LOCUS       c00004_NZ_JYGE..       21374 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JYGE01000003.1 Peptostreptococcus russellii strain RT-10B
            contig_1_3, whole genome shotgun sequence.
ACCESSION   NZ_JYGE01000003
VERSION     NZ_JYGE01000003
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:14:36
            Original ID  :: NZ_JYGE01000003.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 198611
            Orig. end    :: 219985
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21374
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[208611:209985](+)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11374
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21374
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21374
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="2"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /tool="antismash"
     CDS             506..1546
                     /locus_tag="ctg4_168"
                     /transl_table=11
                     /translation="MKEKNRSRKRKRINKKKLLLVFIVLALLIFLIFKLAIGIKGIVKP
                     KEKESLPVKSEQDINQEEKKIINIMIDPAKGGSNAGMSNPNKTMSEKEINLDIAKKMQA
                     YILKHKDVRVMLTREYDDDKSLKSRADLAKENETDIFVSIRLNAQGSSDQAEGLDTYYI
                     APKAKVLKSSNKSQKKEDKGSESDKNDESSSKLEKTDKNKSEDERSDKESAEKESLDKE
                     SSDEVSSDKKSSEKESSNEDSSEKQTVIKRKNLSEGLAKSIQSTTLSFVEMKDRGVIQN
                     SFDILNYTEMPAVIVQCGFISNKKDAEKLSNEAFRQELADGISEGLLCFIDENRNEIIK
                     DRVNYR"
     PFAM_domain     710..1486
                     /aSDomain="Amidase_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01520.20"
                     /description="N-acetylmuramoyl-L-alanine amidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_168_0027"
                     /evalue="1.70E-39"
                     /label="ctg4_168"
                     /locus_tag="ctg4_168"
                     /protein_end="327"
                     /protein_start="68"
                     /score="135.7"
                     /tool="antismash"
                     /translation="IMIDPAKGGSNAGMSNPNKTMSEKEINLDIAKKMQAYILKHKDVR
                     VMLTREYDDDKSLKSRADLAKENETDIFVSIRLNAQGSSDQAEGLDTYYIAPKAKVLKS
                     SNKSQKKEDKGSESDKNDESSSKLEKTDKNKSEDERSDKESAEKESLDKESSDEVSSDK
                     KSSEKESSNEDSSEKQTVIKRKNLSEGLAKSIQSTTLSFVEMKDRGVIQNSFDILNYTE
                     MPAVIVQCGFISNKKDAEKLSNEAFRQELADGISEGL"
     CDS             1566..3278
                     /locus_tag="ctg4_169"
                     /transl_table=11
                     /translation="VDLYNTSRDYRERLSKEKCKANGIYYTPEPIVKLMVKEVLQEKEE
                     YKNLKILDIASGCGVFYSEILNYLIDDKSDIEEMLDIKSFISSNLYSIEKDKGSVEVLK
                     NYLQKRFGLEKDYKNNIITDDALFPKNKKIKEGMFDIIIGNPPYVGHKSIDVDYSKKLR
                     KYYPEVYVNKSDIYYCFFKIAIDYLKEGGVASLIVPRYFLESQSALLVRKFIEKNVEII
                     SIVDFRNSNVFLNGIGVSPCIITFKKNISRLLEKDNKEKEVVDNKKEVLLLNLPNIRII
                     KNKKDLDLLLSGKLIRANGYMDIDDTSWSLLTNSEKGIMDAIRKKQSYRLADIVDNYQG
                     VITGCDRAFIVEKDSELLEGMDKETIKRWIKSKDINPYFINDSDKVIVYTDDMKYSDIP
                     NIYKAQLKKYEERLKSRREVLRGIRAWYKLQWGRESMIFEQEKIIYPFKSKTNRFALDL
                     DKSFFSADVYFFTIKDEFKEKISYIYLLSILNSRIYQIYMQSFLKKMGNSIYEYYPYRL
                     LETYIFIDDSYKEIENLGKKILLEENESNIQILMNKIDIILEKSLNITDFIKK"
     PFAM_domain     1605..2417
                     /aSDomain="N6_Mtase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02384.18"
                     /description="N-6 DNA Methylase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_169_0028"
                     /evalue="7.90E-20"
                     /label="ctg4_169"
                     /locus_tag="ctg4_169"
                     /protein_end="284"
                     /protein_start="13"
                     /score="71.5"
                     /tool="antismash"
                     /translation="LSKEKCKANGIYYTPEPIVKLMVKEVLQEKEEYKNLKILDIASGC
                     GVFYSEILNYLIDDKSDIEEMLDIKSFISSNLYSIEKDKGSVEVLKNYLQKRFGLEKDY
                     KNNIITDDALFPKNKKIKEGMFDIIIGNPPYVGHKSIDVDYSKKLRKYYPEVYVNKSDI
                     YYCFFKIAIDYLKEGGVASLIVPRYFLESQSALLVRKFIEKNVEIISIVDFRNSNVFLN
                     GIGVSPCIITFKKNISRLLEKDNKEKEVVDNKKEVLLLNLPNIRIIKNK"
     PFAM_domain     2673..3116
                     /aSDomain="TaqI_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12950.9"
                     /description="TaqI-like C-terminal specificity domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_169_0029"
                     /evalue="1.60E-12"
                     /label="ctg4_169"
                     /locus_tag="ctg4_169"
                     /protein_end="517"
                     /protein_start="369"
                     /score="47.7"
                     /tool="antismash"
                     /translation="IKSKDINPYFINDSDKVIVYTDDMKYSDIPNIYKAQLKKYEERLK
                     SRREVLRGIRAWYKLQWGRESMIFEQEKIIYPFKSKTNRFALDLDKSFFSADVYFFTIK
                     DEFKEKISYIYLLSILNSRIYQIYMQSFLKKMGNSIYEYYPYRL"
     CDS             3430..3693
                     /locus_tag="ctg4_170"
                     /transl_table=11
                     /translation="MKKEVTIINETGLHARPASMFVKKASEFKSSVELIHEDEKVNAKS
                     IMGIMKLGLAKGTTVTIETNGEDEELALNSMVELIENGFGEK"
     aSDomain        3433..3672
                     /aSDomain="TIGR01003"
                     /aSTool="tigrfam"
                     /description="PTS_HPr_family: phosphocarrier, HPr family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_170_0010"
                     /evalue="2.30E-31"
                     /identifier="TIGR01003"
                     /label="ctg4_170"
                     /locus_tag="ctg4_170"
                     /protein_end="81"
                     /protein_start="1"
                     /score="105.6"
                     /tool="antismash"
                     /translation="KKEVTIINETGLHARPASMFVKKASEFKSSVELIHEDEKVNAKSI
                     MGIMKLGLAKGTTVTIETNGEDEELALNSMVELIE"
     PFAM_domain     3433..3672
                     /aSDomain="PTS-HPr"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00381.21"
                     /description="PTS HPr component phosphorylation site"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_170_0030"
                     /evalue="2.60E-32"
                     /label="ctg4_170"
                     /locus_tag="ctg4_170"
                     /protein_end="81"
                     /protein_start="1"
                     /score="111.0"
                     /tool="antismash"
                     /translation="KKEVTIINETGLHARPASMFVKKASEFKSSVELIHEDEKVNAKSI
                     MGIMKLGLAKGTTVTIETNGEDEELALNSMVELIE"
     CDS             3832..5547
                     /locus_tag="ctg4_171"
                     /transl_table=11
                     /translation="MMKGIGASPGIAIGKALVVEESEIVIEKKSISDIDSELKKLSDAV
                     LISKEELTKVKEKVAQEVGEEEAEIFGAHLLVLEDPEFIGEAENKIKNENINAEYALNE
                     VKDMFVSIFESMDNAYMKERAADVKDVTNRVLRHILGIKVVDLSSLSDEIVLVAHDLTP
                     SDTATMDKAKVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLSDVTKQVNDGDMIIFDGDV
                     GEVYINPDQKLIEEYEEKKRLFEEEKKALEELKGKESVTLDGKRVELAGNIGTPNDVEG
                     LIKNDAEGVGLYRTEFLYMNNDKFPEEETQYEAYKAVLEGMKGKPVVIRTLDIGGDKKL
                     SYFEMEEEMNPFLGYRAIRLCLDRTDIFKTQLRALYRSSVHGKLRIMFPMISSLEELLK
                     AKEICEEVKSELRDENIAYSDDVEVGMMIEIPSAAIISDVLAKHVDFFSIGTNDLIQYT
                     CAVDRMNQKISYLYNQFNPAVLRLINLVIKNAHAEGKWVGMCGESAGDQKMIPILLGFG
                     LDEFSMSPISILRARRLVTSVSQADMKKLSDEILGLTRAEEIEAYMDKFIENNK"
     PFAM_domain     3838..4203
                     /aSDomain="PEP-utilisers_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05524.15"
                     /description="PEP-utilising enzyme, N-terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_171_0031"
                     /evalue="1.80E-33"
                     /label="ctg4_171"
                     /locus_tag="ctg4_171"
                     /protein_end="124"
                     /protein_start="2"
                     /score="115.2"
                     /tool="antismash"
                     /translation="KGIGASPGIAIGKALVVEESEIVIEKKSISDIDSELKKLSDAVLI
                     SKEELTKVKEKVAQEVGEEEAEIFGAHLLVLEDPEFIGEAENKIKNENINAEYALNEVK
                     DMFVSIFESMDNAYMKER"
     aSDomain        3838..5523
                     /aSDomain="TIGR01417"
                     /aSTool="tigrfam"
                     /description="PTS_I_fam: phosphoenolpyruvate-protein
                     phosphotransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_171_0011"
                     /evalue="3.80E-226"
                     /identifier="TIGR01417"
                     /label="ctg4_171"
                     /locus_tag="ctg4_171"
                     /protein_end="564"
                     /protein_start="2"
                     /score="749.8"
                     /tool="antismash"
                     /translation="KGIGASPGIAIGKALVVEESEIVIEKKSISDIDSELKKLSDAVLI
                     SKEELTKVKEKVAQEVGEEEAEIFGAHLLVLEDPEFIGEAENKIKNENINAEYALNEVK
                     DMFVSIFESMDNAYMKERAADVKDVTNRVLRHILGIKVVDLSSLSDEIVLVAHDLTPSD
                     TATMDKAKVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLSDVTKQVNDGDMIIFDGDVGE
                     VYINPDQKLIEEYEEKKRLFEEEKKALEELKGKESVTLDGKRVELAGNIGTPNDVEGLI
                     KNDAEGVGLYRTEFLYMNNDKFPEEETQYEAYKAVLEGMKGKPVVIRTLDIGGDKKLSY
                     FEMEEEMNPFLGYRAIRLCLDRTDIFKTQLRALYRSSVHGKLRIMFPMISSLEELLKAK
                     EICEEVKSELRDENIAYSDDVEVGMMIEIPSAAIISDVLAKHVDFFSIGTNDLIQYTCA
                     VDRMNQKISYLYNQFNPAVLRLINLVIKNAHAEGKWVGMCGESAGDQKMIPILLGFGLD
                     EFSMSPISILRARRLVTSVSQADMKKLSDEILGLTRAEEIEAYMD"
     PFAM_domain     4285..4500
                     /aSDomain="PEP-utilizers"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00391.25"
                     /description="PEP-utilising enzyme, mobile domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_171_0032"
                     /evalue="6.50E-22"
                     /label="ctg4_171"
                     /locus_tag="ctg4_171"
                     /protein_end="223"
                     /protein_start="151"
                     /score="77.2"
                     /tool="antismash"
                     /translation="DEIVLVAHDLTPSDTATMDKAKVLGFLTDIGGRTSHTAIMSRTLE
                     IAAIVGLSDVTKQVNDGDMIIFDGDVG"
     PFAM_domain     4579..5445
                     /aSDomain="PEP-utilizers_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02896.20"
                     /description="PEP-utilising enzyme, PEP-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_171_0033"
                     /evalue="7.50E-122"
                     /label="ctg4_171"
                     /locus_tag="ctg4_171"
                     /protein_end="538"
                     /protein_start="249"
                     /score="406.1"
                     /tool="antismash"
                     /translation="ALEELKGKESVTLDGKRVELAGNIGTPNDVEGLIKNDAEGVGLYR
                     TEFLYMNNDKFPEEETQYEAYKAVLEGMKGKPVVIRTLDIGGDKKLSYFEMEEEMNPFL
                     GYRAIRLCLDRTDIFKTQLRALYRSSVHGKLRIMFPMISSLEELLKAKEICEEVKSELR
                     DENIAYSDDVEVGMMIEIPSAAIISDVLAKHVDFFSIGTNDLIQYTCAVDRMNQKISYL
                     YNQFNPAVLRLINLVIKNAHAEGKWVGMCGESAGDQKMIPILLGFGLDEFSMSPISILR
                     ARRLVTSV"
     CDS             6284..6937
                     /locus_tag="ctg4_172"
                     /transl_table=11
                     /translation="MLGDIVRYNFFALDDASEETYLLDYAIVLDGDDENDNIKILPFTS
                     SYHKDSIESFCIGCIPGFVEVKNEGYVNNRQYVHFNKILDVKRDELYPVHHQDVYGRIQ
                     KNNTGNPMNVRLAQEQLDKIVDRYGIYEEGEEKNLINLLIKSDAAFALNNEENNIAELR
                     EVSAKEMDKYREYNFTDKKVVVFFVDGKRYSVVMNATNNKDLDSRNNSLKKLLS"
     CDS             7531..8553
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 57.4; E-value: 3.8e-17)"
                     /gene_kind="other"
                     /locus_tag="ctg4_173"
                     /transl_table=11
                     /translation="MILADKLILLRKKNAWSQEELANKLDVSRQAVSKWEGAQSTPDLE
                     KIIKLSEIFNVSTDYLLKDNLEFDQDTLGTEDNTIGLQGESRTKEESLVRWISMEEASE
                     FLSIKKKNSKKVSYAVFLCIISSITLIVLSSISENNKYLLSENLASGIGLSVLFIFISI
                     AIAIFMSSSSKSARFDFLEKETFKTSDGVTSMVNKYKEDYREKYSRNNIIASIMCVLGA
                     LPIIIGSLIDGEDEVFISIMLSFTLIIVGVAVLIFVRNGIIWTSFEKLLEEGDYSKEKK
                     EEGKKFSNISTAYWLIATAIYLAYSFISYSWALSWIVWPVAGVLYPAMIAILKLFTNKK
                     "
     PFAM_domain     7558..7713
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_173_0034"
                     /evalue="3.80E-15"
                     /label="ctg4_173"
                     /locus_tag="ctg4_173"
                     /protein_end="61"
                     /protein_start="9"
                     /score="55.8"
                     /tool="antismash"
                     /translation="LRKKNAWSQEELANKLDVSRQAVSKWEGAQSTPDLEKIIKLSEIF
                     NVSTDYL"
     CDS             complement(8617..9684)
                     /locus_tag="ctg4_174"
                     /transl_table=11
                     /translation="LKLFKKSMVTLLALTMSATMVACGPKKKSNNTDKANQKIEYITEI
                     TKDNVEEVVIEYKEILSYYNDLKNNLKTINDVSKNPDLERDAVTAKDSIKNGVTLLKNT
                     QTLYKPLVEAKSVLVKMYGISLELADTVVTDPSKYQEKQKEYDKLFEEFKDMMDQIRSD
                     VEKVRGKSPTDDKNSEGKDTDGKKNSDINSLNDDSDKDSNDKDSSKNSSKNKNDDDDDK
                     SGSNSSNNSGNNNSSGNNNSGGSSSGGGSSSGGNSGGSGGGNSGGGNSGGSGGGDEFVP
                     PVSSLNNNIKSEIRSTGYREGVNYKQSGGSPSNVDQFASQLFNDLEGDNPIQGGQVAEA
                     RSIFVSAFKQGYNGN"
     CDS             10001..11374
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_175"
                     /sec_met_domain="PF04055 (E-value: 8.1e-15, bitscore: 50.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 8.8e-16, bitscore: 53.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.6e-21, bitscore:
                     71.8, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 6.6e-09, bitscore: 31.4,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 1.9e-27,
                     bitscore: 90.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKMIHKYNMNGYNIVVDVNGGAVHVVDDVTYRVLDFYEDKNLEEI
                     ISLLADEFDRQKIEESYNEIEELVKEGLLYTEDEYEFHPSFVNREPVVKALCLNVAHDC
                     NLKCKYCFAKQGDFGGNAELMSLDVGKKAMDFLVANSGNRRNLDIDFFGGEPLMNWEVV
                     KELVKYGREIEKPAGKNMRFTITTNGVLLDDEKIDFINEHMHNVVLSLDGRKEINDQMR
                     LTINDRGSYDTIVPKFQKLVSQRPKDKYYYVRGTFTRDNLDFSKDINHFADLGFELTSI
                     EPVVDDESNPFALREEDLPKIFEEYESYAAELAQRQLEGEKLKFFHFMIDLNQGPCVIK
                     RITGCGAGNEYVSIVPNGDIYPCHQFVGKEEFVMGNVHEDEITLPESMREMFREAHVYN
                     KESCKTCWNKFYCSGGCHANAINFNEDIRKPYELGCEMQKKRTECAIMIQAKLLTEGK"
     aSDomain        10010..11350
                     /aSDomain="TIGR03974"
                     /aSTool="tigrfam"
                     /description="rSAM_six_Cys: SCIFF radical SAM maturase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_175_0012"
                     /evalue="1.30E-219"
                     /identifier="TIGR03974"
                     /label="ctg4_175"
                     /locus_tag="ctg4_175"
                     /protein_end="450"
                     /protein_start="3"
                     /score="727.6"
                     /tool="antismash"
                     /translation="IHKYNMNGYNIVVDVNGGAVHVVDDVTYRVLDFYEDKNLEEIISL
                     LADEFDRQKIEESYNEIEELVKEGLLYTEDEYEFHPSFVNREPVVKALCLNVAHDCNLK
                     CKYCFAKQGDFGGNAELMSLDVGKKAMDFLVANSGNRRNLDIDFFGGEPLMNWEVVKEL
                     VKYGREIEKPAGKNMRFTITTNGVLLDDEKIDFINEHMHNVVLSLDGRKEINDQMRLTI
                     NDRGSYDTIVPKFQKLVSQRPKDKYYYVRGTFTRDNLDFSKDINHFADLGFELTSIEPV
                     VDDESNPFALREEDLPKIFEEYESYAAELAQRQLEGEKLKFFHFMIDLNQGPCVIKRIT
                     GCGAGNEYVSIVPNGDIYPCHQFVGKEEFVMGNVHEDEITLPESMREMFREAHVYNKES
                     CKTCWNKFYCSGGCHANAINFNEDIRKPYELGCEMQKKRTECAIMIQA"
     PFAM_domain     10298..10690
                     /aSDomain="Fer4_12"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13353.8"
                     /description="4Fe-4S single cluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_175_0035"
                     /evalue="1.50E-14"
                     /label="ctg4_175"
                     /locus_tag="ctg4_175"
                     /protein_end="230"
                     /protein_start="99"
                     /score="54.7"
                     /tool="antismash"
                     /translation="VAHDCNLKCKYCFAKQGDFGGNAELMSLDVGKKAMDFLVANSGNR
                     RNLDIDFFGGEPLMNWEVVKELVKYGREIEKPAGKNMRFTITTNGVLLDDEKIDFINEH
                     MHNVVLSLDGRKEINDQMRLTINDRGS"
     PFAM_domain     11033..11221
                     /aSDomain="SPASM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13186.8"
                     /description="Iron-sulfur cluster-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_175_0036"
                     /evalue="2.10E-07"
                     /label="ctg4_175"
                     /locus_tag="ctg4_175"
                     /protein_end="407"
                     /protein_start="344"
                     /score="31.4"
                     /tool="antismash"
                     /translation="CGAGNEYVSIVPNGDIYPCHQFVGKEEFVMGNVHEDEITLPESMR
                     EMFREAHVYNKESCKTCW"
     aSDomain        11033..11296
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_175_0013"
                     /evalue="1.20E-20"
                     /identifier="TIGR04085"
                     /label="ctg4_175"
                     /locus_tag="ctg4_175"
                     /protein_end="432"
                     /protein_start="344"
                     /score="71.8"
                     /tool="antismash"
                     /translation="CGAGNEYVSIVPNGDIYPCHQFVGKEEFVMGNVHEDEITLPESMR
                     EMFREAHVYNKESCKTCWNKFYCSGGCHANAINFNEDIRKPYE"
     CDS             11511..13187
                     /locus_tag="ctg4_176"
                     /transl_table=11
                     /translation="MRVSYKYLGRYKEIATVLIKYGFGFVVEKLNKDAVASKVNTHSPK
                     GEVKSMTTGQRMRYAFEELGPTYIKIGQILSTRKDIFDDEIISELSKLRDHVVAIDNDT
                     AMAILKEELGCELGDVFKRISKEPLAAASIGQVYEAQLLDGTVVVVKIQRPEIEETIKA
                     DLNILKRLADNLSFLNKDWNIDAQEMIAEMEIQLLRELDYKFEAINGIKLRKIFKDSKE
                     VFIPRIFDEYTTKKLLIMDKVEGICLSDIDEYQLSESDKKNIVDIGVRSFFRQVMTCGF
                     FHADPHPGNIFIVGNGNNKKISYIDFGMIGLIDEKTLKYLNQLIVASTNKNIYKIVRIL
                     TDMKAMPAESNSETLRRDLLYLIHYYYDIPFDKISIAEILNEGFRFMRTHNITLPSQLV
                     LLGKTVITLEGTSRGLYQDFSVETIAKSYMKYYRDEKLNLKRNISRLKSDLDEYYYDMV
                     TVPGQLKNILNILEKNKLKLEIGEVKAPKMEENITNFTTQVSMSIMLAACIVGSSLILS
                     SGNIKSNKMIKYIGIMGFILSFIIGIALVILILKSNYRKNK"
     PFAM_domain     11784..12524
                     /aSDomain="ABC1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03109.18"
                     /description="ABC1 atypical kinase-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_176_0037"
                     /evalue="1.70E-68"
                     /label="ctg4_176"
                     /locus_tag="ctg4_176"
                     /protein_end="338"
                     /protein_start="91"
                     /score="230.4"
                     /tool="antismash"
                     /translation="KLRDHVVAIDNDTAMAILKEELGCELGDVFKRISKEPLAAASIGQ
                     VYEAQLLDGTVVVVKIQRPEIEETIKADLNILKRLADNLSFLNKDWNIDAQEMIAEMEI
                     QLLRELDYKFEAINGIKLRKIFKDSKEVFIPRIFDEYTTKKLLIMDKVEGICLSDIDEY
                     QLSESDKKNIVDIGVRSFFRQVMTCGFFHADPHPGNIFIVGNGNNKKISYIDFGMIGLI
                     DEKTLKYLNQLIVASTNKNIYKIVR"
     CDS             13243..15759
                     /locus_tag="ctg4_177"
                     /transl_table=11
                     /translation="MKKWKLLNKTSASGNEVTRKLNIDDNIAQIMLNRNISEYEDIEMY
                     INPSFDFLRDPFLLMDMEKAVTRIKSAINNNEKICIYGDYDVDGVSSTSVLKIYFDSIG
                     YPVEYYIPNRLEEGYGLNKDAIDYIHSMKADLMITVDCGITSISEVDYANKLGIDVIIT
                     DHHECQGQIPNAYAVIDPKRDDCKYPFKGLCGCGVAFKLISALSGENKLKENINDYLEI
                     VSLATICDIMPVLDENRIIVKNGLEILASGNNVGMKALIKVCGLEGKKIKSSHLGFAIG
                     PRINACGRLGFSNLGVELFTEKNPDKAEKLAELMDLKNQERQDIEARIYKEAENLISSN
                     QVHQDGKVIVLAAENWHHGIIGIVASKLTEKYYKPCILLCIEGESATGSARSIKGFDLF
                     SALYECRDLMEKFGGHEQAAGLTISVDNIDELRNKINGIADYQLEVEDLIEEIKIEYEI
                     DAKDVTLDFVDKLHMLEPFGIKNPTPYFMMRDCYVKNVYLIGKDKSHLKMTISKDKDIE
                     CIGFSLSYLMEKFNIEDMVDIVFQVDENTYNGNTKVQLLIKDIRLNRPKDILKRPTYLK
                     EIDKLLNLDRAYLKEEDSLELEKSNIAKKEKKKKIEDNNEKIEVNKDIDIEYINNKISE
                     YLYRSNINISRIANIVDILSKDTLLVINSMNGFFRAISDINIASDEKIDYIFLSNIDKI
                     DLKVYNKIIMYDYFDNYQEIEYISKNKKDNSEILINFNSSDYIYIRNKFREIDFVRDNF
                     VLAYKFFMLNKKKTMGYSEFIEILGLSPIKVYTILKVLESEKLLKYKIDYDKDLFEFEL
                     LPKPDKKLDLEQNKIVKFLNSKIQID"
     aSDomain        13312..14922
                     /aSDomain="TIGR00644"
                     /aSTool="tigrfam"
                     /description="recJ: single-stranded-DNA-specific
                     exonuclease RecJ"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_177_0014"
                     /evalue="5.00E-186"
                     /identifier="TIGR00644"
                     /label="ctg4_177"
                     /locus_tag="ctg4_177"
                     /protein_end="560"
                     /protein_start="23"
                     /score="617.1"
                     /tool="antismash"
                     /translation="DDNIAQIMLNRNISEYEDIEMYINPSFDFLRDPFLLMDMEKAVTR
                     IKSAINNNEKICIYGDYDVDGVSSTSVLKIYFDSIGYPVEYYIPNRLEEGYGLNKDAID
                     YIHSMKADLMITVDCGITSISEVDYANKLGIDVIITDHHECQGQIPNAYAVIDPKRDDC
                     KYPFKGLCGCGVAFKLISALSGENKLKENINDYLEIVSLATICDIMPVLDENRIIVKNG
                     LEILASGNNVGMKALIKVCGLEGKKIKSSHLGFAIGPRINACGRLGFSNLGVELFTEKN
                     PDKAEKLAELMDLKNQERQDIEARIYKEAENLISSNQVHQDGKVIVLAAENWHHGIIGI
                     VASKLTEKYYKPCILLCIEGESATGSARSIKGFDLFSALYECRDLMEKFGGHEQAAGLT
                     ISVDNIDELRNKINGIADYQLEVEDLIEEIKIEYEIDAKDVTLDFVDKLHMLEPFGIKN
                     PTPYFMMRDCYVKNVYLIGKDKSHLKMTISKDKDIECIGFSLSYLMEKFNIEDMVDIVF
                     QVDENTYNGNTKVQLLIKDI"
     PFAM_domain     13474..13920
                     /aSDomain="DHH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01368.22"
                     /description="DHH family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_177_0038"
                     /evalue="1.50E-22"
                     /label="ctg4_177"
                     /locus_tag="ctg4_177"
                     /protein_end="226"
                     /protein_start="77"
                     /score="80.2"
                     /tool="antismash"
                     /translation="KICIYGDYDVDGVSSTSVLKIYFDSIGYPVEYYIPNRLEEGYGLN
                     KDAIDYIHSMKADLMITVDCGITSISEVDYANKLGIDVIITDHHECQGQIPNAYAVIDP
                     KRDDCKYPFKGLCGCGVAFKLISALSGENKLKENINDYLEIVSLA"
     PFAM_domain     14194..14550
                     /aSDomain="DHHA1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02272.21"
                     /description="DHHA1 domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_177_0039"
                     /evalue="2.50E-20"
                     /label="ctg4_177"
                     /locus_tag="ctg4_177"
                     /protein_end="436"
                     /protein_start="317"
                     /score="73.4"
                     /tool="antismash"
                     /translation="KNQERQDIEARIYKEAENLISSNQVHQDGKVIVLAAENWHHGIIG
                     IVASKLTEKYYKPCILLCIEGESATGSARSIKGFDLFSALYECRDLMEKFGGHEQAAGL
                     TISVDNIDELRNKIN"
     PFAM_domain     14602..14919
                     /aSDomain="RecJ_OB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17768.3"
                     /description="RecJ OB domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_177_0040"
                     /evalue="2.70E-29"
                     /label="ctg4_177"
                     /locus_tag="ctg4_177"
                     /protein_end="559"
                     /protein_start="453"
                     /score="101.7"
                     /tool="antismash"
                     /translation="IEYEIDAKDVTLDFVDKLHMLEPFGIKNPTPYFMMRDCYVKNVYL
                     IGKDKSHLKMTISKDKDIECIGFSLSYLMEKFNIEDMVDIVFQVDENTYNGNTKVQLLI
                     KD"
     CDS             15784..16305
                     /locus_tag="ctg4_178"
                     /transl_table=11
                     /translation="MNLEKKIRNIQDFPKPGIGFKDITTLLEDGEAFEYTIKKIAENIK
                     DLGVDVIVGPEARGFILGTPVAYELGIGFIPIRKPGKLPAEVESYEYSLEYGTDRLEIH
                     RDAIKPGDRVAIVDDLLATGGTIAAATKLVENLGGEVVAIEFLIELDFLNGRGKLDGYN
                     VNSLVHYSEE"
     aSDomain        15790..16293
                     /aSDomain="TIGR01090"
                     /aSTool="tigrfam"
                     /description="apt: adenine phosphoribosyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_178_0015"
                     /evalue="4.40E-70"
                     /identifier="TIGR01090"
                     /label="ctg4_178"
                     /locus_tag="ctg4_178"
                     /protein_end="170"
                     /protein_start="2"
                     /score="233.1"
                     /tool="antismash"
                     /translation="LEKKIRNIQDFPKPGIGFKDITTLLEDGEAFEYTIKKIAENIKDL
                     GVDVIVGPEARGFILGTPVAYELGIGFIPIRKPGKLPAEVESYEYSLEYGTDRLEIHRD
                     AIKPGDRVAIVDDLLATGGTIAAATKLVENLGGEVVAIEFLIELDFLNGRGKLDGYNVN
                     SLVHY"
     PFAM_domain     15862..16224
                     /aSDomain="Pribosyltran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00156.29"
                     /description="Phosphoribosyl transferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_178_0041"
                     /evalue="9.10E-14"
                     /label="ctg4_178"
                     /locus_tag="ctg4_178"
                     /protein_end="147"
                     /protein_start="26"
                     /score="51.2"
                     /tool="antismash"
                     /translation="LEDGEAFEYTIKKIAENIKDLGVDVIVGPEARGFILGTPVAYELG
                     IGFIPIRKPGKLPAEVESYEYSLEYGTDRLEIHRDAIKPGDRVAIVDDLLATGGTIAAA
                     TKLVENLGGEVVAIEFL"
     CDS             16364..18589
                     /locus_tag="ctg4_179"
                     /transl_table=11
                     /translation="MYDEDLKKLIEKIKTYSPNADFDKVARAYNLAKEAHEGQFRKSGE
                     PYFIHPKAVANILADMQLDEDTICGGLLHDVVEDTDYELDYIEEQFGKDVAILVDGVTK
                     LGKIKYMTKEESQSENLRKMFLAMAKDMRVILIKLADRLHNMRTLEYMNPEKAKYKAQE
                     TLDIYAGIAHRLGISKIKWELEDLSLRYLNGEGYYELVNMVKMKREQREKYIKDIVDLL
                     EKTFSDMDINCEVYGRPKHFYSIYKKMQKKHKSFDEIYDLTAVRVLVDSVKDCYAVLGV
                     VHTLWKPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPVEIQIRTHEMHNIAEYGIAAH
                     WKYKEGRADDEMSKADERLQWLRRMMEWEKDVTDPHEFLDALKDDVFSAQVYVFTPQGD
                     VIELPNEATPIDFAYRIHSKVGNACVGAKVNGRIVPLDYKLKNGEIVEVLTSSNSPGPS
                     RDWLGLVKTPNARNRIRQFFKKERREENIERGVEILDKEFKRNHINKNDVETINILKEV
                     GKKFNQPDYDDFLATIGYGGIAANHVLTKVKDVLLKEERKQEKEERATQEEDLERHNIG
                     ETDKAKNKSKRTEKRHTGVQVDGLEGIYVRFAKCCNPLPGDDIVGYITRGRGVTVHRVD
                     CENIIRDKKENQSRMVKVSWIDDNKSRFEAEIEVKAADRRGIVNEITHVISNEKIGLAG
                     IYARKGHELGITVNIILEVNGIEELQHIIKKIKNVPGVEDAFRVHGK"
     PFAM_domain     16445..16894
                     /aSDomain="HD_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13328.8"
                     /description="HD domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_179_0042"
                     /evalue="2.50E-49"
                     /label="ctg4_179"
                     /locus_tag="ctg4_179"
                     /protein_end="177"
                     /protein_start="27"
                     /score="167.1"
                     /tool="antismash"
                     /translation="AYNLAKEAHEGQFRKSGEPYFIHPKAVANILADMQLDEDTICGGL
                     LHDVVEDTDYELDYIEEQFGKDVAILVDGVTKLGKIKYMTKEESQSENLRKMFLAMAKD
                     MRVILIKLADRLHNMRTLEYMNPEKAKYKAQETLDIYAGIAHRLGI"
     aSDomain        16445..18562
                     /aSDomain="TIGR00691"
                     /aSTool="tigrfam"
                     /description="spoT_relA: RelA/SpoT family protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_179_0016"
                     /evalue="1.30E-251"
                     /identifier="TIGR00691"
                     /label="ctg4_179"
                     /locus_tag="ctg4_179"
                     /protein_end="733"
                     /protein_start="27"
                     /score="834.7"
                     /tool="antismash"
                     /translation="AYNLAKEAHEGQFRKSGEPYFIHPKAVANILADMQLDEDTICGGL
                     LHDVVEDTDYELDYIEEQFGKDVAILVDGVTKLGKIKYMTKEESQSENLRKMFLAMAKD
                     MRVILIKLADRLHNMRTLEYMNPEKAKYKAQETLDIYAGIAHRLGISKIKWELEDLSLR
                     YLNGEGYYELVNMVKMKREQREKYIKDIVDLLEKTFSDMDINCEVYGRPKHFYSIYKKM
                     QKKHKSFDEIYDLTAVRVLVDSVKDCYAVLGVVHTLWKPIPGRFKDYIAMPKPNMYQSL
                     HTTVVGPDGEPVEIQIRTHEMHNIAEYGIAAHWKYKEGRADDEMSKADERLQWLRRMME
                     WEKDVTDPHEFLDALKDDVFSAQVYVFTPQGDVIELPNEATPIDFAYRIHSKVGNACVG
                     AKVNGRIVPLDYKLKNGEIVEVLTSSNSPGPSRDWLGLVKTPNARNRIRQFFKKERREE
                     NIERGVEILDKEFKRNHINKNDVETINILKEVGKKFNQPDYDDFLATIGYGGIAANHVL
                     TKVKDVLLKEERKQEKEERATQEEDLERHNIGETDKAKNKSKRTEKRHTGVQVDGLEGI
                     YVRFAKCCNPLPGDDIVGYITRGRGVTVHRVDCENIIRDKKENQSRMVKVSWIDDNKSR
                     FEAEIEVKAADRRGIVNEITHVISNEKIGLAGIYARKGHELGITVNIILEVNGIEELQH
                     IIKKIKNVPGVE"
     PFAM_domain     17072..17401
                     /aSDomain="RelA_SpoT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04607.19"
                     /description="Region found in RelA / SpoT proteins"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_179_0043"
                     /evalue="3.30E-41"
                     /label="ctg4_179"
                     /locus_tag="ctg4_179"
                     /protein_end="346"
                     /protein_start="236"
                     /score="140.3"
                     /tool="antismash"
                     /translation="GRPKHFYSIYKKMQKKHKSFDEIYDLTAVRVLVDSVKDCYAVLGV
                     VHTLWKPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPVEIQIRTHEMHNIAEYGIAAH
                     WKYKEG"
     PFAM_domain     17534..17713
                     /aSDomain="TGS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02824.23"
                     /description="TGS domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_179_0044"
                     /evalue="1.30E-21"
                     /label="ctg4_179"
                     /locus_tag="ctg4_179"
                     /protein_end="450"
                     /protein_start="390"
                     /score="76.4"
                     /tool="antismash"
                     /translation="VYVFTPQGDVIELPNEATPIDFAYRIHSKVGNACVGAKVNGRIVP
                     LDYKLKNGEIVEVLT"
     PFAM_domain     17753..18280
                     /aSDomain="DUF5913"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF19296.1"
                     /description="Domain of unknown function (DUF5913)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_179_0045"
                     /evalue="7.00E-19"
                     /label="ctg4_179"
                     /locus_tag="ctg4_179"
                     /protein_end="639"
                     /protein_start="463"
                     /score="68.7"
                     /tool="antismash"
                     /translation="LVKTPNARNRIRQFFKKERREENIERGVEILDKEFKRNHINKNDV
                     ETINILKEVGKKFNQPDYDDFLATIGYGGIAANHVLTKVKDVLLKEERKQEKEERATQE
                     EDLERHNIGETDKAKNKSKRTEKRHTGVQVDGLEGIYVRFAKCCNPLPGDDIVGYITRG
                     RGVTVHRVDCENI"
     PFAM_domain     18344..18574
                     /aSDomain="ACT_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13291.8"
                     /description="ACT domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_179_0046"
                     /evalue="4.40E-17"
                     /label="ctg4_179"
                     /locus_tag="ctg4_179"
                     /protein_end="737"
                     /protein_start="660"
                     /score="62.5"
                     /tool="antismash"
                     /translation="SRFEAEIEVKAADRRGIVNEITHVISNEKIGLAGIYARKGHELGI
                     TVNIILEVNGIEELQHIIKKIKNVPGVEDAFR"
     aSDomain        18608..19042
                     /aSDomain="TIGR00256"
                     /aSTool="tigrfam"
                     /description="TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_180_0017"
                     /evalue="3.90E-57"
                     /identifier="TIGR00256"
                     /label="ctg4_180"
                     /locus_tag="ctg4_180"
                     /protein_end="145"
                     /protein_start="0"
                     /score="190.8"
                     /tool="antismash"
                     /translation="MRAVVQRVVSSNVKVDGETTGEIDKGLLVLLGVGEDDTPKDTAYM
                     VDKIVNLRIFEDEDEKMNLSLKDVGGELLVVSQFTLYGDCKKGRRPGFSDAARPDKADE
                     YYIDFVNKARELGVKTETGKFQTHMMVELINDGPVTLLVDS"
     CDS             18608..19057
                     /locus_tag="ctg4_180"
                     /transl_table=11
                     /translation="MRAVVQRVVSSNVKVDGETTGEIDKGLLVLLGVGEDDTPKDTAYM
                     VDKIVNLRIFEDEDEKMNLSLKDVGGELLVVSQFTLYGDCKKGRRPGFSDAARPDKADE
                     YYIDFVNKARELGVKTETGKFQTHMMVELINDGPVTLLVDSKKNF"
     PFAM_domain     18611..19039
                     /aSDomain="Tyr_Deacylase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02580.18"
                     /description="D-Tyr-tRNA(Tyr) deacylase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_180_0047"
                     /evalue="9.20E-56"
                     /label="ctg4_180"
                     /locus_tag="ctg4_180"
                     /protein_end="144"
                     /protein_start="1"
                     /score="188.4"
                     /tool="antismash"
                     /translation="RAVVQRVVSSNVKVDGETTGEIDKGLLVLLGVGEDDTPKDTAYMV
                     DKIVNLRIFEDEDEKMNLSLKDVGGELLVVSQFTLYGDCKKGRRPGFSDAARPDKADEY
                     YIDFVNKARELGVKTETGKFQTHMMVELINDGPVTLLVD"
     CDS             19067..19693
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170:metallo-beta-lactamase family protein (Score:
                     150.7; E-value: 5.9e-46)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_181"
                     /transl_table=11
                     /translation="MKIKVFVDSVMQENSYIYYDEKTLEAVIIDPALCLEKEKKFIDDN
                     KLNVKYIMLTHSHADHVADAEALKEYTGAAIIANKDEREMLIDAKKNLSSDFFTHGIEF
                     EADKYVSEGDKIQLGNNTFTFIDTPGHTTGGMCIRCNNDLFTGDTLFMGSIGRTDLYGG
                     NYDKMLKSLKKLSKLEDDLNIYPGHGPASTIGTEKASNYYMKLVI"
     PFAM_domain     19100..19630
                     /aSDomain="Lactamase_B"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00753.29"
                     /description="Metallo-beta-lactamase superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_181_0048"
                     /evalue="7.30E-25"
                     /label="ctg4_181"
                     /locus_tag="ctg4_181"
                     /protein_end="188"
                     /protein_start="11"
                     /score="88.2"
                     /tool="antismash"
                     /translation="QENSYIYYDEKTLEAVIIDPALCLEKEKKFIDDNKLNVKYIMLTH
                     SHADHVADAEALKEYTGAAIIANKDEREMLIDAKKNLSSDFFTHGIEFEADKYVSEGDK
                     IQLGNNTFTFIDTPGHTTGGMCIRCNNDLFTGDTLFMGSIGRTDLYGGNYDKMLKSLKK
                     LSKLEDDLNIYPGH"
     CDS             19693..21369
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_182"
                     /sec_met_domain="PF04055 (E-value: 1.5e-24, bitscore: 82.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKVLLQGHNYSYEIAEFLKLFSSEFSFLDGSEVFTVNQDMQDSE
                     VLVNKLEIIRKRDRVDIFTNTKVFLGGTELYNREIKESIDIETLDKSFVDIDKNSNDSE
                     NIKDNTEKYLVKKVIETEHNKKIFAKTNKKLDNNIKTISKRIIQRSMYYYLLDRFDANV
                     PWGILTGIRPVSIVNALFDMDMTEDDIRENMKREYLIKEEKLDLIIEIAKRERKYIYPL
                     SEDKISLYVSIPFCPTRCLYCSFPSHPLAKFGSLRHKYIETLLKEAKGVAELIKMQSKE
                     IETLYIGGGTPTALEADDLNYLITGLFNIFDLSKIKEFTVEAGRPDTITEEKLRTLKKH
                     NVSRISINPQTMNQETLETVGRNHSVEDIKDCFYMARKLDFDNINMDIILGLPGETPDM
                     VDSTMKEIIALDPESVTVHTLALKRASDLNINMNSYKDALASYQKMIEMIAISRKHMKD
                     NNYNPYYMYRQKHMLGNLENIGYSKEGYESLYNMQIMEDRQSNYAIGAGAVSKFVYLDE
                     TRIERVDDVKNLEIYLERVDDMIDKKYREVEKNANKSSKRN"
     aSDomain        20122..21327
                     /aSDomain="TIGR03994"
                     /aSTool="tigrfam"
                     /description="rSAM_HemZ: coproporphyrinogen dehydrogenase
                     HemZ"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_182_0018"
                     /evalue="2.20E-164"
                     /identifier="TIGR03994"
                     /label="ctg4_182"
                     /locus_tag="ctg4_182"
                     /protein_end="545"
                     /protein_start="143"
                     /score="545.3"
                     /tool="antismash"
                     /translation="KRIIQRSMYYYLLDRFDANVPWGILTGIRPVSIVNALFDMDMTED
                     DIRENMKREYLIKEEKLDLIIEIAKRERKYIYPLSEDKISLYVSIPFCPTRCLYCSFPS
                     HPLAKFGSLRHKYIETLLKEAKGVAELIKMQSKEIETLYIGGGTPTALEADDLNYLITG
                     LFNIFDLSKIKEFTVEAGRPDTITEEKLRTLKKHNVSRISINPQTMNQETLETVGRNHS
                     VEDIKDCFYMARKLDFDNINMDIILGLPGETPDMVDSTMKEIIALDPESVTVHTLALKR
                     ASDLNINMNSYKDALASYQKMIEMIAISRKHMKDNNYNPYYMYRQKHMLGNLENIGYSK
                     EGYESLYNMQIMEDRQSNYAIGAGAVSKFVYLDETRIERVDDVKNLEIYLERVDDMIDK
                     KYR"
     PFAM_domain     20383..20910
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_182_0049"
                     /evalue="6.30E-23"
                     /label="ctg4_182"
                     /locus_tag="ctg4_182"
                     /protein_end="406"
                     /protein_start="230"
                     /score="82.1"
                     /tool="antismash"
                     /translation="VSIPFCPTRCLYCSFPSHPLAKFGSLRHKYIETLLKEAKGVAELI
                     KMQSKEIETLYIGGGTPTALEADDLNYLITGLFNIFDLSKIKEFTVEAGRPDTITEEKL
                     RTLKKHNVSRISINPQTMNQETLETVGRNHSVEDIKDCFYMARKLDFDNINMDIILGLP
                     GETPDMVDSTMKE"
ORIGIN
        1 aaaagaaggt agtatattgc actagagagt gctcttatat agatggatta gacgatgagc
       61 aggctataaa aaatgcacaa caatatcttc caagtcataa gatagttgat agttttgatg
      121 aagtagattc acttccagtt aaggtatcat tttattcgga aaatggatat gatcatgact
      181 ttgaagctat tgttgaagag tttggagatt tagcaacagt ttgtacatcg ggatttgaat
      241 ggttggatgt tatccctaaa aatgcaagta agggaaatgg aattcaaaag atacaaaagt
      301 tgttaaatat agatgacagt gaaattatgg catttggaga tcagatgaat gattttgata
      361 tgctcagcaa ggtatattat agctatgcta tggataatgc aatcgatgaa ataaaacaaa
      421 tttcaagatt tagtgctcct tcaaacaatg agtatggcgt tattcaagtt ttaaaggaat
      481 tctttgagat agattaggag tagctatgaa agaaaaaaat agaagcagaa aaagaaagag
      541 gataaataag aaaaagcttt tactagtttt tattgtattg gctctcttga ttttccttat
      601 ttttaaattg gcaattggaa taaaaggaat agttaaacct aaggaaaaag aaagtctgcc
      661 tgtaaagtct gaacaggata taaatcaaga agagaagaag ataataaata ttatgataga
      721 tccagcaaag ggtggatcaa atgctggaat gtcaaatcca aataaaacta tgagtgaaaa
      781 agagataaat ttagatattg ccaaaaagat gcaagcttat attttaaaac acaaagatgt
      841 aagggtaatg cttacaagag aatatgatga tgataaaagt ttgaaaagta gagcagacct
      901 tgcaaaagaa aatgaaactg atatatttgt atctataagg ttaaatgctc aaggctcatc
      961 agatcaggca gaaggacttg atacatatta tattgctcca aaggctaaag tattgaagtc
     1021 atctaataag tctcaaaaaa aagaagacaa aggttcagag tcagataaaa atgatgaaag
     1081 tagttctaag ttggaaaaaa cagataaaaa taaatcagaa gatgagaggt cagataaaga
     1141 gtctgctgaa aaagaatctt tagataaaga aagctcagat gaagtatctt cagacaaaaa
     1201 atcctcagag aaagaaagtt caaatgagga ctcttcagag aaacaaactg ttataaaaag
     1261 aaaaaattta tcagaaggtc ttgcaaagtc tattcagtct acaactttat cttttgtaga
     1321 gatgaaagat agaggggtga tacaaaatag ttttgatatt ttaaattaca cagagatgcc
     1381 agcagttata gttcagtgtg gatttatatc aaataaaaaa gacgctgaaa agctctcaaa
     1441 tgaggctttt agacaggagt tagctgatgg cataagtgaa ggacttcttt gctttataga
     1501 tgaaaataga aatgaaataa ttaaagatag ggtaaattat agataatttt ggaaggagat
     1561 aattcgtgga tctttacaac acttcaaggg actatagaga acgattgagt aaagaaaagt
     1621 gtaaggcaaa tggtatatac tacactccag agccaattgt aaaactaatg gtaaaagaag
     1681 ttctacaaga aaaagaagag tataaaaatt taaagatatt ggatatagct tctggttgtg
     1741 gtgtttttta tagtgagatt ttaaactatt taattgatga taaaagtgat attgaagaga
     1801 tgcttgatat caaatctttt atatcgagca atttatattc aatagaaaaa gataagggat
     1861 ctgttgaagt gttgaagaat tatcttcaaa aaagattcgg cttggaaaaa gattataaga
     1921 ataatataat tactgatgat gctctatttc caaagaataa gaaaataaaa gaggggatgt
     1981 ttgatattat tatcggcaac cccccatatg ttgggcataa aagtatagat gttgattatt
     2041 ctaaaaagct gagaaaatat tatccggaag tctatgtcaa taagtcagat atatactatt
     2101 gtttttttaa gattgcaatt gattacttaa aagaaggtgg tgtggcatct ttaattgtcc
     2161 cgagatattt tctggagtca caatcagccc tactagtaag aaaattcata gaaaagaatg
     2221 ttgaaataat tagcattgtt gactttagaa atagtaatgt ttttttgaat ggaataggag
     2281 tatctccttg tatcattact tttaagaaaa atatttcgag attactagaa aaagataata
     2341 aagaaaagga agtagtggac aataaaaagg aagttttact attgaattta ccgaatattc
     2401 gtattataaa aaataaaaaa gatttagact tgcttttatc gggtaaacta ataagagcta
     2461 atgggtatat ggatattgat gatacttctt ggtctcttct taccaatagt gaaaagggga
     2521 taatggatgc aattagaaaa aagcaaagtt atagattggc tgatattgtc gacaactatc
     2581 aaggagtaat aactggttgt gatagagcct ttatagtgga aaaagactca gagcttttag
     2641 aggggatgga taaagaaacg ataaaaagat ggattaaatc caaggatatc aacccatact
     2701 ttattaatga ttcagataaa gtaattgtat atactgatga tatgaagtat tcggatatac
     2761 caaatattta caaagcacag cttaaaaaat atgaagaaag attaaaatct agaagagaag
     2821 tattaagagg gattagagcc tggtataaac ttcaatgggg cagagaatct atgatatttg
     2881 agcaagaaaa aataatatat ccatttaaat ctaaaacaaa tagatttgct ttggacttag
     2941 ataaatcttt ttttagtgca gatgtatatt tttttaccat aaaagatgag tttaaagaaa
     3001 aaatttctta tatttatctt ttatctattt taaattcaag aatatatcaa atatatatgc
     3061 agtctttttt gaaaaaaatg ggaaactcaa tatatgaata ttatccatat cgtttattgg
     3121 agacatatat atttatagat gattcttata aagaaataga aaatttgggc aaaaaaatac
     3181 ttttggaaga aaatgaaagt aatatacaga ttttgatgaa taaaatagat attattttag
     3241 aaaaaagttt aaatataaca gactttataa aaaaatagga aaaatgtgga aatttttctg
     3301 taaatgttat aaaatgaaat tataggtttt aatttgatat gcttttaaat aaatagggac
     3361 ataagttgac catgagggtc agcggtgctg aataaaagtt aataatgaat atatgatgga
     3421 ggttttatta tgaagaagga agtaacaata atcaatgaga caggtttaca tgctagacca
     3481 gcaagtatgt ttgtaaagaa ggcatcagaa tttaagtctt ctgttgaatt aattcatgaa
     3541 gacgaaaagg taaatgcaaa atcaataatg ggaataatga agcttggttt agccaaggga
     3601 acaactgtta ctatagaaac taatggtgaa gatgaagaat tagcactaaa ttctatggta
     3661 gaattaatag aaaacggctt tggcgaaaag taatataaat aagactgaat gttaagggct
     3721 gagcccttaa cattttttat aaattttaaa gttttataga gattaaattt tgaatgtaca
     3781 gaggcaagta atttttcttc tgtctgatac agaaaatttg gaggtagaat tatgatgaaa
     3841 ggtataggag catcaccagg aatagcaata ggaaaagctt tggtagtaga agagagtgaa
     3901 atagtaatag aaaaaaaatc gatatcagat atagattctg agcttaaaaa actttctgat
     3961 gctgtattga tatcaaaaga agagctaact aaagtaaagg aaaaagttgc tcaagaagtt
     4021 ggtgaggaag aggcagaaat atttggagct cacttactag ttcttgaaga ccctgaattt
     4081 attggcgaag cagaaaataa gataaaaaat gaaaatataa atgcggaata tgcattaaat
     4141 gaagttaaag atatgtttgt atctatattt gaatctatgg ataatgcata tatgaaggaa
     4201 agagcagcag atgtaaagga tgttactaat agagtgctaa gacatatatt aggaataaag
     4261 gtagtagatt tatcatcttt atctgatgaa atagtactag tagctcatga tttaactcca
     4321 tcggatactg caactatgga taaagcaaaa gttttaggat ttttaactga tattggaggc
     4381 agaacatcgc atacagctat tatgtcaaga acccttgaga tagcagctat agttgggcta
     4441 agtgatgtaa ctaagcaggt aaatgatggc gatatgataa tctttgatgg tgatgttgga
     4501 gaagtgtata ttaatccaga tcagaaactt attgaagaat atgaagaaaa gaaaagactg
     4561 tttgaagagg aaaagaaggc tcttgaagaa ttaaagggca aggaatccgt aacactagat
     4621 ggaaagcgcg ttgagttagc cggtaatata ggaactccta atgatgttga aggtcttatc
     4681 aaaaatgatg ctgaaggagt agggctatac agaacagaat ttttatatat gaataatgat
     4741 aaattcccag aggaagagac acagtacgaa gcttataagg ctgttcttga aggaatgaag
     4801 ggcaagcctg ttgtaataag aactcttgat ataggtgggg acaaaaaact aagttacttt
     4861 gaaatggaag aggagatgaa tccattttta ggttatagag caatcagact ttgccttgat
     4921 agaacagata tatttaaaac tcagttaaga gccctatata gatcttctgt tcatggaaaa
     4981 ttaagaataa tgtttcctat gatatcttca ctagaagagt tattaaaggc taaggaaatc
     5041 tgtgaagaag tgaaatctga gctaagagat gaaaatatag catattcaga tgatgttgaa
     5101 gttggtatga tgatagagat accttcagca gcgattatct ctgatgttct tgcaaaacac
     5161 gtagatttct tttcaatagg aacaaatgat ttaattcagt atacttgtgc agttgacaga
     5221 atgaaccaaa aaataagtta tttatataat cagtttaatc cagccgttct tagattgata
     5281 aatttagtaa ttaaaaatgc tcatgctgaa ggaaaatggg ttggcatgtg tggtgaatct
     5341 gcaggagacc aaaaaatgat accaatttta ctaggatttg gtttagatga attttctatg
     5401 tcaccaatat ctatcttaag agcaagaaga ttggtaacat cagtaagcca agctgatatg
     5461 aaaaaattat ctgatgagat tcttggactt acaagagcag aagaaataga agcctatatg
     5521 gataaattta tagaaaataa taaataagac tagtataaaa tattataaag tttaaattat
     5581 aaaagacagc atttgctgtc ttttttttat agaaatattt aaaagttata aaaaataagt
     5641 ataaaaagct tgtagacagc aataaatata aaaagattat gagaatataa ctataaaaat
     5701 agagataaat aaagtaaaac tataaacagt gctatcaaaa cagatatcta aaacaaatgt
     5761 atcaaaatag ggatctaaaa cagatattgt aaaattgaga ttaaaagata cacataaaaa
     5821 atagagatat atagatatct aaaagaaata taaaaataaa aaaagattat aaaaaatata
     5881 taaattatta attagaaata aaaaagagta tagcataata agccctagta gaataaaaac
     5941 aaaataatta aaataaaaaa tattgatttt tttcttttaa aaaataaact acttgtaagt
     6001 attggaattt caatatgcaa ttttttaact aaaattaatg gtcaaaaaaa gtccattagg
     6061 gacaaaaaat acactaatag aatatatatt agtcttttta tttattttag actatatatg
     6121 atatactata tatcaaaagt aggcatatat gatagtatat atagctttaa atttgattaa
     6181 aagtatagac aagtagaaaa aactatgcta atataaaatt ataaaagaaa tcaaacagat
     6241 ttaacattac aaataaaata tattaaatta cgggaggcac aacatgctag gagatattgt
     6301 aagatataat tttttcgcgt tggacgatgc tagtgaggag acttacttat tagattatgc
     6361 catagtttta gatggtgatg atgaaaacga taacatcaag atattgccat ttacgagcag
     6421 ttatcataag gactctatag aatctttttg cattggatgt attcctggtt ttgtagaagt
     6481 aaaaaatgag ggatatgtaa ataacagaca gtatgtacac tttaataaga tacttgatgt
     6541 aaagagagat gaattatatc cagttcatca ccaagatgta tatggacgta ttcaaaaaaa
     6601 taatactggt aatcctatga atgtaagatt agctcaagaa cagttagata aaatagtgga
     6661 tagatatgga atttatgagg aaggtgaaga aaaaaatctt atcaacttac ttataaaatc
     6721 tgatgcagcc tttgctttga ataatgaaga aaataatatt gctgagttaa gagaagtttc
     6781 tgctaaagaa atggataagt atagagaata taattttact gataaaaagg tagtagtttt
     6841 ctttgtagac ggtaaaaggt attcagtagt tatgaacgct acaaataata aagatttaga
     6901 tagtagaaat aatagtttaa aaaaactact aagttaatat aaaaataagc ttataagaaa
     6961 aaacaataat ttactaatac gttttgttta caaaactacc ataatcactc aaaaaatagt
     7021 cagttgccag ctggctattt tttatattca aaataatatt caatatacaa aaaataaaga
     7081 aaatatctag aaactatgac aattaattat tgtatgaaaa ataaaaaaga taatatttgt
     7141 atgaaatcaa attatataaa agagcaaatt gtagaaaaag agaaaattgc atgtaagagt
     7201 aagtcaggtt gagaataaaa gaatatcatt aaaaaagcag gaaaaagaaa gtaacaaaca
     7261 agtaaaaaaa taagtgatat atctaatata aaagtaaaat tgaaattttg agtgaggaaa
     7321 aataaataaa aacacaaatt ataagagtat aaaatataag aatttataaa taaatacaat
     7381 ttaaatgagt gtgaaagcct tggaataact aagtgcaacc aatagttgac aaattgacat
     7441 gtatgcttgc ttgctatcaa ctagataaat ttatataatt aatgcaagag ttaaaataaa
     7501 aaacacacta tattgagagg ggtattaaaa atgatactgg cagataaatt aattctactt
     7561 cgtaaaaaaa atgcttggtc acaagaggaa cttgccaaca aacttgatgt ttctagacag
     7621 gcagtttcaa aatgggaagg tgctcagtcc acacctgatt tagaaaaaat aataaaacta
     7681 tctgaaatat ttaatgtaag tacggactat ctactaaaag ataacttgga atttgatcaa
     7741 gacactttag ggacagaaga taatacaata ggattgcaag gtgagtctag aacaaaagaa
     7801 gaaagtttag taaggtggat atcaatggag gaagcttcgg agtttctgag cataaaaaag
     7861 aaaaattcaa aaaaagtttc atatgcagta tttttatgta tcatatcctc aataacacta
     7921 atcgtactta gctctattag tgaaaataat aagtatctac tttctgaaaa ccttgcaagc
     7981 gggataggac ttagcgtgtt atttatattt atatctatag caattgccat atttatgtct
     8041 agttctagca aaagtgcacg ctttgatttt ttagaaaaag aaacttttaa aactagcgat
     8101 ggagttacta gtatggtaaa taagtataag gaagattata gagagaaata ctctagaaat
     8161 aacattatag caagtattat gtgtgttcta ggtgccttac ccataattat tggatctttg
     8221 atagatggag aagatgaagt atttatttct ataatgcttt cttttacact aataattgtg
     8281 ggagttgctg ttttaatatt tgttaggaat ggaataattt ggacaagctt tgaaaagttg
     8341 ttagaagaag gggactattc gaaagaaaag aaagaagaag gaaagaaatt ttctaatata
     8401 agcacagctt actggcttat tgcgacagct atatatttgg cttatagctt tattagctat
     8461 agttgggctt tgagttggat tgtatggcca gtggcaggag tgctataccc agctatgata
     8521 gctatattaa aattatttac taataagaaa taaaaaaaca cctatctgat atcagatagg
     8581 tgttttaaat tcattgattt taaaagaaat tactaattaa tttccattgt atccttgttt
     8641 aaatgcactt acaaatattg atctagcttc tgcaacttga ccaccctgta ttggattatc
     8701 tccttcaagg tcattaaata gttgggacgc aaattgatca acattagaag ggctgcctcc
     8761 actttgcttg tagttaacac cctctctata tccagtgctt cttatttcac ttttaatatt
     8821 attatttaga cttgaaacag gtggtacaaa ttcatctcca ccgccagaac ctccagagtt
     8881 acctccgcca gagtttccac caccagaacc tccagagtta cctccgctag aacttcctcc
     8941 tccagaacta cttccgccag aattattatt tccactagaa ttgttatttc ctgagttatt
     9001 cgagctgtta gatccagatt tatcatcatc atcgtcgttt ttatttttgc tagaattctt
     9061 agaactgtct ttatcgtttg agtccttatc agaatcatca tttaaagagt tgatatcaga
     9121 atttttcttt ccatccgtat ccttaccttc agaattcttg tcatcagtag gtgactttcc
     9181 acgaaccttc tcaacgtcag aacgtatctg gtccatcata tccttaaact cttcgaataa
     9241 cttatcgtat tctttttgct tttcctgata tttactagga tctgttacca ctgtatctgc
     9301 tagttctaga gatataccat acatcttcac taaaacagat ttggcctcaa ctaaaggctt
     9361 atataaggtt tgagtattct ttagcagcgt aacaccattt ttgatagagt ctttagcagt
     9421 gactgcatct ctttcaaggt cagggttttt gctgacatca tttattgtct ttagattatt
     9481 tttcaaatca ttgtaataag aaagaatttc cttatactca attacaacct cttcaacatt
     9541 atcttttgtt atttcagtta tatattcaat tttttgatta gccttgtctg tattgttact
     9601 tttctttttt ggaccacacg caaccatagt tgcagacata gtcaaagcaa gcaacgttac
     9661 catcgatttt ttgaataatt tcaaaatatt cacctccatt tgtacatatg tatcattata
     9721 acatagaatt ttaatttaaa atataaaaaa tgtcaaattg aggatcttct aagatgtaag
     9781 aaatataagt tgaaatatat taaaaataag tagagcaaag gctttaacag tagatatact
     9841 tcatattaat aacaatatat aaaaaatagc aaaaatatat aaatatttat aagaaactgc
     9901 tttttaaatt atatgaattt cctattattt ttaaaaccct tgtatattta tgatataatg
     9961 ttatttgaat gatttataga aattaaagga ggaatatatt ttgaaaatga tacataagta
    10021 taatatgaac ggctacaaca tagtagtgga cgtaaatggc ggtgcagttc atgttgtaga
    10081 tgatgtgact tatagagttt tagactttta tgaagataaa aatttagaag aaataatatc
    10141 actattagca gatgaatttg acagacaaaa aatagaggaa tcatacaatg aaatagaaga
    10201 gttggttaaa gaaggtcttt tatatacaga agatgaatat gaatttcatc caagttttgt
    10261 aaatagagaa ccagtagtaa aggctctctg tttaaacgtt gctcatgatt gtaacttaaa
    10321 gtgcaagtac tgctttgcaa agcagggtga ctttggagga aatgctgagc tgatgtcttt
    10381 ggatgttggt aaaaaggcaa tggactttct agtagcaaac agtggaaata gaagaaatct
    10441 agatattgac tttttcggtg gggaaccact tatgaattgg gaagttgtaa aagagttggt
    10501 taaatatggt agagaaattg aaaaaccagc tggaaagaat atgagattta cgattactac
    10561 aaatggtgtt ttattagatg atgaaaaaat tgattttata aatgaacata tgcataatgt
    10621 agtactttct ctagatggta gaaaagaaat aaatgatcaa atgagattaa ctataaatga
    10681 tagaggtagc tatgatacta tagtaccgaa gttccaaaaa ttagttagcc aaagacctaa
    10741 ggataaatat tattatgtaa gaggaacatt tacaagagat aatcttgact tctcaaaaga
    10801 tattaatcat tttgcagact tgggatttga acttacatct atagagcctg ttgtggatga
    10861 cgagtcaaat ccatttgctc ttagagaaga ggatttacct aagatatttg aagagtatga
    10921 aagctatgca gctgaacttg cacaaagaca gttggaaggc gaaaagttaa agttcttcca
    10981 ctttatgatt gatttaaatc agggtccttg tgtaattaag agaattactg gttgtggagc
    11041 tggtaatgaa tatgtatcaa ttgttccaaa tggtgatata tatccatgcc atcagtttgt
    11101 aggtaaagaa gagtttgtta tgggaaatgt tcatgaagat gagataacac ttccagaatc
    11161 aatgagggaa atgtttagag aagctcatgt atataataaa gaaagttgta aaacttgttg
    11221 gaataagttc tattgttcag gtggctgtca tgcaaatgca attaacttca atgaagatat
    11281 tagaaagcca tatgaattag gttgcgaaat gcagaaaaag agaacagaat gtgcaataat
    11341 gatacaagca aaactattaa ctgaaggaaa ataatttaaa cataaatatg aaagactgca
    11401 atcttgtata attaaataga ttattatagg tgcagtcttt ttttatatca attaactttt
    11461 gagtagtagt tcttgcttta ataaatattt taaagggtga agattagaat atgagagtaa
    11521 gctataagta tttaggcagg tataaggaaa ttgctacggt tttgatcaag tatggatttg
    11581 gatttgtagt agaaaaacta aataaagacg cagttgcctc caaagtaaat acacattctc
    11641 caaaaggtga agtaaaatcg atgactacag gccagaggat gagatacgca tttgaagaat
    11701 taggtcctac ctatattaaa attggtcaga ttttaagtac aagaaaagat atttttgatg
    11761 atgaaataat atcagagtta tcaaaattga gggatcatgt agtagcaata gataatgata
    11821 cagcgatggc tatattaaaa gaagagcttg gctgtgaatt aggagatgta tttaaacgta
    11881 ttagcaaaga gccacttgca gcagcttcta taggccaggt atatgaagcc caactattgg
    11941 atggaacagt ggtagtagtt aaaatacaaa ggccagagat tgaagaaact ataaaggcag
    12001 acttgaatat attaaaaaga ttggctgaca atcttagttt tttaaataaa gattggaata
    12061 tagatgctca agagatgata gctgagatgg agattcaact actaagggaa ttggattata
    12121 aatttgaagc tataaatggc ataaaattaa gaaaaatatt taaagatagt aaggaagttt
    12181 ttattcctag aatatttgat gaatatacta caaaaaagtt attaataatg gataaggtag
    12241 aaggaatctg tttatctgat attgatgaat atcagcttag tgagtcagat aaaaaaaaca
    12301 ttgtagatat aggagtgagg tcatttttta ggcaggttat gacttgtggc ttttttcatg
    12361 cggatcctca cccaggtaat atatttattg ttgggaatgg caataataaa aaaatttcct
    12421 atatagattt tggtatgatt ggactgatag atgaaaagac tttaaaatat ttaaatcagt
    12481 taatagtagc ttcaacaaat aagaatatat ataaaattgt aaggatatta acagatatga
    12541 aagccatgcc agctgaatca aatagtgaga cactgagaag agatttgctt tatttgatac
    12601 actattatta tgatattcct tttgataaaa taagtattgc agaaatttta aatgaaggat
    12661 ttagatttat gagaactcat aatataacac ttccgtctca gttggttcta ttgggtaaga
    12721 cagttattac cttggaaggg acttctagag gtctatatca agattttagc gttgagacta
    12781 tagcaaagtc atatatgaaa tactacagag atgaaaagtt aaatctaaaa agaaatatat
    12841 caaggctaaa gtcagattta gatgaatatt attatgatat ggtgacagtt ccagggcaac
    12901 taaaaaacat cttaaatata ttagaaaaaa ataagttgaa acttgaaata ggcgaagtaa
    12961 aagctcctaa aatggaggaa aatattacta attttacaac acaagtatct atgagtataa
    13021 tgcttgctgc ttgtatagtt ggatcctcac ttatactatc atctggcaat ataaaatcaa
    13081 ataaaatgat taaatatata gggattatgg gatttattct atcctttata ataggtatag
    13141 cactagttat tttgatactt aaaagcaact acagaaaaaa taaataaggg gaaaaattaa
    13201 aaaagcttga actgggattt gaactgggaa gggaggtgct ttatgaagaa atggaaacta
    13261 ttaaataaga caagtgcaag tggaaatgaa gttacaagga agttaaatat agatgataat
    13321 attgcacaaa taatgctaaa tagaaatatc tcagaatatg aagacataga gatgtatata
    13381 aatccttcat ttgatttttt gagagaccct ttcttattaa tggatatgga aaaagcagtc
    13441 actagaataa aaagtgcaat taataataat gagaaaatat gtatatatgg ggactatgat
    13501 gttgatggag tatcttcgac atcagtttta aagatatatt ttgattctat tggatatcct
    13561 gttgaatact atattccaaa tagattagaa gaaggttatg gactaaataa agatgctata
    13621 gattatattc atagtatgaa agcagatctt atgataactg ttgactgtgg gattacatct
    13681 atatctgaag tagattatgc aaataaattg ggtatagatg taataataac agaccatcat
    13741 gagtgtcaag gtcaaatacc aaatgcctat gctgtaattg atcctaagag agatgattgt
    13801 aagtatccat ttaaggggct atgtggctgt ggagttgcat ttaagttaat aagtgccctt
    13861 agtggagaaa ataaacttaa ggaaaatata aatgattatc ttgagatagt atccttggct
    13921 acaatttgtg atattatgcc agtcttagat gaaaatagaa taattgttaa gaatggtctg
    13981 gaaatattgg caagtggaaa taatgttgga atgaaggcct tgataaaggt ttgtgggcta
    14041 gagggtaaga aaataaaaag ttctcatctt ggttttgcaa tagggcccag aataaatgct
    14101 tgtggaaggt taggtttttc aaatttagga gtagaattat ttacagagaa aaatccagac
    14161 aaagcagaaa aattagcaga attaatggat ttgaaaaatc aggaaagaca ggatatagaa
    14221 gctagaatat ataaagaggc agaaaacttg ataagttcaa atcaagtaca tcaagacgga
    14281 aaagttatcg ttttggcagc tgaaaactgg catcatggaa taataggtat agtagcttct
    14341 aaactaacag aaaaatacta taaaccatgt attcttcttt gcatagaagg tgaaagtgca
    14401 actggctcag ctagatctat taagggattt gatttattta gtgcccttta tgaatgcaga
    14461 gatttgatgg agaaatttgg aggtcatgag caggcagcgg ggttaaccat aagtgtagat
    14521 aatatagatg agcttagaaa taaaataaat ggcatagcgg actatcaact agaagtagaa
    14581 gatttgattg aagaaataaa gatagagtat gaaatagatg caaaagatgt tactttggat
    14641 tttgtagata aactacatat gctagagccg tttggaatca aaaatccaac tccatacttt
    14701 atgatgagag actgctatgt gaaaaatgta tacttgatag gaaaagataa aagccatctt
    14761 aaaatgacta tatctaaaga caaggacatt gaatgtattg gattctcttt aagctattta
    14821 atggagaagt ttaatataga ggatatggtt gatatagtat ttcaggtaga tgaaaatact
    14881 tacaatggaa atactaaagt tcagctatta ataaaagata ttaggttaaa tagaccaaaa
    14941 gatattttaa aaagaccaac ttacttaaaa gaaattgata aacttctaaa tcttgataga
    15001 gcttatttaa aagaagaaga ttctttagaa cttgagaaat ctaatatagc taaaaaagaa
    15061 aaaaagaaaa aaatagaaga taataacgaa aaaattgaag tcaataagga tattgatata
    15121 gaatatataa ataataaaat aagtgaatat ctgtatagat caaatataaa catatctagg
    15181 atagcaaata tagtcgatat actaagcaaa gatacattat tagttataaa tagtatgaat
    15241 ggatttttta gggctatttc cgatataaac atagcttcag atgaaaaaat cgactacata
    15301 tttttatcca atattgataa aattgattta aaagtatata ataaaattat tatgtatgat
    15361 tattttgata attatcaaga aatagaatat atttcgaaaa ataaaaaaga taattcggaa
    15421 attttaatta atttcaatag tagtgattat atatatataa ggaataaatt tagggagatt
    15481 gactttgtga gagacaattt tgtattagct tataagtttt ttatgttaaa taagaaaaaa
    15541 actatgggtt atagcgaatt tatcgagata ctaggacttt ctcctattaa agtttatact
    15601 atattaaaag tattagagag tgaaaaatta cttaaatata agatagacta tgataaagat
    15661 ttatttgaat ttgagttatt gccaaaacca gataaaaagt tggatttaga gcaaaataaa
    15721 attgttaagt ttctcaattc gaaaatacaa attgactaaa aagccaatat tatggaggaa
    15781 gaaatgaatt tagaaaaaaa gattagaaat atacaggatt ttccaaagcc tggtatagga
    15841 tttaaggata ttactacttt actagaagat ggagaagctt ttgaatacac tataaaaaaa
    15901 atagcagaga atataaagga tctaggggta gatgttatag ttggacctga agctagaggc
    15961 tttatattag gaactcctgt agcatatgaa ttagggatag gttttatacc tataagaaag
    16021 cctggaaaac ttcctgcaga agtagaatca tatgagtata gtttagaata tggaacagat
    16081 cgtcttgaga tacacagaga tgcaataaag ccaggtgata gggttgcaat tgtagatgat
    16141 ttattagcaa ctggcgggac aatagcagca gccactaagt tggtagaaaa cttaggtggt
    16201 gaagtagtag cgatagaatt tttaatagag ctagatttct taaatggtag aggcaaatta
    16261 gatgggtata atgtaaactc actagtacat tattcagaag aataattttg ggtcctgtta
    16321 ctttttgttt gaattagcga aatataataa gaggggtgac attatgtatg atgaagattt
    16381 aaaaaaatta atagaaaaga taaagacata ttcaccaaat gctgattttg ataaggtggc
    16441 aagggcttat aatttagcaa aagaagcaca tgaaggtcag tttagaaaat cgggtgaacc
    16501 gtactttata catccaaaag ctgttgccaa tatactggca gatatgcaat tagatgagga
    16561 tacaatttgt ggtggccttt tacatgatgt agttgaggat actgattatg agttggatta
    16621 tatagaagaa caatttggta aagacgttgc gatattggtt gatggagtca ctaagttagg
    16681 taaaatcaag tatatgacaa aagaagagtc acaatctgag aatttaagaa aaatgttttt
    16741 ggctatggct aaggatatga gagtaatact gataaaatta gctgatagac ttcataatat
    16801 gaggactctt gaatatatga atccagaaaa agctaaatat aaggctcaag aaacacttga
    16861 tatctatgcg gggattgctc acagattagg tatttctaag attaaatggg aattagaaga
    16921 tctttctttg aggtatctta atggcgaagg atattatgaa ttagtaaaca tggtaaaaat
    16981 gaagagagag caaagagaaa agtatataaa agatattgtg gatttgcttg aaaagacctt
    17041 cagtgatatg gatataaatt gtgaagtgta tggaagacca aaacattttt atagcatata
    17101 taaaaagatg caaaaaaaac ataaaagttt cgatgaaata tacgacttga cagcggttag
    17161 agtattggta gattcagtaa aagattgtta tgctgtgctg ggggtagttc atactttatg
    17221 gaagccgatt cctggtagat ttaaagacta tatagctatg ccaaagccaa atatgtatca
    17281 atcacttcat acaacagtag taggaccaga tggagaacct gtagagatac agattcgcac
    17341 tcatgaaatg cataacattg ctgagtatgg tatagcggct cactggaagt acaaagaagg
    17401 tagagctgat gatgaaatgt caaaggctga tgagagatta cagtggctaa gaagaatgat
    17461 ggaatgggaa aaagatgtta cagatcctca tgaattctta gatgccctaa aagatgatgt
    17521 ctttagtgca caagtttatg tatttacacc acagggagat gtaattgaac ttcctaatga
    17581 agcgacacca atagattttg cctatagaat tcactcaaaa gttggtaatg cttgtgttgg
    17641 tgcaaaagta aatggaagaa ttgttccact tgattataag ttaaaaaatg gagaaatagt
    17701 agaagtacta acttcatcaa actctccagg accaagtaga gactggctag gacttgtaaa
    17761 aacaccaaat gcaagaaata gaataagaca gttctttaaa aaagaaagaa gagaagaaaa
    17821 cattgaacgt ggagtagaga tactagataa agagttcaag agaaatcata taaataaaaa
    17881 tgatgtagaa acaataaata ttctaaaaga agtgggtaaa aaattcaatc agccagatta
    17941 cgatgacttt ttggccacta taggatatgg tggaatagct gcaaaccacg ttttgaccaa
    18001 ggtaaaagat gtattgctta aagaagaaag aaagcaagaa aaagaagaaa gagcaactca
    18061 agaagaggac cttgaaagac ataatattgg tgaaacagat aaggcaaaga acaagtctaa
    18121 gagaacagaa aaaagacaca caggagtaca ggttgatgga cttgaaggta tatatgttag
    18181 atttgccaag tgttgtaacc cacttccagg agatgatata gttggttata tcacaagagg
    18241 taggggagta actgttcata gagtagactg tgaaaatatc attcgcgata aaaaagaaaa
    18301 tcagagcaga atggtaaaag tttcgtggat agatgataat aaatctagat ttgaagctga
    18361 aatagaagta aaagctgcag atagaagagg aattgtaaat gaaattactc acgttatatc
    18421 taatgaaaag attggtcttg caggaatata tgcaagaaag ggtcatgaac ttggaataac
    18481 tgtaaatata atactagaag taaatggtat tgaggagttg cagcatataa taaagaaaat
    18541 aaaaaatgta ccaggtgttg aagatgcatt tagggtacat ggaaaataaa ttctaaagga
    18601 gtatcttatg agagcagtag ttcaaagagt agtatcatca aatgtaaagg tagatggtga
    18661 aactacaggt gaaattgaca aaggtttatt ggttttgcta ggagtaggtg aggatgatac
    18721 tcccaaagat accgcttata tggtagataa aatagttaac cttagaatat ttgaagacga
    18781 agatgaaaag atgaatttgt ctttaaaaga tgttggcggg gaacttttgg tagttagtca
    18841 gtttaccctt tatggtgatt gtaaaaaggg tagacgtcca ggttttagtg acgcagctag
    18901 acctgacaag gctgatgaat actatataga ttttgtaaat aaggcaagag agctaggagt
    18961 caaaacagaa actggaaaat tccaaacaca tatgatggtg gaattaatca atgatggacc
    19021 tgttacactt cttgttgact ctaagaaaaa tttttaggag gaaagaatga agataaaagt
    19081 atttgtagac tcggttatgc aggaaaattc atatatctac tatgatgaaa aaactttgga
    19141 agcggtaata atagatcctg cactttgctt ggaaaaagaa aagaagttta ttgatgataa
    19201 taaactaaac gttaaatata taatgcttac acactcacat gcggaccatg tagcagatgc
    19261 agaggcactg aaagaatata ctggtgcagc tataattgct aacaaggatg aaagagagat
    19321 gttaatagac gctaaaaaga atttgagtag cgactttttt acacatggca ttgagtttga
    19381 ggcggataag tatgtttctg aaggtgataa aattcagtta ggaaataata cttttacctt
    19441 tatagatact ccaggtcata caactggtgg aatgtgtata aggtgtaata atgacttatt
    19501 tacaggggat acacttttta tgggatctat aggtagaacg gacctatatg gtggtaacta
    19561 tgacaaaatg ttgaaatcac ttaaaaagct aagcaagcta gaagatgatt taaatatata
    19621 tccaggtcat gggccagcca gtactatagg gacagaaaaa gcaagtaact attatatgaa
    19681 attggtgatt taatgataaa agtactattg caaggacata attatagcta tgaaattgca
    19741 gagttcttga agttattttc ttctgagttt tcctttttgg atggctcaga agtttttact
    19801 gttaatcaag atatgcaaga ttcagaagta ttagtaaata agttagaaat tataaggaaa
    19861 agagatagag tagatatctt tacaaatact aaagtttttc taggtgggac tgagttatac
    19921 aatagagaaa taaaagaaag tattgatata gaaactcttg ataaaagctt tgtagatatt
    19981 gataaaaatt caaatgacag tgaaaatata aaagataata cagaaaaata tttagtaaaa
    20041 aaagtaatag aaacagaaca caataaaaaa atatttgcaa aaaccaacaa aaaattagat
    20101 aataatatta agacaatatc aaagcgaata attcaaagga gtatgtatta ctatctactg
    20161 gatagatttg atgcaaacgt tccgtggggg atacttactg ggattagacc cgtaagtatt
    20221 gtaaacgcgc tatttgatat ggatatgaca gaagacgaca tcagagaaaa tatgaaaaga
    20281 gagtatctta taaaagaaga aaagctagat ttaattatag aaatagctaa gagggaaaga
    20341 aaatatatct atcctctttc agaagataag atttctttat atgtaagtat acctttttgt
    20401 ccaacaagat gtctatactg ttcatttcca tcacatcctt tagctaaatt tggaagtcta
    20461 agacataaat atatagagac actattaaaa gaagcaaagg gtgtagctga actaataaag
    20521 atgcaatcaa aagagataga aactctttat ataggtggag gaactccaac agcattagaa
    20581 gcagatgatt tgaattattt aattacaggt ctatttaata tatttgattt atctaaaata
    20641 aaggaattta ctgtggaggc tggaagacca gatactatta ctgaggaaaa gctaagaact
    20701 cttaaaaagc acaatgtttc tagaataagt attaatccac aaactatgaa tcaagaaact
    20761 ctagagactg ttggaagaaa tcacagtgta gaagatatta aagattgctt ctatatggct
    20821 agaaaactag attttgataa tataaatatg gatataatac tgggacttcc tggtgaaact
    20881 ccagatatgg tagatagtac aatgaaagaa atcattgcac tagatccaga aagtgtaaca
    20941 gttcacactt tggctctaaa aagagcatct gatttaaata taaatatgaa tagttataag
    21001 gatgccttgg ctagttatca aaaaatgata gagatgatag caatttcaag aaaacatatg
    21061 aaagataata attataatcc atattatatg tataggcaaa aacatatgct tggaaaccta
    21121 gaaaatattg gttattcaaa agaaggatat gaatcccttt ataatatgca gattatggaa
    21181 gatagacaat ccaactatgc aataggtgct ggtgcagtat caaagtttgt ttatttggat
    21241 gaaacaagaa ttgaaagagt agatgacgtc aagaatctag agatatatct agagagagta
    21301 gacgatatga tagataaaaa atacagggag gtagaaaaaa atgctaacaa aagctccaag
    21361 aggaactaag gata
//
