LOCUS       c00013_NZ_PPTT..       10870 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_PPTT01000020.1 Eggerthella sinensis strain DSM 16107 NODE_20,
            whole genome shotgun sequence.
ACCESSION   NZ_PPTT01000020
VERSION     NZ_PPTT01000020
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:47:56
            Original ID  :: NZ_PPTT01000020.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 43963
            Orig. end    :: 54833
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10870
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[48963:49833](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5870)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10870
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10870
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             1210..2859
                     /locus_tag="ctg13_38"
                     /transl_table=11
                     /translation="MNALKNGLSRRSFLTLGGVAALGGAAALAGCAPKASAPDAKAEAA
                     DDATTMQTADQTKECDIAIVGAGGAGLWAAVEAVRAGKSVVVIEKGGNVGVANGSLAGG
                     PFMVGSKLQEEAGIDFTVEEAFNHIMEYAHWSTNAAAVKAAVAISGETVDQFTDDFGVP
                     TGMRPDNYGAGHASVRANFQSDPSDSKTQTKGEDRMKPLQEFVESKGGTFLFNTAGKRL
                     IMEDGVCTGVQCEGDGVIDVKAKAVIVATGGFMGNVDMMREKFGTFVNPLGNILSVGEG
                     IDMVQAAGGQVSTQWGIAGNEFTGSNQKADGLYDRKSAAFTIGIYGTLLVNNQGRRFSN
                     EGKFANLPLALGGAISLVGGKYYAVVDQAYVDGLNSGMDAWTLCGSDEEHWHTGMMTLK
                     GKALENVQGSIDDAVSAGWAFKADSIEALAEAIDAPELVNTLDEYNGYCADGKDEQFYK
                     PACFLQPVTTGPFYAFQYEPSAWVTIGGIRTNDRLQAIDGDGLPIAGLYVAGADNGTLM
                     SAPYCDYEGYSLMCAYCGGRLAGQYAAETLDA"
     PFAM_domain     1390..2760
                     /aSDomain="FAD_binding_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00890.26"
                     /description="FAD binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_38_0001"
                     /evalue="5.00E-47"
                     /label="ctg13_38"
                     /locus_tag="ctg13_38"
                     /protein_end="517"
                     /protein_start="60"
                     /score="161.0"
                     /tool="antismash"
                     /translation="DIAIVGAGGAGLWAAVEAVRAGKSVVVIEKGGNVGVANGSLAGGP
                     FMVGSKLQEEAGIDFTVEEAFNHIMEYAHWSTNAAAVKAAVAISGETVDQFTDDFGVPT
                     GMRPDNYGAGHASVRANFQSDPSDSKTQTKGEDRMKPLQEFVESKGGTFLFNTAGKRLI
                     MEDGVCTGVQCEGDGVIDVKAKAVIVATGGFMGNVDMMREKFGTFVNPLGNILSVGEGI
                     DMVQAAGGQVSTQWGIAGNEFTGSNQKADGLYDRKSAAFTIGIYGTLLVNNQGRRFSNE
                     GKFANLPLALGGAISLVGGKYYAVVDQAYVDGLNSGMDAWTLCGSDEEHWHTGMMTLKG
                     KALENVQGSIDDAVSAGWAFKADSIEALAEAIDAPELVNTLDEYNGYCADGKDEQFYKP
                     ACFLQPVTTGPFYAFQYEPSAWVTIGGIRTNDRLQAIDGDGLPIAGLYVAGADNGTLM"
     CDS             3116..4834
                     /locus_tag="ctg13_39"
                     /transl_table=11
                     /translation="MPTLKEVAQVAVEARREKGSGSGKRLREIERILRRHRVWSGLTPE
                     QATSLLEDLGPTFVKMGQIAANRSDVIPPAYADAFKRLRADVPPMPFSTVIETIESSLG
                     HPWQETFSCIEEKPLGSASIAQVHKACIAAHAVGDARGGATAEALPSTAPDAGTWVAVK
                     VRRPNVVEQMTQDLALIRQTVALVGLTRATDGIKLNLDDLVSELERTTHQELDFCIEQE
                     NLVRFRQFLSDQSGVESPRPYPRMSSDDVLVMDFIAGPMINDVPALRAQGLDPAKLGQR
                     LAESYVTQIVDNGFFHADPHPGNILVHDGDIVWIDLGMVGELSALERALIGRMFRAVAE
                     NDPYALMEALLGAARVEGPVDHGRLLSQLGNLLVSYTTVNLADINVGSALVDVFGVLRS
                     QNLALPSSFTLLARGMVTIEGVLVDIAPNTSVIDIISDHVKRRTRTWAALETKAREFAS
                     SALTSAESAVRLPTQASHTLDMIDRGQIRVGADLGIPTDAIAALYSVSGTVAMALISAG
                     LFVGSSLLATTNMHPQFLGVPLLGVLGYLGAFALGAYVVWRNIVIRHRQKNEEKL"
     PFAM_domain     3362..4159
                     /aSDomain="ABC1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03109.18"
                     /description="ABC1 atypical kinase-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_39_0002"
                     /evalue="4.50E-57"
                     /label="ctg13_39"
                     /locus_tag="ctg13_39"
                     /protein_end="348"
                     /protein_start="82"
                     /score="193.0"
                     /tool="antismash"
                     /translation="LRADVPPMPFSTVIETIESSLGHPWQETFSCIEEKPLGSASIAQV
                     HKACIAAHAVGDARGGATAEALPSTAPDAGTWVAVKVRRPNVVEQMTQDLALIRQTVAL
                     VGLTRATDGIKLNLDDLVSELERTTHQELDFCIEQENLVRFRQFLSDQSGVESPRPYPR
                     MSSDDVLVMDFIAGPMINDVPALRAQGLDPAKLGQRLAESYVTQIVDNGFFHADPHPGN
                     ILVHDGDIVWIDLGMVGELSALERALIGRMFRAVAENDPYALME"
     CDS             complement(5001..5870)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Linocin_M18"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_40"
                     /sec_met_domain="Linocin_M18 (E-value: 1.9e-80, bitscore:
                     261.6, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFHVKHSFASAYSPRKESAMDYLARESADLSDGLWNRIDSTVIGT
                     ARNQLTCRRFLKVFGPLGPGVTSVAVDGVNKEEVLEDGIGRIVGRTQLELPMFFEDFTL
                     LGRDMEYAAQTGYPLDLSVAIAAAKKASRREDDLILNGNKALGADGLLTVKGSTKIKKG
                     DWAQGENSFADVTAGVAQLAKTGYLGRYALVVSPDLFLDLQRLQPNTGLLEIDRIKKLI
                     GDNVYMTSVMGPGKAVLVCAEPEYLDLAVGLDLSVGYLELADFNHTFRIMETAALRVKD
                     PAAIVVFA"
     PFAM_domain     complement(5046..5813)
                     /aSDomain="Linocin_M18"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04454.14"
                     /description="Encapsulating protein for peroxidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_40_0003"
                     /evalue="3.50E-77"
                     /label="ctg13_40"
                     /locus_tag="ctg13_40"
                     /protein_end="275"
                     /protein_start="19"
                     /score="259.2"
                     /tool="antismash"
                     /translation="MDYLARESADLSDGLWNRIDSTVIGTARNQLTCRRFLKVFGPLGP
                     GVTSVAVDGVNKEEVLEDGIGRIVGRTQLELPMFFEDFTLLGRDMEYAAQTGYPLDLSV
                     AIAAAKKASRREDDLILNGNKALGADGLLTVKGSTKIKKGDWAQGENSFADVTAGVAQL
                     AKTGYLGRYALVVSPDLFLDLQRLQPNTGLLEIDRIKKLIGDNVYMTSVMGPGKAVLVC
                     AEPEYLDLAVGLDLSVGYLELADFNHTFRIMETA"
     CDS             complement(5918..6289)
                     /locus_tag="ctg13_41"
                     /transl_table=11
                     /translation="MPSFPNPFAGNVDRKMTNAELMQALRIDIAGELEAIFLYDAHYQA
                     TDDPAAKAVLADIRDEEKAHMGELITLMRHLDPTETEFFLEGEGEVQEKLAELGIKTDG
                     EIAPAPAEPAPAPTVGDLS"
     PFAM_domain     complement(6065..6226)
                     /aSDomain="COQ7"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03232.15"
                     /description="Ubiquinone biosynthesis protein COQ7"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_41_0004"
                     /evalue="1.90E-06"
                     /label="ctg13_41"
                     /locus_tag="ctg13_41"
                     /protein_end="75"
                     /protein_start="21"
                     /score="27.8"
                     /tool="antismash"
                     /translation="MQALRIDIAGELEAIFLYDAHYQATDDPAAKAVLADIRDEEKAHM
                     GELITLMRH"
     CDS             complement(6386..7096)
                     /locus_tag="ctg13_42"
                     /transl_table=11
                     /translation="MEDARKTLIKKRIAVIVGLLALTAGLAAFCILYGPELLAFVADAP
                     RFRAWVDETGPLSRVVFVLANMAQIVFAFLPGEPLELGAGYAFGFWEGTLWCLVASALG
                     TAAVMLLVRTFGMRIVGLFFSPEKITSMKWLQDSRRFELLLFLCFLIPGTPKDLLTYVA
                     GLGTSSVGRIVALTTVGRIPSVITSTLAAGAFGDGNYLGAAAIAVLTLALAGIGVVAYR
                     KLAFKSVVIENSYQ"
     PFAM_domain     complement(6533..6874)
                     /aSDomain="SNARE_assoc"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09335.13"
                     /description="SNARE associated Golgi protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_42_0005"
                     /evalue="1.00E-13"
                     /label="ctg13_42"
                     /locus_tag="ctg13_42"
                     /protein_end="188"
                     /protein_start="74"
                     /score="51.8"
                     /tool="antismash"
                     /translation="LPGEPLELGAGYAFGFWEGTLWCLVASALGTAAVMLLVRTFGMRI
                     VGLFFSPEKITSMKWLQDSRRFELLLFLCFLIPGTPKDLLTYVAGLGTSSVGRIVALTT
                     VGRIPSVITS"
     CDS             complement(7154..8845)
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 97; E-value: 2.4e-29)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg13_43"
                     /transl_table=11
                     /translation="MARVAGSPDGGRAPHPDERPSVFARIRHSWRNASLKTSFMVYMLV
                     FLLIALVVSSATASVFASLQNDATRDAYEMSGLYLYDESTDSLVPARAVEIDENGSSVF
                     VQTVRDDMTSLPMRDVSPLTSITDASDYQYTSVTFGLSGSQSSDETSDALTIEAPEDED
                     LPAEDLSVEGLPVYDAQARARFYAWIEEHPESPYAAFFSADDDPAFDNGSSSGLLTSPI
                     GYYLSTPPSDEALLLSSLFGTLTFLMFPLWFGLCIFAAARRFFQKRLQPGFTVLDEAAS
                     NIAHQDLDFVVAYDRDDELGRLASSFETMRASLAASQRSLWRTAEERKRLNAAFAHDLR
                     TPLTILKGKIELLDAHLQTGDASPERLAASVSSLADQVKRLERYVEAMSGLQKLEDRTI
                     TAHDVPFDDAAIMIDDIGVALSAQHGRAFGLSVSPRCDRERPALRLDQSIVGEVAENLL
                     SNAARYACARIDARMDVQDGSLVLIVEDDGPGFSPDALERGCAPFFSEAPSSDHFGLGL
                     NIASLLCEKHGGGLVLENREPSGTEGGGGARVIARFSLECGDVDSR"
     PFAM_domain     complement(7193..7498)
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_43_0008"
                     /evalue="1.20E-10"
                     /label="ctg13_43"
                     /locus_tag="ctg13_43"
                     /protein_end="551"
                     /protein_start="449"
                     /score="42.0"
                     /tool="antismash"
                     /translation="VGEVAENLLSNAARYACARIDARMDVQDGSLVLIVEDDGPGFSPD
                     ALERGCAPFFSEAPSSDHFGLGLNIASLLCEKHGGGLVLENREPSGTEGGGGARVIA"
     PFAM_domain     complement(7661..7864)
                     /aSDomain="HisKA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00512.27"
                     /description="His Kinase A (phospho-acceptor) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_43_0007"
                     /evalue="6.50E-10"
                     /label="ctg13_43"
                     /locus_tag="ctg13_43"
                     /protein_end="395"
                     /protein_start="327"
                     /score="39.0"
                     /tool="antismash"
                     /translation="RKRLNAAFAHDLRTPLTILKGKIELLDAHLQTGDASPERLAASVS
                     SLADQVKRLERYVEAMSGLQKLE"
     PFAM_domain     complement(7904..8014)
                     /aSDomain="HAMP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00672.27"
                     /description="HAMP domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_43_0006"
                     /evalue="2.40E-05"
                     /label="ctg13_43"
                     /locus_tag="ctg13_43"
                     /protein_end="314"
                     /protein_start="277"
                     /score="24.7"
                     /tool="antismash"
                     /translation="EAASNIAHQDLDFVVAYDRDDELGRLASSFETMRASL"
     CDS             complement(8833..9576)
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 200.4; E-value: 4.7e-61)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg13_44"
                     /transl_table=11
                     /translation="MVDFRRSMQHTEGSTVGETERASHTTILVVDDEAEIVALLDEYFT
                     GLGYEVLTAGDGAAALKRAEQNPDLIVLDVGMPLMDGYTVCRRLREHLTCPIIFLTARV
                     EDVDALEGFEAGADDYVLKPFSLAVLGARVKAHLARTNRQQTKTEVRFDGDIVIDYRTR
                     IVTVAGQPVDLTRREFDIVAFLSKHPGQVFERERIHERVGGWENESDPQVVTEHIRRIR
                     KKLATAGAAPDPVETVWGMGYRWRA"
     PFAM_domain     complement(8845..9072)
                     /aSDomain="Trans_reg_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00486.30"
                     /description="Transcriptional regulatory protein, C
                     terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_44_0010"
                     /evalue="2.00E-22"
                     /label="ctg13_44"
                     /locus_tag="ctg13_44"
                     /protein_end="244"
                     /protein_start="168"
                     /score="79.2"
                     /tool="antismash"
                     /translation="GQPVDLTRREFDIVAFLSKHPGQVFERERIHERVGGWENESDPQV
                     VTEHIRRIRKKLATAGAAPDPVETVWGMGYR"
     PFAM_domain     complement(9175..9498)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_44_0009"
                     /evalue="6.00E-27"
                     /label="ctg13_44"
                     /locus_tag="ctg13_44"
                     /protein_end="134"
                     /protein_start="26"
                     /score="94.1"
                     /tool="antismash"
                     /translation="ILVVDDEAEIVALLDEYFTGLGYEVLTAGDGAAALKRAEQNPDLI
                     VLDVGMPLMDGYTVCRRLREHLTCPIIFLTARVEDVDALEGFEAGADDYVLKPFSLAVL
                     GARV"
     CDS             complement(9614..10099)
                     /locus_tag="ctg13_45"
                     /transl_table=11
                     /translation="MLYDNIMVPYDGSPSAQAALAEAVRFAKDDPGLTLRIVHIIDTEQ
                     LAIDKLEAEGRDEQIVSTSGTLQATFAAVTAEAEERLRRRIDPLLKGLMNKVHVELLQE
                     TSPGDQIVTYAVDNGCDLIVMGSRGLGALRGMLGSVSSFVLRNADVPVLIVKEGTNE"
     PFAM_domain     complement(9632..10093)
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00582.28"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg13_45_0011"
                     /evalue="3.70E-28"
                     /label="ctg13_45"
                     /locus_tag="ctg13_45"
                     /protein_end="156"
                     /protein_start="2"
                     /score="98.9"
                     /tool="antismash"
                     /translation="YDNIMVPYDGSPSAQAALAEAVRFAKDDPGLTLRIVHIIDTEQLA
                     IDKLEAEGRDEQIVSTSGTLQATFAAVTAEAEERLRRRIDPLLKGLMNKVHVELLQETS
                     PGDQIVTYAVDNGCDLIVMGSRGLGALRGMLGSVSSFVLRNADVPVLIVK"
ORIGIN
        1 aacaggcgca agctggggac ctcgaatcga aacgagatgt tagccagcat gagcagcacg
       61 aagaacgtga accacacgta cgccaatttc agcaggaacg acacggcgta gctccacgtt
      121 cctgcggcga aggggatgag ggcgattgcc acgatggcca gcggcagggc tgctttcgcc
      181 aagaagcgca cgtcaacgcg gttcttcagc gtgaacgccg cgagtatgat ggcgacgccc
      241 gcgagcccgg tagcggccac gcggtgcacc gatccggttc cgtcgggatt cgtcagcagc
      301 gatcccgcca ggcccgagat gaatcccgcc accgccatga tggcgatgag cttccaggga
      361 agcgggtagt gcacgttgtg caggcgcgcc ggttcgcttg gcaggatgcg gaagctgagc
      421 atggcgcatc cgagcgacgc aaggggcagc agcgaggtgg cgatgacggc gaacggtgcg
      481 ctcatggtgt acaccatgaa ggatgcgacg gccgccgcga tgcaggagaa cgcgccgtac
      541 atgagggttc gcgtagctcc catctggctg tacgcttcgg cccagagaca gaagagcacg
      601 gcgccgcccc atgcggtcgc gacggaggcg acgatgacaa ccccttcggg agcgttcatc
      661 ggaatgagga cgaggcccac gacggcggtt ccgacggtgg tggccgcgac cagcgcgacg
      721 cagagcgctc ggcgattgct gagacgccct atgcgcgatg cgaacagcgc caacaccgcg
      781 aacatgccga tatcgccgaa gcgcatgccg gtgtcgaagg cgttgcgcaa gccgaggtcg
      841 aggtcgggtc ccggaaagac gtgggggata tgcgtgcagc agagccaggc gatgaacagc
      901 cccatcccca agaagcgcag ggggtacagc agggcggaga ggggctcgtc gtcgccggct
      961 tggtcggccg gggccaacgc gcgcaccaca tcgctcgatt tcatcgacgc ctccttcgct
     1021 ctcttccgcc cgttcgtcgt gccattgtac caggggtgaa tgcaggggtg aatgcgagtt
     1081 cacccctcgg ccgggcagtt cacccgcgac aaggtgcctg atccggggca tgcttgcctc
     1141 agcgcctcgg gagggcgcgg caccgggcct tcggggcggg tgcatcgtag atctctagga
     1201 gggattcaca tgaacgcact gaagaacgga ctttctcgtc ggagcttcct gacgctgggc
     1261 ggcgtcgcgg cactgggcgg cgcggcggcg ctcgccggat gcgcgccgaa ggcttccgcg
     1321 cccgatgcga aagccgaggc ggccgacgac gcgacgacca tgcagacggc cgaccagacc
     1381 aaggaatgcg acatcgccat cgtgggcgcc ggcggcgcgg gcctgtgggc cgcggtcgag
     1441 gccgtgcgtg cgggcaagag cgtcgtggtc atcgagaagg gcggcaacgt gggcgtggcg
     1501 aacggttcgt tggctggcgg cccgttcatg gtgggctcga agctgcagga ggaagccggc
     1561 atcgacttca cggtggagga agctttcaac catattatgg agtacgcgca ctggtccacg
     1621 aacgcggcgg cggtgaaggc ggcggtggct atctccggcg agacggtgga ccagttcacc
     1681 gacgacttcg gcgtgccgac gggcatgcgc cccgacaact acggcgccgg ccatgcgtcc
     1741 gtgcgtgcga acttccagtc cgacccgagc gattccaaga cccaaaccaa gggcgaggac
     1801 cgcatgaagc cgctgcagga gttcgtggag agcaagggcg gcacgttcct gttcaacacg
     1861 gccggcaagc gcctcatcat ggaggacggc gtgtgcacgg gcgtgcagtg cgaaggcgac
     1921 ggcgtgatcg acgtgaaggc gaaggccgtc atcgtggcga cgggcggctt catgggcaac
     1981 gtcgatatga tgcgcgagaa gttcggcacg ttcgtgaacc cgctgggcaa catcctgtcc
     2041 gtgggcgagg gcatcgacat ggtgcaggcc gcgggcggtc aggtgtccac gcagtggggc
     2101 atcgccggca acgagttcac cgggtcgaac cagaaggccg acggcctgta cgatcgcaag
     2161 agcgccgcat tcaccatcgg catctacggc acgctgctcg tgaacaacca ggggcgccgc
     2221 ttctcgaacg agggcaagtt cgcgaacctg ccgctggcgc tgggcggggc catctcgctt
     2281 gtgggcggca aatactacgc ggtggtggat caggcgtacg tcgacggctt gaattccggc
     2341 atggatgcgt ggacgctgtg cggctccgac gaggagcatt ggcacaccgg catgatgacg
     2401 ctcaagggca aggcgcttga gaacgtgcag ggcagcatcg acgacgcggt gagtgccggg
     2461 tgggccttca aggccgacag tatcgaggcg ctggccgagg ccatcgacgc tcccgagctg
     2521 gtgaacacgc ttgacgagta caacggctac tgcgccgacg gcaaggacga gcagttctac
     2581 aagccggctt gcttcctgca gccggtgacc accggtccgt tctatgcgtt ccagtacgag
     2641 cccagcgcgt gggtgaccat cggcggcatt cgcacgaacg accgcctgca ggccatcgac
     2701 ggcgacgggc tgcccatcgc cgggctgtac gtagccggtg ccgacaacgg cacgctcatg
     2761 agcgctcctt actgcgacta cgagggctac tcgctcatgt gcgcctactg cggcggccgt
     2821 ctggccggtc agtacgctgc cgaaaccctc gacgcgtaag gtcgcgccgc agcagcatcg
     2881 ccaaccaacc cgcaggggcg cacgcgcatc tccctccctc cgcgtcgcgc cccgttttcg
     2941 ccgcccccgc ctgcgcagac gggggcggcc ttgttgcgcg cgcctccctg gggcgctttg
     3001 tccttcggtt cgtcttcctc tgggtgaccg ctttgcgaca gaacgtgctg cgcgggcgcg
     3061 ccatgctacg ctgggatgtc ggatgacgat gaccggacgg gtgaggaggt gcggcatgcc
     3121 cacgctcaag gaagtggcgc aggtggccgt ggaggcgcgg cgcgagaagg gctcgggctc
     3181 gggcaagcgc ctgcgcgaaa tcgagcggat tctgcggcgg caccgcgtgt ggtcgggcct
     3241 cacgcccgag caggccacga gcttgctcga ggacctcggc cccacgttcg tgaagatggg
     3301 ccagattgcc gcgaaccgca gcgacgtgat tcctcccgcg tacgccgacg cgttcaagcg
     3361 gttgcgtgcc gacgtgccgc ccatgccgtt ttccacggtg atcgaaacca tcgagtcgtc
     3421 gctcggccat ccgtggcagg agacgttctc gtgcatcgag gagaagccgc tcggctcggc
     3481 gtccatcgcg caggtgcaca aggcgtgcat cgccgcgcat gccgtgggcg acgcgcgcgg
     3541 cggcgcgacc gccgaggcgc tgccttccac ggcgccggat gcgggcacgt gggtggccgt
     3601 caaggtgcgc cgcccgaacg tggtggagca gatgacgcag gacctcgcgc tcattcgcca
     3661 gaccgttgcg cttgtggggc tgacgcgcgc gaccgacggc atcaagctga atctcgacga
     3721 cctcgtgagc gagctcgagc gcacgaccca ccaggagctg gacttctgca tcgagcagga
     3781 gaacctcgtg cgcttccggc agttcttgag cgaccagtcc ggcgtggaaa gcccgcgtcc
     3841 ctacccgcgc atgagctccg acgacgtgtt ggtgatggac ttcatcgccg gccccatgat
     3901 caacgacgtg cccgcgctgc gcgcgcaagg tctcgacccg gcgaagctgg gtcagcgcct
     3961 ggccgagagc tacgtcacgc aaatcgtgga caacggcttc ttccacgccg acccgcaccc
     4021 cggcaacatc ctcgtgcacg acggcgacat cgtgtggatc gacctcggca tggtgggcga
     4081 gctgtcggcg ctcgagcgcg cgctcatcgg ccgcatgttt cgcgccgtgg ccgagaacga
     4141 cccctatgcg ctcatggagg cgctgctggg tgccgcacgc gtggaaggcc ccgtcgatca
     4201 cgggcgcctg ctcagtcagc tgggcaacct gctggtgtcg tacaccacgg tgaacctggc
     4261 cgacatcaac gtgggctcgg cgctggtgga tgtgttcggc gtgctgcgat cgcagaacct
     4321 ggccctgccg tcctcgttca cgctgctcgc gcgcggcatg gtgaccatcg agggcgtgct
     4381 ggtggacatc gcgccgaata cgagcgtcat cgacatcatc tccgaccacg tgaaacgccg
     4441 cacccgcacc tgggcggcgc tcgaaacgaa ggcgcgcgag ttcgcctcga gcgcgctgac
     4501 gtccgccgag tccgccgtgc gcctgcccac gcaggcgtcg cacacgctcg acatgatcga
     4561 ccgcggccag attcgcgtgg gcgccgacct gggcattccc accgatgcca tcgccgcgct
     4621 ctattccgtc agcggtaccg tggccatggc cctcatctcc gccggcctgt tcgtgggctc
     4681 gagcctgctg gccaccacga acatgcatcc ccaattcctc ggcgtccccc tgctcggcgt
     4741 cctcggctac ctgggcgcct tcgccctcgg agcctacgtc gtatggcgca acatcgtcat
     4801 ccgccatagg caaaagaacg aggagaagct gtaagcctgc gcgcgggctg cgctcaagtt
     4861 catgctgagc ggccacggcc atgacgttcg gtcgcttggc gggtacgaac gctgctgcgg
     4921 ggctttaggg catgaaaaaa gggagccggc ttggggccgg ctcccgatgc gtgcgggtgg
     4981 tgcgggattg tgcgtgctcg ctaggcgaac acgacgatgg cggcggggtc cttgacgcgc
     5041 agggcggccg tctccatgat gcggaacgtg tggttgaagt ccgcgagctc caggtagccc
     5101 accgagaggt cgaggccgac ggcgaggtcg aggtactcgg gctcggcgca cacgagcacg
     5161 gccttgccgg ggcccatgac gctggtcatg tacacgttgt cgccgatgag cttcttgatg
     5221 cggtcgattt ccagcaggcc ggtgttcggc tgcagacgct gcaggtcgag gaacaggtcg
     5281 ggcgacacca caagcgcgta gcggccgagg tagccggtct tggcaagctg cgcaacgccg
     5341 gcggtgacgt cggcgaagct gttctcgccc tgagcccagt cgcccttctt gatcttcgtc
     5401 gagcccttca cggtgagcag gccgtcggcg ccgagcgcct tgttgccatt caggatgagg
     5461 tcgtcctcgc ggcgcgacgc cttcttcgcg gcggcgatgg ccaccgagag atcaagcggg
     5521 tagccggttt gcgcggcgta ctccatgtcg cggccgagga gggtgaagtc ctcgaagaac
     5581 atcggcagct cgagctgcgt gcgtccgacg atgcggccga tgccgtcctc aagcacctct
     5641 tccttgttca cgccgtcgac ggcaaccgag gtcacgccgg ggccgagcgg gccgaacacc
     5701 ttgaggaagc ggcggcacgt cagctggttg cgcgccgtgc cgatgacggt gctgtcaatg
     5761 cggttccaca ggccgtccga aaggtcggcc gattcacgag cgagataatc catagcggac
     5821 tcctttcgag gagaatacgc ggatgcgaac gaatgtttca cgtgaaacat tcggcctcca
     5881 tcagcggaaa aggcagaaaa gcgaaaaacg aaacaggtta cgacaggtcg cctacggtgg
     5941 gggcgggagc gggctcggcc ggggccgggg caatctcgcc gtcggtcttg atgccaagtt
     6001 cggcaagctt ctcctgcacc tcgccttcgc cctccaggaa gaactccgtc tccgtggggt
     6061 cgaggtggcg catcagcgtg atgagctcgc ccatgtgagc cttctcctcg tcgcggatgt
     6121 cggcgagcac ggccttcgcg gccggatcgt cggtggcctg atagtgggcg tcgtacagga
     6181 agatggcttc aagctcgcca gcgatatcga tgcggagcgc ctgcatgagc tcggcgttcg
     6241 tcatcttgcg atcgacgttg ccggcaaacg ggttggggaa actgggcatg agatccctct
     6301 ctttcggtgt gaacagcggt tcttttcatc tctctgttcg atatgatact ccgtttgtca
     6361 tgatagaaac ataacgagtt ggtcattatt gataactatt ctcaataact acagacttga
     6421 aggcgagctt gcgatacgcc accacgccga tgcccgcaag cgccagggtg agcacggcga
     6481 tggccgcggc tcccaggtag ttcccgtcgc cgaatgcgcc ggcggccagc gtcgaggtga
     6541 tgacggaggg gatgcgcccg acggtggtga gggccacgat gcgcccgacg gagctcgtac
     6601 ccagcccagc tacgtaggtg agcaggtctt tcggcgtgcc cggaatgagg aagcacagga
     6661 acaggagcag ctcgaagcgc cgcgaatcct gcaaccactt catggacgtg atcttctcgg
     6721 gcgagaagaa cagccccacg atgcgcatgc cgaacgtgcg cacgagcagc atgaccgccg
     6781 ccgtgccgag tgcgctcgcg acgaggcacc acagcgtgcc ctcccagaag ccgaacgcgt
     6841 acccggctcc cagctcgagc ggttcgcccg gcaggaaggc gaacacgatt tgcgccatgt
     6901 tggccagcac gaacaccacg cggctgagcg ggcccgtctc gtcgacccat gcgcggaagc
     6961 gcggggcgtc ggccacgaac gcgagcagct cgggtccgta caggatacag aacgcggcca
     7021 accccgcggt gagcgcaagc aggccgacga tgacggcgat gcgcttcttg atgagggtct
     7081 tccgtgcgtc ttccatgggg gctccgtttt ctcgggggcg ttcggtacgc ttccgatgct
     7141 acggggcaaa tatctaccgg ctgtctacgt cgccgcattc gagcgaaaat cgggcgatca
     7201 cccgcgcgcc gcccccgcct tccgtgccgc tcggctcgcg attttccagc acgagcccgc
     7261 cgccgtgctt ctcgcacagc agcgacgcga tgttcaatcc caggccgaaa tggtcgctcg
     7321 acggagcctc gctgaagaag ggcgcgcacc cgcgttcgag cgcgtcgggc gaaaagccgg
     7381 gcccgtcgtc ttccactatc agcacgaggc tgccatcctg cacgtccatg cgcgcgtcga
     7441 tgcgggcgca ggcgtaacgg gcggcgttgc tcagcaggtt ctcggcaacc tcgcccacga
     7501 tggattggtc gaggcggagg gcggggcgct cgcgatcgca gcgcgggctg acggacagcc
     7561 cgaacgcgcg cccgtgttgc gcgctcaacg ccacgccgat gtcgtctatc atgatggctg
     7621 cgtcgtcgaa cggcacgtcg tgtgcggtga tggtgcgatc ttcgagcttt tgcaggccgc
     7681 tcatggcttc gacgtaacgc tcaaggcgtt tcacctgatc ggccaaggac gacaccgacg
     7741 cggcaaggcg ctcgggcgag gcgtcgcccg tctgcaggtg cgcgtcgagc agctcgatct
     7801 tccccttgag gatggtgagc ggcgtgcgca ggtcgtgcgc gaatgccgcg ttgaggcgct
     7861 tgcgctcttc ggcggtgcgc cacagcgagc gctgcgacgc agccagcgat gcgcgcatgg
     7921 tttcgaacga cgatgccagg cggcccagct cgtcgtcgcg gtcgtacgcc acgacgaagt
     7981 cgagatcctg atgcgcgatg ttcgaggccg cttcatcgag cacggtgaag cccggttgca
     8041 ggcgcttctg gaagaagcgc cgcgccgccg cgaagatgca caggccgaac cacagcggga
     8101 acatgaggaa cgtgagcgtg ccgaacaggc tggacaggag cagcgcctcg tcggaaggcg
     8161 gcgtggacag gtaatagcct atcggcgatg tgagcaggcc ggatgagctt ccgttgtcga
     8221 aagcggggtc gtcgtcggcc gagaagaacg cagcataggg gctttcggga tgctcctcga
     8281 tccaggcgta gaatcgggca cgcgcctgcg cgtcgtagac gggcaaccct tcgacggaca
     8341 ggtcttcggc gggtaggtct tcgtcttccg gggcttcgat ggtgagcgcg tcggaggttt
     8401 cgtcgctcga ctgagagccg ctcaggccga acgtgacgct ggtgtattgg tagtcgctcg
     8461 cgtcggtaat gctggtgagc ggcgacacgt cgcgcatggg cagtgaggtc atgtcgtcgc
     8521 gcaccgtctg tacgaacacg ctgctgccgt tctcatcgat ttccacggcg cgcgccggca
     8581 cgagggaatc ggtgctctcg tcgtacaggt agaggccgga catttcgtag gcgtcgcggg
     8641 tggcgtcgtt ttgcagcgag gcgaataccg aggccgtggc gcttgaaact acgagcgcga
     8701 tcagcagaaa caccagcata tacaccatga acgacgtctt gagcgacgcg ttgcgccagc
     8761 tgtgccggat gcgggcgaac acgctcgggc gctcgtcggg gtgcggggcg cgccctccgt
     8821 cgggcgatcc cgctacgcgc gccatcggta ccccatgccc cacaccgttt ccactgggtc
     8881 gggtgccgcg cccgccgttg ccagcttctt gcggatgcgg cggatgtgct cggtcaccac
     8941 ctgcgggtcg ctttcgtttt cccatccgcc cacgcgctcg tggatgcgct cgcgctcgaa
     9001 cacctgtccg ggatgcttcg acaggaaggc gacgatgtcg aactcgcgcc gcgtcaggtc
     9061 cacgggttgc ccggccaccg taacgatgcg cgtgcgatag tcgatgacga tatcgccgtc
     9121 gaaccgcacc tcggtcttgg tttgctggcg gttcgtgcgc gcaagatgcg ccttcacgcg
     9181 cgcgccgagc acggcgagcg aaaacggttt gagcacgtag tcgtcggcgc cggcctcgaa
     9241 gccctcgagc gcgtcgacgt cttctacgcg cgccgtgagg aagatgatgg ggcaggtgag
     9301 gtgctcgcgc aggcggcggc ataccgtata gccgtccatg agcggcatgc ccacgtcaag
     9361 cacgatgagg tcgggattct gctcggcgcg cttgagcgcg gccgcgccgt cgccggcggt
     9421 gagcacctcg tagcccaaac ccgtgaaata ctcgtcaagc agcgcaacga tttccgcctc
     9481 gtcgtccacg acgaggatgg tggtgtgcga tgcgcgctcg gtttctccca cggtgctccc
     9541 ttcggtgtgc tgcatgctgc gccggaagtc taccatgaga atgtcaagaa acggtcaacg
     9601 cgcgcgccgc gtttcactcg ttggtgcctt ccttcacgat gagcacgggg acgtcggcgt
     9661 tgcgcagcac gaagctgctc acgctaccca gcatgccgcg gagggcgccc aggccgcgcg
     9721 agcccatgac gatgaggtcg cagccgttgt cgacggcgta cgtcacaatt tgatcgccgg
     9781 ggctggtttc ttgcagcagc tccacgtgca ccttgttcat caggcccttg agcagggggt
     9841 cgatgcggcg gcgcaggcgc tcttccgctt cggcggtgac ggctgcgaac gtggcttgga
     9901 gcgttcccga ggtggacacg atctgctcgt cgcgcccttc ggcttccagc ttgtcgatgg
     9961 caagctgctc ggtgtcgatg atgtggacga tgcgcagcgt gaggccgggg tcgtctttgg
    10021 cgaagcgcac cgcttccgca agcgccgcct gagccgaggg cgaaccgtcg tagggaacca
    10081 tgatgttgtc gtaaagcatg gcaactcctt ttcgcacgcg aggtggaacg ttgccatcag
    10141 tatagcagcc cggcgcgcgc ggggttttcg ctgcggcatc ttggtttcag agcgtgaagt
    10201 aatacgattc cagcaggtag gactgctcgt agcgctcggc aagcagcagg aggcggcgct
    10261 tgacggcctc gccggttgcc tcgccgcgcc cgaagcgcgt catgagcgtg tcgaacgagg
    10321 tgcgctcgcg cgtggtgacg tgcggggaca cgtagcccca cacgtgctgc gccgcgttgc
    10381 ggaacgagcc ggggtcttcg ggcagggaca gcgcgcgttc ggcggtttcg tagaacggca
    10441 cggcggggta gccgtgcttg tctttgagca gttggcgaag ggcctggtag gcggcctgat
    10501 cgtgctcgag gatggcgtac ttgtagcgcg cccattcgcg ctcgagcgca gcgatgccct
    10561 cgtgatgcgt gcacaggatg cacttgaggg ccgaaaggtt cttgtccttc acttccagca
    10621 tgatgtcggg gagcgaggag ttgtcgccgt tttcgctcgt cgcgctgcga aacgcgacga
    10681 gttcctggta gaacgcgagg aaggcgtcga tgccgatggt gtcggcatgg ctgcccggcc
    10741 ggcgccccgg cgcctgttgc gcgtagtgca ttttctgagg accgtcctgc gcatgccacg
    10801 ttgcgcgcgc ttcgtcgagc agctcgagcc aaccggggct gtcgggttcg tggttgagct
    10861 cgtggtgcag
//
