LOCUS       c00050_NZ_BBIR..       15151 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_BBIR01000109.1 Pseudomonas japonica NBRC 103040 = DSM 22348
            strain NBRC 103040, whole genome shotgun sequence.
ACCESSION   NZ_BBIR01000109
VERSION     NZ_BBIR01000109
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 16:47:01
            Original ID  :: NZ_BBIR01000109.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15151
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15151
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[11001:14427](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      11002..14427
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..15151
                     /SMILES="NC(CC(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15151
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             3..4394
                     /locus_tag="ctg50_1"
                     /transl_table=11
                     /translation="TPAVTAVTDTVDTSTVTLTATPNVAEGGVVTYTATVSAPVTLAPL
                     VITLANNQTITIAVGQTVGTVNFTAPNNVYTANPTLTNSITGVSGGNYEKLDATGTTST
                     TITDGPIDTTNVTLTATASVAEGGQYSYTATLTNLAASPVTVTLSNGLTIVIPKDALSA
                     TILVNAPTDTPYIDAGSTSAKITGASGGGFENLTFGTNTVITQITDTVTPTTVSITGTT
                     SVAEGGTATYTINLSNPSQSAVTVKLSYSGTAANGSDYTGTTTVTIPAGASKVDFSIPT
                     IKDAVTEGTEQFTVKVDSASGGNFESLVVSGTAGSVTTQIFEPAPILDLDGNNSSGKTG
                     ADYQVTFTEGQPGTGVSIGDVDLSITDIDSTNLTGATVTLTNRLAGDALNLGNSVNGIS
                     INAVNTNDKVVLTLSGNASIADYIQRLKNITFINTSDDPSSTPRTITVTVTDGVNTSNV
                     ATTTVNVVPVNDAPTAAGGEITGTEDTDLALTWTSLGVSDLDNAASALGITITQLPVNG
                     TLQYKDGATWKTLTAADAGKVFSKADIDAGNLKFVPLANQSGITANGGTGVGNQQADYA
                     QLKYKPYDGQALGNEATLKIDITPVADKPTLTIGSNAVASIGLTKEIYTGLSGLGTNGN
                     GADAATLKSVIDAAAGKAQSTAIATNVTAADVTAGIASKTSGLMYMEAGSTYKFTGVGD
                     DSLAVVVGGRDVASTTWGAGGQLNGTFTPAKSGYYTVEIYHYNQAGPGSYDVNVSVNGA
                     AAIDVSQVGTALYPTAAALAAAGVTVADFHGSNGKGYYDGYKLNEGGENGTVKLVGISA
                     ALTDTDGSETLSVKLGGIPVGSVISDNAGHSVTVGATAVDVSGWNLNNLSIKPPAYYSG
                     TFNVAVSATSTETINGSSVSTPDTIKVTVYGDTYAVATNATAESDTWTGTDGNDIIAAD
                     INGLHVVAGQSYNLAFIVDTSGSMKSDGVDAAQKALQSVFTTLSNSVQGASSGTVNILL
                     VDFATQVKSTVSVNLGDSGALQTLKNALTTMSSGGGTNYEDAFKTTANWFQNLVSAGNT
                     GKNQTFFITDGEPTYYQSGERDNPTLVKGSGSKAEITMDNYLTSIGYKLGQVVNVNVDS
                     NNRLTIDSSGNLNLYKNGNYYSSLSGTLHAQGDGTYELSSLAGQGNYADSDTISNSKSA
                     FAVLKALSPTVEAIGINSGVDVNDLKPYDSDGVPQTNIDPSNLANAILGHTEATLPGND
                     TVNANDGNDIVFGDLIMFSTVSGNGVEALQSYVAKQTGLDASAVDSKTMHQYITEHVSE
                     FDVSRTSDGDDKLYGGQGNDILFGQGGNDLLDGGAGNDMLLGGSGNDTLLGGEGNDLLF
                     GGKGNDTLTGGSGADTFIWKAGDTGNDIIKDFKAAEGDRLDLSDLLQGEKASTIDNYLK
                     ITTANGDSTLQVSSEGKLNAAGGIANADVTIKLEGVNWSNTTINSLISGADPTIKIDHN
                     NS"
     PFAM_domain     669..893
                     /aSDomain="Calx-beta"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03160.16"
                     /description="Calx-beta domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg50_1_0001"
                     /evalue="5.30E-07"
                     /label="ctg50_1"
                     /locus_tag="ctg50_1"
                     /protein_end="297"
                     /protein_start="222"
                     /score="29.8"
                     /tool="antismash"
                     /translation="SVAEGGTATYTINLSNPSQSAVTVKLSYSGTAANGSDYTGTTTVT
                     IPAGASKVDFSIPTIKDAVTEGTEQFTVKV"
     PFAM_domain     1368..1661
                     /aSDomain="Cadherin_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16184.7"
                     /description="Cadherin-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg50_1_0002"
                     /evalue="1.90E-08"
                     /label="ctg50_1"
                     /locus_tag="ctg50_1"
                     /protein_end="553"
                     /protein_start="455"
                     /score="34.3"
                     /tool="antismash"
                     /translation="SNVATTTVNVVPVNDAPTAAGGEITGTEDTDLALTWTSLGVSDLD
                     NAASALGITITQLPVNGTLQYKDGATWKTLTAADAGKVFSKADIDAGNLKFVP"
     PFAM_domain     2832..3182
                     /aSDomain="VWA_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13519.8"
                     /description="von Willebrand factor type A domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg50_1_0003"
                     /evalue="2.80E-11"
                     /label="ctg50_1"
                     /locus_tag="ctg50_1"
                     /protein_end="1060"
                     /protein_start="943"
                     /score="44.1"
                     /tool="antismash"
                     /translation="LAFIVDTSGSMKSDGVDAAQKALQSVFTTLSNSVQGASSGTVNIL
                     LVDFATQVKSTVSVNLGDSGALQTLKNALTTMSSGGGTNYEDAFKTTANWFQNLVSAGN
                     TGKNQTFFITDGE"
     PFAM_domain     3669..3719
                     /aSDomain="HemolysinCabind"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00353.21"
                     /description="RTX calcium-binding nonapeptide repeat (4
                     copies)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg50_1_0004"
                     /evalue="9.40E-03"
                     /label="ctg50_1"
                     /locus_tag="ctg50_1"
                     /protein_end="1239"
                     /protein_start="1222"
                     /score="16.0"
                     /tool="antismash"
                     /translation="GNDTVNANDGNDIVFGD"
     PFAM_domain     3873..3974
                     /aSDomain="HemolysinCabind"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00353.21"
                     /description="RTX calcium-binding nonapeptide repeat (4
                     copies)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg50_1_0005"
                     /evalue="1.00E-09"
                     /label="ctg50_1"
                     /locus_tag="ctg50_1"
                     /protein_end="1324"
                     /protein_start="1290"
                     /score="38.2"
                     /tool="antismash"
                     /translation="SDGDDKLYGGQGNDILFGQGGNDLLDGGAGNDML"
     PFAM_domain     3978..4079
                     /aSDomain="HemolysinCabind"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00353.21"
                     /description="RTX calcium-binding nonapeptide repeat (4
                     copies)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg50_1_0006"
                     /evalue="4.40E-11"
                     /label="ctg50_1"
                     /locus_tag="ctg50_1"
                     /protein_end="1359"
                     /protein_start="1325"
                     /score="42.6"
                     /tool="antismash"
                     /translation="GGSGNDTLLGGEGNDLLFGGKGNDTLTGGSGADT"
     aSDomain        4110..4352
                     /aSDomain="TIGR03661"
                     /aSTool="tigrfam"
                     /description="T1SS_VCA0849: type I secretion C-terminal
                     target domain (VC_A0849 subclass)"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg50_1_0001"
                     /evalue="5.00E-20"
                     /identifier="TIGR03661"
                     /label="ctg50_1"
                     /locus_tag="ctg50_1"
                     /protein_end="1450"
                     /protein_start="1369"
                     /score="70.5"
                     /tool="antismash"
                     /translation="DIIKDFKAAEGDRLDLSDLLQGEKASTIDNYLKITTANGDSTLQV
                     SSEGKLNAAGGIANADVTIKLEGVNWSNTTINSLIS"
     CDS             4642..4983
                     /locus_tag="ctg50_2"
                     /transl_table=11
                     /translation="MFYVQRDAEGQLLRVEAAAFAEATEILPADHAEVLEWFADDVVEN
                     SLKQLKQSDLDMIRVLEDLIEVLTTKGVISITDLPPGAQAKLLNRNTARAALGGLNNLI
                     DDEEVGGLI"
     CDS             complement(5014..6945)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:diguanylate cyclase (Score: 80.1; E-value:
                     3.8e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_3"
                     /transl_table=11
                     /translation="MSLFKQLLLAICLFLVVAFSGSFMVSLESSRSQYVNQLRSHAQDA
                     ATALALSLTPNLDDPAMVELLVSSIFDSGYYASIRVVDLGSSALLVERHADPDPGGVPQ
                     WFIQLIGLEAAGGDAIVMRGWQQAARVEVVSHPMFALAKLWQSALGSLGWLLLCGGLSA
                     VAGALLLRRQLKPLDYMVEQSHAIARREFLSLPDLPRTPELRRVVQAMNQMVEKLKALY
                     QEQAERSEKLRVESYQDSLTGLANRRYFEMQLNARVSNLEEAREGYLLLLRVQDLAGLN
                     QRLGGQRTDQLLRAVGQQLQRICSAYPETNNLITRSRGGEFAVLAPGMTHDDAIALAQA
                     LEVGLRGISDVTPSVCIGLAPFSPGDEPKALLQLADEALARAQSQPEPSWVCLEQGSAS
                     QASDTHRQWHNLLDEALNQGRFRLFFQPVVDCNQLDRVLHYKVLSRLVDDNGETIAAGR
                     FLPALERFGWSSRLDLVMLEKVLKQMHGHDQALALNLSATTVVDPASQQRVFELLAQHA
                     VLGPRLTLEIAEEQLPEQAVLEQLTRRLRVLGFSLSLQHFGGRFSMIGNLAHLGLAYLK
                     IDGSYIRAIDQEQHKRLFIEAVQRAAHSIDLPLIAERVETEGELQVLQEMQIQGVQGRL
                     VGEPAPWA"
     PFAM_domain     complement(5029..5712)
                     /aSDomain="EAL"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00563.22"
                     /description="EAL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg50_3_0010"
                     /evalue="6.40E-53"
                     /label="ctg50_3"
                     /locus_tag="ctg50_3"
                     /protein_end="639"
                     /protein_start="411"
                     /score="179.7"
                     /tool="antismash"
                     /translation="LDEALNQGRFRLFFQPVVDCNQLDRVLHYKVLSRLVDDNGETIAA
                     GRFLPALERFGWSSRLDLVMLEKVLKQMHGHDQALALNLSATTVVDPASQQRVFELLAQ
                     HAVLGPRLTLEIAEEQLPEQAVLEQLTRRLRVLGFSLSLQHFGGRFSMIGNLAHLGLAY
                     LKIDGSYIRAIDQEQHKRLFIEAVQRAAHSIDLPLIAERVETEGELQVLQEMQIQGVQG
                     RLVGEP"
     PFAM_domain     complement(5791..6237)
                     /aSDomain="GGDEF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00990.23"
                     /description="Diguanylate cyclase, GGDEF domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg50_3_0009"
                     /evalue="5.80E-21"
                     /label="ctg50_3"
                     /locus_tag="ctg50_3"
                     /protein_end="385"
                     /protein_start="236"
                     /score="75.0"
                     /tool="antismash"
                     /translation="YQDSLTGLANRRYFEMQLNARVSNLEEAREGYLLLLRVQDLAGLN
                     QRLGGQRTDQLLRAVGQQLQRICSAYPETNNLITRSRGGEFAVLAPGMTHDDAIALAQA
                     LEVGLRGISDVTPSVCIGLAPFSPGDEPKALLQLADEALARAQSQ"
     aSDomain        complement(5791..6249)
                     /aSDomain="TIGR00254"
                     /aSTool="tigrfam"
                     /description="GGDEF: diguanylate cyclase (GGDEF) domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg50_3_0002"
                     /evalue="2.00E-15"
                     /identifier="TIGR00254"
                     /label="ctg50_3"
                     /locus_tag="ctg50_3"
                     /protein_end="385"
                     /protein_start="232"
                     /score="54.8"
                     /tool="antismash"
                     /translation="RVESYQDSLTGLANRRYFEMQLNARVSNLEEAREGYLLLLRVQDL
                     AGLNQRLGGQRTDQLLRAVGQQLQRICSAYPETNNLITRSRGGEFAVLAPGMTHDDAIA
                     LAQALEVGLRGISDVTPSVCIGLAPFSPGDEPKALLQLADEALARAQSQ"
     PFAM_domain     complement(6289..6444)
                     /aSDomain="HAMP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00672.27"
                     /description="HAMP domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg50_3_0008"
                     /evalue="6.30E-06"
                     /label="ctg50_3"
                     /locus_tag="ctg50_3"
                     /protein_end="219"
                     /protein_start="167"
                     /score="26.6"
                     /tool="antismash"
                     /translation="LLLRRQLKPLDYMVEQSHAIARREFLSLPDLPRTPELRRVVQAMN
                     QMVEKLK"
     PFAM_domain     complement(6511..6879)
                     /aSDomain="LapD_MoxY_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16448.7"
                     /description="LapD/MoxY periplasmic domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg50_3_0007"
                     /evalue="2.60E-38"
                     /label="ctg50_3"
                     /locus_tag="ctg50_3"
                     /protein_end="145"
                     /protein_start="22"
                     /score="130.7"
                     /tool="antismash"
                     /translation="FMVSLESSRSQYVNQLRSHAQDAATALALSLTPNLDDPAMVELLV
                     SSIFDSGYYASIRVVDLGSSALLVERHADPDPGGVPQWFIQLIGLEAAGGDAIVMRGWQ
                     QAARVEVVSHPMFALAKLW"
     CDS             complement(6955..7647)
                     /locus_tag="ctg50_4"
                     /transl_table=11
                     /translation="LAIRWTLHLLLRRASLALLLGLALLGGLRADWDFSQISRKAAALY
                     GPLGAGQQRIDAWQQLLATQKQLGEAERLQVVNQFFNRQLRYEEDIDLWHEVDYWATPI
                     QSLIKGAGDCEDYAIAKYFSLRRLGIPADKLRITYVKALRQNRAHMVLTYYSSPDAMPL
                     VLDSLIDAIKPASQRTDLLPVYAFNGEGLWLTGAAGNKKVGDTKRLSRWQDLLKKMQAE
                     GFPAEPVY"
     PFAM_domain     complement(7120..7443)
                     /aSDomain="Peptidase_C93"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06035.13"
                     /description="Bacterial transglutaminase-like cysteine
                     proteinase BTLCP"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg50_4_0011"
                     /evalue="3.60E-17"
                     /label="ctg50_4"
                     /locus_tag="ctg50_4"
                     /protein_end="176"
                     /protein_start="68"
                     /score="62.8"
                     /tool="antismash"
                     /translation="GEAERLQVVNQFFNRQLRYEEDIDLWHEVDYWATPIQSLIKGAGD
                     CEDYAIAKYFSLRRLGIPADKLRITYVKALRQNRAHMVLTYYSSPDAMPLVLDSLIDAI
                     KPAS"
     CDS             7958..8647
                     /gene_functions="regulatory (smcogs) SMCOG1071:GntR family
                     transcriptional regulator (Score: 164.2; E-value: 6e-50)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg50_5"
                     /transl_table=11
                     /translation="VAGKTKLLSNILGDEQVPAHLARSVIEERLRSAILDGRLAPGMAL
                     RQQELATLFGVSRMPVREALRQLEAQSLLEVVPHKGAVVAPLIGEDAVDTYELRVMLET
                     EALRQSIPLLGPDDIALARSYIHQLENETRHSEIGRLNRLFHMTLYSKANNTKLLRLID
                     NELLQEERFLRFHLSSMGLGKLTQDDHNGLTDAANDKDIEQAVVILHRHLNNAMRTIRD
                     YLSRKDK"
     PFAM_domain     8030..8209
                     /aSDomain="GntR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00392.23"
                     /description="Bacterial regulatory proteins, gntR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg50_5_0012"
                     /evalue="5.90E-20"
                     /label="ctg50_5"
                     /locus_tag="ctg50_5"
                     /protein_end="84"
                     /protein_start="24"
                     /score="70.8"
                     /tool="antismash"
                     /translation="VIEERLRSAILDGRLAPGMALRQQELATLFGVSRMPVREALRQLE
                     AQSLLEVVPHKGAVV"
     PFAM_domain     8237..8599
                     /aSDomain="FCD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07729.14"
                     /description="FCD domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg50_5_0013"
                     /evalue="1.20E-17"
                     /label="ctg50_5"
                     /locus_tag="ctg50_5"
                     /protein_end="214"
                     /protein_start="93"
                     /score="64.5"
                     /tool="antismash"
                     /translation="DTYELRVMLETEALRQSIPLLGPDDIALARSYIHQLENETRHSEI
                     GRLNRLFHMTLYSKANNTKLLRLIDNELLQEERFLRFHLSSMGLGKLTQDDHNGLTDAA
                     NDKDIEQAVVILHRHLN"
     CDS             9285..10061
                     /locus_tag="ctg50_6"
                     /transl_table=11
                     /translation="MNPLQALLHEKKSELAKHPIFAEIDSLPVLRRFMETHVYAVWDFM
                     SLTKRLQQELTCIQLPWLPPKDPKAARLINEIVLGEESDDRLDHDHYSHFELYLDAMRE
                     VGACTASVERFVALQRDGLHHRAALTSAGASEAARHFVEQTLDIALNAPAHAVAAAFLH
                     GRESVIPTMFQRILDDWGITGSQAPTFRYYLQRHIEVDSEDHGPAAGQLLARLVGDDPQ
                     REREVYEAAIAAVESRLAFWDRLRVSMHQEIAEVNV"
     PFAM_domain     9327..10016
                     /aSDomain="DUF3050"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11251.10"
                     /description="Protein of unknown function (DUF3050)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg50_6_0014"
                     /evalue="4.40E-89"
                     /label="ctg50_6"
                     /locus_tag="ctg50_6"
                     /protein_end="244"
                     /protein_start="14"
                     /score="298.2"
                     /tool="antismash"
                     /translation="LAKHPIFAEIDSLPVLRRFMETHVYAVWDFMSLTKRLQQELTCIQ
                     LPWLPPKDPKAARLINEIVLGEESDDRLDHDHYSHFELYLDAMREVGACTASVERFVAL
                     QRDGLHHRAALTSAGASEAARHFVEQTLDIALNAPAHAVAAAFLHGRESVIPTMFQRIL
                     DDWGITGSQAPTFRYYLQRHIEVDSEDHGPAAGQLLARLVGDDPQREREVYEAAIAAVE
                     SRLAFWDR"
     CDS             10058..11005
                     /locus_tag="ctg50_7"
                     /transl_table=11
                     /translation="MNDLDYQSFAEAWEGRATIRTRPRRLVEDDQRLIFPLSRQSLVLT
                     ATFQRECPHLCDFVLVQSLYKFINDVVIFETEIVDRTARAIAKDRFAVRFPFACRYDAM
                     TVVVDEDYHALVAMDFMQQTVALTGVQPLALPREIELSRAIPAALSLAPEHLRDAVELI
                     CVGIAENTLTNDVAAFARDDSVKGSIKGLMADHLLDEGRHSTFWARLTRIYWSQASAQD
                     RQCIAGILPVFLRHYLTSEIQQAFDLQLIDALDVPPAVTAALRAEASGMDWPIGPRHPL
                     LGNILRFFRNSSLLDTPCVQEALIDYLPLSRTAP"
     PFAM_domain     10127..10855
                     /aSDomain="AurF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11583.10"
                     /description="P-aminobenzoate N-oxygenase AurF"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg50_7_0015"
                     /evalue="3.20E-19"
                     /label="ctg50_7"
                     /locus_tag="ctg50_7"
                     /protein_end="266"
                     /protein_start="23"
                     /score="69.3"
                     /tool="antismash"
                     /translation="RRLVEDDQRLIFPLSRQSLVLTATFQRECPHLCDFVLVQSLYKFI
                     NDVVIFETEIVDRTARAIAKDRFAVRFPFACRYDAMTVVVDEDYHALVAMDFMQQTVAL
                     TGVQPLALPREIELSRAIPAALSLAPEHLRDAVELICVGIAENTLTNDVAAFARDDSVK
                     GSIKGLMADHLLDEGRHSTFWARLTRIYWSQASAQDRQCIAGILPVFLRHYLTSEIQQA
                     FDLQLIDALDVPPAVTAALRA"
     CDS             11002..14427
                     /NRPS_PKS="Domain: AMP-binding (189-576). E-value: 2.4e-87.
                     Score: 285.0. Matches aSDomain:
                     nrpspksdomains_ctg50_8_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (681-748). E-value: 1.8e-16.
                     Score: 52.3. Matches aSDomain:
                     nrpspksdomains_ctg50_8_PP-binding.1"
                     /NRPS_PKS="Domain: TD (785-1024). E-value: 6.6e-55. Score:
                     177.8. Matches aSDomain: nrpspksdomains_ctg50_8_TD.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     291.1; E-value: 2.1e-88)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_8"
                     /sec_met_domain="AMP-binding (E-value: 2e-94, bitscore:
                     305.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.9e-17, bitscore:
                     52.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 5.4e-52, bitscore:
                     165.6, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRLDILLAGNSPALGQLFEELEQHGHTLHHAKATQELTAHPSTR
                     PDLVIEDGSVDLPDLGAGIVLSLRVGSGDTLVAELPEVELLYWAGSARAQRLIDRQPLE
                     KEASGNGQELRMTALSALRERVALHVSRFSRNPEHFRERETIGPMCQAHEHSLPWLERL
                     AWLHRFNRDAQDGLLQASESALIERLEQSLARHARLPALNIQGRRISYAQLQGQALAIQ
                     AQLLPLLSSDRPLVAVCLPKSPALYASLLAVLGCSAVYLPLDPATPSERLAFILKNAGA
                     ALLIHDGRIREWDRSIPDLDLSQLPEPVAAPSTRLLRRLPGADEPCVAIYTSGTTGQPK
                     GVLLSQRNLSHFQVWYSGHVQLTAQSRVLQFSTINFDASLLDILPTWVAGAELVVPDEE
                     QRRDPARLEALIREQEVSHAFLPPALLSLLKLEGTGLEHLVSGGDVCEPDVIERLAGRC
                     RFHNIYGPTETTVLATTRVFANGDNPRNLGTPISNARVFLLDEALQPVPERSVGELYIG
                     GPGVGLGYLNNPELSRERFISLELPDGECLRLYRSGDLGQWTADGIEICGRRDNQVKIR
                     GFRVEPEEIEHCLRASRLFAQVVVVIDEQRRVLSFLAQPRQTAALERLRAHAEQNLPDY
                     MRPLLYQELPQMPCTANGKVDRRALLSLPVTLAGARQRLAPANALEERLLTLWSELLEL
                     PAEDISTDDSFFNLGGHSILLSRLLLALRDGFGRGISINRFIETPTLQRLSALLSGETT
                     TVGALHPQALSDADRALELRVLPLEQLGDVHRVIVTGANSFLGVHIVEALLAWGASEVA
                     CLVRRGEGVGAAERFARALSDNRIGALDWRRVRVLEADLRMPRFGLSDTEYEDLDRRFG
                     SLVHNAAQVNHVLDYPALAADNVEPLFECLRLCEGRSKKIFNFVSTLSACSARDAQGRV
                     LEQPPAATPPLYIRNGYNLSKWVGERILQRAREQGVRVNLFRPGNITFDSRSGVSQPHK
                     NRLMLMLKGSLQLGQVPALDLEFDLMPVDFLARFIAFHASRHHPAQAVFNLHNPQPLRW
                     AGYVEAFRKDGRAFELVSVAQWQHALQRVDRDNALFEVLGFYLDGFEEDIGDTTLIDHA
                     NAREGVQRMGEDYPEKSPALLERGRQYLREIRFI"
     aSDomain        11569..12729
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg50_8_AMP-binding.1"
                     /evalue="2.40E-87"
                     /label="ctg50_8_AMP-binding.1"
                     /locus_tag="ctg50_8"
                     /protein_end="576"
                     /protein_start="189"
                     /score="285.0"
                     /specificity="consensus: leu"
                     /tool="antismash"
                     /translation="EQSLARHARLPALNIQGRRISYAQLQGQALAIQAQLLPLLSSDRP
                     LVAVCLPKSPALYASLLAVLGCSAVYLPLDPATPSERLAFILKNAGAALLIHDGRIREW
                     DRSIPDLDLSQLPEPVAAPSTRLLRRLPGADEPCVAIYTSGTTGQPKGVLLSQRNLSHF
                     QVWYSGHVQLTAQSRVLQFSTINFDASLLDILPTWVAGAELVVPDEEQRRDPARLEALI
                     REQEVSHAFLPPALLSLLKLEGTGLEHLVSGGDVCEPDVIERLAGRCRFHNIYGPTETT
                     VLATTRVFANGDNPRNLGTPISNARVFLLDEALQPVPERSVGELYIGGPGVGLGYLNNP
                     ELSRERFISLELPDGECLRLYRSGDLGQWTADGIEICGRRDNQVKIR"
     PFAM_domain     11569..12729
                     /aSDomain="AMP-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00501.30"
                     /description="AMP-binding enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg50_8_0016"
                     /evalue="9.20E-76"
                     /label="ctg50_8"
                     /locus_tag="ctg50_8"
                     /protein_end="576"
                     /protein_start="189"
                     /score="255.2"
                     /tool="antismash"
                     /translation="EQSLARHARLPALNIQGRRISYAQLQGQALAIQAQLLPLLSSDRP
                     LVAVCLPKSPALYASLLAVLGCSAVYLPLDPATPSERLAFILKNAGAALLIHDGRIREW
                     DRSIPDLDLSQLPEPVAAPSTRLLRRLPGADEPCVAIYTSGTTGQPKGVLLSQRNLSHF
                     QVWYSGHVQLTAQSRVLQFSTINFDASLLDILPTWVAGAELVVPDEEQRRDPARLEALI
                     REQEVSHAFLPPALLSLLKLEGTGLEHLVSGGDVCEPDVIERLAGRCRFHNIYGPTETT
                     VLATTRVFANGDNPRNLGTPISNARVFLLDEALQPVPERSVGELYIGGPGVGLGYLNNP
                     ELSRERFISLELPDGECLRLYRSGDLGQWTADGIEICGRRDNQVKIR"
     aSModule        11569..14073
                     /complete
                     /domains="nrpspksdomains_ctg50_8_AMP-binding.1"
                     /domains="nrpspksdomains_ctg50_8_PP-binding.1"
                     /domains="nrpspksdomains_ctg50_8_TD.1"
                     /final_module
                     /locus_tags="ctg50_8"
                     /monomer_pairings="leu -> leu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     aSDomain        11629..12801
                     /aSDomain="TIGR01733"
                     /aSTool="tigrfam"
                     /description="AA-adenyl-dom: amino acid adenylation domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg50_8_0003"
                     /evalue="1.00E-110"
                     /identifier="TIGR01733"
                     /label="ctg50_8"
                     /locus_tag="ctg50_8"
                     /protein_end="600"
                     /protein_start="209"
                     /score="368.3"
                     /tool="antismash"
                     /translation="SYAQLQGQALAIQAQLLPLLSSDRPLVAVCLPKSPALYASLLAVL
                     GCSAVYLPLDPATPSERLAFILKNAGAALLIHDGRIREWDRSIPDLDLSQLPEPVAAPS
                     TRLLRRLPGADEPCVAIYTSGTTGQPKGVLLSQRNLSHFQVWYSGHVQLTAQSRVLQFS
                     TINFDASLLDILPTWVAGAELVVPDEEQRRDPARLEALIREQEVSHAFLPPALLSLLKL
                     EGTGLEHLVSGGDVCEPDVIERLAGRCRFHNIYGPTETTVLATTRVFANGDNPRNLGTP
                     ISNARVFLLDEALQPVPERSVGELYIGGPGVGLGYLNNPELSRERFISLELPDGECLRL
                     YRSGDLGQWTADGIEICGRRDNQVKIRGFRVEPEEIEHCLRASRLFAQVVV"
     CDS_motif       11986..12036
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg50_8_0001"
                     /evalue="6.00E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg50_8"
                     /protein_end="345"
                     /protein_start="328"
                     /score="21.9"
                     /tool="antismash"
                     /translation="AIYTSGTTGQPKGVLLS"
     CDS_motif       12529..12609
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg50_8_0002"
                     /evalue="5.00E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg50_8"
                     /protein_end="536"
                     /protein_start="509"
                     /score="44.4"
                     /tool="antismash"
                     /translation="SVGELYIGGPGVGLGYLNNPELSRERF"
     CDS_motif       12697..12759
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg50_8_0003"
                     /evalue="1.30E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg50_8"
                     /protein_end="586"
                     /protein_start="565"
                     /score="33.3"
                     /tool="antismash"
                     /translation="CGRRDNQVKIRGFRVEPEEIE"
     aSDomain        13045..13245
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg50_8_PP-binding.1"
                     /evalue="1.80E-16"
                     /label="ctg50_8_PP-binding.1"
                     /locus_tag="ctg50_8"
                     /protein_end="748"
                     /protein_start="681"
                     /score="52.3"
                     /tool="antismash"
                     /translation="ERLLTLWSELLELPAEDISTDDSFFNLGGHSILLSRLLLALRDGF
                     GRGISINRFIETPTLQRLSALL"
     PFAM_domain     13045..13245
                     /aSDomain="PP-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00550.27"
                     /description="Phosphopantetheine attachment site"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg50_8_0017"
                     /evalue="1.80E-14"
                     /label="ctg50_8"
                     /locus_tag="ctg50_8"
                     /protein_end="748"
                     /protein_start="681"
                     /score="53.9"
                     /tool="antismash"
                     /translation="ERLLTLWSELLELPAEDISTDDSFFNLGGHSILLSRLLLALRDGF
                     GRGISINRFIETPTLQRLSALL"
     aSDomain        13357..14073
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg50_8_TD.1"
                     /evalue="6.60E-55"
                     /label="ctg50_8_TD.1"
                     /locus_tag="ctg50_8"
                     /protein_end="1024"
                     /protein_start="785"
                     /score="177.8"
                     /tool="antismash"
                     /translation="VIVTGANSFLGVHIVEALLAWGASEVACLVRRGEGVGAAERFARA
                     LSDNRIGALDWRRVRVLEADLRMPRFGLSDTEYEDLDRRFGSLVHNAAQVNHVLDYPAL
                     AADNVEPLFECLRLCEGRSKKIFNFVSTLSACSARDAQGRVLEQPPAATPPLYIRNGYN
                     LSKWVGERILQRAREQGVRVNLFRPGNITFDSRSGVSQPHKNRLMLMLKGSLQLGQVPA
                     LDLEFDLMPVDFLARFI"
     aSDomain        13357..14424
                     /aSDomain="TIGR01746"
                     /aSTool="tigrfam"
                     /description="Thioester-redct: thioester reductase domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg50_8_0004"
                     /evalue="1.00E-94"
                     /identifier="TIGR01746"
                     /label="ctg50_8"
                     /locus_tag="ctg50_8"
                     /protein_end="1141"
                     /protein_start="785"
                     /score="315.8"
                     /tool="antismash"
                     /translation="VIVTGANSFLGVHIVEALLAWGASEVACLVRRGEGVGAAERFARA
                     LSDNRIGALDWRRVRVLEADLRMPRFGLSDTEYEDLDRRFGSLVHNAAQVNHVLDYPAL
                     AADNVEPLFECLRLCEGRSKKIFNFVSTLSACSARDAQGRVLEQPPAATPPLYIRNGYN
                     LSKWVGERILQRAREQGVRVNLFRPGNITFDSRSGVSQPHKNRLMLMLKGSLQLGQVPA
                     LDLEFDLMPVDFLARFIAFHASRHHPAQAVFNLHNPQPLRWAGYVEAFRKDGRAFELVS
                     VAQWQHALQRVDRDNALFEVLGFYLDGFEEDIGDTTLIDHANAREGVQRMGEDYPEKSP
                     ALLERGRQYLREIRFI"
     PFAM_domain     13363..14073
                     /aSDomain="NAD_binding_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07993.14"
                     /description="Male sterility protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg50_8_0018"
                     /evalue="5.50E-48"
                     /label="ctg50_8"
                     /locus_tag="ctg50_8"
                     /protein_end="1024"
                     /protein_start="787"
                     /score="163.5"
                     /tool="antismash"
                     /translation="VTGANSFLGVHIVEALLAWGASEVACLVRRGEGVGAAERFARALS
                     DNRIGALDWRRVRVLEADLRMPRFGLSDTEYEDLDRRFGSLVHNAAQVNHVLDYPALAA
                     DNVEPLFECLRLCEGRSKKIFNFVSTLSACSARDAQGRVLEQPPAATPPLYIRNGYNLS
                     KWVGERILQRAREQGVRVNLFRPGNITFDSRSGVSQPHKNRLMLMLKGSLQLGQVPALD
                     LEFDLMPVDFLARFI"
     CDS             14452..14919
                     /NRPS_PKS="Domain: Polyketide_cyc2 (17-152). E-value:
                     8.8e-18. Score: 56.9. Matches aSDomain:
                     nrpspksdomains_ctg50_9_Polyketide_cyc2.1"
                     /NRPS_PKS="type: other"
                     /locus_tag="ctg50_9"
                     /transl_table=11
                     /translation="MQVLKPDTLIRNPQGCLVVSQVDIAAEAANVWNIVGNFAGFAVFI
                     PALSHIEMTGSGVRSIRKKFFKDNNFVIEQLNSRDDKAMSMTWSLIHTSLNIGNLWAAM
                     EVKSLGEGHSRAVWTIQAEPYEGGPEALPGFQAFLQTFADDAMNNVRNLLS"
     aSDomain        14503..14907
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg50_9_Polyketide_cyc2.1"
                     /domain_subtype="Polyketide_cyc2"
                     /evalue="8.80E-18"
                     /label="ctg50_9_Polyketide_cyc2.1"
                     /locus_tag="ctg50_9"
                     /protein_end="152"
                     /protein_start="17"
                     /score="56.9"
                     /tool="antismash"
                     /translation="VVSQVDIAAEAANVWNIVGNFAGFAVFIPALSHIEMTGSGVRSIR
                     KKFFKDNNFVIEQLNSRDDKAMSMTWSLIHTSLNIGNLWAAMEVKSLGEGHSRAVWTIQ
                     AEPYEGGPEALPGFQAFLQTFADDAMNNVRN"
     PFAM_domain     14503..14910
                     /aSDomain="Polyketide_cyc2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10604.11"
                     /description="Polyketide cyclase / dehydrase and lipid
                     transport"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg50_9_0019"
                     /evalue="4.90E-12"
                     /label="ctg50_9"
                     /locus_tag="ctg50_9"
                     /protein_end="153"
                     /protein_start="17"
                     /score="46.4"
                     /tool="antismash"
                     /translation="VVSQVDIAAEAANVWNIVGNFAGFAVFIPALSHIEMTGSGVRSIR
                     KKFFKDNNFVIEQLNSRDDKAMSMTWSLIHTSLNIGNLWAAMEVKSLGEGHSRAVWTIQ
                     AEPYEGGPEALPGFQAFLQTFADDAMNNVRNL"
ORIGIN
        1 ccacgccggc ggtcactgcc gtaaccgata ccgtcgatac cagcaccgtg accctgaccg
       61 ccacgccaaa cgtggccgaa ggcggcgtag tgacctacac cgctaccgtc agcgctccag
      121 tgaccttggc tccactggta atcaccctgg ccaacaacca gaccatcacc atcgcggtcg
      181 gccagaccgt gggcacggtc aacttcaccg caccgaacaa cgtctacacc gccaacccga
      241 cgctgaccaa cagcatcacc ggggtcagcg gcggcaacta cgagaagctc gacgccaccg
      301 gcaccaccag caccacgatc accgatggcc cgatcgacac caccaacgtc accctgaccg
      361 ccaccgcctc ggtcgccgag ggtggccagt acagctatac cgcgaccttg accaacctgg
      421 cggcatcgcc ggtcaccgtg accctgtcca acggactgac catcgtcatt ccgaaggacg
      481 cactgtccgc cacgatcctc gtcaatgccc cgaccgatac gccgtacatc gatgccggca
      541 gcaccagcgc gaagatcacc ggggccagcg gcggcggctt cgagaacctg acgttcggca
      601 ccaacaccgt gatcacccag atcaccgaca ccgtcacgcc gaccacggtg agcatcaccg
      661 gcaccacgtc ggtggccgaa ggcggcaccg cgacctacac gatcaacctg agcaacccgt
      721 cgcagtccgc ggtcacggtg aaactgagct actcgggaac cgccgccaac ggcagcgact
      781 acaccgggac caccaccgtg accatcccgg ccggcgccag caaggtcgac ttcagcatcc
      841 cgaccatcaa ggacgccgtc accgaaggca ccgaacagtt caccgtcaag gtcgactcgg
      901 ccagcggcgg caacttcgag agcctggtgg tcagcggtac cgccggcagc gtgacgacgc
      961 agatcttcga accggcaccg atcctcgacc tggacggcaa caattccagc ggcaagaccg
     1021 gcgcggacta ccaggtgacc ttcaccgaag gccagccagg caccggtgtg tcgatcggcg
     1081 atgtcgacct gagcatcacc gatatcgaca gcaccaacct gaccggcgcc accgtcaccc
     1141 tgaccaaccg cctggcgggc gacgcgctga acctcggcaa cagcgtcaac ggcatcagca
     1201 tcaacgccgt caacaccaac gacaaagtgg tgctgaccct gagcggcaac gcgagcatcg
     1261 ccgactacat ccagcgcctg aagaacatta ccttcatcaa caccagcgac gatccgagca
     1321 gcacgccacg gaccatcacc gtgacggtca ccgacggggt gaacacctcc aacgtcgcca
     1381 ccaccacggt caacgtggtg ccggtgaacg atgcgccaac ggctgccggc ggcgagatca
     1441 ccggcaccga ggacaccgat ctggccctga cctggaccag cctcggcgtc agcgacctgg
     1501 acaacgccgc cagcgcgctg ggcatcacca tcacccagct gccggtcaat ggcaccctgc
     1561 agtacaagga cggtgcgacc tggaagaccc tcaccgcggc cgacgccggc aaggtcttca
     1621 gcaaggccga tatcgatgcg ggcaacctca agttcgtgcc tctggccaac cagtcgggca
     1681 tcaccgccaa cggcggcacc ggcgtgggca accagcaggc cgactacgcg cagctcaagt
     1741 acaagccgta tgacggccag gcgctgggca acgaagccac gctgaagatc gacatcaccc
     1801 cggtcgccga caaaccgacc ctgaccatcg gcagcaatgc cgtggcctcg atcggcctga
     1861 ccaaagagat ctacaccggt ctctcgggcc tgggcaccaa cggcaacggc gccgatgccg
     1921 cgaccctgaa gtcggtgatc gatgcggcgg cgggcaaggc gcaatccacc gccatcgcca
     1981 ccaacgtgac ggcggcggat gtcaccgcgg gcatcgcctc gaagacctcg ggcctgatgt
     2041 acatggaagc cggcagcacc tacaagttca ccggcgtcgg cgatgacagc ctggcggtgg
     2101 tcgtgggcgg ccgggacgtg gccagcacca cctggggcgc cggtggccag ctcaacggca
     2161 ccttcacccc ggccaagagc ggctactaca ccgtcgagat ctaccactac aaccaggccg
     2221 gtccgggcag ctacgacgtc aacgtgtcgg tcaatggcgc cgcggccatc gacgtcagcc
     2281 aggtcggcac cgcgctgtac ccgaccgccg ccgcgctggc cgcggccggc gtgaccgtcg
     2341 ccgacttcca cggcagcaac ggcaagggct actacgacgg ctacaaactc aacgagggcg
     2401 gcgagaacgg caccgtcaag ctggtcggca tcagcgcggc gctgaccgat accgacggtt
     2461 cggaaaccct gagcgtcaag ctcggcggca ttccggtcgg ctcggtgatc agcgacaacg
     2521 ccgggcacag cgtcaccgtg ggcgctaccg cggtggacgt cagcggctgg aacctgaaca
     2581 acctcagcat caagccgccg gcgtactaca gcggtacctt caacgtcgcg gtcagcgcca
     2641 cctcgaccga gaccatcaat ggcagctcgg tctcgacgcc ggacaccatc aaggtcaccg
     2701 tctacggcga tacctatgcc gtggcgacca acgcaacggc cgaaagcgac acctggaccg
     2761 gcaccgacgg caacgacatc atcgccgccg acatcaacgg cctgcatgtg gtcgccggac
     2821 agagctacaa cctggcgttc atcgtcgaca cctccggcag tatgaagtcg gacggcgtgg
     2881 acgcggcgca gaaggccctg cagtcggtgt tcacgaccct gtccaacagc gtccagggcg
     2941 cgtcctcggg cacggtgaac attctcctgg tggacttcgc cacccaggtc aaatccaccg
     3001 tgtcggtcaa cctgggcgac agcggcgccc tgcagaccct gaagaacgcc ctgacgacga
     3061 tgtcgtccgg cggcggcacc aactacgagg acgccttcaa gaccacggcc aactggttcc
     3121 agaacctggt cagcgccggc aataccggga agaaccagac gttcttcatc accgacggcg
     3181 agccgaccta ctaccagagc ggcgagcgcg acaacccgac gctggtcaag ggcagcggtt
     3241 ccaaggccga gatcaccatg gacaactacc tgacgtcgat cggctacaag ctcggccagg
     3301 tggtcaacgt caacgtcgac agcaacaaca ggctgacgat cgacagcagc ggcaacctga
     3361 acctgtacaa gaacggcaac tactactcgt cgctgagcgg caccctgcac gcccagggcg
     3421 acggcaccta cgagctgtcg agcctggccg gccagggcaa ctacgccgac tccgacacca
     3481 tcagcaactc gaagagcgcg ttcgccgtgc tcaaggcgct gtcaccgacc gtggaggcca
     3541 tcggcatcaa cagcggcgtc gacgtcaacg acctgaaacc gtacgactcc gacggagtgc
     3601 cgcagaccaa catcgacccg agcaacctgg ccaacgccat cctcggccac accgaagcga
     3661 ccctgccggg caacgacacg gtcaatgcca acgacggcaa cgacatcgtg ttcggtgacc
     3721 tgatcatgtt ctcgacggta tcgggcaacg gggtggaagc cctgcagagc tacgtcgcga
     3781 aacagaccgg gctggacgcc agcgcggtcg acagcaagac catgcaccag tacatcaccg
     3841 agcatgtcag cgagttcgac gtctcgcgca ccagcgatgg cgacgacaag ctgtatggcg
     3901 gccagggcaa cgacatcctc ttcggccagg gcggcaacga cctgctcgac ggcggtgccg
     3961 gcaacgacat gctgctcggt ggcagcggca atgacaccct gctcggcggt gagggcaacg
     4021 acctgctgtt cggcggcaag ggcaacgaca ccctgaccgg cggcagtggc gccgacacct
     4081 tcatctggaa ggccggcgac accggcaacg acatcatcaa ggacttcaag gcggccgaag
     4141 gcgaccgtct cgacctgagc gacctgctcc agggcgagaa ggccagcacc atcgacaact
     4201 acctgaagat caccacggcg aatggcgatt cgaccctgca ggtcagcagc gaaggcaagc
     4261 tcaacgccgc gggcggtatc gccaacgccg acgtgacgat caaactggag ggggtgaact
     4321 ggtccaacac cacgatcaat tcgttgatca gcggtgccga cccgaccatc aagatcgacc
     4381 acaacaacag ctgatgacgg gaatcgcgcc agcctcttcg ggggctggtg cgggccgtgg
     4441 tctttgcctg gccgtcagcg gcggcgcata ctcgtgcgcc gccggctcgc agcggctggt
     4501 cgaggactgc gggcgccccg acaagcccgt gcccaaaagt acgacaagca gtccacagca
     4561 acgtggcaac ggcgtagcca tttccgatac agggcctatt ctctgaaggc gactatggat
     4621 tcacattctc gaggaaaccc catgttctac gtgcaacgcg atgccgaggg ccaactgctg
     4681 cgggtcgagg cggccgcctt tgccgaagcc acggaaattc tcccggccga tcatgccgag
     4741 gtgctggagt ggttcgccga cgatgtcgtg gaaaacagcc tcaagcagct caagcagagc
     4801 gacctggaca tgatccgggt actggaggac ctgatcgaag tcctgaccac caaaggcgtg
     4861 atcagcatca ccgacctgcc ccccggcgcc caggccaaat tgctcaaccg caataccgca
     4921 cgcgccgcgc tcggtggcct gaacaacctg atcgacgacg aagaggtcgg cggtctgatc
     4981 tgaaccctgt cggcctcgcc aacgaggccg ggttcacgcc cagggtgccg gctcgcccac
     5041 cagccggccc tgcacgccct ggatctgcat ctcttgcagc acctgcaact ccccttcggt
     5101 ttccacgcgc tcggcgatca gcggcaggtc gatgctgtgc gccgcgcgct gcaccgcctc
     5161 gatgaacagg cgtttgtgct gctcctgatc gatggcacgg atgtagctgc cgtcgatctt
     5221 caggtaggcc agccccaggt gggcgaggtt gccgatcatg ctgaagcgtc ccccgaagtg
     5281 ctgcaggctc agactgaaac cgaggacgcg caggcgtcgg gtcagttgct ccagcacggc
     5341 ctgttccggc aattgttcct cggcgatctc cagggtcagg cgcggaccga gcacggcatg
     5401 ctgggccagc agctcgaaca cgcgctgctg gctcgccggg tcgaccaccg tggtcgccga
     5461 caggttcagc gccagcgcct ggtcgtgccc gtgcatctgc ttgaggacct tctccagcat
     5521 caccaggtcg agccgactcg accagccgaa gcgctccagc gccggcagga agcggcccgc
     5581 ggcgatggtc tcgccgttgt cgtcgaccaa ccgcgacaga accttgtagt gcagtacgcg
     5641 gtccagctga ttgcagtcca ccaccggctg gaagaacaac cggaagcggc cctggttcag
     5701 cgcctcgtcc agcaggttgt gccactgccg gtgggtatcg ctggcctggg acgcagaacc
     5761 ctgctccagg catacccagg acggctccgg ctggctctgc gcccgcgcca gcgcctcgtc
     5821 ggccagttgc agcagggctt tcggctcgtc accggggctg aaaggcgcca ggccgatgca
     5881 gaccgacggg gtgacatcgg aaataccgcg caggccgact tccagggcct gggccagggc
     5941 gatggcatcg tcatgggtca tgcccggcgc cagcacggcg aactcgccac cgcgactgcg
     6001 ggtgatcagg ttgttggttt ccgggtaggc ggaacagatg cgctgcagtt gctgacccac
     6061 cgcccgcagc aactggtcgg tgcgctgacc gccgagacgc tggttcagac cggccaggtc
     6121 ctgcacccgc aacagcagca ggtagccttc gcgggcctcc tccagattgc tcacccgggc
     6181 attcagctgc atctcgaaat agcgccggtt ggccaggccc gtgaggctgt cctgatagga
     6241 ctcgacccgc agcttctcgc tgcgctcggc ctgctcctga tacagcgcct tgagcttctc
     6301 gaccatctgg ttcatggcct gcaccacgcg gcgcagctcc ggggtacgcg gcaggtccgg
     6361 caggctgagg aactcgcgac gggcaatggc gtgggactgc tcgaccatgt agtccagcgg
     6421 cttcagttgc cgccgcagca acagggcgcc ggccaccgcg ctgaggccac cgcacagcag
     6481 cagccagcca aggctgccga gggcgctctg ccacagcttg gcgagggcga acatcgggtg
     6541 actgaccacc tcgacccgcg ccgcctgctg ccaaccgcgc atgacgatgg cgtcaccacc
     6601 ggccgcctcc aggccgatca gctggatgaa ccattgcggc acgccacccg gatcaggatc
     6661 ggcgtgacgc tcgaccagca aggcgctgga accgagatcg acgacacgga tgctggcgta
     6721 gtagccgctg tcgaagatcg aactgaccaa cagctcgacc atcgccgggt cgtccaggtt
     6781 cggcgtcagc gacagcgcca gcgccgtggc ggcatcctgg gcgtgggagc gcagctggtt
     6841 gacgtactgg ctgcgcgagc tttccaggct gaccatgaaa ctgccactga aagcgaccac
     6901 cagaaacagg cagatggcga gcaacaattg tttgaacagt gacatcggag ctcctcagta
     6961 aaccggctcg gcagggaatc cttccgcctg cattttcttt aacagatctt gccagcgcga
     7021 caagcgcttg gtgtcgccca ctttcttgtt gcccgccgcg ccggtcagcc acaggccctc
     7081 gccattgaag gcgtagaccg gcagcagatc ggtgcgttgg ctggccggct tgatcgcgtc
     7141 gatcaggctg tcgaggacca ggggcatggc gtcaggactt gaatagtagg tcaggaccat
     7201 gtgcgcgcgg ttctggcgca gtgccttgac gtaggtgatg cgcaatttgt cggcgggaat
     7261 gccgagacga cgcaggctga agtacttggc gatggcgtag tcctcgcaat ccccggcacc
     7321 tttgatcagc gactggatcg gtgtggccca gtaatcgact tcgtgccaca ggtcaatgtc
     7381 ctcttcatag cgcaactggc ggttgaagaa ctgattgacc acctgcagac gctccgcctc
     7441 gccgagctgc ttctgcgtcg ccagcaattg ctgccaggca tcgatgcgct gctggccagc
     7501 acccagcggg ccatacaggg ccgcggcctt gcggctgatc tgggagaaat cccagtcggc
     7561 acgcaacccg cccagcagcg ccaggccaag caacaaggcc agcgacgccc ggcgcaggag
     7621 cagatgaaga gtccaacgta tcgccaaggc gaactgtccg cgaaatcact gggaacgccg
     7681 atggtgccgc cagccctgtg aaaaaacaat ggcacaggac aatcactgcg atatcaccgc
     7741 gccctgacgc ccgacaatcg gttgacgcgc ccttcatcac gacgctttcc ttcgttctaa
     7801 agttcattca cgattagcac cgcattcagc ggcaggcgcc tcacggcgta gggcgaaacg
     7861 gttccgccac cgatggcccg cccggtttga caaggatcga ctccctcact agcttgattg
     7921 gatccaatcg agcaccgaat tgcaggacaa catcagcgtg gccggaaaaa ccaaactcct
     7981 gagcaacatc ctgggtgacg aacaggtgcc cgcgcacctg gcgcgaagcg tgatcgaaga
     8041 acgtttgcgc agtgccattc tggatggccg cctggcgccg ggcatggccc tgcgacagca
     8101 ggagctggca acgctgttcg gggtcagtcg catgccggtt cgcgaagcgt tgcgccaact
     8161 ggaggcgcaa tccctgctcg aagtggtgcc gcacaagggc gcggtggtgg cgccgctgat
     8221 cggcgaagac gcggtcgata cctacgagct gcgggtcatg ctggaaaccg aggcactgcg
     8281 ccagtccatt ccgctgctgg gccccgacga catcgccctg gctcgcagct atatccacca
     8341 gctggaaaac gaaacccgcc attccgagat cggccgactg aaccggctgt tccacatgac
     8401 cctgtacagc aaggcgaaca acaccaagct gctgcgcctg atcgacaacg aactgctgca
     8461 ggaagagcgc ttcctgcgct tccacctgtc ctccatgggc ctgggcaagc tgacccagga
     8521 cgatcacaac ggcctcaccg acgccgccaa cgacaaggac atcgaacagg ccgtggtcat
     8581 cctgcaccgc cacctgaaca acgcgatgag gaccatccgc gactacctga gccgcaagga
     8641 caagtaagtc tcgtcgcccg ctatcgagcc tgccgcactg gcaggtctgc ctctctcccg
     8701 cccttcgcag cctacacggc catcgtcgag ccatgacagc catggcgttt tctgcacact
     8761 ctaacggcag caagtgaccg gttggtcggc tgcggcaacg cccctcactt gccagtccgc
     8821 caccagtaga aggagccatg caccgggcga gggccgccag cgatcaaccg cccccgatat
     8881 ttcagaacga tcgacttgcc cattggaaag tgcccggggt gaggcattca ctcatgaacc
     8941 gattactttg gttgcaaata gccgaagcgg gcaacttcat tcaaataaaa caacttcaac
     9001 ttgttttatc aactaaacac atgccagaga aaagacccac acaaatatat ccacaaaacc
     9061 acttgcggat aactttgaag ttgccttagc ttcaaaacgc cggcagccat ttcgccaaca
     9121 gcgggacagc cagcactgta aacacttctc caagagcctc gcggcagagc attcgccggt
     9181 tatttctcga aggccggcac tcgcccgaaa taaagttacg gcaactaacg cctgttgtac
     9241 cggcatgaac ttctgcaacc actcgatcag caaaggaact tgcaatgaat cctctccaag
     9301 cactgttgca tgaaaagaaa agcgaactgg cgaagcatcc aatctttgcc gaaatagatt
     9361 cgcttccggt attgcgccgc ttcatggaaa cccatgtcta cgctgtctgg gatttcatgt
     9421 ccctgaccaa gcgcctgcag caggaactga cctgtatcca gctaccctgg ctaccgccga
     9481 aggacccgaa ggccgctcgc ctgatcaacg agatcgtgct cggcgaggag tcggacgacc
     9541 gcctcgacca cgatcactac agccacttcg agctgtatct ggatgccatg cgcgaggtcg
     9601 gcgcctgtac ggccagtgtc gaacgtttcg tcgccctgca acgcgacggc ctgcaccatc
     9661 gcgccgccct caccagcgcc ggggccagcg aggcggcgcg gcatttcgtc gaacagaccc
     9721 tggacatcgc gctcaatgcc ccggcccatg ccgtcgcagc ggccttcctg cacggtcgcg
     9781 agagcgtcat cccaaccatg ttccagcgca tcctcgacga ctggggcatc accggcagcc
     9841 aggcaccgac ctttcgctac tacctgcagc ggcatatcga agtggactcc gaagaccatg
     9901 gcccggcggc cggacaactg ctggcgcgtc tggtcggcga cgacccacaa cgcgaacgcg
     9961 aggtgtacga agccgccatc gccgcggtgg agagccgcct ggcgttctgg gatcgcctgc
    10021 gggtgtccat gcaccaggaa attgccgagg tcaacgtatg aacgatctcg actaccaatc
    10081 cttcgccgag gcctgggagg gtcgggcaac catccgcacc cggccaagac gcctggtgga
    10141 agacgaccag cggctgatct tcccgctgag tcgccagtcg ctggtgctca ccgccacgtt
    10201 ccagcgcgaa tgcccgcatc tgtgcgattt cgtcctggtc cagagcctct acaagttcat
    10261 caatgacgtg gtgatcttcg agaccgagat cgttgaccgc accgcccgcg cgatcgccaa
    10321 ggaccgcttc gccgtgcgct ttcctttcgc ctgccgctac gacgccatga ccgtggtggt
    10381 cgacgaggac tatcacgccc tggtggccat ggatttcatg cagcagaccg tcgcgctcac
    10441 aggcgttcaa ccgctggcgc tgccacggga aatcgagctt agccgggcca ttcccgccgc
    10501 cctgagcctg gccccggagc acctgcgtga cgcggtggag ctgatctgcg tgggcatcgc
    10561 cgagaacacc ctgaccaacg atgtcgccgc gttcgcccgc gatgacagcg tgaagggttc
    10621 gatcaaggga ctgatggccg accacctgct cgacgaaggg cgtcactcga ccttctgggc
    10681 acggctgacc cgcatctact ggagccaggc atccgcccag gaccggcagt gcattgccgg
    10741 gatcctgccg gtgttcctgc ggcactacct gaccagcgag attcagcaag ccttcgacct
    10801 gcaactgatc gacgccctgg acgtgccacc cgcggtcacg gcggcgctgc gcgcggaggc
    10861 gagcgggatg gactggccga tcggtccccg ccaccccttg ctgggcaaca tcctgcgctt
    10921 cttccgtaac agctcgttgc tcgacacgcc ctgcgtacaa gaggcgctga tcgactacct
    10981 gcccttatcg aggaccgcgc catgagacgc ctggatatcc tgctggcggg aaacagcccg
    11041 gcgctcggcc agttgttcga agaactggag caacatggcc atacgctgca tcacgcgaag
    11101 gcaactcaag aactgactgc acatccctcg acccgtccgg acctggtgat cgaggacggc
    11161 agtgtcgatc tgccggacct cggtgccggt atcgtcctca gcctgcgggt gggaagcggg
    11221 gacacgcttg tcgccgaact gcccgaagtg gagttgctgt actgggccgg cagcgcacgg
    11281 gcgcaaaggc tgatcgaccg acagccactg gagaaggagg catcaggcaa cggccaggaa
    11341 ctgcgtatga ccgcattaag tgctctgcgg gaacgcgtgg ccttgcatgt cagtcgtttc
    11401 tcacgcaatc ccgagcattt ccgcgagcgc gagaccatcg ggccaatgtg tcaggcccat
    11461 gaacattccc tgccctggct ggagcgactg gcctggttgc atcgcttcaa ccgcgatgcg
    11521 caagacggct tgctgcaggc cagcgaatca gcgctgatcg agcgcctgga gcagagcctg
    11581 gcgcggcacg cgcgactacc ggcgctgaat atccagggac gccggatcag ctacgcgcaa
    11641 ctgcaagggc aggccttggc gattcaggcg cagttgctac ccttgctgtc ctcggacagg
    11701 ccattggtgg ccgtgtgcct gccgaagtcc ccggcgctct atgcgagcct gctggcggta
    11761 ctgggctgca gcgcggtgta cctgccactg gatcccgcca ctccgtccga acgcctggcg
    11821 ttcattctga aaaacgccgg ggcggcgctg ttgattcatg acggacggat ccgcgaatgg
    11881 gacaggtcga ttcccgatct ggacctgagt cagcttcccg aacccgtcgc ggcgccgtcg
    11941 acgaggctgc tacgccgact tcccggcgcg gatgagccct gcgtcgcgat ctatacctcg
    12001 ggcaccaccg gccagcccaa gggcgtgttg ctcagccagc gcaacctcag tcatttccag
    12061 gtctggtaca gcggccatgt gcaactgact gcgcaaagcc gcgtactgca gttttccacg
    12121 atcaacttcg atgcctcgct actggatatc ctgccgacct gggttgccgg ggcggaactg
    12181 gtggttccgg atgaggagca acgccgcgat ccggcgcgcc tggaagccct gatccgcgaa
    12241 caggaagtca gccatgcctt tctgccgcca gccctgctca gcctgctgaa gctggagggc
    12301 actggcctcg aacacctggt cagcggtggt gacgtctgcg aaccggacgt gatcgagcgc
    12361 ctggccggcc gctgtcgctt ccacaatatc tatgggccga ccgaaaccac cgtactggct
    12421 accacgcggg tattcgccaa cggagacaac ccacgcaacc ttggcacacc catcagcaat
    12481 gcccgcgttt ttctcctcga cgaggcgctg caaccggtgc cggaacgcag tgtcggcgag
    12541 ctgtatatcg gcggtcctgg tgtcggcctg ggttatctga acaatcccga gctgagccgc
    12601 gagcgcttca tctcgctgga actgccggat ggcgagtgcc tgcgcctgta tcgcagcggc
    12661 gacctgggcc aatggaccgc cgacggcatc gagatctgtg gacggcgcga caatcaggtg
    12721 aagatccgcg gcttccgcgt cgaaccggaa gagatcgagc actgtttgcg tgccagccgt
    12781 ttgttcgccc aggtcgtcgt ggtgatcgac gaacaacgcc gcgtgctgag ctttctcgcc
    12841 caaccgcgcc agaccgcagc cctcgagcgg ctccgcgccc atgccgagca gaacctgccc
    12901 gactacatgc gccccctgct ctatcaggag ctgccgcaga tgccctgcac ggccaacggc
    12961 aaggtcgacc ggcgcgcctt gctcagcctg ccggttaccc ttgccggcgc gcgacaacga
    13021 ctggcgccgg ccaatgccct ggaagaacgc ttgctgacgc tgtggagcga actgctggag
    13081 ttgcccgcgg aggatatttc caccgacgac agtttcttca atctgggtgg gcactcgatt
    13141 ctgctgtcgc gcctgctgct ggcactgcgc gacggcttcg gccgcggcat ttccatcaat
    13201 cgctttatcg agacgccgac cttgcagcgt ctgtccgccc tcctcagcgg tgagaccacc
    13261 acggtcgggg cgctgcatcc ccaggcattg agcgacgccg accgggcact ggaactgcgt
    13321 gtgctgccgc tggagcagct gggagatgtg cacagggtga tcgtcaccgg ggccaacagc
    13381 tttcttggtg tgcatatcgt cgaggcgctg ctggcttggg gggcgagcga agtggcttgc
    13441 ctggtgcggc gtggagaggg cgttggcgcc gccgagcgct ttgcccgggc actgagcgac
    13501 aaccgtatcg gcgctctgga ctggcgccgt gtccgggtcc tggaagccga tttgcgcatg
    13561 cccagattcg ggttgagcga caccgagtac gaagacctcg atcgtcgttt tggctcgctc
    13621 gtgcacaacg cggcgcaggt caatcacgta ctggattatc cggcgctggc cgcggacaac
    13681 gtagaaccgc tgttcgaatg cctgcgcctg tgcgaaggac gcagcaagaa gatcttcaac
    13741 ttcgtctcga cgctctccgc ctgcagcgcc agggatgcgc aaggccgggt gctcgaacaa
    13801 ccgccggcgg caaccccgcc gctctacatt cgcaacggct acaacctcag caagtgggtc
    13861 ggcgagcgca tcctgcaacg ggcacgggaa cagggggtac gggtcaatct gttcagaccc
    13921 gggaacatca ccttcgacag ccgcagtggg gtctcacagc ctcacaagaa tcgtctgatg
    13981 ctgatgctca agggttcgct gcaattggga caggtgccag ccctggacct ggagttcgac
    14041 ctgatgccgg tggacttcct ggctcgcttc atcgcctttc acgccagccg acaccacccc
    14101 gcgcaagcgg tcttcaacct gcataaccca cagccattgc gctgggcggg gtatgtcgag
    14161 gcgttccgca aggatggccg ggcattcgaa ctggtcagcg tcgcgcaatg gcagcacgcg
    14221 ctgcagcggg ttgatcgcga taacgcactg ttcgaggtgc tcggctttta cctcgacggc
    14281 ttcgaggaag acatcggcga caccacactc atcgaccacg ccaatgcgcg ggaaggcgta
    14341 cagcgcatgg gcgaagacta tcccgagaaa agtccggcac tactggagcg cggccgccaa
    14401 tacctgcggg aaatccgttt catctgattc accacccaga ggaacaacat catgcaagta
    14461 ctgaaacccg ataccctgat ccgcaatccg caaggctgcc tggtcgtctc tcaggtcgac
    14521 atcgccgcgg aggccgccaa cgtctggaac atcgtcggca acttcgccgg cttcgcggtg
    14581 ttcatccctg cactcagcca tatcgagatg accggcagcg gtgttcgttc gattcgcaag
    14641 aagttcttca aggacaacaa ctttgtcatc gagcagttga actcccggga cgacaaggcg
    14701 atgagcatga cctggagcct gatccacacc agcctgaaca tcggcaatct gtgggcggcc
    14761 atggaagtga agagtctggg cgaaggccac agccgggcgg tctggaccat ccaggctgag
    14821 ccctatgaag gcggaccgga ggcgctaccc ggattccagg cgtttctgca gacgttcgcc
    14881 gatgacgcca tgaacaacgt gcgcaatctg ctgagctgaa ccccagaaag acaaaacccc
    14941 tgtctgcgat gcagacaggg gttctggaat tgaatcttga cgatgaccta ctctcacatg
    15001 gagaagctcc acactaccat cggcgatgcg tcgtttcact gctgagttcg ggatgggatc
    15061 aggtggttcc aacgctctat ggtcgtcaag aaattctgtg tgccggtccg tcgtcgagac
    15121 agatccagcg aaattcttgg tacttctact t
//
