LOCUS       c00008_NZ_AUMN..       11851 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_AUMN01000008.1 Arthrobacter castelli DSM 16402
            H535DRAFT_scaffold00008.8_C, whole genome shotgun sequence.
ACCESSION   NZ_AUMN01000008
VERSION     NZ_AUMN01000008
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:13:29
            Original ID  :: NZ_AUMN01000008.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 126869
            Orig. end    :: 138720
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11851
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[131869:133720](+)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="5000"
                     /product="siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..6851
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="5000"
                     /product="siderophore"
                     /protocluster_number="1"
     cand_cluster    1..11851
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11851
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="siderophore"
                     /region_number="1"
                     /rules="IucA_IucC"
                     /tool="antismash"
     CDS             323..1246
                     /locus_tag="ctg8_131"
                     /transl_table=11
                     /translation="VTPSRWRELAPGQRAQLTIVDRASVDEDPVDSGPSSRVVFETAES
                     VIEAPNWNPGGDWLVFNSDGLLYRIKADGSGPPIRIPTGELNDSNNDHVLSPDGTCLFT
                     SSQNGHLYRVPADGGPAQRVSDDADGLQARYLHGISPDGTTLALIGCHQLRAAERFNIF
                     TLSLIDGSTRQLTDSDHHHDGAEYSPDGEWIYFNSDRASTAKGHSQIFRMRPDGRDPQQ
                     LTFDTRVNWFPHLSPDGSSMVYLSYQSSVVGHPANKDVLLRQADPEGESVRTVAGVFGG
                     QGTINVNSWAPDSQRFAYVAYPVRNR"
     PFAM_domain     839..958
                     /aSDomain="PD40"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07676.14"
                     /description="WD40-like Beta Propeller Repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_131_0001"
                     /evalue="1.10E-05"
                     /label="ctg8_131"
                     /locus_tag="ctg8_131"
                     /protein_end="212"
                     /protein_start="172"
                     /score="25.4"
                     /tool="antismash"
                     /translation="RQLTDSDHHHDGAEYSPDGEWIYFNSDRASTAKGHSQIFR"
     CDS             1606..3141
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180:Decarboxylase, pyridoxal-dependent (Score: 376.4;
                     E-value: 3e-114)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_132"
                     /transl_table=11
                     /translation="VSLSSSTEEETRFADQVESTLSATNQLLNSRTAPHYAAEVMSGIR
                     AVSAQVSAGTTPCTGPTPESLHHEVSAIDLDHPLSSPADALAEVERVYLRDAVYFHDVK
                     YAAHLNCPVAIPALVGEAVLSAVNTSMDTWDQSTAATHMEQHLIQWTAERLGLGDDADG
                     VFTSGGSQSNLQALLMARNRLHARLRSAHPDRPPRLADVLGGFRIFASDVSHFSVQKSA
                     AILGLGPEAVVVVPSDGQKRMDTDALEREVARCRQEGLLPMAVVGTAGTTDFGSFDPLV
                     RLADICGVEDIWLHIDAAYGGGLITSQRHRHLLAGTGAADSVTIDFHKTFFQPVSSSAI
                     LVRDRAQLEHVTYYADYLNPPGGPPNQVDKSLQTTRRFDALKLWLTLRTMGADAVGALL
                     DEVIELATGCAGSLGAMEDFDVVVRPAFSTVVFRYLPPGAPDETADRINQQIRSELFDS
                     GEAIIGGTIVEGRHYLKFTLLNAETTMADVKEMIELIRQRGSHHLASEAMHHG"
     PFAM_domain     1906..2907
                     /aSDomain="Pyridoxal_deC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00282.21"
                     /description="Pyridoxal-dependent decarboxylase conserved
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_132_0002"
                     /evalue="5.80E-67"
                     /label="ctg8_132"
                     /locus_tag="ctg8_132"
                     /protein_end="434"
                     /protein_start="100"
                     /score="226.1"
                     /tool="antismash"
                     /translation="HDVKYAAHLNCPVAIPALVGEAVLSAVNTSMDTWDQSTAATHMEQ
                     HLIQWTAERLGLGDDADGVFTSGGSQSNLQALLMARNRLHARLRSAHPDRPPRLADVLG
                     GFRIFASDVSHFSVQKSAAILGLGPEAVVVVPSDGQKRMDTDALEREVARCRQEGLLPM
                     AVVGTAGTTDFGSFDPLVRLADICGVEDIWLHIDAAYGGGLITSQRHRHLLAGTGAADS
                     VTIDFHKTFFQPVSSSAILVRDRAQLEHVTYYADYLNPPGGPPNQVDKSLQTTRRFDAL
                     KLWLTLRTMGADAVGALLDEVIELATGCAGSLGAMEDFDVVVRPAFSTVVFRY"
     CDS             3134..4453
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080:lysine/ornithine N-monooxygenase (Score: 396.4;
                     E-value: 2.2e-120)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_133"
                     /transl_table=11
                     /translation="MDEPYDFIGIGLGPFNLGLAALTAPITCLNGLFLEQESHFDWHPG
                     MMLDSSTLQVPFMADLVTMADPTSEFSFLNFLKSTGRIYPFYIRERFNPLRAEYNQYCQ
                     WVAGRLPMLRFGSTVDWIEYDDGAQAYSVRLATGERFQARRLVLGTGTRPAVPEVCGGL
                     EGPALHSADYLHRREELLQRSSITVVGSGQSAAEIYFDLLQEMGGGDFELNWVTRSGRF
                     FPLEYAKLTLEMTSPEYCAYFRSLPETTRDRLNADQQNLYKGIDESLINEIYDLLYQKS
                     LHGPVNTNLLSNSDLQAAHWDGAAYSLEFLHREQDRSYGLRTEALVLATGYQSSEPDFL
                     AGLEPWLNRDGRGRLAADGHYRVDAEAGHGAIYVQNAELNTHGFVAPDLGMGAYRNSCI
                     IRNMLGWEYYPVESRIGFQQFGAPVPDREEPLPAVEGAPL"
     PFAM_domain     3143..4132
                     /aSDomain="K_oxygenase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13434.8"
                     /description="L-lysine 6-monooxygenase (NADPH-requiring)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_133_0003"
                     /evalue="3.60E-116"
                     /label="ctg8_133"
                     /locus_tag="ctg8_133"
                     /protein_end="333"
                     /protein_start="3"
                     /score="388.1"
                     /tool="antismash"
                     /translation="PYDFIGIGLGPFNLGLAALTAPITCLNGLFLEQESHFDWHPGMML
                     DSSTLQVPFMADLVTMADPTSEFSFLNFLKSTGRIYPFYIRERFNPLRAEYNQYCQWVA
                     GRLPMLRFGSTVDWIEYDDGAQAYSVRLATGERFQARRLVLGTGTRPAVPEVCGGLEGP
                     ALHSADYLHRREELLQRSSITVVGSGQSAAEIYFDLLQEMGGGDFELNWVTRSGRFFPL
                     EYAKLTLEMTSPEYCAYFRSLPETTRDRLNADQQNLYKGIDESLINEIYDLLYQKSLHG
                     PVNTNLLSNSDLQAAHWDGAAYSLEFLHREQDRSYGLRTEALVLATGYQ"
     CDS             4450..5004
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203:putative siderophore biosynthesis protein (Score:
                     135.1; E-value: 7.1e-41)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_134"
                     /transl_table=11
                     /translation="VNFPLRPVDPDADARLLHSWFSQDYASFWDMLDAGVDDVRREHRA
                     IAASDHHHALLGFDGGAPVFLMERYDPARSPIAGCYEATAADVGMHLLVAPPAAPVPGY
                     TRSVMAAVLDHLFEDPTVERVVVEPDIRNHKIQALNDAAGFRPVTNIELPDKTAVLSIC
                     TRTDYAAARNQLARRSQEATA"
     PFAM_domain     4474..4905
                     /aSDomain="Acetyltransf_8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13523.8"
                     /description="Acetyltransferase (GNAT) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_134_0004"
                     /evalue="1.30E-46"
                     /label="ctg8_134"
                     /locus_tag="ctg8_134"
                     /protein_end="152"
                     /protein_start="8"
                     /score="158.0"
                     /tool="antismash"
                     /translation="DPDADARLLHSWFSQDYASFWDMLDAGVDDVRREHRAIAASDHHH
                     ALLGFDGGAPVFLMERYDPARSPIAGCYEATAADVGMHLLVAPPAAPVPGYTRSVMAAV
                     LDHLFEDPTVERVVVEPDIRNHKIQALNDAAGFRPVTNIE"
     CDS             5001..6851
                     /gene_functions="biosynthetic (rule-based-clusters)
                     siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_135"
                     /sec_met_domain="IucA_IucC (E-value: 7.9e-81, bitscore:
                     264.8, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VTITELEEVQEPAPSTTVDRQEHLTACVWAEANRRLVAKAIAEFS
                     HERLLAPEQADEQRLFRITSDDGGTGYRFEATRRALDHWDIAGDSIQRRRDGQNLEPDA
                     LDFMLEFRGQLGIAEDVLPVYLEEISSTLAGAAYKLQNPAPDSAALARAGGTPAAAAQR
                     IERAMAEGHPCFVANNGRLGFGAGDYRAYAPEAGAAVQLVWIAVHRSRAVFTSSRTLGE
                     AELYRSELGPQMLDGFAAQLASQGLEARDYLYMPVHPWQWENKLSITFAAEVAHRNVVC
                     LGVGADRYQAQQSIRTFFNLDVPQRCYVKTSLSVLNMGFMRGLSAEYMKATPAINDWLH
                     RLVEADETLRRSGFTVLRELAAVGYHNDYYEAATTAGSPYRKMLAALWRESPAGQLREG
                     EQLATMASLLHRDRNGVPFVSALMAQSGLSAKEWLEHYLRAYLMPLVHCLCAYDLAFMP
                     HGENIILVLDDGVPVRVLMKDIGEEIAVIGDGIELPDEVSRIRVDVPSEEQVLTIFTDV
                     FDSFFRFLSAILAGDGQLSEDAFWTAVANCLHQYRDASPETAEAFDRHEFFAAGFPLSC
                     LNRLQLRNNREMLDLNDPSGSLQHAGRVANPIARFSGQAA"
     PFAM_domain     5484..6230
                     /aSDomain="IucA_IucC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04183.14"
                     /description="IucA / IucC family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_135_0005"
                     /evalue="5.80E-78"
                     /label="ctg8_135"
                     /locus_tag="ctg8_135"
                     /protein_end="410"
                     /protein_start="161"
                     /score="261.9"
                     /tool="antismash"
                     /translation="QRIERAMAEGHPCFVANNGRLGFGAGDYRAYAPEAGAAVQLVWIA
                     VHRSRAVFTSSRTLGEAELYRSELGPQMLDGFAAQLASQGLEARDYLYMPVHPWQWENK
                     LSITFAAEVAHRNVVCLGVGADRYQAQQSIRTFFNLDVPQRCYVKTSLSVLNMGFMRGL
                     SAEYMKATPAINDWLHRLVEADETLRRSGFTVLRELAAVGYHNDYYEAATTAGSPYRKM
                     LAALWRESPAGQLREGEQLATMASLLH"
     PFAM_domain     6294..6767
                     /aSDomain="FhuF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06276.14"
                     /description="Ferric iron reductase FhuF-like transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_135_0006"
                     /evalue="3.80E-39"
                     /label="ctg8_135"
                     /locus_tag="ctg8_135"
                     /protein_end="589"
                     /protein_start="431"
                     /score="134.8"
                     /tool="antismash"
                     /translation="EWLEHYLRAYLMPLVHCLCAYDLAFMPHGENIILVLDDGVPVRVL
                     MKDIGEEIAVIGDGIELPDEVSRIRVDVPSEEQVLTIFTDVFDSFFRFLSAILAGDGQL
                     SEDAFWTAVANCLHQYRDASPETAEAFDRHEFFAAGFPLSCLNRLQLRNNREML"
     CDS             complement(6889..7287)
                     /locus_tag="ctg8_136"
                     /transl_table=11
                     /translation="MSVVVGYIPTPEGTAALNRAVEEARQRAVHLIVVNSSRGSSHPDK
                     NYVDDSESAALDERLKTEGVEHTLVQQLGDIDAGEEVLNSAERYHADLIVIGLRHRTPV
                     GKLIMGSTAQRILLEAPCPVLAVKADYS"
     PFAM_domain     complement(6904..7281)
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00582.28"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_136_0007"
                     /evalue="1.20E-19"
                     /label="ctg8_136"
                     /locus_tag="ctg8_136"
                     /protein_end="128"
                     /protein_start="2"
                     /score="71.3"
                     /tool="antismash"
                     /translation="VVVGYIPTPEGTAALNRAVEEARQRAVHLIVVNSSRGSSHPDKNY
                     VDDSESAALDERLKTEGVEHTLVQQLGDIDAGEEVLNSAERYHADLIVIGLRHRTPVGK
                     LIMGSTAQRILLEAPCPVLAVK"
     CDS             complement(7357..8778)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038:phenylalanine-specific permease (Score: 233.8;
                     E-value: 4.4e-71)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_137"
                     /transl_table=11
                     /translation="MGNPTDTKQGPGQPEPELKKALGFKLLLLFIVGDILGTGVYALTG
                     DVAGEIGGAAWAPVLLAFAVATVTAFSYLELVTKYPQAAGAALYTHKAFGIHFVTFLVT
                     FAVLSSGITSASTASKFLAENFIVGFNLDWGQFGVTMIAVVFLGLLAVINLRGVGESLK
                     LNVVLTLIELTGLLIVILVGFWAMAQGNVDFGRVMVFETSGDKTVFLALTAATSLAFFS
                     MVGFEDSVNMAEETKDPVKTFPKVMLTGLSITALVYVLVSIAAVAIVPVGRLEDSPTPL
                     LEVVQVGAPGIPIDAIYPFMSMFAVANTALINMMMASRLIYGMAKQDVLPRSLGKVLPG
                     RRSPWSSIIFTTLIAFGLIITVTNFMGAETVSALGGTTALLLLAVFTVVNIAAIVLRRF
                     PVDREHFRAPTVLPYIGALTCAFLVGPWAQDPIEYRIAGVMLALGVVLWAITWFWNRGV
                     RAKKTRFRSPEDLRE"
     PFAM_domain     complement(7507..8715)
                     /aSDomain="AA_permease_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13520.8"
                     /description="Amino acid permease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_137_0008"
                     /evalue="5.70E-40"
                     /label="ctg8_137"
                     /locus_tag="ctg8_137"
                     /protein_end="424"
                     /protein_start="21"
                     /score="137.6"
                     /tool="antismash"
                     /translation="LGFKLLLLFIVGDILGTGVYALTGDVAGEIGGAAWAPVLLAFAVA
                     TVTAFSYLELVTKYPQAAGAALYTHKAFGIHFVTFLVTFAVLSSGITSASTASKFLAEN
                     FIVGFNLDWGQFGVTMIAVVFLGLLAVINLRGVGESLKLNVVLTLIELTGLLIVILVGF
                     WAMAQGNVDFGRVMVFETSGDKTVFLALTAATSLAFFSMVGFEDSVNMAEETKDPVKTF
                     PKVMLTGLSITALVYVLVSIAAVAIVPVGRLEDSPTPLLEVVQVGAPGIPIDAIYPFMS
                     MFAVANTALINMMMASRLIYGMAKQDVLPRSLGKVLPGRRSPWSSIIFTTLIAFGLIIT
                     VTNFMGAETVSALGGTTALLLLAVFTVVNIAAIVLRRFPVDREHFRAPTVLPYIGALTC
                     AFLV"
     CDS             complement(9096..10904)
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     262.3; E-value: 5.7e-80)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 376.4; E-value:
                     4.1e-114)"
                     /gene_kind="transport"
                     /locus_tag="ctg8_138"
                     /transl_table=11
                     /translation="MSTYSGVQDEDNFLLDKGRSRQVRRRSLRLLGSMIRPVRAKFILT
                     IILVALSQAARVAGPAIIAFGIDHALPALRAGDNLPLVMAGAGYALAAVAVGVLTASYI
                     NATARLAQTMLLDLRRRVFRHTQRLSLEFHEKYTSGRIISRQTSDLEALRELLDNGVNS
                     LVSGAMYMTFTAISVFLMDWQTGLLIMLAALPMWFLTRWYQKRSQVAYRASRVASARLI
                     VHFIETMTGIRAVKAFRREKVNASRYEELAEDYRTVTVRSINLNGIFQPGLVLIGNVTV
                     ALVLLAGGFRVLDGGLEVGVLLALLLYTKRFFQPVDQMAMFYNSFQSASAALEKVSGLL
                     EEVPSVRAPKNPVALSGAAGHIKFDDVEFHYGDGPVVLPQMSLDIPAGQTIALVGQTGA
                     GKSTLAKLIARFYDVSSGQLTLDGVDLKDLSGTDLRRAVVMVTQEAFLFSGTVAENIAL
                     GNPGASQADIEAAATAVGADEFIRALPEGYDTDVNKRGGRVSSGQRQLISFARAFLADP
                     AVLILDEATSSLDIPSERLVQRGLQTLLGNRTALIIAHRLTTVKIADRVLVVHDGKVAE
                     DGTPDELIAGNGRFAALNQAWEDSLV"
     PFAM_domain     complement(9324..9767)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_138_0010"
                     /evalue="1.40E-30"
                     /label="ctg8_138"
                     /locus_tag="ctg8_138"
                     /protein_end="527"
                     /protein_start="379"
                     /score="106.7"
                     /tool="antismash"
                     /translation="QMSLDIPAGQTIALVGQTGAGKSTLAKLIARFYDVSSGQLTLDGV
                     DLKDLSGTDLRRAVVMVTQEAFLFSGTVAENIALGNPGASQADIEAAATAVGADEFIRA
                     LPEGYDTDVNKRGGRVSSGQRQLISFARAFLADPAVLILDEATS"
     PFAM_domain     complement(9957..10778)
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_138_0009"
                     /evalue="2.10E-41"
                     /label="ctg8_138"
                     /locus_tag="ctg8_138"
                     /protein_end="316"
                     /protein_start="42"
                     /score="142.5"
                     /tool="antismash"
                     /translation="ILTIILVALSQAARVAGPAIIAFGIDHALPALRAGDNLPLVMAGA
                     GYALAAVAVGVLTASYINATARLAQTMLLDLRRRVFRHTQRLSLEFHEKYTSGRIISRQ
                     TSDLEALRELLDNGVNSLVSGAMYMTFTAISVFLMDWQTGLLIMLAALPMWFLTRWYQK
                     RSQVAYRASRVASARLIVHFIETMTGIRAVKAFRREKVNASRYEELAEDYRTVTVRSIN
                     LNGIFQPGLVLIGNVTVALVLLAGGFRVLDGGLEVGVLLALLLYTKRFFQPV"
ORIGIN
        1 ctgccggcgt tcggaccttg ctggccaagt tcgggcttgg cgccgaccat gcgggccgga
       61 cttgtgacag tctgtcgatg ggggagaaga cccgtgccct gctggccgtc ctgcaggccc
      121 gggcagtgaa tttgctggtg ctggatgaac cgacgaacca tttggatgtt gaggccattg
      181 agcagctcga attggcgctc gcggccttcg acgggacact gttggtggtc agccatgacc
      241 ggacgctgct cgaaggcatt ggaatcactc aatggtggca gatggagcag tttctccgtt
      301 ccgaggataa ggatattgca ccgtgacacc ttcacgatgg agagagctcg caccgggtca
      361 acgagcgcaa ctcaccatcg tagacagggc ctccgtcgac gaggaccccg tcgacagcgg
      421 cccctccagc cgcgtggttt ttgaaactgc ggagtccgtg attgaggcgc cgaattggaa
      481 ccccggcggc gactggctgg tgttcaacag tgacgggctg ctctacagga tcaaggcaga
      541 cggatcgggg ccgccaatcc ggattccgac gggcgaactc aacgactcga ataacgatca
      601 cgttctgtcg ccggacggaa cctgtctctt cacgtcgtcc caaaacggtc atctgtaccg
      661 ggtgccggcc gatggcgggc cggcgcaacg cgtcagcgat gacgccgacg ggttgcaagc
      721 gcgatatctg cacggcatct cgcccgacgg aaccaccttg gctcttatcg gttgccatca
      781 acttcgggcg gcggaacgct tcaacatctt cacgttgtca ttgatcgatg gttccacccg
      841 tcagctcacg gactcggacc accatcacga cggggcggag tacagcccgg acggcgaatg
      901 gatctacttc aattctgacc gcgcatcgac ggcgaaaggg cactcgcaga tcttccgtat
      961 gcgtccggat gggcgggatc cgcagcagct gacatttgat acccgcgtca actggtttcc
     1021 ccacctgtca cccgacggca gttcgatggt ctacctgagt tatcaatcgt ctgtggtggg
     1081 gcatccggcc aataaggacg tgctgttacg acaggcggac ccggaaggag agagcgttcg
     1141 cactgtagcc ggtgtcttcg ggggccaggg aacaattaat gtcaacagct gggcgcccga
     1201 cagccaacgg tttgcctatg ttgcctatcc cgtccgcaac cgctgatgat gccggcgccg
     1261 ggcccgtcag ctcccggaac cgccgagact cccgcggcac ccccggcggc tgctatcttc
     1321 tggccacgga tgagcttctg cgcgtaggcc tcgaccaggc gtcgtcggga attccgaacc
     1381 gcaaatccat gacaaggagg gtaccggatc gaggagatgg aaaccatggc ataggcggtg
     1441 gtgctccacc gggcggtggt cgggcgaagg gtaacttccg gcgggtgaaa tcactactgc
     1501 cgtcacggga tttgacgagt tagtgcaccc taagtaaggg taggcttagc taacatagca
     1561 acgcatcccg tcggatgtgc ccgcctatca gtgacggaga tatttgtgtc gttgtcgtcc
     1621 tcgacggaag aagaaacgcg gttcgcagat caggtggaat cgacactttc cgccactaac
     1681 cagctgctca acagccgtac cgctccccac tacgccgccg aggtgatgtc cggcatccgg
     1741 gccgtatcgg cacaggtttc ggcgggtacg acgccctgca cgggaccgac gcctgaatcc
     1801 ctgcaccatg aggtgtccgc gatcgacctg gaccacccgt tgagcagtcc ggctgacgcg
     1861 ctggccgagg tcgaacgggt ctatctgcgc gatgccgtct atttccacga cgtgaagtac
     1921 gcggcccacc tgaactgccc ggtggcgatt cccgccctcg tcggcgaagc ggtgctttcc
     1981 gcagtcaata cgtccatgga cacctgggac cagagcaccg ccgccaccca catggaacag
     2041 cacctaatcc agtggacggc cgaacggctg ggtcttggcg acgatgcgga tggcgtcttc
     2101 accagcggtg gcagccagtc caacctgcag gcgctgctga tggcccggaa ccggttgcac
     2161 gcacggctgc ggtccgccca tcccgaccgg ccgccccgac tcgccgacgt gctgggcgga
     2221 ttccgcatct tcgcctccga tgtcagccac ttcagtgtcc aaaagtccgc ggccattctc
     2281 ggactgggac ccgaggcggt cgttgtggtg cccagcgacg gccagaagcg gatggacacc
     2341 gacgccctgg aacgcgaagt ggcccgctgc cgtcaggagg ggctgctgcc gatggccgtg
     2401 gtgggcaccg ccgggaccac ggatttcggc agtttcgatc cgctcgtccg gctcgcagat
     2461 atctgcgggg tcgaggacat ttggttgcac atcgacgcgg cctacggcgg cggacttatc
     2521 acgtcgcagc gtcaccggca cctgttggcc ggcaccggtg ccgcggattc ggtgactatc
     2581 gacttccaca agacgttctt ccagccggtc agctccagcg ccatcctggt ccgtgaccgc
     2641 gcccagctgg agcacgtcac ctactatgcg gattacctca atccgccggg cgggccgcca
     2701 aaccaggttg ataagagcct gcagaccacc cggcgcttcg acgcgctgaa actgtggctg
     2761 acgctgcgca ccatgggtgc agacgccgtc ggtgcgctgc tcgacgaggt gatcgagctg
     2821 gccaccggtt gcgcggggag cctgggcgcc atggaggatt tcgacgtcgt cgtccgccct
     2881 gcgttcagca ccgtggtgtt ccgctacctc ccgcccgggg ccccggatga aacggccgac
     2941 cgaatcaacc agcagatccg ctcggagcta ttcgactccg gcgaagcaat tatcggcggc
     3001 accatagtgg agggtcggca ctacctgaag ttcacgctgc tcaatgccga gaccaccatg
     3061 gcggacgtga aagaaatgat cgaactcatc cgccaacgcg gcagccacca cctggcatcg
     3121 gaggcgatgc accatggatg agccgtacga cttcatcggc atcggcctgg gccccttcaa
     3181 cctgggcctc gccgcactga ccgctcctat tacctgtctc aatgggctct tcctggaaca
     3241 ggaatcacac ttcgactggc accccggcat gatgctggac agcagcacgc tccaggtgcc
     3301 cttcatggcc gacctcgtca ccatggccga tcccacctcg gaattctcgt tcctgaactt
     3361 cctcaagagc accggccgca tctacccctt ctacatccgg gagcgcttca atccgctgcg
     3421 cgcggagtac aaccagtact gccagtgggt ggccggccga ctgcccatgc tgcggttcgg
     3481 cagcacagtg gattggattg agtacgacga cggcgcgcag gcttactcgg tgcggctcgc
     3541 caccggtgag cgtttccaag cccgccggct ggtgctcggc accggcaccc ggccggcggt
     3601 tccggaggtg tgcggcggtc tggagggacc agccctgcac agtgcggact acctgcaccg
     3661 ccgcgaagag ctgctgcagc gctccagcat taccgtcgtg ggcagcggcc aaagtgcggc
     3721 agagatctac ttcgacttgc tccaggaaat gggcggaggc gatttcgagc tgaactgggt
     3781 cacccgctcg ggccggttct tcccgctgga atacgcgaaa ctgacgctgg aaatgacctc
     3841 ccccgagtac tgcgcgtatt tccgctcgct gcccgagacg acccgcgacc ggctcaacgc
     3901 ggaccagcag aacctgtaca agggcatcga cgaatccttg atcaacgaaa tctacgattt
     3961 gctctaccag aaaagcctgc acgggccggt caataccaac ctgctgagca actccgactt
     4021 gcaggccgca cattgggacg gcgccgcgta cagcctcgaa ttcctccacc gggagcagga
     4081 ccgcagctac ggcctccgca cggaagccct ggtgctcgcc accggctacc agagcagcga
     4141 gccggacttc ctggccggcc tggagccgtg gctgaaccgg gatggccggg gccggctggc
     4201 ggccgacggt cactaccggg tcgatgcaga agcggggcat ggcgccattt acgtgcagaa
     4261 cgccgagctc aacacccacg gcttcgtcgc acccgacctg ggcatgggcg cgtaccggaa
     4321 ctcgtgcatc atccggaaca tgctcggctg ggaatactac ccggtggaat cgcgcattgg
     4381 tttccaacag ttcggggcgc cggtgcctga ccgggaagag cccttgcccg ccgtggaagg
     4441 ggcgccgctg tgaatttccc ccttcgcccg gtcgacccgg atgccgacgc caggctgctg
     4501 cacagctggt tcagccagga ctatgcctct ttctgggaca tgctggacgc cggggtcgac
     4561 gacgtgcggc gcgagcaccg ggccatagcc gcatctgacc atcaccacgc cttacttggg
     4621 ttcgacggcg gcgctccggt gttcctgatg gagcgctacg acccggcccg atcacccatc
     4681 gccggatgct acgaggcaac agcggccgac gtcggcatgc atctgctggt cgcgccgcca
     4741 gcggcgcccg tgccgggata cacccgctcc gtgatggccg ccgtgctgga ccacctcttc
     4801 gaggatccga cagtggagcg cgtcgtcgtc gaacccgaca tccgcaatca caagatccag
     4861 gcactcaacg acgcggccgg cttccggccg gtgacgaaca tcgaactgcc ggataagaca
     4921 gcagtgctca gcatctgcac ccgcaccgac tacgccgccg cacgaaacca gttggcgcgg
     4981 cgctcccagg aggctacagc gtgacaatta cggaactgga agaagtgcag gaacctgcgc
     5041 cgtccaccac ggtcgaccgc caggaacatc tcacagcgtg tgtctgggcc gaagccaacc
     5101 gccggttggt ggccaaggcc attgcagagt tctcccatga acggctgctg gccccggagc
     5161 aggcggacga gcagcgcttg ttccggatca ccagcgacga cggcggcacg gggtaccgct
     5221 tcgaggcaac ccggcgtgcg ttggaccatt gggacatcgc cggggacagt atccaacgcc
     5281 gccgcgacgg gcagaacctg gaacctgacg cgttggactt catgctcgaa ttccgcgggc
     5341 agctggggat tgccgaggac gtgcttcccg tctacctgga ggagatcagc agcaccctcg
     5401 ccggcgcggc ctacaaattg caaaaccccg ccccggactc agccgcactc gcacgggcag
     5461 gcggcacgcc cgcggccgct gcccaacgca tcgaacgggc catggccgag ggacatccct
     5521 gctttgtggc aaacaacggc cggttgggct tcggcgccgg cgattacagg gcgtacgcgc
     5581 cggaggccgg agccgccgtt cagctggtgt ggatcgccgt gcaccggagc cgggcagtct
     5641 tcacctccag ccgcaccctc ggcgaagcgg agctgtaccg gagcgaactc gggccgcaga
     5701 tgctggacgg ctttgccgcg cagctggcat cgcagggcct ggaggcccgc gactacctct
     5761 acatgccggt gcatccgtgg cagtgggaga acaagctgtc catcaccttc gccgccgaag
     5821 tcgcgcaccg gaacgtggtc tgcctcggtg ttggcgcgga ccgctaccag gcgcaacagt
     5881 ccatccgcac gttcttcaat ctggacgtgc cgcagcggtg ctacgtcaag acgtcactgt
     5941 ccgtgctgaa catgggattc atgcgcgggc tctccgcgga atatatgaag gcgacgccgg
     6001 ccatcaacga ctggcttcac cgactggtcg aagcggatga gaccctgcgg cggtccggct
     6061 tcaccgtgct gcgcgagttg gccgcagtcg gctatcacaa tgactactac gaagccgcga
     6121 cgacggcggg ctcaccgtac cggaagatgc tggcggccct gtggagggag agtccggccg
     6181 ggcagctgcg cgagggcgag cagctggcca ccatggcctc gctgctgcac cgcgaccgca
     6241 atggcgtccc gttcgtctcg gcgctgatgg cccaatccgg gctctcggcc aaggagtggc
     6301 tggagcacta cctgcgcgcg tatctgatgc cgctggtgca ttgcctctgt gcctatgacc
     6361 tggcgtttat gccccacggg gagaatatca tcctggtgct cgacgacggc gtcccggtcc
     6421 gggtgctgat gaaggacatt ggcgaggaaa tcgcggtgat cggcgacggg atcgaactgc
     6481 cggacgaagt cagccggatc agggtggacg ttccgtctga agagcaggtg ctgacgatct
     6541 tcaccgatgt cttcgattcg ttcttccgct tcctctccgc aatcctggcc ggcgacgggc
     6601 aactgtccga agacgctttc tggacggcgg tggcgaactg cctgcatcag taccgggacg
     6661 catcccccga aacggccgaa gcttttgacc gccatgagtt cttcgccgcc ggctttccgc
     6721 tgtcctgcct gaaccggctg cagctgagga acaaccggga aatgctcgac ctgaacgacc
     6781 cgtccgggtc actgcagcac gccgggcggg tggccaaccc catcgcccgt tttagcggtc
     6841 aggccgcatg aaatgtggcc gtcccgcccg ggcttcgccg gcgaaagttc aggagtagtc
     6901 ggccttcacc gccagcaccg ggcacggcgc ctccagcagg atccgttgtg cagtgctgcc
     6961 catgatcagc ttgcctaccg gcgtccggtg ccgcaggccg atcacgatca ggtcggcgtg
     7021 gtaccgctcg gccgaattga gcacttcttc accggcgtcg atatcgccca gctgttgcac
     7081 cagggtgtgt tcgacgccct cggtcttgag cctttcgtcc agggcggcgg attccgaatc
     7141 atccacgtag ttcttgtccg gatggctgct tcccctcgag gagttcacca cgatcaagtg
     7201 cacggcgcgc tgccgggcct cctcgactgc gcggttcaag gcggcggtgc cctcgggagt
     7261 ggggatatag ccgacgacga cgctcatagt tgctcctcta ttgttccgta ggtgcgttca
     7321 tgctgccgcc cgggtgctgc cgggtgccta tcggtgctac tctctgaggt cttcggggct
     7381 gcggaagcgg gtcttcttgg cgcgcactcc gcggttccag aaccaggtga tggcccacag
     7441 tacgaccccc agggcgagca tcaccccggc gatccggtac tcgatggggt cttgcgccca
     7501 cggaccaacc aggaaggcac aggtcagtgc cccaatgtag gggagcaccg tcggcgcgcg
     7561 gaaatgttcg cggtccaccg ggaagcggcg cagcacgatg gcggcgatgt tgaccacggt
     7621 gaacaccgcg agcagcagca aagccgtcgt tccgcccagc gcactgaccg tttcggcgcc
     7681 catgaagttg gtgacggtga tgatcagacc gaacgcgatc agcgtggtaa agatgatcga
     7741 gctccacggc gaccgccgtc ccggaagcac cttgcccagc gagcggggga ggacgtcctg
     7801 cttggccatc ccgtagatca ggcggctggc catcatcata ttgatcagcg ccgtattggc
     7861 tacggcgaac atcgacatga aggggtagat ggcgtcgatc gggattccgg gtgcgcccac
     7921 ctgcactacc tcgagcagcg gcgtcgggct atcctcgagg cggcccaccg gaacgatcgc
     7981 gacggcggca atggagacca gcacatagac cagtgcggta atactgagcc cggtgagcat
     8041 cactttcggg aacgtcttga ccgggtcttt ggtctcttcg gccatattca ccgagtcttc
     8101 gaacccgacc atggagaaga acgccagcga tgtagcagcc gtcagcgcga ggaacaccgt
     8161 tttgtcgccg gaggtctcga ataccatcac ccggccgaag tccacgttgc cttgggccat
     8221 cgcccagaag ccgacgagga tcacgatcag cagcccggtc agctcgatca gtgtcagcac
     8281 cacgttgagc ttgaggctct cgccgacacc tctcaggttg atcactgcca acaacccgag
     8341 gaagacgacg gcgatcatcg tcaccccgaa ttgcccccag tcgaggttga aaccaacaat
     8401 gaagttttcg gccaggaact tcgacgccgt tgaggccgag gtgatgcccg agctcaagac
     8461 cgcgaaggtg accaggaagg tcacgaagtg aataccgaac gccttgtggg tatacagcgc
     8521 ggcgccggcg gcctgcgggt atttagtcac cagttccagg taggagaagg cggtgacggt
     8581 ggcgacggcg aaggccagca gcaccggcgc ccatgccgca ccgccgattt cgccggccac
     8641 atcaccggtg agcgcgtaca cgccggtgcc gaggatgtcc ccgacaatga acagcagcag
     8701 cagcttgaag ccaagcgcct tcttcagctc cggctccggc tgcccgggtc cttgcttggt
     8761 gtctgtgggg ttgcccatca tcaactccgt ccggggaatc gtcgcatcat cgtcgcccag
     8821 aatatcatcg atagtaagct gcgttactat tattggcgga tgaggccacg acgcggcgga
     8881 tggtggagag tccgggcggc gccggtctcc gtcaaagccg gaacgggcac ctgatggtcg
     8941 gggtgacagg atttgaacct gcgacttcgt cgtcccgaac gacgcgcgct accaaactgc
     9001 gccacacccc gaaggtcgct gcgatcaacg caacctctca agaatagccg agattgcggc
     9061 caacttaaaa ctcgcgccaa acatgtgcgc agcgatcaga ccaaagagtc ctcccacgcc
     9121 tggttgagcg ctgcgaaccg gccgttaccg gcgatcaatt cgtccggggt tccgtcctcg
     9181 gccaccttgc cgtcgtggac caccaggacc cggtcggcga tcttcacggt ggtcagccgg
     9241 tgggcaataa tcagcgccgt ccggttgccc agcagagtct gcaggccgcg ctggaccagc
     9301 cgctcgctgg gaatatccag cgacgacgtc gcctcgtcca ggatcagcac cgccgggtcg
     9361 gccaggaacg cccgggcgaa ggaaatcagc tgccgctggc cggacgaaac ccggccacca
     9421 cgtttgttca catccgtgtc gtacccctcg ggcagggccc ggatgaattc atcggcgccc
     9481 accgccgtcg ccgccgcttc gatatcggcc tgcgacgctc ctggatttcc cagggcgata
     9541 ttctcggcga cggtgccgct gaacaggaag gcctcctggg tgaccatgac gacggcgcgg
     9601 cgcaggtcgg tgccggacag atccttcagg tcgaccccgt ccaaggtcag ttggccggag
     9661 gagacgtcgt agaagcgggc gatcagtttg gccagcgtcg acttgccggc cccggtctgc
     9721 ccgaccaggg cgatagtctg cccggcagga atgtccagcg acatttgagg cagcaccacc
     9781 ggaccgtctc cgtagtggaa ctcgacgtcg tcgaacttaa tgtgaccggc agcgccggac
     9841 agcgccactg gattcttcgg cgcccgcacg ctcggcactt cctccagcag tccggatacc
     9901 ttctccaagg cggccgaggc ggactggaag gagttgtaga acatggccat ctggtccacc
     9961 ggctggaaga agcgcttggt gtacagcagc agtgcgagca gcacgccgac ctcgaggccg
    10021 ccgtcgagca cccggaagcc gccggcgagc agcaccagag ccacagtgac gtttccgatc
    10081 agcaccagcc cgggctggaa gatgccgttc aggttgatgc tgcggactgt caccgtgcgg
    10141 tagtcctccg ccagctcctc ataccgtgag gcgttgacct tctcgcggcg gaacgccttg
    10201 accgcccgga tgccggtcat ggtttcgatg aagtgcacaa tcagccgtgc ggaggcgacc
    10261 cgggaggcgc ggtaggcgac ctgcgaccgc ttttggtacc agcgggtgag gaaccacatg
    10321 gggagggcgg cgagcatgat cagcagcccg gtctgccagt ccatcaggaa caccgaaatg
    10381 gccgtgaagg tcatgtacat cgccccggag acgagcgagt tgaccccgtt gtccagcagt
    10441 tcccgcagtg cctccagatc ggaggtctgc cgggagatga tccggcccga ggtgtacttc
    10501 tcgtggaact ccaggctgag ccgctgggta tggcggaaga cgcggcggcg caggtccagc
    10561 agcatggtct gggccagccg tgccgtggcg ttgatgtagc tggcggtgag cactccgacg
    10621 gcgaccgcgg cgagggcgta gcccgccccc gccatgacca ggggaagatt atcgcccgcg
    10681 cgcagggcag gcagcgcatg gtcgataccg aaggcgatga tcgccgggcc cgcgacccgc
    10741 gcagcctggg acagcgctac gaggatgatg gtcaggatga acttggcgcg gacgggccgg
    10801 atcatggagc cgagcaggcg cagcgaacga cgccggacct gccggctgcg gcccttgtcc
    10861 agcaggaagt tgtcctcgtc ctgcacgccg ctgtaggtac tcatgacagc acctcgtccg
    10921 ggtcctggcc ggccgtttct tcatcgtcca gactggtgat gatgtaccgg taatgttcgt
    10981 tggtggccag cagttgggcg tgagggccga cggcgttgat ggcgccgtgc tgcagcaccg
    11041 ccacccggtc ggcgagggcc actgtggagg aacggtgggc cacaatcaac gtggtggttc
    11101 cttccagtac ctggcgaagc cgttcggtga ccagttcctc ggttcccacg tccagggcgg
    11161 acaatgggtc atcgagcacc agcaccttgg gcttggcggc aatcgcgcgg gccagtgcga
    11221 tgcgctgccg ctgccccccg gagaggctga gtccttcctc gccgatcaag gtgtcgacgc
    11281 cgtcgggcag ttcgtaggcg aaatgcgcct gggcgacgtc gagggcttcg gcgagggcct
    11341 catcgccttg ttcgccggct ccgagcaaca cgttgtcccg caccgacgag gaaaacaggg
    11401 tggtgtcttc gaacgccacg gcgacatggg agcggatgtc cgacgtgctg aactgccgca
    11461 ggtccgtccc gtcaaacctg atactgccgc cggtgacgtc gtgcagcctg gcgacgagct
    11521 gcagcagggt gctcttgccg gagccggtga tgcccaccag ggccatggtt tcgccgggct
    11581 tcagggtcag gccgaccccg ttgagcaggt ccatgccggc ggccggggtg tcggggaact
    11641 tgaagtgcac gttgtcgaat tccacggcgc cgctcaggtg cttcaccggg cgggggtgtt
    11701 cgggctcggt gatgctgctg gtctcgtcca tcacctcgaa gtggcggtcg atggcggttt
    11761 ttgccgtcag cgtcatcgcc atcagcgggc caagcgattc caccggagca gccaccaccg
    11821 ctgccgtggc gaagaaggag accagggcgc c
//
