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Overview
1.1
1.2
1.3
1.4
1.5
1.6

### Identified secondary metabolite regions using strictness 'relaxed'

NC_015673.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1 | NAPAA | 192,440 | 226,411 |
Region 2 | siderophore | 534,018 | 547,830 | bacillomycin D | Polyketide + NRP:Lipopeptide | 20%
Region 3 | T1PKS | 632,820 | 677,904 |
Region 4 | terpene | 734,019 | 753,836 |
Region 5 | terpene | 1,287,560 | 1,308,768 | SF2575 | Polyketide:Type II + Saccharide:Hybrid/tailoring | 6%
Region 6 | CDPS | 1,573,749 | 1,594,399 | lomaiviticin A / lomaiviticin C / lomaiviticin D / lomaiviticin E | Polyketide:Type II + Saccharide:Hybrid/tailoring | 3%

NC_015673.1 - Region 1 - NAPAA
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 192,440 - 226,411 nt. (total: 33,972 nt) Show pHMM detection rules used
NAPAA: (AMP-binding and PP-binding and TIGR02353)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NAPAA | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000427.1 |  | 0.21 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0001758.1 |  | 0.18 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001641.1 |  | 0.18 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001900.1 |  | 0.18 | NRP | fragin | Burkholderia cenocepacia H111
BGC0001135.1 |  | 0.18 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001615.1 |  | 0.18 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0001128.1 |  | 0.18 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001479.1 |  | 0.18 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001132.1 |  | 0.18 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001844.1 |  | 0.18 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000427.1 |  | 0.54 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0001758.1 |  | 0.50 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001641.1 |  | 0.50 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001900.1 |  | 0.50 | NRP | fragin | Burkholderia cenocepacia H111
BGC0001135.1 |  | 0.50 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001615.1 |  | 0.50 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0001128.1 |  | 0.49 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001479.1 |  | 0.49 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001132.1 |  | 0.49 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001844.1 |  | 0.49 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 192439 - 226411:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_179: X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (25..406): X
  NRPSPredictor2: (unknown)
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      N/A
    Small clusters prediction:
      gly, ala
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAESIGtVvK
    Nearest Stachelhaus code:
      lys
    Stachelhaus code match:
      80% (moderate)

NC_015673.1 - Region 2 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 534,018 - 547,830 nt. (total: 13,813 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000783.1 |  | 0.18 | Saccharide | O-antigen | Xanthomonas oryzae pv. oryzae
BGC0000528.1 |  | 0.16 | RiPP | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0000774.1 |  | 0.15 | Saccharide | lipopolysaccharide | Xanthomonas campestris pv. campestris
BGC0001789.1 |  | 0.10 | RiPP | suicin 90-1330 | Streptococcus suis
BGC0000537.1 |  | 0.10 | RiPP | nisin U | Streptococcus uberis
BGC0000310.1 |  | 0.07 | NRP | bacitracin | Bacillus licheniformis
BGC0000349.1 |  | 0.07 | NRP | erythrochelin | Saccharopolyspora erythraea NRRL 2338
BGC0001669.1 |  | 0.07 | RiPP | microvionin | Microbacterium arborescens
BGC0000874.1 |  | 0.07 | Other | blasticidin S | Streptomyces griseochromogenes
BGC0001524.1 |  | 0.07 | NRP, Polyketide | barnesin A | Sulfurospirillum barnesii SES-3

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000783.1 |  | 0.49 | Saccharide | O-antigen | Xanthomonas oryzae pv. oryzae
BGC0000528.1 |  | 0.46 | RiPP | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0000774.1 |  | 0.46 | Saccharide | lipopolysaccharide | Xanthomonas campestris pv. campestris
BGC0001789.1 |  | 0.36 | RiPP | suicin 90-1330 | Streptococcus suis
BGC0000537.1 |  | 0.36 | RiPP | nisin U | Streptococcus uberis
BGC0000310.1 |  | 0.29 | NRP | bacitracin | Bacillus licheniformis
BGC0000349.1 |  | 0.28 | NRP | erythrochelin | Saccharopolyspora erythraea NRRL 2338
BGC0001669.1 |  | 0.28 | RiPP | microvionin | Microbacterium arborescens
BGC0000874.1 |  | 0.27 | Other | blasticidin S | Streptomyces griseochromogenes
BGC0001524.1 |  | 0.27 | NRP, Polyketide | barnesin A | Sulfurospirillum barnesii SES-3

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_015673.1 - Region 3 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 632,820 - 677,904 nt. (total: 45,085 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T1PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001831.1 |  | 0.24 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0001281.1 |  | 0.22 | Polyketide | ustilagic acid | Ustilago maydis 521
BGC0001897.1 |  | 0.22 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0001162.1 |  | 0.21 | Polyketide | 1-heptadecene | Moorea producens JHB
BGC0001161.1 |  | 0.21 | Polyketide | 1-heptadecene | Moorea bouillonii PNG
BGC0001163.1 |  | 0.21 | Polyketide | 1-heptadecene | Moorea producens 3L
BGC0000044.1 |  | 0.20 | Polyketide | dawenol | Stigmatella aurantiaca DW4/3-1
BGC0001273.1 |  | 0.19 | Polyketide | asperlactone | Aspergillus ochraceus
BGC0001276.1 |  | 0.19 | Polyketide | 6-methylsalicyclic acid | Aspergillus terreus
BGC0001275.1 |  | 0.19 | Polyketide | 6-methylsalicyclic acid | Glarea lozoyensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001831.1 |  | 0.57 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0001281.1 |  | 0.55 | Polyketide | ustilagic acid | Ustilago maydis 521
BGC0001897.1 |  | 0.55 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0001162.1 |  | 0.54 | Polyketide | 1-heptadecene | Moorea producens JHB
BGC0001161.1 |  | 0.54 | Polyketide | 1-heptadecene | Moorea bouillonii PNG
BGC0001163.1 |  | 0.54 | Polyketide | 1-heptadecene | Moorea producens 3L
BGC0000044.1 |  | 0.52 | Polyketide | dawenol | Stigmatella aurantiaca DW4/3-1
BGC0001273.1 |  | 0.51 | Polyketide | asperlactone | Aspergillus ochraceus
BGC0001276.1 |  | 0.51 | Polyketide | 6-methylsalicyclic acid | Aspergillus terreus
BGC0001275.1 |  | 0.51 | Polyketide | 6-methylsalicyclic acid | Glarea lozoyensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 632819 - 677904:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (mal)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_568: pk
  CAL_domain (68..526): pk
  minowa: Acetyl-CoA
  Prediction, score:
    Acetyl-CoA: 17.5
    fatty_acid: 15.8
    AHBA: 5.8
    NH2: 5.4
    shikimic_acid: 0.0
ctg1_569: mal
  PKS_AT (704..1006): mal
  ATSignature: Malonyl-CoA
  Top 3 matches:
    Malonyl-CoA: 62.5%
    Methylmalonyl-CoA: 54.2%
  minowa: fatty_acid
  Prediction, score:
    fatty_acid: 112.9
    Malonyl-CoA: 80.3
    Methylmalonyl-CoA: 79.8
    Methoxymalonyl-CoA: 74.4
    Propionyl-CoA: 57.0
    Ethylmalonyl-CoA: 55.9
    Isobutyryl-CoA: 51.0
    2-Methylbutyryl-CoA: 44.9
    Acetyl-CoA: 33.9
    trans-1,2-CPDA: 32.5
    CHC-CoA: 27.9
    Benzoyl-CoA: 8.9
    inactive: 0.0
    3-Methylbutyryl-CoA: 0.0
ctg1_571: X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (70..470): X
  NRPSPredictor2: (unknown)
  SVM prediction details:
    NOTE: outside applicability domain
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      hsWiVSfVvK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      50% (weak)

NC_015673.1 - Region 4 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 734,019 - 753,836 nt. (total: 19,818 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000650.1 |  | 0.28 | Terpene | carotenoid | Algoriphagus sp. KK10202C
BGC0000637.1 |  | 0.22 | Terpene | carotenoid | Corynebacterium glutamicum
BGC0000636.1 |  | 0.21 | Terpene | carotenoid | Brevibacterium linens
BGC0000644.1 |  | 0.19 | Terpene | carotenoid | Dietzia sp. CQ4
BGC0000868.1 |  | 0.16 | Other | teichuronic acid | Bacillus subtilis subsp. subtilis str. 168
BGC0000786.1 |  | 0.15 | Saccharide | O-antigen | Edwardsiella ictaluri 93-146
BGC0000725.1 |  | 0.15 | Saccharide | alginate | Pseudomonas aeruginosa PAO1
BGC0000782.1 |  | 0.15 | Saccharide | O-antigen | Burkholderia pseudomallei 1026b
BGC0000777.1 |  | 0.15 | Saccharide | lipopolysaccharide | Escherichia coli
BGC0001411.1 |  | 0.15 | Saccharide | polysaccharide B | Bacteroides fragilis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000650.1 |  | 0.61 | Terpene | carotenoid | Algoriphagus sp. KK10202C
BGC0000637.1 |  | 0.55 | Terpene | carotenoid | Corynebacterium glutamicum
BGC0000636.1 |  | 0.53 | Terpene | carotenoid | Brevibacterium linens
BGC0000644.1 |  | 0.51 | Terpene | carotenoid | Dietzia sp. CQ4
BGC0000868.1 |  | 0.47 | Other | teichuronic acid | Bacillus subtilis subsp. subtilis str. 168
BGC0000786.1 |  | 0.45 | Saccharide | O-antigen | Edwardsiella ictaluri 93-146
BGC0000725.1 |  | 0.45 | Saccharide | alginate | Pseudomonas aeruginosa PAO1
BGC0000782.1 |  | 0.45 | Saccharide | O-antigen | Burkholderia pseudomallei 1026b
BGC0000777.1 |  | 0.45 | Saccharide | lipopolysaccharide | Escherichia coli
BGC0001411.1 |  | 0.44 | Saccharide | polysaccharide B | Bacteroides fragilis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_015673.1 - Region 5 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,287,560 - 1,308,768 nt. (total: 21,209 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000563.1 |  | 0.17 | RiPP | venezuelin | Streptomyces venezuelae ATCC 10712
BGC0001660.1 |  | 0.17 | RiPP | mathermycin | Marinactinospora thermotolerans
BGC0001579.1 |  | 0.17 | RiPP | duramycin | Streptomyces cinnamoneus
BGC0000521.1 |  | 0.16 | RiPP | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0000539.1 |  | 0.16 | RiPP | nukacin ISK-1 | Staphylococcus warneri
BGC0001551.1 |  | 0.16 | RiPP | citrulassin E | Streptomyces glaucescens
BGC0000496.1 |  | 0.16 | RiPP | AmfS | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000626.1 |  | 0.16 | RiPP | thuricin | Bacillus thuringiensis
BGC0000918.1 |  | 0.16 | Other | ochronotic pigment | Streptomyces avermitilis
BGC0000501.1 |  | 0.15 | RiPP | catenulipeptin | Catenulispora acidiphila DSM 44928

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000563.1 |  | 0.49 | RiPP | venezuelin | Streptomyces venezuelae ATCC 10712
BGC0001660.1 |  | 0.48 | RiPP | mathermycin | Marinactinospora thermotolerans
BGC0001579.1 |  | 0.48 | RiPP | duramycin | Streptomyces cinnamoneus
BGC0000521.1 |  | 0.47 | RiPP | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0000539.1 |  | 0.47 | RiPP | nukacin ISK-1 | Staphylococcus warneri
BGC0001551.1 |  | 0.47 | RiPP | citrulassin E | Streptomyces glaucescens
BGC0000496.1 |  | 0.46 | RiPP | AmfS | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000626.1 |  | 0.46 | RiPP | thuricin | Bacillus thuringiensis
BGC0000918.1 |  | 0.46 | Other | ochronotic pigment | Streptomyces avermitilis
BGC0000501.1 |  | 0.46 | RiPP | catenulipeptin | Catenulispora acidiphila DSM 44928

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
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Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_015673.1 - Region 6 - CDPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
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Location: 1,573,749 - 1,594,399 nt. (total: 20,651 nt) Show pHMM detection rules used
CDPS: (CDPS or cycdipepsynth)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | CDPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001514.1 |  | 0.19 | Other | aristeromycin | Streptomyces citricolor
BGC0001782.1 |  | 0.15 | Other | spiroindimicin A, spiroindimicin B, spiroindimicin C, spiroindimicin D, indimicin A, indimicin B, indimicin C, indimicin D, indimicin E, lynamicin A, lynamicin D, lynamicin F, lynamicin G | Streptomyces sp. SCSIO 03032
BGC0001315.1 |  | 0.13 | Terpene | cucurbitacin | Cucumis sativus
BGC0001441.1 |  | 0.10 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0001730.1 |  | 0.09 | Polyketide | paramagnetoquinone 1, paramagnetoquinone 2 | Actinoallomurus sp.
BGC0000653.1 |  | 0.09 | Terpene | pentalenolactone | Streptomyces arenae
BGC0001940.1 |  | 0.08 | Polyketide | pyxidicycline A, pyxidicycline B | Pyxidicoccus fallax
BGC0000264.1 |  | 0.08 | Polyketide | resistomycin, resistoflavine | Streptomyces resistomycificus
BGC0000158.1 |  | 0.07 | Polyketide | tautomycetin | Streptomyces griseochromogenes
BGC0000219.1 |  | 0.07 | Polyketide, Saccharide | elloramycin | Streptomyces olivaceus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001514.1 |  | 0.50 | Other | aristeromycin | Streptomyces citricolor
BGC0001782.1 |  | 0.45 | Other | spiroindimicin A, spiroindimicin B, spiroindimicin C, spiroindimicin D, indimicin A, indimicin B, indimicin C, indimicin D, indimicin E, lynamicin A, lynamicin D, lynamicin F, lynamicin G | Streptomyces sp. SCSIO 03032
BGC0001315.1 |  | 0.42 | Terpene | cucurbitacin | Cucumis sativus
BGC0001441.1 |  | 0.36 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0001730.1 |  | 0.34 | Polyketide | paramagnetoquinone 1, paramagnetoquinone 2 | Actinoallomurus sp.
BGC0000653.1 |  | 0.33 | Terpene | pentalenolactone | Streptomyces arenae
BGC0001940.1 |  | 0.32 | Polyketide | pyxidicycline A, pyxidicycline B | Pyxidicoccus fallax
BGC0000264.1 |  | 0.30 | Polyketide | resistomycin, resistoflavine | Streptomyces resistomycificus
BGC0000158.1 |  | 0.29 | Polyketide | tautomycetin | Streptomyces griseochromogenes
BGC0000219.1 |  | 0.27 | Polyketide, Saccharide | elloramycin | Streptomyces olivaceus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names