LOCUS       NC_010334.1            29757 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_010334.1 Shewanella halifaxensis HAW-EB4, complete sequence.
ACCESSION   NC_010334
VERSION     NC_010334.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:49:56
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3515437
            Orig. end    :: 3545194
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..29757
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[3525437:3535194]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..19757
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..29757
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..29757
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="5"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             291..1115
                     /NRPS_PKS="Domain: ECH (7-243). E-value: 2.9e-35. Score:
                     113.5. Matches aSDomain: nrpspksdomains_ctg1_2956_ECH.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 125.5; E-value:
                     3.3e-38)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2956"
                     /transl_table=11
                     /translation="MSKLSISHSEGIATVSINNPPSNVITSDLINEVNAFVLSLKYDRD
                     TKIVVFKSLHPLFFLAHLDLHVINGTTAGQAASIEFNHMITNIKAMKQLSVAVVDGVAR
                     GGGDEFVMACDLAYATENAAFAQPEIHVNIPTGGQGAVQYARRMGKNKALQALLLGNDF
                     TAQQAEALNIITQYVPKSEMDEFLAQVLGVIAQLEIRNILMYKEIIAASIIDEDAGAEL
                     ELRYFLERAKENKTQAIIDAFIKHGGQTDREAKDIQGIFVDTAAELAKSFNG"
     aSDomain        312..1019
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2956_ECH.1"
                     /evalue="2.90E-35"
                     /label="ctg1_2956_ECH.1"
                     /locus_tag="ctg1_2956"
                     /protein_end="243"
                     /protein_start="7"
                     /score="113.5"
                     /tool="antismash"
                     /translation="HSEGIATVSINNPPSNVITSDLINEVNAFVLSLKYDRDTKIVVFK
                     SLHPLFFLAHLDLHVINGTTAGQAASIEFNHMITNIKAMKQLSVAVVDGVARGGGDEFV
                     MACDLAYATENAAFAQPEIHVNIPTGGQGAVQYARRMGKNKALQALLLGNDFTAQQAEA
                     LNIITQYVPKSEMDEFLAQVLGVIAQLEIRNILMYKEIIAASIIDEDAGAELELRYFLE
                     RAKENKTQAIIDAF"
     PFAM_domain     315..1022
                     /aSDomain="ECH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00378.22"
                     /description="Enoyl-CoA hydratase/isomerase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2956_0098"
                     /evalue="8.40E-31"
                     /label="ctg1_2956"
                     /locus_tag="ctg1_2956"
                     /protein_end="244"
                     /protein_start="8"
                     /score="107.3"
                     /tool="antismash"
                     /translation="SEGIATVSINNPPSNVITSDLINEVNAFVLSLKYDRDTKIVVFKS
                     LHPLFFLAHLDLHVINGTTAGQAASIEFNHMITNIKAMKQLSVAVVDGVARGGGDEFVM
                     ACDLAYATENAAFAQPEIHVNIPTGGQGAVQYARRMGKNKALQALLLGNDFTAQQAEAL
                     NIITQYVPKSEMDEFLAQVLGVIAQLEIRNILMYKEIIAASIIDEDAGAELELRYFLER
                     AKENKTQAIIDAFI"
     CDS             1238..2128
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277:Radical SAM
                     domain protein (Score: 68.6; E-value: 7.1e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2957"
                     /sec_met_domain="PF04055 (E-value: 3.7e-13, bitscore: 48.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRYEGNIYRPPQEADAYILQCTIGCSYNKCTYCSMYKDVRYRARD
                     IGELIEDIQMAKRAYVTNIQKIEKVFLSDGDAISLPTSMLLEILAELYSAFPNLSHVST
                     YAGPQSTLSKTEEELTQLRQAGLTMTYLGVESGSDEVLSMIRKGVSAEEMLVAGRNIVA
                     SGIKLVAMVMIGIGGRGEISQTHIKETATLINQIKPYLLGTLTTVAIEGTVLYRQVAKG
                     EFNLLDPYEVLKEMKMLLEHIELPALYIDGTHASNLLPIKGLLKDDKLKMLASINKYLD
                     NKDESLIGKAYCGRF"
     PFAM_domain     1301..1771
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2957_0099"
                     /evalue="1.80E-12"
                     /label="ctg1_2957"
                     /locus_tag="ctg1_2957"
                     /protein_end="178"
                     /protein_start="21"
                     /score="48.0"
                     /tool="antismash"
                     /translation="TIGCSYNKCTYCSMYKDVRYRARDIGELIEDIQMAKRAYVTNIQK
                     IEKVFLSDGDAISLPTSMLLEILAELYSAFPNLSHVSTYAGPQSTLSKTEEELTQLRQA
                     GLTMTYLGVESGSDEVLSMIRKGVSAEEMLVAGRNIVASGIKLVAMVMIGIGG"
     CDS             complement(2272..2994)
                     /locus_tag="ctg1_2958"
                     /transl_table=11
                     /translation="MELYLDAIKEIKELANAEEIHRVDDVSIYLERFTDLDLIATGIYA
                     EVYEVPGEPDKVIKLCNSKIDGYYLFARWCMRPENQDNPHVPTIHREDTVELSSGRVVR
                     FYVMERLEDITDDGTEPTRPSHFHDDDFGKLWGTLRTMTLPFADPQKPFTDEVSSVDEF
                     VEQIQEPRAHFYMSSDERKPVVIDDEIIDEHEELLKTLFKVLSFIDDHGVMDLHGGNYM
                     LRGDTIVITDPISHKYAG"
     CDS             complement(3139..3732)
                     /locus_tag="ctg1_2959"
                     /transl_table=11
                     /translation="LTIKIDFEQQIKHWLLEDEYRFNALRIVEQLKLNDWMLAAGFVRN
                     LVWDKLHGLQTALNDIDLIYFDSSDLSAERDTAIEAELNRIAPIYPWSVKNQARMHLRN
                     QHQAYTSSLDAMSYWPEKQTAVAVSSRLLTFKSLAASTAIIEPASLILHSPFDLACLFD
                     LSLQHNPKAKRALFERRVKQKRWLQSYPKLRDNG"
     PFAM_domain     complement(3151..3654)
                     /aSDomain="NTP_transf_6"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06042.13"
                     /description="Nucleotidyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2959_0100"
                     /evalue="1.40E-52"
                     /label="ctg1_2959"
                     /locus_tag="ctg1_2959"
                     /protein_end="194"
                     /protein_start="26"
                     /score="177.9"
                     /tool="antismash"
                     /translation="IVEQLKLNDWMLAAGFVRNLVWDKLHGLQTALNDIDLIYFDSSDL
                     SAERDTAIEAELNRIAPIYPWSVKNQARMHLRNQHQAYTSSLDAMSYWPEKQTAVAVSS
                     RLLTFKSLAASTAIIEPASLILHSPFDLACLFDLSLQHNPKAKRALFERRVKQKRWLQS
                     YPKLR"
     CDS             complement(3878..4279)
                     /locus_tag="ctg1_2960"
                     /transl_table=11
                     /translation="MISLLKKSVVLLCMLVLTACVTVEDKPPVVVNGAAGYLEKLPLPQ
                     GSSITIAIIDLDTPGVIVAQKSFNIVRAPVPFKFLLPADSIDDSIHYGVVAMIQYQGKV
                     IFQTYDRFPVINNNKYTTEVLMKAVPAPR"
     PFAM_domain     complement(3905..4195)
                     /aSDomain="YscW"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09619.12"
                     /description="Type III secretion system lipoprotein
                     chaperone (YscW)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2960_0101"
                     /evalue="2.70E-16"
                     /label="ctg1_2960"
                     /locus_tag="ctg1_2960"
                     /protein_end="125"
                     /protein_start="28"
                     /score="59.9"
                     /tool="antismash"
                     /translation="VVVNGAAGYLEKLPLPQGSSITIAIIDLDTPGVIVAQKSFNIVRA
                     PVPFKFLLPADSIDDSIHYGVVAMIQYQGKVIFQTYDRFPVINNNKYTTEVL"
     CDS             complement(4323..5189)
                     /locus_tag="ctg1_2961"
                     /transl_table=11
                     /translation="MSQVLDDLLALLSLERIEVGLFRGQSQDLGFGHVFGGQVMGQALS
                     AAKQTVSPDRKVHSLHSYFLRAGDEKLPIVYDVEIMRDGGSFSARRVKAIQKGRPIFYM
                     TCSFQTAEEGYDHQAVMPDVPGPDGLLNQQELAMTLRDKVPSKVLEKFMADTPIEMRLV
                     NPSDPIAPAAREPIRHVWIRANGKVPDNMSVHDYLLAYASDFNFLVTAAQPHGVSFLTP
                     GMRMATIDHAMWFHRPFDLSQWLLYTIDSPNASGGRGFVRGQFFNQQGELVASATQEGL
                     IRMMKTS"
     aSDomain        complement(4341..5156)
                     /aSDomain="TIGR00189"
                     /aSTool="tigrfam"
                     /description="tesB: acyl-CoA thioesterase II"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2961_0020"
                     /evalue="3.70E-91"
                     /identifier="TIGR00189"
                     /label="ctg1_2961"
                     /locus_tag="ctg1_2961"
                     /protein_end="283"
                     /protein_start="11"
                     /score="303.4"
                     /tool="antismash"
                     /translation="LSLERIEVGLFRGQSQDLGFGHVFGGQVMGQALSAAKQTVSPDRK
                     VHSLHSYFLRAGDEKLPIVYDVEIMRDGGSFSARRVKAIQKGRPIFYMTCSFQTAEEGY
                     DHQAVMPDVPGPDGLLNQQELAMTLRDKVPSKVLEKFMADTPIEMRLVNPSDPIAPAAR
                     EPIRHVWIRANGKVPDNMSVHDYLLAYASDFNFLVTAAQPHGVSFLTPGMRMATIDHAM
                     WFHRPFDLSQWLLYTIDSPNASGGRGFVRGQFFNQQGELVASATQEGLIR"
     PFAM_domain     complement(4344..5096)
                     /aSDomain="4HBT_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13622.8"
                     /description="Thioesterase-like superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2961_0102"
                     /evalue="1.20E-59"
                     /label="ctg1_2961"
                     /locus_tag="ctg1_2961"
                     /protein_end="282"
                     /protein_start="31"
                     /score="202.8"
                     /tool="antismash"
                     /translation="GHVFGGQVMGQALSAAKQTVSPDRKVHSLHSYFLRAGDEKLPIVY
                     DVEIMRDGGSFSARRVKAIQKGRPIFYMTCSFQTAEEGYDHQAVMPDVPGPDGLLNQQE
                     LAMTLRDKVPSKVLEKFMADTPIEMRLVNPSDPIAPAAREPIRHVWIRANGKVPDNMSV
                     HDYLLAYASDFNFLVTAAQPHGVSFLTPGMRMATIDHAMWFHRPFDLSQWLLYTIDSPN
                     ASGGRGFVRGQFFNQQGELVASATQEGLI"
     CDS             complement(5270..6298)
                     /NRPS_PKS="Domain: PKS_KR (38-224). E-value: 1.6e-16.
                     Score: 52.6. Matches aSDomain:
                     nrpspksdomains_ctg1_2962_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     163.3; E-value: 1.2e-49)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2962"
                     /sec_met_domain="adh_short (E-value: 1.5e-30, bitscore:
                     104.5, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSCNCRFRNETAFLAVNVYICDRQICLGVETMRFEGQVAIVTGA
                     ASGLGRAYAIALAERGARVVLVDNETTQTKDVSSSMTNLEPDSGLQACGAAITALGGEF
                     KSFTLDVTSIDDINSMVDDVVKSWGRVDILINNAGIHKSCAFEQMSASSWKHNLDVDLN
                     GTFYMTQAVWPFMKRQSYGRVVMSSASSIYGDMYETSFSTSKMAVMGLVNSLHLEGAEH
                     GIKVNSIIPHAVTSMTAEHLAPTVRPLFSKTTVTATMLYLCSSKSPSGEHLLAAAGGIS
                     HAALVEFSPGRFKAEECTPEVITERWPELYHAKPVTAHRSGEAQVLAWAKASANQRRIV
                     LE"
     PFAM_domain     complement(5579..6034)
                     /aSDomain="adh_short"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00106.27"
                     /description="short chain dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2962_0104"
                     /evalue="1.50E-34"
                     /label="ctg1_2962"
                     /locus_tag="ctg1_2962"
                     /protein_end="240"
                     /protein_start="88"
                     /score="119.2"
                     /tool="antismash"
                     /translation="GLQACGAAITALGGEFKSFTLDVTSIDDINSMVDDVVKSWGRVDI
                     LINNAGIHKSCAFEQMSASSWKHNLDVDLNGTFYMTQAVWPFMKRQSYGRVVMSSASSI
                     YGDMYETSFSTSKMAVMGLVNSLHLEGAEHGIKVNSIIPHAVTSMTAE"
     aSDomain        complement(5627..6184)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2962_PKS_KR.1"
                     /evalue="1.60E-16"
                     /label="ctg1_2962_PKS_KR.1"
                     /locus_tag="ctg1_2962"
                     /protein_end="224"
                     /protein_start="38"
                     /score="52.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAIVTGAASGLGRAYAIALAERGARVVLVDNETTQTKDVSSSMTN
                     LEPDSGLQACGAAITALGGEFKSFTLDVTSIDDINSMVDDVVKSWGRVDILINNAGIHK
                     SCAFEQMSASSWKHNLDVDLNGTFYMTQAVWPFMKRQSYGRVVMSSASSIYGDMYETSF
                     STSKMAVMGLVNSLHLEGAEHGI"
     PFAM_domain     complement(6047..6187)
                     /aSDomain="adh_short"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00106.27"
                     /description="short chain dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2962_0103"
                     /evalue="6.20E-08"
                     /label="ctg1_2962"
                     /locus_tag="ctg1_2962"
                     /protein_end="84"
                     /protein_start="37"
                     /score="32.4"
                     /tool="antismash"
                     /translation="QVAIVTGAASGLGRAYAIALAERGARVVLVDNETTQTKDVSSSMT
                     NL"
     CDS_motif       complement(6101..6178)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_2962_0001"
                     /evalue="1.10E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg1_2962"
                     /protein_end="66"
                     /protein_start="40"
                     /score="18.1"
                     /tool="antismash"
                     /translation="IVTGAASGLGRAYAIALAERGARVVL"
     CDS             6540..7430
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2963"
                     /sec_met_domain="ubiA (E-value: 1.3e-22, bitscore: 78.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPWILAIRPRTLPAAIGPLLVGNVLALQLEQFSFFIAVISMLCA
                     LLLQIAVNLANDYFDFKSGVDTEERLGPVRVTQSGMLSPMAVRNAMILCLVLALIVGSL
                     LIYHGGLPIAFLAVAAILGALGYSGGPYPLASHGLGEVAAFVFFGLVAVVGSYFLQAGE
                     TATSAWLLGSAIGFLNAAIMLVNNTRDMETDIKAGKKTLAVRMGLAQSRIFYQSFLYLP
                     FAIIFAGFLMGALPGLPVLLAGLAFVMARSLSNDFNEVTGAALNPLLGRTAKLTMIFSA
                     LFSIGLLGDIYLFVT"
     aSDomain        6564..7397
                     /aSDomain="TIGR00751"
                     /aSTool="tigrfam"
                     /description="menA: 1,4-dihydroxy-2-naphthoate
                     octaprenyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2963_0021"
                     /evalue="1.50E-57"
                     /identifier="TIGR00751"
                     /label="ctg1_2963"
                     /locus_tag="ctg1_2963"
                     /protein_end="286"
                     /protein_start="8"
                     /score="193.2"
                     /tool="antismash"
                     /translation="RPRTLPAAIGPLLVGNVLALQLEQFSFFIAVISMLCALLLQIAVN
                     LANDYFDFKSGVDTEERLGPVRVTQSGMLSPMAVRNAMILCLVLALIVGSLLIYHGGLP
                     IAFLAVAAILGALGYSGGPYPLASHGLGEVAAFVFFGLVAVVGSYFLQAGETATSAWLL
                     GSAIGFLNAAIMLVNNTRDMETDIKAGKKTLAVRMGLAQSRIFYQSFLYLPFAIIFAGF
                     LMGALPGLPVLLAGLAFVMARSLSNDFNEVTGAALNPLLGRTAKLTMIFSALFSIG"
     PFAM_domain     6588..7292
                     /aSDomain="UbiA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01040.20"
                     /description="UbiA prenyltransferase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2963_0105"
                     /evalue="1.70E-35"
                     /label="ctg1_2963"
                     /locus_tag="ctg1_2963"
                     /protein_end="251"
                     /protein_start="16"
                     /score="122.7"
                     /tool="antismash"
                     /translation="IGPLLVGNVLALQLEQFSFFIAVISMLCALLLQIAVNLANDYFDF
                     KSGVDTEERLGPVRVTQSGMLSPMAVRNAMILCLVLALIVGSLLIYHGGLPIAFLAVAA
                     ILGALGYSGGPYPLASHGLGEVAAFVFFGLVAVVGSYFLQAGETATSAWLLGSAIGFLN
                     AAIMLVNNTRDMETDIKAGKKTLAVRMGLAQSRIFYQSFLYLPFAIIFAGFLMGALPGL
                     PVLLAGLAFVMAR"
     CDS             complement(7522..9069)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100:3-hydroxyisobutyrate dehydrogenase (Score: 14.2;
                     E-value: 0.00039)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2964"
                     /transl_table=11
                     /translation="MKNQSNLYDIGVIGLGVMGKNLALNIADNQYRVAAFDLDELKVQD
                     TVAQEELERKRYLKQITEPRIEGCNNLSEMLSKLEKPRVLLLSVPAGAPVDGVCQSLIE
                     AGIENDDIVIDTGNSLWTDTVEREKRYADNFLFFSCAVSGGEVGARFGPSLMPSGSLKA
                     WNRIEPIWQAIAAKVDAKTGLPIERFEPGNPVKEGEPCTTYIGPAGSGHYVKMVHNGIE
                     YADMQLICEAYQLLNQGLGLSPSEVGDVFERWDQGILNSYLMQISADVLKQADPLTGAP
                     LVDMILDKAGQKGTGLWTAVSSLQIGCPAPTIAEAVYARAVSTQKAQRQQLSQQLSGPS
                     EALLATINRGEKQTFIAQLENALYCAKVSCYAQGFQLMAMQAKEQAWQLDFAEIAKIWR
                     AGCIIRATFLQSITKAYQQDSELENLLMADSFAKALSEKQQDWREAVSQAVLSGIPAPC
                     ISSALAYYDSYRCETLPASLLQGQRDFFGAHTFERTDKPAGEKYHLNWSGDRSLHKM"
     aSDomain        complement(7549..9045)
                     /aSDomain="TIGR00873"
                     /aSTool="tigrfam"
                     /description="gnd: 6-phosphogluconate dehydrogenase
                     (decarboxylating)"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2964_0022"
                     /evalue="1.50E-174"
                     /identifier="TIGR00873"
                     /label="ctg1_2964"
                     /locus_tag="ctg1_2964"
                     /protein_end="507"
                     /protein_start="8"
                     /score="579.2"
                     /tool="antismash"
                     /translation="DIGVIGLGVMGKNLALNIADNQYRVAAFDLDELKVQDTVAQEELE
                     RKRYLKQITEPRIEGCNNLSEMLSKLEKPRVLLLSVPAGAPVDGVCQSLIEAGIENDDI
                     VIDTGNSLWTDTVEREKRYADNFLFFSCAVSGGEVGARFGPSLMPSGSLKAWNRIEPIW
                     QAIAAKVDAKTGLPIERFEPGNPVKEGEPCTTYIGPAGSGHYVKMVHNGIEYADMQLIC
                     EAYQLLNQGLGLSPSEVGDVFERWDQGILNSYLMQISADVLKQADPLTGAPLVDMILDK
                     AGQKGTGLWTAVSSLQIGCPAPTIAEAVYARAVSTQKAQRQQLSQQLSGPSEALLATIN
                     RGEKQTFIAQLENALYCAKVSCYAQGFQLMAMQAKEQAWQLDFAEIAKIWRAGCIIRAT
                     FLQSITKAYQQDSELENLLMADSFAKALSEKQQDWREAVSQAVLSGIPAPCISSALAYY
                     DSYRCETLPASLLQGQRDFFGAHTFERTDKPAGEKYHLNWS"
     PFAM_domain     complement(7552..8439)
                     /aSDomain="6PGD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00393.21"
                     /description="6-phosphogluconate dehydrogenase, C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2964_0107"
                     /evalue="3.20E-124"
                     /label="ctg1_2964"
                     /locus_tag="ctg1_2964"
                     /protein_end="506"
                     /protein_start="210"
                     /score="414.1"
                     /tool="antismash"
                     /translation="GHYVKMVHNGIEYADMQLICEAYQLLNQGLGLSPSEVGDVFERWD
                     QGILNSYLMQISADVLKQADPLTGAPLVDMILDKAGQKGTGLWTAVSSLQIGCPAPTIA
                     EAVYARAVSTQKAQRQQLSQQLSGPSEALLATINRGEKQTFIAQLENALYCAKVSCYAQ
                     GFQLMAMQAKEQAWQLDFAEIAKIWRAGCIIRATFLQSITKAYQQDSELENLLMADSFA
                     KALSEKQQDWREAVSQAVLSGIPAPCISSALAYYDSYRCETLPASLLQGQRDFFGAHTF
                     ERTDKPAGEKYHLNW"
     PFAM_domain     complement(8533..9045)
                     /aSDomain="NAD_binding_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03446.17"
                     /description="NAD binding domain of 6-phosphogluconate
                     dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2964_0106"
                     /evalue="3.60E-35"
                     /label="ctg1_2964"
                     /locus_tag="ctg1_2964"
                     /protein_end="179"
                     /protein_start="8"
                     /score="121.6"
                     /tool="antismash"
                     /translation="DIGVIGLGVMGKNLALNIADNQYRVAAFDLDELKVQDTVAQEELE
                     RKRYLKQITEPRIEGCNNLSEMLSKLEKPRVLLLSVPAGAPVDGVCQSLIEAGIENDDI
                     VIDTGNSLWTDTVEREKRYADNFLFFSCAVSGGEVGARFGPSLMPSGSLKAWNRIEPIW
                     QAIAAKVD"
     CDS             complement(10001..11905)
                     /NRPS_PKS="Domain: AMP-binding (65-502). E-value: 1.1e-86.
                     Score: 282.8. Matches aSDomain:
                     nrpspksdomains_ctg1_2965_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     277.2; E-value: 3.5e-84)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2965"
                     /sec_met_domain="AMP-binding (E-value: 2.6e-93, bitscore:
                     310.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKNKNKQLHAKSINQPEAFWAEAASQIDWFSPWNNVLDDSEAPFY
                     HWFKGGKLNTCYNAVDRHVDAGRGDQIALQYVSPVTDVEYGISYRELLAQVSRLAGYMD
                     SIGVKKGDRVVIYMPMVPETAFAMLACARIGAIHSVVFGGFAANELATRINDAKPKLIL
                     SASCGIEPSGIIPYKPLLDAALDQATHKVDHCLVLNRGQLEAELFPGRDIDWQAAVAAA
                     PNIDCQPLDATDPLYILYTSGTTGQPKGVVRDNGGHAVALAWSMKHIYDINAGDVFWAA
                     SDVGWVVGHSYIVYGPLLVGATSILYEGKPIGTPDPGAFWRTIAKYRVKSFFTAPTAIR
                     AIKRDDPHGDYLEGVDLSCLKNVFLAGERCDPDTLHWTEGKLKKPVIDHWWQTETGWPV
                     AANLMGYAPVEIKAGSPALAVPGYQIEVVDVMGDEVEANESGNVVIKLPLPPGTLTTLW
                     QNEQRYQDSYLSMYPGYYLTGDAGYKDEDGYLYIMSRIDDIINVAGHRLSTGRFEEVLC
                     QHEAVAEAAVIGVKDVLKGQVPLGLVVLKKGVSLNDDDLNQQLMSLVRQEIGPVASFRL
                     VSAVQKLPKTRSGKILRGTMRNIADNQSYNVPATIEDPATLDIVRNTLTRMGYADAHV"
     PFAM_domain     complement(10136..10372)
                     /aSDomain="AMP-binding_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13193.8"
                     /description="AMP-binding enzyme C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2965_0110"
                     /evalue="1.50E-20"
                     /label="ctg1_2965"
                     /locus_tag="ctg1_2965"
                     /protein_end="590"
                     /protein_start="511"
                     /score="74.1"
                     /tool="antismash"
                     /translation="FEEVLCQHEAVAEAAVIGVKDVLKGQVPLGLVVLKKGVSLNDDDL
                     NQQLMSLVRQEIGPVASFRLVSAVQKLPKTRSGK"
     aSDomain        complement(10400..11710)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2965_AMP-binding.1"
                     /evalue="1.10E-86"
                     /label="ctg1_2965_AMP-binding.1"
                     /locus_tag="ctg1_2965"
                     /protein_end="502"
                     /protein_start="65"
                     /score="282.8"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="AGRGDQIALQYVSPVTDVEYGISYRELLAQVSRLAGYMDSIGVKK
                     GDRVVIYMPMVPETAFAMLACARIGAIHSVVFGGFAANELATRINDAKPKLILSASCGI
                     EPSGIIPYKPLLDAALDQATHKVDHCLVLNRGQLEAELFPGRDIDWQAAVAAAPNIDCQ
                     PLDATDPLYILYTSGTTGQPKGVVRDNGGHAVALAWSMKHIYDINAGDVFWAASDVGWV
                     VGHSYIVYGPLLVGATSILYEGKPIGTPDPGAFWRTIAKYRVKSFFTAPTAIRAIKRDD
                     PHGDYLEGVDLSCLKNVFLAGERCDPDTLHWTEGKLKKPVIDHWWQTETGWPVAANLMG
                     YAPVEIKAGSPALAVPGYQIEVVDVMGDEVEANESGNVVIKLPLPPGTLTTLWQNEQRY
                     QDSYLSMYPGYYLTGDAGYKDEDGYLYIMSRIDDIINV"
     PFAM_domain     complement(10400..11710)
                     /aSDomain="AMP-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00501.30"
                     /description="AMP-binding enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2965_0109"
                     /evalue="7.90E-81"
                     /label="ctg1_2965"
                     /locus_tag="ctg1_2965"
                     /protein_end="502"
                     /protein_start="65"
                     /score="271.9"
                     /tool="antismash"
                     /translation="AGRGDQIALQYVSPVTDVEYGISYRELLAQVSRLAGYMDSIGVKK
                     GDRVVIYMPMVPETAFAMLACARIGAIHSVVFGGFAANELATRINDAKPKLILSASCGI
                     EPSGIIPYKPLLDAALDQATHKVDHCLVLNRGQLEAELFPGRDIDWQAAVAAAPNIDCQ
                     PLDATDPLYILYTSGTTGQPKGVVRDNGGHAVALAWSMKHIYDINAGDVFWAASDVGWV
                     VGHSYIVYGPLLVGATSILYEGKPIGTPDPGAFWRTIAKYRVKSFFTAPTAIRAIKRDD
                     PHGDYLEGVDLSCLKNVFLAGERCDPDTLHWTEGKLKKPVIDHWWQTETGWPVAANLMG
                     YAPVEIKAGSPALAVPGYQIEVVDVMGDEVEANESGNVVIKLPLPPGTLTTLWQNEQRY
                     QDSYLSMYPGYYLTGDAGYKDEDGYLYIMSRIDDIINV"
     CDS_motif       complement(11150..11197)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_2965_0001"
                     /evalue="8.00E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg1_2965"
                     /protein_end="252"
                     /protein_start="236"
                     /score="24.6"
                     /tool="antismash"
                     /translation="YILYTSGTTGQPKGVV"
     PFAM_domain     complement(11729..11890)
                     /aSDomain="ACAS_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16177.7"
                     /description="Acetyl-coenzyme A synthetase N-terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2965_0108"
                     /evalue="1.00E-22"
                     /label="ctg1_2965"
                     /locus_tag="ctg1_2965"
                     /protein_end="59"
                     /protein_start="5"
                     /score="79.9"
                     /tool="antismash"
                     /translation="KQLHAKSINQPEAFWAEAASQIDWFSPWNNVLDDSEAPFYHWFKG
                     GKLNTCYNA"
     CDS             12270..12668
                     /gene_functions="regulatory (smcogs)
                     SMCOG1171:transcriptional regulator, MerR family (Score:
                     74.8; E-value: 1.9e-22)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2966"
                     /transl_table=11
                     /translation="MVEKPLSQTTYSISDLSKEFDITTRSIRFYEDQGLLKPKRRGQTR
                     VYSLKDRVRLKLILRGKRLGFSLAETRRLFELYDADKNSSGQLHTMLELVEEKKVSLQQ
                     QMDDIKVVLMELNSAEQQCLEALENNAQ"
     PFAM_domain     12300..12497
                     /aSDomain="MerR_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13411.8"
                     /description="MerR HTH family regulatory protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2966_0111"
                     /evalue="1.10E-15"
                     /label="ctg1_2966"
                     /locus_tag="ctg1_2966"
                     /protein_end="76"
                     /protein_start="10"
                     /score="57.6"
                     /tool="antismash"
                     /translation="YSISDLSKEFDITTRSIRFYEDQGLLKPKRRGQTRVYSLKDRVRL
                     KLILRGKRLGFSLAETRRLFE"
     CDS             12767..13936
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 369.6; E-value:
                     3e-112)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2967"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 6.2e-36, bitscore:
                     121.5, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 7.4e-28, bitscore:
                     94.7, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 4.3e-42, bitscore:
                     141.9, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQLYTSLNFGLGEEVDMLRDAVQSFAANKIAPIAAKTDLDNAFP
                     NELWPVLGDMGLLGVTVSEEYGGAEMGYLAHVVAMEEISRASASIGLSYGAHSNLCVNQ
                     INRNGNSEQKAKYLPKLITGEHIGALAMSEPNAGSDVVSMKLHARKEGDRYILNGNKMW
                     ITNGPDAHTYVIYAKTDLDKGAHGITAFIVERGSKGFSTAQKLDKLGMRGSNTCELVFE
                     DCEVPEENILGGLNNGVKVLMSGLDYERVVLSGGPLGIMTACMDIVVPYIHEREQFGKS
                     IGQFQLVQGKLADMYTGMNAAKSYIYNVAKSCDRGETTRKDAAGAILYSAELATKMALD
                     AIQLLGGNGYVNEYATGRLLRDAKLYEIGAGTSEIRRMLIGRELFNESK"
     PFAM_domain     12806..13141
                     /aSDomain="Acyl-CoA_dh_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02771.18"
                     /description="Acyl-CoA dehydrogenase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2967_0112"
                     /evalue="9.30E-36"
                     /label="ctg1_2967"
                     /locus_tag="ctg1_2967"
                     /protein_end="125"
                     /protein_start="13"
                     /score="123.0"
                     /tool="antismash"
                     /translation="EEVDMLRDAVQSFAANKIAPIAAKTDLDNAFPNELWPVLGDMGLL
                     GVTVSEEYGGAEMGYLAHVVAMEEISRASASIGLSYGAHSNLCVNQINRNGNSEQKAKY
                     LPKLITGE"
     PFAM_domain     13151..13438
                     /aSDomain="Acyl-CoA_dh_M"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02770.21"
                     /description="Acyl-CoA dehydrogenase, middle domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2967_0113"
                     /evalue="2.20E-27"
                     /label="ctg1_2967"
                     /locus_tag="ctg1_2967"
                     /protein_end="224"
                     /protein_start="128"
                     /score="95.1"
                     /tool="antismash"
                     /translation="ALAMSEPNAGSDVVSMKLHARKEGDRYILNGNKMWITNGPDAHTY
                     VIYAKTDLDKGAHGITAFIVERGSKGFSTAQKLDKLGMRGSNTCELVFEDC"
     PFAM_domain     13472..13918
                     /aSDomain="Acyl-CoA_dh_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00441.26"
                     /description="Acyl-CoA dehydrogenase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2967_0114"
                     /evalue="1.90E-41"
                     /label="ctg1_2967"
                     /locus_tag="ctg1_2967"
                     /protein_end="384"
                     /protein_start="235"
                     /score="141.9"
                     /tool="antismash"
                     /translation="NNGVKVLMSGLDYERVVLSGGPLGIMTACMDIVVPYIHEREQFGK
                     SIGQFQLVQGKLADMYTGMNAAKSYIYNVAKSCDRGETTRKDAAGAILYSAELATKMAL
                     DAIQLLGGNGYVNEYATGRLLRDAKLYEIGAGTSEIRRMLIGREL"
     CDS             14024..15631
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase,
                     (Score: 509.6; E-value: 1.7e-154)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2968"
                     /transl_table=11
                     /translation="VTQLSSRINARSDEFKAKFDDMATVVQDLKLKLQQIEQGGGDVAR
                     SRHLSRGKLLPRQRVEKLLDPGSPFLEISQFAAFELYEDVVPAAGVIAGIGRVSGVECM
                     IIANDATVKGGTYYPVTVKKHLRAQEIASRCHLPCIYLVDSGGANLPRQDEVFPDRDHF
                     GRIFYNQAQMSAKGIPQIAVVMGLCTAGGAYVPAMADESIIVKEQGTIFLAGPPLVKAA
                     TGEEVTAEELGGAEVHTKISGVADHMAQNDEHALELARKAVTRLNHQKQIAAQLSPVKP
                     PLFDINELYGIVGTDLKKPFDVKEVIARLVDDSDFDEFKANYGNTLVCGFARIHGYPVG
                     IVANNGILFSESAQKGAHFIELCCQRKIPLLFLQNITGFMVGKKYEHEGIAKHGAKMVT
                     AVSCANVPKFTVIIGGSYGAGNYGMCGRAFEPTMMWMWPNARISVMGGEQAAGVLATVK
                     RDGLARKGVEWSNDEEQAFRQPIVEQYDKEGHPYHASARLWDDGIIDPAQTRDVVGLAL
                     SAALNAPIEETKFGVFRM"
     PFAM_domain     14165..15601
                     /aSDomain="Carboxyl_trans"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01039.24"
                     /description="Carboxyl transferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2968_0115"
                     /evalue="1.60E-158"
                     /label="ctg1_2968"
                     /locus_tag="ctg1_2968"
                     /protein_end="526"
                     /protein_start="47"
                     /score="528.5"
                     /tool="antismash"
                     /translation="HLSRGKLLPRQRVEKLLDPGSPFLEISQFAAFELYEDVVPAAGVI
                     AGIGRVSGVECMIIANDATVKGGTYYPVTVKKHLRAQEIASRCHLPCIYLVDSGGANLP
                     RQDEVFPDRDHFGRIFYNQAQMSAKGIPQIAVVMGLCTAGGAYVPAMADESIIVKEQGT
                     IFLAGPPLVKAATGEEVTAEELGGAEVHTKISGVADHMAQNDEHALELARKAVTRLNHQ
                     KQIAAQLSPVKPPLFDINELYGIVGTDLKKPFDVKEVIARLVDDSDFDEFKANYGNTLV
                     CGFARIHGYPVGIVANNGILFSESAQKGAHFIELCCQRKIPLLFLQNITGFMVGKKYEH
                     EGIAKHGAKMVTAVSCANVPKFTVIIGGSYGAGNYGMCGRAFEPTMMWMWPNARISVMG
                     GEQAAGVLATVKRDGLARKGVEWSNDEEQAFRQPIVEQYDKEGHPYHASARLWDDGIID
                     PAQTRDVVGLALSAALNAPIE"
     CDS             15690..16571
                     /NRPS_PKS="Domain: ECH (22-233). E-value: 5.1e-43. Score:
                     138.9. Matches aSDomain: nrpspksdomains_ctg1_2969_ECH.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 191.6; E-value:
                     2.1e-58)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2969"
                     /transl_table=11
                     /translation="MNNSITTDTERLTQQLQYVSCTLDGGVAQMVLDRADKHNAFDEVM
                     ISEMIKVLEHFSANVQCQVLVIKANGKNFSAGADLNWMRKQAKMDFGQNLSDANELAKL
                     MSLLDKFPKPTIALVQGAAFGGALGLICCSDIAIANQRASFCLSEVKLGLIPAVISPYV
                     TRAMGQRAARRYMLTAERFDVQKALELQVIHEVNDDLDAAAQPMIDALLCNSPLGMTWV
                     KTLLLSLEDGVIDQNTLDYTSERIARIRVSEEGQEGLNAFFEKRSPQWPATTDFNAATK
                     NNNQSASGQGAK"
     aSDomain        15756..16388
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2969_ECH.1"
                     /evalue="5.10E-43"
                     /label="ctg1_2969_ECH.1"
                     /locus_tag="ctg1_2969"
                     /protein_end="233"
                     /protein_start="22"
                     /score="138.9"
                     /tool="antismash"
                     /translation="LDGGVAQMVLDRADKHNAFDEVMISEMIKVLEHFSANVQCQVLVI
                     KANGKNFSAGADLNWMRKQAKMDFGQNLSDANELAKLMSLLDKFPKPTIALVQGAAFGG
                     ALGLICCSDIAIANQRASFCLSEVKLGLIPAVISPYVTRAMGQRAARRYMLTAERFDVQ
                     KALELQVIHEVNDDLDAAAQPMIDALLCNSPLGMTWVKTLLLSLEDGV"
     PFAM_domain     15762..16499
                     /aSDomain="ECH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00378.22"
                     /description="Enoyl-CoA hydratase/isomerase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2969_0116"
                     /evalue="1.90E-43"
                     /label="ctg1_2969"
                     /locus_tag="ctg1_2969"
                     /protein_end="270"
                     /protein_start="24"
                     /score="148.7"
                     /tool="antismash"
                     /translation="GGVAQMVLDRADKHNAFDEVMISEMIKVLEHFSANVQCQVLVIKA
                     NGKNFSAGADLNWMRKQAKMDFGQNLSDANELAKLMSLLDKFPKPTIALVQGAAFGGAL
                     GLICCSDIAIANQRASFCLSEVKLGLIPAVISPYVTRAMGQRAARRYMLTAERFDVQKA
                     LELQVIHEVNDDLDAAAQPMIDALLCNSPLGMTWVKTLLLSLEDGVIDQNTLDYTSERI
                     ARIRVSEEGQEGLNAFFEKRSPQW"
     PFAM_domain     16573..16902
                     /aSDomain="Biotin_carb_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00289.24"
                     /description="Biotin carboxylase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2970_0117"
                     /evalue="3.00E-42"
                     /label="ctg1_2970"
                     /locus_tag="ctg1_2970"
                     /protein_end="110"
                     /protein_start="0"
                     /score="143.7"
                     /tool="antismash"
                     /translation="MFTKLLIANRGEIACRIINTAKVMGVRTVALYSDADIDARHVAMA
                     DEAFYLGGSAPADSYLKGELIIEIAKRAGAEAIHPGYGFLSENADFALKCEQANIAFVG
                     PSAAAI"
     CDS             16573..18681
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090:acetyl-CoA carboxylase biotin carboxylase (Score:
                     680.3; E-value: 5.2e-206)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2970"
                     /sec_met_domain="ATP-grasp (E-value: 4.9e-06, bitscore:
                     24.2, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFTKLLIANRGEIACRIINTAKVMGVRTVALYSDADIDARHVAMA
                     DEAFYLGGSAPADSYLKGELIIEIAKRAGAEAIHPGYGFLSENADFALKCEQANIAFVG
                     PSAAAIDSMGSKSAAKEIMGAANVPLVPGYHGDAQNDELLVSEANKMGFPLLIKAAFGG
                     GGKGMRIVESNNEVLDAIHSARREAISSFGNDKLLMERYLRQPRHVEVQVFADSHGNCI
                     YLSDRDCSIQRRHQKVVEEAPAPGLSDALRVKMGEAAVAAAKAINYEGAGTVEFLLDTD
                     DSFYFMEMNTRLQVEHPVTELVTGQDLVKWQLMVASGSPLPLKQNEVRIVGHAFEARIY
                     AEDPHNDFLPASGKLDFLREPEQSQFVRIDSGVRENDVISNFYDPMISKLITWDESRPR
                     ALQRLVHALDDYQISGLKHNIEFLANIAKHQAFSDANFSTDFIERYGDALLTAQSNATP
                     STRRDTALAIAALYQLCARKKQAKNDTLTSHDPYSPWGKVSGFRLNSASQHQVALLDDN
                     HEINHLELIETQVAGKPQYQLQLSDNLLTLSGELIDEILHAEIVQHKLGDSQAEQASKA
                     NGHKIKLPVSQVGNDFTLFINSKSYHYRALESEEIEEQDNLEDKLKAPMNGTIVTQLVS
                     VGDVVKAGQGIMVMEAMKMEYTIESPFDGVVSAFFFEPGELVSDGMLLAEVVAEVEAEV
                     NPEKEEAG"
     PFAM_domain     16918..17538
                     /aSDomain="CPSase_L_D2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02786.19"
                     /description="Carbamoyl-phosphate synthase L chain, ATP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2970_0118"
                     /evalue="3.00E-77"
                     /label="ctg1_2970"
                     /locus_tag="ctg1_2970"
                     /protein_end="322"
                     /protein_start="115"
                     /score="259.0"
                     /tool="antismash"
                     /translation="KSAAKEIMGAANVPLVPGYHGDAQNDELLVSEANKMGFPLLIKAA
                     FGGGGKGMRIVESNNEVLDAIHSARREAISSFGNDKLLMERYLRQPRHVEVQVFADSHG
                     NCIYLSDRDCSIQRRHQKVVEEAPAPGLSDALRVKMGEAAVAAAKAINYEGAGTVEFLL
                     DTDDSFYFMEMNTRLQVEHPVTELVTGQDLVKWQLMVASGSPLP"
     PFAM_domain     17578..17904
                     /aSDomain="Biotin_carb_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02785.21"
                     /description="Biotin carboxylase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2970_0119"
                     /evalue="1.60E-36"
                     /label="ctg1_2970"
                     /locus_tag="ctg1_2970"
                     /protein_end="444"
                     /protein_start="335"
                     /score="124.8"
                     /tool="antismash"
                     /translation="EARIYAEDPHNDFLPASGKLDFLREPEQSQFVRIDSGVRENDVIS
                     NFYDPMISKLITWDESRPRALQRLVHALDDYQISGLKHNIEFLANIAKHQAFSDANFST
                     DFIER"
     PFAM_domain     18430..18627
                     /aSDomain="Biotin_lipoyl"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00364.24"
                     /description="Biotin-requiring enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2970_0120"
                     /evalue="2.60E-15"
                     /label="ctg1_2970"
                     /locus_tag="ctg1_2970"
                     /protein_end="685"
                     /protein_start="619"
                     /score="56.1"
                     /tool="antismash"
                     /translation="KLKAPMNGTIVTQLVSVGDVVKAGQGIMVMEAMKMEYTIESPFDG
                     VVSAFFFEPGELVSDGMLLAE"
     CDS             18678..18857
                     /locus_tag="ctg1_2971"
                     /transl_table=11
                     /translation="MKMTNVINAIESPFDGVVGAFFFEPGELVSDGMLLAEVEAKVETA
                     ELEPTETVAAEESA"
     CDS             18858..19757
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 228.9;
                     E-value: 2.1e-69)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2972"
                     /sec_met_domain="HMGL-like (E-value: 7.5e-59, bitscore:
                     197.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAISYPQQVSIFEVGARDGLQNEKPVTTQDKIVLIEDLATAGVKR
                     IEAASFVSPKWVPQMADSADVLVGITRHKGVTYSALTPNLKGLELALEAGADEVAIFGA
                     ASESFSQKNINCSIEESIERFIPVMELAKAKNVPVRGYVSCTLGCPYEGEIAVSEVARV
                     SELLYQMGCYEISLGDTIGVGTPLNARRMVEAVAEVVPKDKLALHFHDTYGQALANILA
                     CLETGVSVIDSSVAGLGGCPYAKGASGNLATEDLVYMLHGLGIETGIDLTKLVNAGNKI
                     SHALGRQSGSKVARALSE"
     PFAM_domain     18882..19694
                     /aSDomain="HMGL-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00682.21"
                     /description="HMGL-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2972_0121"
                     /evalue="4.90E-59"
                     /label="ctg1_2972"
                     /locus_tag="ctg1_2972"
                     /protein_end="279"
                     /protein_start="8"
                     /score="200.1"
                     /tool="antismash"
                     /translation="VSIFEVGARDGLQNEKPVTTQDKIVLIEDLATAGVKRIEAASFVS
                     PKWVPQMADSADVLVGITRHKGVTYSALTPNLKGLELALEAGADEVAIFGAASESFSQK
                     NINCSIEESIERFIPVMELAKAKNVPVRGYVSCTLGCPYEGEIAVSEVARVSELLYQMG
                     CYEISLGDTIGVGTPLNARRMVEAVAEVVPKDKLALHFHDTYGQALANILACLETGVSV
                     IDSSVAGLGGCPYAKGASGNLATEDLVYMLHGLGIETGIDLTKLVNAGN"
     CDS             19829..20593
                     /locus_tag="ctg1_2973"
                     /transl_table=11
                     /translation="MAGLNKEPNQGLNKVVTSYEEALKGLTNNMTVMVGGFGLCGIPEG
                     LIAQMVKTGVTGLTAISNNAGVDDFGLGLLLKSRQIDTMIASYVGENATFEQQMLSGEL
                     NVILTPQGTLAEKIRAGGAGIPAFFTATGYGTPVAEGKETREIDGRHYVLEPALKADFA
                     LVRAWKADTMGNLVFRKTAANFNPMMATAGKITVVEAEHIVQPGELDPDHIHTPGIYVN
                     RVIQGKFEKRIEQRTVKPDSKSRAESRTDEKA"
     aSDomain        19862..20506
                     /aSDomain="TIGR02429"
                     /aSTool="tigrfam"
                     /description="pcaI_scoA_fam: 3-oxoacid CoA-transferase, A
                     subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2973_0023"
                     /evalue="5.30E-77"
                     /identifier="TIGR02429"
                     /label="ctg1_2973"
                     /locus_tag="ctg1_2973"
                     /protein_end="226"
                     /protein_start="11"
                     /score="256.0"
                     /tool="antismash"
                     /translation="LNKVVTSYEEALKGLTNNMTVMVGGFGLCGIPEGLIAQMVKTGVT
                     GLTAISNNAGVDDFGLGLLLKSRQIDTMIASYVGENATFEQQMLSGELNVILTPQGTLA
                     EKIRAGGAGIPAFFTATGYGTPVAEGKETREIDGRHYVLEPALKADFALVRAWKADTMG
                     NLVFRKTAANFNPMMATAGKITVVEAEHIVQPGELDPDHIHTPGIYVNRVIQ"
     PFAM_domain     19877..20506
                     /aSDomain="CoA_trans"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01144.25"
                     /description="Coenzyme A transferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2973_0122"
                     /evalue="4.80E-75"
                     /label="ctg1_2973"
                     /locus_tag="ctg1_2973"
                     /protein_end="226"
                     /protein_start="16"
                     /score="251.8"
                     /tool="antismash"
                     /translation="TSYEEALKGLTNNMTVMVGGFGLCGIPEGLIAQMVKTGVTGLTAI
                     SNNAGVDDFGLGLLLKSRQIDTMIASYVGENATFEQQMLSGELNVILTPQGTLAEKIRA
                     GGAGIPAFFTATGYGTPVAEGKETREIDGRHYVLEPALKADFALVRAWKADTMGNLVFR
                     KTAANFNPMMATAGKITVVEAEHIVQPGELDPDHIHTPGIYVNRVIQ"
     CDS             20606..21262
                     /locus_tag="ctg1_2974"
                     /transl_table=11
                     /translation="MALSREQLAQRVAQELQDGFYVNLGIGIPTLVANYIPEGIDVMLQ
                     SENGLLGMGEFPTEETIDADLINAGKQTVTAVDGASFFSSAESFAMIRGGHVDLTVLGA
                     FEVDEQGSIASWMIPGKLIKGMGGAMDLVAGADNIIVTMMHADKKGNSKLLPKCELPLT
                     GYGCIKRVLTDLAFMEIKDGAFHLLERAPGVSVEEIISKTAGKLVVPEYVPEMSF"
     aSDomain        20615..21229
                     /aSDomain="TIGR02428"
                     /aSTool="tigrfam"
                     /description="pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B
                     subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2974_0024"
                     /evalue="3.60E-97"
                     /identifier="TIGR02428"
                     /label="ctg1_2974"
                     /locus_tag="ctg1_2974"
                     /protein_end="208"
                     /protein_start="3"
                     /score="321.7"
                     /tool="antismash"
                     /translation="SREQLAQRVAQELQDGFYVNLGIGIPTLVANYIPEGIDVMLQSEN
                     GLLGMGEFPTEETIDADLINAGKQTVTAVDGASFFSSAESFAMIRGGHVDLTVLGAFEV
                     DEQGSIASWMIPGKLIKGMGGAMDLVAGADNIIVTMMHADKKGNSKLLPKCELPLTGYG
                     CIKRVLTDLAFMEIKDGAFHLLERAPGVSVEEIISKTAGKLV"
     PFAM_domain     20621..21205
                     /aSDomain="CoA_trans"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01144.25"
                     /description="Coenzyme A transferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2974_0123"
                     /evalue="5.80E-40"
                     /label="ctg1_2974"
                     /locus_tag="ctg1_2974"
                     /protein_end="200"
                     /protein_start="5"
                     /score="137.1"
                     /tool="antismash"
                     /translation="EQLAQRVAQELQDGFYVNLGIGIPTLVANYIPEGIDVMLQSENGL
                     LGMGEFPTEETIDADLINAGKQTVTAVDGASFFSSAESFAMIRGGHVDLTVLGAFEVDE
                     QGSIASWMIPGKLIKGMGGAMDLVAGADNIIVTMMHADKKGNSKLLPKCELPLTGYGCI
                     KRVLTDLAFMEIKDGAFHLLERAPGVSVEEII"
     CDS             complement(21374..24487)
                     /gene_functions="resistance (resist) RND_efflux (Score:
                     963.2; E-value: 1.2e-291)"
                     /gene_functions="transport (smcogs)
                     SMCOG1049:AcrB/AcrD/AcrF family protein (Score: 1047.2;
                     E-value: 0)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_2975"
                     /transl_table=11
                     /translation="VSYFFISRPVFAWVIAILISIAGVIAIPKLAVERFPSVAPPSIGL
                     YLSYPGASPQTINDSVVTLIEREISGINGLLYFSSSSDASGSASITVTFENGTDPEMAQ
                     VEIQNKIRAIEPRLPLAVRQIGITVETTSSNNLMYLGLISPSGEYSEQQLSDYMVRNIV
                     EEIKRVPGVGRVQMYGAEFAMRIWVDPVALTGYNLTMEDVTSAIAEQNVQISPGKVGDS
                     PTSGGQMTVHSLTAQGQLETPEQFRAIVLRSNIDAGMVQLGDVAKVELGAQNYLFSNRE
                     NGQQSTSAAIQLSPGANAIATSQGIRDRLAELKLAMPSNMDYSITSDAAIFAKISIQKV
                     VVTLLEAMVLVFLVMYLFLQKIRYTLIPAIVAPIALLGTFAVMWLMGFSINVFTMFGMV
                     LAIGIIVDDAIVVVENVERVMAETGLPPKAATEQAMKSIYSAVIGITAVLSAVFIPMAF
                     ASGSVGTIFQQFSLAMAVSILFSAFLALTLTPALCATLLKPLTEHDHKSGGFFGWFNRN
                     FHNFTQKVTAGVAHLVKRTGRVMALYIVLVVACIYSFTLVPSTFLPEEDQGYYMTSIQL
                     PPDATVERTMDVVSKIEAFTLGREAIDASMSVLGFSFSGTGPGSAFGITTLKDWQLRGG
                     SSTQQEVAALSDYLSDLTEGEVFSVLPAAIDGLGNSSNLSFQLQDSGNAGYERFQLIQK
                     EFLEQAYASEKLSSVFYEALPETSGIHLNIDRAKARALGVPFNAISDTISTAMGSNYVN
                     DFPNNGRLQQVIVQVQAESRMQLEDILQLAIRNEQGGTVYLSEFVTPVWQMAPQQLTRF
                     NGLLAVAVSASPAPGYSTGEAMQEVERIAASLPTAAGIEWTGLSLQEKQAESQTVWLLL
                     FSMLVIFLVLAALYESWSIPLAVILVVPLGIIGAVGFVLLNGVANDVFFKVGLVTIIGL
                     SAKNAILIVEFAKQAQAEGICLVDSVLQATKQRLRPILMTSLAFSCGIIPLYLATGPSS
                     EIQNSIGTGVLGGMFTGTVFAVLFVPVFFVFICQLLERVRPKLGVTLN"
     aSDomain        complement(21404..24484)
                     /aSDomain="TIGR00915"
                     /aSTool="tigrfam"
                     /description="2A0602: RND transporter,
                     hydrophobe/amphiphile efflux-1 (HAE1) family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2975_0025"
                     /evalue="0.00E+00"
                     /identifier="TIGR00915"
                     /label="ctg1_2975"
                     /locus_tag="ctg1_2975"
                     /protein_end="1028"
                     /protein_start="1"
                     /score="1309.6"
                     /tool="antismash"
                     /translation="SYFFISRPVFAWVIAILISIAGVIAIPKLAVERFPSVAPPSIGLY
                     LSYPGASPQTINDSVVTLIEREISGINGLLYFSSSSDASGSASITVTFENGTDPEMAQV
                     EIQNKIRAIEPRLPLAVRQIGITVETTSSNNLMYLGLISPSGEYSEQQLSDYMVRNIVE
                     EIKRVPGVGRVQMYGAEFAMRIWVDPVALTGYNLTMEDVTSAIAEQNVQISPGKVGDSP
                     TSGGQMTVHSLTAQGQLETPEQFRAIVLRSNIDAGMVQLGDVAKVELGAQNYLFSNREN
                     GQQSTSAAIQLSPGANAIATSQGIRDRLAELKLAMPSNMDYSITSDAAIFAKISIQKVV
                     VTLLEAMVLVFLVMYLFLQKIRYTLIPAIVAPIALLGTFAVMWLMGFSINVFTMFGMVL
                     AIGIIVDDAIVVVENVERVMAETGLPPKAATEQAMKSIYSAVIGITAVLSAVFIPMAFA
                     SGSVGTIFQQFSLAMAVSILFSAFLALTLTPALCATLLKPLTEHDHKSGGFFGWFNRNF
                     HNFTQKVTAGVAHLVKRTGRVMALYIVLVVACIYSFTLVPSTFLPEEDQGYYMTSIQLP
                     PDATVERTMDVVSKIEAFTLGREAIDASMSVLGFSFSGTGPGSAFGITTLKDWQLRGGS
                     STQQEVAALSDYLSDLTEGEVFSVLPAAIDGLGNSSNLSFQLQDSGNAGYERFQLIQKE
                     FLEQAYASEKLSSVFYEALPETSGIHLNIDRAKARALGVPFNAISDTISTAMGSNYVND
                     FPNNGRLQQVIVQVQAESRMQLEDILQLAIRNEQGGTVYLSEFVTPVWQMAPQQLTRFN
                     GLLAVAVSASPAPGYSTGEAMQEVERIAASLPTAAGIEWTGLSLQEKQAESQTVWLLLF
                     SMLVIFLVLAALYESWSIPLAVILVVPLGIIGAVGFVLLNGVANDVFFKVGLVTIIGLS
                     AKNAILIVEFAKQAQAEGICLVDSVLQATKQRLRPILMTSLAFSCGIIPLYLATGPSSE
                     IQNSIGTGVLGGMFTGTVFAVLFVPVFFVFICQLLERV"
     PFAM_domain     complement(21425..24484)
                     /aSDomain="ACR_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00873.21"
                     /description="AcrB/AcrD/AcrF family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2975_0124"
                     /evalue="0.00E+00"
                     /label="ctg1_2975"
                     /locus_tag="ctg1_2975"
                     /protein_end="1021"
                     /protein_start="1"
                     /score="1088.9"
                     /tool="antismash"
                     /translation="SYFFISRPVFAWVIAILISIAGVIAIPKLAVERFPSVAPPSIGLY
                     LSYPGASPQTINDSVVTLIEREISGINGLLYFSSSSDASGSASITVTFENGTDPEMAQV
                     EIQNKIRAIEPRLPLAVRQIGITVETTSSNNLMYLGLISPSGEYSEQQLSDYMVRNIVE
                     EIKRVPGVGRVQMYGAEFAMRIWVDPVALTGYNLTMEDVTSAIAEQNVQISPGKVGDSP
                     TSGGQMTVHSLTAQGQLETPEQFRAIVLRSNIDAGMVQLGDVAKVELGAQNYLFSNREN
                     GQQSTSAAIQLSPGANAIATSQGIRDRLAELKLAMPSNMDYSITSDAAIFAKISIQKVV
                     VTLLEAMVLVFLVMYLFLQKIRYTLIPAIVAPIALLGTFAVMWLMGFSINVFTMFGMVL
                     AIGIIVDDAIVVVENVERVMAETGLPPKAATEQAMKSIYSAVIGITAVLSAVFIPMAFA
                     SGSVGTIFQQFSLAMAVSILFSAFLALTLTPALCATLLKPLTEHDHKSGGFFGWFNRNF
                     HNFTQKVTAGVAHLVKRTGRVMALYIVLVVACIYSFTLVPSTFLPEEDQGYYMTSIQLP
                     PDATVERTMDVVSKIEAFTLGREAIDASMSVLGFSFSGTGPGSAFGITTLKDWQLRGGS
                     STQQEVAALSDYLSDLTEGEVFSVLPAAIDGLGNSSNLSFQLQDSGNAGYERFQLIQKE
                     FLEQAYASEKLSSVFYEALPETSGIHLNIDRAKARALGVPFNAISDTISTAMGSNYVND
                     FPNNGRLQQVIVQVQAESRMQLEDILQLAIRNEQGGTVYLSEFVTPVWQMAPQQLTRFN
                     GLLAVAVSASPAPGYSTGEAMQEVERIAASLPTAAGIEWTGLSLQEKQAESQTVWLLLF
                     SMLVIFLVLAALYESWSIPLAVILVVPLGIIGAVGFVLLNGVANDVFFKVGLVTIIGLS
                     AKNAILIVEFAKQAQAEGICLVDSVLQATKQRLRPILMTSLAFSCGIIPLYLATGPSSE
                     IQNSIGTGVLGGMFTGTVFAVLFVPVFFVFI"
     CDS             complement(24521..25657)
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 156.3; E-value:
                     1.7e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_2976"
                     /transl_table=11
                     /translation="MASEFKKITRLGLFAAVCFWTTACEKSSTDEAFNYPNTANIATIT
                     AELTQVTLFDELQGRVRPLRSAEIRPQVEGIITQRLFKQGDTLKQGDALFQIDQDIFTI
                     DVEIKQAALEQSMAHLALIQSQVDRFTQLDRTKAVSKQAFEEVSFNLQIAAATVQQNRA
                     QLKHSELQLEYAKVTAPISGIIGEALVTEGSLVSRTEPQPLAIIQQIDKVYIDVRQPAS
                     KLGLLRRLLANEQKNSEQGVKVIVQSSAESADDIEGQILFSGISVDENTGDLIIRIIAD
                     NAQQKLLPGMYVRTQIPRQKLQAITVPEHAVRRNSAGLPFVYIVVNDKFELRPVQLEGL
                     QQRRYVISKGVNPNDIVVVTGQDNLREGAELVLSDWQQ"
     aSDomain        complement(24548..25531)
                     /aSDomain="TIGR01730"
                     /aSTool="tigrfam"
                     /description="RND_mfp: efflux transporter, RND family, MFP
                     subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2976_0026"
                     /evalue="1.10E-65"
                     /identifier="TIGR01730"
                     /label="ctg1_2976"
                     /locus_tag="ctg1_2976"
                     /protein_end="370"
                     /protein_start="42"
                     /score="219.7"
                     /tool="antismash"
                     /translation="TITAELTQVTLFDELQGRVRPLRSAEIRPQVEGIITQRLFKQGDT
                     LKQGDALFQIDQDIFTIDVEIKQAALEQSMAHLALIQSQVDRFTQLDRTKAVSKQAFEE
                     VSFNLQIAAATVQQNRAQLKHSELQLEYAKVTAPISGIIGEALVTEGSLVSRTEPQPLA
                     IIQQIDKVYIDVRQPASKLGLLRRLLANEQKNSEQGVKVIVQSSAESADDIEGQILFSG
                     ISVDENTGDLIIRIIADNAQQKLLPGMYVRTQIPRQKLQAITVPEHAVRRNSAGLPFVY
                     IVVNDKFELRPVQLEGLQQRRYVISKGVNPNDIVVVTGQDNLREGAE"
     PFAM_domain     complement(24779..25270)
                     /aSDomain="HlyD_D23"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16576.7"
                     /description="Barrel-sandwich domain of CusB or HlyD
                     membrane-fusion"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2976_0126"
                     /evalue="2.60E-11"
                     /label="ctg1_2976"
                     /locus_tag="ctg1_2976"
                     /protein_end="293"
                     /protein_start="129"
                     /score="43.3"
                     /tool="antismash"
                     /translation="FTQLDRTKAVSKQAFEEVSFNLQIAAATVQQNRAQLKHSELQLEY
                     AKVTAPISGIIGEALVTEGSLVSRTEPQPLAIIQQIDKVYIDVRQPASKLGLLRRLLAN
                     EQKNSEQGVKVIVQSSAESADDIEGQILFSGISVDENTGDLIIRIIADNAQQKLLPGMY
                     V"
     PFAM_domain     complement(25358..25462)
                     /aSDomain="Biotin_lipoyl_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13533.8"
                     /description="Biotin-lipoyl like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2976_0125"
                     /evalue="1.90E-05"
                     /label="ctg1_2976"
                     /locus_tag="ctg1_2976"
                     /protein_end="100"
                     /protein_start="65"
                     /score="24.4"
                     /tool="antismash"
                     /translation="SAEIRPQVEGIITQRLFKQGDTLKQGDALFQIDQD"
     CDS             25912..26589
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 157; E-value: 8.7e-48)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2977"
                     /transl_table=11
                     /translation="MIRVLLIEDDRDLAETLLQLMELAQMLPDHVSNGIAGLTLARSNS
                     YDVLVIDVGLPKLDGYSVCKQLRASGIDTPILFLTAFSSIDNKLEGFASGGDDYLAKPF
                     DNRELIARITALSGRKSSHVKRLEIAGLIMNCEQQQVSYQGQKLELTPACYTLLEVLMR
                     ASPEIVSRQSLENKLWGDEPPSSNVLKAHIYYLRRALTQVQLAEMLYTSTGRGWALRPS
                     NTR"
     PFAM_domain     25921..26250
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2977_0127"
                     /evalue="3.70E-22"
                     /label="ctg1_2977"
                     /locus_tag="ctg1_2977"
                     /protein_end="113"
                     /protein_start="3"
                     /score="78.7"
                     /tool="antismash"
                     /translation="VLLIEDDRDLAETLLQLMELAQMLPDHVSNGIAGLTLARSNSYDV
                     LVIDVGLPKLDGYSVCKQLRASGIDTPILFLTAFSSIDNKLEGFASGGDDYLAKPFDNR
                     ELIARI"
     PFAM_domain     26344..26565
                     /aSDomain="Trans_reg_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00486.30"
                     /description="Transcriptional regulatory protein, C
                     terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2977_0128"
                     /evalue="4.70E-16"
                     /label="ctg1_2977"
                     /locus_tag="ctg1_2977"
                     /protein_end="218"
                     /protein_start="144"
                     /score="58.7"
                     /tool="antismash"
                     /translation="GQKLELTPACYTLLEVLMRASPEIVSRQSLENKLWGDEPPSSNVL
                     KAHIYYLRRALTQVQLAEMLYTSTGRGWA"
     CDS             26586..27875
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 74.4; E-value: 1.6e-22)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2978"
                     /transl_table=11
                     /translation="MKLRQSLSALLLGGAGFILLLLVLSYTLWARENYFRALDTSFSVS
                     MHKAQELINQQGFDSIAPGLAIIDAQLFRQYKALPESIKLTFSENQLQVGQHYYADGIT
                     QSDKAKHRDFFIYTAEHKEQGIYYLVQQYEDSDSHSHWDIADDQLQQIWVVSVIVTLLL
                     VIVILACFRYLAKPIYRLNAWSKQLNSTDLNKPIPSFEYQELDRLAEQILNSLREVDSV
                     YQRESQFLQYASHELRTPITVVKSNAALLEQLISPSNMPPLQRIIRASNTMHHLTETLL
                     WLTRKELAQPKACQFQLDSLINELVEEHDYLLNGKNVELQVRIAAQAVVLPQILVRIVA
                     ANLIRNAMQHIDEGVINIALGKEELTIENNGVILSDNTPHGANSDGFGLGLKLIHQISE
                     QQGWSFSTSSKPQRYIASIGFSSKNNLMTQ"
     PFAM_domain     27264..27446
                     /aSDomain="HisKA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00512.27"
                     /description="His Kinase A (phospho-acceptor) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2978_0129"
                     /evalue="5.00E-11"
                     /label="ctg1_2978"
                     /locus_tag="ctg1_2978"
                     /protein_end="287"
                     /protein_start="226"
                     /score="42.6"
                     /tool="antismash"
                     /translation="SQFLQYASHELRTPITVVKSNAALLEQLISPSNMPPLQRIIRASN
                     TMHHLTETLLWLTRKE"
     CDS             27908..28378
                     /locus_tag="ctg1_2979"
                     /transl_table=11
                     /translation="MIERISKAYDGEIYGISFFSYFDKNYQLTASSKTLWETLIQVETL
                     TADLIEPTLNSHQVQYDSNNALMINKGSKDAQKWCHLPWAELVETLVNWVEPYEKKYRC
                     WADEARIETDTFRLIADHETAIYECFKAEKVGISGETILLEFIRKYEPKRSS"
     CDS             complement(28468..29469)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2980"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.5e-19, bitscore:
                     69.5, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.4e-11, bitscore: 42.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VDKVFLDVLNFIFISAAIYFSIASICIVFGKRSKRSSTQNNLAFD
                     ELASDKSATDYTKLPQLKSYQTRDGKRLPYRHYDAKSDKVVVFLHGSGWHSQYLFPLTD
                     FLSSEGLAQVYTPDLRGHGQAPERRGDVDYIDQLEDDLADFIELIKTEHPDCKLIVAGH
                     SSGGGLAVRFAGSRYGKRVDAYVLLSPYLKYNAPIMRPNSGGWAAPHTLRIVGLTMLNN
                     IGIHQFDYVIAIDFNMPQEFRNGTETLSYTHRLNTAFAPRNYKQDLCAITQPLLVLVGT
                     ADEAFIAEQFEPVFSQYTSAQVTLLPDVTHMGVVVNPAVRPILRQWFENLHV"
     PFAM_domain     complement(28558..29229)
                     /aSDomain="Hydrolase_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12146.10"
                     /description="Serine aminopeptidase, S33"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2980_0130"
                     /evalue="1.40E-28"
                     /label="ctg1_2980"
                     /locus_tag="ctg1_2980"
                     /protein_end="304"
                     /protein_start="80"
                     /score="99.9"
                     /tool="antismash"
                     /translation="KSDKVVVFLHGSGWHSQYLFPLTDFLSSEGLAQVYTPDLRGHGQA
                     PERRGDVDYIDQLEDDLADFIELIKTEHPDCKLIVAGHSSGGGLAVRFAGSRYGKRVDA
                     YVLLSPYLKYNAPIMRPNSGGWAAPHTLRIVGLTMLNNIGIHQFDYVIAIDFNMPQEFR
                     NGTETLSYTHRLNTAFAPRNYKQDLCAITQPLLVLVGTADEAFIAEQFEPVFSQYTSAQ
                     VT"
ORIGIN
        1 ggtgcgattt agcaaatgca ccccaagttc atgctctagt cggttgatct gtttagagat
       61 aacagatcta tcaacatttc tttgttcggc caccttacta aatgagccca gttcagcgac
      121 ttcaagcaac agtaataatc gacttggaaa atccatacac cctctttgtt gcatttttag
      181 caccaatcaa gtgccagttt aagcattttt cttagcttat aacaacttta tagtagctcc
      241 actttaatgg cttaaacaaa ccgagccgac taaatcatga ggaagatatt atgagcaagt
      301 tatcaattag ccacagcgaa ggcatagcca ctgttagcat caataatcca ccatcgaatg
      361 taattaccag tgatttgatc aacgaagtta acgcctttgt tttatcgtta aaatatgacc
      421 gtgatactaa aatagtcgtg tttaaatcgc tccacccact gttcttttta gctcacttag
      481 atctgcatgt gatcaacggt acgactgcag gccaagctgc atcgattgag tttaatcaca
      541 tgatcaccaa cattaaagcc atgaagcagc tttcagttgc cgtggttgat ggcgtcgctc
      601 gcggcggtgg agatgaattt gtgatggcct gtgatttggc ttatgcaaca gaaaatgccg
      661 catttgctca acctgaaata catgtaaaca tcccaacagg tggccaaggc gcagtgcagt
      721 atgctcgcag gatgggcaaa aacaaagcac tacaagcctt attattaggt aatgacttca
      781 cagctcaaca agctgaagca ttaaatataa ttacccagta tgtcccgaaa tccgagatgg
      841 atgaattctt agcccaagta cttggcgtta ttgctcagtt agaaatacgt aatattctga
      901 tgtacaaaga gatcatcgcg gcatcaataa tagatgaaga tgctggcgcc gagctagagc
      961 tacgttattt tctagaacgt gcaaaagaga ataaaacaca agccatcatt gatgcattta
     1021 tcaagcatgg cggacaaact gaccgtgaag caaaggatat tcaagggatc tttgtcgata
     1081 cggcagcaga gcttgccaag tcattcaatg gctagatgca tatctagtat ggtcagctat
     1141 aaacacatct atggctgcca tattatttat attttgaatt actaaaaaaa gttattaaat
     1201 aagtagatga ccgtaaatcg gttaagtaaa ggtaaaggtg agatacgaag gtaatattta
     1261 tcgtccacca caagaggcgg acgcctacat actgcaatgc acaataggct gctcttacaa
     1321 caaatgcacc tattgctcta tgtacaaaga cgtacgttac cgagcaaggg atatcggtga
     1381 actgatagaa gatattcaga tggcaaaacg tgcttatgtc accaatatac aaaaaattga
     1441 aaaagtattc ttaagtgatg gggatgctat ttcattgccc accagcatgc tattagaaat
     1501 actggcagag ctttactctg catttccaaa cttaagccat gtcagtactt atgcaggccc
     1561 acaaagtaca ctgagtaaga cagaagaaga gttaacacaa ttaagacaag ccggactcac
     1621 tatgacctat ttaggggttg aatctggttc ggatgaagta ctcagtatga tccgtaaagg
     1681 cgttagcgcc gaagagatgc ttgtcgcagg ccgtaatatt gttgcttcag gcataaaact
     1741 agtcgcaatg gtgatgattg gtataggggg ccgtggtgaa atatcacaga ctcacataaa
     1801 agaaacggca acattaatca accagataaa accttaccta ctaggtacat taaccactgt
     1861 cgccattgaa gggactgttt tatataggca agttgccaag ggggagttta atttactcga
     1921 cccttatgaa gtactaaaag agatgaagat gttgctggaa catattgagc taccagcctt
     1981 atatattgat ggtactcacg catctaattt attaccaatt aaaggcttac ttaaagatga
     2041 taaacttaaa atgctagcat ctattaataa gtacttagac aacaaagacg aaagtttaat
     2101 cggtaaagct tactgtggcc gattttaaag tcagagattt taaagtcaga gattttaaag
     2161 tcagagattt taaagtcaga gattttaaag tcaaaataat gccagttcga cataaaaaag
     2221 ggctttataa tcagcccttt tttatgaatt agataacgag ttagggacgt atcaaccggc
     2281 gtatttatga gagatggggt cagtaatcac tattgtgtca cctcggagca tatagttacc
     2341 gccatgcaag tccatcactc cgtgatcatc gataaagcta agcactttaa acagcgtttt
     2401 tagcagctct tcatgctcat caataatctc atcatcaatt accactggct tgcgctcatc
     2461 tgagctcata taaaaatgcg ctcgtggctc ttggatctgc tcgacaaact catcaacact
     2521 tgaaacctca tcggtgaaag gcttctgtgg atcggcaaat ggcagggtca tggtacgcaa
     2581 ggtgccccag agtttgccaa agtcatcatc atgaaaatgg cttggacgag tgggctctgt
     2641 accgtcatcg gtgatgtctt caagacgctc cattacgtaa aaacgcacca ctcgaccgct
     2701 gctcaactcg acggtatctt cacgatggat agttggaaca tgggggttat cttgattttc
     2761 tgggcgcatg caccagcggg caaataggta gtaaccatct atcttactgt tacacagctt
     2821 gatgacttta tctggctctc cggggacttc gtacacctcg gcgtagatac cggtggcgat
     2881 tagatcaaga tctgtaaagc gctccagata tatcgataca tcatcaaccc gatggatctc
     2941 ctctgcgttt gctaactctt tgatctcttt aatcgcatca aggtaaagtt ccatcgatta
     3001 agccaccatt tacaacaaga aaaatttaga acaacggcta cgactaacac gcaaacgcta
     3061 tcatagccct ctaacaatgc cctaatgtgt cagacaataa atcaacaaaa taaatattgt
     3121 atgctcataa gttcaccact aaccattatc tcgtagctta gggtagcttt gcaaccatcg
     3181 cttttgcttc actctccgct caaacaacgc acgctttgct ttaggattgt gttgtagcga
     3241 cagatcaaac agacaagcta gatcaaacgg actatgtaaa atcaatgatg caggttctat
     3301 tattgcagtt gatgctgcca aagatttaaa tgttagcaaa cgactactca ccgccactgc
     3361 agtctgcttt tcaggccaat aactcatggc atcaagactt gatgtatatg cttgatgctg
     3421 gttgcgcaga tgcattctcg cttgattctt aaccgaccat gggtagatag gggctattcg
     3481 atttagctcg gcttcgattg cagtatccct ctcggcggat aggtcactcg agtcaaaata
     3541 gataaggtcg atatcattga gcgctgtttg caggccatgt aacttatccc aaactaaatt
     3601 gcggacaaaa cctgccgcta acatccaatc gtttaacttt agctgctcga caatgcgcaa
     3661 agcattaaac cggtactcat cttcgagtag ccagtgcttt atttgttgtt caaagtctat
     3721 tttaatggtc aatagtcact ctctttcaaa gcattaaaca ttcaactgct agggttatta
     3781 acttatacaa aactcgcctc aatacctaac tcaaacggct taataaacaa aaaaggagcc
     3841 ttagctcctt atttattctt tactgctacc tttactgcta tctaggggct ggcaccgctt
     3901 tcatcaacac ctcagtggta tacttgttat tattgatcac aggaaagcga tcataagtct
     3961 ggaaaatcac cttcccttga tattggatca tcgccaccac gccataatgg atgctgtcgt
     4021 caatgctatc tgctggcaat aaaaacttaa atggcacggg tgctctgacg atattaaagc
     4081 tcttttgcgc aacgataaca cccggggtat ctaggtcgat aatcgcgata gtaatcgagc
     4141 taccttgagg cagaggtaac ttctctagat aacccgccgc accattcacc accacaggcg
     4201 gcttatcttc aaccgtaaca caagctgtta ataccaacat acagagcagt acaacacttt
     4261 ttttcaataa tgagatcatg atttaaaccc taaatacaaa atataaacaa acagttgcgg
     4321 cattatgatg ttttcatcat ccgaataagc ccctcttgtg tcgctgatgc aacgagctcg
     4381 ccttgctgat taaaaaactg ccctctgaca aaacctcgac caccgctggc attgggactg
     4441 tctatggtat acaaaagcca ctggctcaag tcgaatgggc ggtgaaacca cattgcatga
     4501 tctatggtgg ccatacgcat accgggtgtt aaaaatgaaa ccccgtgtgg ctgagctgcc
     4561 gtaactaaaa agttaaagtc cgacgcatag gcgagcaaat aatcgtgcac agacatatta
     4621 tcaggcactt taccattagc gcggatccac acatgccgaa taggctcccg agctgccggt
     4681 gcgatcggat cacttgggtt gactaagcgc atctcaattg gcgtatcggc cataaacttt
     4741 tctagcactt tagacggcac tttatctcta agggtcatcg ctaactcttg ttgattaagc
     4801 aggccatcgg gtcccggcac atcaggcatc acggcttgat ggtcatagcc ttcttcagca
     4861 gtttgaaaag agcaggtcat atagaagatg ggacggcctt tctggatggc tttaactctt
     4921 cttgcactga agctgccacc atcacgcatg atttcaacat catacacaat aggtagtttc
     4981 tcatcgccgg cacgtaaaaa ataggagtgt aaagagtgca ccttacggtc aggactgaca
     5041 gtctgcttag ccgcacttaa ggcttgcccc atgacttgac caccaaagac gtgaccaaaa
     5101 cctagatctt ggctttgacc acgaaacagc cccacttcga tccgctctaa cgaaagtaac
     5161 gctaaaagat catctaatac ttggctcatt gcaacctaaa aatcagctaa ttatggccat
     5221 aagcttaact caagatcccc tagtctcgcc agttctactc aatctagcac tactctaata
     5281 cgatacggcg ctgatttgcc gatgcctttg cccaagccag cacctgcgcc tcgccacttc
     5341 gatgagcggt aacgggtttt gcatggtaga gctcaggcca acgctcggtg atcacttcag
     5401 gggtacactc ctcggcttta aagcgtcccg gagaaaactc aacaagagcg gcatggctaa
     5461 ttccgccagc cgccgcgagc aggtgttcac ccgatgggct tttagaacta cacaggtaca
     5521 acatggtggc cgtaacggtt gtttttgaaa aaagtggacg aactgttggg gctaaatgct
     5581 ctgccgtcat cgatgtgact gcatggggaa taatactgtt aaccttgatc ccgtgttctg
     5641 cgccctcaag gtgcaaactg ttgaccagtc ccatcaccgc cattttgctc gtgctaaagc
     5701 tggtttcata catatcaccg tagatggagc ttgcactact catcacaact cggccataac
     5761 tttgacgctt cataaaaggc cacacggctt gagtcatgta gaaggttcca ttgagatcca
     5821 catccagatt atgcttccaa ctcgaggcac tcatctgctc aaatgcacag gacttatgaa
     5881 tacccgcatt attaattaag atatcgacac gaccccaact ttttaccaca tcatcaacca
     5941 ttgagttaat atcatcgatg ctggtgacat ccaatgtaaa agacttgaac tcacctccta
     6001 acgccgttat cgctgcaccg caagcttgca ggcctgaatc aggctctagg tttgtcatgc
     6061 tggagctaac atcctttgtt tgagtcgttt cattatcaac caaaacgact cgtgctcctc
     6121 gctcagctaa ggcaatcgca taggctctac caagacccga tgctgcgccc gtaactattg
     6181 cgacttgtcc ctcaaaacgc atagtttcga cccctaaaca gatttgtcta tcacaaatgt
     6241 agacgttgac tgctaagaaa gcagtttcat ttctaaagcg acaattacaa cttctcatct
     6301 tgctcccgct ttagagatat aatattgcat acactcctgc ctaacagatg tgcgctagtt
     6361 caaagttctt caatcagtca aagtgaaaaa taataatgct taacaaagtg ttaagccgac
     6421 cacttttgat gatataaaat ccacttttta gaagttgtta aatttgctat gctatgccaa
     6481 ctttttttac ctttatgtca gctttctttg acgtaaacct ctgtaagtaa atataaacca
     6541 tgaatccttg gatacttgcc atccgccctc gcaccttgcc tgcggcgatt ggaccactgc
     6601 tggttggtaa cgtactcgca ctgcaactgg aacagttcag ctttttcatt gctgttattt
     6661 caatgctctg cgccctgcta ctgcaaattg ccgtaaacct agccaatgac tatttcgact
     6721 ttaaaagtgg tgtcgatacc gaagagcgct tagggcctgt tcgtgtcacc caaagtggca
     6781 tgcttagccc aatggctgtg cgtaacgcaa tgattttgtg cctagtgttg gcacttatcg
     6841 ttggttcttt gcttatctac cacggtggcc taccgatcgc ctttttagcg gtggcagcga
     6901 ttcttggcgc cttaggctat agcggcggtc cttacccact ggcctctcat ggtttaggtg
     6961 aagttgccgc atttgtattt tttggtcttg tggctgttgt cggaagttac tttctgcaag
     7021 cgggtgaaac tgcaactagc gcatggctac ttggcagcgc catcggcttt ttaaatgcag
     7081 cgattatgct agtgaataac acccgagata tggaaaccga tattaaggca ggtaaaaaga
     7141 ccttagcggt tcgtatgggt cttgcacaat cgcgtatttt ctatcaaagc tttctctatc
     7201 tgccatttgc catcattttt gcaggcttcc tgatgggagc actaccaggt ttaccggtgc
     7261 ttttagctgg actcgcattt gtcatggcga gaagcttaag taatgatttt aatgaagtca
     7321 ctggggcagc cttaaaccca ttacttgggc gcacagctaa gctcaccatg attttcagcg
     7381 cattatttag tatcggtcta ctgggcgata tctatctgtt cgtgacctag tctagccatt
     7441 cgctagcctc taatgagcaa taaaaaagcc tatcgattga taggcttttt tgtatgtaca
     7501 gctcagagta aagacaccga attacatctt atgtaaactg cgatctccac tccagttcag
     7561 gtgatacttc tcacccgctg gcttgtcggt tcgctcaaaa gtatgggcac cgaaaaagtc
     7621 tcgctgccct tgtagtaaac tcgctggcaa ggtttcacag cgataactgt cgtaataagc
     7681 taaagccgaa ctgatacaag gcgcgggtat accactcagt acggcttgcg atacggcttc
     7741 tctccaatct tgttgttttt cagacaaagc tttagcaaaa gagtctgcca tcagcaggtt
     7801 ttcaagctca ctatcttgct gatatgcctt ggtgatcgat tgcaagaaag tggcgcggat
     7861 aatacagccg gcccgccaaa ttttagcgat ttcagcaaaa tccaactgcc aagcttgctc
     7921 cttagcttgc atagccatca actgaaaacc ttgggcgtag caagacactt tggcgcaata
     7981 gagcgcattt tcaagctgag cgataaatgt ctgcttttca ccacggttaa tcgtggccaa
     8041 cagcgcttcg cttggcccgg ataactgttg gctaagttgc tgtctttgag ctttttgagt
     8101 actgactgcg cgggcataaa ccgcttcagc gatggtgggt gctgggcagc ctatctgtaa
     8161 actgcttacc gcagtccaaa gacccgtgcc tttttgcccc gccttatcca agatcatatc
     8221 gaccagtggc gccccggtta atgggtctgc ttgtttgagc acatcggcgc tgatctgcat
     8281 caagtagctg tttaagatcc cttgatccca ccgttcaaac acatcaccca cttcactcgg
     8341 tgataatcct aagccctgat ttaatagctg ataagcctcg cagataagtt gcatgtcagc
     8401 atattcaata ccgttatgta ccattttaac gtaatgacca gaacccgcag gaccaatata
     8461 ggtggtacaa ggctcgcctt ctttcacggg gtttcccggc tcaaaacgct cgataggcaa
     8521 acctgtttta gcatcgactt tagcggcaat tgcttgccat attggctcaa ttctattcca
     8581 ggcttttaag ctgccacttg gcatcagaga tggaccaaaa cgcgcaccga cttcaccacc
     8641 tgataccgcg cagctaaaga aaagaaaatt gtcggcgtag cgcttctcgc gctcaaccgt
     8701 atccgtccat aagctgttac ctgtatcaat cacgatatca tcattctcga tcccggcttc
     8761 aattagagac tgacaaacac cgtcgacagg agctcctgcc ggtacagata gaagcagtac
     8821 gcggggcttt tctaatttag ataacatttc agaaagattg ttacagcctt ctattcgtgg
     8881 ctcagttatc tgttttaggt atcgcttacg ctctagttct tcttgtgcaa cagtgtcttg
     8941 caccttgagt tcatcaaggt caaatgcagc gacgcgatat tggttgtcgg ctatattaag
     9001 tgcaaggttc ttacccatta cgcccaagcc aataacaccg atatcgtaaa gatttgattg
     9061 gttcttcatg tagatttctt ccgtaggtca cagagaatta cccgtctatt attttatata
     9121 ggcaacaata gctggtgctg cctattggag tgacgggttt aattttgtta gcgattatac
     9181 agactttggt aacttaatta ctaggcaaag ccaaatgagt taacaactca acattaataa
     9241 ttggtgttaa taataaacag taaatttagt tcaaaaacaa aaaactgaaa cctaagtttc
     9301 agctttttct ctgcgtttgc aagttaacgg ttagccgagc actacctcca ataagctaat
     9361 acctatcggt atacctcttt aattcgatat agctttttga cagaaatacc tctttgatag
     9421 aaatagctct ttgatagaaa tagtcccatt tagtaagcat gctccccctg acggcataaa
     9481 tgccgaccta cactaacaat gctggagcgg cttaaatatc aacctttgct tttgcagctt
     9541 gtatcgtctt agctttcctc gttcctataa cttgcttttc ttagaacctg tctttgcttt
     9601 tcctgcttgt atcgtctcag atttcctcgt ctctagaact tgctttgcct agaacctagc
     9661 tttgattttc ctgcttgtat cgtcttagct ttcctcgtct ctagaacttg cttttcctag
     9721 gacctagctt tggttttcct gcttgtatcg tctcagattt cctcgtctct agaacttgct
     9781 tttcctagaa cgtagctttg attttcctgc ttgtatcgtc tcagctttcc tcgtctctag
     9841 aacttgcttt tcctagtacc tagctttggt tttcctgctt gtatcgtctc agatttcctc
     9901 gtctctagaa cttgcttttc ctagaacctg gctttgattt tcctgcttgt atcgtcttag
     9961 ctttcctcgt acctagaacc tgcttttcct aggaccttct ttaaacatgc gcatctgcat
    10021 agcccatacg ggttaaggtg ttacgcacga tatcgagtgt agcgggatct tcgatagtcg
    10081 ccggcacatt gtaactttga ttgtcggcga tattgcgcat ggtgccacgt aagatcttgc
    10141 cacttcgggt tttcggcaat ttctgcaccg cactcaccaa tctaaaagat gctactggcc
    10201 ctatctcttg acgcactaaa ctcattaatt gctgatttaa gtcatcatca ttaaggctta
    10261 cacctttttt tagtacgact aagccaagtg gtacttgccc cttaagtacg tctttaacac
    10321 cgatcaccgc cgcctcagcc actgcctcat gttgacaaag cacctcttca aagcggccag
    10381 tagagagtcg gtgcccagcc acatttataa tgtcatcgat acgactcata atgtacaagt
    10441 aaccgtcttc atctttataa cccgcatcac ccgttaggta atagccggga tacattgaaa
    10501 ggtagctatc ttgataacgt tgctcatttt gccatagcgt agttagcgtc cccggcggca
    10561 gtggcagttt aatcaccaca ttaccggact cattggcctc gacttcatcg cccatgacat
    10621 caaccacttc gatttgataa ccgggcaccg ctaatgcagg agagcccgcc ttgatctcga
    10681 ctggcgcgta gcccatcaag ttagccgcca caggccagcc cgtttctgtc tgccaccagt
    10741 ggtcaatcac aggcttttta agcttgcctt cggtccagtg caaggtgtca ggatcgcagc
    10801 gctcacccgc taagaacaca ttctttaaac agcttaagtc taccccctct agatagtcac
    10861 catggggatc atcacgcttg atggctcgaa tagccgttgg ggcagtaaag aagcttttga
    10921 ccctgtattt tgcaatggtg cgccaaaatg cgccgggatc aggcgtgcca atcggtttac
    10981 cttcatacaa gatacttgtc gccccgacga gtaatggtcc atagacgata taagagtggc
    11041 ccacaaccca gccgacatcc gatgcggccc agaatacatc ccccgcatta atgtcataga
    11101 tatgcttcat cgaccaagcg agcgccacgg catggccgcc gttgtcgcgc accacacctt
    11161 tgggttgccc tgtggtgcca gaggtataca agatataaag cggatcagtg gcatcgagtg
    11221 gttggcaatc gatattagga gcggctgcca ccgctgcctg ccagtcgata tcccgtcctg
    11281 gaaataactc agcttcaagc tggcctcggt ttaacactaa gcaatgatcg actttatgag
    11341 tggcttgatc taacgccgca tcgagtagcg gtttgtaggg gataatgcct gacggctcga
    11401 tgccacaaga tgctgaaagg ataagtttag gtttggcatc attaatacgg gtcgcgagtt
    11461 cattggctgc aaagccgcca aacaccaccg aatgaattgc gccaatgcgc gcgcaggcaa
    11521 gcatggcaaa tgccgtttct ggcaccatag gcatataaat aacaacccta tcgccctttt
    11581 tcacgccaat agagtccata tagccagcga gccggctcac ttgagccagc agctctcgat
    11641 atgaaatacc gtattcaaca tcggtaacgg gactcacata ttgcagcgct atctgatcgc
    11701 ctcgtccagc gtcaacatgt ctatccaccg cgttataaca agtgttgagc ttgccgcctt
    11761 taaaccagtg gtaaaacggc gcttcactgt catcgagtac attattccaa ggggagaacc
    11821 aatcgatttg gctagcggct tcggcccaga atgcctctgg ttggttaatt gatttggcat
    11881 gtaattgctt attcttattt ttcacaatac tgactccact ttgctagatc tcgataacat
    11941 atcgcatcgt tcatgagcga cttttgtcca tttaatgctt taacgcatta tgctctgacg
    12001 attaaaaaat ccccattaga ccttagaatg agtaagttaa ggaggaattt aacgagctaa
    12061 aaaaatacat agcgtttaac tcaacccaat gttaataaac aataaacatg aaaaactaat
    12121 gagtaatctg caacctcgtt ctctgctaat acaagtgctg tggcaagcgc gattgacatg
    12181 aaaacgactt catccaacag gtacaaactt tacctttacg taaacttcat atatcgttca
    12241 attaatgtaa acaattatgg tgttatttga tggtagagaa accgctctca caaacgacat
    12301 actcaatcag tgacttatct aaagagtttg atatcactac tcgtagtatt cgtttttatg
    12361 aagaccaagg ccttttaaaa cctaagcgcc gtggtcaaac acgcgtatac agccttaaag
    12421 atagagtcag gctgaagctt attctgcgtg gtaagcgttt aggtttctca ctggccgaaa
    12481 caaggcgctt attcgagctt tatgatgctg acaagaatag cagtggtcag ctgcatacca
    12541 tgctcgagct agtcgaagag aaaaaggtat cactacagca acagatggat gacatcaagg
    12601 tcgtgctgat ggagctgaat tcggcagagc aacaatgctt agaggctcta gaaaataacg
    12661 cccaataatg gccttttcta tcgctattaa ttacatatga atttccaagt atcacggcaa
    12721 agatcgctga gcttgaacac aaacaaaatt gacaggacac aagcaaatga ctcaactcta
    12781 cacctctcta aactttggcc tcggcgaaga agtcgatatg ttacgcgatg cagtgcaaag
    12841 cttcgccgct aacaaaatcg cccctatcgc cgcaaaaaca gatctcgaca acgcctttcc
    12901 taatgagctt tggccggttc ttggcgacat gggactgctg ggcgtcacag tttcagagga
    12961 gtatggcggc gctgaaatgg gctacctcgc ccacgtggtt gccatggagg agatctctcg
    13021 cgcctcagca tcaattggct taagttatgg cgctcactct aatctgtgtg ttaaccaaat
    13081 caaccgtaac ggcaacagtg agcaaaaggc caagtattta cccaagctta tcactggcga
    13141 gcacattggc gcgcttgcca tgagtgagcc aaatgcaggc tctgacgtag tatcgatgaa
    13201 actacacgcc cgtaaagagg gggatagata catactcaac ggcaacaaga tgtggatcac
    13261 taacggtcct gacgcccaca cctatgttat ctatgccaag actgatctcg ataaaggcgc
    13321 ccacggcatt accgcattta tcgttgagcg cggctctaaa ggcttcagca ccgctcagaa
    13381 gctagacaag ctaggcatgc gtggttctaa cacctgtgaa ctggtatttg aagattgtga
    13441 agtaccagaa gagaacattc ttggcggcct aaacaacggc gtaaaggtgt tgatgagtgg
    13501 cctcgattac gagcgagtgg tgctgtctgg tggcccactt gggataatga ctgcttgtat
    13561 ggatatcgtt gtgccataca ttcacgagcg tgagcagttt ggtaaatcga tcggacagtt
    13621 ccagctagta cagggtaagc ttgccgacat gtataccggc atgaacgctg ccaaatctta
    13681 tatctacaac gtggctaaat cttgtgaccg tggggaaacc acccgtaaag atgcagccgg
    13741 cgccattctc tattcagctg aacttgccac caagatggct ctcgatgcga ttcaacttct
    13801 tggcggtaac ggttatgtca acgaatacgc cacaggccgc ctcctacgtg atgccaaact
    13861 ctatgaaatt ggcgctggca cctctgaaat tcgtcgcatg ctgattggcc gcgagctatt
    13921 taatgaatca aagtaaagcc tatgcccgtc ttgcgggttt atagccaagc ataaaggcgg
    13981 cgatttgccg cctcactctt ccagcttcaa aaggattgaa attgtgacgc aacttagcag
    14041 ccgtattaat gcacgtagcg atgagtttaa agctaaattt gatgacatgg ctaccgtggt
    14101 tcaagactta aaattaaaac ttcagcaaat tgaacaaggc ggcggagacg tcgcgcgcag
    14161 tcgtcatctt tcaaggggca agttgctgcc acgtcagcga gtcgaaaagc tgctggatcc
    14221 tggctcacct tttctcgaaa tatcccagtt tgccgccttt gagctgtatg aagatgtggt
    14281 gcctgctgca ggcgttatcg ccggtattgg ccgcgtcagt ggcgtcgagt gcatgattat
    14341 cgccaacgat gccacggtaa agggcggcac ttactacccg gttaccgtta aaaagcatct
    14401 gcgcgcacaa gagattgcca gtcgttgcca cctaccctgt atctatctgg tggattctgg
    14461 cggcgctaac ctgcctcgcc aagacgaagt attccccgat agagatcatt tcggccgcat
    14521 cttctataac caagcgcaga tgtctgccaa aggcattccg caaattgccg tggtgatggg
    14581 gctttgcact gcaggcggcg catatgtccc cgccatggcc gatgaatcga ttatcgtaaa
    14641 agagcaaggc accatcttct tagcggggcc gccactcgtt aaggccgcaa ccggtgaaga
    14701 ggtgacagcc gaagagcttg gcggcgccga agtacacacc aaaatttctg gcgtagccga
    14761 tcatatggcg caaaacgatg aacacgcgct agagcttgct cgcaaagcgg tgacacgcct
    14821 aaatcatcaa aaacaaattg ctgctcaact tagcccggta aaacctcccc tatttgatat
    14881 caatgagctg tacggcattg tgggtaccga tcttaaaaag ccattcgatg tcaaagaggt
    14941 gattgcacgc cttgtcgatg actcagactt cgacgagttt aaagccaact acggtaatac
    15001 cttagtctgt ggctttgccc gtattcatgg ctatcccgtg ggtattgtcg ccaataatgg
    15061 catcttgttc tcagaatcgg cgcaaaaagg cgctcacttt attgagctgt gctgccagcg
    15121 caaaattcca ctgctgttcc tgcaaaatat caccggcttt atggtgggta aaaagtacga
    15181 acatgaaggc atcgccaaac acggcgccaa gatggtgacc gcagtatcgt gtgccaatgt
    15241 ccctaagttc accgtgatta ttggcggtag ttatggcgca ggtaactacg gtatgtgtgg
    15301 ccgcgcattt gaacccacca tgatgtggat gtggcctaac gcccgcatct ctgtgatggg
    15361 cggcgagcaa gccgctggcg tattggccac agttaagcgc gatggcctcg cccgtaaagg
    15421 ggttgaatgg tcaaatgatg aagaacaagc attccgtcaa ccgatagttg agcaatacga
    15481 taaagagggc cacccgtatc atgccagcgc ccgtttgtgg gacgacggta ttatcgaccc
    15541 ggctcaaacc cgtgatgttg ttggcttggc gctctctgcc gcgctaaatg cccctattga
    15601 ggagacgaag tttggtgtat tccgtatgta atggctaagg ctattaaggc aaggaacatc
    15661 gacttagaac acactatgga tcgacaacaa tgaataactc aatcacaacc gacacagaac
    15721 gactgactca acaattacaa tatgtgagct gcacgctcga tggcggcgta gcccagatgg
    15781 tgctcgaccg agccgataag cataacgcct tcgatgaagt gatgataagc gaaatgatta
    15841 aggtgctgga gcatttcagt gccaatgttc agtgccaagt attagtgata aaagccaacg
    15901 gtaaaaactt cagcgccggc gccgatctca actggatgcg caagcaagcc aagatggact
    15961 ttggccagaa tctcagtgac gccaacgagc ttgccaagct gatgtcactg ctggataaat
    16021 tccccaagcc gacgattgca ttagtgcaag gggcggcatt tggtggcgca cttgggctta
    16081 tctgctgcag cgatatcgct atcgccaatc agcgtgccag cttctgcttg agtgaagtca
    16141 aacttgggct cattccagcg gtcattagcc cctatgtcac tcgcgccatg ggtcaacgcg
    16201 cagcacggcg ttacatgctc acagctgaac gcttcgatgt tcaaaaggcg cttgaactgc
    16261 aagtcatcca tgaagtgaat gacgacttag atgctgcggc tcagccgatg attgatgcgc
    16321 tactctgcaa cagtccactg ggcatgactt gggttaaaac cttactgtta tcgcttgaag
    16381 atggcgtgat agaccaaaac accttggact ataccagcga acggatcgcc cgtattcgag
    16441 tgtcagaaga aggtcaagag ggcctcaacg ccttctttga aaaacgttca ccacaatggc
    16501 ctgcaaccac agactttaac gctgcaacaa aaaataataa ccagagcgcc agcgggcaag
    16561 gagccaaata atatgttcac taaattgcta attgcgaacc gcggtgaaat cgcctgtcgc
    16621 atcattaaca ccgctaaagt catgggcgtt cgtacggttg ctttatattc agatgccgat
    16681 atcgatgctc gccatgtcgc catggccgat gaggcatttt acttaggtgg cagcgcgcca
    16741 gctgactctt accttaaagg cgagctgatc attgagatcg ccaaacgagc aggcgcagag
    16801 gcgatacacc caggttatgg tttcctatcg gaaaacgccg attttgcatt gaagtgcgaa
    16861 caggccaata tcgcctttgt tggcccaagc gccgctgcaa ttgactcgat gggcagtaag
    16921 agcgccgcta aagagatcat gggtgctgcc aatgtaccat tagtccccgg ctatcacggt
    16981 gatgctcaga acgatgaact acttgttagt gaagccaaca agatgggctt cccgctgctg
    17041 attaaggcgg cctttggcgg cggtggtaaa ggcatgcgca tcgttgaaag taacaatgag
    17101 gtgctcgatg cgattcactc tgcgaggcgt gaagcgatta gctcttttgg taacgataag
    17161 ctgttaatgg agcgctacct gcgccagccg cgccatgttg aggtccaagt ctttgccgat
    17221 agccatggca actgcatcta cctgtctgac cgagattgct caattcaacg ccgtcatcaa
    17281 aaggtggttg aggaagcgcc agccccaggg cttagcgatg ccctcagagt caagatgggc
    17341 gaagcggccg ttgccgcagc taaggcgatt aactatgaag gcgcgggaac agttgagttt
    17401 ttactcgata ccgatgacag cttctacttt atggagatga atacccgtct gcaggtagag
    17461 catcccgtca ccgagctcgt cacaggccaa gacttagtca aatggcaatt aatggttgcc
    17521 agtggtagtc cgttacccct taaacagaat gaagtgcgca ttgtaggcca tgcttttgag
    17581 gcgcggatct acgccgaaga tccacacaat gacttcctgc ctgccagtgg caaactcgat
    17641 tttctgcgcg agcctgagca gagccaattt gtgcgtatcg attctggcgt gcgtgaaaat
    17701 gatgtgatca gtaactttta cgacccgatg atctcaaagc ttatcacttg ggatgagtca
    17761 cgccctcgcg cgctacaacg cttagtgcat gcattagatg attaccagat cagtggcctt
    17821 aaacataata tcgaattcct cgctaatatt gctaagcatc aagcttttag cgatgccaac
    17881 tttagcaccg attttatcga gcgttatggt gatgcgctat taaccgcaca atcaaatgca
    17941 actccatcga ctcgtcgcga tacagcattg gcgatagcgg cgctgtacca gctatgtgcc
    18001 cgtaaaaaac aagctaaaaa cgacacattg accagccatg atccctactc accttggggc
    18061 aaagtgagtg gctttaggct caacagtgct agccaacatc aagtggcgtt actcgatgat
    18121 aatcatgaga ttaatcacct tgagctaatc gagacgcaag tcgctggaaa gccacaatac
    18181 cagctgcagc tgagtgataa cttactcacc ctttctggcg agctaattga cgagatcctg
    18241 catgctgaaa ttgttcaaca caagctgggc gatagccaag ctgagcaagc cagtaaagct
    18301 aacggccata aaataaagct cccagttagc caagtcggca atgactttac cctgtttatc
    18361 aactcaaaaa gctaccacta tcgcgcccta gaatcagaag agattgaaga gcaagacaat
    18421 cttgaagata agctcaaagc accaatgaac ggcactatcg tcactcaact tgtcagcgtt
    18481 ggcgatgtgg taaaagcggg ccaaggcatt atggtgatgg aagcgatgaa gatggaatac
    18541 accatagagt ccccctttga cggtgttgtc agtgcattct tcttcgagcc cggtgaactc
    18601 gtcagcgacg gtatgttact tgccgaggtc gtggctgaag ttgaagcaga agtaaaccct
    18661 gaaaaggaag aagccggatg aagatgacta atgtaataaa cgccattgag tctccgtttg
    18721 acggtgttgt cggtgcattc ttcttcgagc ccggtgaact cgtcagcgac ggtatgttac
    18781 tagccgaagt tgaggctaaa gttgagactg cagagcttga gccaacagaa actgtggctg
    18841 cggaggaaag cgcataaatg gcaatctctt acccacaaca agtcagtatc tttgaagtcg
    18901 gcgcccgtga tggtctacaa aacgaaaaac cggtcacgac ccaagataaa atagtcttga
    18961 tagaggactt agcgactgcg ggcgttaagc gaattgaagc cgccagcttt gtgtcaccta
    19021 aatgggtgcc acagatggca gattcagccg atgtgctcgt gggcatcact cgccacaagg
    19081 gcgtaaccta cagtgcgctc actccaaatt taaaaggttt ggaactcgca cttgaagctg
    19141 gcgccgatga agtcgccatc tttggcgccg cctcagaaag ctttagccag aagaatatca
    19201 actgctcgat agaggagtcg attgagcgct ttatcccagt aatggagctg gctaaggcca
    19261 agaatgtccc ggttcgaggt tacgtctctt gtaccttagg ctgcccttat gagggggaga
    19321 tagccgttag tgaagtggct cgggtgtctg aattacttta ccaaatgggc tgttatgaga
    19381 tctcgcttgg cgacaccata ggcgttggca caccacttaa tgcccgtaga atggttgaag
    19441 cggtggcaga agtggtgcca aaagacaaac tggcgctgca ttttcacgat acctatggcc
    19501 aagccttagc caacattctg gcctgcttag aaaccggtgt cagcgtaatt gactcatcgg
    19561 tcgcaggcct tggcggctgc ccctacgcta aaggcgcatc gggtaactta gccacagaag
    19621 acttagttta tatgctacac gggcttggca tagaaaccgg tatcgactta actaaactgg
    19681 ttaatgcggg caataaaatc agccacgccc tcggacgcca gtcgggctct aaagtggcaa
    19741 gagccctcag cgaatagaga gccatcagcg aataaaaagc aagaagatcc tagatcctag
    19801 catttgacag aataaggaga taacaataat ggcaggacta aataaagagc caaatcaagg
    19861 gctgaataag gtcgtcacca gttatgaaga ggccttaaaa ggcctaacta acaatatgac
    19921 agtgatggtc ggcggctttg gcttatgcgg catacccgaa ggcttaattg cgcaaatggt
    19981 caagactggt gtcaccggac tgaccgctat ctcaaataat gctggcgtcg atgactttgg
    20041 tttaggcctg ttattaaaga gccgtcaaat tgataccatg attgcctcat acgtgggtga
    20101 aaacgccacc ttcgagcagc agatgttatc tggtgagctt aacgttatct tgaccccaca
    20161 aggtaccttg gccgagaaaa ttcgtgccgg cggtgcgggc attcccgctt tctttaccgc
    20221 gacaggctac ggtacgcctg tagccgaggg taaagaaacc cgcgaaattg atggccgtca
    20281 ctatgtgtta gagcccgcac taaaagcgga ctttgcgctg gttcgtgcat ggaaagcaga
    20341 caccatgggt aacttagtgt tccgaaagac cgcagccaac ttcaacccca tgatggcaac
    20401 cgcaggcaag atcaccgtgg tagaggctga gcatatcgtc cagcctgggg agctcgatcc
    20461 tgatcatatt catacacccg gcatttacgt caaccgtgtg attcaaggta agttcgagaa
    20521 acgtatcgag caacgcacag ttaaaccaga ctctaaatca agagctgaat caagaactga
    20581 tgaaaaagca taaggaggca gcaccatggc attatcaaga gaacaactgg cacagcgtgt
    20641 agcacaagaa ctccaagatg gcttttacgt caacttaggt attggtatcc caaccttagt
    20701 ggccaactat attcctgaag gcatcgacgt gatgctgcag tcagaaaatg gcttgctggg
    20761 catgggcgag ttccccaccg aagaaaccat cgatgccgat ctcattaacg ctggtaagca
    20821 aacggttacc gcggttgatg gcgcgtcatt tttctcatca gcagagagct ttgccatgat
    20881 ccgtggagga catgtggatc tcaccgtcct cggcgcattt gaagtggatg agcaaggctc
    20941 tatcgcctcg tggatgatcc cgggcaagct gattaaaggc atgggcggcg caatggactt
    21001 agttgctggc gctgacaaca tcatcgtcac catgatgcac gccgacaaga aaggtaattc
    21061 taagttactg ccaaagtgtg aactgccact gaccggctat ggctgtatca agcgcgtgtt
    21121 aactgactta gcctttatgg aaatcaaaga tggcgccttt catctgctag aacgtgcacc
    21181 gggggtgtcg gtagaggaga taatctccaa aactgcaggc aagcttgtag tgccagaata
    21241 tgtgccagag atgagctttt aacgacaagc tattcgataa agcaagttga tagagccagt
    21301 tgataaagca agtagattga gcgattaaac acaaaacgca gcttaatata agctgcgttt
    21361 ttccatctga gtattagtta agtgtcactc ccaactttgg gcgcactcgc tccaataatt
    21421 gacaaataaa tacaaaaaac accggtacaa atagcacagc aaataccgtg ccggtaaaca
    21481 tgccaccaag gaccccagta ccaatcgaat tttgaatttc agagcttggg cctgtggcta
    21541 agtaaagtgg aataatgccg cagctaaagg ccaaagacgt catcaaaatg ggtctaagcc
    21601 tttgcttagt tgcctgcaat acggaatcga cgaggcagat cccttccgcc tgagcctgct
    21661 tggcaaactc gacgataaga atggcattct tagccgacaa gccaatgata gtcaccaaac
    21721 caactttaaa gaatacatcg tttgccacac catttaatag cacgaagccc acagcaccaa
    21781 taatgcctaa tggcaccacc aaaataacgg ctaacgggat agaccagctt tcatacagcg
    21841 ccgccaatac taagaaaata accagcattg aaaacagtaa taaccatact gtttgtgact
    21901 ccgcttgttt ttcttgcagt gaaagccctg tccattcgat gcctgcagcc gttggcagtg
    21961 aagcagcaat acgctccacc tcctgcatag cctctccagt agagtatccc ggtgcaggag
    22021 acgccgacac cgcaacggct aataaaccat taaatcgggt cagttgttgc ggcgccattt
    22081 gccacacagg ggtgacaaat tcagagagat aaaccgtgcc gccttgctca ttgcggatag
    22141 ccagttgcaa tatatcctca agttgcattc ttgactcagc ttgaacttga acaatcacct
    22201 gttgcaagcg gccattatta ggaaaatcat taacgtaatt agagcccatt gcagtagaga
    22261 ttgtgtcgct aatcgcgtta aaaggcaccc ctagcgcccg cgctttggcg cgatcaatat
    22321 ttaggtgtat gccactggtt tcaggcagcg cttcatagaa cacagatgat agcttttcac
    22381 tggcatatgc ctgctcaagg aattcctttt ggatcaattg gaaacgctcg taacctgcat
    22441 taccactgtc ttgtaattga aaagataaat tggatgagtt gcccaagcca tctatcgcag
    22501 cgggtaacac actaaacact tctccttccg ttaaatcact taaataatca cttaacgctg
    22561 ccacttcctg ttgtgtagag ctaccaccac gtagctgcca gtcttttaat gtcgtaatgc
    22621 caaaggcaga gcctgggcca gtaccactaa aactgaaacc aagaacactc atgctggcat
    22681 caatggcctc tcgacctaaa gtaaacgcct caattttact caccacatcc atagttcgct
    22741 ctaccgtcgc atcaggcggc agctggatag acgtcatata gtagccttga tcttcttcgg
    22801 gtaaaaaggt gctcggcact agagtaaagc tataaataca tgccaccaca agtacgatgt
    22861 aaagtgccat cactctgccc gttcgcttaa cgagatgggc aacaccagct gtcacttttt
    22921 gggtgaaatt gtggaagtta cgattaaacc agccaaaaaa accaccgctt ttatggtcat
    22981 gctcagtcaa aggctttaat aaagttgcgc acaaagctgg cgtcaatgtt aaggctaaga
    23041 aggccgagaa taaaatcgac actgccattg caagcgagaa ctgctggaaa attgtgccta
    23101 ccgagcccga tgcaaatgcc attgggataa ataccgcaga taacacagcc gtaatcccaa
    23161 taacagcgct atagatgctt ttcatcgcct gctctgttgc cgctttgggt ggcaagcctg
    23221 tttcagccat tactcgttca acgttttcaa ccactacgat ggcatcgtca acaataatac
    23281 cgatagccaa caccatacca aacatagtga acacattgat ggaaaagccc attagccaca
    23341 tcaccgcaaa cgtacccagc aacgcaatcg gagcgacaat cgcggggata agggtatagc
    23401 ggattttttg caaaaacagg tacatcacta aaaacaccaa caccattgct tcgagcagtg
    23461 tcacgacaac cttttgaatg gatattttgg caaagatagc cgcatcggag gtgatcgaat
    23521 agtccatatt gctgggcatg gcaagcttaa gctcagccaa tcggtctctg atcccttgcg
    23581 aagtcgcaat cgcattcgct ccaggcgata gctgaatcgc agcagatgtc gactgctgac
    23641 cattttcccg attactaaac aggtaatttt gtgccccaag ctcaacctta gctacatctc
    23701 ctaattggac catgccagca tcaatatttg aacgcagcac aatggctcta aactgctctg
    23761 gggtttctaa ttgcccttgg gcagttagag agtgcaccgt catttggccg ccagatgtcg
    23821 gagaatcacc gactttaccg ggagaaatct gcacattttg ctctgcaatg gctgatgtca
    23881 catcttccat cgttaagtta tagcccgtca acgccaccgg gtcgacccag atccgcatcg
    23941 caaactcagc gccatacatc tgtactcgtc ccacaccggg cacgcgcttt atctcctcaa
    24001 cgatatttcg caccatgtag tcactcagtt gctgctctga atattcgcca ctcggtgaga
    24061 taagccctaa atacatcagg ttatttgaag aagtggtttc caccgtgatg ccgatttgac
    24121 gaaccgctaa aggtagtctt ggctcaatgg ctctgatctt gttttggatc tcaacctgag
    24181 ccatctcagg atcggtacca ttttcaaagg tcaccgtaat tgaggcgctt ccgctagcat
    24241 ctgacgagga gctaaaataa agcagaccat taatccctga gatctcccgc tcaatcaagg
    24301 tcacaacact gtcattaatc gtttgtggac tcgcgccagg gtaagataag tacaaaccaa
    24361 tactcggcgg cgcaacgcta ggaaaacgct cgacagccaa cttaggaatg gcgatcactc
    24421 cagcgatgct aattaaaata gcaataaccc atgcaaaaac aggtcgagaa ataaaaaaat
    24481 acgacacaat aaacttcctc ttacgctatc cgttgataca ttactgctgc caatcagaca
    24541 ggactaactc agccccttcg cgcaggttat cttggccagt cactaccact atatcgtttg
    24601 gattaactcc tttcgaaatt acatatcgtc gctgttgcag cccttctagt tgtacaggtc
    24661 ttagctcaaa cttgtcgtta acaacaatgt agacaaacgg taagcccgca ctgttgcggc
    24721 gaaccgcgtg ttcaggaacc gtgattgctt gcaatttctg acgcgggatc tgggttcgta
    24781 cgtacattcc aggtaagagt ttttgctgcg cattatcggc aataatacga ataatcagat
    24841 caccggtatt ttcatcaacg ctgatccctg aaaacaaaat ttgtccttcg atatcatctg
    24901 cactctctgc agacgactgc acaatcacct tgaccccttg ctcactgttt ttctgttcat
    24961 tggctaataa acgtcgcaat aacccaagtt tcgatgcggg ttgacgaaca tcaatataga
    25021 ccttatcaat ctgctgaatg atggctaatg gctgtggctc ggtacggcta actaaacttc
    25081 cctcagtcac taatgcctca ccgataatcc cagagatagg tgcagtcact ttcgcatact
    25141 caagttgtaa ctcactatgc ttaagttggg ctcgattttg ctgcactgtg gcggctgcaa
    25201 tttgtaagtt aaaactgacc tcttcaaaag cctgcttact taccgcctta gtacgatcta
    25261 attgagtaaa gcgatcaact tggctttgta ttaacgctaa gtgcgccata gattgctcaa
    25321 gcgccgcttg ttttatctct acatcgatag tgaaaatatc ttggtcaatt tgaaacagtg
    25381 catccccctg cttgagggtg tctccttgct taaatagcct ctgggttata attccttcca
    25441 cctgtggacg aatttcagcg ctacgtagtg gccgtactcg accttgcaat tcatcaaaca
    25501 aggtgacttg agttaactca gcagttatgg tggcgatatt ggcggtgttt ggataattaa
    25561 acgcctcgtc agtgctactt ttctcacagg cagtcgtcca gaagcagacc gcagcaaaca
    25621 gccctaaacg ggtaattttt ttaaattcac tagccatata ttatcttcac tcatacctaa
    25681 caggcacagc caatgttcta tctcaattaa gacaaaacct aggcattaaa aattgttggc
    25741 gacagattaa atgagcaaag gtaaaaatag ggtaaacacg caggaagaaa caaatgctag
    25801 ccgagctatt tcttgaataa ctttactcta tatttacccc tgggccacta agctgtaatc
    25861 tcctaggccg aatgaccgac aatagctaaa aattttgatt ggagaacaga gatgatccgt
    25921 gttttattga ttgaagatga ccgtgatctc gccgagacgc tactccaatt aatggagctc
    25981 gcccagatgc ttcccgatca cgtcagtaat ggtattgccg ggctcacatt agcccgcagc
    26041 aatagttatg atgtactggt gattgatgtc ggcttgccta aacttgacgg ctatagtgta
    26101 tgcaaacaac ttagggctag cggaatcgat acaccgatac ttttcttaac cgcgttttcc
    26161 agcatagata ataagcttga aggcttcgct tctggcggtg atgattacct tgctaagccc
    26221 ttcgataatc gagaacttat tgctcgtata acagccttgt caggcagaaa aagtagccat
    26281 gtaaaacggc ttgagatcgc gggcttaatc atgaattgtg agcaacagca agtgtcctat
    26341 caaggacaaa aacttgagct cactccagcc tgctacaccc tgttagaagt actgatgcgc
    26401 gcaagccctg aaatagtcag tcgtcaatca ttagaaaaca agttatgggg cgacgagccg
    26461 ccaagcagta atgtgcttaa agcacatata tattatttgc gccgggcatt aactcaggta
    26521 cagcttgcag aaatgctgta tacctctacg ggaagaggct gggcactgcg cccaagtaac
    26581 acacgatgaa acttcggcaa agcttaagtg ccttattact cgggggcgct ggttttattc
    26641 tattgctact cgtgctcagc tacaccctgt gggcgagaga gaactacttt cgcgccttag
    26701 atacttcttt tagtgtgagt atgcataagg ctcaggagct gattaatcaa caaggatttg
    26761 atagcattgc gcccggatta gcgattattg atgctcagct atttcgtcaa tacaaagcgc
    26821 taccagagag tattaaactc acattttcag aaaaccaact acaggttggc caacattatt
    26881 atgccgatgg tataacccaa agcgataaag ctaaacaccg agatttcttt atctatactg
    26941 ctgagcataa agaacaaggc atttactacc tcgtacagca atatgaagac tctgatagcc
    27001 acagtcactg ggacattgca gatgatcagc tgcaacagat ctgggtggta tcggtcatcg
    27061 ttaccctgct tctagtcatc gtcattttag cttgttttcg ttacttagcg aaacctattt
    27121 acagactcaa tgcttggtcc aagcagttaa acagcaccga tctcaacaag cctattccct
    27181 cttttgaata ccaagagctt gatcgcctcg ccgagcagat cctcaatagc ttgcgggaag
    27241 tcgatagtgt ttatcagcgc gagtcacagt ttctccaata cgccagtcac gagctaagaa
    27301 ccccaattac agtggttaaa agtaatgcag ctttattaga gcaactgatc tcaccaagca
    27361 atatgccgcc attgcagcgt ataatcaggg cgagcaatac catgcatcac ctcacagaaa
    27421 cattattatg gctgacacgt aaagaattag cccaacccaa agcttgtcag tttcaattag
    27481 attctttgat caatgaactc gtagaagaac atgattattt actcaacgga aaaaatgttg
    27541 agttgcaggt caggattgcc gcacaagcgg ttgtattacc gcaaatctta gtcagaattg
    27601 tcgctgcaaa cctcatccgc aatgcgatgc aacatataga tgaaggtgtt atcaacatag
    27661 ctcttggcaa agaagagctg accatagaga ataatggcgt catacttagc gataacacgc
    27721 cccatggtgc taactctgat ggatttggtt taggactgaa gttaattcat caaattagtg
    27781 aacaacaagg ctggtcattt tcgacgtcaa gcaaaccgca gcgctatatt gcaagcatag
    27841 gtttttctag caaaaataac cttatgactc aatgagtaaa cgactagatt aaatggaaaa
    27901 tactacaatg atagagcgta taagtaaggc ttacgatggc gaaatttatg gcatctcctt
    27961 tttcagctat ttcgacaaaa attatcagtt aacagcatcc tcaaaaacac tttgggagac
    28021 cttaattcaa gttgagacgc taacagcgga tcttattgag ccgacattaa acagccacca
    28081 agtccagtac gatagcaata acgctttgat gatcaacaag ggaagcaaag atgcccaaaa
    28141 atggtgccat ctaccatggg cagagctagt cgaaacccta gtcaattggg ttgaacctta
    28201 cgaaaaaaaa taccgctgtt gggctgatga agccagaata gaaaccgaca ctttccgatt
    28261 aatcgccgat catgagacag ccatatacga atgcttcaaa gctgagaaag tcggaatttc
    28321 aggggaaacg attcttttag aatttataag aaagtatgag ccaaaaagaa gttcttgaat
    28381 cacgttagag caacgcagat cctatccatt aaaattgaaa tatcattagg ataaccgcag
    28441 gttaagcgct agccttttct aacaagctta tacgtgtaag ttttcaaacc actgcctcaa
    28501 aatgggtctt accgccggat ttacaaccac tcccatatgg gtcacatcgg gtagcagtgt
    28561 tacctgagcg cttgtgtact gtgaaaacac tggctcaaac tgttcggcaa taaatgcttc
    28621 atccgcggta ccgacgagta ctaataatgg ctgcgttatc gcacagagat cttgcttata
    28681 gttgcgcgga gcgaaggctg tattgaggcg atgggtgtat gacaaggttt ccgtcccatt
    28741 gcggaactct tgtggcatat tgaaatcaat cgcgattaca taatcaaact gatggatgcc
    28801 gatgttattt aacatggtca gcccaacgat tctaagtgta tgaggcgctg cccagccgcc
    28861 tgaatttggc cgcattattg gggcgttata tttaaggtag ggagaaagta aaacataagc
    28921 atcaactcgc tttccgtatc gacttcccgc aaagcgcacc gccagcccgc ctcccgatga
    28981 atggcccgct acaatcagct tacagtcagg atgttccgtt ttaatcagtt caatgaaatc
    29041 ggctaagtca tcttccagtt ggtctatata atcgacatcg ccccgccttt caggtgcttg
    29101 tccatgccca cgaagatccg gcgtatatac ctgagcgagc ccttcggaac tcaaaaaatc
    29161 agtcagagga aacagatact ggctatgcca gcctgagcca tgcaaaaata caacgacctt
    29221 atctgattta gcgtcataat ggcgataggg caatcgcttg ccatctctag tttgatagct
    29281 ttttagttgt ggcagctttg tataatcggt tgccgactta tcagaagcca actcatcgaa
    29341 agctaaattg ttttgggtcg aacttcgttt gctacgctta ccaaacacaa tacagatgga
    29401 ggcaatgctg aaataaatcg ccgcggaaat gaatatgaaa tttaaaacat ctaagaaaac
    29461 cttatccacc caccctccag ttttattttt tgatacaata cgttaagtag ttacatgagc
    29521 aaaagcactt aaacttattc gaatttatca gtttaatcac taacgcctca aacactggca
    29581 cggctttact acagcaatat ttgaggcttg ctagaggatt aaaaaaacga cactcttgtt
    29641 ttaaggtacc gtttaaccca taagtttcca attactgata taaatttgaa tctaccgttt
    29701 tgtcgctaaa tggcacgatc tcaaacttct catcaaactt aactaaagtg ctaacca
//
