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Overview
1.1
1.2
1.3
1.4
1.5

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP007597.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1 | arylpolyene | 77,712 | 121,332 | APE Vf | Other | 45%
Region 2 | NRPS | 2,167,165 | 2,211,112 | streptobactin | NRP | 23%
Region 3 | lanthipeptide-class-ii | 2,293,746 | 2,316,640 |
Region 4 | RRE-containing,RiPP-like | 3,019,441 | 3,044,470 |
Region 5 | LAP | 3,723,033 | 3,745,131 |

NZ_CP007597.1 - Region 1 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 77,712 - 121,332 nt. (total: 43,621 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002008.1 |  | 0.29 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000836.1 |  | 0.28 | Other | APE Ec | Escherichia coli CFT073
BGC0002000.1 |  | 0.26 | Polyketide | setomimycin | Streptomyces aurantiacus JA 4570
BGC0000632.1 |  | 0.25 | Terpene, Saccharide | brasilicardin A | Nocardia terpenica
BGC0000231.1 |  | 0.24 | Polyketide | griseusin | Streptomyces griseus
BGC0000889.1 |  | 0.24 | Other | bagremycin A, bagremycin B | Streptomyces sp. WK-5344
BGC0001343.1 |  | 0.23 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15
BGC0000236.1 |  | 0.23 | Polyketide | kinamycin | Streptomyces murayamaensis
BGC0002012.1 |  | 0.23 | Polyketide | julichrome Q3-3, julichrome Q3-5 | Streptomyces afghaniensis 772
BGC0000234.1 |  | 0.23 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002008.1 |  | 0.63 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000836.1 |  | 0.62 | Other | APE Ec | Escherichia coli CFT073
BGC0002000.1 |  | 0.59 | Polyketide | setomimycin | Streptomyces aurantiacus JA 4570
BGC0000632.1 |  | 0.58 | Terpene, Saccharide | brasilicardin A | Nocardia terpenica
BGC0000231.1 |  | 0.58 | Polyketide | griseusin | Streptomyces griseus
BGC0000889.1 |  | 0.57 | Other | bagremycin A, bagremycin B | Streptomyces sp. WK-5344
BGC0001343.1 |  | 0.57 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15
BGC0000236.1 |  | 0.56 | Polyketide | kinamycin | Streptomyces murayamaensis
BGC0002012.1 |  | 0.56 | Polyketide | julichrome Q3-3, julichrome Q3-5 | Streptomyces afghaniensis 772
BGC0000234.1 |  | 0.56 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP007597.1 - Region 2 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,167,165 - 2,211,112 nt. (total: 43,948 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001615.1 |  | 0.32 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0001185.1 |  | 0.27 | NRP | bacillibactin | Bacillus velezensis FZB42
BGC0001399.1 |  | 0.25 | NRP | fellutamide B | Aspergillus nidulans FGSC A4
BGC0000401.1 |  | 0.25 | NRP | paenibactin | Paenibacillus elgii B69
BGC0001302.1 |  | 0.25 | Other | lomofungin | Streptomyces lomondensis
BGC0001132.1 |  | 0.25 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001825.1 |  | 0.25 | NRP | xenematide | Xenorhabdus nematophila AN6/1
BGC0001833.1 |  | 0.24 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001128.1 |  | 0.23 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001131.1 |  | 0.23 | NRP | ambactin | Xenorhabdus miraniensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001615.1 |  | 0.65 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0001185.1 |  | 0.60 | NRP | bacillibactin | Bacillus velezensis FZB42
BGC0001399.1 |  | 0.59 | NRP | fellutamide B | Aspergillus nidulans FGSC A4
BGC0000401.1 |  | 0.58 | NRP | paenibactin | Paenibacillus elgii B69
BGC0001302.1 |  | 0.58 | Other | lomofungin | Streptomyces lomondensis
BGC0001132.1 |  | 0.58 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001825.1 |  | 0.58 | NRP | xenematide | Xenorhabdus nematophila AN6/1
BGC0001833.1 |  | 0.57 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001128.1 |  | 0.57 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001131.1 |  | 0.57 | NRP | ambactin | Xenorhabdus miraniensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 2167164 - 2211112:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (ser)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_1888: dhb
  Search NORINE for peptide: strict or relaxed
  AMP-binding (39..444): dhb
  NRPSPredictor2: dhb
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aromatic
    Large clusters prediction:
      dhb, sal
    Small clusters prediction:
      dhb, sal
    Single AA prediction:
      dhb
  Stachelhaus prediction details:
    Stachelhaus sequence:
      PMPgQGVVNK
    Nearest Stachelhaus code:
      dhb
    Stachelhaus code match:
      90% (moderate)
ctg1_1891: ser
  Search NORINE for peptide: strict or relaxed
  AMP-binding (475..861): ser
  NRPSPredictor2: ser
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      ser
    Single AA prediction:
      ser
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHFSLVDK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      100% (strong)

NZ_CP007597.1 - Region 3 - lanthipeptide-class-ii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,293,746 - 2,316,640 nt. (total: 22,895 nt) Show pHMM detection rules used
lanthipeptide-class-ii: cds(LANC_like and DUF4135)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Lanthipeptides
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lanthipeptide-class-ii | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000528.1 |  | 0.27 | RiPP | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0001579.1 |  | 0.25 | RiPP | duramycin | Streptomyces cinnamoneus
BGC0001576.1 |  | 0.25 | RiPP | divamide A | Prochloron didemni
BGC0000503.1 |  | 0.23 | RiPP | cinnamycin | Streptomyces cinnamoneus
BGC0001364.1 |  | 0.23 | RiPP | cinnamycin B | Actinomadura atramentaria DSM 43919
BGC0001210.1 |  | 0.19 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0001407.1 |  | 0.18 | RiPP | bicereucin | Bacillus cereus SJ1
BGC0000527.1 |  | 0.18 | RiPP | mersacidin | Bacillus sp. HIL-Y85/54728
BGC0000517.1 |  | 0.16 | RiPP | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0001778.1 |  | 0.15 | Other | showdomycin | Streptomyces showdoensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000528.1 |  | 0.61 | RiPP | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0001579.1 |  | 0.59 | RiPP | duramycin | Streptomyces cinnamoneus
BGC0001576.1 |  | 0.58 | RiPP | divamide A | Prochloron didemni
BGC0000503.1 |  | 0.56 | RiPP | cinnamycin | Streptomyces cinnamoneus
BGC0001364.1 |  | 0.56 | RiPP | cinnamycin B | Actinomadura atramentaria DSM 43919
BGC0001210.1 |  | 0.51 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0001407.1 |  | 0.50 | RiPP | bicereucin | Bacillus cereus SJ1
BGC0000527.1 |  | 0.49 | RiPP | mersacidin | Bacillus sp. HIL-Y85/54728
BGC0000517.1 |  | 0.47 | RiPP | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0001778.1 |  | 0.44 | Other | showdomycin | Streptomyces showdoensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Lanthipeptide predictions
Lists the possible core peptides for each biosynthetic enzyme, including the predicted class. Each core peptide shows the leader and core peptide sequences, separated by a dash.

#### Lanthipeptide(s) for ctg1_1970 - Putative Class II

ctg1_1969 leader / core peptide
  MELNDNVVAG - WLNGADDhaVDGCENPAGDhaLFIYGQDADhbDAALDhbAMAPDhbMVDhbGGDhbGNC Dhb Dhb DhbMDhaVINHCMC C
allorf_2303308_2303376 leader / core peptide
  MARRGRLAIRSDDGQAA - FLGC Dhb
allorf_2314479_2314571 leader / core peptide
  LLHSIAPA - IDADhaEAIQPQRDhaMRCRKGGARI

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
Lanthipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

ctg1_1969 - Class II
  Cleavage pHMM score: -6.00
  RODEO score: 0
  Monoisotopic mass: 5688.5 Da
  Molecular weight: 5692.4 Da
  Number of bridges: 5
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    5710.4 Da N = 1
    5728.4 Da N = 2
    5746.4 Da N = 3
    5764.5 Da N = 4
    5782.5 Da N = 5
    5800.5 Da N = 6
allorf_2303308_2303376 - Class II
  Cleavage pHMM score: -7.00
  RODEO score: 0
  Monoisotopic mass: 521.2 Da
  Molecular weight: 521.6 Da
  Number of bridges: 1
allorf_2314479_2314571 - Class II
  Cleavage pHMM score: -7.00
  RODEO score: 0
  Monoisotopic mass: 2406.3 Da
  Molecular weight: 2407.8 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2425.8 Da N = 1

NZ_CP007597.1 - Region 4 - RRE-containing,RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,019,441 - 3,044,470 nt. (total: 25,030 nt) Show pHMM detection rules used
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0000554.1 |  |  | 0.32 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000558.1 |  |  | 0.31 | RiPP | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0001120.1 |  |  | 0.30 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001743.1 |  |  | 0.30 | RiPP | plantaricyclin | Lactobacillus plantarum
BGC0000294.1 |  |  | 0.30 | NRP | acinetobactin | Acinetobacter baumannii
BGC0001928.1 |  |  | 0.29 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0000768.1 |  |  | 0.29 | Saccharide | gellan polysaccharide | Sphingomonas elodea ATCC 31461
BGC0000797.1 |  |  | 0.29 | Saccharide | sphingan polysaccharide | Sphingomonas sp. S88
BGC0001540.1 |  |  | 0.29 | Other | CC-1065 | Streptomyces zelensis
BGC0001484.1 |  |  | 0.28 | Other | 2'-chloropentostatin, 2'-amino-2'-deoxyadenosine | Actinomadura sp. ATCC 39365

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000585.1 |  | 0.54 | RiPP | microcin C7 | Escherichia coli
BGC0000513.1 |  | 0.47 | RiPP | Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3 | Saccharopolyspora erythraea NRRL 2338
BGC0000554.1 |  | 0.47 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001391.1 |  | 0.47 | RiPP | thusin | Bacillus thuringiensis serovar rongseni
BGC0000500.1 |  | 0.47 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000552.1 |  | 0.47 | RiPP | SmbA, SmbB | Streptococcus mutans
BGC0000551.1 |  | 0.46 | RiPP | SapB | Streptomyces coelicolor A3(2)
BGC0000519.1 |  | 0.46 | RiPP | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis
BGC0000617.1 |  | 0.46 | RiPP | coagulin | Bacillus coagulans
BGC0001311.1 |  | 0.46 | RiPP | flavecins | Ruminococcus flavefaciens FD-1

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP007597.1 - Region 5 - LAP
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,723,033 - 3,745,131 nt. (total: 22,099 nt) Show pHMM detection rules used
LAP: ((((goadsporin_like or PF00881 or TIGR03605) and (YcaO or TIGR03882 or TIGR03604)) or TIGR03603 or TIGR03602) and not cyanobactin_synth)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | LAP | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001484.1 |  | 0.15 | Other | 2'-chloropentostatin, 2'-amino-2'-deoxyadenosine | Actinomadura sp. ATCC 39365
BGC0000843.1 |  | 0.11 | Other (Non-NRP beta-lactam) | alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate | Streptomyces clavuligerus ATCC 27064
BGC0001768.1 |  | 0.11 | NRP | sansalvamide | [Nectria] haematococca mpVI 77-13-4
BGC0000862.1 |  | 0.11 | Other | eicosapentaenoic acid | Shewanella pneumatophori
BGC0001302.1 |  | 0.10 | Other | lomofungin | Streptomyces lomondensis
BGC0000723.1 |  | 0.10 | Saccharide | β-D-galactosylvalidoxylamine-A | Streptomyces hygroscopicus subsp. limoneus
BGC0000610.1 |  | 0.10 | RiPP | nosiheptide | Streptomyces actuosus
BGC0001057.1 |  | 0.10 | NRP, Polyketide | zearalenone | Fusarium graminearum
BGC0001797.1 |  | 0.09 | RiPP | telomestatin | Streptomyces anulatus
BGC0000935.1 |  | 0.08 | Other (Aminocoumarin), Polyketide | esmeraldin | Streptomyces antibioticus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001484.1 |  | 0.45 | Other | 2'-chloropentostatin, 2'-amino-2'-deoxyadenosine | Actinomadura sp. ATCC 39365
BGC0000843.1 |  | 0.38 | Other (Non-NRP beta-lactam) | alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate | Streptomyces clavuligerus ATCC 27064
BGC0001768.1 |  | 0.38 | NRP | sansalvamide | [Nectria] haematococca mpVI 77-13-4
BGC0000862.1 |  | 0.37 | Other | eicosapentaenoic acid | Shewanella pneumatophori
BGC0001302.1 |  | 0.36 | Other | lomofungin | Streptomyces lomondensis
BGC0000723.1 |  | 0.36 | Saccharide | β-D-galactosylvalidoxylamine-A | Streptomyces hygroscopicus subsp. limoneus
BGC0000610.1 |  | 0.35 | RiPP | nosiheptide | Streptomyces actuosus
BGC0001057.1 |  | 0.35 | NRP, Polyketide | zearalenone | Fusarium graminearum
BGC0001797.1 |  | 0.34 | RiPP | telomestatin | Streptomyces anulatus
BGC0000935.1 |  | 0.32 | Other (Aminocoumarin), Polyketide | esmeraldin | Streptomyces antibioticus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
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Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
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Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
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