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Overview
1.1
1.2
1.3

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP016839.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | RRE-containing | 180,698 | 201,831 |
Region 1.2 | RiPP-like | 309,614 | 319,901 |
Region 1.3 | ladderane | 2,435,033 | 2,476,145 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | RRE-containing | 180,698 | 201,831 |
Region 1.2 | RiPP-like | 309,614 | 319,901 |
Region 1.3 | ladderane | 2,435,033 | 2,476,145 |

No secondary metabolite regions were found in these records:
  NZ_CP016840.1

Compact view
NZ_CP016839.1 - Region 1 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 180,698 - 201,831 nt. (total: 21,134 nt) Show pHMM detection rules used
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000585.1 |  | 0.21 | RiPP | microcin C7 | Escherichia coli
BGC0000487.1 |  | 0.17 | RiPP | carnocyclin | Carnobacterium maltaromaticum
BGC0000500.1 |  | 0.16 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000498.1 |  | 0.16 | RiPP | bovicin HJ50 | Streptococcus equinus
BGC0000561.1 |  | 0.16 | RiPP | thermophilin 1277 | Streptococcus thermophilus
BGC0000528.1 |  | 0.16 | RiPP | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0000504.1 |  | 0.16 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000521.1 |  | 0.16 | RiPP | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0001551.1 |  | 0.16 | RiPP | citrulassin E | Streptomyces glaucescens
BGC0000592.1 |  | 0.16 | RiPP | microviridin B | Microcystis aeruginosa NIES-298

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000585.1 |  | 0.53 | RiPP | microcin C7 | Escherichia coli
BGC0000487.1 |  | 0.48 | RiPP | carnocyclin | Carnobacterium maltaromaticum
BGC0000500.1 |  | 0.47 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000498.1 |  | 0.47 | RiPP | bovicin HJ50 | Streptococcus equinus
BGC0000561.1 |  | 0.47 | RiPP | thermophilin 1277 | Streptococcus thermophilus
BGC0000528.1 |  | 0.47 | RiPP | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0000504.1 |  | 0.47 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000521.1 |  | 0.47 | RiPP | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0001551.1 |  | 0.46 | RiPP | citrulassin E | Streptomyces glaucescens
BGC0000592.1 |  | 0.46 | RiPP | microviridin B | Microcystis aeruginosa NIES-298

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP016839.1 - Region 2 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 309,614 - 319,901 nt. (total: 10,288 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000501.1 |  | 0.16 | RiPP | catenulipeptin | Catenulispora acidiphila DSM 44928
BGC0001639.1 |  | 0.15 | RiPP | klebsidin | Klebsiella pneumoniae
BGC0000551.1 |  | 0.15 | RiPP | SapB | Streptomyces coelicolor A3(2)
BGC0000554.1 |  | 0.15 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000916.1 |  | 0.15 | Other | molybdenum cofactor | Staphylococcus carnosus
BGC0000548.1 |  | 0.15 | RiPP | salivaricin A | Streptococcus salivarius
BGC0000294.1 |  | 0.15 | NRP | acinetobactin | Acinetobacter baumannii
BGC0001120.1 |  | 0.14 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001138.1 |  | 0.14 | Other (Nucleoside) | a201a | Marinactinospora thermotolerans
BGC0002009.1 |  | 0.14 | Polyketide | kanglemycin A, kanglemycin V1, kanglemycin V2 | Amycolatopsis vancoresmycina

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000501.1 |  | 0.46 | RiPP | catenulipeptin | Catenulispora acidiphila DSM 44928
BGC0001639.1 |  | 0.46 | RiPP | klebsidin | Klebsiella pneumoniae
BGC0000551.1 |  | 0.46 | RiPP | SapB | Streptomyces coelicolor A3(2)
BGC0000554.1 |  | 0.46 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000916.1 |  | 0.45 | Other | molybdenum cofactor | Staphylococcus carnosus
BGC0000548.1 |  | 0.45 | RiPP | salivaricin A | Streptococcus salivarius
BGC0000294.1 |  | 0.45 | NRP | acinetobactin | Acinetobacter baumannii
BGC0001120.1 |  | 0.44 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001138.1 |  | 0.43 | Other (Nucleoside) | a201a | Marinactinospora thermotolerans
BGC0002009.1 |  | 0.43 | Polyketide | kanglemycin A, kanglemycin V1, kanglemycin V2 | Amycolatopsis vancoresmycina

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP016839.1 - Region 3 - ladderane
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,435,033 - 2,476,145 nt. (total: 41,113 nt) Show pHMM detection rules used
ladderane: ladderane

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ladderane | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000248.1 |  | 0.17 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0000554.1 |  | 0.17 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001525.1 |  | 0.17 | Other | bartoloside 2, bartoloside 3, bartoloside 4 | Synechocystis salina LEGE 06155
BGC0000616.1 |  | 0.17 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0001526.1 |  | 0.16 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099
BGC0001579.1 |  | 0.16 | RiPP | duramycin | Streptomyces cinnamoneus
BGC0000498.1 |  | 0.16 | RiPP | bovicin HJ50 | Streptococcus equinus
BGC0000561.1 |  | 0.16 | RiPP | thermophilin 1277 | Streptococcus thermophilus
BGC0001779.1 |  | 0.16 | RiPP | siamycin | Streptomyces nodosus
BGC0001591.1 |  | 0.16 | Other | fatty acid enol ester | uncultured bacterium CSLC2

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000248.1 |  | 0.48 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0000554.1 |  | 0.48 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001525.1 |  | 0.48 | Other | bartoloside 2, bartoloside 3, bartoloside 4 | Synechocystis salina LEGE 06155
BGC0000616.1 |  | 0.47 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0001526.1 |  | 0.47 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099
BGC0001579.1 |  | 0.47 | RiPP | duramycin | Streptomyces cinnamoneus
BGC0000498.1 |  | 0.47 | RiPP | bovicin HJ50 | Streptococcus equinus
BGC0000561.1 |  | 0.47 | RiPP | thermophilin 1277 | Streptococcus thermophilus
BGC0001779.1 |  | 0.47 | RiPP | siamycin | Streptomyces nodosus
BGC0001591.1 |  | 0.47 | Other | fatty acid enol ester | uncultured bacterium CSLC2

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names