LOCUS       NZ_CP033238.1          11041 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP033238.1 Saccharolobus solfataricus strain SULM chromosome,
            complete genome.
ACCESSION   NZ_CP033238
VERSION     NZ_CP033238.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:21:32
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 502809
            Orig. end    :: 513850
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11041
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[507809:508850](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..6041)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..11041
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11041
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             603..1379
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_565"
                     /sec_met_domain="PF04055 (E-value: 9.1e-13, bitscore: 46.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVKSIRVKSALSKSGLKELNYSLNPYLGCVFSCPYCYAPNFTPD
                     REASENWGKVVAVKENLLEVLEREVKIYKRGVVGISTITDAYQPIEALRKLTRESLKIL
                     LKNGFRVSIQTKSPLVLRDIDVLLEYKDRVDVGFTVTSLNNKLEPNAPPAKGRLRALEE
                     LSNEGLETWIFLGPIIQGVNDTEVENIIREISNIKARVIFDSFHYYRGLKFKEGSIHWW
                     VNLKNKILENCKRYSIECHEQSEDWIYEKKRYYKTF"
     PFAM_domain     675..1184
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_565_0026"
                     /evalue="4.60E-12"
                     /label="ctg1_565"
                     /locus_tag="ctg1_565"
                     /protein_end="194"
                     /protein_start="24"
                     /score="46.7"
                     /tool="antismash"
                     /translation="NPYLGCVFSCPYCYAPNFTPDREASENWGKVVAVKENLLEVLERE
                     VKIYKRGVVGISTITDAYQPIEALRKLTRESLKILLKNGFRVSIQTKSPLVLRDIDVLL
                     EYKDRVDVGFTVTSLNNKLEPNAPPAKGRLRALEELSNEGLETWIFLGPIIQGVNDTEV
                     ENIIREI"
     CDS             complement(1382..1720)
                     /locus_tag="ctg1_566"
                     /transl_table=11
                     /translation="MSEKLDKLMQLKGAIAAGQYTPDGKLVEYKGPMSKEIAEMVAKMV
                     AANTLMGTVEAESFTKISGMRWTPFLGWAVAAGEYAVCVMGNYGVFVKLAEADFNQIFK
                     TLREVAGI"
     PFAM_domain     complement(1397..1711)
                     /aSDomain="DUF2173"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09941.11"
                     /description="Uncharacterized conserved protein (DUF2173)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_566_0027"
                     /evalue="2.20E-39"
                     /label="ctg1_566"
                     /locus_tag="ctg1_566"
                     /protein_end="108"
                     /protein_start="3"
                     /score="134.1"
                     /tool="antismash"
                     /translation="KLDKLMQLKGAIAAGQYTPDGKLVEYKGPMSKEIAEMVAKMVAAN
                     TLMGTVEAESFTKISGMRWTPFLGWAVAAGEYAVCVMGNYGVFVKLAEADFNQIFKTLR
                     E"
     CDS             complement(1928..3181)
                     /locus_tag="ctg1_567"
                     /transl_table=11
                     /translation="MIKYKDTRWMYLIIPYNASTGPLSTLVTLQILSLGGNAINVAYAI
                     SLSNAVLIPASILWGFMADRMDRKKQILLSLAGVSIPLVFMPFMNSISLVTLNYALITF
                     MSTASATPFNLLIMESVEKKHWGSLFSRFSLFSSIGVLLGLVISTFLVILLRIDQIEEI
                     LGFSVLATLIASIKILPKPIITFERTAIIHHKESFLTRMRHLPMMFLHLPNIHHFKMFS
                     MTRLFRKPINYVPLLYLGIVLFYISSGIFNTVYPAGLYVKGLNKSEVLAVISVGMVFQI
                     LGFRISSMLLESKDEKGLAHISLILRGVSYVVLGIFAQLFLGIPIFISGLIFYPLAAGI
                     AYAIFYSSSTTLIFKIVGERRQGTGLGVYSTVVGISLFLGSLLSGYITHYISYGIDFIT
                     AGIILLFASWIFRYLEEG"
     PFAM_domain     complement(2015..3085)
                     /aSDomain="MFS_1_like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12832.9"
                     /description="MFS_1 like family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_567_0028"
                     /evalue="1.40E-07"
                     /label="ctg1_567"
                     /locus_tag="ctg1_567"
                     /protein_end="389"
                     /protein_start="32"
                     /score="30.8"
                     /tool="antismash"
                     /translation="SLGGNAINVAYAISLSNAVLIPASILWGFMADRMDRKKQILLSLA
                     GVSIPLVFMPFMNSISLVTLNYALITFMSTASATPFNLLIMESVEKKHWGSLFSRFSLF
                     SSIGVLLGLVISTFLVILLRIDQIEEILGFSVLATLIASIKILPKPIITFERTAIIHHK
                     ESFLTRMRHLPMMFLHLPNIHHFKMFSMTRLFRKPINYVPLLYLGIVLFYISSGIFNTV
                     YPAGLYVKGLNKSEVLAVISVGMVFQILGFRISSMLLESKDEKGLAHISLILRGVSYVV
                     LGIFAQLFLGIPIFISGLIFYPLAAGIAYAIFYSSSTTLIFKIVGERRQGTGLGVYSTV
                     VGISLFLGSLLSGYITH"
     CDS             3337..4125
                     /locus_tag="ctg1_568"
                     /transl_table=11
                     /translation="MKIKKGDTEAEILTKGAYLYSFKIGNRDMILRGDLERPTRGGMAI
                     LIPFANRVKNAEYVFEGVKYTLPQNREGNAIHGLVMDKEFNVIGKSEDSISLQYILEHE
                     GYPSKLDCVITYKVFKYGLRIKIVVRNVGNKRAPLTVGAHPYFITADDWRIVVEKEESI
                     KKCISFNKIPTGELVKTKLEHTDYDDCFLISGGIQLHSSYSKVRITRRNMPFVQIYTGV
                     RGSIAIEPMSGAPDAYHNGLGLKILEPNESSYFAFAFRFH"
     PFAM_domain     3343..4101
                     /aSDomain="Aldose_epim"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01263.22"
                     /description="Aldose 1-epimerase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_568_0029"
                     /evalue="8.50E-36"
                     /label="ctg1_568"
                     /locus_tag="ctg1_568"
                     /protein_end="255"
                     /protein_start="2"
                     /score="123.9"
                     /tool="antismash"
                     /translation="IKKGDTEAEILTKGAYLYSFKIGNRDMILRGDLERPTRGGMAILI
                     PFANRVKNAEYVFEGVKYTLPQNREGNAIHGLVMDKEFNVIGKSEDSISLQYILEHEGY
                     PSKLDCVITYKVFKYGLRIKIVVRNVGNKRAPLTVGAHPYFITADDWRIVVEKEESIKK
                     CISFNKIPTGELVKTKLEHTDYDDCFLISGGIQLHSSYSKVRITRRNMPFVQIYTGVRG
                     SIAIEPMSGAPDAYHNGLGLKILEPNESSYF"
     CDS             4197..5006
                     /locus_tag="ctg1_569"
                     /transl_table=11
                     /translation="MPYAEEMEVKASRSQLLSFFIDPVRFAGILGHLMIVNIFDKAESK
                     FVTMGSLKKPENKFKVLYLIGDPESRLITFSGIMEGPTLTFNTITYKGEGDNGKLTWRI
                     DLILTELGKLTRMKVAADVKQSYGFLDRVRIGDFDFATHLVKEHVIPFVKFYFKPSILE
                     ETPVLNEVFRFRGSVEEVILKLREVIVNIKQGGIIILGDDYNIITSIVNGEVSHAQINN
                     MDVPGSEVFAYLLKASGNVELIAYDISLDDLIFKNLKRRLEEVKAKS"
     CDS             complement(5001..6041)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Linocin_M18"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_570"
                     /sec_met_domain="Linocin_M18 (E-value: 4e-49, bitscore:
                     164.5, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LFSNDPSTLTRKEKFDKEESVRAIRNAIAAEIDAINFYLQQNKYI
                     DDEKLRKVHEDITKEEMTHFGEFLRLLYQVSPEDFSYFKKGWEEASKLIGETKDFPLIP
                     TSSKEISKDHIVSWITEGIVSSRIMRNIGNTIKYEFTTIPLSEIKEDSGDIIQSKSASL
                     YEVPLINSQVKFYLGQKSDSRRTAVLAGKSFAKMENYLLLKNHPLSPLKIGLKITGSDW
                     NVAGNILLDVLRAYENLTREGFGKDVYILMSSLNYSKTFRVVDRSGTYEIEMIKEIGNV
                     VPTDIVSNDEIYVISKQGFDILVFSDLNVEYLSKEKDYEVYLITEQIAPRLISSAASCV
                     ITQKTS"
     PFAM_domain     complement(5055..5750)
                     /aSDomain="Linocin_M18"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04454.14"
                     /description="Encapsulating protein for peroxidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_570_0030"
                     /evalue="2.30E-47"
                     /label="ctg1_570"
                     /locus_tag="ctg1_570"
                     /protein_end="329"
                     /protein_start="97"
                     /score="161.5"
                     /tool="antismash"
                     /translation="KDFPLIPTSSKEISKDHIVSWITEGIVSSRIMRNIGNTIKYEFTT
                     IPLSEIKEDSGDIIQSKSASLYEVPLINSQVKFYLGQKSDSRRTAVLAGKSFAKMENYL
                     LLKNHPLSPLKIGLKITGSDWNVAGNILLDVLRAYENLTREGFGKDVYILMSSLNYSKT
                     FRVVDRSGTYEIEMIKEIGNVVPTDIVSNDEIYVISKQGFDILVFSDLNVEYLSKEKDY
                     EVYLITEQIA"
     CDS             complement(6276..7625)
                     /locus_tag="ctg1_571"
                     /transl_table=11
                     /translation="MVCEIPRVTVTTWSSRSIILVGPTYRKYLEKTLEIVRNNEVASVV
                     GQPGMGKTTLLKKIEEITKTDNLSIYLDLANKQSIDEEFWTKTTQFELREKALLELQKI
                     KGKLGYSFWKRLMGVKFEDWLLKICNKYNNPFLRVYCLSYERNFDGMINALRDMKNLSK
                     LVLLIDEIRDYHLSLIHRLINAGLDIPIIMAMPTEVYSKVSDLAIRRRIEESRIPLDDA
                     LTSEDIKEIVEAYCKDLTEDILPIIITLWNSKEITNVSSILQFIRNEMDKVEKVCEKNN
                     IDCIRSELRKYTSLRNPEVDAKEFEKKVRELLSNISKEFGISYVHPRGKRIEVDGKSIV
                     VGLFFIVDDQVYLGDVVFSNDGSLYNYEELKLLSKIEEVEHDKKVYKVRGRFVITNTAT
                     NINNIYTLNIPTLEVVKILNGDVFLLEERLKILFDQYQTPTRNETENLAL"
     CDS             complement(7628..8128)
                     /locus_tag="ctg1_572"
                     /transl_table=11
                     /translation="MIGKDDVFALILSEYKDSQKPVSLSKIKRKFKDRNLIHVLEELEK
                     EGKIRRVENGSKITFEPLDSINIEDELKILRDEIHKMLDLLQKFVESKSFSSKDFDEAY
                     DRIRDSLGYAPLERIRIELGLSKEEFYSKFRKYVEENYDLIAGGDEGFTRRGVTYGIVK
                     RRR"
     CDS             complement(8366..9532)
                     /locus_tag="ctg1_573"
                     /transl_table=11
                     /translation="MIRPIILPPKSPFSDIKGGVGTPYVIYDSKRDKHWFLFTGWSDLK
                     GLKREGFVAPIDRSLNVDFSGIKKILPSDFPMQVDYSNNGIRGFYNEARDEFYITSTHG
                     NDVYFFAFDQEWKLKGYKLLIKDLKKDSGFPIRPTGAYRNMHDAFAVAPNADSSGVKLY
                     MVRSVDDLEKVRVEDLGDIGAWARSNDVLDFTLIPRFQIFIEMNTVSKWMLQSFIGPNL
                     DELYVTEDVNKVSFLQGSLMPLLGLDDSFVQVGHPHYTTEPDGKPKLFFVSFRDTYTTR
                     IDTGKEGYTHEIWVEYVDTFIFDPRSYGELRGKFKGRESKWYYVPNANRLIVSVNGEAE
                     LQLKADINDEVSDSVVLKRGINIIDKPTTWIRLSSSTEIGATIKALVY"
     CDS             complement(9589..10131)
                     /locus_tag="ctg1_574"
                     /transl_table=11
                     /translation="MNRLQQLLKEALDEIEIYGSWVSLYYILKLLAESNVEKLCKEQEV
                     AYHMTVDSLTLFTIYKYGGGIDKTRLFVLSFLLYDYLSRYYNIQNPIFSIKWNKRYFVY
                     SPRIDSRLHTLSKKSLILKKERLYYLNQLGRSEAESINIREKDNAKVDSIVTNLKSLKK
                     VKDIRIFVRRHLLGNDK"
ORIGIN
        1 tccaggatat taagtattgg tggaattgga aaggaaagaa aattagtacc tactagatgg
       61 agtataacag cagtggataa ggctatttcc gatactctaa ttgagaatat aaagaattat
      121 gacacgatag acaaggttga agtttatttc agaaaatata ataagaatct tttcatcgca
      181 attcttcttc ctagagattg gagctttgaa tggggagaag cctggtatcc tggaagtacc
      241 tggaataagt ttggcaacta tgttgatata gaagtggata acgaaaggta tcatggtaga
      301 tctgattatc cagaaatagg cggttgttat tatgcttcta gattaggtgt gacggaattc
      361 ttggcaagca gaaagagaca agccactgca atattatgga gggagatata tgaaggattt
      421 aacttgccag taggtgtttg gtttgttagg gaaaacgtta aggaaatgtt taaaggtaag
      481 ccagtagtat ttgacgacat aagtactgcc ttaaatttcg ttaaaagatt attaagatct
      541 gatttaaagc agtggttaag taagtcatta ctctccttta ataccattga taagtggtta
      601 aaatgattgt aaagtccatt agggtgaaat ctgctttaag taaatctgga ttgaaagagt
      661 taaactatag tctaaatcct tatttaggtt gtgtattttc ttgcccctat tgttatgccc
      721 ccaatttcac tccagatagg gaggcttcag aaaattgggg gaaagttgta gccgttaagg
      781 agaacttgct tgaggtttta gagagagaag tgaaaatcta taagagggga gtagttggga
      841 tatctacaat aactgatgct tatcaaccga tagaggcttt aagaaagctt actagggaaa
      901 gcctaaagat attattaaag aatggtttca gagtttcaat tcagactaag tcacccttag
      961 ttttaaggga tattgacgta ctcttagaat acaaggatag agttgatgtt ggatttacag
     1021 ttactagttt aaataataag ttagaaccta acgcacctcc agctaaaggt agattaagag
     1081 ccttagagga actcagtaat gaagggctgg aaacttggat tttcctagga cctattattc
     1141 aaggtgtaaa tgatactgag gtagagaata taattcgtga aatttcaaat atcaaagcaa
     1201 gggtaatttt cgatagtttt cattactata gggggttaaa atttaaggag ggttctatac
     1261 attggtgggt taatttgaag aataaaatat tagagaattg taagaggtac agtatagagt
     1321 gccatgaaca aagtgaggac tggatttatg aaaaaaagag atattataaa accttttagc
     1381 cttatattcc ggctacttct cttaatgttt tgaatatttg attgaaatct gcctcagcaa
     1441 gtttaacaaa cactccataa tttcccatta cgcatactgc atactctcct gcagctacag
     1501 cccaccctaa aaacggagtc catctcattc cagaaatttt cgtgaaagac tctgcttcca
     1561 cagttcccat taaagtgtta gctgccacca tctttgctac catctcagca atctctttag
     1621 acatcggtcc cttatactct acaagtttcc catccggtgt atattgtcca gctgctattg
     1681 ctccttttaa ttgcattagt ttatcgagct tttcactcat tttttatacc tctactaaat
     1741 attagataaa tcattttaat aaattttatg attaaacatt ataaaaaatc ataatatatc
     1801 aagttttatc ttatttattt tctctagggt ttaactaaat agcatatgaa gtcgtcctaa
     1861 aagtcacatc gataaaatat cataaagttt aaatattagt ttatttttac taaaaattaa
     1921 gataaaatca tccttcctct agatatctaa atatccacga agcaaataag agtattatcc
     1981 ccgctgttat aaaatctata ccgtagctga tatagtgcgt gatataacct gacaaaagcg
     2041 atcctagaaa taacgatatc cctactacag tactgtaaac tccgagccca gttccttgtc
     2101 tcctctcccc aacaattttg aatattaagg tagtagatga ggagtagaaa attgcatagg
     2161 caattccagc tgccaacgga taaaatatta acccagatat aaatattggt atacctaaaa
     2221 ataattgagc aaatatacca agtacaacat aagatactcc tcttaggata agtgaaatgt
     2281 gtgctaatcc tttttcatct ttactttcaa gtagcattga ggatattcta aatcctaaaa
     2341 tttgaaatac cataccgacg cttattacag ccaacacctc agatttattt aaccctttca
     2401 cgtacaagcc agctggataa actgtattga atattccact acttatgtaa aataacacta
     2461 ttcctagata cagtaaagga acgtaattaa tgggtttcct aaataatcta gtcatggaga
     2521 acattttgaa gtgatgaata ttaggtaaat gaaggaacat cattggcaag tgtctcattc
     2581 tagttaaaaa tgactcttta tggtgtatga tagcagtcct ttcaaaagta attataggtt
     2641 taggtagtat ctttatgctt gctattaacg tagctaatac tgaaaatccc aatatttcct
     2701 ctatttggtc aattcttaag agaattacca gaaaagtcga aataactaat cccagcaaga
     2761 cacctatgga ggagaataag gagaaccttg agaaaagaga accccagtgt tttttctcaa
     2821 cggactccat tattaataaa ttgaacggtg tagctgacgc agtactcata aatgtgatta
     2881 aagcgtagtt taaggtgact agtgagatac tgttcatgaa tggcataaag acaagtggga
     2941 ttgaaacccc agctaggctt aacaatattt gtttctttct atccatcctg tcagccataa
     3001 atccccataa tattgaagct ggaattagaa cagcgttact tagggatatg gcgtatgcta
     3061 cgttaatcgc atttcctcca agcgagagaa tctgtaacgt tactaatgtt gacaatggtc
     3121 ccgttgaagc gttatagggt attattagat acatccatct ggtatcctta tacttaatca
     3181 ttacttgttt tagccacaat gtaatgttta aaaattttat tgtaaagttt aacgagcaat
     3241 atatccttgg ttaagtttaa attttttaaa tataggaaac aagagaatgc tcagagacag
     3301 aaaataaatt taatcccagt ccgaatgtga aagtgtatga aaataaaaaa gggagatact
     3361 gaagctgaaa ttttaacaaa aggtgcctat ctttattcgt ttaaaattgg aaatagggac
     3421 atgatattaa gaggagattt ggagagacct acaaggggtg gtatggcaat cctaatacca
     3481 tttgcaaata gagtgaaaaa tgccgaatat gtatttgaag gagtaaaata cactttacct
     3541 caaaatagag agggaaacgc aatacatgga ttagtcatgg acaaggagtt caacgttata
     3601 ggaaaaagtg aggatagtat cagcttgcaa tatattctag aacatgaagg atatccttcc
     3661 aagctcgatt gtgttataac ctacaaggtt ttcaaatacg gacttaggat aaagatagtt
     3721 gtaagaaacg taggaaataa aagagcacca ttaacggttg gtgcacatcc atactttatt
     3781 acggcagatg attggagaat agtagtggaa aaggaggaaa gtataaagaa gtgcataagt
     3841 ttcaataaaa ttcctactgg ggaattggta aagactaaac ttgaacacac tgattacgat
     3901 gactgtttct tgataagtgg aggtattcag ctacattcat cctattcaaa agtgagaatt
     3961 acaagaagaa acatgccatt tgtacaaata tatactggcg taagaggctc aattgcgata
     4021 gaacccatga gcggtgcccc agatgcatat cataatggtt taggacttaa aatattagaa
     4081 ccaaatgaga gctcatattt tgcgtttgcg tttcgtttcc attgaatata tttatacatc
     4141 ggtaatcttc tatataaatc aataaggttt atattttaaa attatatagt agatttatgc
     4201 cctatgcaga agaaatggaa gtgaaagcta gtagatctca attactgtca ttctttatag
     4261 acccagtgag atttgctgga atattaggtc acctgatgat tgtgaatata tttgataagg
     4321 ccgaaagtaa attcgtaaca atgggtagtc taaaaaagcc tgaaaataag ttcaaagttc
     4381 tttatttaat cggagatcca gaatcacgat taataacgtt ttcaggtata atggagggac
     4441 ctacacttac gtttaatacc attacatata agggagaagg agataatggg aaattaacgt
     4501 ggaggataga tcttatctta acagaattag gtaaactaac aagaatgaaa gttgctgcag
     4561 atgttaagca aagctatggt tttctagata gagtcagaat aggagatttt gattttgcaa
     4621 cgcatttagt aaaagagcat gtaataccat ttgttaaatt ttattttaag ccctctatct
     4681 tggaagaaac tccagtcctc aatgaggtat ttagatttag agggagtgtt gaagaggtta
     4741 tattgaaatt aagagaggtt atagtaaata ttaaacaagg aggtataatt attcttggag
     4801 atgattataa tataataaca tccatagtca atggagaagt ctctcatgct cagataaata
     4861 atatggatgt acctggaagt gaggtttttg catatctact taaggcgagc ggaaatgtag
     4921 aattaatagc ctatgatatt tccttagatg acttgatatt taagaactta aaaagaagat
     4981 tggaggaagt gaaagctaaa tcatgatgtt ttttgcgtaa ttacgcaaga agcagcgcta
     5041 ctaattaatc taggtgcaat ttgctcagtg atcaaatata cctcatagtc cttttctttg
     5101 gacaagtact cgacgttaag gtcagagaac actaatatgt caaatccctg cttactgatg
     5161 acgtaaattt catcattact aactatgtcc gtaggtacta cattccctat ttcctttatc
     5221 atttcaattt cgtaggtgcc acttctatca accaccctga aggttttaga gtagtttaag
     5281 ctagacatta gtatgtaaac gtctttaccg aatccttctc gagttaaatt ttcatacgct
     5341 cttagaacat cgagtagtat atttccagcg acattccagt cagaacctgt aattttcaag
     5401 ccgattttta gaggagataa cggatgattt tttaataata aataattctc catcttagca
     5461 aaagattttc cagctaatac ggctgttctt ctcgaatcgc tcttctgacc caaataaaat
     5521 tttacttgag aattaattaa cggaacttca tagagtgatg cacttttgct ttgaattata
     5581 tctccggaat cctcttttat ttctgataaa ggtatggtgg taaactcata ttttattgta
     5641 tttcctatat tcctcattat tctactcgac acaattccct cagttatcca gctcactata
     5701 tggtctttgg aaatctcctt actactagtt ggaattaaag gaaaatcctt ggtttcacca
     5761 atcagttttg aagcttcttc ccatcccttt ttaaaataac tgaaatcctc tggagaaact
     5821 tgatatagta gtcttaggaa ttctccaaaa tgagtcattt cctctttagt tatgtcttca
     5881 tgtacttttc ttaatttctc gtcatcaata tatttatttt gttgtagata aaaatttata
     5941 gcatctattt ctgcagctat tgcatttctt atagctctga ctgattcctc tttatcaaat
     6001 ttttcttttc tagttaaagt tgagggatca ttagagaaca aaacttagca cccattactc
     6061 tataagcgtt tacgtataaa agttataaag tctctttggc tttatctaca attgcactca
     6121 ttagctagtt tgtagatttt tatcagatat ttaagaatca ttactaactt aaattgtaca
     6181 ctttaacatt gaccgaaatg gagataatat agtgatctag tgtaaaaata ttcaataggt
     6241 aaatcaagca aatactcact ctcttttccc ttatattaaa gggcgaggtt ttctgtctca
     6301 ttccttgtag gtgtttgata ttgatcgaaa aggatcttta atctctcttc taataggaag
     6361 acgtcaccat tcaatatttt cacaacttct agcgtaggga tatttagtgt gtaaatgtta
     6421 ttaatattag tagcggtgtt tgttattacg aatcttcccc taaccttata tactttctta
     6481 tcatgttcca cttcctcaat tttgcttaac aatttcaatt cctcatagtt atataagctt
     6541 ccgtcatttg aaaatactac atctcccaag tatacttgat catccacaat gaagaataag
     6601 cctactacaa tagactttcc gtcaacttca attctctttc ctcttggatg aacatagctt
     6661 attccaaact ctttactaat attggatagt aactctctaa ccttcttttc aaattcctta
     6721 gcgtcaactt ctggattcct tagacttgta tattttctca attcacttct aatacaatct
     6781 atgttatttt tctcacaaac tttttctacc ttatccatct catttcgtat gaactgtaat
     6841 attgaactga cattagttat ctctttacta ttccatagtg ttataattat tggtagaatg
     6901 tcctctgtta gatctttaca ataggcttct acaatttcct ttatgtcctc acttgttaac
     6961 gcgtcatcta gaggaattct gctctcctct attctccttc ttattgctaa atcagaaacc
     7021 ttgctgtaaa cctcagtagg cattgccata attatcggta tatcaagtcc tgcgttaatt
     7081 agcctgtgta ttagacttaa gtgataatcc cttatttcat caattaaaag tactagctta
     7141 ctcaaattct tcatatctct taacgcatta atcattccgt cgaagtttct ttcatagctc
     7201 aaacaataaa cccttagaaa gggattatta tatttattgc aaatttttag caaccaatcc
     7261 tcaaatttaa ctcccatcaa tcttttccaa aaagaatatc caagcttacc ctttatcttc
     7321 tgcagttcaa gtaaagcctt ttccctcaat tcgaattgag tagtcttagt ccagaattcc
     7381 tcatctatac tttgtttatt agctaagtct aagtaaattg ataagttatc agtttttgtt
     7441 atttcctcta ttttcttaag taacgtagtc tttcccatac caggttgtcc aacaactgat
     7501 gccacttcgt tatttcttac tatttctagt gtcttttcta aatattttct atatgttgga
     7561 cctaccagta taatgcttct agatgaccat gtagttacag ttactcttgg tatctcacaa
     7621 accatattta tctcctcctc ttaactattc cgtaagtaac gcctcttctc gtaaatccct
     7681 catcacctcc agctattaaa tcgtaatttt cctctacata ttttctaaat tttgagtaaa
     7741 actcttcctt agaaagtcct agttctatcc ttattctctc caatggcgca tatcctaaag
     7801 aatcccttat cctatcataa gcctcatcaa aatccttaga tgaaaaactc tttgattcaa
     7861 cgaatttctg taataggtca agcattttat gaatctcatc ccttagtatt ttcaactcgt
     7921 cttctatgtt tatactatct agcggttcaa aagtgatttt actcccattt tcaactcttc
     7981 ttatttttcc ctccttctct aactcctcga gtacatgtat gaggtttcta tccttaaact
     8041 tcctcttaat cttagataat gagaccggtt tctgtgaatc cttatattca ctcaatataa
     8101 gagcaaagac gtcatccttg ccaatcatgt taaaggtttt ggttctaaaa tgttcataag
     8161 gcttacagcc cttaatactg actttaggag tttaaaagaa gtcacgcaat tagaacgtat
     8221 tcataattat tttatttgat tcataagact tcctagttac tttttgtaac ttatctaatg
     8281 attggctatg aagaatatat gtatatatga agagagaatc tacataatat atctatatta
     8341 gtattaaaaa tgaaacaaga ttttcttaat aaactaaagc cttaattgtg gcaccaattt
     8401 ctgttgacga acttaatcta atccaagttg taggcttatc gataatattt attccacgct
     8461 ttaataccac gctatcgcta acttcatcat taatatcagc ctttaattgt aattcagctt
     8521 ctccgttaac tgatacgatt agtctattgg cattaggaac ataataccac ttactctccc
     8581 ttcccttgaa tttccctctt agctcaccat aactcctagg atcaaagata aaagtatcaa
     8641 cgtattctac ccaaatttca tgtgtatagc cctctttccc agtatcgatc ctagtggtat
     8701 aggtatctct gaaggataca aaaaacaatt ttggttttcc gtctggttcg gtagtgtaat
     8761 gaggatgtcc aacttgaacg aatgagtcat ctaaacctag aagtggcatt agtgaacctt
     8821 gaagaaaact aactttgtta acatcttctg tcacataaag ctcatctaaa ttaggtccaa
     8881 tgaacgattg taacatccat tttgaaacag tattcatttc aatgaagatt tgaaacctag
     8941 ggataagtgt gaagtctaat acatcattac tcctagccca agctccaata tcccctaaat
     9001 cctcaactct caccttttcc aaatcgtcga cgcttcttac catatataac ttaacaccag
     9061 aagaatcagc attaggagct actgcaaatg cgtcatgcat atttctatat gctccggttg
     9121 gtcttatagg aaagccagag tccttcttta agtccttaat taaaagttta tatcccttta
     9181 gtttccactc ttgatcgaat gcaaagaaat agacatcatt tccatgtgta gaagtgatgt
     9241 agaactcgtc tctagcctca ttgtaaaatc cccttattcc attgttacta tagtcaactt
     9301 gcattgggaa atcagatggt aaaatcttct taataccact aaagtcaacg tttagactcc
     9361 tatctattgg cgctacgaat ccttcacgtt ttaacccttt tagatcactc caaccagtga
     9421 agaggaacca gtgcttgtct cttttactat catagattac gtatggggtt cctactccac
     9481 ctttaatatc gctaaaggga gattttgggg gaagaattat tggtctgatc atactgaaaa
     9541 ataaccttta aagaataaaa tttttttatt atatatgtta taactcttct atttatcatt
     9601 gcccaaaaga tgtcttctta caaatattct aatatcctta acctttttga gagatttcaa
     9661 attcgttaca atactatcaa cttttgcatt atccttttct ctaatattta tactctcagc
     9721 ctcacttctc cctaactgat ttaaataata caatctttct ttttttagaa ttagactctt
     9781 ttttgataag gtatgtaaac gagaatctat tcttggacta tatacaaaat atcttttatt
     9841 ccacttaatt gaaaaaatcg ggttttgtat attgtaatat ctggataaat agtcgtaaag
     9901 taaaaatgag agtacgaaaa gtctagtctt gtcaatccct cccccatact tatatattgt
     9961 aaacaacgtt agggagtcaa cggtcatgtg ataagctact tcttgttctt tacataactt
    10021 ttctacgtta ctttctgcta ataacttaag aatataatag agagaaaccc aagacccata
    10081 tatttcgatt tcgtccaaag cctcctttaa gagttgttgt aatctattca ttaaactaac
    10141 ctctcttcta gttccactat tgccactatt aatcctgcat ggggaaatgc ttgaggaaag
    10201 ttacccctag gttcgcaagt gttctgatct aagtgttcag cgagtaataa tgatgatgta
    10261 gaacagttaa ttagcttctc aattactttt ttcgctctgt ctacttctcc taatctaata
    10321 taaacccggc ttaaccatgt cgagactagg gcaaaaggat gttttacatt tcccataaag
    10381 tcatccttat atcttagtaa taaaccatct gaaatcatta aatccctctc gatcttctca
    10441 aatgtcctca aaaatctagg atctttagca tctataaagc cgtatagcgg taaggtaagt
    10501 aaagcagaat ctactgaatt actcccgtaa tatctcgtaa aataacctaa cttttctgaa
    10561 tatccgttat caaaaacgtc ctttttaatt tcttcagcaa cattaatcca ttcctcagct
    10621 tcatttttat atcccaattc atttgcaagt ttgctagccc tatcgagagc tacccaatcc
    10681 ataaccttag tgtgcgtgaa atgctcctct actcctcttt gttcccataa atcagtactc
    10741 ttccatttcc aactcttctt agtccattcc gctattgcct ctatggccca ccatatttca
    10801 ctaatatatt ctgaatcttt acttgcatta taatattcgt atagtgcatt catataagca
    10861 ccttcaacat ccatttgtat ttgcatatac gctgcatttc caactcttac cggaaacgat
    10921 tttttatgac cttttagcca atctaggatt tcctctgctg gtggcgctgt tccatctatt
    10981 gtataaagtg gatgatcaaa acttttagac gaaggatcta tcatagcagt taggaatcct
    11041 a
//
