Select genomic region:
Overview
101.1
134.1
155.1
159.1
193.1
196.1

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_AFGF01000126 (original name was: NZ_AFGF01000126.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 101.1 | cyclic-lactone-autoinducer | 69,110 | 89,784 |

NZ_AFGF01000081 (original name was: NZ_AFGF01000081.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 134.1 | NRPS | 1 | 25,657 | bacillibactin | NRP | 30%

NZ_AFGF01000054 (original name was: NZ_AFGF01000054.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 155.1 | RRE-containing | 40,141 | 59,655 |

NZ_AFGF01000050 (original name was: NZ_AFGF01000050.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 159.1 | hserlactone | 36,677 | 57,423 |

NZ_AFGF01000012 (original name was: NZ_AFGF01000012.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 193.1 | NRPS | 1 | 61,407 | paenibacterin | NRP | 60%

NZ_AFGF01000007 (original name was: NZ_AFGF01000007.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 196.1 | T3PKS | 7,828 | 48,871 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 101.1 | cyclic-lactone-autoinducer | 69,110 | 89,784 |
Region 134.1 | NRPS | 1 | 25,657 | bacillibactin | NRP | 30%
Region 155.1 | RRE-containing | 40,141 | 59,655 |
Region 159.1 | hserlactone | 36,677 | 57,423 |
Region 193.1 | NRPS | 1 | 61,407 | paenibacterin | NRP | 60%
Region 196.1 | T3PKS | 7,828 | 48,871 |

No secondary metabolite regions were found in these records:
  NZ_AFGF01000296 (original name was: NZ_AFGF01000296.1)
  NZ_AFGF01000295 (original name was: NZ_AFGF01000295.1)
  NZ_AFGF01000294 (original name was: NZ_AFGF01000294.1)
  NZ_AFGF01000292 (original name was: NZ_AFGF01000292.1)
  NZ_AFGF01000290 (original name was: NZ_AFGF01000290.1)
  NZ_AFGF01000289 (original name was: NZ_AFGF01000289.1)
  NZ_AFGF01000288 (original name was: NZ_AFGF01000288.1)
  NZ_AFGF01000287 (original name was: NZ_AFGF01000287.1)
  NZ_AFGF01000283 (original name was: NZ_AFGF01000283.1)
  NZ_AFGF01000282 (original name was: NZ_AFGF01000282.1)
  NZ_AFGF01000280 (original name was: NZ_AFGF01000280.1)
  NZ_AFGF01000279 (original name was: NZ_AFGF01000279.1)
  NZ_AFGF01000278 (original name was: NZ_AFGF01000278.1)
  NZ_AFGF01000276 (original name was: NZ_AFGF01000276.1)
  NZ_AFGF01000270 (original name was: NZ_AFGF01000270.1)
  NZ_AFGF01000269 (original name was: NZ_AFGF01000269.1)
  NZ_AFGF01000266 (original name was: NZ_AFGF01000266.1)
  NZ_AFGF01000263 (original name was: NZ_AFGF01000263.1)
  NZ_AFGF01000260 (original name was: NZ_AFGF01000260.1)
  NZ_AFGF01000259 (original name was: NZ_AFGF01000259.1)
  NZ_AFGF01000258 (original name was: NZ_AFGF01000258.1)
  NZ_AFGF01000257 (original name was: NZ_AFGF01000257.1)
  NZ_AFGF01000254 (original name was: NZ_AFGF01000254.1)
  NZ_AFGF01000251 (original name was: NZ_AFGF01000251.1)
  NZ_AFGF01000246 (original name was: NZ_AFGF01000246.1)
  NZ_AFGF01000244 (original name was: NZ_AFGF01000244.1)
  NZ_AFGF01000243 (original name was: NZ_AFGF01000243.1)
  NZ_AFGF01000241 (original name was: NZ_AFGF01000241.1)
  NZ_AFGF01000240 (original name was: NZ_AFGF01000240.1)
  NZ_AFGF01000238 (original name was: NZ_AFGF01000238.1)
  NZ_AFGF01000237 (original name was: NZ_AFGF01000237.1)
  NZ_AFGF01000234 (original name was: NZ_AFGF01000234.1)
  NZ_AFGF01000232 (original name was: NZ_AFGF01000232.1)
  NZ_AFGF01000231 (original name was: NZ_AFGF01000231.1)
  NZ_AFGF01000230 (original name was: NZ_AFGF01000230.1)
  NZ_AFGF01000228 (original name was: NZ_AFGF01000228.1)
  NZ_AFGF01000226 (original name was: NZ_AFGF01000226.1)
  NZ_AFGF01000225 (original name was: NZ_AFGF01000225.1)
  NZ_AFGF01000224 (original name was: NZ_AFGF01000224.1)
  NZ_AFGF01000222 (original name was: NZ_AFGF01000222.1)
  NZ_AFGF01000221 (original name was: NZ_AFGF01000221.1)
  NZ_AFGF01000220 (original name was: NZ_AFGF01000220.1)
  NZ_AFGF01000219 (original name was: NZ_AFGF01000219.1)
  NZ_AFGF01000217 (original name was: NZ_AFGF01000217.1)
  NZ_AFGF01000215 (original name was: NZ_AFGF01000215.1)
  NZ_AFGF01000214 (original name was: NZ_AFGF01000214.1)
  NZ_AFGF01000212 (original name was: NZ_AFGF01000212.1)
  NZ_AFGF01000211 (original name was: NZ_AFGF01000211.1)
  NZ_AFGF01000209 (original name was: NZ_AFGF01000209.1)
  NZ_AFGF01000208 (original name was: NZ_AFGF01000208.1)
  NZ_AFGF01000206 (original name was: NZ_AFGF01000206.1)
  NZ_AFGF01000205 (original name was: NZ_AFGF01000205.1)
  NZ_AFGF01000204 (original name was: NZ_AFGF01000204.1)
  NZ_AFGF01000203 (original name was: NZ_AFGF01000203.1)
  NZ_AFGF01000202 (original name was: NZ_AFGF01000202.1)
  NZ_AFGF01000201 (original name was: NZ_AFGF01000201.1)
  NZ_AFGF01000198 (original name was: NZ_AFGF01000198.1)
  NZ_AFGF01000197 (original name was: NZ_AFGF01000197.1)
  NZ_AFGF01000196 (original name was: NZ_AFGF01000196.1)
  NZ_AFGF01000194 (original name was: NZ_AFGF01000194.1)
  NZ_AFGF01000193 (original name was: NZ_AFGF01000193.1)
  NZ_AFGF01000192 (original name was: NZ_AFGF01000192.1)
  NZ_AFGF01000191 (original name was: NZ_AFGF01000191.1)
  NZ_AFGF01000190 (original name was: NZ_AFGF01000190.1)
  NZ_AFGF01000186 (original name was: NZ_AFGF01000186.1)
  NZ_AFGF01000185 (original name was: NZ_AFGF01000185.1)
  NZ_AFGF01000183 (original name was: NZ_AFGF01000183.1)
  NZ_AFGF01000182 (original name was: NZ_AFGF01000182.1)
  NZ_AFGF01000181 (original name was: NZ_AFGF01000181.1)
  NZ_AFGF01000178 (original name was: NZ_AFGF01000178.1)
  NZ_AFGF01000174 (original name was: NZ_AFGF01000174.1)
  NZ_AFGF01000173 (original name was: NZ_AFGF01000173.1)
  NZ_AFGF01000172 (original name was: NZ_AFGF01000172.1)
  NZ_AFGF01000171 (original name was: NZ_AFGF01000171.1)
  NZ_AFGF01000170 (original name was: NZ_AFGF01000170.1)
  NZ_AFGF01000169 (original name was: NZ_AFGF01000169.1)
  NZ_AFGF01000168 (original name was: NZ_AFGF01000168.1)
  NZ_AFGF01000166 (original name was: NZ_AFGF01000166.1)
  NZ_AFGF01000164 (original name was: NZ_AFGF01000164.1)
  NZ_AFGF01000163 (original name was: NZ_AFGF01000163.1)
  NZ_AFGF01000162 (original name was: NZ_AFGF01000162.1)
  NZ_AFGF01000160 (original name was: NZ_AFGF01000160.1)
  NZ_AFGF01000159 (original name was: NZ_AFGF01000159.1)
  NZ_AFGF01000158 (original name was: NZ_AFGF01000158.1)
  NZ_AFGF01000157 (original name was: NZ_AFGF01000157.1)
  NZ_AFGF01000156 (original name was: NZ_AFGF01000156.1)
  NZ_AFGF01000155 (original name was: NZ_AFGF01000155.1)
  NZ_AFGF01000152 (original name was: NZ_AFGF01000152.1)
  NZ_AFGF01000151 (original name was: NZ_AFGF01000151.1)
  NZ_AFGF01000150 (original name was: NZ_AFGF01000150.1)
  NZ_AFGF01000147 (original name was: NZ_AFGF01000147.1)
  NZ_AFGF01000144 (original name was: NZ_AFGF01000144.1)
  NZ_AFGF01000143 (original name was: NZ_AFGF01000143.1)
  NZ_AFGF01000141 (original name was: NZ_AFGF01000141.1)
  NZ_AFGF01000139 (original name was: NZ_AFGF01000139.1)
  NZ_AFGF01000136 (original name was: NZ_AFGF01000136.1)
  NZ_AFGF01000135 (original name was: NZ_AFGF01000135.1)
  NZ_AFGF01000133 (original name was: NZ_AFGF01000133.1)
  NZ_AFGF01000129 (original name was: NZ_AFGF01000129.1)
  NZ_AFGF01000128 (original name was: NZ_AFGF01000128.1)
  NZ_AFGF01000125 (original name was: NZ_AFGF01000125.1)
  NZ_AFGF01000124 (original name was: NZ_AFGF01000124.1)
  NZ_AFGF01000122 (original name was: NZ_AFGF01000122.1)
  NZ_AFGF01000121 (original name was: NZ_AFGF01000121.1)
  NZ_AFGF01000119 (original name was: NZ_AFGF01000119.1)
  NZ_AFGF01000118 (original name was: NZ_AFGF01000118.1)
  NZ_AFGF01000116 (original name was: NZ_AFGF01000116.1)
  NZ_AFGF01000115 (original name was: NZ_AFGF01000115.1)
  NZ_AFGF01000113 (original name was: NZ_AFGF01000113.1)
  NZ_AFGF01000110 (original name was: NZ_AFGF01000110.1)
  NZ_AFGF01000107 (original name was: NZ_AFGF01000107.1)
  NZ_AFGF01000106 (original name was: NZ_AFGF01000106.1)
  NZ_AFGF01000102 (original name was: NZ_AFGF01000102.1)
  NZ_AFGF01000101 (original name was: NZ_AFGF01000101.1)
  NZ_AFGF01000099 (original name was: NZ_AFGF01000099.1)
  NZ_AFGF01000098 (original name was: NZ_AFGF01000098.1)
  NZ_AFGF01000097 (original name was: NZ_AFGF01000097.1)
  NZ_AFGF01000096 (original name was: NZ_AFGF01000096.1)
  NZ_AFGF01000095 (original name was: NZ_AFGF01000095.1)
  NZ_AFGF01000094 (original name was: NZ_AFGF01000094.1)
  NZ_AFGF01000093 (original name was: NZ_AFGF01000093.1)
  NZ_AFGF01000092 (original name was: NZ_AFGF01000092.1)
  NZ_AFGF01000091 (original name was: NZ_AFGF01000091.1)
  NZ_AFGF01000090 (original name was: NZ_AFGF01000090.1)
  NZ_AFGF01000089 (original name was: NZ_AFGF01000089.1)
  NZ_AFGF01000088 (original name was: NZ_AFGF01000088.1)
  NZ_AFGF01000087 (original name was: NZ_AFGF01000087.1)
  NZ_AFGF01000086 (original name was: NZ_AFGF01000086.1)
  NZ_AFGF01000085 (original name was: NZ_AFGF01000085.1)
  NZ_AFGF01000084 (original name was: NZ_AFGF01000084.1)
  NZ_AFGF01000083 (original name was: NZ_AFGF01000083.1)
  NZ_AFGF01000082 (original name was: NZ_AFGF01000082.1)
  NZ_AFGF01000079 (original name was: NZ_AFGF01000079.1)
  NZ_AFGF01000078 (original name was: NZ_AFGF01000078.1)
  NZ_AFGF01000077 (original name was: NZ_AFGF01000077.1)
  NZ_AFGF01000076 (original name was: NZ_AFGF01000076.1)
  NZ_AFGF01000074 (original name was: NZ_AFGF01000074.1)
  NZ_AFGF01000073 (original name was: NZ_AFGF01000073.1)
  NZ_AFGF01000072 (original name was: NZ_AFGF01000072.1)
  NZ_AFGF01000071 (original name was: NZ_AFGF01000071.1)
  NZ_AFGF01000070 (original name was: NZ_AFGF01000070.1)
  NZ_AFGF01000069 (original name was: NZ_AFGF01000069.1)
  NZ_AFGF01000068 (original name was: NZ_AFGF01000068.1)
  NZ_AFGF01000066 (original name was: NZ_AFGF01000066.1)
  NZ_AFGF01000065 (original name was: NZ_AFGF01000065.1)
  NZ_AFGF01000063 (original name was: NZ_AFGF01000063.1)
  NZ_AFGF01000062 (original name was: NZ_AFGF01000062.1)
  NZ_AFGF01000061 (original name was: NZ_AFGF01000061.1)
  NZ_AFGF01000060 (original name was: NZ_AFGF01000060.1)
  NZ_AFGF01000057 (original name was: NZ_AFGF01000057.1)
  NZ_AFGF01000056 (original name was: NZ_AFGF01000056.1)
  NZ_AFGF01000055 (original name was: NZ_AFGF01000055.1)
  NZ_AFGF01000053 (original name was: NZ_AFGF01000053.1)
  NZ_AFGF01000052 (original name was: NZ_AFGF01000052.1)
  NZ_AFGF01000051 (original name was: NZ_AFGF01000051.1)
  NZ_AFGF01000049 (original name was: NZ_AFGF01000049.1)
  NZ_AFGF01000048 (original name was: NZ_AFGF01000048.1)
  NZ_AFGF01000047 (original name was: NZ_AFGF01000047.1)
  NZ_AFGF01000046 (original name was: NZ_AFGF01000046.1)
  NZ_AFGF01000043 (original name was: NZ_AFGF01000043.1)
  NZ_AFGF01000042 (original name was: NZ_AFGF01000042.1)
  NZ_AFGF01000041 (original name was: NZ_AFGF01000041.1)
  NZ_AFGF01000040 (original name was: NZ_AFGF01000040.1)
  NZ_AFGF01000039 (original name was: NZ_AFGF01000039.1)
  NZ_AFGF01000038 (original name was: NZ_AFGF01000038.1)
  NZ_AFGF01000037 (original name was: NZ_AFGF01000037.1)
  NZ_AFGF01000036 (original name was: NZ_AFGF01000036.1)
  NZ_AFGF01000035 (original name was: NZ_AFGF01000035.1)
  NZ_AFGF01000034 (original name was: NZ_AFGF01000034.1)
  NZ_AFGF01000033 (original name was: NZ_AFGF01000033.1)
  NZ_AFGF01000032 (original name was: NZ_AFGF01000032.1)
  NZ_AFGF01000030 (original name was: NZ_AFGF01000030.1)
  NZ_AFGF01000029 (original name was: NZ_AFGF01000029.1)
  NZ_AFGF01000028 (original name was: NZ_AFGF01000028.1)
  NZ_AFGF01000026 (original name was: NZ_AFGF01000026.1)
  NZ_AFGF01000025 (original name was: NZ_AFGF01000025.1)
  NZ_AFGF01000024 (original name was: NZ_AFGF01000024.1)
  NZ_AFGF01000023 (original name was: NZ_AFGF01000023.1)
  NZ_AFGF01000022 (original name was: NZ_AFGF01000022.1)
  NZ_AFGF01000021 (original name was: NZ_AFGF01000021.1)
  NZ_AFGF01000020 (original name was: NZ_AFGF01000020.1)
  NZ_AFGF01000019 (original name was: NZ_AFGF01000019.1)
  NZ_AFGF01000018 (original name was: NZ_AFGF01000018.1)
  NZ_AFGF01000017 (original name was: NZ_AFGF01000017.1)
  NZ_AFGF01000016 (original name was: NZ_AFGF01000016.1)
  NZ_AFGF01000015 (original name was: NZ_AFGF01000015.1)
  NZ_AFGF01000014 (original name was: NZ_AFGF01000014.1)
  NZ_AFGF01000013 (original name was: NZ_AFGF01000013.1)
  NZ_AFGF01000010 (original name was: NZ_AFGF01000010.1)
  NZ_AFGF01000008 (original name was: NZ_AFGF01000008.1)
  NZ_AFGF01000006 (original name was: NZ_AFGF01000006.1)
  NZ_AFGF01000005 (original name was: NZ_AFGF01000005.1)
  NZ_AFGF01000004 (original name was: NZ_AFGF01000004.1)
  NZ_AFGF01000001 (original name was: NZ_AFGF01000001.1)

Compact view
c00101_NZ_AFGF.. - Region 1 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 69,110 - 89,784 nt. (total: 20,675 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000622.1 |  | 0.13 | RiPP | megacin | Bacillus megaterium
BGC0000838.1 |  | 0.07 | Polyketide | flexirubin | Flavobacterium johnsoniae UW101
BGC0000195.1 |  | 0.06 | Polyketide | alnumycin A, alnumycin B, alnumycin C, alnumycin P, prealnumycin, thalnumycin A, thalnumycin B, K1115A, 1,6-dihydro-8-propylanthraquinone | Streptomyces sp. CM020
BGC0000200.1 |  | 0.05 | Polyketide, Saccharide | arixanthomycin A, arixanthomycin B, arixanthomycin C | uncultured bacterium
BGC0001740.1 |  | 0.04 | NRP, Polyketide | phthoxazolin | Streptomyces avermitilis
BGC0000379.1 |  | 0.04 | NRP | glycinocin A | Streptomyces viridochromogenes
BGC0000413.1 |  | 0.03 | NRP | pyoverdin | Pseudomonas protegens Pf-5

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000622.1 |  | 0.42 | RiPP | megacin | Bacillus megaterium
BGC0000838.1 |  | 0.27 | Polyketide | flexirubin | Flavobacterium johnsoniae UW101
BGC0000195.1 |  | 0.25 | Polyketide | alnumycin A, alnumycin B, alnumycin C, alnumycin P, prealnumycin, thalnumycin A, thalnumycin B, K1115A, 1,6-dihydro-8-propylanthraquinone | Streptomyces sp. CM020
BGC0000200.1 |  | 0.22 | Polyketide, Saccharide | arixanthomycin A, arixanthomycin B, arixanthomycin C | uncultured bacterium
BGC0001740.1 |  | 0.20 | NRP, Polyketide | phthoxazolin | Streptomyces avermitilis
BGC0000379.1 |  | 0.19 | NRP | glycinocin A | Streptomyces viridochromogenes
BGC0000413.1 |  | 0.17 | NRP | pyoverdin | Pseudomonas protegens Pf-5

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00134_NZ_AFGF.. - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 25,657 nt. (total: 25,657 nt) Show pHMM detection rules used
Region on contig edge.
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001615.1 |  | 0.32 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0001185.1 |  | 0.31 | NRP | bacillibactin | Bacillus velezensis FZB42
BGC0000401.1 |  | 0.26 | NRP | paenibactin | Paenibacillus elgii B69
BGC0001399.1 |  | 0.25 | NRP | fellutamide B | Aspergillus nidulans FGSC A4
BGC0001844.1 |  | 0.25 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0001149.1 |  | 0.25 | NRP, Saccharide | brabantamide A | Pseudomonas sp. SHC52
BGC0001825.1 |  | 0.25 | NRP | xenematide | Xenorhabdus nematophila AN6/1
BGC0001758.1 |  | 0.25 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001833.1 |  | 0.24 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001132.1 |  | 0.24 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001615.1 |  | 0.66 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0001185.1 |  | 0.64 | NRP | bacillibactin | Bacillus velezensis FZB42
BGC0000401.1 |  | 0.59 | NRP | paenibactin | Paenibacillus elgii B69
BGC0001399.1 |  | 0.58 | NRP | fellutamide B | Aspergillus nidulans FGSC A4
BGC0001844.1 |  | 0.58 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0001149.1 |  | 0.58 | NRP, Saccharide | brabantamide A | Pseudomonas sp. SHC52
BGC0001825.1 |  | 0.58 | NRP | xenematide | Xenorhabdus nematophila AN6/1
BGC0001758.1 |  | 0.58 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001833.1 |  | 0.58 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001132.1 |  | 0.58 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 0 - 25657:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (thr)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg134_3: thr
  Search NORINE for peptide: strict or relaxed
  AMP-binding (464..879): thr
  NRPSPredictor2: thr
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      thr
    Single AA prediction:
      thr
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DFWNIGMVHK
    Nearest Stachelhaus code:
      thr
    Stachelhaus code match:
      100% (strong)
ctg134_5: dhb
  Search NORINE for peptide: strict or relaxed
  AMP-binding (32..437): dhb
  NRPSPredictor2: dhb
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aromatic
    Large clusters prediction:
      dhb, sal
    Small clusters prediction:
      dhb, sal
    Single AA prediction:
      dhb
  Stachelhaus prediction details:
    Stachelhaus sequence:
      PLPsQGsVNK
    Nearest Stachelhaus code:
      dhb
    Stachelhaus code match:
      80% (moderate)

c00155_NZ_AFGF.. - Region 1 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 40,141 - 59,655 nt. (total: 19,515 nt) Show pHMM detection rules used
Region on contig edge.
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000858.1 |  | 0.23 | Other | ectoine | Methylobacter marinus
BGC0000852.1 |  | 0.23 | Other | ectoine | Sporosarcina pasteurii
BGC0000856.1 |  | 0.22 | Other | ectoine | Methylophaga thalassica
BGC0000855.1 |  | 0.22 | Other | ectoine | Methylomicrobium kenyense
BGC0000857.1 |  | 0.18 | Other | ectoine | Methylophaga alcalica
BGC0000854.1 |  | 0.17 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000938.1 |  | 0.16 | Other (Aminocoumarin) | fosfomycin | Streptomyces fradiae
BGC0000501.1 |  | 0.16 | RiPP | catenulipeptin | Catenulispora acidiphila DSM 44928
BGC0000563.1 |  | 0.16 | RiPP | venezuelin | Streptomyces venezuelae ATCC 10712
BGC0000551.1 |  | 0.16 | RiPP | SapB | Streptomyces coelicolor A3(2)

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000858.1 |  | 0.56 | Other | ectoine | Methylobacter marinus
BGC0000852.1 |  | 0.56 | Other | ectoine | Sporosarcina pasteurii
BGC0000856.1 |  | 0.55 | Other | ectoine | Methylophaga thalassica
BGC0000855.1 |  | 0.55 | Other | ectoine | Methylomicrobium kenyense
BGC0000857.1 |  | 0.49 | Other | ectoine | Methylophaga alcalica
BGC0000854.1 |  | 0.49 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000938.1 |  | 0.47 | Other (Aminocoumarin) | fosfomycin | Streptomyces fradiae
BGC0000501.1 |  | 0.47 | RiPP | catenulipeptin | Catenulispora acidiphila DSM 44928
BGC0000563.1 |  | 0.47 | RiPP | venezuelin | Streptomyces venezuelae ATCC 10712
BGC0000551.1 |  | 0.47 | RiPP | SapB | Streptomyces coelicolor A3(2)

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00159_NZ_AFGF.. - Region 1 - hserlactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 36,677 - 57,423 nt. (total: 20,747 nt) Show pHMM detection rules used
hserlactone: Autoind_synth

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | hserlactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000903.1 |  | 0.14 | Other | fluorometabolite | Streptomyces cattleya
BGC0001783.1 |  | 0.14 | Other | streptonigrin | Streptomyces flocculus
BGC0000678.1 |  | 0.09 | Terpene | pentalenolactone | Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0001538.1 |  | 0.09 | NRP, Polyketide | caboxamycin | Streptomyces sp. NTK 937
BGC0001366.1 |  | 0.08 | Polyketide | BE-24566B, zunyimycin A | Streptomyces sp. FJS31-2
BGC0001298.1 |  | 0.08 | Polyketide | 4-Z-annimycin | Streptomyces calvus
BGC0000847.1 |  | 0.07 | Other (Non-NRP beta-lactam) | thienamycin | Streptomyces cattleya
BGC0001302.1 |  | 0.06 | Other | lomofungin | Streptomyces lomondensis
BGC0001536.1 |  | 0.06 | NRP | brevicidine | Brevibacillus laterosporus
BGC0000723.1 |  | 0.06 | Saccharide | β-D-galactosylvalidoxylamine-A | Streptomyces hygroscopicus subsp. limoneus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000903.1 |  | 0.44 | Other | fluorometabolite | Streptomyces cattleya
BGC0001783.1 |  | 0.43 | Other | streptonigrin | Streptomyces flocculus
BGC0000678.1 |  | 0.34 | Terpene | pentalenolactone | Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0001538.1 |  | 0.32 | NRP, Polyketide | caboxamycin | Streptomyces sp. NTK 937
BGC0001366.1 |  | 0.31 | Polyketide | BE-24566B, zunyimycin A | Streptomyces sp. FJS31-2
BGC0001298.1 |  | 0.30 | Polyketide | 4-Z-annimycin | Streptomyces calvus
BGC0000847.1 |  | 0.28 | Other (Non-NRP beta-lactam) | thienamycin | Streptomyces cattleya
BGC0001302.1 |  | 0.27 | Other | lomofungin | Streptomyces lomondensis
BGC0001536.1 |  | 0.27 | NRP | brevicidine | Brevibacillus laterosporus
BGC0000723.1 |  | 0.26 | Saccharide | β-D-galactosylvalidoxylamine-A | Streptomyces hygroscopicus subsp. limoneus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00193_NZ_AFGF.. - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 61,407 nt. (total: 61,407 nt) Show pHMM detection rules used
Region on contig edge.
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000426.1 |  | 0.39 | NRP | sevadicin | Paenibacillus larvae
BGC0001844.1 |  | 0.35 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0001131.1 |  | 0.34 | NRP | ambactin | Xenorhabdus miraniensis
BGC0000389.1 |  | 0.34 | NRP | massetolide A | Pseudomonas fluorescens SS101
BGC0001833.1 |  | 0.34 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001615.1 |  | 0.34 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0001796.1 |  | 0.34 | NRP | tauramamide | Brevibacillus laterosporus DSM 25
BGC0001161.1 |  | 0.33 | Polyketide | 1-heptadecene | Moorea bouillonii PNG
BGC0000301.1 |  | 0.33 | NRP | anabaenopeptin 908, anabaenopeptin 915 | Planktothrix agardhii NIVA-CYA 126/8
BGC0001162.1 |  | 0.33 | Polyketide | 1-heptadecene | Moorea producens JHB

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000426.1 |  | 0.71 | NRP | sevadicin | Paenibacillus larvae
BGC0001844.1 |  | 0.68 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0001131.1 |  | 0.67 | NRP | ambactin | Xenorhabdus miraniensis
BGC0000389.1 |  | 0.67 | NRP | massetolide A | Pseudomonas fluorescens SS101
BGC0001833.1 |  | 0.67 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001615.1 |  | 0.67 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0001796.1 |  | 0.67 | NRP | tauramamide | Brevibacillus laterosporus DSM 25
BGC0001161.1 |  | 0.67 | Polyketide | 1-heptadecene | Moorea bouillonii PNG
BGC0000301.1 |  | 0.67 | NRP | anabaenopeptin 908, anabaenopeptin 915 | Planktothrix agardhii NIVA-CYA 126/8
BGC0001162.1 |  | 0.67 | Polyketide | 1-heptadecene | Moorea producens JHB

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 0 - 61407:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (ohmal - ile - D-leu) + (leu) + (D-glu) + (X - leu - glu - ile) + (D-X - leu)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg193_5: pk
  CAL_domain (45..490): pk
  minowa: NH2
  Prediction, score:
    NH2: 190.3
    fatty_acid: 18.9
    AHBA: 14.5
    shikimic_acid: 0.0
    Acetyl-CoA: -3.2
ctg193_7: mal - ile - leu
  Search NORINE for peptide: strict or relaxed
  PKS_AT (0..286): mal
  ATSignature: Malonyl-CoA
  Top 3 matches:
    Malonyl-CoA: 75.0%
    Methylmalonyl-CoA: 62.5%
    Propionyl-CoA: 58.3%
  minowa: Malonyl-CoA
  Prediction, score:
    Malonyl-CoA: 137.3
    Methylmalonyl-CoA: 137.2
    Methoxymalonyl-CoA: 102.6
    Ethylmalonyl-CoA: 102.3
    Isobutyryl-CoA: 94.1
    inactive: 73.1
    Benzoyl-CoA: 68.8
    Acetyl-CoA: 63.5
    Propionyl-CoA: 61.2
    fatty_acid: 52.8
    trans-1,2-CPDA: 45.9
    CHC-CoA: 36.6
    2-Methylbutyryl-CoA: 33.8
    3-Methylbutyryl-CoA: 30.7
  AMP-binding (1441..1836): ile
  NRPSPredictor2: ile
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      val, leu, ile, abu, iva
    Single AA prediction:
      ile
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DGFFLGVVFK
    Nearest Stachelhaus code:
      ile
    Stachelhaus code match:
      100% (strong)
  AMP-binding (2477..2868): leu
  NRPSPredictor2: leu
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      val, leu, ile, abu, iva
    Single AA prediction:
      leu
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAWFLGhVVK
    Nearest Stachelhaus code:
      leu
    Stachelhaus code match:
      90% (moderate)
ctg193_8: leu
  Search NORINE for peptide: strict or relaxed
  AMP-binding (481..872): leu
  NRPSPredictor2: leu
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      val, leu, ile, abu, iva
    Single AA prediction:
      leu
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAWFLGhVVK
    Nearest Stachelhaus code:
      leu
    Stachelhaus code match:
      90% (moderate)
ctg193_9: glu
  Search NORINE for peptide: strict or relaxed
  AMP-binding (278..680): glu
  NRPSPredictor2: glu
  SVM prediction details:
    NOTE: outside applicability domain
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAKDLGVdvK
    Nearest Stachelhaus code:
      glu
    Stachelhaus code match:
      80% (moderate)
ctg193_10: X - leu - glu - ile
  Search NORINE for peptide: strict or relaxed
  AMP-binding (478..881): X
  NRPSPredictor2: gly, ala
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      N/A
    Small clusters prediction:
      gly, ala
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWdFaLVyK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      70% (weak)
  AMP-binding (1523..1914): leu
  NRPSPredictor2: leu
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      val, leu, ile, abu, iva
    Single AA prediction:
      leu
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAWFLGhVVK
    Nearest Stachelhaus code:
      leu
    Stachelhaus code match:
      90% (moderate)
  AMP-binding (2555..2956): glu
  NRPSPredictor2: glu
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      glu, gln
    Single AA prediction:
      glu
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAWQFGqvDK
    Nearest Stachelhaus code:
      gln
    Stachelhaus code match:
      80% (moderate)
  AMP-binding (3598..3993): ile
  NRPSPredictor2: ile
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      val, leu, ile, abu, iva
    Single AA prediction:
      ile
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DGFFLGVVFK
    Nearest Stachelhaus code:
      ile
    Stachelhaus code match:
      100% (strong)
ctg193_18: X - leu
  Search NORINE for peptide: strict or relaxed
  AMP-binding (472..862): X
  NRPSPredictor2: (unknown)
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      N/A
    Small clusters prediction:
      phe, trp
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAwLIGAViK
    Nearest Stachelhaus code:
      val
    Stachelhaus code match:
      80% (moderate)
  AMP-binding (1969..2360): leu
  NRPSPredictor2: leu
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      val, leu, ile, abu, iva
    Single AA prediction:
      leu
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAWFLGhVVK
    Nearest Stachelhaus code:
      leu
    Stachelhaus code match:
      90% (moderate)

c00196_NZ_AFGF.. - Region 1 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 7,828 - 48,871 nt. (total: 41,044 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T3PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000282.1 |  | 0.36 | Polyketide | alkylresorcinol | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001962.1 |  | 0.32 | Polyketide | hierridin B, hierridin C | Cyanobium sp. LEGE 06113
BGC0001938.1 |  | 0.32 | Polyketide | entotheonella | Candidatus Entotheonella serta
BGC0001831.1 |  | 0.22 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0000880.1 |  | 0.21 | Other (Nucleoside) | tunicamycin B1 | Streptomyces chartreusis NRRL 3882
BGC0001861.1 |  | 0.21 | RiPP | bacillicin BAG2O | Bacillus cereus BAG2O-1
BGC0001862.1 |  | 0.20 | RiPP | geocillicin | Aeribacillus pallidus
BGC0001930.1 |  | 0.20 | RiPP | pallidocin | Aeribacillus pallidus
BGC0000484.1 |  | 0.20 | RiPP | glycocin F | Lactobacillus plantarum
BGC0000722.1 |  | 0.20 | Other (Cyclitol), Polyketide | validamycin A | Streptomyces hygroscopicus subsp. jinggangensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000282.1 |  | 0.69 | Polyketide | alkylresorcinol | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001962.1 |  | 0.66 | Polyketide | hierridin B, hierridin C | Cyanobium sp. LEGE 06113
BGC0001938.1 |  | 0.65 | Polyketide | entotheonella | Candidatus Entotheonella serta
BGC0001831.1 |  | 0.55 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0000880.1 |  | 0.54 | Other (Nucleoside) | tunicamycin B1 | Streptomyces chartreusis NRRL 3882
BGC0001861.1 |  | 0.53 | RiPP | bacillicin BAG2O | Bacillus cereus BAG2O-1
BGC0001862.1 |  | 0.53 | RiPP | geocillicin | Aeribacillus pallidus
BGC0001930.1 |  | 0.53 | RiPP | pallidocin | Aeribacillus pallidus
BGC0000484.1 |  | 0.53 | RiPP | glycocin F | Lactobacillus plantarum
BGC0000722.1 |  | 0.52 | Other (Cyclitol), Polyketide | validamycin A | Streptomyces hygroscopicus subsp. jinggangensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

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Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
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Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
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