagctccc
    20701 tctcgcgagt tggcaaccgt ttgtatcgtc cattgtagca cgtgtgtagc ccaggtcata
    20761 aggggcatga tgatttgacg tcatccccac cttcctccgg tttatcaccg gcagtcacct
    20821 tagagtgccc aactaaatga tggcaactaa gatcaagggt tgcgctcgtt gcgggactta
    20881 acccaacatc tcacgacacg agctgacgac aaccatgcac cacctgtcac cgttgccccc
    20941 gaaggggaaa ccatatctct acagtggtca acgggatgtc aagacctggt aaggttcttc
    21001 gcgttgcttc gaattaaacc acatgctcca ccgcttgtgc gggcccccgt caattccttt
    21061 gagtttcagt cttgcgaccg tactccccag gcggagtgct taatgcgtta gctgcagcac
    21121 taaggggcgg aaacccccta acacttagca ctcatcgttt acggcgtgga ctaccagggt
    21181 atctaatcct gtttgctccc cacgctttcg cgcctcagtg tcagttacag accagatagt
    21241 cgccttcgcc actggtgttc ctccaaatct ctacgcattt caccgctaca cttggaattc
    21301 cactatcctc ttctgcactc aagtctccca gtttccaatg accctccacg gttgagccgt
    21361 gggctttcac atcagactta agaaaccacc tgcgcgcgct ttacgcccaa taattccgga
    21421 caacgcttgc cacctacgta ttaccgcggc tgctggcacg tagttagccg tggctttcta
    21481 ataaggtacc gtcaaggtac agccagttac tactgtactt gttcttccct tacaacagag
    21541 ttttacgaac cgaaatcctt cttcactcac gcggcgttgc tccatcaggc tttcgcccat
    21601 tgtggaagat tccctactgc tgcctcccgt aggagtctgg gccgtgtctc agtcccagtg
    21661 tggccgatca ccctctcagg tcggctacgc atcgtcgcct tggtgagccg ttacctcacc
    21721 aactagctaa tgcgccgcgg gcccatccta tagcgacagc cgaaaccgtc tttcagtgtt
    21781 tcaccatgag gtgaaacaga ttattcggta ttagccccgg tttcccggag ttatcccaaa
    21841 ctataaggta ggttgcccac gtgttactca cccgtccgcc gctaacgtcg aaggagcaag
    21901 ctccttctct gttcgctcga cttgcatgta ttaggcacgc cgccagcgtt cgtcctgagc
    21961 caggatcaaa ctctccataa aagaaatttg attagctcaa attgttttgc tggcatcaat
    22021 tttgatgtcc aaaattttgt ttcgttcact agctaggcta gctacttaaa actttattga
    22081 ttacgttttg cttgttcagt tttcaaggtt catttttatt tatcgtcctg cgacaagaat
    22141 taatattatc agaatgtaat acaatagtca acaactattt taatatattt ttttcgttgt
    22201 cgaagtgaca gaatatataa tataacataa taacatttta tctgtcagca ctttccttca
    22261 aatgtttaac actacgaatc gctgctccta tttcgttagg cggtgtaaag gtgaaaagaa
    22321 tgagcggtgt actttaatgt ccactgttgt atttagtttt aaagatacat cctcaagtta
    22381 gagaatcggc aacttttgtt actgaaagac atccacatcg tatgagtatt ttgcaaatga
    22441 gatatatctt ccagtcgcgc tggaattatg ggaaatttgc agccccatca ataaaaacac
    22501 aggtacgcta cacatctatg aaacaatggc gcactcattg aagtaattca aattttgatg
    22561 agagcatgat aaaagtgtca ctactaggaa aataccagaa gtacgtttag cttatttaaa
    22621 actgaaaaat accttattta aaatcgctaa agtcattgaa tcataatccc aaacccggac
    22681 ttaaataata ttaaaagaaa ccagacacgt cttttgaacg ttcgggtttc ttttaaatta
    22741 atatttattt ttctacatta aagcctttta ataaatctgc aaaagcatta ttcaaaggct
    22801 ctgcttcttt ctcttgctgt ttcatgtact tttgtacact acgtttatcc actttacctc
    22861 caccttcttt tttacggcga gcttcaaaag cagataactt ctcacgatag ccacacttac
    22921 atacgaagat ttgaccatca ccttcgccac gtaattcaag ctttttctta cactgaggac
    22981 aacgtgcatt cgtcacacgc gacacattct tacggtgacc acattcacga tcttgacaaa
    23041 caaggatttt accttttttc ccattcactt caagcattgg cttaccgcat tcagggcaag
    23101 tttttgttga aatattatca tgcttaaatc tcttatcgct atttttaata tcagctacaa
    23161 tttcttttgt atgttgcttc atttcattaa tgaaggtttc ttttttcagt ttacctttag
    23221 cgattaattc taacttttgc tcccattcgg ctgttgtttc aggagatttt aactcattag
    23281 gaactaaatc aagtaactga cgacctttag aagtgatatg aatatcctta ccacgctttt
    23341 caattaggaa tgaattgaat aacttatcaa taatatcggc tcgtgttgcc accgttccta
    23401 atccacctgt cgattttaac gtatcagcaa gctgcttatt ttgcgtgttc atatactttg
    23461 taggattttc cattgccgat aaaagtgtag cctcagtgaa acgtgctgga ggcttcgttt
    23521 gacctgatgt ttgagtaatt aaatttactt ttaatacttg gcctttttcg agacgaggca
    23581 ataattgttc cttcacatct tcgtttgatt cctcatcatc aaagcgattt gagtaaactt
    23641 ctttccatcc ggcagaaatt actgttttac cacgagcaat gaatttttcg ttaccaatat
    23701 gagcttgcac tgttaactgt tcatattcat aagctgggaa aagcaccgct aagaaacgtt
    23761 ttacaactaa atcataaatt ttacgttctt tatcggtaaa gtttgcaaag tttacgtatt
    23821 cttctgtagg aataattgca tggtgatcag ataccttgct gtcatccaca aatgatttat
    23881 tcgctttaat tggttttgaa agcactttgt ttgctaacgt tcgatattct cctataccgc
    23941 atgcttttaa tcgttctgga agggtgctaa cgatgtctga agatacatat cgcgaatcag
    24001 tacgaggata agtaagcact ttatgagact catatagttt ttgcatgata tttaatgttt
    24061 ctttagctga gtatccaaat attttgtttg catcacgctg tagctccgtt aaatcatata
    24121 accctggaga gaaagatttt ttcggcttac gttcaatttc gattactttt gcatcttgtt
    24181 tatctaatga attaacaaca gcatctactt tttctttact aaagc
//
