GCF_025402875.1_ASM2540287v1_genomic - 5 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP104755.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	siderophore	1,760,352	1,772,280	putrebactin / avaroferrin	Other	40%
Region 1.2	RiPP-like	1,905,783	1,916,631
Region 1.3	betalactone	2,603,306	2,632,920	bacillomycin D	Polyketide + NRP:Lipopeptide	20%
Region 1.4	hglE-KS,PUFA	3,050,978	3,107,367	eicosapentaenoic acid	Other	100%
Region 1.5	arylpolyene	4,146,958	4,190,793	APE Vf	Other	40%

No secondary metabolite regions were found in these records:: NZ_CP104756.1

Compact view

NZ_CP104755.1 - Region 1 - siderophore

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Location: 1,760,352 - 1,772,280 nt. (total: 11,929 nt) Show pHMM detection rules used

siderophore: IucA_IucC

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core biosynthetic genes

additional biosynthetic genes

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001572.1	0.30	Other	desferrioxamine E	Pantoea agglomerans
BGC0001478.1	0.24	Other	desferrioxamine E	Streptomyces sp. ID38640
BGC0000941.1	0.23	Other	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001453.1	0.23	Other	desferrioxamine	Streptomyces argillaceus
BGC0000940.1	0.23	Other	desferrioxamin B, desferrioxamine E	Streptomyces coelicolor A3(2)
BGC0001713.1	0.19	Other	ochrobactin	Ochrobactrum anthropi
BGC0001499.1	0.18	Other	aerobactin	Pantoea ananatis
BGC0000939.1	0.16	Other	aerobactin	Grimontia hollisae
BGC0000244.1	0.15	Polyketide	macrotetrolide	Streptomyces griseus subsp. griseus
BGC0000294.1	0.15	NRP	acinetobactin	Acinetobacter baumannii

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001572.1	0.63	Other	desferrioxamine E	Pantoea agglomerans
BGC0001478.1	0.58	Other	desferrioxamine E	Streptomyces sp. ID38640
BGC0000941.1	0.56	Other	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001453.1	0.56	Other	desferrioxamine	Streptomyces argillaceus
BGC0000940.1	0.56	Other	desferrioxamin B, desferrioxamine E	Streptomyces coelicolor A3(2)
BGC0001713.1	0.51	Other	ochrobactin	Ochrobactrum anthropi
BGC0001499.1	0.49	Other	aerobactin	Pantoea ananatis
BGC0000939.1	0.47	Other	aerobactin	Grimontia hollisae
BGC0000244.1	0.46	Polyketide	macrotetrolide	Streptomyces griseus subsp. griseus
BGC0000294.1	0.45	NRP	acinetobactin	Acinetobacter baumannii

Similar known gene clusters

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_CP104755.1 - Region 2 - RiPP-like

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Location: 1,905,783 - 1,916,631 nt. (total: 10,849 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	RiPP-like	Similarity score	Type	Compound(s)	Organism
BGC0001387.1		0.17	Other	nucleocidin	Streptomyces calvus

Reference	Aggregated	Similarity score	Type	Compound(s)	Organism
BGC0001387.1		0.49	Other	nucleocidin	Streptomyces calvus

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_CP104755.1 - Region 3 - betalactone

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Location: 2,603,306 - 2,632,920 nt. (total: 29,615 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001778.1	0.26	Other	showdomycin	Streptomyces showdoensis
BGC0000234.1	0.20	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000890.1	0.20	Other (Aminocoumarin)	pentabromopseudilin	Pseudoalteromonas phenolica O-BC30
BGC0001465.1	0.20	Other	bromopyrroles/bromophenols	Marinomonas mediterranea MMB-1
BGC0000891.1	0.19	Other (Aminocoumarin)	pentabromopseudilin	Pseudoalteromonas luteoviolacea 2ta16
BGC0000260.1	0.18	Polyketide	prodigiosin	Hahella chejuensis KCTC 2396
BGC0000732.1	0.17	Saccharide	capsular polysaccharide	Raoultella planticola
BGC0000788.1	0.17	Saccharide	O-antigen	Salmonella enterica subsp. salamae serovar Greenside
BGC0000791.1	0.17	Saccharide	O-antigen	Cronobacter sakazakii
BGC0000733.1	0.17	Saccharide	capsular polysaccharide	Klebsiella pneumoniae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001778.1	0.60	Other	showdomycin	Streptomyces showdoensis
BGC0000234.1	0.52	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000890.1	0.52	Other (Aminocoumarin)	pentabromopseudilin	Pseudoalteromonas phenolica O-BC30
BGC0001465.1	0.52	Other	bromopyrroles/bromophenols	Marinomonas mediterranea MMB-1
BGC0000891.1	0.52	Other (Aminocoumarin)	pentabromopseudilin	Pseudoalteromonas luteoviolacea 2ta16
BGC0000260.1	0.50	Polyketide	prodigiosin	Hahella chejuensis KCTC 2396
BGC0000732.1	0.48	Saccharide	capsular polysaccharide	Raoultella planticola
BGC0000788.1	0.48	Saccharide	O-antigen	Salmonella enterica subsp. salamae serovar Greenside
BGC0000791.1	0.48	Saccharide	O-antigen	Cronobacter sakazakii
BGC0000733.1	0.48	Saccharide	capsular polysaccharide	Klebsiella pneumoniae

Similar known gene clusters

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_CP104755.1 - Region 4 - PUFA,hglE-KS

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Location: 3,050,978 - 3,107,367 nt. (total: 56,390 nt) Show pHMM detection rules used

hglE-KS: (hglE or hglD)
PUFA: PUFA_KS

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core biosynthetic genes

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Gene details

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000861.1	1.29	Other	eicosapentaenoic acid	Shewanella sp. BR-2
BGC0000862.1	0.73	Other	eicosapentaenoic acid	Shewanella pneumatophori
BGC0000863.1	0.49	Other	eicosapentaenoic acid	Pseudoalteromonas sp. DS-12
BGC0000284.1	0.48	Polyketide	phenolic lipids	Azotobacter vinelandii DJ
BGC0000869.1	0.46	Other	heterocyst glycolipids	Nostoc sp. 'Peltigera membranacea cyanobiont'
BGC0001872.1	0.42	Polyketide	fabclavine-polyamine	Xenorhabdus bovienii SS-2004
BGC0000865.1	0.41	Other	eicoseicosapentaenoic acid	Photobacterium profundum SS9
BGC0000864.1	0.41	Other	eicosapentaenoic acid-like compound	Moritella marina ATCC 15381
BGC0001403.1	0.38	Polyketide	trypacidin	Aspergillus fumigatus Af293
BGC0001264.1	0.37	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000861.1	0.86	Other	eicosapentaenoic acid	Shewanella sp. BR-2
BGC0000862.1	0.69	Other	eicosapentaenoic acid	Shewanella pneumatophori
BGC0000863.1	0.58	Other	eicosapentaenoic acid	Pseudoalteromonas sp. DS-12
BGC0000284.1	0.57	Polyketide	phenolic lipids	Azotobacter vinelandii DJ
BGC0000869.1	0.56	Other	heterocyst glycolipids	Nostoc sp. 'Peltigera membranacea cyanobiont'
BGC0001872.1	0.54	Polyketide	fabclavine-polyamine	Xenorhabdus bovienii SS-2004
BGC0000864.1	0.53	Other	eicosapentaenoic acid-like compound	Moritella marina ATCC 15381
BGC0001403.1	0.52	Polyketide	trypacidin	Aspergillus fumigatus Af293
BGC0000865.1	0.52	Other	eicoseicosapentaenoic acid	Photobacterium profundum SS9
BGC0001292.1	0.52	Other	A33853	Streptomyces sp. NRRL 12068

Similar known gene clusters

Module view

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Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 4, location 3050977 - 3107367:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_2636

PKS_AT (620..939): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 70.8%; 2-Rhyd-Malonyl-CoA: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 92.2
inactive: 33.4
Methoxymalonyl-CoA: 31.1
Methylmalonyl-CoA: 21.4
fatty_acid: 17.6
CHC-CoA: 12.3
Isobutyryl-CoA: 11.9
Propionyl-CoA: 3.7
trans-1,2-CPDA: 0.0
Ethylmalonyl-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg1_2637

PKS_AT (374..686): pk

ATSignature: (unknown)

No matches above 50%

minowa: trans-1,2-CPDA

Prediction, score:

trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

NZ_CP104755.1 - Region 5 - arylpolyene

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Location: 4,146,958 - 4,190,793 nt. (total: 43,836 nt) Show pHMM detection rules used

arylpolyene: (APE_KS1 or APE_KS2)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002008.1	0.32	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0000836.1	0.28	Other	APE Ec	Escherichia coli CFT073
BGC0000231.1	0.24	Polyketide	griseusin	Streptomyces griseus
BGC0000234.1	0.23	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000228.1	0.22	Polyketide	granaticin	Streptomyces violaceoruber
BGC0000272.1	0.22	Polyketide	spore pigment	Streptomyces collinus
BGC0000248.1	0.21	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000886.1	0.20	Other	allylmalonyl-CoA	Streptomyces tsukubensis
BGC0000261.1	0.19	Polyketide	R1128	Streptomyces sp. R1128
BGC0001895.1	0.19	Polyketide	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002008.1	0.65	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0000836.1	0.62	Other	APE Ec	Escherichia coli CFT073
BGC0000231.1	0.58	Polyketide	griseusin	Streptomyces griseus
BGC0000234.1	0.56	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000228.1	0.55	Polyketide	granaticin	Streptomyces violaceoruber
BGC0000272.1	0.54	Polyketide	spore pigment	Streptomyces collinus
BGC0000248.1	0.54	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000886.1	0.52	Other	allylmalonyl-CoA	Streptomyces tsukubensis
BGC0000261.1	0.51	Polyketide	R1128	Streptomyces sp. R1128
BGC0001895.1	0.51	Polyketide	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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