LOCUS       c00069_NZ_CALK..       13078 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CALKQY010000069.1 MAG: Hoylesella shahii isolate
            ERR589682_bin.108_CONCOCT_v1.1_MAG ERZ773040.338, whole genome
            shotgun sequence.
ACCESSION   c00069_NZ_CALK..
VERSION     c00069_NZ_CALK..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:06:46
            Original ID  :: NZ_CALKQY010000069.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13078
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13078
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2808:3078](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(2809..3078)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13078
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13078
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(162..338)
                     /locus_tag="ctg69_1"
                     /transl_table=11
                     /translation="MKKLVLAFVAIAAVSFASCNDKKNAPAANNDTAAVDTAAVDTAAA
                     AADSAAADTAAHM"
     CDS             complement(573..1055)
                     /locus_tag="ctg69_2"
                     /transl_table=11
                     /translation="MRTLDLNILIREFVFEEMTDADRQLLEQAKQATDNAYAKYSNFYV
                     GAAALLDDGSVVIGSNQENAAFPSGLCAERSAIFAAQSHYPTKSVNTLAIAARNENGFL
                     SNPISPCGACRQVMLEIEERYKHPVRILLYGTSRVFEISSVKDLLPLSFVDAHMHE"
     aSDomain        complement(591..986)
                     /aSDomain="TIGR01354"
                     /aSTool="tigrfam"
                     /description="cyt_deam_tetra: cytidine deaminase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg69_2_0001"
                     /evalue="7.70E-35"
                     /identifier="TIGR01354"
                     /label="ctg69_2"
                     /locus_tag="ctg69_2"
                     /protein_end="155"
                     /protein_start="23"
                     /score="117.9"
                     /tool="antismash"
                     /translation="QLLEQAKQATDNAYAKYSNFYVGAAALLDDGSVVIGSNQENAAFP
                     SGLCAERSAIFAAQSHYPTKSVNTLAIAARNENGFLSNPISPCGACRQVMLEIEERYKH
                     PVRILLYGTSRVFEISSVKDLLPLSFVD"
     PFAM_domain     complement(693..992)
                     /aSDomain="dCMP_cyt_deam_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00383.25"
                     /description="Cytidine and deoxycytidylate deaminase
                     zinc-binding region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg69_2_0001"
                     /evalue="1.80E-13"
                     /label="ctg69_2"
                     /locus_tag="ctg69_2"
                     /protein_end="121"
                     /protein_start="21"
                     /score="50.3"
                     /tool="antismash"
                     /translation="DRQLLEQAKQATDNAYAKYSNFYVGAAALLDDGSVVIGSNQENAA
                     FPSGLCAERSAIFAAQSHYPTKSVNTLAIAARNENGFLSNPISPCGACRQVMLEI"
     CDS             complement(1077..2387)
                     /locus_tag="ctg69_3"
                     /transl_table=11
                     /translation="MDTVFANVPSSTRSFWVYNRSQNNVRLSSVRLVGGNQHGFRVNVG
                     GTYLSAESGFQTSDLEVRKNDSVRVFVELTSPKATTEGMTLIEDKLVFSQLVAMEQRML
                     LRARSWKARQVYNLRIRRDTIISGESPIIVYGGIRVDSAATLTIAPGTKLFFHDKAGID
                     VYGRLLVKGTANANVTLRGDRLDKMFSYLPYSRVSGQWAGIRIYEHSYGNEFENMDLYG
                     AFDGLRLDSSDVSRPKLTLKASTIHNCQGYGILAEQCLMEMQNCQISNTQNDCVRINGC
                     KAALTHCTLAQFYPFATERGAALWITFDKYPLVTCLLQNCLITGYANDVVMLGKEEKEK
                     GVLITFRDSRIRMPKIDLPYVNATFDNIVYEQPTDTAFSPKNTFMTFDDKNLYYDFRLK
                     KGSGAINAGNALWTLPTDRLGKLRDAKPDLGAYEYAE"
     PFAM_domain     complement(1545..1985)
                     /aSDomain="Beta_helix"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13229.8"
                     /description="Right handed beta helix region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg69_3_0002"
                     /evalue="2.10E-06"
                     /label="ctg69_3"
                     /locus_tag="ctg69_3"
                     /protein_end="281"
                     /protein_start="134"
                     /score="27.8"
                     /tool="antismash"
                     /translation="YGGIRVDSAATLTIAPGTKLFFHDKAGIDVYGRLLVKGTANANVT
                     LRGDRLDKMFSYLPYSRVSGQWAGIRIYEHSYGNEFENMDLYGAFDGLRLDSSDVSRPK
                     LTLKASTIHNCQGYGILAEQCLMEMQNCQISNTQNDCVRINGC"
     CDS             complement(2809..3078)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg69_4"
                     /sec_met_domain="PF05402 (E-value: 1.3e-17, bitscore: 54.9,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.3e-09,
                     bitscore: 29.1, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKVGFNLRSICGEHIIVAEGKENIDFSKIISMNETSAYLWEAL
                     EDKEFTADTLANLLTEQYEVEFETALKDCSELLVNWQEAGIIEA"
     PFAM_domain     complement(2818..3036)
                     /aSDomain="PqqD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05402.14"
                     /description="Coenzyme PQQ synthesis protein D (PqqD)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg69_4_0003"
                     /evalue="8.80E-15"
                     /label="ctg69_4"
                     /locus_tag="ctg69_4"
                     /protein_end="87"
                     /protein_start="14"
                     /score="54.8"
                     /tool="antismash"
                     /translation="EHIIVAEGKENIDFSKIISMNETSAYLWEALEDKEFTADTLANLL
                     TEQYEVEFETALKDCSELLVNWQEAGII"
     CDS             complement(3114..3599)
                     /locus_tag="ctg69_5"
                     /transl_table=11
                     /translation="MSTNHSEIRELEFENARFLPEVIRFLDEGHTVTLGLKGYSMRPFL
                     EHKRDKALLSRPTTLQKGDAVLAEIAPGVFVLHRIVKIEGDDITLRGDGNLAIERCKKT
                     DVKGFALGFYRKGREKIDKTNSLKWRIYSALWTTLLPMRRYLLAFYSRIWIRLFGPI"
     CDS             complement(3575..4537)
                     /locus_tag="ctg69_6"
                     /transl_table=11
                     /translation="VFKVLAKLGVNLATLAQHALIRRRRATMSHNFIIAEHGVSIIFEN
                     ATPNDGTLIQSMDPFRVNDEPKNLLLKLFVTNDLQPISPEDTELIRDIDTGNGMTLVDV
                     LPSGGYQFHIRNVQGNLCCLLHTNKDFSICRCKLEGDFTMRNFGLNNALMLSYAFAGSF
                     QQTLLIHASLVRHQNKGYAFTAKSGTGKSTHVSLWLRYIPDCDLMNDDNPIVRVIDGKP
                     YIYGSPWSGKTPCYRNIKAELGSISRIDRAKENSVEQMRPIEAFASLLPSCSTMKWDKA
                     VFNNTVEIITKIIETSKVYTIHCLPNKDAALLCQQTIAK"
     CDS             complement(4592..4996)
                     /locus_tag="ctg69_7"
                     /transl_table=11
                     /translation="MKQLKKYFFAATFLLTLATTAQAKLVQTKVYIFGMAASFNDSTSY
                     ITDVQEVDAWINDKGNFLYSRENYSYQLRDFLQSQGFVNPTCITCFALSRKKAEKKYAT
                     LLKKNAAKGDANLRYLNAKDFKYAAVAPEK"
     CDS             complement(5090..5953)
                     /locus_tag="ctg69_8"
                     /transl_table=11
                     /translation="MRQLKITKSITNRESDSLDKYLQEIGHEELISVEEEVELAQRIKK
                     GDRKALEKLTKANLRFVVSVAKQYQNQGLSLQDLINEGNVGLIKAAEKFDETRGFKFIS
                     YAVWWIRQSILQAIAEQSRIVRLPVNQVGSVNKINRILNKFEQENERRPSINEIAEKTD
                     LPEDKIEDAIKVTGRHVSVDAPFMDGEDNSLLDMMANHDTPSVDNELVKESLRAEIAEA
                     LQFLNERERNVVEAFFGINQMEMTLEEIGDKYGLTRERVRQIKEKALRKLRNNTKNKML
                     KSYLGQ"
     PFAM_domain     complement(5132..5290)
                     /aSDomain="Sigma70_r4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04545.18"
                     /description="Sigma-70, region 4"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg69_8_0007"
                     /evalue="1.60E-17"
                     /label="ctg69_8"
                     /locus_tag="ctg69_8"
                     /protein_end="274"
                     /protein_start="221"
                     /score="62.9"
                     /tool="antismash"
                     /translation="ALQFLNERERNVVEAFFGINQMEMTLEEIGDKYGLTRERVRQIKE
                     KALRKLRN"
     aSDomain        complement(5132..5806)
                     /aSDomain="TIGR02937"
                     /aSTool="tigrfam"
                     /description="sigma70-ECF: RNA polymerase sigma factor,
                     sigma-70 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg69_8_0002"
                     /evalue="1.40E-35"
                     /identifier="TIGR02937"
                     /label="ctg69_8"
                     /locus_tag="ctg69_8"
                     /protein_end="274"
                     /protein_start="49"
                     /score="120.3"
                     /tool="antismash"
                     /translation="ALEKLTKANLRFVVSVAKQYQNQGLSLQDLINEGNVGLIKAAEKF
                     DETRGFKFISYAVWWIRQSILQAIAEQSRIVRLPVNQVGSVNKINRILNKFEQENERRP
                     SINEIAEKTDLPEDKIEDAIKVTGRHVSVDAPFMDGEDNSLLDMMANHDTPSVDNELVK
                     ESLRAEIAEALQFLNERERNVVEAFFGINQMEMTLEEIGDKYGLTRERVRQIKEKALRK
                     LRN"
     PFAM_domain     complement(5348..5551)
                     /aSDomain="Sigma70_r3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04539.18"
                     /description="Sigma-70 region 3"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg69_8_0006"
                     /evalue="2.00E-14"
                     /label="ctg69_8"
                     /locus_tag="ctg69_8"
                     /protein_end="202"
                     /protein_start="134"
                     /score="53.5"
                     /tool="antismash"
                     /translation="VNKINRILNKFEQENERRPSINEIAEKTDLPEDKIEDAIKVTGRH
                     VSVDAPFMDGEDNSLLDMMANHD"
     PFAM_domain     complement(5585..5788)
                     /aSDomain="Sigma70_r2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04542.16"
                     /description="Sigma-70 region 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg69_8_0005"
                     /evalue="2.10E-18"
                     /label="ctg69_8"
                     /locus_tag="ctg69_8"
                     /protein_end="123"
                     /protein_start="55"
                     /score="66.0"
                     /tool="antismash"
                     /translation="KANLRFVVSVAKQYQNQGLSLQDLINEGNVGLIKAAEKFDETRGF
                     KFISYAVWWIRQSILQAIAEQSR"
     PFAM_domain     complement(5810..5908)
                     /aSDomain="Sigma70_r1_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00140.22"
                     /description="Sigma-70 factor, region 1.2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg69_8_0004"
                     /evalue="3.90E-12"
                     /label="ctg69_8"
                     /locus_tag="ctg69_8"
                     /protein_end="48"
                     /protein_start="15"
                     /score="46.0"
                     /tool="antismash"
                     /translation="DSLDKYLQEIGHEELISVEEEVELAQRIKKGDR"
     CDS             complement(6137..6481)
                     /locus_tag="ctg69_9"
                     /transl_table=11
                     /translation="MTERDDDLLKHFFEEHKQELTDNGFSAQVMKKLPRSPIQTYNRLW
                     TFFCCMVGLAFILFTRGWELAIQVARNAGVLFFDALLGVNLSGFTPLVLFGGMLTIIGV
                     TIYNLSLLKD"
     PFAM_domain     complement(6200..6469)
                     /aSDomain="DUF5056"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16479.7"
                     /description="Domain of unknown function (DUF5056)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg69_9_0008"
                     /evalue="7.40E-19"
                     /label="ctg69_9"
                     /locus_tag="ctg69_9"
                     /protein_end="94"
                     /protein_start="4"
                     /score="67.9"
                     /tool="antismash"
                     /translation="DDDLLKHFFEEHKQELTDNGFSAQVMKKLPRSPIQTYNRLWTFFC
                     CMVGLAFILFTRGWELAIQVARNAGVLFFDALLGVNLSGFTPLVL"
     CDS             complement(6465..6977)
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 105.4;
                     E-value: 4.3e-32)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg69_10"
                     /transl_table=11
                     /translation="MAAEQHNRKAFNELVVRYQSPIRRFFLNQTLGNEALSDDLAQDTF
                     VKAYLNITKFRGDASFSTWLYRIAYNVFYDSTRNSKHTEDLETAEVSRRNAENSDTTVS
                     LDIYAALNTLNNYERTCLTLQLMEGQPIDKIAEIMGMAAGTVKSHLFRGKDKMTRYLKE
                     NGYDRKR"
     aSDomain        complement(6495..6950)
                     /aSDomain="TIGR02937"
                     /aSTool="tigrfam"
                     /description="sigma70-ECF: RNA polymerase sigma factor,
                     sigma-70 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg69_10_0003"
                     /evalue="7.80E-22"
                     /identifier="TIGR02937"
                     /label="ctg69_10"
                     /locus_tag="ctg69_10"
                     /protein_end="161"
                     /protein_start="9"
                     /score="75.6"
                     /tool="antismash"
                     /translation="AFNELVVRYQSPIRRFFLNQTLGNEALSDDLAQDTFVKAYLNITK
                     FRGDASFSTWLYRIAYNVFYDSTRNSKHTEDLETAEVSRRNAENSDTTVSLDIYAALNT
                     LNNYERTCLTLQLMEGQPIDKIAEIMGMAAGTVKSHLFRGKDKMTRYL"
     PFAM_domain     complement(6507..6662)
                     /aSDomain="Sigma70_r4_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08281.14"
                     /description="Sigma-70, region 4"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg69_10_0010"
                     /evalue="3.30E-12"
                     /label="ctg69_10"
                     /locus_tag="ctg69_10"
                     /protein_end="157"
                     /protein_start="105"
                     /score="46.0"
                     /tool="antismash"
                     /translation="DIYAALNTLNNYERTCLTLQLMEGQPIDKIAEIMGMAAGTVKSHL
                     FRGKDKM"
     PFAM_domain     complement(6738..6935)
                     /aSDomain="Sigma70_r2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04542.16"
                     /description="Sigma-70 region 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg69_10_0009"
                     /evalue="1.80E-12"
                     /label="ctg69_10"
                     /locus_tag="ctg69_10"
                     /protein_end="80"
                     /protein_start="14"
                     /score="46.9"
                     /tool="antismash"
                     /translation="VVRYQSPIRRFFLNQTLGNEALSDDLAQDTFVKAYLNITKFRGDA
                     SFSTWLYRIAYNVFYDSTRNS"
     CDS             complement(7017..7685)
                     /locus_tag="ctg69_11"
                     /transl_table=11
                     /translation="MKKYLLAFSMLFLVGVSVMDATPKHRHRHGAATVKVMEDSASSAI
                     HVYSDTTSFSDIDEDDANSIQVLAEYDDDDDIDNPLDLLKYLSRLGGPSGTILGVFIII
                     CSFLFLVAPFFVFVFILYYLIKRHNDRVKMSMKAMDMGQLPPTHNASSFSESDEVLWRK
                     GVKNTAVGLGLALMFIMFRAKPLVGVGLLVLCYGLGQVYMARVSRKKRENNDIDNHPEF
                     "
     PFAM_domain     complement(7077..7352)
                     /aSDomain="DUF6249"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF19762.1"
                     /description="Domain of unknown function (DUF6249)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg69_11_0011"
                     /evalue="6.80E-25"
                     /label="ctg69_11"
                     /locus_tag="ctg69_11"
                     /protein_end="203"
                     /protein_start="111"
                     /score="87.0"
                     /tool="antismash"
                     /translation="APFFVFVFILYYLIKRHNDRVKMSMKAMDMGQLPPTHNASSFSES
                     DEVLWRKGVKNTAVGLGLALMFIMFRAKPLVGVGLLVLCYGLGQVYM"
     CDS             7794..9197
                     /locus_tag="ctg69_12"
                     /transl_table=11
                     /translation="MVLPQDFITYTRALMGSERYDKMASALLEEPPVSLRLNPFKTLSG
                     ITEVCNADGQVPWASNGFYLSGRPNFTFDPLFHAGTYYVQEASSMFVAWIVSQLIHIPI
                     TMLDLCAAPGGKSTALRSVLPKGSLLFCNEPMPQRSNILAENVQKFGHPDMVVTNNFAA
                     DYRKSGLQFDVILADVPCSGEGMFRKDAGAIAEWSEANVEHCWRLQREIISDIWPCLKP
                     GGLLIYSTCTFNDKENERNVEWIEQEFGADFDLPPIPYEWNITGSIGSDIPACRFIPGS
                     SKGEGLFLCVLRKRHEHHLSREERIKRLSKNIPTKPKMPDIPQWLKADYDCSIRLINSN
                     IYAIPNQWVSVFDKACEALRIVHAGVGLATSKGKDLIPHPALALSIALADGAFTQCELD
                     YSSAIAFLRREAIALPNETPRGYVLVTHKDMPLGFVKNIGNRANNLYPQEWRIKSTHIP
                     QPQQIIKLK"
     PFAM_domain     7800..8063
                     /aSDomain="Methyltr_RsmF_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17125.7"
                     /description="N-terminal domain of 16S rRNA
                     methyltransferase RsmF"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg69_12_0012"
                     /evalue="4.20E-23"
                     /label="ctg69_12"
                     /locus_tag="ctg69_12"
                     /protein_end="90"
                     /protein_start="2"
                     /score="81.7"
                     /tool="antismash"
                     /translation="LPQDFITYTRALMGSERYDKMASALLEEPPVSLRLNPFKTLSGIT
                     EVCNADGQVPWASNGFYLSGRPNFTFDPLFHAGTYYVQEASSM"
     PFAM_domain     8106..8669
                     /aSDomain="Methyltr_RsmB-F"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01189.19"
                     /description="16S rRNA methyltransferase RsmB/F"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg69_12_0013"
                     /evalue="8.70E-35"
                     /label="ctg69_12"
                     /locus_tag="ctg69_12"
                     /protein_end="292"
                     /protein_start="104"
                     /score="120.3"
                     /tool="antismash"
                     /translation="TMLDLCAAPGGKSTALRSVLPKGSLLFCNEPMPQRSNILAENVQK
                     FGHPDMVVTNNFAADYRKSGLQFDVILADVPCSGEGMFRKDAGAIAEWSEANVEHCWRL
                     QREIISDIWPCLKPGGLLIYSTCTFNDKENERNVEWIEQEFGADFDLPPIPYEWNITGS
                     IGSDIPACRFIPGSSKGEGLFLCVL"
     PFAM_domain     9000..9149
                     /aSDomain="Methyltranf_PUA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13636.8"
                     /description="RNA-binding PUA-like domain of
                     methyltransferase RsmF"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg69_12_0014"
                     /evalue="1.20E-16"
                     /label="ctg69_12"
                     /locus_tag="ctg69_12"
                     /protein_end="452"
                     /protein_start="402"
                     /score="60.5"
                     /tool="antismash"
                     /translation="AIAFLRREAIALPNETPRGYVLVTHKDMPLGFVKNIGNRANNLYP
                     QEWRI"
     CDS             9341..9988
                     /locus_tag="ctg69_13"
                     /transl_table=11
                     /translation="LHLKSIIHELLWFLNGDTNVKYLQENGVRIWNEWADENGELGPVY
                     GHQWRSWPDYNGGHIDQIQGIVNALKNNPDSRRMIVSAWNVAEVDQMALPPCHCLFQFY
                     VADGKLSLQLYQRSADTFLGVPFNIASYALLTMMMAQVCGLQPGDFIHTTGDTHLYLNH
                     LEQAKEQLQRVPRALPKMVINPNVTSIFDFKYDDFTLEGYNPLPHIKAEVSV"
     PFAM_domain     9344..9985
                     /aSDomain="Thymidylat_synt"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00303.21"
                     /description="Thymidylate synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg69_13_0015"
                     /evalue="1.90E-103"
                     /label="ctg69_13"
                     /locus_tag="ctg69_13"
                     /protein_end="215"
                     /protein_start="1"
                     /score="345.4"
                     /tool="antismash"
                     /translation="HLKSIIHELLWFLNGDTNVKYLQENGVRIWNEWADENGELGPVYG
                     HQWRSWPDYNGGHIDQIQGIVNALKNNPDSRRMIVSAWNVAEVDQMALPPCHCLFQFYV
                     ADGKLSLQLYQRSADTFLGVPFNIASYALLTMMMAQVCGLQPGDFIHTTGDTHLYLNHL
                     EQAKEQLQRVPRALPKMVINPNVTSIFDFKYDDFTLEGYNPLPHIKAEVSV"
     aSDomain        9443..9985
                     /aSDomain="TIGR03284"
                     /aSTool="tigrfam"
                     /description="thym_sym: thymidylate synthase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg69_13_0004"
                     /evalue="5.50E-95"
                     /identifier="TIGR03284"
                     /label="ctg69_13"
                     /locus_tag="ctg69_13"
                     /protein_end="215"
                     /protein_start="34"
                     /score="315.9"
                     /tool="antismash"
                     /translation="ADENGELGPVYGHQWRSWPDYNGGHIDQIQGIVNALKNNPDSRRM
                     IVSAWNVAEVDQMALPPCHCLFQFYVADGKLSLQLYQRSADTFLGVPFNIASYALLTMM
                     MAQVCGLQPGDFIHTTGDTHLYLNHLEQAKEQLQRVPRALPKMVINPNVTSIFDFKYDD
                     FTLEGYNPLPHIKAEVSV"
     CDS             10009..10509
                     /locus_tag="ctg69_14"
                     /transl_table=11
                     /translation="MQINVIAAVAQNNAIGYQNKLIYWLPNDLKRFKALTTGHTIIMGR
                     NTFLSLPKGALPNRRNVVLSTTQTVFPGCDCFSSLHDALQSCDANEDVYIIGGAKLYNE
                     AIDIANRLLLTEVVDTPKEADAFFPCYDGWVQTACECHKKDEKHQFDYCFADYERPTTL
                     AID"
     PFAM_domain     10015..10485
                     /aSDomain="DHFR_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00186.21"
                     /description="Dihydrofolate reductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg69_14_0016"
                     /evalue="2.80E-48"
                     /label="ctg69_14"
                     /locus_tag="ctg69_14"
                     /protein_end="159"
                     /protein_start="2"
                     /score="163.7"
                     /tool="antismash"
                     /translation="INVIAAVAQNNAIGYQNKLIYWLPNDLKRFKALTTGHTIIMGRNT
                     FLSLPKGALPNRRNVVLSTTQTVFPGCDCFSSLHDALQSCDANEDVYIIGGAKLYNEAI
                     DIANRLLLTEVVDTPKEADAFFPCYDGWVQTACECHKKDEKHQFDYCFADYER"
     CDS             10545..11264
                     /locus_tag="ctg69_15"
                     /transl_table=11
                     /translation="MIIKISGMHHADDIKEASLLGVDLLGFDFIPQSKRYVRMISSQAG
                     IIPDFSEERLRTLSKHNNNLQPHSRRISRVGAFADDMPQNIVTRVYNYDLNYVQLNGDE
                     PAVTLENLRRTIDPDIQKSIRLIKKINITSIADLAKTTEYEGNADLLLFHITAEEAEYQ
                     ATGDKNSPLNQLLSVYSGITPFLISKPNAPFDTLLIKDIAHPLFAGIDLDTQFELENGR
                     KDMVALKSYVEAIRAFR"
     CDS             11303..11869
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1249:carbamoyl phosphate synthase small subunit
                     (Score: 115.3; E-value: 4.8e-35)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg69_16"
                     /transl_table=11
                     /translation="MNIVIIDNYDSFTYNLVHLIASLGANVTVLKNDNLDLVQLENFDK
                     IVLSPGPGLPEEAGKTMDVIKTYASIKPILGVCLGHQAIALAYGASLTNLPTVCHGLST
                     IGLNLGNDPIFKGLPAKVAMGRYHSWVVTRESVCPPLEITALSDDGLVMGIRHKHLKLH
                     GIQFHPESILTPEGKTIVNNWLYND"
     aSDomain        11309..11857
                     /aSDomain="TIGR00566"
                     /aSTool="tigrfam"
                     /description="trpG_papA: glutamine amidotransferase of
                     anthranilate synthase or aminodeoxychorismate synthase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg69_16_0005"
                     /evalue="1.50E-53"
                     /identifier="TIGR00566"
                     /label="ctg69_16"
                     /locus_tag="ctg69_16"
                     /protein_end="185"
                     /protein_start="2"
                     /score="179.4"
                     /tool="antismash"
                     /translation="IVIIDNYDSFTYNLVHLIASLGANVTVLKNDNLDLVQLENFDKIV
                     LSPGPGLPEEAGKTMDVIKTYASIKPILGVCLGHQAIALAYGASLTNLPTVCHGLSTIG
                     LNLGNDPIFKGLPAKVAMGRYHSWVVTRESVCPPLEITALSDDGLVMGIRHKHLKLHGI
                     QFHPESILTPEGKTIVNNWL"
     PFAM_domain     11312..11857
                     /aSDomain="GATase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00117.30"
                     /description="Glutamine amidotransferase class-I"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg69_16_0017"
                     /evalue="7.40E-46"
                     /label="ctg69_16"
                     /locus_tag="ctg69_16"
                     /protein_end="185"
                     /protein_start="3"
                     /score="156.4"
                     /tool="antismash"
                     /translation="VIIDNYDSFTYNLVHLIASLGANVTVLKNDNLDLVQLENFDKIVL
                     SPGPGLPEEAGKTMDVIKTYASIKPILGVCLGHQAIALAYGASLTNLPTVCHGLSTIGL
                     NLGNDPIFKGLPAKVAMGRYHSWVVTRESVCPPLEITALSDDGLVMGIRHKHLKLHGIQ
                     FHPESILTPEGKTIVNNWL"
     CDS             12402..12791
                     /locus_tag="ctg69_17"
                     /transl_table=11
                     /translation="LVEPHFNSRPAQNLFIFCSARVECNLLHRCHSLRLLALPNRLHAL
                     FLLLQFSKRRASVCFNVVDCVRRRDATHPHIRTILHFGESFRKASREQRHCQRQAHCIR
                     HYDCYVGIVVHSHSWKLRNFNHEPR"
ORIGIN
        1 atgaaattat gtgcatgagg gggaaggact tacaactggg ttttaggact gacccaataa
       61 aacctaaata agccaacaaa agcctagaaa cgcaaactac aaatacgaaa aaggcgcacc
      121 ctaaggatgc gccagttctc tcatttcact ttacgtagaa attacatgtg tgcagcagtg
      181 tcagcagcag ctgaatcagc agcggcagca gcagtgtcaa cagcagcagt gtcaacagca
      241 gcagtgtcat tgttagctgc gggagcattc tttttgtcgt tgcaagatgc gaaagatacg
      301 gctgcaatag ctacgaaagc caaaactaat tttttcattt tctttgcttt ttaaatctgt
      361 aaaacaatca tttgtttatt aaaacattgc aaaggtaggc atttttctaa taccacgaac
      421 tattttttat gatttttttt agccttatct tgtaactttt tcataaacac ctgcaataca
      481 acgaattaca aaagtgttaa aattgcattc gcaaaggttt ctttagacgt catccccctt
      541 tatcatccat ttcatcgtta caaagcgaag acttattcat gcatgtgtgc gtccacaaaa
      601 gaaagcggaa gaaggtcttt taccgatgaa atttcgaaaa cacgactcgt tccatagaga
      661 agaattctta cgggatgctt atatctttct tcaatctcta acatcacctg tctgcacgct
      721 ccgcaaggac taattggatt tgaaagaaag ccgttttcat tgcgagcagc tatggctaac
      781 gtgtttaccg actttgtggg ataatgtgat tgggcagcaa agatggccga acgttcggca
      841 cacaggcctg atggaaatgc tgcattttct tgatttgaac caataaccac gcttccatca
      901 tctaacaatg ctgctgcgcc cacgtagaaa ttggaatact tggcataggc attatctgta
      961 gcctgttttg cctgctcaag caattggcgg tcggcatcag tcatttcttc gaaaacaaat
     1021 tcgcgaataa ggatgttaag gtctaatgtt ctcatattat ataatgtgat tgttttttat
     1081 tctgcatact cataagcccc taagtctggt tttgcgtcgc gcaacttacc caatctatca
     1141 gtgggtaaag tccacaatgc attgccagca ttaattgccc cactaccctt tttcaaccta
     1201 aaatcatagt aaaggttctt gtcatcgaac gtcataaaag tatttttagg cgagaatgcg
     1261 gtatctgtgg gctgttcgta aacaatgttg tcgaacgtgg cattaacata aggcaggtct
     1321 attttaggca ttcggatacg actatctcta aatgtaatca acaccccttt ttctttttct
     1381 tcctttccta gcatcaccac atcgttggca taacctgtta taagacaatt ctgaagcaag
     1441 caggtaacca gcgggtactt gtcaaacgtt atccacaaag ccgctcccct ttctgttgca
     1501 aaaggataaa actgcgccag ggtgcagtgt gttagtgcgg ctttacaacc atttatccgc
     1561 acacaatcgt tctgtgtatt ggatatttga cagttttgca tctccatcag gcattgttct
     1621 gccaatatcc catagccctg acaattatga attgttgatg cttttaaggt aagtttcgga
     1681 cgtgaaacgt ctgaagagtc taatcttagc ccatcgaaag caccataaag gtccatgttt
     1741 tcaaattcat tgccatacga atgttcgtaa atgcgtatac ctgcccattg tccactcaca
     1801 cgactgtatg gcagatagct gaacatttta tccaatctat cacctctcag tgtcacattg
     1861 gcattggccg ttcccttcac caacaagcgc ccatacacat ctataccagc cttatcatga
     1921 aaaaacaact ttgtaccagg ggcaatagtt agtgttgctg cactatctac acgtatgcca
     1981 ccataaacaa ttatcggact ttcgcctgat ataatggtgt ctctacgtat gcgtaaattg
     2041 tatacttggc gagctttcca gctacgtgca cgtagcaaca tacgctgttc catagccacc
     2101 aactgactaa aaaccaattt atcttcaatc aaagtcatgc cttcggtggt ggcttttggg
     2161 gaagtgagct ctacaaaaac ccgcacacta tcgttcttcc tcacttctaa atcacttgtt
     2221 tgaaagcccg attcagcact cagataagta ccgccaacgt ttacccgaaa gccatgttga
     2281 ttgccaccca ctaaccttac gctagataag cgtacattat tttgggagcg attatacacc
     2341 caaaaactac gcgttgagct aggaacgttg gcaaaaacag tgtccatgtc taccgtatcg
     2401 acagaaaaat aaagtggaga gaccgaagaa gatgttgaaa aatcttcatc ggagcacgat
     2461 ataaacaaac tgatgatagc gacaataaat agggtgtact ttactttcat ataccttata
     2521 acgtctaaca agaaaaaata ttgttggtag agacaaaaga aatacgctgc gccttgctgt
     2581 atttcctttt atctatggat gaagattgtg tatcagtctc ttgataaaga aaatcatgag
     2641 tagatagaca caccgcttgt ccttgtgaat aattgggttt tctaaagcgc aaagaaaaga
     2701 aataagcaaa caaaagaaaa gctagttcta aaaaacacct tgatgtattt tagaactagg
     2761 attacagatg taaactaatt aggttgtcaa caattatcgt tgggcagctt aagcctcgat
     2821 aattccggcc tcttgccaat taacaagcag ttcgctgcag tctttaagag ccgtctcaaa
     2881 ctccacctcg tattgctcgg taagcaagtt tgccaaagtg tcagccgtaa actctttatc
     2941 ttctaaagct tcccaaagat aagcagaggt ttcgttcatg ctgataatct tgctaaagtc
     3001 gatattttct ttaccttcag ccacaataat atgctcgcca cagatggagc gcaaattaaa
     3061 tcctactttt tttttcataa tccattatac tgtgtttacg tacgtttgta cccttagatt
     3121 gggccaaaca gacgtatcca aattcgtgag taaaaagcca acagatatct acgcatcggc
     3181 aacaaggttg tccatagggc cgaataaatg cgccatttaa gactgttggt tttgtctatt
     3241 ttctctcttc cttttctata aaagcccaaa gcgaacccct taacatcagt ctttttgcac
     3301 cgttcgatgg ccaaattgcc atcgcctcgt agggttatgt catccccttc aatttttact
     3361 atacgatgca acacaaaaac accaggagca atctcagcca acaccgcatc acctttttgt
     3421 agcgttgtgg gtctgctaag caaagcctta tctcgcttat gctctaagaa agggcgcatg
     3481 ctatatccct ttaacccaag ggtgacagta tgtccttcat ccaagaagcg tattacttcg
     3541 ggcaagaacc gagcgttttc aaactcaagt tctcttattt cgctatggtt tgttgacata
     3601 acagcgctgc gtctttattg ggtaagcaat gaatggtgta tactttagag gtctctatta
     3661 tcttagtgat gatttcaaca gtgttattaa acacggcttt atcccatttc attgtagaac
     3721 acgacggaag caacgaagca aaagcctcga taggcctcat ctgttccaca ctgttttctt
     3781 tggctcggtc gatacgcgag attgaaccaa gttcggcctt tatgttacga tagcaaggcg
     3841 ttttaccact ccacggacta ccatatatat agggttttcc atcgatgacg cgaacaatgg
     3901 gattatcatc gttcatcaag tcgcaatcag gaatatagcg taaccacaga ctaacgtgag
     3961 tactttttcc tgttccactc ttagctgtaa aagcatagcc cttattttga tgtcgcacga
     4021 gcgaggcatg gataagcaac gtctgttgaa acgaacctgc aaaagcatac gatagcatca
     4081 atgcattatt taaaccaaag ttacgcatgg tgaaatcacc ctctaattta catctgcaaa
     4141 tcgagaaatc tttgttcgta tgaagcaggc aacataaatt gccttgaaca tttctgatat
     4201 gaaattggta accgcccgat ggcaatacgt ctactaaggt catgccgttg cctgtgtcga
     4261 tatcccttat cagctctgta tcttctggcg aaataggctg caagtcgtta gtaacaaaca
     4321 gcttcaaaag caagtttttc ggttcatcat tcaccctaaa agggtccatc gactgtataa
     4381 gtgttccatc attgggagtt gcattttcaa aaataatgct caccccatgt tctgcgatta
     4441 taaaattatg actcatcgtt gctcttcttc tccgtataag tgcgtgctgt gccagcgttg
     4501 caaggttaac accaagcttc gccaaaacct taaacacaac atcccaattt atttaccagc
     4561 acatcaattg agggaattta gactagtggc attatttctc gggtgctacg gctgcgtatt
     4621 taaaatcttt agcgttgagg tagcgcaaat tagcgtcgcc tttagcagca tttttcttta
     4681 acagcgtggc atatttcttt tcggctttct ttcgcgaaag ggcaaagcaa gtgatgcaag
     4741 tgggatttac aaagccttgc gactgcaaaa agtcgcgaag ttgatacgaa taattctccc
     4801 tactatagag gaaatttccc ttatcgttaa tccaagcatc aacctcttgc acatcggtaa
     4861 tgtaagatgt tgagtcgtta aacgaagcag ccattccaaa gatataaacc ttggtttgca
     4921 ccagtttggc ttgggccgtt gtggccaatg tcagcaagaa tgttgctgca aaaaaatatt
     4981 tttttaattg tttcatcatt atttatatgg cagaatcact gcttttatcc tattgagaga
     5041 ggccacacta gccccactct accctattta ttagtgcagc gcactcgctt tactgtccca
     5101 gataagactt tagcattttg ttcttagtgt tgttcctgag ttttcgaagg gccttttctt
     5161 ttatttggcg cactctttcg cgcgttagtc cgtacttatc cccaatttct tcgagcgtca
     5221 tttccatttg attgataccg aagaaagcct caacaacgtt acgctcgcgt tcatttaaga
     5281 attgcagagc ctctgcaatc tcagctcgca acgactcttt caccaattcg ttgtcaacac
     5341 ttggagtgtc gtgattggcc atcatgtcaa gcaagctatt gtcttccccg tccataaatg
     5401 gtgcatccac ggaaacatgc ctgccagtta ccttgatagc atcctcaatc ttgtcttctg
     5461 gcaagtcggt tttctctgct atctcgttaa tgctgggcct gcgttcgttt tcttgttcga
     5521 acttattaag tatcctatta attttattta ccgagcccac ttgatttact ggcaaacgaa
     5581 caatgcgact ttgttctgca atagcttgca aaatgctttg ccttatccac cacacggcgt
     5641 aagaaataaa cttaaaacca cgcgtttcgt caaacttttc agcagctttt atgagtccca
     5701 cattaccttc gttaatgaga tcttgtaggc taagtccctg gttttgatat tgtttggcaa
     5761 cagacacaac aaatcgcaag ttggctttgg ttagcttctc caaggctttt ctgtctcctt
     5821 ttttgatgcg ttgtgccaat tcaacttcct cttccacaga gattagttct tcatgtccaa
     5881 tctcctgcag gtacttgtcc agcgagtcac tctccctgtt cgttatcgat ttcgtgattt
     5941 tcagctgtct cattaagcgt tacttttata tgcttgtatg caaatttaat gactttgaag
     6001 cacattcaca aatctttttg cctttttttg cttatctatc tacatcttct ttatacacag
     6061 cagaaaaggc agacaatttt attgcctgcc tttagtgctt tttgtgttgc ctacttggta
     6121 tgcaacaacg atgttgtcag tctttaagca aactgagatt gtaaattgtt acgccaataa
     6181 tggtgagcat acctccgaac aaaactaaag gtgtaaagcc cgaaagattc acaccgagaa
     6241 gggcgtcgaa gaacaacacg cccgcatttc tagccacttg tattgccaat tcccaacctc
     6301 ttgtaaacaa tataaaggcc aacccaacca tacaacagaa gaatgtccac agcctgttat
     6361 aggtttggat gggcgaacga ggcagcttct tcatcacttg tgcagagaag ccgttgtctg
     6421 ttaattcttg tttgtgctct tcaaagaagt gtttcaacaa gtcgtcatct ctttctgtca
     6481 tatccatttt cttttaagta tcgtgtcatt ttatctttac ccctgaacaa atgcgacttc
     6541 acggtacctg cagccatgcc cattatctcg gcgattttgt cgattggctg gccttccatc
     6601 agctgcaaag ttaaacaagt tcgttcgtaa ttattcagcg tattcaatgc agcatagatg
     6661 tcaagcgaga cagttgtgtc ggaattttct gcgtttcgcc tgctcacctc cgccgtttct
     6721 aagtcttcgg tgtgtttact gttacgtgtg ctatcgtaaa acacattgta agcaatacga
     6781 tagagccatg tcgagaaaga cgcatcgccc ctgaatttag tgatattgag ataagctttc
     6841 acgaatgtat cctgagccag gtcgtcgcta agcgcttcgt ttcccaacgt ttgattgaga
     6901 aagaaacgcc taatgggcga ctgatacctc acaaccagct cgttaaaagc ttttcggttg
     6961 tgttgttcag ccgccatggc aactagggta ttatcgttta gcgcagtcac gtttatttaa
     7021 aattcaggat gattatcaat atcgttgttt tcgcgttttt tacgagaaac gcgtgccata
     7081 tacacctgcc cgagtccgta gcagagtacc aatagaccca cgcccaccaa tggcttggca
     7141 cgaaacatta taaacatcaa agctaaaccc agtccgacag ccgtattctt cacacctttt
     7201 ctccacaaca cctcatcgct ttctgaaaag gaggaagcat tatgtgttgg tggcaactgc
     7261 cccatatcca ttgctttcat tgacattttc acacggtcgt tgtgtcgttt tatcaaatag
     7321 tataagataa aaacaaatac aaagaaaggt gcaaccaaga agagaaaact gcaaatgata
     7381 ataaagacac ctaagatagt tccgctggga ccacctaacc ttgaaagata ttttaagagg
     7441 tcaagaggat tatcgatgtc atcatcatca tcatactctg caagcacctg gatactatta
     7501 gcatcatcct catctatatc gctaaaagac gtggtatcag aatacacatg aatggcagaa
     7561 gaagcactgt cttccataac cttaacagtg gctgcgccgt ggcgatgtcg gtgcttaggg
     7621 gtggcatcca taaccgagac tccgactaga aacagcatgg aaaacgccaa aagatatttc
     7681 ttcattgtgt tgttgtttta tcgtttttac gtatataaga cgcaaacaaa cacgatttag
     7741 ttgcagagga tgaaaaaaaa acatatattt gtactcgcta aagacgaatt tacatggtgc
     7801 taccacaaga tttcatcact tacacacggg ctttgatggg cagcgaacgc tatgataaaa
     7861 tggcttccgc gttactcgaa gaacctcccg tgagcctaag attaaacccg tttaaaacct
     7921 taagcgggat caccgaggta tgcaatgctg atggtcaagt gccctgggcc agcaatggct
     7981 tttatctgtc tgggcgcccc aacttcactt tcgaccctct atttcatgca ggcacatatt
     8041 atgtgcaaga ggcatcgtcg atgtttgtgg catggatagt tagccaattg atacatatcc
     8101 ccattacaat gctcgaccta tgtgctgccc ctggcggtaa gtctacagct ttaaggagcg
     8161 ttctgccgaa aggaagcttg ctcttctgca acgagccaat gccacaaaga tcaaacatat
     8221 tggctgaaaa cgtccagaag tttggacacc ccgacatggt ggttacaaac aattttgctg
     8281 cagactaccg caaaagtggc ttgcaattcg atgtcatctt agccgatgtg ccttgctcgg
     8341 gcgagggtat gttcagaaaa gatgctggtg ctattgccga atggagcgaa gcaaatgtgg
     8401 aacattgctg gcgattgcaa cgggaaatta tttccgacat ttggccctgc cttaagcctg
     8461 gcggattact gatttactct acttgcactt ttaacgacaa agagaacgaa cgcaacgtgg
     8521 agtggattga acaagagttt ggtgccgatt tcgacctccc gcccattcct tacgaatgga
     8581 acatcactgg tagcattggc tcagacattc ctgcttgtag gtttatccca ggctcatcca
     8641 agggagaagg ccttttctta tgcgtgctta gaaaaaggca cgaacaccac ttgtctcgcg
     8701 aagagcgaat aaaacgccta agcaaaaaca taccgacaaa gcctaaaatg cccgatattc
     8761 cacaatggct taaagcagat tatgattgct cgatacgcct aataaacagc aatatctatg
     8821 ccattcccaa ccaatgggtt agcgtattcg ataaagcttg tgaggcttta cgcatcgtcc
     8881 acgcgggagt gggattggcc acctctaagg gtaaagacct tattccgcac cctgccctag
     8941 ccctctccat tgctttagct gatggtgctt ttacccaatg cgagctagat tactcctcag
     9001 ccatcgcttt tttaaggcgc gaggccatcg ctcttcccaa cgaaacgcca cgtggatacg
     9061 tactggtaac ccataaagac atgcctttgg gctttgtaaa aaacataggc aaccgcgcca
     9121 acaacctcta tccacaagag tggcgcataa aaagcacgca cataccgcaa cctcaacaga
     9181 ttataaaatt aaaatgaaac aatatctaga cttgcttcaa cgcatcgtaa ccgagggctc
     9241 gcgcaaggaa gatcgcacta gaacgggaac cttaagtgtt ttcggacacc aaatgcgttt
     9301 taacctcgca gagggctttc cgttgctcac tacgaagaag ttgcacctca aatccattat
     9361 tcacgaattg ctttggtttc tcaatggaga cacaaacgtg aaatatcttc aagaaaatgg
     9421 tgtgagaatt tggaacgaat gggccgacga aaacggcgaa ctgggccctg tttatgggca
     9481 tcaatggcgt tcttggcctg attataatgg tggacacatc gaccaaattc aaggcattgt
     9541 gaatgctttg aagaataatc ccgactcgcg acgcatgata gtgagcgcat ggaatgtggc
     9601 agaagttgac caaatggctc tccccccctg ccattgctta ttccaattct atgttgccga
     9661 cggcaaatta agcttgcaat tgtatcagcg ttcggccgat acgttcctcg gtgtgccatt
     9721 taacatcgcc tcgtatgcac tcttaaccat gatgatggcc caggtttgcg gtctgcaacc
     9781 tggtgacttt atccacacaa caggcgacac gcatctttac ctaaaccatc tagaacaagc
     9841 taaagagcag cttcagcgcg tccctcgagc attgcccaag atggtaatta accctaatgt
     9901 aacaagtatt ttcgacttta aatacgacga tttcaccctc gaaggttaca accctcttcc
     9961 tcatatcaag gccgaagtat cggtgtaagc ttcttaatac atcaagttat gcagataaac
    10021 gttattgctg ctgtggcgca aaacaatgcc attggctatc aaaacaaact gatatactgg
    10081 ttgcccaacg atttaaagcg cttcaaggcc cttaccactg gccacactat tatcatgggt
    10141 cgaaacacct ttctttcgct acccaaaggg gcattgccta atagaaggaa tgtggtgttg
    10201 agcaccactc aaaccgtttt ccctggctgc gactgttttt cttccttaca cgatgcatta
    10261 caaagttgcg atgctaacga agacgtatat ataataggtg gcgctaagct ttataacgaa
    10321 gctatagaca ttgctaatag acttctttta accgaagtag tcgatacgcc taaggaagca
    10381 gatgcgttct ttccatgtta cgatggctgg gtgcaaactg cttgcgaatg tcataagaaa
    10441 gacgagaagc atcagtttga ctattgtttt gccgactacg aacgaccgac aacgctcgct
    10501 atcgactaat ctcaaacaca ctaaatacat ttacacgcaa acgtatgata atcaagatta
    10561 gtggcatgca tcatgccgac gacatcaaag aggcttcgct tttgggcgtc gaccttcttg
    10621 gattcgactt cattccccaa agcaaacgat acgtaaggat gatctcatca caagcaggta
    10681 tcatccccga cttcagcgaa gagcgtcttc gcacgcttag taagcataat aacaacctac
    10741 aaccacattc acgtaggatt agtcgtgtgg gcgcttttgc cgatgatatg cctcaaaaca
    10801 ttgtaacacg cgtatataac tacgacctta attatgtgca acttaacgga gacgaacctg
    10861 ctgtgacgct cgaaaaccta cgacgcacta tcgaccccga catacaaaag agcatcagac
    10921 ttattaaaaa gattaacatc acctcgatag ccgacctggc caaaaccacc gaatacgagg
    10981 gtaatgccga cctgctactt tttcatatca ctgctgaaga agccgaatat caagccactg
    11041 gcgacaaaaa ttcgccactc aaccaactgc tttctgtata ctctggcatc acaccttttt
    11101 taataagcaa acccaatgcc cccttcgaca ccttattaat taaggacatt gctcacccct
    11161 tgtttgcagg tatcgatctt gatacgcagt tcgaattaga aaatgggcgt aaagacatgg
    11221 tcgcattgaa aagttatgta gaagccatta gagcctttag atgataacat acacaacaaa
    11281 aggcgtaaca caaaagaaaa ccatgaatat agttatcatc gacaactacg actcattcac
    11341 atacaatctt gtacatctca ttgcaagttt gggggcaaat gtaacggtat tgaagaacga
    11401 taatttggat ctggtccagc tagaaaactt tgataaaatt gtgcttagcc caggtcctgg
    11461 ccttcctgaa gaagcaggca agactatgga cgtgataaaa acctatgcct ccatcaaacc
    11521 catactggga gtttgtcttg gtcatcaagc catagccttg gcttatggcg ccagtcttac
    11581 caatctccct acagtctgtc atggtctttc aaccattggg ttaaaccttg gtaacgaccc
    11641 cattttcaaa ggattacccg ccaaagtggc catgggtaga tatcatagtt gggtcgtaac
    11701 acgcgaaagc gtctgtcctc cattagagat aacagcccta agtgacgacg gattggtgat
    11761 gggcatccgc cacaagcact taaaattgca cggcatacag tttcatcccg aaagcatttt
    11821 aacgcccgag ggcaaaacca tcgtcaacaa ctggttatat aatgactaat tacttttcat
    11881 caaaaaacaa ctcagacaag aatataacta gctattaata aaaagattat cgacaatcat
    11941 ataagcaaaa ataaagcaat taattaccaa catcaattta atattttatt caaaaaagca
    12001 tatttcgtct ttaaaacgag gttatttata aaataaatca tacctttgta ttaaaataaa
    12061 ggactttatg aataccacga gccccactat catgacatcc aaacactaaa acaaccattt
    12121 aatggagcaa ctggtataaa aaccttaagc ttgcctgaac ttatgacgag aaaacaacaa
    12181 cactacaaat ggcgcctagt tggaaatgta attctaacct tggtaatgtt taccgcaatc
    12241 tcggtaatcc ttaaacctgt gttcatgttc tacaatcaca gttctttcag tgattgtact
    12301 ttgagcgatt atatggccgt tatttggcac ggcctgccca tggacttatc agtagctggt
    12361 tatttcacca tcatccctgc cctactggca ctaatttcca tttggttgaa ccccacttta
    12421 attcgcggcc tgcacagaac ctatttattt tttgcagcgc tcgtgttgag tgtaatctat
    12481 tgcacagatg ccattctcta cgattattgg cacttccgaa tagactccac gccctttttc
    12541 tacttcttca gttctccaaa agacgcgcta gcgtctgttt caacgtggtg gattgtgttc
    12601 ggcgtcgcga tgctactcat cctcatatcc gcactattct tcattttggt gaaagcttta
    12661 ggaaggcttc ccgagagcaa aggcattgcc aaagacaggc tcattgcatc cgccattatg
    12721 attgttatgt tgggattgtt gttcattccc attcgtggaa gcttaggaac ttcaaccatg
    12781 aacctaggta gagtgtactt cagcgaaaac caaaaactaa accacgcggc cattaatccc
    12841 tgctttagtt tactcacttc gctaattaac gacgaaaaca ctcaagacca atatcgtttt
    12901 ttcaccgaaa cagaggccaa taagctattc gcaaaaatca gggacaacag tgctaaagga
    12961 ggaactgatg cggtgtttaa aatgctaaat accaacaagc ccaatatcat tttggtggta
    13021 ttagaaagct tttcagcgca tatcatgaaa tctatgggcg gtacacctaa cgtggctg
//
