LOCUS       c00001_NZ_JACH..       21697 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JACHHH010000001.1 Oribacterium sinus strain DSM 17245
            Ga0415240_01, whole genome shotgun sequence.
ACCESSION   c00001_NZ_JACH..
VERSION     c00001_NZ_JACH..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:51:57
            Original ID  :: NZ_JACHHH010000001.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 284947
            Orig. end    :: 306644
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21697
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[294947:296644]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11697
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21697
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21697
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /tool="antismash"
     CDS             706..1455
                     /locus_tag="ctg1_234"
                     /transl_table=11
                     /translation="MRKKIIAGNWKMNMTVTEAKALCDKLLPLVNTDAVDVVFCVPAID
                     IVPVVEKLQSSKISVGAENLYFEEAGAYTGEISANMLVDAGVKYVIMGHSERRGYFHET
                     DEDINKKAKKALEKGLTPIICCGESLEQREMGIYFEWISMQIKAAFQGISAEDAGKCVI
                     AYEPIWAIGTGKTATAEQAEEVCAYIRKVICEIYSQAVGEKIRIQYGGSMNAGNCKELL
                     SKPNIDGGLIGGASLKEEFAKIVNYQD"
     PFAM_domain     715..1446
                     /aSDomain="TIM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00121.20"
                     /description="Triosephosphate isomerase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_234_0001"
                     /evalue="3.30E-93"
                     /label="ctg1_234"
                     /locus_tag="ctg1_234"
                     /protein_end="247"
                     /protein_start="3"
                     /score="311.8"
                     /tool="antismash"
                     /translation="KIIAGNWKMNMTVTEAKALCDKLLPLVNTDAVDVVFCVPAIDIVP
                     VVEKLQSSKISVGAENLYFEEAGAYTGEISANMLVDAGVKYVIMGHSERRGYFHETDED
                     INKKAKKALEKGLTPIICCGESLEQREMGIYFEWISMQIKAAFQGISAEDAGKCVIAYE
                     PIWAIGTGKTATAEQAEEVCAYIRKVICEIYSQAVGEKIRIQYGGSMNAGNCKELLSKP
                     NIDGGLIGGASLKEEFAKIVNY"
     aSDomain        718..1422
                     /aSDomain="TIGR00419"
                     /aSTool="tigrfam"
                     /description="tim: triose-phosphate isomerase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_234_0001"
                     /evalue="1.60E-60"
                     /identifier="TIGR00419"
                     /label="ctg1_234"
                     /locus_tag="ctg1_234"
                     /protein_end="239"
                     /protein_start="4"
                     /score="202.7"
                     /tool="antismash"
                     /translation="IIAGNWKMNMTVTEAKALCDKLLPLVNTDAVDVVFCVPAIDIVPV
                     VEKLQSSKISVGAENLYFEEAGAYTGEISANMLVDAGVKYVIMGHSERRGYFHETDEDI
                     NKKAKKALEKGLTPIICCGESLEQREMGIYFEWISMQIKAAFQGISAEDAGKCVIAYEP
                     IWAIGTGKTATAEQAEEVCAYIRKVICEIYSQAVGEKIRIQYGGSMNAGNCKELLSKPN
                     IDGGLIGGASLKE"
     CDS             complement(2016..3611)
                     /locus_tag="ctg1_235"
                     /transl_table=11
                     /translation="MRENFQNIDGKKLEIVHEIKSAYDEGKISLEEARKALKDRVQHLA
                     PYEIAIIEQEMVEETEDECIKEDIQAMLEVFQDVLVTKDQELPENHPISCYRRENAKMK
                     ELLFSVEDLVQYPLIKNQWLELYEELLKFKIHLSRKQNQLYPVLEKKGFTRPTTTMWTL
                     DDFIRDEIAECYKLLLEDKEEEFIGKQAELVADVRDLMDKEENILYPTSLEMISDEEFR
                     YMAEGDREIGFAYITVEPEKSPKQNVSHTASQSTSPLSGLSSAPGFAEELAGLLGKYGF
                     NNKEEKLNVTTGQLTLEQINLIYQHMPVDLSYVDENELVCFYTDTKHRVFPRSKNVIGR
                     DVKNCHPKASVHIVEEIIKKFRSGEQDKAEFWINKPDLFIYIIYYAVRDENGKFRGVLE
                     MMQDCTHIRSLQGSQTLLTWEQQEKGESKETSEDEDKREGSKTSEDVGNKESAGTLAAG
                     KLTEINEDTLLKDILEADPNVKTLLFRLSDRFKALNTPLARIMMPKATVKIMSERAEVD
                     LDTLLRELREYFKL"
     PFAM_domain     complement(2046..2225)
                     /aSDomain="DUF1858"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08984.13"
                     /description="Domain of unknown function (DUF1858)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_235_0004"
                     /evalue="6.00E-08"
                     /label="ctg1_235"
                     /locus_tag="ctg1_235"
                     /protein_end="522"
                     /protein_start="462"
                     /score="32.8"
                     /tool="antismash"
                     /translation="INEDTLLKDILEADPNVKTLLFRLSDRFKALNTPLARIMMPKATV
                     KIMSERAEVDLDTLL"
     PFAM_domain     complement(2400..2714)
                     /aSDomain="PAS_10"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13596.8"
                     /description="PAS domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_235_0003"
                     /evalue="1.60E-25"
                     /label="ctg1_235"
                     /locus_tag="ctg1_235"
                     /protein_end="404"
                     /protein_start="299"
                     /score="89.8"
                     /tool="antismash"
                     /translation="INLIYQHMPVDLSYVDENELVCFYTDTKHRVFPRSKNVIGRDVKN
                     CHPKASVHIVEEIIKKFRSGEQDKAEFWINKPDLFIYIIYYAVRDENGKFRGVLEMMQD
                     C"
     PFAM_domain     complement(2979..3341)
                     /aSDomain="Hemerythrin"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01814.25"
                     /description="Hemerythrin HHE cation binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_235_0002"
                     /evalue="3.70E-09"
                     /label="ctg1_235"
                     /locus_tag="ctg1_235"
                     /protein_end="211"
                     /protein_start="90"
                     /score="37.4"
                     /tool="antismash"
                     /translation="HPISCYRRENAKMKELLFSVEDLVQYPLIKNQWLELYEELLKFKI
                     HLSRKQNQLYPVLEKKGFTRPTTTMWTLDDFIRDEIAECYKLLLEDKEEEFIGKQAELV
                     ADVRDLMDKEENILYPT"
     CDS             4134..6284
                     /locus_tag="ctg1_236"
                     /transl_table=11
                     /translation="MKKMTKGVILSLAFVLPTILVQGKAFAAETANTGEWKAMNGKWFY
                     EKEGKPVKDWLMDKGNWYYLSQDSGEMLLGSQDIKGANYYFQNKNEAVEGSMARGWHQD
                     SKGAYRFYDNREGSPTEGQELRGWQWIDGYCYYFEEEEGEKKGILLQNGMSKDGYTVNE
                     EGQWTVNGVVQFVEGKGFITKKSDVKGVSRTIENTEARPERTSSTRSHSGRRSSGAGSN
                     GSGNINRNGSNAGASGNAGASSSGVGEQDKKNSKTELPQENSKAENSKVETGKENPDKK
                     AESLLADGVFYGTGTWSRYYEQSGPDIVKVSIKDGKIAEVSNVKYTEDDSYQDKTFKIF
                     DYLKGLEDVKELEKNLKEKKGEAYDAVASATQSTLGEVSAVDNALARSRKLKKDKKEQK
                     IAYFDFTRKPNARAVGDSLDLSDTILDLHFADVSRQDVPYADFAKHGITVDKEQGSPLP
                     EIGTTFPVYFQNEDSLIKLPSFIQVQKDYRWAYADEIRLTYENGEVKTLPTDKDHFVYR
                     AVETGKDIIKAELLRGGKVLTEGVYDANRSVWDFQLDDKQLPKDYDAWRYKDIQLKEVM
                     DEGKIPASVELLYDGEYILEDTIHLEKEAILSGEVLEKDGDVNLDYFDEIEKNPALLLG
                     EAENENEKTVKVELRYIPDKTEKKVSGEGNSENGDGEEEKNATVELSFPDLIIKGKTAK
                     LILRLHYVSIEEEGEDGAVETE"
     PFAM_domain     4230..4352
                     /aSDomain="Choline_bind_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF19127.2"
                     /description="Choline-binding repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_236_0005"
                     /evalue="1.80E-07"
                     /label="ctg1_236"
                     /locus_tag="ctg1_236"
                     /protein_end="73"
                     /protein_start="32"
                     /score="31.2"
                     /tool="antismash"
                     /translation="TGEWKAMNGKWFYEKEGKPVKDWLMDKGNWYYLSQDSGEML"
     CDS             complement(6622..7422)
                     /locus_tag="ctg1_237"
                     /transl_table=11
                     /translation="MSKDLHFTENKNKSGKSFLGALFQKNQKLATEKGSPKRLLFSHHF
                     FPLILFGISLQFLLFLLPILLYSYKNPKLLLPSSPLLSLCFFFTVLPLLYGGLGLLASY
                     AKKLAVFELFRKGTIVIFLLSLLSSLPLFLHPVYCSRTSSLFGKADVQEENFLYPYSES
                     LPNNSQEAIEKALSSFPDTPLYEMSFFHYGEGNIEQFQYQFFFTIDNMEDNIKLLEKKL
                     PFQQKVEEENIFYGNGRLSNELFFDISIDKKGGKTEFSFSNLPF"
     CDS             complement(7427..8485)
                     /locus_tag="ctg1_238"
                     /transl_table=11
                     /translation="MLFSSEQVSNGHPDKICDQISDAIVTDILKHDPKGRIAAECCIKD
                     YDIVILGEITSSHTPDYDTLCRNVLKNIGLEDLDRYKIQELISVQSPDIAMGVDHDGAG
                     DQGMMFGYATNETKEMLPIPYVLSTRALQKLRAFNLENAFSILKPDAKAQVSYDYKENR
                     IDTFLISSQHSESVSLSQVREIIQKIMVETAAEMNLNTDFRILVNPTGRFVLGSSFADS
                     GLTGRKIIADTYGGAAHHGGGAFSGKDPSKVDRSAAYMARKIAKDLVSAGKTDRCEVQL
                     AYAIGVAEPVSVYLDCFGTEHENVGDLWRSVIEKYDLTPKGIISNLNLLNTDYNLVSSY
                     GHFGKENLPWEI"
     PFAM_domain     complement(7433..7840)
                     /aSDomain="S-AdoMet_synt_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02773.18"
                     /description="S-adenosylmethionine synthetase, C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_238_0008"
                     /evalue="9.70E-56"
                     /label="ctg1_238"
                     /locus_tag="ctg1_238"
                     /protein_end="351"
                     /protein_start="215"
                     /score="187.6"
                     /tool="antismash"
                     /translation="GSSFADSGLTGRKIIADTYGGAAHHGGGAFSGKDPSKVDRSAAYM
                     ARKIAKDLVSAGKTDRCEVQLAYAIGVAEPVSVYLDCFGTEHENVGDLWRSVIEKYDLT
                     PKGIISNLNLLNTDYNLVSSYGHFGKENLPWE"
     aSDomain        complement(7433..8482)
                     /aSDomain="TIGR01034"
                     /aSTool="tigrfam"
                     /description="metK: methionine adenosyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_238_0002"
                     /evalue="3.50E-127"
                     /identifier="TIGR01034"
                     /label="ctg1_238"
                     /locus_tag="ctg1_238"
                     /protein_end="351"
                     /protein_start="1"
                     /score="422.4"
                     /tool="antismash"
                     /translation="LFSSEQVSNGHPDKICDQISDAIVTDILKHDPKGRIAAECCIKDY
                     DIVILGEITSSHTPDYDTLCRNVLKNIGLEDLDRYKIQELISVQSPDIAMGVDHDGAGD
                     QGMMFGYATNETKEMLPIPYVLSTRALQKLRAFNLENAFSILKPDAKAQVSYDYKENRI
                     DTFLISSQHSESVSLSQVREIIQKIMVETAAEMNLNTDFRILVNPTGRFVLGSSFADSG
                     LTGRKIIADTYGGAAHHGGGAFSGKDPSKVDRSAAYMARKIAKDLVSAGKTDRCEVQLA
                     YAIGVAEPVSVYLDCFGTEHENVGDLWRSVIEKYDLTPKGIISNLNLLNTDYNLVSSYG
                     HFGKENLPWE"
     PFAM_domain     complement(7847..8185)
                     /aSDomain="S-AdoMet_synt_M"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02772.18"
                     /description="S-adenosylmethionine synthetase, central
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_238_0007"
                     /evalue="6.10E-32"
                     /label="ctg1_238"
                     /locus_tag="ctg1_238"
                     /protein_end="213"
                     /protein_start="100"
                     /score="110.4"
                     /tool="antismash"
                     /translation="DGAGDQGMMFGYATNETKEMLPIPYVLSTRALQKLRAFNLENAFS
                     ILKPDAKAQVSYDYKENRIDTFLISSQHSESVSLSQVREIIQKIMVETAAEMNLNTDFR
                     ILVNPTGRF"
     PFAM_domain     complement(8213..8482)
                     /aSDomain="S-AdoMet_synt_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00438.22"
                     /description="S-adenosylmethionine synthetase, N-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_238_0006"
                     /evalue="1.30E-25"
                     /label="ctg1_238"
                     /locus_tag="ctg1_238"
                     /protein_end="91"
                     /protein_start="1"
                     /score="89.9"
                     /tool="antismash"
                     /translation="LFSSEQVSNGHPDKICDQISDAIVTDILKHDPKGRIAAECCIKDY
                     DIVILGEITSSHTPDYDTLCRNVLKNIGLEDLDRYKIQELISVQS"
     CDS             8905..9717
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1179:hydrolase (Score: 194; E-value: 6.1e-59)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_239"
                     /transl_table=11
                     /translation="MFKAIALDLDGTLTNSEKKVSERNKKALQEAVKRGVSIILASGRP
                     TYGMSEVWEALELEKLGGYVLSYNGSLCMDCKSKEVLFEKTIPRKYYEPIAKAVREADL
                     GLLSYQGKEIVTERPEFPYMDRESTINKMPFRKVEDFPNALSEEVCKLLALGEHEELLP
                     LKERLEKEYGEELSIFFSEPFFLEICPLGVDKGESLKRLLEKKGWKREELMAFGDGGND
                     LTMLEYAGKGIAMANSQKHVLEIADEITLSNDEDGVAVMVEKYILSNI"
     aSDomain        8917..9609
                     /aSDomain="TIGR01484"
                     /aSTool="tigrfam"
                     /description="HAD-SF-IIB: HAD hydrolase, family IIB"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_239_0004"
                     /evalue="9.60E-27"
                     /identifier="TIGR01484"
                     /label="ctg1_239"
                     /locus_tag="ctg1_239"
                     /protein_end="235"
                     /protein_start="4"
                     /score="92.4"
                     /tool="antismash"
                     /translation="IALDLDGTLTNSEKKVSERNKKALQEAVKRGVSIILASGRPTYGM
                     SEVWEALELEKLGGYVLSYNGSLCMDCKSKEVLFEKTIPRKYYEPIAKAVREADLGLLS
                     YQGKEIVTERPEFPYMDRESTINKMPFRKVEDFPNALSEEVCKLLALGEHEELLPLKER
                     LEKEYGEELSIFFSEPFFLEICPLGVDKGESLKRLLEKKGWKREELMAFGDGGNDLTML
                     EYAGKGIAM"
     aSDomain        8917..9684
                     /aSDomain="TIGR00099"
                     /aSTool="tigrfam"
                     /description="Cof-subfamily: Cof-like hydrolase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_239_0003"
                     /evalue="6.40E-61"
                     /identifier="TIGR00099"
                     /label="ctg1_239"
                     /locus_tag="ctg1_239"
                     /protein_end="260"
                     /protein_start="4"
                     /score="204.1"
                     /tool="antismash"
                     /translation="IALDLDGTLTNSEKKVSERNKKALQEAVKRGVSIILASGRPTYGM
                     SEVWEALELEKLGGYVLSYNGSLCMDCKSKEVLFEKTIPRKYYEPIAKAVREADLGLLS
                     YQGKEIVTERPEFPYMDRESTINKMPFRKVEDFPNALSEEVCKLLALGEHEELLPLKER
                     LEKEYGEELSIFFSEPFFLEICPLGVDKGESLKRLLEKKGWKREELMAFGDGGNDLTML
                     EYAGKGIAMANSQKHVLEIADEITLSNDEDGVAV"
     PFAM_domain     8917..9684
                     /aSDomain="Hydrolase_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08282.14"
                     /description="haloacid dehalogenase-like hydrolase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_239_0009"
                     /evalue="3.60E-66"
                     /label="ctg1_239"
                     /locus_tag="ctg1_239"
                     /protein_end="260"
                     /protein_start="4"
                     /score="223.6"
                     /tool="antismash"
                     /translation="IALDLDGTLTNSEKKVSERNKKALQEAVKRGVSIILASGRPTYGM
                     SEVWEALELEKLGGYVLSYNGSLCMDCKSKEVLFEKTIPRKYYEPIAKAVREADLGLLS
                     YQGKEIVTERPEFPYMDRESTINKMPFRKVEDFPNALSEEVCKLLALGEHEELLPLKER
                     LEKEYGEELSIFFSEPFFLEICPLGVDKGESLKRLLEKKGWKREELMAFGDGGNDLTML
                     EYAGKGIAMANSQKHVLEIADEITLSNDEDGVAV"
     CDS             complement(10001..11383)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_240"
                     /sec_met_domain="Fer4_12 (E-value: 2.5e-13, bitscore: 44.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5.1e-20, bitscore:
                     66.1, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.7e-07, bitscore: 26.1,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 2.4e-22,
                     bitscore: 73.5, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHQYLMNGRHIVLDVYSGSIHVTDPMAYAAIGYLEKGLSREEVL
                     QKLKVEFPESTEQDFLDCFSDIDELIESKKLFTKDNYAPLAGKLKSHSGNVIKALCLLV
                     AHSCNLACSYCFASQGHYHGESGLMSFETGKRALDFLIENSGTRRNLEVDFFGGEPLVN
                     FQVCKDLVAYARSIEKEKGKNFRFTLTTNGVGLTEEIMDWANEECHNVVLSLDGRKEVN
                     DRFRVDRKGKGSYDQIVPKFQRFVEKRGDKEYYMRGTFSHFNTDFTEDIAHMADELGFK
                     ELSMEPVVLKPGEPSALTEEDLPILYEQYEKLALDLLRRKKAGDPVTFYHYMVDLDRGP
                     CIYKRISGCGSGTEYMAVSAQGELYPCHQFVSDKEYKLGDIWNGITKEEAREEFRNTNV
                     YTREDCGKCWAKLYCAGGCAANAYHSTGDIAGTYEYGCKLFRKRMECAIMMKVEESLME
                     QG"
     aSDomain        complement(10028..11380)
                     /aSDomain="TIGR03974"
                     /aSTool="tigrfam"
                     /description="rSAM_six_Cys: SCIFF radical SAM maturase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_240_0005"
                     /evalue="3.40E-221"
                     /identifier="TIGR03974"
                     /label="ctg1_240"
                     /locus_tag="ctg1_240"
                     /protein_end="452"
                     /protein_start="1"
                     /score="732.8"
                     /tool="antismash"
                     /translation="IHQYLMNGRHIVLDVYSGSIHVTDPMAYAAIGYLEKGLSREEVLQ
                     KLKVEFPESTEQDFLDCFSDIDELIESKKLFTKDNYAPLAGKLKSHSGNVIKALCLLVA
                     HSCNLACSYCFASQGHYHGESGLMSFETGKRALDFLIENSGTRRNLEVDFFGGEPLVNF
                     QVCKDLVAYARSIEKEKGKNFRFTLTTNGVGLTEEIMDWANEECHNVVLSLDGRKEVND
                     RFRVDRKGKGSYDQIVPKFQRFVEKRGDKEYYMRGTFSHFNTDFTEDIAHMADELGFKE
                     LSMEPVVLKPGEPSALTEEDLPILYEQYEKLALDLLRRKKAGDPVTFYHYMVDLDRGPC
                     IYKRISGCGSGTEYMAVSAQGELYPCHQFVSDKEYKLGDIWNGITKEEAREEFRNTNVY
                     TREDCGKCWAKLYCAGGCAANAYHSTGDIAGTYEYGCKLFRKRMECAIMMKV"
     aSDomain        complement(10073..10339)
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_240_0006"
                     /evalue="6.60E-19"
                     /identifier="TIGR04085"
                     /label="ctg1_240"
                     /locus_tag="ctg1_240"
                     /protein_end="437"
                     /protein_start="348"
                     /score="66.1"
                     /tool="antismash"
                     /translation="CGSGTEYMAVSAQGELYPCHQFVSDKEYKLGDIWNGITKEEAREE
                     FRNTNVYTREDCGKCWAKLYCAGGCAANAYHSTGDIAGTYEYGC"
     PFAM_domain     complement(10157..10339)
                     /aSDomain="SPASM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13186.8"
                     /description="Iron-sulfur cluster-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_240_0011"
                     /evalue="9.60E-06"
                     /label="ctg1_240"
                     /locus_tag="ctg1_240"
                     /protein_end="409"
                     /protein_start="348"
                     /score="26.1"
                     /tool="antismash"
                     /translation="CGSGTEYMAVSAQGELYPCHQFVSDKEYKLGDIWNGITKEEAREE
                     FRNTNVYTREDCGKCW"
     PFAM_domain     complement(10667..11083)
                     /aSDomain="Fer4_12"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13353.8"
                     /description="4Fe-4S single cluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_240_0010"
                     /evalue="2.70E-12"
                     /label="ctg1_240"
                     /locus_tag="ctg1_240"
                     /protein_end="239"
                     /protein_start="100"
                     /score="47.4"
                     /tool="antismash"
                     /translation="CLLVAHSCNLACSYCFASQGHYHGESGLMSFETGKRALDFLIENS
                     GTRRNLEVDFFGGEPLVNFQVCKDLVAYARSIEKEKGKNFRFTLTTNGVGLTEEIMDWA
                     NEECHNVVLSLDGRKEVNDRFRVDRKGKGSYDQIV"
     CDS             complement(11551..11697)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_241"
                     /sec_met_domain="TIGR03973 (E-value: 2.9e-25, bitscore:
                     82.4, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 2.9e-25, bitscore: 82.4,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHIITLSTRDLEKSVEHGGCGECQTSCQSACKTSCGIANQNCEN
                     ENN"
     PFAM_domain     complement(11563..11694)
                     /aSDomain="SCIFF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13165.8"
                     /description="Six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_241_0012"
                     /evalue="1.60E-23"
                     /label="ctg1_241"
                     /locus_tag="ctg1_241"
                     /protein_end="45"
                     /protein_start="1"
                     /score="82.4"
                     /tool="antismash"
                     /translation="KHIITLSTRDLEKSVEHGGCGECQTSCQSACKTSCGIANQNCEN"
     aSDomain        complement(11566..11694)
                     /aSDomain="TIGR03973"
                     /aSTool="tigrfam"
                     /description="six_Cys_in_45: six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_241_0007"
                     /evalue="3.80E-24"
                     /identifier="TIGR03973"
                     /label="ctg1_241"
                     /locus_tag="ctg1_241"
                     /protein_end="44"
                     /protein_start="1"
                     /score="82.4"
                     /tool="antismash"
                     /translation="KHIITLSTRDLEKSVEHGGCGECQTSCQSACKTSCGIANQNCE"
     CDS             11872..13176
                     /locus_tag="ctg1_242"
                     /transl_table=11
                     /translation="MGLIKAGKEAGISVLADQWREYFYCSSLDNDTLMTKGHKRIGQNS
                     SNTRASDNIISNGAVIAVNEGQCMLIVEQGAIVELSAEAGEFVFDSSTEPSIFYGSLGE
                     SVVESFKTFMKRLSFGGDTAKDQRIYFINLKDIVGNKYGTVNPIPFRAVDPNINLDIEI
                     SLRCHGEYAYKITDPVLFYRNLAGNVEGDYKKEEVESQLKSELLTNLQPAFSRISEQGI
                     RYHSILSHTDDIAHALNDILSSTWGGHYGIKITSFGISSIKAPEEDEKMIKEMQRDAVF
                     RDPSMAAAYLSKAQGDAMKLAAGNTATGPMMAFAGMNMANQTGGFNASELFSMGAKQGN
                     AQAGQNTANQANAGAQGSIFGQVSVPMQETANGAVPTAEAGTAEDWTCAKCGHTHNTGK
                     FCSECGEARADKWNCPECGHTGNVGKFCPECGHKR"
     PFAM_domain     12025..12696
                     /aSDomain="Band_7_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13421.8"
                     /description="SPFH domain-Band 7 family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_242_0013"
                     /evalue="2.40E-19"
                     /label="ctg1_242"
                     /locus_tag="ctg1_242"
                     /protein_end="275"
                     /protein_start="51"
                     /score="69.9"
                     /tool="antismash"
                     /translation="DNIISNGAVIAVNEGQCMLIVEQGAIVELSAEAGEFVFDSSTEPS
                     IFYGSLGESVVESFKTFMKRLSFGGDTAKDQRIYFINLKDIVGNKYGTVNPIPFRAVDP
                     NINLDIEISLRCHGEYAYKITDPVLFYRNLAGNVEGDYKKEEVESQLKSELLTNLQPAF
                     SRISEQGIRYHSILSHTDDIAHALNDILSSTWGGHYGIKITSFGISSIKAPEEDEKMIK
                     EM"
     CDS             13299..13616
                     /locus_tag="ctg1_243"
                     /transl_table=11
                     /translation="MDKELLGWLSPKGDFFPTDWGKHCMEAERILMKLGLYEEFSKQSL
                     FNAGDFLSGRGYVLLHNPSKKKLMATALCPLSKAQRNFLYGYFLELGKSKEAKYYLEEA
                     F"
     CDS             13720..14727
                     /locus_tag="ctg1_244"
                     /transl_table=11
                     /translation="MALVIPKDYSPRLSVRETQEAIKYIRDTFQKEFGKEMNLSRISAP
                     LFVEKSSGLNDNLNGVERPVSFDVPWKKEEVVEVVQSLAKWKRIALKRYNFQVGEGLYT
                     NMNAIRRDEELDNLHSCYVDQWDWERVIGKDERTEEVLQNTVRDIFRIIKHMEHQVWYK
                     YPDAVKKLPEEIYFIDSEELLKRYPNLSPKERENAITKEHGCVFIQRIGDKLSNGEPHD
                     GRAPDYDDWSLNGDILFWFETLNCALEISSMGIRVDEKALERQLKLSHNEDRAKLPYHK
                     MLLEGKLPQTIGGGIGQSRLCMLLLDRAHVGEVQASIWPEEMRKLCEENNIFLL"
     aSDomain        13771..14697
                     /aSDomain="TIGR00669"
                     /aSTool="tigrfam"
                     /description="asnA: aspartate--ammonia ligase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_244_0008"
                     /evalue="2.50E-111"
                     /identifier="TIGR00669"
                     /label="ctg1_244"
                     /locus_tag="ctg1_244"
                     /protein_end="326"
                     /protein_start="17"
                     /score="370.1"
                     /tool="antismash"
                     /translation="TQEAIKYIRDTFQKEFGKEMNLSRISAPLFVEKSSGLNDNLNGVE
                     RPVSFDVPWKKEEVVEVVQSLAKWKRIALKRYNFQVGEGLYTNMNAIRRDEELDNLHSC
                     YVDQWDWERVIGKDERTEEVLQNTVRDIFRIIKHMEHQVWYKYPDAVKKLPEEIYFIDS
                     EELLKRYPNLSPKERENAITKEHGCVFIQRIGDKLSNGEPHDGRAPDYDDWSLNGDILF
                     WFETLNCALEISSMGIRVDEKALERQLKLSHNEDRAKLPYHKMLLEGKLPQTIGGGIGQ
                     SRLCMLLLDRAHVGEVQASIWPEEMRKL"
     PFAM_domain     13774..14454
                     /aSDomain="AsnA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03590.17"
                     /description="Aspartate-ammonia ligase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_244_0014"
                     /evalue="7.70E-107"
                     /label="ctg1_244"
                     /locus_tag="ctg1_244"
                     /protein_end="245"
                     /protein_start="18"
                     /score="356.3"
                     /tool="antismash"
                     /translation="QEAIKYIRDTFQKEFGKEMNLSRISAPLFVEKSSGLNDNLNGVER
                     PVSFDVPWKKEEVVEVVQSLAKWKRIALKRYNFQVGEGLYTNMNAIRRDEELDNLHSCY
                     VDQWDWERVIGKDERTEEVLQNTVRDIFRIIKHMEHQVWYKYPDAVKKLPEEIYFIDSE
                     ELLKRYPNLSPKERENAITKEHGCVFIQRIGDKLSNGEPHDGRAPDYDDWSLNGDILFW
                     FETLN"
     CDS             complement(15044..15775)
                     /locus_tag="ctg1_245"
                     /transl_table=11
                     /translation="MSIMAYYYAVKIGKNPGIYSSWAECEKQVKAYPSAKFKKWKTREE
                     AEAYMNGSGNSKPYGSDMSSISFGSKTPSSRKEKGKATLLPLQDGSLSAIEELFQSTKT
                     DCIAYVDGSFEKDNGVYGYGVVFIEKNGTIEEYFDSGREESYQSMRNVSGEILGALKAA
                     SLAVEKGYSSIAIFHDYQGIASWAKGEWKCNKEKTIEYREKMLEFQKKLIISFHKVQAH
                     SGDYFNERADLLAKQAAGINI"
     PFAM_domain     complement(15059..15463)
                     /aSDomain="RNase_H"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00075.26"
                     /description="RNase H"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_245_0016"
                     /evalue="1.10E-11"
                     /label="ctg1_245"
                     /locus_tag="ctg1_245"
                     /protein_end="239"
                     /protein_start="104"
                     /score="45.2"
                     /tool="antismash"
                     /translation="DCIAYVDGSFEKDNGVYGYGVVFIEKNGTIEEYFDSGREESYQSM
                     RNVSGEILGALKAASLAVEKGYSSIAIFHDYQGIASWAKGEWKCNKEKTIEYREKMLEF
                     QKKLIISFHKVQAHSGDYFNERADLLAKQAA"
     PFAM_domain     complement(15629..15757)
                     /aSDomain="Cauli_VI"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01693.18"
                     /description="Caulimovirus viroplasmin"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_245_0015"
                     /evalue="2.50E-18"
                     /label="ctg1_245"
                     /locus_tag="ctg1_245"
                     /protein_end="49"
                     /protein_start="6"
                     /score="66.1"
                     /tool="antismash"
                     /translation="YYAVKIGKNPGIYSSWAECEKQVKAYPSAKFKKWKTREEAEAY"
     CDS             15984..16739
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115:HAD-superfamily hydrolase, subfamily IA, variant
                     (Score: 138.6; E-value: 3.8e-42)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_246"
                     /transl_table=11
                     /translation="MGKKIKAVLFDLDGTLVNTLASLKRNMDLTMEHFSLEGVSLEETK
                     KFVGVGTKKFVERCLEKNAQIWYEKAEKWEAKDEEKAMDLDLKGDEVMELYEEAYEYYR
                     SIFPDNCTYEAEPYPGIHACLKRLEEKGIFRVCITNKPKEEASIILDKVFASDSFTLVL
                     GDNGKIPLKPNPDMLLTVCKELGISSEEAVMVGDTKTDLDAAKNAGMLSIGCLYGFRDK
                     KELEEHGAKYLVKDGEELWQVLEENFLEK"
     PFAM_domain     16005..16625
                     /aSDomain="HAD_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13419.8"
                     /description="Haloacid dehalogenase-like hydrolase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_246_0017"
                     /evalue="5.90E-31"
                     /label="ctg1_246"
                     /locus_tag="ctg1_246"
                     /protein_end="214"
                     /protein_start="7"
                     /score="108.0"
                     /tool="antismash"
                     /translation="VLFDLDGTLVNTLASLKRNMDLTMEHFSLEGVSLEETKKFVGVGT
                     KKFVERCLEKNAQIWYEKAEKWEAKDEEKAMDLDLKGDEVMELYEEAYEYYRSIFPDNC
                     TYEAEPYPGIHACLKRLEEKGIFRVCITNKPKEEASIILDKVFASDSFTLVLGDNGKIP
                     LKPNPDMLLTVCKELGISSEEAVMVGDTKTDLDAAKNAGMLSIG"
     aSDomain        16317..16625
                     /aSDomain="TIGR01509"
                     /aSTool="tigrfam"
                     /description="HAD-SF-IA-v3: HAD hydrolase, family IA,
                     variant 3"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_246_0010"
                     /evalue="2.20E-09"
                     /identifier="TIGR01509"
                     /label="ctg1_246"
                     /locus_tag="ctg1_246"
                     /protein_end="214"
                     /protein_start="111"
                     /score="35.6"
                     /tool="antismash"
                     /translation="TYEAEPYPGIHACLKRLEEKGIFRVCITNKPKEEASIILDKVFAS
                     DSFTLVLGDNGKIPLKPNPDMLLTVCKELGISSEEAVMVGDTKTDLDAAKNAGMLSIG"
     aSDomain        16326..16610
                     /aSDomain="TIGR01549"
                     /aSTool="tigrfam"
                     /description="HAD-SF-IA-v1: HAD hydrolase, family IA,
                     variant 1"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_246_0009"
                     /evalue="8.30E-12"
                     /identifier="TIGR01549"
                     /label="ctg1_246"
                     /locus_tag="ctg1_246"
                     /protein_end="209"
                     /protein_start="114"
                     /score="43.7"
                     /tool="antismash"
                     /translation="AEPYPGIHACLKRLEEKGIFRVCITNKPKEEASIILDKVFASDSF
                     TLVLGDNGKIPLKPNPDMLLTVCKELGISSEEAVMVGDTKTDLDAAKNAG"
     CDS             16867..18126
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1178:cobalamin synthesis protein/P47K family protein
                     (Score: 134.1; E-value: 1.2e-40)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_247"
                     /transl_table=11
                     /translation="MTKIDIISGFLGAGKTTFIQKLLSDALKGENVVLIENEFGEIGVD
                     SGFLKNAGIEIREMNQGCICCSLVGDFESSLKEVIEQYHPDRILIEPSGVGKLSDILSA
                     VKTVSENLDVKLDGAVTVVDATKAKLYNKNFGEFFDDQIRFATSVVLSRMDIASGEKAQ
                     EAVNIVRGINPHANLITTALTELSGEKLLEIIGKEENLEEELLAEVKAKAAHHHEHHHD
                     HEHHHEHHHEHGESCGCGCHDEEEHHHHHEHDESCGCGCHDEEHEHHHHHEHDESCGCG
                     CHDEEHEHHHHHEHGESCGCGCHDEEEHEHHHHHHHEGCACGHDHDADEIFDSIGLEVF
                     KKVDRNHLAEILEEMAEGCAYGGIVRAKGMLACTDGTWVNFDLVPEQVEIREAGPENIG
                     KFVVIGTELKKDKIKALFND"
     PFAM_domain     16882..17403
                     /aSDomain="cobW"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02492.21"
                     /description="CobW/HypB/UreG, nucleotide-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_247_0018"
                     /evalue="4.50E-38"
                     /label="ctg1_247"
                     /locus_tag="ctg1_247"
                     /protein_end="179"
                     /protein_start="5"
                     /score="130.7"
                     /tool="antismash"
                     /translation="IISGFLGAGKTTFIQKLLSDALKGENVVLIENEFGEIGVDSGFLK
                     NAGIEIREMNQGCICCSLVGDFESSLKEVIEQYHPDRILIEPSGVGKLSDILSAVKTVS
                     ENLDVKLDGAVTVVDATKAKLYNKNFGEFFDDQIRFATSVVLSRMDIASGEKAQEAVNI
                     VRGINPHANLI"
     PFAM_domain     17866..18120
                     /aSDomain="CobW_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07683.16"
                     /description="Cobalamin synthesis protein cobW C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_247_0019"
                     /evalue="1.20E-06"
                     /label="ctg1_247"
                     /locus_tag="ctg1_247"
                     /protein_end="418"
                     /protein_start="333"
                     /score="28.5"
                     /tool="antismash"
                     /translation="SIGLEVFKKVDRNHLAEILEEMAEGCAYGGIVRAKGMLACTDGTW
                     VNFDLVPEQVEIREAGPENIGKFVVIGTELKKDKIKALFN"
     CDS             18215..19249
                     /locus_tag="ctg1_248"
                     /transl_table=11
                     /translation="MGEQWEAEGEGIPVFLINGFLEVGKSSFIQFTMEQEYFQTEGNTL
                     LLLCEDGEVEYDPIKLAAHHTTPVYMENITDFQEDKLQSLARQYKAERVLIEWNGMWNQ
                     DDLYGGPMSEEVLAKQQNREPKYHVSMPKNWFLYQVITILDGSSLKIYLSNMRSFLGQM
                     LRHAELCIVNRCDNLSNEELVDYRRKIRAMGQNAMILLEDKNGEIPQTALPEDLPYDLG
                     QDAITLADEDYGTWFLDCMENPERYLNKEITFSAMILKRKNMPENEFVPGRMAMTCCAE
                     DMTFLGFICKGDKKLIAPFSTRDWAKLTAKVKLEKREEYHGIGPVLHLEKIARTGEIKE
                     PVNF"
     PFAM_domain     18251..18793
                     /aSDomain="cobW"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02492.21"
                     /description="CobW/HypB/UreG, nucleotide-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_248_0020"
                     /evalue="2.30E-04"
                     /label="ctg1_248"
                     /locus_tag="ctg1_248"
                     /protein_end="193"
                     /protein_start="12"
                     /score="20.9"
                     /tool="antismash"
                     /translation="PVFLINGFLEVGKSSFIQFTMEQEYFQTEGNTLLLLCEDGEVEYD
                     PIKLAAHHTTPVYMENITDFQEDKLQSLARQYKAERVLIEWNGMWNQDDLYGGPMSEEV
                     LAKQQNREPKYHVSMPKNWFLYQVITILDGSSLKIYLSNMRSFLGQMLRHAELCIVNRC
                     DNLSNEELVDYRRKIRAM"
     CDS             19403..19891
                     /locus_tag="ctg1_249"
                     /transl_table=11
                     /translation="MSYLQIFALLGAFLIPFILLWLICYGLEAYALYTLAKNNGQEDKA
                     ILAFIPYVNRGLYAYFAGDQEMFGNQVPTIASAAIMGVLPLLGGFVGGALWGLVGIIFT
                     IVVIIVSFYNYKAVYGKMSSVSDSTLFGVLAAVISLCRVIFIFLHRNDILVEDGDIVE"
     CDS             20076..20921
                     /locus_tag="ctg1_250"
                     /transl_table=11
                     /translation="MNQVESIENEIRVWSFQNFGNGLALGLTRFMGKFLLALALFLIGR
                     FIIKKLGHILPKTPISAKIDPTVRNFFFRAIVLCLYLILGISCVSILGVPIASVITLLA
                     SAGVAVGLALQGSLSNLAGGIMLLLFRPFKVGNYIKSGTDEGTVQEVSIFYTVILSPDN
                     KRISIPNGSLMNANIINYSAERFRRVDLIYQLGRDEDVEKIKGYLEACIQDDELIRKYP
                     EPFVGLTAVGRDYLEFSVRLWVDTPSYWTLYNRINEKVAIKFAKENVLLPSTAIKNIQN
                     "
     PFAM_domain     20301..20882
                     /aSDomain="MS_channel"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00924.20"
                     /description="Mechanosensitive ion channel"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_250_0021"
                     /evalue="9.30E-42"
                     /label="ctg1_250"
                     /locus_tag="ctg1_250"
                     /protein_end="269"
                     /protein_start="75"
                     /score="143.0"
                     /tool="antismash"
                     /translation="IVLCLYLILGISCVSILGVPIASVITLLASAGVAVGLALQGSLSN
                     LAGGIMLLLFRPFKVGNYIKSGTDEGTVQEVSIFYTVILSPDNKRISIPNGSLMNANII
                     NYSAERFRRVDLIYQLGRDEDVEKIKGYLEACIQDDELIRKYPEPFVGLTAVGRDYLEF
                     SVRLWVDTPSYWTLYNRINEKVAIKFAKENV"
     CDS             20979..21551
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 96.7;
                     E-value: 2.1e-29)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_251"
                     /transl_table=11
                     /translation="MINVSMLVADFPGQEEIADELIFSLAKGNREALKIIYEKSINALY
                     AYVLSLTKNKYDTEDVLQETYVSIAENAASYHGGNKAMAWIFRVAKNFTLMHFRKEKNK
                     ESIHEVEEAVDAKYSFSFVENADHRMLLESAMEILEEEERQILFLHAVAGWKNREIAEY
                     LGKNLNTVLSKYQRSIKKLQEHLGKDE"
     aSDomain        21072..21536
                     /aSDomain="TIGR02937"
                     /aSTool="tigrfam"
                     /description="sigma70-ECF: RNA polymerase sigma factor,
                     sigma-70 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_251_0011"
                     /evalue="4.40E-23"
                     /identifier="TIGR02937"
                     /label="ctg1_251"
                     /locus_tag="ctg1_251"
                     /protein_end="186"
                     /protein_start="31"
                     /score="79.7"
                     /tool="antismash"
                     /translation="ALKIIYEKSINALYAYVLSLTKNKYDTEDVLQETYVSIAENAASY
                     HGGNKAMAWIFRVAKNFTLMHFRKEKNKESIHEVEEAVDAKYSFSFVENADHRMLLESA
                     MEILEEEERQILFLHAVAGWKNREIAEYLGKNLNTVLSKYQRSIKKLQEHL"
     PFAM_domain     21087..21284
                     /aSDomain="Sigma70_r2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04542.16"
                     /description="Sigma-70 region 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_251_0022"
                     /evalue="1.30E-09"
                     /label="ctg1_251"
                     /locus_tag="ctg1_251"
                     /protein_end="102"
                     /protein_start="36"
                     /score="37.8"
                     /tool="antismash"
                     /translation="YEKSINALYAYVLSLTKNKYDTEDVLQETYVSIAENAASYHGGNK
                     AMAWIFRVAKNFTLMHFRKEK"
     PFAM_domain     21363..21524
                     /aSDomain="Sigma70_r4_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08281.14"
                     /description="Sigma-70, region 4"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_251_0023"
                     /evalue="1.10E-12"
                     /label="ctg1_251"
                     /locus_tag="ctg1_251"
                     /protein_end="182"
                     /protein_start="128"
                     /score="47.4"
                     /tool="antismash"
                     /translation="RMLLESAMEILEEEERQILFLHAVAGWKNREIAEYLGKNLNTVLS
                     KYQRSIKKL"
ORIGIN
        1 actctgatta tcggtggagg aatggcattt accttcgtaa aggctatggg ctatgaaatc
       61 ggaaagtcct tagtggatga cgagaagctt tcctactgta aagaaatgct tgaaaaggga
      121 aagaaattag gctgtgaaat tctgcttcct gtggatgcgg tttgtgcggc atctttcccg
      181 gatcctattg atgatgccaa cttagcagta aagactgtgg atatttctga aattcctgca
      241 gatatgctgg gcttggatat cggaccgaag tctgcagagc tttttgccaa tgcggtgaag
      301 tctgcaaaga ctgtggtatg gaacggacct atgggcgttt ttgagaaccc tgtattggct
      361 aagggaacca ttgcagtagc aaaggctttg gcagagacag aggctactac cattatcggt
      421 ggtggagata gtgccgcagc ggtgaatatc ttgggcttcg gagataagat gactcatatt
      481 tccaccggcg gcggagcttc cttagagttc ctggagggaa aagagcttcc cggtgttgca
      541 gctgcaaata ataagtaaga agttctataa ataatcagat aaatccgtat gcatagaagt
      601 cagtatatac agatgtcatt aaggacagta gttagtaaat acagaaatca gtatatagat
      661 tattatgcat aagatagata gaaattgtag gaaataggtg agaagatgag aaagaaaatt
      721 attgcaggaa actggaagat gaatatgacc gtaacagagg ccaaggcttt atgcgataaa
      781 ctgcttccct tggtgaatac ggatgcggtg gacgtggttt tctgtgtacc ggctatcgac
      841 attgtacctg tagtggagaa gcttcagagc tccaagattt ccgttggagc ggagaatctt
      901 tactttgaag aggccggcgc ttacaccgga gaaatctccg ccaatatgct ggtggatgca
      961 ggagtaaagt atgttatcat gggacactcc gagcgtagag gatatttcca tgagacagat
     1021 gaggatatta acaagaaggc taagaaggct ttggaaaagg ggcttacccc tatcatttgc
     1081 tgtggagaaa gcttagagca gagagaaatg ggaatttact ttgagtggat ttccatgcag
     1141 attaaggcgg ctttccaggg aatttccgcg gaggatgccg gaaaatgcgt tatcgcttat
     1201 gaaccaatct gggccatcgg aaccggaaag actgcaacgg ctgagcaggc ggaagaggtt
     1261 tgtgcataca tccgtaaggt aatttgcgaa atctattccc aggcggtagg agagaagatt
     1321 cgtattcagt atggcggatc tatgaatgcc ggaaactgca aggagcttct gtccaagcca
     1381 aacattgatg gcggattaat cggcggtgca tcccttaaag aggagtttgc taagattgta
     1441 aactaccagg attaagaaga agtaccagaa ctaaaggagt accgtacgtt atgcgtacgg
     1501 tactctttaa atttagaagg attataaaga ggatttaacg aatcagaaat agtgggtagc
     1561 ctgttatgca gtataggtct aaaaaggggt aatctgagcc cgtgggttct tggcttttgt
     1621 cttttaaaag cttagaaccc ctacgtggcg aggttagcga gagcgtgccc cgttttagac
     1681 ctatactgca taaaggctat ttataaaact gattaaagtc tctttataat cctaaaattt
     1741 tctctttgga tttttcggaa accagcctct ttccactctc ttttcctgtt cgtataattc
     1801 atggatactc caaaagcagg agatgccgaa gatggccagg cttccggaga ggaatagaga
     1861 aggaagaaaa aggctggcta tacaagcgaa taaaccgatt aagaaaaaaa gccaggctat
     1921 tttcttacta aagtaatatt ccgcatatac cactatgggg tgaaatatcc ctatgcagag
     1981 aaaacacacc aagcctaaga gtaaaccttg aatactcata gtttaaaata ctcccgaagc
     2041 tctcgaagca gggtatccaa atccacctct gcccgttcac tcataatctt taccgtggct
     2101 ttcggcatca taatacgagc aagaggagtg tttaaggcct taaagcggtc acttaatcgg
     2161 aaaaggagag tctttacatt gggatctgct tccaaaatat cctttagcag ggtgtcttcg
     2221 ttgatttccg tcagcttgcc ggctgccaaa gtccctgcgc tttctttatt gcctacatct
     2281 tcagaagtct ttgagccttc cctcttgtct tcgtcttcag aagtctcctt gctttctccc
     2341 ttttcctgtt gctcccaggt tagaagagtt tgagagcctt gtaaggaacg gatatgggtg
     2401 cagtcctgca tcatttccag cacaccccgg aactttccgt tttcatcccg aaccgcatag
     2461 tagatgatgt aaataaagag gtccggctta ttaatccaaa actccgcctt gtcctgctct
     2521 ccggaacgga acttcttgat tatttcttca acgatatgta ccgaagcttt tggatgacag
     2581 tttttcacat ctctaccgat gacattttta cttctgggga aaactctgtg cttggtgtcg
     2641 gtatagaagc aaaccagttc attttcatct acataggaaa gatccaccgg catatgctgg
     2701 taaatcagat taatctgctc cagagtaagc tgaccggtag taacattcaa tttttcttct
     2761 ttattgttaa agccgtattt tcctagaaga ccggcaagct cttccgcaaa gccgggagca
     2821 gaggaaagac cggagagggg agaggtactc tgagaagcgg tatgggagac gttttgcttt
     2881 ggagattttt ccggctcaac ggtaatataa gcaaagccga tttcccggtc tccctcagcc
     2941 atatagcgaa actcttcgtc acttatcatc tccaaggaag tggggtagag gatattttcc
     3001 tccttgtcca tcaaatcccg aacatccgcc acaagctctg cctgctttcc gataaactcc
     3061 tcttccttat cctctaaaag aagcttgtag cactctgcaa tctcatcccg gataaagtca
     3121 tccagcgtcc acatggtggt ggtagggcgg gtaaagccct tcttttccaa aaccggatag
     3181 agctggtttt gttttctgga caaatgaatt ttgaatttca acaattcttc atatagttcc
     3241 agccattggt ttttaatgag gggatactgc accaaatcct ctacagaaaa cagtaattcc
     3301 ttcattttgg cattttccct acggtaacag gagataggat gattttccgg aagctcttga
     3361 tcctttgtga ctaaaacatc ctggaagacc tccagcatgg cctgaatatc ttccttaatg
     3421 cactcgtctt cggtttcctc caccatttcc tgctcgataa tggcaatttc atagggggcc
     3481 aggtgttgta ctctatcctt cagcgctttt ctggcttctt ccaaggaaat cttaccttca
     3541 tcataggcgg actttatttc gtgaacaatt tctaacttct tcccatcaat attttgaaaa
     3601 ttctctctca tcgcttcctc cttatgtaga ttttcaatct actaaacaat taaatcagaa
     3661 ttagacagct ttactagtct attgagttag aactatctaa ccaacactat cataacaaaa
     3721 acgatgagag aataacaatg aaaattccat atcaaattct aaagagattt tcagaagatt
     3781 tctctaacac attgtcactt tgtaaagggt atgagctctt ttaatatatg gggaaaaaat
     3841 ataaaaatta ttaatgatat tcataacgaa gattttattt attattctta aaaatagcaa
     3901 tatactgatt gggtagatat ggctaaccga tttaaataat aataattgaa acaggcgagt
     3961 tcgactaact tttctattca aatgatttct tatcattttt agaatatgcc ggcagagaaa
     4021 agcaaagaac taagcttcat ttttggataa accggaaagc atagtaaggg gcgttaagaa
     4081 aattaaacct ggacgtgagg ccgtaaatca cagtttatag aaagaggttt aaaatgaaga
     4141 agatgacgaa aggggttatt ctatcccttg cttttgtctt gcctacaatt ttggtgcagg
     4201 gaaaagcatt tgctgcagag actgcaaata ccggcgagtg gaaagcaatg aatggaaaat
     4261 ggttctatga gaaagaaggt aagccggtaa aggattggct tatggataag ggaaattggt
     4321 attatctttc tcaggactcc ggagagatgc ttctgggaag tcaagatatt aagggcgcta
     4381 actattattt tcaaaataaa aatgaggcgg tagaaggttc tatggcaaga ggctggcatc
     4441 aagacagtaa gggtgcctat cgcttttacg ataaccggga gggaagccct acagagggac
     4501 aggagcttag aggctggcaa tggattgacg gatattgcta ttattttgaa gaagaagaag
     4561 gcgagaaaaa gggaattctc ctgcaaaacg gcatgagcaa ggacggttat accgtaaatg
     4621 aagagggaca atggacggta aacggtgtag tgcagtttgt tgagggaaaa ggctttatca
     4681 caaaaaaatc cgatgtaaaa ggtgtttcca gaacgattga aaatacggaa gctcgtccgg
     4741 agagaacaag ttctacacgc agtcactccg gaagaagaag cagtggagca ggaagtaacg
     4801 gaagcggtaa tataaacagg aatggaagca atgccggagc aagcggaaat gcaggagctt
     4861 cctctagcgg agtgggtgag caagataaga aaaattccaa gactgaactg cctcaggaga
     4921 attctaaagc agaaaattct aaagtggaaa caggaaaaga aaatccggat aagaaggcgg
     4981 aatccttgct tgcagatggt gttttctacg gtacgggaac ttggtcaaga tactatgagc
     5041 aaagcggtcc ggatatcgta aaagtcagca ttaaagacgg caagattgca gaagttagca
     5101 atgtgaaata cacggaagat gacagctatc aggacaagac ctttaagatc tttgattatc
     5161 tcaaaggctt agaggatgta aaagaactgg agaaaaacct gaaggagaaa aagggcgaag
     5221 cctatgatgc ggtagcttct gcaacccagt ccacattggg cgaggtcagt gcagtggata
     5281 atgctcttgc ccgttccaga aagctgaaaa aagacaaaaa agaacaaaaa attgcctatt
     5341 ttgattttac aagaaagcca aatgccagag cagtagggga tagcttggat ctttctgaca
     5401 ccattcttga cctacatttt gcagacgtaa gcagacagga tgttccttat gcagactttg
     5461 caaagcatgg cattaccgtg gataaagaac agggaagccc cttaccggaa attggaacaa
     5521 cttttccggt atatttccaa aacgaagact ctttgattaa gctcccaagt tttattcagg
     5581 tgcaaaagga ttataggtgg gcttatgcgg atgagattcg cctgacctat gaaaatggag
     5641 aggtgaaaac ccttccaaca gataaagatc attttgttta ccgtgctgta gaaacgggga
     5701 aagacatcat caaggcggag ttgcttcggg gaggaaaggt cctgacggag ggagtgtatg
     5761 atgcaaatcg ctctgtttgg gatttccaat tagatgataa acagcttcca aaagactatg
     5821 atgcttggag atataaggat attcaattaa aagaagttat ggatgaagga aaaatccctg
     5881 cttccgtaga acttctttat gatggggagt atattctgga agacacaatc catctggaaa
     5941 aagaagccat tctgtccgga gaagttcttg aaaaggacgg ggatgtaaat cttgattatt
     6001 tcgatgaaat cgaaaaaaat ccagctttac tgcttggaga agcggagaat gaaaatgaaa
     6061 agactgtaaa agtggaacta cgctatattc ctgacaagac agagaaaaaa gtttccggag
     6121 agggaaactc tgaaaacggg gatggagaag aagagaaaaa tgctaccgta gaactaagtt
     6181 ttccggattt aatcattaaa gggaagacgg cgaagttaat tcttcgtctt cactatgttt
     6241 ctatcgagga ggaaggcgaa gatggagcag tggaaacaga gtaatgcgca tagcaatcct
     6301 cttttttaga atttattagc aatcagaaaa ataaatcgtt ttccggcagt atagtcctga
     6361 aaaaggggta gtctgagccc gtgggtactt gcgaaaaaca agagaaacgc agtttttcgc
     6421 ttagtatccc ttatgtaagg acaaactttt catcagaaaa gttgttctgt acgagaccaa
     6481 cttccgaagg aatttgcttt gcgaagcaaa gtgagcagtg gttaacaaaa ccactgctca
     6541 gtcaggcgaa gctagcgaga gcgtgcccca ctttcagacc tatactgtac ggaaaacgtt
     6601 tttgattatt ataaatctgt tttaaaaagg aagattacta aagctgaatt ccgtttttcc
     6661 gcccttctta tcgatgctga tgtcaaagaa tagttcattg gatagccttc catttccata
     6721 gaatatattc tcttcctcta ccttttgttg gaagggaagt tttttttcca gcagctttat
     6781 attgtcttcc atattatcaa tagtaaagaa gaactggtac tggaattgct ctatatttcc
     6841 ttctccatag tggaaaaagc tcatttcata aaggggtgta tccggaaaac tgctaagtgc
     6901 tttttcaata gcttcctggg aattgttcgg aagactttcg ctgtagggat acagaaaatt
     6961 ctcctcctga acatctgctt ttccgaaaag agaagatgtt ctggagcagt aaactggatg
     7021 aagaaagaga ggaagggaag agagtagcga aagaagaaat atcactatag tccccttacg
     7081 aaacagctca aatactgcca gtttcttggc gtaggaagcc aaaagtccca gccctccata
     7141 cagtaaggga aggactgtga aaaagaagca aagggacagt aggggggaag agggaagcaa
     7201 aagcttcgga tttttatagc tgtagagtaa gataggtaga agaaacagaa gaaattgtaa
     7261 gctgattccg aaaagaatca atggaaaaaa atgatgagaa aaaagcagtc ttttgggact
     7321 gcctttttct gttgcaagct tttggttctt ctgaaagagg gcgcctaaaa aggactttcc
     7381 gctcttattt ttattttctg tgaaatgtaa atccttagac atttgcttag atttcccatg
     7441 gcaggttttc cttaccgaag tgtccgtaag aagaaaccag attatagtct gtatttaaaa
     7501 gatttaagtt ggaaataata ccctttggcg taaggtcgta cttttcgatt acggaacgcc
     7561 aaaggtctcc cacattttca tgctcggtac cgaagcagtc cagataaacg gatacaggct
     7621 ccgccacacc gatagcataa gccagctgta cctcacatct gtcagtcttt cctgcggaaa
     7681 ccaggtcctt cgcaattttt ctggccatat aggctgcaga acggtctacc ttggaaggat
     7741 cctttccgga aaatgcgccg ccgccgtgat gagcagcgcc gccgtaggtg tcggcaataa
     7801 tcttacgtcc tgtaagaccg gaatctgcaa aggaggaacc gagaacaaaa cgtccggtgg
     7861 ggtttaccaa gatgcggaag tcggtattta aattcatttc cgcagcggtt tccaccatga
     7921 ttttctgaat aatctcccga acctgtgaca gggaaacgga ttcactgtgc tgagaagaaa
     7981 tcaggaaggt atcaatgcga ttttccttgt aatcatagct tacctgggcc ttagcatccg
     8041 gctttaaaat agaaaaggca ttttccagat taaaggcacg gagcttctgc aaagctctgg
     8101 tggataaaac atagggaata gggagcattt ccttggtttc attggtggca tacccgaaca
     8161 tcattccctg atctccggca ccgtcatggt ctacacccat ggcaatatcg ggagactgta
     8221 cggaaatcaa ctcttgaatc ttatagcgat ccaagtcctc caaaccgata ttctttaaca
     8281 cgtttcggca aagagtatcg tagtcggggg tgtggctgct ggtgatttct cccaaaatca
     8341 caatatcata gtctttaatg caacattctg cggcgattct tcccttggga tcgtgcttta
     8401 aaatgtctgt aacgatggca tcactgattt gatcgcaaat tttatccgga tgtccgttgg
     8461 aaacctgttc tgatgaaaat aacataaaaa taatcctttc tattttgtat acagagtggg
     8521 agaaagcttc gaaaagacat aaaaaaacca ttgggctcgc caatggtcga taatcttctt
     8581 attgatcgaa acaaatggtt cgctcaggtt agcaccttcc gtttccgggg ttgctgcggc
     8641 ttcttagctc ctatgtagct ccaccgactc tgaataagct atgaaatttt gttctgttat
     8701 actaacaaag agaagcgtaa aatgcaagga aaagttcggg agaagaatat aaaaaaataa
     8761 taaatttaag ttttctttac attccgggaa gaatgagata taagagaggg cacggctttg
     8821 ccgatataag ataaaaggta atgagaaaaa taatactgtc aaaaggaaag cgaacaataa
     8881 tagaggatag aggaagggat taaaatgttt aaagcgatag cattggattt ggatggaaca
     8941 ttgaccaatt cggaaaagaa ggtcagcgaa agaaacaaaa aagctttgca ggaagctgta
     9001 aaaaggggcg tcagcattat tctggcttcc ggaagaccta cctatggcat gtccgaggtg
     9061 tgggaggcct tagagctgga aaaattggga ggctatgttc tttcctataa cggaagtctc
     9121 tgtatggatt gtaagagcaa agaggttttg tttgagaaga cgattccccg gaagtattat
     9181 gagcctatcg ccaaggcagt aagagaggcg gatttaggtc tcctttccta tcaggggaag
     9241 gagattgtaa cagaacgacc ggaatttccc tatatggata gagaaagcac cattaataag
     9301 atgccctttc gaaaggtaga agattttcca aatgccttat cggaggaagt ttgtaaactt
     9361 ctggcattgg gagagcatga ggagctcctt cccttaaagg aaagactgga aaaggagtat
     9421 ggggaggaat taagtatctt cttttccgaa ccctttttcc tggaaatctg ccccctagga
     9481 gtagacaagg gagaatcctt aaaaagactt ttagagaaaa agggctggaa gagagaagag
     9541 ctgatggcct ttggagatgg aggaaatgac cttaccatgt tagaatatgc cggaaaaggc
     9601 attgccatgg ccaattccca aaagcatgtt ttagaaatag ctgacgaaat cacactcagc
     9661 aatgatgaag acggagtagc agtaatggtg gagaagtaca ttttgagcaa tatataagaa
     9721 atagtattga tacatgttat ttttgcatat tcatttaggg tgaaatcaaa tttgtaataa
     9781 tacgtataca gctttttatg caaaataggt ctgaaaaagg ggtaatctga gcccgcgggt
     9841 acttgcgaaa aacaagagaa gcgcagtttt tcgcttagta tcccctgcga ggcgatgtta
     9901 gcgagagcgt gccccaattt cagacctatt ctgcctaaaa aagcgtaaaa attataattc
     9961 aacacactat ttccttaaat actttgcgca atgggcttcc ttacccctgc tccatcaagg
    10021 attcctccac cttcatcata atggcgcatt ccattctctt tcggaagagc ttacagccat
    10081 actcataggt accggcaata tctccggtgg agtggtaggc atttgcggca cagcctccgg
    10141 cgcaatatag ctttgcccag cattttccgc agtcttctct ggtatagaca ttggtgtttc
    10201 ggaattcttc tctagcttct tccttggtga taccgttcca aatatctccc agcttatatt
    10261 ccttgtcgga gacgaactgg tggcaggggt atagctcccc ctgggcggaa accgccatat
    10321 actcggttcc ggaaccgcag ccggagattc tcttataaat gcaggggcct ctgtccaaat
    10381 ccaccatata atggtagaag gttacaggat ctcccgcctt ttttctgcga agcaggtcca
    10441 gtgccagctt ttcatattgc tcatagagga tgggcaaatc ttcctcggtt agggcggagg
    10501 gctctcccgg ctttaaaacc accggttcca tggacagctc tttaaagccc agctcatcag
    10561 ccatgtgggc aatatcttcc gtaaaatccg tattaaaatg ggagaaggtt cctctcatgt
    10621 agtactcctt gtccccccgt ttttccacaa aacgctggaa cttggggacg atttgatcgt
    10681 agcttccctt tccctttcgg tctacacgaa aacggtcatt gacttccttt cgtccatcca
    10741 gacttaaaac cacattatga cattcttcat ttgcccaatc catgatttct tccgtgagtc
    10801 ctacaccgtt ggtggttagg gtgaaacgga agttctttcc cttttccttc tcgatggagc
    10861 gggcataggc caccagatcc ttacaaacct ggaagttcac caagggctct ccaccaaaga
    10921 agtccacctc taaatttcgg cgggtgccgg aattttcaat gaggaaatcc agggctcttt
    10981 ttccggtttc aaagctcata agccctgact ctccgtgata atgcccttgg gaggcaaagc
    11041 agtaggagca agctaagtta cagctgtggg ctaccaaaag gcaaagagcc ttgatcacat
    11101 ttccgctgtg ggattttagc tttccggcta aaggcgcata gttgtcttta gtaaagagct
    11161 ttttgctttc gattaattca tctatatccg aaaagcagtc tagaaagtcc tgctctgtac
    11221 tctccggaaa ttccacttta agcttttgga gcacttcctc tctggaaagt cctttttcca
    11281 aatagccgat ggcagcataa gccataggat ccgtaacatg gatgcttccg ctgtatacat
    11341 ccaaaacaat gtgtcgtccg ttcatcaaat actggtgaat catttaccct tccttctata
    11401 aaacaaatgt atacataaaa ttaatgtata aactaaatca gtataaataa aatcaatgta
    11461 taaagataat caatgcataa agatagtgtt tcaatcaatg gcgaaaaaaa agaactgtgt
    11521 ctgcacacag ctccttcttc tgagaaatcc ttagttgttt tcgttctcgc agttttgatt
    11581 tgcgataccg cagctggtct tacaagcaga ttgacaagat gtttgacact ctccacatcc
    11641 gccgtgctca acgctcttct ctaaatctct ggtgcttaag gtaataatgt gcttcatttc
    11701 ctatccctct ttctcctgaa tgctttttca agcaatttat ttactcctgc attttacctg
    11761 ttacgctaaa actttgtcaa gattggaaag ggattttctt tccctttaga ggaaaatatg
    11821 gtagtcttag agggacaaaa atgaatttgc ttaccataaa ggagtgagtc tatgggattg
    11881 ataaaagcag gtaaagaagc gggaatttcc gttttagcag atcagtggag agagtatttc
    11941 tattgttctt ccttagacaa tgataccctc atgaccaagg ggcataagag aattggacaa
    12001 aacagttcca atactcgagc ttcagacaat attatttcca acggtgctgt cattgccgta
    12061 aacgaaggac agtgtatgct gattgtggag cagggcgcca tcgtggagct gtctgcagag
    12121 gcaggagagt ttgttttcga ttcctccacg gaacccagta ttttctacgg ctcactgggt
    12181 gaaagcgtag tagaaagctt taagaccttt atgaagcgtt tgagcttcgg cggagacacg
    12241 gcaaaggatc aacgcattta tttcattaat cttaaggata ttgtgggcaa taaatacggt
    12301 accgtaaacc ccattccttt tagagcggtg gatcccaaca ttaatctgga catagagatt
    12361 tcccttcgct gtcacggaga atatgcttat aagattacgg accctgtact cttctatagg
    12421 aatcttgcgg gcaatgtaga gggagattat aagaaggaag aggtggagtc tcagttaaag
    12481 tctgaacttt taaccaattt acagcctgct ttttcccgta tttccgaaca gggaatccgc
    12541 taccacagca ttcttagcca tacggatgat attgctcatg ctttaaatga tattctttcc
    12601 agtacctggg gaggacatta cggtattaag attaccagct tcggtatcag ctccatcaag
    12661 gcgccggaag aagatgagaa gatgattaag gaaatgcaga gagatgctgt tttccgtgat
    12721 cccagcatgg ctgcggctta tctttccaag gctcagggag atgctatgaa gcttgcagca
    12781 ggaaataccg ctacaggacc aatgatggcc tttgcgggaa tgaatatggc aaatcagacc
    12841 ggtggtttca atgcctccga gcttttctcc atgggggcta agcagggcaa tgcgcaggcg
    12901 ggacaaaata ccgctaatca ggcaaatgca ggagctcagg gaagcatctt tggacaggta
    12961 agtgttccta tgcaagaaac tgcaaacggt gccgtaccga ctgcagaagc aggcacagcg
    13021 gaggattgga cctgcgcaaa atgcggacat acccataata ccgggaagtt ctgctctgaa
    13081 tgtggagagg ctagagcgga taaatggaat tgtccggagt gcggacatac cggcaatgta
    13141 ggtaaattct gtccggagtg tggacataaa agataaaata tagaccggac tgtgaagaag
    13201 aaagggcaga atagagactt tctttttcac agtttttcta tatagaaaca gctatagggt
    13261 aaaattcttg acttatgttc ttaaggatgg aggacgatat ggataaagag ttactgggct
    13321 ggctttctcc caagggggat ttcttcccta cagactgggg aaagcattgt atggaagcgg
    13381 aaagaatttt aatgaaatta gggctttatg aggaattttc aaaacaaagc ctattcaatg
    13441 ccggagattt tttaagcgga agaggctatg tgcttttgca taatcccagt aagaaaaaac
    13501 tgatggctac agctctttgt ccccttagca aggcgcaaag aaattttctt tacggatatt
    13561 ttttggagtt ggggaaaagt aaggaagcaa aatactatct ggaggaggct ttctaaacat
    13621 ttttatgaaa gccttttaga tggttttttg tctttacgaa tgaaaaaaag aagagtatga
    13681 taggcactta atcttatgtg acttaaagga ggaagaagca tggcactcgt aattccaaag
    13741 gactattccc caaggctcag tgttcgggaa acccaagagg caattaaata tatcagagat
    13801 actttccaaa aggagtttgg aaaggagatg aatttatcca gaatttccgc tccgcttttt
    13861 gtggagaaga gctccggatt aaatgataac ttaaacggtg tggaaagacc ggtgtccttt
    13921 gatgtgccat ggaaaaaaga ggaagtggtg gaggttgtcc agtctctggc aaagtggaag
    13981 aggattgctt taaagcgtta taatttccaa gtgggagaag gcctctacac caatatgaat
    14041 gccattcgcc gagatgaaga attggataat ctgcatagct gctatgtaga ccagtgggac
    14101 tgggaaagag tcatcggaaa agacgaaaga acggaagagg tactacagaa cacggtaaga
    14161 gacatttttc gtattatcaa gcatatggag catcaggttt ggtataagta tccggatgcg
    14221 gtgaagaagc tgccggagga gatttacttt attgactctg aggaactgct taaaagatat
    14281 ccgaatctca gtccgaagga aagagaaaat gccatcacca aagagcacgg ctgtgtattt
    14341 attcaaagaa tcggagataa gctcagtaac ggggaacccc atgacggcag agctccggac
    14401 tatgatgatt ggagcttaaa cggagacatc ctcttctggt ttgaaacctt aaattgtgct
    14461 ctggagattt cctccatggg aatccgcgtg gatgagaagg ctttagagag acagctcaag
    14521 ctatcccata atgaagacag ggcaaagctc ccttaccata agatgctttt ggaaggaaag
    14581 ctcccccaga ccatcggagg cggaatcgga cagagcagac tttgtatgtt gcttttggac
    14641 cgcgctcatg tgggagaagt acaggcatcc atctggccgg aggagatgcg aaagctttgc
    14701 gaggagaata atattttcct tttatagtac gtttgaaaat tatatataag agagtataga
    14761 aatagtagaa gcgaagacac tttttgtgtt ttcgcttttc tgcattatag ctctaaaaca
    14821 ggggcacgct ctcgctaact tcggcacgta gctgtactaa gctaaaagct acacttcgtt
    14881 tgcttttcgc aagtacagac ggcctcagat tacccctgtt tcagactata aatgcagaaa
    14941 agctggtaaa atgctcatcc accgttcgga gccggtatct tttgtaaaca atagcttatt
    15001 cactttatat ataaattgat atttggcaaa ggtactataa aagtcaaata tttattcctg
    15061 ccgcctgctt ggctaagagg tcggctcttt cattaaagta atccccgcta tgggcttgaa
    15121 ccttatggaa agaaattatc agcttttttt ggaattccag cattttttct ctatattcta
    15181 tagttttttc tttgttgcat ttccattctc cctttgccca ggaggcgatg ccttggtaat
    15241 cgtggaatat ggcgatggag gagtagcctt tttccacagc caaggaagct gcttttaagg
    15301 ctcccaggat ttctccggaa acatttctca tgctttggta gctttcttcc cggcctgaat
    15361 caaagtattc ttctatagtt ccattctttt caatgaaaac cacgccgtat ccgtagactc
    15421 cattgtcttt ttcaaagctt ccgtccacat aggcaatgca gtctgtctta gtgctctgaa
    15481 aaagctcttc tatggccgaa agagaaccgt cttgtaaggg gagaagagtt gccttccctt
    15541 tttctttccg ggaagaaggc gtttttgaac caaaactaat agagctcatg tcggagccgt
    15601 atggctttga attgccgcta ccgttcatat aggcttctgc ctcttccctt gttttccact
    15661 ttttgaattt ggcactggga taagccttta cctgtttttc gcattctgcc cagctactgt
    15721 atattcccgg attttttccg atttttaccg cgtaataata agccatgata gacattccct
    15781 ttcttcctct ttatactggt ggaggagaaa acattggatt ttcaagatta ttttttcaaa
    15841 ggaaagctga gatattgaaa ttctactagc tgagatatag aaatccaact agctgagata
    15901 tagaaatcca aacagcagat ttcctttgaa tgcatagtga atatacacta aaagctttta
    15961 aaaagtatat agaggagttg aaaatgggaa agaaaataaa ggcagtactt tttgatttgg
    16021 atggaacttt ggtcaatacc ttagccagcc taaaaagaaa tatggatttg accatggagc
    16081 atttttcttt ggagggtgtc agtctggagg aaaccaagaa gtttgtgggt gtggggacca
    16141 agaaatttgt ggaaagatgc ctggaaaaga atgcgcagat ttggtatgag aaggcggaaa
    16201 aatgggaagc aaaggatgag gagaaggcca tggacttgga ccttaagggg gatgaggtca
    16261 tggagcttta tgaagaggcc tatgaatatt atcgctccat ttttccggat aattgtacct
    16321 atgaggcgga accctacccc ggtattcatg cctgcctgaa acgcttggag gaaaagggga
    16381 ttttcagagt ttgtattacc aataaaccca aggaagaggc gtccattatt ttggacaagg
    16441 tatttgcttc tgacagcttt actctggtac tgggagataa tggaaagatt cctttaaaac
    16501 cgaatccgga tatgcttctt acggtttgca aggaactggg gatttcttcg gaggaggctg
    16561 tcatggtggg agataccaag acggacttgg atgcggcgaa aaatgcgggt atgctcagca
    16621 ttggctgtct ttatggattt cgggataaaa aggagcttga ggagcatggg gcaaagtacc
    16681 ttgtgaagga cggagaagag ctatggcagg ttttggagga gaattttttg gaaaaatgat
    16741 ttaatatttc taaagaaagt taagtatagc taactttata ccgcggttat attgacaagg
    16801 tggaagatta tcgtaaaata gcgcttgtat ccatagaaaa atgtattcat cccaaaggag
    16861 gattttatga caaagattga tattatttca ggttttttag gagccggaaa aactacattt
    16921 atacagaaat tactttccga tgctttaaag ggggaaaatg ttgttcttat cgagaatgag
    16981 ttcggtgaga ttggtgtgga cagcggcttt ttaaagaatg cgggaattga aattcgggaa
    17041 atgaaccagg gctgcatttg ttgttcttta gtgggagact ttgaaagctc cttaaaggaa
    17101 gttattgaac agtaccatcc tgatcgtatt ctgattgagc cttccggagt tggaaagctt
    17161 tccgatattt tatcggctgt aaagaccgtt tccgagaatc tggatgtaaa gctggatgga
    17221 gccgtaaccg tagtggacgc tacaaaggca aagctgtaca acaagaattt cggtgagttt
    17281 tttgatgacc agattcgttt tgccacttcc gttgtactgt ccagaatgga tattgcttcc
    17341 ggagagaagg ctcaggaggc cgtaaatatt gttcgtggca tcaatcctca tgctaacctg
    17401 attaccacag cccttacgga gttaagcgga gaaaagcttc tggaaatcat cgggaaggaa
    17461 gagaatctgg aagaggagct tttggcagaa gtaaaggcga aagccgctca tcaccatgag
    17521 catcatcatg accacgagca tcatcatgaa catcaccatg agcacgggga gtcctgtggt
    17581 tgcggatgcc atgatgagga agagcatcat caccatcacg agcatgatga gtcctgcggc
    17641 tgtggttgcc atgatgagga acatgagcat catcaccatc atgagcatga tgagtcctgc
    17701 ggctgtggct gccatgatga ggaacatgag catcatcacc atcatgagca tggagagtcc
    17761 tgcggttgtg gatgtcatga tgaagaagag catgagcatc atcatcacca tcatcatgaa
    17821 ggctgcgctt gcggtcatga ccatgatgcg gatgaaattt ttgacagcat cggtttggaa
    17881 gtatttaaga aggtagacag aaatcatttg gcagagattt tagaggaaat ggctgaaggc
    17941 tgtgcttacg gcggtattgt ccgtgcaaag ggtatgctgg cttgcacaga cggcacttgg
    18001 gtaaactttg atttggtgcc ggaacaggtg gaaatccgtg aggccggtcc tgaaaatatc
    18061 ggaaagttcg tggtcatcgg aactgagttg aaaaaggaca agattaaggc tttgtttaac
    18121 gactaatttt aaaatttaaa aaaagaattc tctgaaaagg aacaggttta ttttcctttt
    18181 cggagaagaa agcatagaac ggaaggagag tagaatggga gaacagtggg aagcggaggg
    18241 agaaggcatt cctgtctttt tgattaacgg atttttagag gtaggaaaaa gcagcttcat
    18301 tcaatttacc atggagcagg aatattttca gaccgagggc aataccctcc ttcttctttg
    18361 tgaggatggg gaagtggaat atgaccctat taagctggca gcacatcata caacgccggt
    18421 gtatatggaa aatattactg attttcagga agataaattg cagtctctgg caagacagta
    18481 taaggcggag agagtcttaa tcgagtggaa cgggatgtgg aaccaggatg atttatacgg
    18541 cggtcccatg agtgaagagg tactggcaaa acagcaaaat cgtgagccga agtatcatgt
    18601 gtccatgccg aagaactggt ttttatatca ggtgattacg attttagacg gttccagcct
    18661 aaagatctat ctttccaata tgcgttcttt cctggggcag atgcttcgtc atgcggagct
    18721 gtgcatcgtg aatcgttgcg ataatctgtc caatgaagaa ttagtggatt atcgtagaaa
    18781 gattcgggca atggggcaga atgccatgat tttactggag gataaaaatg gagaaattcc
    18841 ccagaccgct cttccggaag acctgcccta cgatcttgga caggatgcca ttactttagc
    18901 agatgaagat tatggtacct ggttcttgga ctgcatggag aacccggagc gctatctgaa
    18961 taaagaaatc acattttccg cgatgatttt aaaacgaaaa aatatgccgg agaatgaatt
    19021 tgttccggga cgtatggcga tgacctgttg tgcggaggat atgaccttcc tgggctttat
    19081 ctgtaaggga gacaagaagt taattgctcc cttttcaaca agagactggg caaagctcac
    19141 tgcaaaggtg aagctggaga aacgggaaga atatcatggt ataggaccgg ttttacattt
    19201 ggaaaagatt gccagaaccg gagaaatcaa ggaacctgtg aatttctaac gatttcttat
    19261 agaaggataa acgatatttt tttagaaata agtaagaaag ccttgcgaaa ttatattatt
    19321 tttgtatact aggagtgtta atttaacaag ggcaggattt gtatggatgc aagatgccct
    19381 acaacttaaa ggaggactta ctatgtcata tttacagatc tttgcactat taggagcatt
    19441 tttaatcccg tttatcttgc tttggctgat ttgctacggc ttggaggctt acgctcttta
    19501 taccctggct aagaataacg gtcaggagga taaggcaatt ttagccttta tcccctacgt
    19561 aaatcgtgga ctctatgctt attttgcagg tgaccaggag atgttcggta atcaggttcc
    19621 cacgattgcc agtgctgcaa tcatgggtgt gcttcccctt cttggtggat ttgttggcgg
    19681 cgccctttgg ggattggttg gcattatttt taccatcgta gtgattattg tttctttcta
    19741 caattataaa gccgtatacg gaaagatgag cagtgtttcc gattctactc ttttcggtgt
    19801 tttggctgcc gtaatttccc tttgccgtgt aatcttcatt ttccttcaca gaaatgatat
    19861 tctggtagag gacggagata tcgtagagta atatttcttt tcagcaagct atagcagtgt
    19921 tataccggct ccaaaagtta gacccaagaa tctaaccttg gaagccggta tttttataaa
    19981 tatttttaca gccaaagtag agccggggat attgctccgg tatgattttt aggaaaaagt
    20041 tttatccatc tacagtggta gggacgggag ataatatgaa tcaggtagaa agtattgaaa
    20101 atgaaattcg ggtctggagc ttccaaaatt ttggaaacgg cttagctctg gggcttaccc
    20161 gttttatggg gaaattttta ttggcgctgg cattgttttt gattggtcga tttatcatta
    20221 aaaagctggg acatattctt ccgaaaaccc ctatttcagc taagatcgat cctacggttc
    20281 ggaatttttt ctttcgagca atcgtacttt gtctgtatct gattttagga atcagctgtg
    20341 tcagcattct gggggttccc attgcttccg tcatcactct tttggcttct gccggtgtgg
    20401 cggtaggtct ggccttacag ggctccctat ctaaccttgc gggaggcatt atgcttttgc
    20461 tgtttcgccc ctttaaggtg gggaattata tcaaaagcgg tacggatgaa ggtacggtgc
    20521 aggaggtgag tatcttctat actgttattc tttctccgga taacaagcgt atttccatcc
    20581 ccaacggcag cctgatgaat gccaatatca ttaattacag tgcggagcgt ttccggagag
    20641 tggatttgat ttaccagctt ggtcgggatg aggatgtaga aaagattaag ggatatttgg
    20701 aggcttgtat tcaggacgat gagctgatcc gaaaatatcc tgagcccttc gtaggactta
    20761 ccgcggtagg aagagattat ttggaattca gtgttcgtct ttgggtggat actccatctt
    20821 actggaccct gtataaccga attaatgaga aagttgccat caaattcgct aaagaaaatg
    20881 tgcttttgcc cagcacggct attaaaaaca tacaaaattg attttctttg caataaaatg
    20941 ccctctctat gcattgtact tatgaaagga cgaaaaacat gatcaatgtg agtatgctgg
    21001 ttgcggattt tcccgggcag gaagaaatag cggatgaact gattttctcc ctggcaaagg
    21061 gaaaccggga agcgctaaaa atcatatatg agaaaagcat caatgcattg tatgcctacg
    21121 ttctttcatt aacgaaaaat aagtatgaca cagaggatgt tttgcaggaa acctatgtaa
    21181 gcattgcaga aaatgcagct tcctatcatg ggggaaataa ggcgatggca tggatattcc
    21241 gagttgccaa gaatttcacc ctgatgcatt tccgaaaaga gaagaacaaa gaaagtattc
    21301 atgaagtgga agaggcggtg gacgccaaat attccttttc cttcgtagaa aatgcagacc
    21361 acagaatgct tttggaatcc gccatggaaa tattggagga agaagaacga cagattctat
    21421 ttcttcatgc cgtggcaggc tggaagaatc gggaaattgc ggagtattta ggaaaaaact
    21481 taaatacggt tttatccaaa taccagagga gcattaagaa gctgcaggag catttaggaa
    21541 aggatgagta agatgaagca ggaaaatatg gaaaaagagc ttcaagaggc tgttcaaaat
    21601 cttatcccca atgacttatt tactaggatt accgcagaac tggattccaa ggaagagggt
    21661 gcaaagatgg aaaaagtgct ggtaagtaga atcgaaa
//
