LOCUS       c00072_NZ_BBIR..       14874 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_BBIR01000087.1 Pseudomonas japonica NBRC 103040 = DSM 22348
            strain NBRC 103040, whole genome shotgun sequence.
ACCESSION   NZ_BBIR01000087
VERSION     NZ_BBIR01000087
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 16:47:01
            Original ID  :: NZ_BBIR01000087.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14874
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14874
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1058:4874]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1059..4874
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..14874
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14874
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             complement(61..1062)
                     /gene_functions="other (smcogs) SMCOG1094:ferredoxin
                     (Score: 159.9; E-value: 1.3e-48)"
                     /gene_kind="other"
                     /locus_tag="ctg72_1"
                     /transl_table=11
                     /translation="MSFQMRIEPVGLSCPVSPEQSVLDAALADGLMLKHSCRTGTCGSC
                     KGRLLSGQVDHADSPLEVLSEAERAQGLALFCCARARSDLVIEAPEVTELRGISIQQMG
                     VRVAAIDKVSHDVAVLRLMLAPGSTFSYFPGQYVQVLLKDGSRRSYSMATAAAREQQLE
                     LHIRHMPGGVFSGHVFNALQPKAILRMEGPFGSFFLRQGEAPMVFLASGTGFAPIQALL
                     EQLREQGNRRPVYLYWGGRRREDLYRHEQLLAWEAELAWLRYTPVLSEPGESCDWQGAT
                     GFVHRQVMEDFHSLKGFEVYACGAPIVVESARREYVAQRGLAEVDFHADAFV"
     PFAM_domain     complement(124..441)
                     /aSDomain="NAD_binding_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00175.23"
                     /description="Oxidoreductase NAD-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg72_1_0003"
                     /evalue="1.60E-17"
                     /label="ctg72_1"
                     /locus_tag="ctg72_1"
                     /protein_end="313"
                     /protein_start="207"
                     /score="64.2"
                     /tool="antismash"
                     /translation="FLASGTGFAPIQALLEQLREQGNRRPVYLYWGGRRREDLYRHEQL
                     LAWEAELAWLRYTPVLSEPGESCDWQGATGFVHRQVMEDFHSLKGFEVYACGAPIVVES
                     AR"
     PFAM_domain     complement(472..747)
                     /aSDomain="FAD_binding_6"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00970.26"
                     /description="Oxidoreductase FAD-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg72_1_0002"
                     /evalue="2.60E-15"
                     /label="ctg72_1"
                     /locus_tag="ctg72_1"
                     /protein_end="197"
                     /protein_start="105"
                     /score="56.6"
                     /tool="antismash"
                     /translation="RVAAIDKVSHDVAVLRLMLAPGSTFSYFPGQYVQVLLKDGSRRSY
                     SMATAAAREQQLELHIRHMPGGVFSGHVFNALQPKAILRMEGPFGSF"
     PFAM_domain     complement(820..1044)
                     /aSDomain="Fer2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00111.29"
                     /description="2Fe-2S iron-sulfur cluster binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg72_1_0001"
                     /evalue="2.20E-12"
                     /label="ctg72_1"
                     /locus_tag="ctg72_1"
                     /protein_end="81"
                     /protein_start="6"
                     /score="46.9"
                     /tool="antismash"
                     /translation="IEPVGLSCPVSPEQSVLDAALADGLMLKHSCRTGTCGSCKGRLLS
                     GQVDHADSPLEVLSEAERAQGLALFCCARA"
     CDS             complement(1059..2075)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 189.2;
                     E-value: 2.3e-57)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg72_2"
                     /sec_met_domain="HMGL-like (E-value: 1.2e-77, bitscore:
                     251.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIYISDVTLRDGSHAVRHQYTLDNARDIARALDAAKVDSIEVA
                     HGDGLQGSSFNYGFGRHTDLEYIEAVADVVSHAKIATLLLPGIGTVHDLKAAYDAGARV
                     VRVATHCTEADVSKQHIEYARELGMDTVGFLMMSHMIPAEQLAAQGKLMESYGAQCIYM
                     ADSGGAMNMQDIRERMRAFKAVLDPATQTGMHAHHNLSLGVANSIAAVEEGCDRIDASL
                     AGMGAGAGNAPLEVFIAAAERLGWNHGTDLYTLMDAADDIVRPLQDRPVRVDRESLALG
                     YAGVYSSFLRHAEIAAKRYGLKTVDILVELGKRRMVGGQEDMIVDVALDLLAARSAS"
     aSDomain        complement(1074..2072)
                     /aSDomain="TIGR03217"
                     /aSTool="tigrfam"
                     /description="4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate
                     aldolase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg72_2_0001"
                     /evalue="1.50E-179"
                     /identifier="TIGR03217"
                     /label="ctg72_2"
                     /locus_tag="ctg72_2"
                     /protein_end="334"
                     /protein_start="1"
                     /score="594.3"
                     /tool="antismash"
                     /translation="KKIYISDVTLRDGSHAVRHQYTLDNARDIARALDAAKVDSIEVAH
                     GDGLQGSSFNYGFGRHTDLEYIEAVADVVSHAKIATLLLPGIGTVHDLKAAYDAGARVV
                     RVATHCTEADVSKQHIEYARELGMDTVGFLMMSHMIPAEQLAAQGKLMESYGAQCIYMA
                     DSGGAMNMQDIRERMRAFKAVLDPATQTGMHAHHNLSLGVANSIAAVEEGCDRIDASLA
                     GMGAGAGNAPLEVFIAAAERLGWNHGTDLYTLMDAADDIVRPLQDRPVRVDRESLALGY
                     AGVYSSFLRHAEIAAKRYGLKTVDILVELGKRRMVGGQEDMIVDVALDLLAA"
     PFAM_domain     complement(1083..1262)
                     /aSDomain="DmpG_comm"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07836.13"
                     /description="DmpG-like communication domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg72_2_0005"
                     /evalue="1.20E-30"
                     /label="ctg72_2"
                     /locus_tag="ctg72_2"
                     /protein_end="331"
                     /protein_start="271"
                     /score="104.9"
                     /tool="antismash"
                     /translation="RVDRESLALGYAGVYSSFLRHAEIAAKRYGLKTVDILVELGKRRM
                     VGGQEDMIVDVALDL"
     PFAM_domain     complement(1293..2069)
                     /aSDomain="HMGL-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00682.21"
                     /description="HMGL-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg72_2_0004"
                     /evalue="6.60E-70"
                     /label="ctg72_2"
                     /locus_tag="ctg72_2"
                     /protein_end="261"
                     /protein_start="2"
                     /score="235.7"
                     /tool="antismash"
                     /translation="KIYISDVTLRDGSHAVRHQYTLDNARDIARALDAAKVDSIEVAHG
                     DGLQGSSFNYGFGRHTDLEYIEAVADVVSHAKIATLLLPGIGTVHDLKAAYDAGARVVR
                     VATHCTEADVSKQHIEYARELGMDTVGFLMMSHMIPAEQLAAQGKLMESYGAQCIYMAD
                     SGGAMNMQDIRERMRAFKAVLDPATQTGMHAHHNLSLGVANSIAAVEEGCDRIDASLAG
                     MGAGAGNAPLEVFIAAAERLGWNHGTDLYTLMDAADD"
     CDS             complement(2086..3018)
                     /locus_tag="ctg72_3"
                     /transl_table=11
                     /translation="MSQRKLKVAIIGSGNIGTDLMIKILRQAQHLEMSVMVGIDPNSDG
                     LARAARMGVATTHEGVEGLTRMAQFQDIDFVFDATSAGAHVKNDAFLRAIKPGIRLIDL
                     TPAAIGPYCVPVVNLERNLGQLNVNMVTCGGQATIPMVAAVSRVAKVHYAEIVASIASK
                     SAGPGTRANIDEFTETTSRAIEVIGGAAKGKAIIVMNPAEPPLIMRDTVFVLSEAADQT
                     QVEASIEEMAQAVQAYVPGYRLKQKVQFEPVSELKIPGLGTFTGLKTSVFLEVEGAAHY
                     LPAYAGNLDIMTSAAMATAERMAVSMIAG"
     aSDomain        complement(2095..3006)
                     /aSDomain="TIGR03215"
                     /aSTool="tigrfam"
                     /description="ac_ald_DH_ac: acetaldehyde dehydrogenase
                     (acetylating)"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg72_3_0002"
                     /evalue="5.60E-141"
                     /identifier="TIGR03215"
                     /label="ctg72_3"
                     /locus_tag="ctg72_3"
                     /protein_end="308"
                     /protein_start="4"
                     /score="466.8"
                     /tool="antismash"
                     /translation="KLKVAIIGSGNIGTDLMIKILRQAQHLEMSVMVGIDPNSDGLARA
                     ARMGVATTHEGVEGLTRMAQFQDIDFVFDATSAGAHVKNDAFLRAIKPGIRLIDLTPAA
                     IGPYCVPVVNLERNLGQLNVNMVTCGGQATIPMVAAVSRVAKVHYAEIVASIASKSAGP
                     GTRANIDEFTETTSRAIEVIGGAAKGKAIIVMNPAEPPLIMRDTVFVLSEAADQTQVEA
                     SIEEMAQAVQAYVPGYRLKQKVQFEPVSELKIPGLGTFTGLKTSVFLEVEGAAHYLPAY
                     AGNLDIMTSAAMATAERMAVSMI"
     PFAM_domain     complement(2170..2622)
                     /aSDomain="AcetDehyd-dimer"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09290.13"
                     /description="Prokaryotic acetaldehyde dehydrogenase,
                     dimerisation"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg72_3_0007"
                     /evalue="4.20E-64"
                     /label="ctg72_3"
                     /locus_tag="ctg72_3"
                     /protein_end="283"
                     /protein_start="132"
                     /score="215.0"
                     /tool="antismash"
                     /translation="CGGQATIPMVAAVSRVAKVHYAEIVASIASKSAGPGTRANIDEFT
                     ETTSRAIEVIGGAAKGKAIIVMNPAEPPLIMRDTVFVLSEAADQTQVEASIEEMAQAVQ
                     AYVPGYRLKQKVQFEPVSELKIPGLGTFTGLKTSVFLEVEGAAHYLP"
     PFAM_domain     complement(2659..3000)
                     /aSDomain="Semialdhyde_dh"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01118.26"
                     /description="Semialdehyde dehydrogenase, NAD binding
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg72_3_0006"
                     /evalue="1.00E-11"
                     /label="ctg72_3"
                     /locus_tag="ctg72_3"
                     /protein_end="120"
                     /protein_start="6"
                     /score="45.4"
                     /tool="antismash"
                     /translation="KVAIIGSGNIGTDLMIKILRQAQHLEMSVMVGIDPNSDGLARAAR
                     MGVATTHEGVEGLTRMAQFQDIDFVFDATSAGAHVKNDAFLRAIKPGIRLIDLTPAAIG
                     PYCVPVVNLE"
     CDS             complement(3015..4874)
                     /NRPS_PKS="Domain: AMP-binding (45-470). E-value: 2.6e-61.
                     Score: 199.2. Matches aSDomain:
                     nrpspksdomains_ctg72_4_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     168.1; E-value: 4.2e-51)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg72_4"
                     /sec_met_domain="AMP-binding (E-value: 3.3e-55, bitscore:
                     178.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYDIFNDPTRLAPAHVRCEPGADGSFILSNEETLQPYARCIGEWL
                     ERWAVDRADHPYLAERRNGAWFTLTYQQVRQRVGALAQGLLELDIAPGRPLLMLSENDI
                     DQALLTLAAMHVGIPVSTVSVAYARNTAGGCAKLKAIVEVLDPALIFVNDGDAYCRAIE
                     LVAPRCPVVAARNAQELPDGLALPLLYKTESPAVMQAFARIDGDTPARYLLTSGSTGSP
                     KAVINTHGMLCANQQAIAQCWRFIERIAVVVLDWLPWSHVFGANHNFNLVLRNGGTLYI
                     DDGRPLPGQIDRTVENIKSVRPTLFFNVPRGYEALLPYLERDEELARALFGRLELLFYA
                     AAALPQSSWQRLSARAAEVREAPLFFATEWGSTETSPVVTSVHFQLDKAGNIGLPVPGT
                     QIRFVPSGDKLEMRVKGPSVFPRYLNDAQSTAAAFDELGFYRIGDAGRLVDPERPELGI
                     LFDGRVTEDFKLSSGTWVSVGTLRPRLVSALAPYASDCVICGHDRDVIGALVYPTPALR
                     ELLGKAGQDMSGAELALQAEVRLALCAGLQALARDFPASSQHAARLLILDTPASLNDGE
                     ITDKGYINQRAALTLRAEAVQRLYADTLGQDVILLAEVYGEAV"
     aSDomain        complement(3465..4739)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg72_4_AMP-binding.1"
                     /evalue="2.60E-61"
                     /label="ctg72_4_AMP-binding.1"
                     /locus_tag="ctg72_4"
                     /protein_end="470"
                     /protein_start="45"
                     /score="199.2"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="ERWAVDRADHPYLAERRNGAWFTLTYQQVRQRVGALAQGLLELDI
                     APGRPLLMLSENDIDQALLTLAAMHVGIPVSTVSVAYARNTAGGCAKLKAIVEVLDPAL
                     IFVNDGDAYCRAIELVAPRCPVVAARNAQELPDGLALPLLYKTESPAVMQAFARIDGDT
                     PARYLLTSGSTGSPKAVINTHGMLCANQQAIAQCWRFIERIAVVVLDWLPWSHVFGANH
                     NFNLVLRNGGTLYIDDGRPLPGQIDRTVENIKSVRPTLFFNVPRGYEALLPYLERDEEL
                     ARALFGRLELLFYAAAALPQSSWQRLSARAAEVREAPLFFATEWGSTETSPVVTSVHFQ
                     LDKAGNIGLPVPGTQIRFVPSGDKLEMRVKGPSVFPRYLNDAQSTAAAFDELGFYRIGD
                     AGRLVDPERPELGILFDGRVTEDFKL"
     PFAM_domain     complement(3519..4739)
                     /aSDomain="AMP-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00501.30"
                     /description="AMP-binding enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg72_4_0008"
                     /evalue="1.70E-54"
                     /label="ctg72_4"
                     /locus_tag="ctg72_4"
                     /protein_end="452"
                     /protein_start="45"
                     /score="185.2"
                     /tool="antismash"
                     /translation="ERWAVDRADHPYLAERRNGAWFTLTYQQVRQRVGALAQGLLELDI
                     APGRPLLMLSENDIDQALLTLAAMHVGIPVSTVSVAYARNTAGGCAKLKAIVEVLDPAL
                     IFVNDGDAYCRAIELVAPRCPVVAARNAQELPDGLALPLLYKTESPAVMQAFARIDGDT
                     PARYLLTSGSTGSPKAVINTHGMLCANQQAIAQCWRFIERIAVVVLDWLPWSHVFGANH
                     NFNLVLRNGGTLYIDDGRPLPGQIDRTVENIKSVRPTLFFNVPRGYEALLPYLERDEEL
                     ARALFGRLELLFYAAAALPQSSWQRLSARAAEVREAPLFFATEWGSTETSPVVTSVHFQ
                     LDKAGNIGLPVPGTQIRFVPSGDKLEMRVKGPSVFPRYLNDAQSTAAAFDELGFYRIGD
                     AGRLVDPE"
     CDS_motif       complement(3573..3644)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg72_4_0002"
                     /evalue="1.10E-03"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg72_4"
                     /protein_end="434"
                     /protein_start="410"
                     /score="11.4"
                     /tool="antismash"
                     /translation="EMRVKGPSVFPRYLNDAQSTAAAF"
     CDS_motif       complement(4188..4238)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg72_4_0001"
                     /evalue="1.80E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg72_4"
                     /protein_end="229"
                     /protein_start="212"
                     /score="17.4"
                     /tool="antismash"
                     /translation="LLTSGSTGSPKAVINTH"
     CDS             complement(4977..5759)
                     /locus_tag="ctg72_5"
                     /transl_table=11
                     /translation="MTHPSLHAAAEALARARDSRTPCPRVSERFDIHSLADAYAIQDLN
                     TRVALAAGRRLSGRKIGLTSLAVQQQLGVDQPDFGMLFADMEYRDGDAIDSSRLIQPKA
                     EGEIAFVLGRDLPHVDTTLAELLRAVDHVLPALEIVDSAIEDWKITLVDTVADNASSGL
                     YVLGKTPVSLAGLDLALEGMLLEKNAAQAAIGLGAACMGNPLDACLWLARTMAAAGRPL
                     QAGDVLLSGALGPMVQVQAGDSLRLRLTRLGEVSCRFV"
     PFAM_domain     complement(4983..5459)
                     /aSDomain="FAA_hydrolase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01557.20"
                     /description="Fumarylacetoacetate (FAA) hydrolase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg72_5_0009"
                     /evalue="5.00E-08"
                     /label="ctg72_5"
                     /locus_tag="ctg72_5"
                     /protein_end="259"
                     /protein_start="100"
                     /score="33.2"
                     /tool="antismash"
                     /translation="QPKAEGEIAFVLGRDLPHVDTTLAELLRAVDHVLPALEIVDSAIE
                     DWKITLVDTVADNASSGLYVLGKTPVSLAGLDLALEGMLLEKNAAQAAIGLGAACMGNP
                     LDACLWLARTMAAAGRPLQAGDVLLSGALGPMVQVQAGDSLRLRLTRLGEVSCRF"
     CDS             complement(5772..6743)
                     /locus_tag="ctg72_6"
                     /transl_table=11
                     /translation="MSDRSLSAPQQHLLALFAGLDLPVLAAPMFLVSGPQLVSACCQAG
                     IVGSLPAPNARTVEQLDAWLGEIVAEREAARLRGETRAPWMLNMIVHSTYDRFDAELEL
                     VKRYQPPIVSTALGSPKRVLEAVHAYGGVVIADVISPALARKAADAGVDGLVLVCNGAG
                     GHTGNYNPFAFIGEVRQFWDGPLGLAGAISSGRDIHAAQVLGCDFSLVGTRLVAAAESL
                     VDDAYRDMLVACGLDDIVTTKAVSGVLANWMRPSLEQAGIDPNAESRASIDFSGNIASA
                     NKAWKHVWSAGQGVGQITRRYSVAELVDELHRGYQQSRARAL"
     PFAM_domain     complement(5808..6695)
                     /aSDomain="NMO"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03060.17"
                     /description="Nitronate monooxygenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg72_6_0010"
                     /evalue="1.10E-24"
                     /label="ctg72_6"
                     /locus_tag="ctg72_6"
                     /protein_end="312"
                     /protein_start="16"
                     /score="87.5"
                     /tool="antismash"
                     /translation="FAGLDLPVLAAPMFLVSGPQLVSACCQAGIVGSLPAPNARTVEQL
                     DAWLGEIVAEREAARLRGETRAPWMLNMIVHSTYDRFDAELELVKRYQPPIVSTALGSP
                     KRVLEAVHAYGGVVIADVISPALARKAADAGVDGLVLVCNGAGGHTGNYNPFAFIGEVR
                     QFWDGPLGLAGAISSGRDIHAAQVLGCDFSLVGTRLVAAAESLVDDAYRDMLVACGLDD
                     IVTTKAVSGVLANWMRPSLEQAGIDPNAESRASIDFSGNIASANKAWKHVWSAGQGVGQ
                     ITRRYSVAELVDELH"
     CDS             complement(6786..7598)
                     /NRPS_PKS="Domain: PKS_KR (8-109). E-value: 2.5e-07. Score:
                     22.6. Matches aSDomain: nrpspksdomains_ctg72_7_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     172.7; E-value: 1.6e-52)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg72_7"
                     /transl_table=11
                     /translation="MAWLNNQIALVTGGTGGIGSAIVRRYVAEGAKVAVMGRDAAQLAA
                     LSAELGDSIITVQGDVSRWQDNQRAVAATLEAFGKLDTFVGNAAVFDYFTRLDRIAPED
                     FESAFNTLFSINVQGYLLGAQAATAALRESRGSMIFTLSNSAFYAGGGGILYVTAKHAL
                     VGMIRQLAYELAPDIRVNGVAPGATNTPMKSLEGLNSRSVPLNQIPGFEAGAAAAVPLQ
                     RIAEPEDHTGHYVLLASRENAGLTTANIIHSDGGWEIRGSGAAKHRKT"
     PFAM_domain     complement(7017..7580)
                     /aSDomain="adh_short"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00106.27"
                     /description="short chain dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg72_7_0011"
                     /evalue="2.70E-43"
                     /label="ctg72_7"
                     /locus_tag="ctg72_7"
                     /protein_end="194"
                     /protein_start="6"
                     /score="147.8"
                     /tool="antismash"
                     /translation="QIALVTGGTGGIGSAIVRRYVAEGAKVAVMGRDAAQLAALSAELG
                     DSIITVQGDVSRWQDNQRAVAATLEAFGKLDTFVGNAAVFDYFTRLDRIAPEDFESAFN
                     TLFSINVQGYLLGAQAATAALRESRGSMIFTLSNSAFYAGGGGILYVTAKHALVGMIRQ
                     LAYELAPDIRVNGVAPGATNTPMKS"
     aSDomain        complement(7272..7574)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg72_7_PKS_KR.1"
                     /evalue="2.50E-07"
                     /label="ctg72_7_PKS_KR.1"
                     /locus_tag="ctg72_7"
                     /protein_end="109"
                     /protein_start="8"
                     /score="22.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ALVTGGTGGIGSAIVRRYVAEGAKVAVMGRDAAQLAALSAELGDS
                     IITVQGDVSRWQDNQRAVAATLEAFGKLDTFVGNAAVFDYFTRLDRIAPEDFESAF"
     CDS_motif       complement(7485..7571)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg72_7_0001"
                     /evalue="1.00E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg72_7"
                     /protein_end="38"
                     /protein_start="9"
                     /score="21.4"
                     /tool="antismash"
                     /translation="LVTGGTGGIGSAIVRRYVAEGAKVAVMGR"
     CDS             complement(7764..8294)
                     /locus_tag="ctg72_8"
                     /transl_table=11
                     /translation="MTQTPLDTPLGFDEVRRVEQFLLREARLLDDECWDDWLLTLSEAI
                     HYWMPGIENRRREDKAGPYTLEHMAFFDDGMRELQRRVSRFKQPSAWAENPPTRNVHLV
                     SNIEVYAGDEPGQYRAYSCFINVRSRGLDEQSQITGRREDVLRLEADGLKLLRRKILIP
                     NAMLLCKNINTFL"
     PFAM_domain     complement(7794..8225)
                     /aSDomain="Ring_hydroxyl_B"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00866.20"
                     /description="Ring hydroxylating beta subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg72_8_0012"
                     /evalue="1.60E-40"
                     /label="ctg72_8"
                     /locus_tag="ctg72_8"
                     /protein_end="167"
                     /protein_start="23"
                     /score="138.6"
                     /tool="antismash"
                     /translation="REARLLDDECWDDWLLTLSEAIHYWMPGIENRRREDKAGPYTLEH
                     MAFFDDGMRELQRRVSRFKQPSAWAENPPTRNVHLVSNIEVYAGDEPGQYRAYSCFINV
                     RSRGLDEQSQITGRREDVLRLEADGLKLLRRKILIPNAML"
     CDS             complement(8307..9656)
                     /locus_tag="ctg72_9"
                     /transl_table=11
                     /translation="MDNNKHIPLRTIESTPCLDNLDRICDMEEGRLSGKVFWDQAIYEQ
                     ELEKIFARCWLFVAHESQLPKFGDYLTTSMGEDEVLVVRQKDASLKVFLNACPHRGNKV
                     CFAEAGNARGFICNYHGWSFGADGGRLMGMHESKCYEESHFDKAKHGLREARVATYKGL
                     VFATFAADAPSLEEYLGPMTWYLDVMLDMDEGGSEFLGGCIRSTIDCNWKIAAENFVGD
                     ILHGGWTHDSAAKAMLGGPVANVGELPESYSVNWNGHGYEFATDVVGNAATLGERDINK
                     YLHVLRPKVAERLGEFRSKLIGAISSFTVFPNFSFLPGQNTVRIWQPRGPHKIELFTWV
                     IVNRNAPQEIKDKWRRGAMMTFSPTGVFEMDDGENWEYCTKTAKGVVTRYQDLYVGLGM
                     HTRLDDSELPGNVFKGQLNECNARAFYQRWKDLLQASSWADVPDRNGTLR"
     PFAM_domain     complement(8355..9131)
                     /aSDomain="Ring_hydroxyl_A"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00848.21"
                     /description="Ring hydroxylating alpha subunit (catalytic
                     domain)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg72_9_0014"
                     /evalue="1.20E-24"
                     /label="ctg72_9"
                     /locus_tag="ctg72_9"
                     /protein_end="434"
                     /protein_start="175"
                     /score="87.5"
                     /tool="antismash"
                     /translation="EEYLGPMTWYLDVMLDMDEGGSEFLGGCIRSTIDCNWKIAAENFV
                     GDILHGGWTHDSAAKAMLGGPVANVGELPESYSVNWNGHGYEFATDVVGNAATLGERDI
                     NKYLHVLRPKVAERLGEFRSKLIGAISSFTVFPNFSFLPGQNTVRIWQPRGPHKIELFT
                     WVIVNRNAPQEIKDKWRRGAMMTFSPTGVFEMDDGENWEYCTKTAKGVVTRYQDLYVGL
                     GMHTRLDDSELPGNVFKGQLNECNARAFYQRWKDLLQ"
     PFAM_domain     complement(9270..9494)
                     /aSDomain="Rieske"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00355.28"
                     /description="Rieske [2Fe-2S] domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg72_9_0013"
                     /evalue="1.60E-15"
                     /label="ctg72_9"
                     /locus_tag="ctg72_9"
                     /protein_end="129"
                     /protein_start="54"
                     /score="56.9"
                     /tool="antismash"
                     /translation="WLFVAHESQLPKFGDYLTTSMGEDEVLVVRQKDASLKVFLNACPH
                     RGNKVCFAEAGNARGFICNYHGWSFGADGG"
     CDS             complement(9693..10046)
                     /locus_tag="ctg72_10"
                     /transl_table=11
                     /translation="MSRVLLCQRDELAPGELKKVEQAEGDAICVYNLGGTFYATTDMCT
                     HATASLAEGDLEDDLITCPVHWGQFHIPSGQAVTFPCERHLRTYKIIVTDREVYADVAL
                     EADEAVAAAQSPV"
     PFAM_domain     complement(9777..10037)
                     /aSDomain="Rieske"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00355.28"
                     /description="Rieske [2Fe-2S] domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg72_10_0015"
                     /evalue="8.80E-16"
                     /label="ctg72_10"
                     /locus_tag="ctg72_10"
                     /protein_end="90"
                     /protein_start="3"
                     /score="57.7"
                     /tool="antismash"
                     /translation="VLLCQRDELAPGELKKVEQAEGDAICVYNLGGTFYATTDMCTHAT
                     ASLAEGDLEDDLITCPVHWGQFHIPSGQAVTFPCERHLRTYK"
     CDS             complement(10043..10891)
                     /locus_tag="ctg72_11"
                     /transl_table=11
                     /translation="MGKIVGGFWMPHDPVMFVAPKAPPEAQRDAVWGAYAECARRLAEL
                     EPTAVIIVGCDHYILFGTHCLPRYVIGTGDVDGPIDRLPGLQRQVVKNHEALAGHVVAH
                     GDANGVDWSVARSFTVDHSFSIPHQLVVQPAEQLLGKTLPSIPVYLACGVDPYISLRRS
                     ADLGRQLRAAVESFDADERVVIIGSGGISHWVGTAEMGKVAEDFDREILALGVKGDLAG
                     LCAYSDEEILRRAGNGAMEIRNFACAMAALERPVGEVIAYEAVPAWVTGLGFVELKEAS
                     A"
     PFAM_domain     complement(10076..10870)
                     /aSDomain="LigB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02900.20"
                     /description="Catalytic LigB subunit of aromatic
                     ring-opening dioxygenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg72_11_0016"
                     /evalue="5.30E-33"
                     /label="ctg72_11"
                     /locus_tag="ctg72_11"
                     /protein_end="272"
                     /protein_start="7"
                     /score="114.3"
                     /tool="antismash"
                     /translation="FWMPHDPVMFVAPKAPPEAQRDAVWGAYAECARRLAELEPTAVII
                     VGCDHYILFGTHCLPRYVIGTGDVDGPIDRLPGLQRQVVKNHEALAGHVVAHGDANGVD
                     WSVARSFTVDHSFSIPHQLVVQPAEQLLGKTLPSIPVYLACGVDPYISLRRSADLGRQL
                     RAAVESFDADERVVIIGSGGISHWVGTAEMGKVAEDFDREILALGVKGDLAGLCAYSDE
                     EILRRAGNGAMEIRNFACAMAALERPVGEVIAYEAVPAWVTGL"
     CDS             complement(10896..11192)
                     /locus_tag="ctg72_12"
                     /transl_table=11
                     /translation="MSRNVMERVLWQLCVERAAKERFRQDAAGFLERFELGERERDMIL
                     GFDVAGLQAAGVNPMLTMGFWQELSPERGMTIYKQRLGCTDQDSAGFSAALKG"
     PFAM_domain     complement(11004..11177)
                     /aSDomain="LigA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07746.13"
                     /description="Aromatic-ring-opening dioxygenase LigAB, LigA
                     subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg72_12_0017"
                     /evalue="3.40E-08"
                     /label="ctg72_12"
                     /locus_tag="ctg72_12"
                     /protein_end="63"
                     /protein_start="5"
                     /score="33.6"
                     /tool="antismash"
                     /translation="MERVLWQLCVERAAKERFRQDAAGFLERFELGERERDMILGFDVA
                     GLQAAGVNPMLTM"
     CDS             complement(11198..12013)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262:haloalkane dehalogenase (Score: 138.3; E-value:
                     4.9e-42)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg72_13"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.9e-22, bitscore:
                     71.7, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 2.1e-15, bitscore: 47.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSANAKTLLAAGHNTHYYEAGQGDALFLLHGSGPGVSGWSNWGKS
                     IPVFADRWRVIVPDIAGFGFTEFQDDAKYDIKLWVSHLVGIMDALDIQKASFIGNSFGG
                     AVAIGLAVFAPERVDKLVLLGTPAGEFVQTPGLRGAWEYEPSLDNMRRLMELFPYDKAL
                     ISDEMVRSRYEASARPGAQDALRKLIPQPAAEGETLVKGFPAAALAKISAPTLVVHGRE
                     DRVVPPQCGLLIANSVPNADLHLFGHCGHWVQSEQPRRFAALVRDFLGE"
     PFAM_domain     complement(11225..11938)
                     /aSDomain="Abhydrolase_6"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12697.9"
                     /description="Alpha/beta hydrolase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg72_13_0018"
                     /evalue="1.30E-18"
                     /label="ctg72_13"
                     /locus_tag="ctg72_13"
                     /protein_end="263"
                     /protein_start="25"
                     /score="68.5"
                     /tool="antismash"
                     /translation="LFLLHGSGPGVSGWSNWGKSIPVFADRWRVIVPDIAGFGFTEFQD
                     DAKYDIKLWVSHLVGIMDALDIQKASFIGNSFGGAVAIGLAVFAPERVDKLVLLGTPAG
                     EFVQTPGLRGAWEYEPSLDNMRRLMELFPYDKALISDEMVRSRYEASARPGAQDALRKL
                     IPQPAAEGETLVKGFPAAALAKISAPTLVVHGREDRVVPPQCGLLIANSVPNADLHLFG
                     HCGHWVQSEQPRRFAA"
     CDS             12308..12889
                     /locus_tag="ctg72_14"
                     /transl_table=11
                     /translation="MSSRPNLTREDWIHAAQHVLVSSGVDAVRVDTLAKELKITRGSFY
                     YHFKSRGELLEGILGNWRARATEDVILSLRNAHASPLQQLQRLLELPSHGQTAKDAAAI
                     ELGIRAWARRDKQARQAIDEVDSHRLNYIEGLLIQAGTPVDEAQDRAYLIYAYQISLSL
                     LHGDDSSQQRLERSQRMAGLLLPQGAAVPA"
     PFAM_domain     12344..12475
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00440.25"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg72_14_0019"
                     /evalue="1.40E-09"
                     /label="ctg72_14"
                     /locus_tag="ctg72_14"
                     /protein_end="56"
                     /protein_start="12"
                     /score="37.6"
                     /tool="antismash"
                     /translation="IHAAQHVLVSSGVDAVRVDTLAKELKITRGSFYYHFKSRGELLE"
     CDS             13297..14331
                     /locus_tag="ctg72_15"
                     /transl_table=11
                     /translation="MDLSILAFLGQDGLTTGAIYALVALALVLVFSVTRTILVFQGDFV
                     TYSALTLAMLQTGLLPGTLWLLLGLSLLACALDSALALRHGHYRRLPGLALRYLGLPVV
                     LWLLLGSLDLRALPGLLQIVVTLALVTPLGPLLYRLVYQRVAQTSVLSLLIISVAVHIA
                     LVGISLSLFGAEGVRTHSLADATFMLGDLPVSLQSLLVIACALALIGLLYAFFGHSLYG
                     KALRATALNRDGAQLVGIPTQLAGRSAFALAAFIGAVSGVLIGPLTTLYYDSGFLISLK
                     GFVAAIFGGLASYPIAAASAFFVGVLESFANFGASAFKEVIVFTLVIPVLLWLSLKHPH
                     LEDH"
     PFAM_domain     13333..14286
                     /aSDomain="BPD_transp_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02653.18"
                     /description="Branched-chain amino acid transport system /
                     permease component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg72_15_0020"
                     /evalue="3.10E-15"
                     /label="ctg72_15"
                     /locus_tag="ctg72_15"
                     /protein_end="330"
                     /protein_start="12"
                     /score="56.2"
                     /tool="antismash"
                     /translation="GLTTGAIYALVALALVLVFSVTRTILVFQGDFVTYSALTLAMLQT
                     GLLPGTLWLLLGLSLLACALDSALALRHGHYRRLPGLALRYLGLPVVLWLLLGSLDLRA
                     LPGLLQIVVTLALVTPLGPLLYRLVYQRVAQTSVLSLLIISVAVHIALVGISLSLFGAE
                     GVRTHSLADATFMLGDLPVSLQSLLVIACALALIGLLYAFFGHSLYGKALRATALNRDG
                     AQLVGIPTQLAGRSAFALAAFIGAVSGVLIGPLTTLYYDSGFLISLKGFVAAIFGGLAS
                     YPIAAASAFFVGVLESFANFGASAFKEVIVFTLVIPV"
ORIGIN
        1 cccaagacaa gcacctggcg accttgatgc agtcccccga caagccttcg acgatgctac
       61 ctacacaaac gcatccgcgt ggaaatccac ctccgccagc ccgcgctgcg ccacatactc
      121 gcggcgcgcc gactcgacca cgatcggcgc cccgcaggca tacacctcga agcccttgag
      181 gctatggaag tcctccatca cctggcgatg cacgaagccg gtcgcgccct gccagtcgca
      241 ggactcgccc ggctccgaca gcaccggggt gtagcgcagc catgccagct ccgcctccca
      301 ggccagcaac tgctcgtggc ggtagaggtc ctcacggcgc cgcccgcccc agtacaggta
      361 caccggccgc cgattgccct gctcgcgcag ttgctcgagc aacgcctgga tcggcgcgaa
      421 accggtaccg ctggcaagaa acaccatcgg cgcctcgccc tgacgcagga agaacgaacc
      481 gaacggcccc tccatgcgca ggatcgcctt cggctgcagg gcgttgaaca catgcccgct
      541 gaacaccccg cccggcatgt ggcggatatg cagttccagt tgctgctcac gggcagccgc
      601 ggtagccatg gaatagctgc gccggctgcc gtccttgagc agcacctgca cgtactgtcc
      661 ggggaaataa ctgaaggtgc tgcccggcgc cagcatcaga cgcagcacgg cgacgtcgtg
      721 gctgaccttg tcgatcgccg ccacccgcac gcccatctgc tggatgctga tcccgcgcag
      781 ttcggtgact tccggcgcct cgatcaccag gtccgaccgc gcccgcgcgc agcagaacag
      841 cgccagcccc tgcgcgcgct cggcttcgct gagcacctcc agcgggctgt cggcgtgatc
      901 cacctggcca ctgagcaagc gccccttgca actgccgcag gtgccggtgc ggcaactgtg
      961 cttgagcatc aggccatcgg ccagggcggc gtcgagcacg ctctgctccg gggagaccgg
     1021 gcagctcagg cccaccggct cgatgcgcat ctggaagctc atgacgcgct ccttgccgcc
     1081 agcagatcca gcgccacatc gacgatcatg tcttcctgtc cgccgaccat gcgccgtttg
     1141 cccagctcca cgaggatgtc cacggtcttc aggccgtagc gcttcgcggc gatttccgcg
     1201 tgacggagga agctggagta gacgccggca tagcccagcg ccagcgactc gcggtccacc
     1261 cgcaccgggc ggtcctgcag cggccggacg atatcgtcgg cggcgtccat cagggtgtag
     1321 aggtcggtgc cgtggttcca gcccaggcgt tcggcggcgg cgatgaacac ttccagcggc
     1381 gcgttgcccg cacccgcgcc catcccggcg aggctggcgt cgatgcggtc gcagccctcc
     1441 tccaccgcgg caatggagtt ggccacgccc aggctcaggt tgtggtgcgc gtgcatgccg
     1501 gtctgggtcg ccggatcgag caccgccttg aacgcgcgca tgcgctcacg gatgtcctgc
     1561 atgttcatcg cgccaccgga gtcggccatg tagatgcact gcgcgccgta gctctccatc
     1621 agcttgccct gcgccgccag ctgctcggcg gggatcatgt ggctcatcat caggaagccg
     1681 acggtgtcca tgcccagctc gcgggcgtat tcgatgtgct gcttcgacac gtcggcttcg
     1741 gtgcagtggg tggcgacgcg gaccacgcgg gcgccggcat cgtaggcggc tttcaggtca
     1801 tggaccgtgc cgatgcctgg cagcagcaag gtagcgatct tcgcgtggct gaccacgtcg
     1861 gccaccgcct cgatgtactc caggtcggtg tggcggccga agccgtagtt gaagctggaa
     1921 ccctgcaggc cgtcgccgtg ggccacttcg atggagtcga ctttcgctgc gtccagcgcc
     1981 cgggcgatgt cgcgggcatt gtccagggtg tactgatggc gcacggcatg gctgccgtcg
     2041 cgcagggtga cgtcggagat gtagatcttc ttcatgctct gttcctcagc cggcgatcat
     2101 cgacacggcc atgcgctcgg cagtggccat ggcggcggac gtcatgatgt cgaggttgcc
     2161 ggcgtaggcc ggcaggtaat gggcggcgcc ttcgacttcg aggaacaccg aggtcttcag
     2221 cccggtgaag gtgccgaggc cggggatctt cagctcgctg accggctcga actgcacctt
     2281 ctgcttcagc cgatagccgg gcacgtaggc ctggacggcc tgggccatct cttcgatgga
     2341 ggcctcgact tgggtctggt ccgccgcttc ggagagcacg aacaccgtgt cgcgcatgat
     2401 cagcggcggc tccgccgggt tcatgacgat gatcgccttg cccttggccg caccgccgat
     2461 cacctcgatg gcgcgggagg tggtctcggt gaactcgtcg atattggcgc gggtgccggg
     2521 gccggcggat ttgctggcga tcgaggcgac gatctcggcg tagtggacct tcgccacccg
     2581 cgacaccgcg gccaccatgg ggatggtcgc ctggccgccg caggtgacca tgttgacgtt
     2641 gagctggccg aggttccgct ccaggttcac caccggcacg cagtacgggc cgatggccgc
     2701 cggggtcagg tcgatcaggc gaatgccggg cttgatcgcg cgcaggaagg cgtcgttctt
     2761 cacatgggcg ccggcgctgg tggcatcgaa gacgaaatcg atgtcctgga actgtgccat
     2821 ccgggtcagg ccttccacgc cttcgtgggt cgtggccacg cccatgcgcg cggcacgggc
     2881 cagtccatcg gagttcgggt cgatgccgac catcaccgac atttccaggt gctgcgcctg
     2941 gcgcaggatc ttgatcatca gatcggtgcc gatgttgccg gaaccgatga tggcgacttt
     3001 cagtttgcgt tgactcatac cgcttctccg tagacttcgg cgagcaggat cacgtcctgg
     3061 ccgagggtgt cggcgtacag gcgctggacc gcctcggcgc gcagcgtcag ggcggcgcgc
     3121 tggttgatgt agcccttgtc ggtgatttcg ccgtcgttga ggctcgccgg cgtgtcgagg
     3181 atcaacaacc gcgcggcgtg ctgcgaggag gccgggaagt cccgggccag ggcctgcagg
     3241 ccggcgcaca gggccagacg gacctccgcc tgcagggcca gttcggcgcc gctcatgtcc
     3301 tgcccggcct tgcccagcag ttcgcgcagc gccggggtcg gatagaccag cgcaccgatc
     3361 acgtcgcggt catgcccgca gatcacgcaa tcgctggcat agggcgccag ggcactgacc
     3421 aggcgtggcc gcagggtgcc gaccgagacc caggtgccgc tgctgagctt gaagtcctcg
     3481 gtgacccggc catcgaagag aatgcccagc tccggccgct cgggatcgac caggcgcccg
     3541 gcatcgccga tgcggtagaa gcccagttcg tcgaaggccg ccgcggtgct ctgtgcatcg
     3601 ttgagatagc gcgggaacac cgacggaccc ttcacgcgca tttccagctt gtcgccgctg
     3661 ggcacgaagc ggatctgcgt gcccggtacc ggcaggccga tattgccggc cttgtccagc
     3721 tggaagtgca cgctggtgac caccggcgag gtctcggtcg aaccccattc ggtggcgaag
     3781 aacagcggcg cctcgcgcac ctcggcagcc cgcgcggaca ggcgctgcca ggaactctgc
     3841 ggcaatgcgg cggcggcgta gaacagcagt tcgagacggc cgaacaaggc ccgggccagt
     3901 tcctcgtcgc gctccaggta cggcagcaac gcctcgtagc cccgcggcac gttgaagaac
     3961 agggtcggcc tgaccgactt gatgttctcc acggtgcggt cgatctgccc cggcagcggg
     4021 cgaccgtcgt cgatatacag ggtgccgccg ttgcgcagca ccaggttgaa gttgtggttg
     4081 gcaccgaaca catggctcca cggcagccag tccagcacca ccaccgcgat ccgttcgatg
     4141 aagcgccagc actgggcgat ggcctgctgg ttggcgcaga gcatgccgtg ggtgttgatc
     4201 accgccttgg gcgagccggt ggagccggaa gtcagcaggt agcgcgccgg ggtgtcgccg
     4261 tcgatgcgcg cgaacgcctg catcaccgcc gggctttcgg tcttgtacag cagcggcagg
     4321 gccaggccgt cgggcagctc ctgggcgttg cgcgccgcca ccaccggaca gcgcggggcg
     4381 accagctcga tggcgcggca ataggcatcg ccgtcattga cgaagatcag cgccgggtcg
     4441 agcacctcga cgatggcctt gagcttggcg cagccgccgg cggtattgcg cgcataggcc
     4501 accgacaccg tggacaccgg gatgcccacg tgcatcgccg ccagggtcag cagggcctgg
     4561 tcgatatcgt tttccgagag catcagcagc ggccgccccg gggcgatgtc cagctccagc
     4621 aggccctggg ccagcgcgcc gacgcgctgg cgcacctgct ggtaggtcag ggtgaaccag
     4681 gcgccgttgc gccgctcggc cagataggga tgatccgccc tgtccacggc ccagcgctcc
     4741 agccactcgc cgatgcagcg cgcatagggt tgcagggttt cctcgttgct caggatgaaa
     4801 ctgccgtccg cgccgggctc gcagcgcacg tgcgccggcg ccaaccgcgt cgggtcgttg
     4861 aagatgtcgt acatggcacg ccctcgtggg tccggccggt caggtgcccg ccgcccactg
     4921 gttttattgt tgtgacgtac accggcactg gcggccggcg tgactcgggt caggcttcag
     4981 acgaagcggc agctcacttc gcccagacgg gtcaggcgca ggcgcaggct gtcgccggcc
     5041 tgtacctgga ccatcggccc cagcgccccg gacagcagca catcgccggc ctgcagcgga
     5101 cgtcccgccg cggccatggt ccgcgccagc cacaggcagg catccagcgg attgcccatg
     5161 cacgccgcgc cgagaccgat ggcggcctgg gccgcgttct tctccaggag catgccctcc
     5221 agggccaggt cgaggccggc caggctgacc ggggtcttgc ccagcacata gaggccggac
     5281 gaggcgttgt cggcgacggt gtcgaccagg gtgatcttcc agtcctcgat cgccgaatcg
     5341 acgatttcca gcgccggcag cacatggtcc accgcgcgca gcagctcggc cagggtggtg
     5401 tcgacgtggg gcaggtcgcg gccgagaacg aaggcgatct cgccttccgc cttgggctgg
     5461 atcaggcgac tgctgtcgat ggcatcgccg tcgcggtact ccatgtcggc gaagagcatg
     5521 ccgaagtccg gctggtcgac gcccagttgc tgctgcaccg ccagcgaggt caggccgatc
     5581 ttgcgcccgc tcaggcggcg gcccgcggcc agggcgacgc gggtgttgag gtcctggatg
     5641 gcgtaggcgt cggccaggct gtggatgtcg aagcgttcgg aaacccgcgg gcacggggtc
     5701 cggctgtcgc gcgcgcgggc cagggcctcg gcggcggcgt gcagggacgg atgagtcatg
     5761 gcgatgctcc tttacagcgc gcgggcgcgg ctttgttggt aaccccggtg cagttcgtcg
     5821 accagctcgg cgacgctgta gcgccgggtg atctgcccca ccccctgccc cgccgaccac
     5881 acgtgcttcc aggccttgtt ggcgctggcg atatttccgg agaagtcgat gctggcgcgg
     5941 ctttcggcgt tcgggtcgat cccggcctgc tccagcgatg ggcgcatcca gttggcgagc
     6001 acgccgctga ccgccttggt cgtgacgatg tcgtcgagcc cgcaggccac cagcatgtcg
     6061 cggtaggcat cgtccaccag gctttccgcg gcggcgacca gacgggtgcc gaccagcgag
     6121 aagtcgcagc cgagcacctg cgccgcgtgg atatcgcggc ccgaggaaat cgccccggcc
     6181 agccccagcg ggccgtccca gaactggcgc acctcgccga tgaaggcgaa cgggttgtag
     6241 ttgccggtat gcccgccggc accgttgcac accaggacca ggccatcgac cccggcgtcc
     6301 gccgccttgc gcgccagcgc cgggctgatg acatcggcga tcaccacgcc gccgtaggcg
     6361 tgcacggcct ccagcacgcg cttggggctg cccagggcgg tggaaacgat cggcggctgg
     6421 tagcgcttga ccagttccag ctcggcgtcg aaacggtcgt aggtgctgtg cacgatcatg
     6481 ttcagcatcc acggcgcgcg ggtttcgccg cgcaggcgtg cggcctcgcg ctcggcgacg
     6541 atctcgccga gccaggcatc cagttgctcg acggtgcgcg cgttgggcgc cggcaggctg
     6601 ccgacgatgc cggcctggca gcaggccgag accagttgcg gcccggaaac caggaacatc
     6661 ggcgcggcca gtaccggcag gtcgaggccg gcgaacagcg ccagcaggtg ttgttgcggt
     6721 gcactaaggc ttctgtcgct catcacgcat ctctcttgtt cattttgtcg agcacgcagg
     6781 gtcaatcagg tcttgcggtg tttcgccgcg ccgctgccgc ggatctccca gccaccatcg
     6841 ctgtgaatga tattggcggt ggtcagcccg gcattctccc gcgaggccag cagcacatag
     6901 tggccggtgt gatcctcggg ttcggcgatg cgttgcagcg gaaccgcggc ggcggcaccg
     6961 gcttcgaaac cgggaatctg gttcagcggc acgctgcggc tgttcaggcc ttcgaggctc
     7021 ttcatcggcg tgttggtggc accgggggcg acgccgttga cacggatgtc cggggccagc
     7081 tcgtaggcca gctgacggat catgccgacc agggcgtgct tggcggtgac atagagaatg
     7141 ccaccaccac cggcatagaa ggcactgttg gacagggtga agatcatgct gccgcggctt
     7201 tcgcgcaagg ccgcggtcgc cgcctgggcg ccgagcaggt agccctggac gttgatcgag
     7261 aacagcgtgt tgaaggcgct ttcgaaatct tccggggcga tgcggtcgag ccgggtgaaa
     7321 tagtcgaaca ccgcggcatt gccgacgaag gtgtcgagct tgccgaaggc ttcgagggtc
     7381 gccgccacgg cgcgctggtt gtcctgccag cgcgagacat cgccctgcac ggtgatgatg
     7441 gaatcgccca gttcggcgga cagcgccgcc agttgcgcgg cgtcgcggcc catgacggcg
     7501 accttcgccc cttcggcgac atagcgccgc acgatggcgc tgccgatacc gccggtgccg
     7561 ccggtgacca gggcgatctg gttgttcagc caagccatgt ttcagtcctc gataaaaatg
     7621 accttcttgc ctccgcctcc ccgtaggagc gtggcttgcc cgcgaaggac cgcgcagcgg
     7681 tccccgactt gactgctatc gggaccgctt tgcggtcctt cgcgggcaag ccacgctcct
     7741 acgggacatg agcaaccttc acgtcacagg aaggtattga tgttcttgca cagcaacatc
     7801 gcgttgggga tcaggatctt gcgccgcagc agcttcaacc cgtccgcttc caggcgcagc
     7861 acgtcctcgc gccgcccggt gatctgcgac tgctcgtcga gcccgcggct gcgcacgttg
     7921 atgaagcagg aataggcccg gtactgcccc ggctcgtcac cggcatacac ctcgatattg
     7981 ctcaccaggt gcacgttgcg cgtcggcggg ttctcggccc aggccgaggg ttgcttgaaa
     8041 cgcgacacgc ggcgctgcag ctcgcgcatg ccgtcatcga agaaggccat gtgctccagg
     8101 gtgtagggtc cggccttgtc ctcgcggcgg cggttctcga tgccgggcat ccagtagtga
     8161 atcgcctcgc tcagggtcag cagccagtcg tcccagcatt cgtcatccag caggcgcgct
     8221 tcgcgcagca ggaactgctc gacccggcgc acttcgtcga agcccagcgg ggtgtccagt
     8281 ggtgtctgtg tcattcctcg tgctcctcag cgcagggtgc cgttgcggtc cggcacatcg
     8341 gcccagctgg acgcctgcag caggtccttc cagcgctggt agaacgcccg cgcgttgcat
     8401 tcgttgagct ggcccttgaa cacattgccc ggcagctcgc tgtcgtcgag gcgggtgtgc
     8461 atgcccaggc ccacgtacag gtcctggtag cgggtcacca cgcccttggc ggtcttggtg
     8521 cagtactccc agttctcgcc gtcgtccatc tcgaacacgc cggtgggcga gaaggtcatc
     8581 atcgcgccgc ggcgccactt gtccttgatc tcctggggcg cgttcctgtt gacgatgacc
     8641 caggtgaaca gctcgatctt gtgcggcccg cgcggttgcc agatgcgcac ggtgttctgc
     8701 cccggcagga aggagaagtt ggggaacacg gtgaacgagg aaatcgcccc gatcagcttc
     8761 gagcggaact cgcccagacg ctccgccacc ttgggccgca gcacatgcag gtacttgttg
     8821 atgtcgcgct cgccgagggt cgcggcattg cccaccacgt cggtggcgaa ttcgtagccg
     8881 tggccgttcc agttcaccga ataggattcc ggcagctcgc cgacattggc caccggcccg
     8941 ccgagcatgg ccttggccgc cgaatcgtgg gtccagccgc catggaggat atcgccgacg
     9001 aagttttccg cggcgatctt ccagttgcag tcgatggtgg aacggatgca gccgccaagg
     9061 aactcgctgc cgccctcgtc catgtcgagc atcacgtcca ggtaccaggt catcggcccg
     9121 aggtattcct cgaggctcgg cgcatcggcg gcgaaggtgg cgaacaccag gcccttgtag
     9181 gtggcgaccc gggcctcgcg caggccgtgt ttcgccttgt cgaagtggct ttcttcgtag
     9241 cacttggact cgtgcatgcc catcagtcgg ccaccgtcgg cgccgaacga ccagccgtgg
     9301 tagttgcaga tgaaaccgcg ggcattgccg gcctcggcga agcagacctt gttgccgcgg
     9361 tgcgggcagg cgttgaggaa gaccttcagc gaggcgtcct tctgccgcac caccagcacc
     9421 tcgtcctcgc ccatggaggt ggtcaggtag tcgccgaact tcggcagttg cgattcgtgg
     9481 gcgacgaaca gccagcagcg ggcgaagatc ttctccagct cctgctcgta gatcgcctgg
     9541 tcccagaaca ccttgccgga caggcggccc tcttccatgt cgcagatgcg gtcgaggttg
     9601 tccaggcagg gcgtggattc gatggttctg agcggaatgt gcttgttgtt atccatggtt
     9661 cagactcacg gggaattcgg ttggacggcg gatcagaccg ggctctgggc ggcggccacg
     9721 gcctcgtcgg cttccagggc gacgtcggcg tagacctcgc ggtcggtgac gatgatcttg
     9781 taggtgcgca ggtgccgttc gcaggggaag gtcaccgcct gcccgctggg gatatggaac
     9841 tggccccagt gcaccgggca ggtgatcagg tcgtcttcca ggtcgccctc ggccagcgaa
     9901 gcggtggcgt gggtgcacat gtcggtggtg gcgtagaagg tgccgccgag gttgtagacg
     9961 cagatggcgt cgccttcggc ctgctcgacc ttcttcagtt cgccgggggc cagctcgtcg
    10021 cgctggcaca gcagtacgcg gctcatgccg atgcctcctt cagttcaacg aagcccaggc
    10081 cggtgaccca ggccggcacc gcctcgtagg cgatgacttc gcccaccggc cgttccagcg
    10141 cggccatggc gcaggcgaaa ttgcggattt ccatggcgcc gttgccggcg cggcggagaa
    10201 tctcctcgtc gctgtaggcg cagagcccgg ccaggtcgcc cttgacccca agggcgagaa
    10261 tctcgcggtc gaagtcctcg gcgaccttgc ccatctcggc ggtgccgacc cagtggctga
    10321 tgccgccgct gccgatgatc accacacgct cgtcggcgtc gaaggactcc accgccgcgc
    10381 gcagctgccg gcccaggtcg gccgagcgcc gcagcgagat atagggatcg acgccgcagg
    10441 ccaggtacac cgggatgctc ggcagggtct tgcccagcaa ctgctcggcc ggctgcacca
    10501 ccagttggtg cgggatggag aacgagtggt cgacggtgaa gctgcgcgcc acgctccagt
    10561 ccacgccatt ggcatcgcca tgggcgacga catgcccggc cagggcctcg tggttcttca
    10621 ccacctggcg ctgcaggccc ggcaggcggt cgatcggccc gtcgacatcg ccggtgccga
    10681 tcacatagcg cggcaggcaa tgggtgccga acagaatgta gtggtcgcaa cccacgatga
    10741 tcaccgcggt cggttccagc tcggcgaggc gccgcgcgca ttcggcgtag gcaccccaca
    10801 cggcgtcgcg ctgggcttcg ggcggcgcct tgggcgccac gaacatcacc gggtcatgcg
    10861 gcatccagaa gccgccaact atcttgccca tctcgtcacc ccttgagcgc ggcggagaac
    10921 cccgcgctgt cctggtcggt gcagcccaga cgctgcttgt agatcgtcat gccgcgctcg
    10981 ggcgaaagct cctgccagaa gcccatggtc agcatcgggt tgaccccggc ggcctgcagg
    11041 ccggcgacat cgaaaccgag gatcatgtcg cgctcccgtt cacccagttc gaagcgttcg
    11101 agaaagccgg cggcgtcctg gcgaaagcgt tctttcgccg cgcgctcgac gcagagttgc
    11161 cagagcaccc gttccatcac gtttcggctc atggcggtca ctcgccgagg aaatcgcgga
    11221 ccagcgcggc gaaacgccgg ggctgctcgc tctggaccca gtggccgcag tggccgaaca
    11281 ggtgcaggtc ggcgttgggc acgctgttgg cgatcagcag gccgcactgc ggcggcacca
    11341 cgcggtcttc gcgaccgtgg accaccaggg tcggcgcgct gatcttcgcc agggcggcgg
    11401 ctgggaagcc cttgaccagg gtttcgcctt cggcggccgg ttgcggaatc agcttgcgca
    11461 gggcgtcctg ggcccccggc cgggcgctgg cctcatagcg cgaccggacc atttcgtcgc
    11521 tgatcagggc cttgtcgtaa gggaacagct ccatcagccg gcgcatgttg tccagcgatg
    11581 gctcgtactc ccaggcgccg cgcaggccgg gggtctgcac gaattcaccg gcgggggtgc
    11641 cgagcagcac cagcttgtcg acccgctccg gggcgaacac ggccaggccg atggccaccg
    11701 cgccgccgaa ggagttgccg atgaacgaag ccttctggat atccagggca tccatgatgc
    11761 cgaccaggtg actgacccag agcttgatgt cgtacttcgc gtcgtcctgg aactcggtga
    11821 aaccgaagcc ggcgatgtcc ggcacgatca cccgccagcg gtcggcgaat acaggaatgc
    11881 tttttcccca gttgctccag ccggacacgc ccgggccgga accgtgcagc aggaacaggg
    11941 catcgccctg gccagcctcg tagtagtggg tgttgtgccc tgcggccagc aacgtcttgg
    12001 cgtttgcgct catcgcggtc tccgttttta ttctcaacat acacatctgt atctagatgc
    12061 tagggagggt tttgacgtgc gtcaacgaaa aaaacctgga accgtgcaaa ataatgggga
    12121 tcaacctaca gatgtgtatt tcaagaaacg agggaattcg gcacactgcc agggccccgg
    12181 gccgcgtcca gcaagccccg gcggcgatag cctcggcatt gcgccgggcg ctagaatgcc
    12241 ctccttcgcg ccctcggcct gtgccgcccc ggcgcctgac ccgttcgatg aacaaggccc
    12301 tacaacgatg tcatcacgcc ccaacctcac ccgcgaagac tggattcacg ccgcccaaca
    12361 cgtgctggtc agcagcggtg tcgacgcggt ccgggtcgat accctggcca aggaactgaa
    12421 aatcacccgc ggcagcttct actaccactt caagagccgt ggcgaactgc tcgaaggcat
    12481 cctcggcaac tggcgcgccc gcgccaccga agacgtcatc ctcagcctgc gcaacgccca
    12541 cgcctcgccg ctgcagcagc tgcagcgcct gctggagctg ccgtcccacg gccagaccgc
    12601 caaggatgcc gcggccatcg aactgggcat ccgcgcctgg gcccgccgcg acaaacaggc
    12661 gcgccaggcg atcgacgagg tggacagcca tcgcctgaac tacatcgagg gcctgctgat
    12721 ccaggcggga acgccggtgg acgaggcgca ggaccgggcc tacctgatct atgcgtacca
    12781 gatcagcctg tcgctgctgc atggcgacga cagctcgcag caacgcctgg agcgcagcca
    12841 gcgcatggcc ggcctgctgc tgccgcaggg ggcggcggtg ccggcctgac gccatcttgc
    12901 tggcggttaa taccctcgta ggagcgcggc ttgcccgcga aaggaccgca aagcggtccc
    12961 agatcacttt gggaccgctt tgcggtcctt tcgcgggcaa gccgcgctcc tacgagggct
    13021 atgcgcgtct aaaaatacac aactgtatcc tctgatttca aaaccccacc tttcctcatt
    13081 cccctcttga caaccctcct tcatgacccg ctagtctata catacacatt cacatgtgta
    13141 ttttgaacga atgacctacg gcccctgcca gggctggaac gtacaacaac aaaaatacat
    13201 tcaggtatct cgccatgcgc tcacctacgt gccccggcag ggtcgtcccc tgctcgcccc
    13261 cacttcccta ccccaccgct cgctgagggc aaccccatgg atctctcgat actggctttc
    13321 ctcggccagg acggcctgac cacgggcgcg atctatgcgc tggtggccct ggccctggtc
    13381 ctggtgttct cggtcacccg caccatcctg gtgttccagg gcgacttcgt gacctacagc
    13441 gccctgaccc tggccatgct gcagaccggc ctgctgcccg gcaccctgtg gctgctgctc
    13501 ggcctgtcgc tgctggcctg cgcactggat agcgcactcg ccctgcgcca cggccattac
    13561 cgccgcctgc cggggctggc cctgcgctac ctgggcctgc cggtcgtgct ctggctgctg
    13621 ctcggcagcc tcgacctgcg cgccttgccc ggcctgctgc agatcgtcgt caccctggcc
    13681 ctggtcaccc cgctgggccc gctgctctac cgcctggtct accagcgcgt ggcgcagact
    13741 tcggtgctgt cgctgctgat catctcggtg gcggtgcaca tcgccctggt cggcatcagc
    13801 ctgtcgctgt tcggtgccga gggcgtgcgc acccactccc tggccgacgc cacgttcatg
    13861 ctcggcgacc tgcccgtgag cctgcagagc ctgctggtga tcgcctgtgc cctggccctg
    13921 atcggcctgc tctacgcctt cttcggccac agcctgtacg gcaaggccct gcgcgccacc
    13981 gcactgaacc gcgacggcgc gcaactggtg ggcattccca cgcaactggc cggacgcagc
    14041 gccttcgccc tcgccgcctt catcggcgcg gtgtccgggg tgctgatcgg gccactgacc
    14101 acgctgtact acgactccgg cttcctcatc agcctcaagg gcttcgtcgc cgcgatcttc
    14161 ggcggcctgg ccagctaccc catcgccgcc gccagcgcct tcttcgtcgg cgtgctggag
    14221 agcttcgcca acttcggcgc ctcggccttc aaggaagtca tcgtgttcac cctggtgatc
    14281 ccggtgctgc tgtggctgtc gctgaaacac ccgcatctgg aggaccactg atgcgccgtc
    14341 gcctcgttcc cctgattctg ctgctggccg ccatggccct ggcgccgctg gtactgccgc
    14401 cgttccaggt caccctgctc aactacatcg gcctgtacag cctggtcgcc cttggcctgg
    14461 tgctgctcac cggcatcggc ggcatgacct ccttcggcca ggccgccttc gtcggcatcg
    14521 gcgcctatgc cacggcggtg ctcagtaccg actacggtct gtcgccctgg ctcggcctgc
    14581 tcgccggcct gggcatcacc ctgctggtcg ccacctgcct cggcctgctg accctgcgcc
    14641 tggccgggca ctacctgccg atcggcaccc tggcctgggg cctggcgctg ttctacctgt
    14701 tcggcaacct gccggggctc ggcggcttcg gcggcatcca ggacctgccg gcgatcgagc
    14761 tgttcggctg gacgatcagc gccgcggggg acttcagcgt gctgctcggg gtgatcctgg
    14821 tcgccagcct gtggctgctc gccaacctcc tcgacagccg tcagggtcgt gcca
//
