Select genomic region:
Overview
1.1
3.1
3.2

### Identified secondary metabolite regions using strictness 'relaxed'

c00001_NZ_CABI.. (original name was: NZ_CABIXZ010000001.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | RRE-containing | 1,596,097 | 1,623,811 |

c00003_NZ_CABI.. (original name was: NZ_CABIXZ010000003.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 3.1 | RRE-containing | 49,321 | 67,397 | exopolysaccharide | Saccharide | 10%
Region 3.2 | ranthipeptide | 134,756 | 160,500 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | RRE-containing | 1,596,097 | 1,623,811 |
Region 3.1 | RRE-containing | 49,321 | 67,397 | exopolysaccharide | Saccharide | 10%
Region 3.2 | ranthipeptide | 134,756 | 160,500 |

No secondary metabolite regions were found in these records:
  c00002_NZ_CABI.. (original name was: NZ_CABIXZ010000002.1)
  c00004_NZ_CABI.. (original name was: NZ_CABIXZ010000004.1)
  c00005_NZ_CABI.. (original name was: NZ_CABIXZ010000005.1)
  c00006_NZ_CABI.. (original name was: NZ_CABIXZ010000006.1)
  c00007_NZ_CABI.. (original name was: NZ_CABIXZ010000007.1)
  c00008_NZ_CABI.. (original name was: NZ_CABIXZ010000008.1)
  c00009_NZ_CABI.. (original name was: NZ_CABIXZ010000009.1)
  c00010_NZ_CABI.. (original name was: NZ_CABIXZ010000010.1)
  c00011_NZ_CABI.. (original name was: NZ_CABIXZ010000011.1)
  c00012_NZ_CABI.. (original name was: NZ_CABIXZ010000012.1)
  c00013_NZ_CABI.. (original name was: NZ_CABIXZ010000013.1)
  c00014_NZ_CABI.. (original name was: NZ_CABIXZ010000014.1)
  c00015_NZ_CABI.. (original name was: NZ_CABIXZ010000015.1)
  c00016_NZ_CABI.. (original name was: NZ_CABIXZ010000016.1)
  c00017_NZ_CABI.. (original name was: NZ_CABIXZ010000017.1)

Compact view
c00001_NZ_CABI.. - Region 1 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,596,097 - 1,623,811 nt. (total: 27,715 nt) Show pHMM detection rules used
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001356.1 |  | 0.17 | RiPP | paeninodin | Paenibacillus dendritiformis C454
BGC0001779.1 |  | 0.17 | RiPP | siamycin | Streptomyces nodosus
BGC0000601.1 |  | 0.16 | RiPP | sporulation killing factor | Bacillus subtilis subsp. subtilis str. 168
BGC0000518.1 |  | 0.16 | RiPP | informatipeptin | Streptomyces viridochromogenes DSM 40736
BGC0000571.1 |  | 0.16 | RiPP | burhizin | Paraburkholderia rhizoxinica HKI 454
BGC0000560.1 |  | 0.15 | RiPP | subtilomycin | Bacillus subtilis
BGC0001229.1 |  | 0.15 | RiPP | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0000592.1 |  | 0.15 | RiPP | microviridin B | Microcystis aeruginosa NIES-298
BGC0000616.1 |  | 0.15 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0001496.1 |  | 0.15 | RiPP | actinokineosin | Actinokineospora spheciospongiae

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001356.1 |  | 0.49 | RiPP | paeninodin | Paenibacillus dendritiformis C454
BGC0001779.1 |  | 0.48 | RiPP | siamycin | Streptomyces nodosus
BGC0000601.1 |  | 0.47 | RiPP | sporulation killing factor | Bacillus subtilis subsp. subtilis str. 168
BGC0000518.1 |  | 0.47 | RiPP | informatipeptin | Streptomyces viridochromogenes DSM 40736
BGC0000571.1 |  | 0.46 | RiPP | burhizin | Paraburkholderia rhizoxinica HKI 454
BGC0000560.1 |  | 0.46 | RiPP | subtilomycin | Bacillus subtilis
BGC0001229.1 |  | 0.46 | RiPP | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0000592.1 |  | 0.46 | RiPP | microviridin B | Microcystis aeruginosa NIES-298
BGC0000616.1 |  | 0.45 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0001496.1 |  | 0.45 | RiPP | actinokineosin | Actinokineospora spheciospongiae

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00003_NZ_CABI.. - Region 1 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 49,321 - 67,397 nt. (total: 18,077 nt) Show pHMM detection rules used
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000813.1 |  | 0.17 | Alkaloid | K-252a | Nonomuraea longicatena
BGC0000699.1 |  | 0.17 | Saccharide | hygromycin A | Streptomyces hygroscopicus subsp. hygroscopicus
BGC0000724.1 |  | 0.17 | Saccharide | streptomycin | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000807.1 |  | 0.17 | Saccharide | phosphonoglycans | Stackebrandtia nassauensis DSM 44728
BGC0001222.1 |  | 0.16 | RiPP | acidocin B | Lactobacillus acidophilus
BGC0000491.1 |  | 0.16 | RiPP | gassericin A | Lactobacillus gasseri
BGC0000825.1 |  | 0.16 | Alkaloid | staurosporine | Streptomyces sp. TP-A0274
BGC0000716.1 |  | 0.16 | Saccharide | spectinomycin | Streptomyces netropsis
BGC0000827.1 |  | 0.16 | Alkaloid | staurosporine | Salinispora arenicola CNS-205
BGC0000616.1 |  | 0.16 | RiPP | amylocyclicin | Bacillus velezensis FZB42

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000813.1 |  | 0.49 | Alkaloid | K-252a | Nonomuraea longicatena
BGC0000699.1 |  | 0.48 | Saccharide | hygromycin A | Streptomyces hygroscopicus subsp. hygroscopicus
BGC0000724.1 |  | 0.48 | Saccharide | streptomycin | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000807.1 |  | 0.47 | Saccharide | phosphonoglycans | Stackebrandtia nassauensis DSM 44728
BGC0001222.1 |  | 0.47 | RiPP | acidocin B | Lactobacillus acidophilus
BGC0000491.1 |  | 0.47 | RiPP | gassericin A | Lactobacillus gasseri
BGC0000825.1 |  | 0.46 | Alkaloid | staurosporine | Streptomyces sp. TP-A0274
BGC0000716.1 |  | 0.46 | Saccharide | spectinomycin | Streptomyces netropsis
BGC0000827.1 |  | 0.46 | Alkaloid | staurosporine | Salinispora arenicola CNS-205
BGC0000616.1 |  | 0.46 | RiPP | amylocyclicin | Bacillus velezensis FZB42

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00003_NZ_CABI.. - Region 2 - ranthipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 134,756 - 160,500 nt. (total: 25,745 nt) Show pHMM detection rules used
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ranthipeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001387.1 |  | 0.18 | Other | nucleocidin | Streptomyces calvus
BGC0001391.1 |  | 0.16 | RiPP | thusin | Bacillus thuringiensis serovar rongseni
BGC0000504.1 |  | 0.16 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000541.1 |  | 0.16 | RiPP | paenicidin A | Paenibacillus polymyxa
BGC0000517.1 |  | 0.16 | RiPP | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0001311.1 |  | 0.16 | RiPP | flavecins | Ruminococcus flavefaciens FD-1
BGC0001494.1 |  | 0.16 | RiPP | acinetodin | Acinetobacter gyllenbergii CIP 110306
BGC0000560.1 |  | 0.16 | RiPP | subtilomycin | Bacillus subtilis
BGC0001210.1 |  | 0.16 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0000554.1 |  | 0.16 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001387.1 |  | 0.49 | Other | nucleocidin | Streptomyces calvus
BGC0001391.1 |  | 0.47 | RiPP | thusin | Bacillus thuringiensis serovar rongseni
BGC0000504.1 |  | 0.47 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000541.1 |  | 0.47 | RiPP | paenicidin A | Paenibacillus polymyxa
BGC0000517.1 |  | 0.47 | RiPP | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0001311.1 |  | 0.47 | RiPP | flavecins | Ruminococcus flavefaciens FD-1
BGC0001494.1 |  | 0.47 | RiPP | acinetodin | Acinetobacter gyllenbergii CIP 110306
BGC0000560.1 |  | 0.47 | RiPP | subtilomycin | Bacillus subtilis
BGC0001210.1 |  | 0.46 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0000554.1 |  | 0.46 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names