LOCUS       c00001_NZ_SJPG..       10849 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_SJPG01000001.1 Rubinisphaera italica strain Pan54
            Pan54_contig00001, whole genome shotgun sequence.
ACCESSION   NZ_SJPG01000001
VERSION     NZ_SJPG01000001
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 16:12:36
            Original ID  :: NZ_SJPG01000001.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2180079
            Orig. end    :: 2190928
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10849
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[2185079:2185928](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5849)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10849
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10849
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="5"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(88..888)
                     /locus_tag="ctg1_1692"
                     /transl_table=11
                     /translation="MGRIETVVRRFIGLNALKPFRCQLRSWDRIDTVALLGHSVATTPP
                     LRMPHPKIPGFITRANAQKTYRRSKASFIRDIDSAFDRNDLSFLNHFRVALNDGTQLNG
                     KEATKEALLTLQAKQPRWYVEVAFLESRYWDGPDTQTPEKESEDKSSVEPIEDGLDSGL
                     QHRLDLAEQQIASQDQTIVNLEADKRFLQSELENRRGEIDKLRGFFESVGDAADSTAKL
                     RNSGEPREVLEVSSKPIGKSPREGSRLVRHLPTFHRFFQSVISR"
     CDS             1293..1499
                     /locus_tag="ctg1_1693"
                     /transl_table=11
                     /translation="MTAKKPTANRKRRVEDTVPDGAPDWVTEELILETLDTWQPYYGGS
                     LTAEDALEILLGVTKLFEFIHEM"
     CDS             1527..3020
                     /locus_tag="ctg1_1694"
                     /transl_table=11
                     /translation="MTKRFVALARVSSREQEREGFSLEVQEEALERYAEIQDGKIVRLF
                     RIAETATKSEERRSFKTLLDYCKKNAAKLDALLFFKVDRAARNLFDYVELERLEADYGL
                     PVEYITQQTENTPAGRMMRRTLANMASFYTEQQSIDVKDGLHRRVRSGLFVGKAPYGYV
                     NVRREGRSLVDIDEEKAKRVRRIFELYAFHGHTLDSLVDQLDEEGIPYTASQRRFARSK
                     LHNILRDRAYIGELKYHDEWYPGTHRPIVDRGTFDRVQVLMGEQTYQSHELLYAGELIT
                     CGHCGRPITGEVKQKKTKRGTSTYRYYRCARYTKGDHPRIRIREEKIEEQVLAMFEQLK
                     VQDEKVRRWFANALRARSKDQQSQATEKVEDLQEQITRLNKQLDQLLNLRLLEEIDEST
                     FASKHRELRDRISSMTLKVEAMNRSKSEKADVAVKAFELSQTLSEKWVNADTRAKRQIL
                     EILCLNFSLDDVTLVPEWRKPFDVLAEGLDSENSRDDKI"
     PFAM_domain     1542..1982
                     /aSDomain="Resolvase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00239.23"
                     /description="Resolvase, N terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1694_0076"
                     /evalue="1.20E-20"
                     /label="ctg1_1694"
                     /locus_tag="ctg1_1694"
                     /protein_end="152"
                     /protein_start="5"
                     /score="74.2"
                     /tool="antismash"
                     /translation="VALARVSSREQEREGFSLEVQEEALERYAEIQDGKIVRLFRIAET
                     ATKSEERRSFKTLLDYCKKNAAKLDALLFFKVDRAARNLFDYVELERLEADYGLPVEYI
                     TQQTENTPAGRMMRRTLANMASFYTEQQSIDVKDGLHRRVRSG"
     PFAM_domain     2055..2315
                     /aSDomain="Recombinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07508.15"
                     /description="Recombinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1694_0077"
                     /evalue="6.70E-14"
                     /label="ctg1_1694"
                     /locus_tag="ctg1_1694"
                     /protein_end="263"
                     /protein_start="176"
                     /score="52.2"
                     /tool="antismash"
                     /translation="EEKAKRVRRIFELYAFHGHTLDSLVDQLDEEGIPYTASQRRFARS
                     KLHNILRDRAYIGELKYHDEWYPGTHRPIVDRGTFDRVQVLM"
     PFAM_domain     2361..2531
                     /aSDomain="Zn_ribbon_recom"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13408.8"
                     /description="Recombinase zinc beta ribbon domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1694_0078"
                     /evalue="2.50E-10"
                     /label="ctg1_1694"
                     /locus_tag="ctg1_1694"
                     /protein_end="335"
                     /protein_start="278"
                     /score="40.8"
                     /tool="antismash"
                     /translation="LITCGHCGRPITGEVKQKKTKRGTSTYRYYRCARYTKGDHPRIRI
                     REEKIEEQVLAM"
     CDS             complement(3196..4080)
                     /locus_tag="ctg1_1695"
                     /transl_table=11
                     /translation="MESPTAILPDGLPPKATVFGELFGLIHQNRWPVILAYVLLVVENL
                     LRLAQPFLLGQAVNGLLTNSYLGLWWFLGGHASHMFVQFARQMYDTRVYSHMYAKRVTN
                     LVCYQREAKVPTSRVAARAALSRQFITFVEQQVPKLVSALFSCVGAIAMLFYYDWRIVI
                     ACLVIALPVFVLNYIYSHSVKGVSRVLHDRWEDEVEIIEKASDEEVATHYNGMTSCWVK
                     MSDLEARTTGLTEFFVMGLMAFALLTICRIPGILAGDIFAVFRYLMMFVMGIDTIPRLV
                     EQFARLKDIVQRL"
     PFAM_domain     complement(3325..4008)
                     /aSDomain="ABC_membrane_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13748.8"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1695_0079"
                     /evalue="2.60E-37"
                     /label="ctg1_1695"
                     /locus_tag="ctg1_1695"
                     /protein_end="252"
                     /protein_start="24"
                     /score="128.6"
                     /tool="antismash"
                     /translation="LIHQNRWPVILAYVLLVVENLLRLAQPFLLGQAVNGLLTNSYLGL
                     WWFLGGHASHMFVQFARQMYDTRVYSHMYAKRVTNLVCYQREAKVPTSRVAARAALSRQ
                     FITFVEQQVPKLVSALFSCVGAIAMLFYYDWRIVIACLVIALPVFVLNYIYSHSVKGVS
                     RVLHDRWEDEVEIIEKASDEEVATHYNGMTSCWVKMSDLEARTTGLTEFFVMGLMAFAL
                     LTICRI"
     CDS             complement(4186..5004)
                     /locus_tag="ctg1_1696"
                     /transl_table=11
                     /translation="MNLPEKNMTEENMTEETKPLSPEAAEMQYRDMIQKVARAIAQNRT
                     DDVLPYLGKKYEAKHVEMFIDGNYDKRIDVLIRLMPFVSEDEDFENFEELAMQFADSKQ
                     VRSYEGSTEECDAMLEWLEETQNLTLEQQDTVACQRARYDVEHQARANRSKHIRFQELV
                     TVAVELLEQLGDNDELTIHVNPAVSWSYLKSKKFLDEDESPPVSALYYADDDEVRTAMF
                     EPAGQILLDRLIDLSPCHFSQWAALADEIDPAELKDFAKGLTQLHLIAFS"
     CDS             complement(5001..5849)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1697"
                     /sec_met_domain="DUF692 (E-value: 1.3e-50, bitscore: 170.3,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMPAIGYAVRRENRFILTDPKLNAAEITFEHADLPLWTKNFIGGD
                     EIDYVAVHALKLSVGSPDPPGREYLETLKQVAIENNATSISDHLGFTRDGDDGVEMGHF
                     APVPLTPTALDVTCRNINYVQEFLAPFPFYIETIAYLFQLEGTMTEPEFLIEMFKRTGC
                     GWLLDVTNVYANARNFGFDAKEFVAEVMPHASRVQMHLAGGFWDEEQQLYFDTHSQPIP
                     DDVWELYEYSLNLGKGKVDAVFIERDAEFPGEQEWRRELHKMYDIADASSKGQAFAGSA
                     G"
     PFAM_domain     complement(5049..5702)
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1697_0080"
                     /evalue="1.80E-56"
                     /label="ctg1_1697"
                     /locus_tag="ctg1_1697"
                     /protein_end="267"
                     /protein_start="49"
                     /score="191.4"
                     /tool="antismash"
                     /translation="VAVHALKLSVGSPDPPGREYLETLKQVAIENNATSISDHLGFTRD
                     GDDGVEMGHFAPVPLTPTALDVTCRNINYVQEFLAPFPFYIETIAYLFQLEGTMTEPEF
                     LIEMFKRTGCGWLLDVTNVYANARNFGFDAKEFVAEVMPHASRVQMHLAGGFWDEEQQL
                     YFDTHSQPIPDDVWELYEYSLNLGKGKVDAVFIERDAEFPGEQEWRRELHKMYDI"
     aSDomain        6579..7742
                     /aSDomain="TIGR03440"
                     /aSTool="tigrfam"
                     /description="egtB_TIGR03440: ergothioneine biosynthesis
                     protein EgtB"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1698_0018"
                     /evalue="2.80E-157"
                     /identifier="TIGR03440"
                     /label="ctg1_1698"
                     /locus_tag="ctg1_1698"
                     /protein_end="388"
                     /protein_start="0"
                     /score="522.2"
                     /tool="antismash"
                     /translation="MPDASPLRWHLAHTTWFFETFLLKEILSSYEPWNPHFEVLFNSYY
                     NSVGEQFPRANRGLLTRPSVQEIFEYRHKIDEIILQLIKTESLHHDALRILEIGLQHEQ
                     QHQELMLTDLKHMFSCNPLFPIYRTQKSVNQNWNSPERKWIAHEEGLYEIGARQREFCY
                     DNELPRHRQFVESFSLSNRLVTNAEYLVFIEEGGYRRPEFWLSMGWQAVESQKWSSPLY
                     WHQTDDGWSQFTLSGLRSIDGQEPVTHVSYFEADAYARWAGCRLPEEAEWEIAAEDSVD
                     KYPELIVQGNYVESEKYHPQICSNEGAGSAYQQLFGDVWEWTRSQYSAYPGYHTPEGAI
                     GEYNGKFMCNQFVLRGGSCATSASHIRSSYRNFFPPETRWQFSGIRLA"
     CDS             6579..7748
                     /gene_functions="other (smcogs) SMCOG1226:hypothetical
                     protein (Score: 118.4; E-value: 7.1e-36)"
                     /gene_kind="other"
                     /locus_tag="ctg1_1698"
                     /transl_table=11
                     /translation="MPDASPLRWHLAHTTWFFETFLLKEILSSYEPWNPHFEVLFNSYY
                     NSVGEQFPRANRGLLTRPSVQEIFEYRHKIDEIILQLIKTESLHHDALRILEIGLQHEQ
                     QHQELMLTDLKHMFSCNPLFPIYRTQKSVNQNWNSPERKWIAHEEGLYEIGARQREFCY
                     DNELPRHRQFVESFSLSNRLVTNAEYLVFIEEGGYRRPEFWLSMGWQAVESQKWSSPLY
                     WHQTDDGWSQFTLSGLRSIDGQEPVTHVSYFEADAYARWAGCRLPEEAEWEIAAEDSVD
                     KYPELIVQGNYVESEKYHPQICSNEGAGSAYQQLFGDVWEWTRSQYSAYPGYHTPEGAI
                     GEYNGKFMCNQFVLRGGSCATSASHIRSSYRNFFPPETRWQFSGIRLAK"
     PFAM_domain     7005..7745
                     /aSDomain="FGE-sulfatase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03781.18"
                     /description="Sulfatase-modifying factor enzyme 1"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1698_0081"
                     /evalue="2.90E-33"
                     /label="ctg1_1698"
                     /locus_tag="ctg1_1698"
                     /protein_end="389"
                     /protein_start="142"
                     /score="115.7"
                     /tool="antismash"
                     /translation="KWIAHEEGLYEIGARQREFCYDNELPRHRQFVESFSLSNRLVTNA
                     EYLVFIEEGGYRRPEFWLSMGWQAVESQKWSSPLYWHQTDDGWSQFTLSGLRSIDGQEP
                     VTHVSYFEADAYARWAGCRLPEEAEWEIAAEDSVDKYPELIVQGNYVESEKYHPQICSN
                     EGAGSAYQQLFGDVWEWTRSQYSAYPGYHTPEGAIGEYNGKFMCNQFVLRGGSCATSAS
                     HIRSSYRNFFPPETRWQFSGIRLAK"
     CDS             7794..8756
                     /locus_tag="ctg1_1699"
                     /transl_table=11
                     /translation="MTDYNTITLQDSAETTEFYADVISGLNSKPKTLPSKYFYDEQGSM
                     LFDQICDLDEYYITRTESQIMDRYAHDMARTLGEKIALIELGSGSSRKTRLLLEEVAES
                     TVYMPVDISREHLFKSAEQLAFDFPDLSIKPIHADFTQPIKLDNQIEDDYRKVVYFPGS
                     TIGNFEPEQAVQLLSNISNLVDPDGGLLIGYDLIKDLNILEDAYNDSAGVTAAFNKNLL
                     HRINQELDGNFDLDAFEHQAIFNPEEHRIEMHLISLKKQSVNIGESTFHFEKQESICTE
                     YSHKYSMDSFREMALKAGFHEDRCWTDPNQYFAVCNYRL"
     aSDomain        7845..8741
                     /aSDomain="TIGR03438"
                     /aSTool="tigrfam"
                     /description="egtD_ergothio: dimethylhistidine
                     N-methyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1699_0019"
                     /evalue="4.30E-124"
                     /identifier="TIGR03438"
                     /label="ctg1_1699"
                     /locus_tag="ctg1_1699"
                     /protein_end="316"
                     /protein_start="17"
                     /score="411.6"
                     /tool="antismash"
                     /translation="FYADVISGLNSKPKTLPSKYFYDEQGSMLFDQICDLDEYYITRTE
                     SQIMDRYAHDMARTLGEKIALIELGSGSSRKTRLLLEEVAESTVYMPVDISREHLFKSA
                     EQLAFDFPDLSIKPIHADFTQPIKLDNQIEDDYRKVVYFPGSTIGNFEPEQAVQLLSNI
                     SNLVDPDGGLLIGYDLIKDLNILEDAYNDSAGVTAAFNKNLLHRINQELDGNFDLDAFE
                     HQAIFNPEEHRIEMHLISLKKQSVNIGESTFHFEKQESICTEYSHKYSMDSFREMALKA
                     GFHEDRCWTDPNQYFAVC"
     PFAM_domain     7848..8741
                     /aSDomain="Methyltransf_33"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10017.11"
                     /description="Histidine-specific methyltransferase,
                     SAM-dependent"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1699_0082"
                     /evalue="2.00E-108"
                     /label="ctg1_1699"
                     /locus_tag="ctg1_1699"
                     /protein_end="316"
                     /protein_start="18"
                     /score="362.3"
                     /tool="antismash"
                     /translation="YADVISGLNSKPKTLPSKYFYDEQGSMLFDQICDLDEYYITRTES
                     QIMDRYAHDMARTLGEKIALIELGSGSSRKTRLLLEEVAESTVYMPVDISREHLFKSAE
                     QLAFDFPDLSIKPIHADFTQPIKLDNQIEDDYRKVVYFPGSTIGNFEPEQAVQLLSNIS
                     NLVDPDGGLLIGYDLIKDLNILEDAYNDSAGVTAAFNKNLLHRINQELDGNFDLDAFEH
                     QAIFNPEEHRIEMHLISLKKQSVNIGESTFHFEKQESICTEYSHKYSMDSFREMALKAG
                     FHEDRCWTDPNQYFAVC"
     CDS             8924..9958
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1700"
                     /sec_met_domain="Peptidase_S9 (E-value: 7.7e-13, bitscore:
                     46.7, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHRFQLTNQFLLSRNILLVTFAVLIISTAGQFNLNAAELPKLTKM
                     TFQSSLDDSTQPALIWIPPKAMQEPTPLFIFLHSWSGDYKQNNNVWFAQAVARNWIYLH
                     PNFRGRNDNPASCGSELARQDILDCIQKVIDSTEVDTSRIYLAGSSGGGHMSMLMAGYY
                     PDRFSAVSAWVGISDLAEWYRFHSRGGKPSNYARMVQASTQGVPGQSPEVDAQYKARSP
                     IFHIQNVGDLPLDLNTGIHDGHTGSVPIVHTINAFNKIAQEKQAPLISPEEIETLSQEQ
                     PLSNPQPSDIVPTTEYDTRIYLRRHAGETRVTVFEGGHESIPVPACRWLSKQERKTEWV
                     KSKE"
     PFAM_domain     9293..9712
                     /aSDomain="Peptidase_S9"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00326.23"
                     /description="Prolyl oligopeptidase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1700_0083"
                     /evalue="4.30E-12"
                     /label="ctg1_1700"
                     /locus_tag="ctg1_1700"
                     /protein_end="263"
                     /protein_start="123"
                     /score="46.1"
                     /tool="antismash"
                     /translation="QDILDCIQKVIDSTEVDTSRIYLAGSSGGGHMSMLMAGYYPDRFS
                     AVSAWVGISDLAEWYRFHSRGGKPSNYARMVQASTQGVPGQSPEVDAQYKARSPIFHIQ
                     NVGDLPLDLNTGIHDGHTGSVPIVHTINAFNKIAQE"
ORIGIN
        1 acaaacatca aagaattggt tcggacaata aacatagttt gagttcaacg gttcaaagcc
       61 agagaatggt gcctcctgtt tctccattta gcggctgatt acggattgaa agaagcgatg
      121 gaatgttggg agatgacgga ccagtcgact cccctctctt ggcgacttcc caattggctt
      181 ggacgagact tcgaggactt ccctcggctc gccagagttg cgtagtttcg cggtgctgtc
      241 agctgcgtcg ccaacacttt cgaagaaccc acgtaacttg tcgatctcac cccgacggtt
      301 ttctaactcg gactgcagaa atcgtttgtc ggcttccagg ttgacaatcg tctggtcctg
      361 agacgcgatt tgttgttccg ccagatccag ccgatgttgt agaccggaat ccaatccgtc
      421 ttcgattggc tctacagaac tcttgtcttc gctttctttt tccggcgtct gtgtgtcggg
      481 cccgtcccag taccttgatt cgagaaacgc aacttcaacg taccagcgcg gctgcttcgc
      541 ctgcagagtg aggagagcct ctttggttgc ttccttacca ttgagttgag tgccgtcatt
      601 aagcgcgacg cgaaaatgat tcaaaaacga caagtcattt cgatcaaaag cactgtcgat
      661 atcgcgaatg aaagatgctt ttgaacggcg atacgttttt tgcgcgttcg ctctcgtgat
      721 gaatccagga attttggggt gaggcattcg gagtggggga gtggtggcga cagagtgccc
      781 gagtaacgca accgtgtcaa tacggtccca acttcgaagc tgacatcgaa acggtttcaa
      841 agcgttcaat ccgatgaacc gtcgcactac ggtttcaatt cgtcccatgg tgatacggtg
      901 taatctgaat catcaactca atcgctgatt ccgctcgacg atgaagaacc gtcgcgcaac
      961 gggagcagcg gcgttgcagt tgacggtgct tgcacggttg cagtgcggtt tcagaaaacc
     1021 gtttcagact gaagtcgcgc aacggtggcg aaacggactc tggacggttt cgacgtgatc
     1081 aacgtgaatg ccttgcgtcc gcgcaagtgg aattcaggct gcgtttaggc tttggcaaac
     1141 atgactcgca atcactgcgt cgagagccgg agcccagaag tgcattccta cttacaatca
     1201 aattcgaaaa ctgactttga ttgcatttgt gatcatgggc ttttcgggct ccatatgcag
     1261 attgccgtca cccggaaacg gagtaggcgg ccatgacagc gaagaaaccg accgccaatc
     1321 gcaagaggag agtggaagat accgttccag atggggcacc agattgggtc acggaggaat
     1381 tgattcttga aactcttgat acgtggcaac cttactacgg tggttcgttg actgccgaag
     1441 acgcattgga gatactttta ggagtcacga aactctttga gttcatccac gaaatgtagt
     1501 cacccagaat ccttcggagc cggacgatga caaagcgatt tgttgccctc gcccgagtct
     1561 cttcacgtga acaagaacgc gaagggtttt cgctggaagt gcaagaagaa gcactcgaac
     1621 gatacgccga gattcaggac ggcaagatcg tacggttgtt ccgcatcgct gaaacggcga
     1681 ccaagagcga agaacgtcgg tcattcaaga ctttgctcga ttactgcaaa aagaacgcgg
     1741 ccaagctgga tgctttgctg ttcttcaaag tcgaccgtgc cgcacgcaat cttttcgatt
     1801 acgtcgagct tgaacggctg gaagcggact atggcttgcc ggttgaatac atcacccagc
     1861 aaacagaaaa cacgcctgcc ggtcgcatga tgcggcgaac gctggccaat atggccagtt
     1921 tctacacgga gcagcagtcg attgacgtga aagacgggct tcaccgtcgt gtccgaagcg
     1981 ggcttttcgt gggaaaagct ccatacggct acgtcaacgt ccgtcgagag gggagaagcc
     2041 tggttgatat tgatgaagag aaggcgaaac gcgttaggag aatcttcgaa ctgtacgcgt
     2101 tccatggcca cacgctggat tcgctagtcg atcaactcga tgaagagggg attccttaca
     2161 cggcgtcgca acgccgattt gctcgcagca aactgcacaa cattctccga gacagggcct
     2221 acatcggaga gctgaagtac cacgacgaat ggtacccagg cactcaccgt ccgattgtcg
     2281 atcgcggcac gttcgaccgc gtgcaggtct tgatggggga gcaaacctac cagtctcatg
     2341 aattgctgta tgcaggcgag ttgattacgt gcggccattg cggacgaccg attaccggcg
     2401 aggttaagca gaagaagacg aagcgaggaa cgtctactta tcgctactac cgctgcgccc
     2461 ggtacacgaa aggggaccat cctcgaatca gaattcgaga agagaagatt gaagagcagg
     2521 tgctggccat gttcgagcaa ctgaaagtgc aagacgagaa agtgcgacgc tggttcgcca
     2581 acgcgttgcg cgctcgttca aaggatcagc agtcgcaggc gaccgagaag gttgaggact
     2641 tgcaggaaca gattacccgg ttgaacaaac aactcgatca gcttctgaat cttcgcctac
     2701 tcgaagagat cgacgagtcg acttttgcct caaagcaccg cgagctgcga gatcgcatct
     2761 cgtcaatgac gctcaaagtc gaggcgatga atcgttcaaa gtccgaaaaa gcagacgtgg
     2821 cagtgaaagc gtttgaactt tctcaaaccc tttcagagaa atgggttaac gccgatacgc
     2881 gggctaaacg tcaaatcctc gaaatcctct gtttgaactt ttctctggac gacgtaactc
     2941 tagtccctga atggagaaag cccttcgacg tactcgccga agggctcgat tctgaaaata
     3001 gtcgggacga caagatttga acttgcgacc tcttgacccc cagtcaagcg cgctaccagg
     3061 ctgcgctacg tcccgcagtg agggtatgat atcgcgaggg tttggtggct gcaagtcgtt
     3121 ggagttggag gcgtggtggg aaataagtga ttgaggcaaa tcgaatttga tgccagttga
     3181 ttctggggta gtccgttata gacgttggac gatgtctttg aggcgggcga attgttcgac
     3241 gaggcggggg atggtgtcga tgcccatgac gaacatcatc aggtagcgga agacggcgaa
     3301 gatatcgccg gcaagaatgc ctgggatgcg gcaaatcgtc agtagggcaa acgccatcag
     3361 tcccatgacg aagaattctg tcaggccagt cgtgcgggct tccaggtcgg acattttgac
     3421 ccaacaactg gtcatgccgt tgtaatgtgt ggcaacttct tcatcgctag ctttttcgat
     3481 gatttccact tcatcttccc agcgatcatg caatacccgg ctgacacctt tgacactgtg
     3541 actgtaaatg tagttgagca cgaaaacggg cagggcgatg accaggcagg cgatgacgat
     3601 tcgccaatcg taataaaaca gcatcgcaat cgcaccaacg cacgaaaata aggcagagac
     3661 caatttcggg acctgctgtt ccacgaaggt gatgaactga cgcgacaagg ccgcccgggc
     3721 ggcgacgcgg gatgtcggga cttttgcttc tcgttgatag cagacgagat ttgtaactcg
     3781 cttcgcgtac atgtgggaat agacgcgtgt gtcgtacatt tgccgtgcga attgcacaaa
     3841 catgtgactg gcgtgaccgc cgagaaacca ccagaggccg agataggaat tggtcaataa
     3901 tccattgacg gcctgtccta acagaaatgg ttgagccagc ctgagcaaat tctcaaccac
     3961 gagcagcaca taagccagaa tgaccggcca gcgattctga tggatcaatc cgaagagttc
     4021 accaaacacc gttgctttgg gaggtagtcc atcgggaagg atcgcggtcg gggactccat
     4081 gatgtgaatc aatctaagaa ataacaggga ttgcgcagtg atcgcggaaa aagtgatcgt
     4141 gacaataccc gagtcatgac tgactcggct cgcctcaaat actatttaac tgaaggcgat
     4201 caaatggagt tgcgtcaatc ccttagcgaa atctttgagt tcagcaggat caatttcatc
     4261 tgctaatgcc gcccattgag agaaatggca gggtgagaga tcgatgagac gatccaatag
     4321 aatctggcca gccggttcga acatggcggt gcgaacttca tcgtcatcgg cgtagtataa
     4381 ggctgagacc ggcgggctct catcttcatc gaggaacttt ttcgatttca gataggacca
     4441 gctgacagcc gggttgacat gaattgtcaa ttcatcgtta tcacccaatt gttcaagaag
     4501 ttcgactgcg acagtcacca gttcctgaaa gcgaatatgc tttgagcgat tggcacgtgc
     4561 ctgatgttcg acatcgtaac gtgcccgctg acaagcgact gtgtcctgct gctccagtgt
     4621 cagattctga gtttcctcca gccattcgag catcgcatca cactcttcgg tgctgccctc
     4681 gtaagagcga acctgtttcg aatcggcaaa ctgcatcgcc aattcctcga agttttcgaa
     4741 gtcctcatct tcggagacga aaggcatgag cctgatgagc acatcgattc gcttatcgta
     4801 atttccatcg ataaacatct cgacgtgctt ggcttcatac tttttgccga gatagggcag
     4861 gacatcgtca gtacgattct gagcaatcgc gcgggcgact ttctgaatca tatctcgata
     4921 ctgcatctca gcggcttcgg gtgaaagcgg ctttgtttcc tcggtcatat tttcttcggt
     4981 catattcttt tcgggtaagt tcatcctgca ctccctgcga atgcctgtcc ttttgaagag
     5041 gcatcggcga tgtcgtacat cttgtgcaat tcccgacgcc actcctgttc acccgggaat
     5101 tctgcatccc gttcaataaa cacggcatcg actttccctt tgcccagatt caatgagtat
     5161 tcatacaact cccagacatc atcgggaatc ggttgcgaat gcgtatcgaa atagagttgt
     5221 tgttcttcat cccagaagcc acccgccagg tgcatttgca cgcgtgaagc atgcggcatg
     5281 acttcggcga cgaattcttt cgcatcgaat ccgaagttgc gagcgttggc gtagacattg
     5341 gtgacatcga gcaaccagcc acagccggtt cgcttaaaca tctcgatcag aaactccggc
     5401 tcagtcatcg tcccctcgag ctgaaacaga tacgcaatcg tttcaatata aaaaggaaac
     5461 ggagccagga actcctgaac ataattgata tttcggcacg tcacatcgag agcggttgga
     5521 gtgagtggaa caggtgcgaa gtgccccatc tcgacgccat cgtctccatc acgggtgaag
     5581 ccgagatgat cactgattga agtggcgtta ttttcaatcg ccacttgctt caacgtttct
     5641 aggtactcgc gtcccggagg atcgggactg ccgactgaaa gtttcagtgc atggacggct
     5701 acataatcaa tttcgtcccc gccaatgaag ttttttgtcc acagggggag gtcggcatgt
     5761 tcaaatgtaa tttctgcggc gttcagtttc gggtcggtca agatgaaccg attctcacgg
     5821 cgaacggcat atccgatggc gggcatcatg gtggatccct ccttcactcg ttttatgttt
     5881 atgatgaaaa aattgctacc attacattat tgaaatggta gccggaaaaa tgcaaacctg
     5941 ttcacacaat cctgctcaga atgttgattt ctgcactgat ctggcagtca tgaataacaa
     6001 attccatttc gagatgaaga aaatctgcca ctgagcatca aactcgtcgt tgtggttcca
     6061 cttttcagat ctaagtctga aagtgagatg aaccttatat ggtttccgag ttgatgaagt
     6121 cgtgatggca gtgtttcttg tgatttgatt gagcaatgcg ataaacaact cgctcatttt
     6181 tctaagcgaa attcaaatca ctcaggggac acctgagttg ggaatttgta gagattcatt
     6241 gagcgatgaa tgtggcaaac atgttaatgc tgcaaaaagt atcgaaattt ctcagtattt
     6301 caccaattgt aaattggatt acagattctg attaggggtc gtattcgaat aagagcagaa
     6361 taaaatcgaa agaatataga caatgataca attcagagga tctctgagtt gatgtaattc
     6421 ccagttaagg aaaaaatgcc atcgccactt caactcttaa tcattccgaa ttcgcagatg
     6481 atatccgaga tgaattactt cagcgatatt tttcgatacg aaatcaatcg gtcaaactct
     6541 gcgaaggctt actgcctgaa gatctcgtca ttcaatcgat gcccgatgca agtcccttac
     6601 gttggcacct ggcccacacc acgtggttct ttgagacgtt cctgctcaag gaaatcttat
     6661 ccagttacga gccctggaat cctcattttg aagttctgtt caactcctat tacaatagcg
     6721 tgggagagca gtttccgcgt gccaatcgag ggttactcac acggccaagc gtgcaggaga
     6781 ttttcgaata tcgccataaa attgatgaga taattctgca gttgataaag actgaatcac
     6841 ttcatcatga tgctttacga attctggaga tcggactgca gcatgaacag caacatcagg
     6901 aattgatgct gacagacctc aagcatatgt tctcctgcaa cccattgttt ccaatatatc
     6961 gcactcaaaa atcagtgaac cagaattgga attctccaga gcgtaaatgg attgctcacg
     7021 aagaggggct ttatgaaatt ggagccaggc aaagggagtt ctgttatgac aatgaacttc
     7081 ctcgtcatcg tcagtttgta gaatcattct cactctccaa tcgacttgtg acgaacgcag
     7141 agtatctggt gttcatagag gagggaggct atcggcgtcc tgagttctgg ctatccatgg
     7201 gatggcaggc cgtcgagtcg caaaaatgga gttcaccttt gtactggcac cagactgatg
     7261 atggttggtc acagttcaca ttgtccggtt tgcggtcaat tgatggccag gaaccggtta
     7321 cgcatgtcag ttattttgaa gcggatgcct atgctcgctg ggccggatgt cggctaccgg
     7381 aagaagctga atgggagatt gcagctgaag actctgttga caaatatccg gaattgatcg
     7441 ttcaaggaaa ttatgtggag tctgagaaat atcatcctca aatctgctcg aatgaagggg
     7501 caggttcggc ttatcagcag ttgtttggag atgtctggga gtggacgcgc tctcaatatt
     7561 ctgcataccc cggatatcac actcctgaag gagcgattgg ggaatataat gggaagttca
     7621 tgtgcaatca gttcgtgctg cgtggaggtt cctgcgcaac atcagccagt cacattcgta
     7681 gctcttaccg caattttttc ccaccagaga cccgttggca gttttctggc atacggcttg
     7741 caaagtaaat gctaacaaca tatctcgcca gatgattttg aggacatcga tcaatgactg
     7801 attataatac catcacactg caggattctg cggagacaac agaattctat gcggatgtca
     7861 tttcgggctt gaattcaaag ccaaaaacac ttcccagcaa atacttctac gatgaacagg
     7921 gaagcatgct cttcgaccag atttgtgatc tggatgaata ttacatcaca cggaccgaga
     7981 gtcagatcat ggatcgttat gctcatgaca tggcgcggac actcggagag aagattgctc
     8041 tcattgaact gggaagcgga agcagtcgta aaacccgatt gctactcgaa gaagttgctg
     8101 aaagtacggt gtatatgccg gtcgatatct cccgagaaca tctttttaaa tcggctgaac
     8161 aacttgcctt tgatttcccg gatttgtcca tcaaaccaat ccacgccgat ttcacacagc
     8221 cgatcaaact ggataaccag attgaagacg actaccgaaa agttgtgtac tttccaggtt
     8281 ctacaattgg aaatttcgaa cctgaacagg cggttcaatt attgagtaat atttcaaact
     8341 tagtcgatcc agatggaggc ttactcattg ggtatgatct catcaaagat ttgaatattc
     8401 ttgaggatgc ctacaacgat tccgctggtg tcaccgccgc cttcaataag aatttactcc
     8461 atcgaatcaa tcaggaatta gatgggaact tcgatctgga cgcctttgag catcaggcta
     8521 ttttcaatcc ggaagagcat cgcatcgaaa tgcatcttat cagtctgaaa aaacagtcag
     8581 tcaatattgg agaatcaaca tttcattttg aaaaacagga gtcgatctgt accgaatatt
     8641 cgcataaata ttcgatggac agtttccgag aaatggcttt aaaagctggt tttcatgaag
     8701 accgctgctg gaccgatcct aaccagtatt ttgcagtttg caattatcga ctctaatcgc
     8761 attaatcgtc tgtatatttt gaaccacgga tggacaaaga ttttcacgga tatttttatc
     8821 tgtgtttatc cgtgtccatc cgtggttcat ttttatatga ttcaaatatt gattttcata
     8881 acatcaggca agccgattct cattcttaat aagtagtgat tttatgcatc gatttcagct
     8941 cacgaatcaa tttctcctgt cacgaaatat ccttttggtg accttcgcag tcctgattat
     9001 ctcaactgcc ggtcagttca atctgaatgc tgcggaatta ccaaaactca ctaagatgac
     9061 tttccaaagc tcgcttgatg attcgactca acccgcgttg atttggattc cccctaaagc
     9121 gatgcaggag ccaacaccac tatttatctt cctgcattcc tggagtggtg attataagca
     9181 aaataataat gtgtggtttg ctcaggcagt tgccagaaac tggatttatc tgcatcccaa
     9241 ttttcgtggt cgaaacgata acccggcttc ctgcggttca gagttagcac gtcaggatat
     9301 tctcgactgc atccagaagg tgattgactc cactgaagtt gacacttctc ggatttacct
     9361 ggcaggcagt tcgggaggcg gacatatgtc gatgctgatg gcggggtatt accccgatcg
     9421 attctctgcg gtctctgcct gggttggcat cagcgactta gccgagtggt atcggtttca
     9481 ttcccgggga ggaaaacctt ccaactatgc ccgtatggtt caggcgagta ctcagggagt
     9541 tcccggacaa tctcccgaag tcgatgccca atataaggcg agatccccca tctttcatat
     9601 tcaaaatgtg ggtgacttac cactcgactt gaacacagga attcacgatg gtcacactgg
     9661 ctccgttccg attgtgcaca ccatcaatgc cttcaataaa attgctcaag agaagcaggc
     9721 tcctttaatc tcaccagagg aaatcgaaac cttgagtcag gaacaaccat tgagtaaccc
     9781 tcaaccttcc gacattgttc ccaccacaga atatgacacc cgaatctatc tccgtaggca
     9841 tgccggtgaa acaagagtaa cggtatttga aggggggcac gaaagcatac cagtccccgc
     9901 ctgtcgctgg ctctcgaagc aggagagaaa aacggagtgg gtgaaatcca aggaatagga
     9961 atttattgaa agacggaagg atattcatga atacccgtgt ccatccattc catcagtgtg
    10021 aattcggcaa attcaaattc acttcttatt cttctcgctc aaatcaataa aaacatccat
    10081 ctgctgacca acataaatcc gcgagttact attctcgaac tcgtaaatta cctgcagaac
    10141 acgagtatca acgcggtccg cattgtcacc cgttaaagat ctcttaggca caacgtacgg
    10201 ctcaactctg acaaaactca gtggataaga tgttttccca tctccacgag gaaaggcgat
    10261 tgcaggttga ttcggttcaa accgcggcaa atcgtgctca tcgatatcaa cacgaattcg
    10321 tcgctgcccc gcatcggcta aaataacaat cgcctctccg ggaggtgtgc cgacatattc
    10381 accaggccgc ctgttgattt gtaatacctc ccagaccgat ttcgtttcat tattcaccga
    10441 cagaaaaccg gaagttggtg cccgaacttc atgtcgttcc agttctgttt gtgtcttttg
    10501 aatctcagcc cgcatctgtt gtacctggga ttccgtcacc agcaaatcct gctgccaggt
    10561 gccggcaatc actaattgat aatccgcctg agccttctcc agcttcgcct gagcaacttc
    10621 caactgagaa cgagcagtga ctaattcttc atcagtcccg atcttctctc gattcaactt
    10681 ctgttgacgc tcataggcat ccttcgtctg gcgtacttct gcctccgcct ctgtgacatc
    10741 tgcctttgcc ggaggaactt cctcagctcg cggcatccgt tcgagtcgct gatactgagc
    10801 cattacattt tgtaatgagg cttcatgaat tttcagatcg gcttcgaca
//
