LOCUS       NZ_CP051772.1          21879 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP051772.1 Mesorhizobium japonicum R7A chromosome, complete
            genome.
ACCESSION   NZ_CP051772
VERSION     NZ_CP051772.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 16:01:17
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3856049
            Orig. end    :: 3877928
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21879
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[3866049:3867928]"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03882) and TfuA)"
                     /neighbourhood="10000"
                     /product="thioamitides"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11879
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03882) and TfuA)"
                     /neighbourhood="10000"
                     /product="thioamitides"
                     /protocluster_number="1"
     cand_cluster    1..21879
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03882) and TfuA)"
                     /kind="single"
                     /product="thioamitides"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21879
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="thioamitides"
                     /region_number="4"
                     /rules="((YcaO or TIGR03882) and TfuA)"
                     /tool="antismash"
     CDS             1557..2993
                     /locus_tag="ctg1_3694"
                     /transl_table=11
                     /translation="VNIAGHITLLVHPQMVKVLASLIQMLADGLREISIETDIVHELPH
                     GFNGKAIVLGANLYGEIGLVYLPRNSVIFNVENYTSDWMSNEYTNILRRFSVWDFSESN
                     SLFLSEIISRPVHYFRTFYVSGLSRIIDENEDIDVLFYGSFNDRRSKILDEMRSRGLRV
                     EAAYGVFGEQLDRLIARSKVVLNLHFYDSGQLEIVRIFDLLANRRAVVSEVNSGELVDA
                     DLASAFVAATYENLVDVTEALVNDPDRRQKVAAAGFDAFSQRRAKKILPEALAWSDLPR
                     LPGDMVIGSGKMYDPNMLNIDIGTQWNPDIVADISDPDLLTREFITTRFGAVRLQPDLI
                     VSITASHVLEHIHDLVLAMKNCLELLAEGGLLKVAVPYDLSYGAWQDPTHVHAFNERSW
                     LYYCEWYWYLGWTEARFDLIEQTFHYSPLGHELAARGVSHDEILRAPRAVDEMHVVLRK
                     RQLTEAERAHGRQMRGDIRA"
     CDS             3545..4126
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156:Chloramphenicol acetyltransferase (Score: 70.9;
                     E-value: 1.8e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3695"
                     /transl_table=11
                     /translation="MPQVTPIFTRAALEGRGFDIGEYSYGVPTVRWWGEKASLKIGRFC
                     SIADGVEIFLGGNHRSDWITTYPFSAIAHWPEAENIPGHPATRGDVIIGNDVWIASHAM
                     IHSGVRIGDGAVIGAGSVVRRDVPPYALVAGNPAETVRLRFSEREVATLLKIRWWDWEE
                     ERIRETLPILLSGNISLFFDACGIPKELFS"
     PFAM_domain     3815..3913
                     /aSDomain="Hexapep_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14602.8"
                     /description="Hexapeptide repeat of succinyl-transferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3695_0083"
                     /evalue="2.50E-06"
                     /label="ctg1_3695"
                     /locus_tag="ctg1_3695"
                     /protein_end="123"
                     /protein_start="90"
                     /score="27.2"
                     /tool="antismash"
                     /translation="VIIGNDVWIASHAMIHSGVRIGDGAVIGAGSVV"
     CDS             4500..5312
                     /locus_tag="ctg1_3696"
                     /transl_table=11
                     /translation="MRPKTPSARPQPTLLTAPVELAGDWGRMLEGAADQVVERMRHACL
                     DGVRLVSDRQPTRLRVDEHTSGTPAIWLHPDGTSMAWIIVDIGERDWSKLAYQFGHELG
                     HVLCNSWQPDARPAPPCQWLEEAMVEAHSLRGLGRLARSWKEAPPFAGDNAFGDAIARY
                     RQDIIDRYTALADSQGLTRDAAAWFTDHRGEIEMPALNPFAQAMSLTILAEYDRAPDCI
                     EALGALNRWPGRSGLAIGEYLRQWEASCAELQASPRLPVRLRELLRIV"
     CDS             5512..5703
                     /locus_tag="ctg1_3697"
                     /transl_table=11
                     /translation="MERRHAIRRVSDGLWEVYDIDNNKVVRVGGVPLTNLLDEDALDAL
                     DLIRDGFLTLGQPKRTKA"
     CDS             6044..6217
                     /locus_tag="ctg1_3698"
                     /transl_table=11
                     /translation="MAPDGRPAFQVRRTSHIWIVDLLIIGHPFAPGDCVSEYSPIIFVS
                     HPDPIFLPFLGD"
     CDS             6834..10001
                     /gene_functions="regulatory (smcogs) SMCOG1149:LuxR family
                     transcriptional regulator (Score: 118.2; E-value: 5.9e-36)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_3699"
                     /transl_table=11
                     /translation="MSHESRVDVPNAGTGSRLPIGRGLMDDGVEARHERRVLTALCYDL
                     VGSTELLGLLGIEDFEELILAFQMAAKEAIVSCSGTVRVEVGDGGVAVFPVDLGAKDAA
                     SLTISAGLEIVRACKLLAAEKGRSDLHVRVGVATSMTLILKGDTGVAQDTVTGPAFALA
                     TRLQAIARPDTVVVCNETRNLTRRSHVFSFCGSHVIKGFAQPEQVWQALSHKRGVDRFF
                     AFGRLTSPLIDRTDEAKLIRECWNEAVSGRGQVIVIEGEAGIGKSRILHEVRRRTRFQR
                     NRLLLFQCMPGDSRSTLHPLRQAMLGNFDDGERALTPALVAEVFAAHGVHDPEVVDIFS
                     FLLGVEGVRSSFHEMDPEMIREKAEWAARHALQATCASGAVILIVEDIHWIDLTSKQLL
                     GELAKLVPSCPVLLIATTRPESGVWLDEKSKHVLLAPLEHADTLRAIATMWPQGKPAPA
                     PELKELVERVTGGVPLFIEEVCQWMAENAASGTEQLPQGVSLGRAAVLETVLDARLEPL
                     GRAREVARAAAVAGNRFSLDLLSALLPEFDPGTISAALDALVEAGFVRARHAAATVYAF
                     RHALIQETIYNATLRKRRQTLHRRLYAVASRNRSLVGWLTTAALADHAERAGLLDEAIG
                     EFVNAGMESSSRSAMAEARQLLEHAIALCGQVSDHDKRDALRLSAMVALGPILTAVEGP
                     NSEHARMLYDEGVKIARRRPIAERAKWFPIYWGWWFTGSVVDGERAQAVVSDLKEVNDP
                     EIQLQARHCLWAVDFNRGDHGGCIAAIDSGLPLYDVGQGHANATRFGGHDARVCGLAHR
                     ALSLWFSGRATSALRSMSEARRWAQRTGHVSSIAHACINDAMLSCYRRDFASLRNVIED
                     LRQLTALHHLPSLVVSAQIFEGWCDGNAGQLERGKDKMREGLGLHGQVQTPEDEPVYCG
                     MLAELLARSGAISHALALLHSAVAQAEAGGSRYWLAELHRRIAQLLVLDRAPAGRVAAA
                     LEQSLNTAAEQNAVPILIAAYETLSASNLSPGLLRSYNDRVEAARKSVEPGEPLIVNPE
                     PELRAGR"
     PFAM_domain     7524..8075
                     /aSDomain="AAA_16"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13191.8"
                     /description="AAA ATPase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3699_0084"
                     /evalue="2.40E-12"
                     /label="ctg1_3699"
                     /locus_tag="ctg1_3699"
                     /protein_end="414"
                     /protein_start="230"
                     /score="47.6"
                     /tool="antismash"
                     /translation="LIDRTDEAKLIRECWNEAVSGRGQVIVIEGEAGIGKSRILHEVRR
                     RTRFQRNRLLLFQCMPGDSRSTLHPLRQAMLGNFDDGERALTPALVAEVFAAHGVHDPE
                     VVDIFSFLLGVEGVRSSFHEMDPEMIREKAEWAARHALQATCASGAVILIVEDIHWIDL
                     TSKQLLGELAKLVPSCPVLLI"
     CDS             10001..11149
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: YcaO"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3700"
                     /sec_met_domain="YcaO (E-value: 1.6e-56, bitscore: 191.0,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VEHYERVGPPADEALTYLMSMRQALGITRIADITGLDRVGIPVVQ
                     ATRPFSLSNAVAQGKGASLARAAISAILESAEGFFAERIEYFDVIHGSAKSLEIPSGRY
                     ETWLREPTLADWRDKDTAWVSAENLLGGKCDFVPLELVHTAYLVPPSPCDGIFTPTTTG
                     LAAALDETDAITHGILECVERDAIARALQTHGFLQHQRIDPATIDDARVLALLGELARK
                     DMIVGLWLAPSPVGLPVIWCHLMESNPRETALLHLPADGSAAAFDPAAAAVQAIREAAQ
                     ARLAAISGARDDMTRASYPRYPDWQLIEAHRQLITGGRKDVSFARQRAYRAAGGQTLRG
                     SLLARLEESGINAVYLIRLNTSPWNRLSVVRMVIPQLYPLVE"
     aSDomain        10034..10900
                     /aSDomain="TIGR00702"
                     /aSTool="tigrfam"
                     /description="TIGR00702: YcaO-type kinase domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3700_0016"
                     /evalue="4.60E-34"
                     /identifier="TIGR00702"
                     /label="ctg1_3700"
                     /locus_tag="ctg1_3700"
                     /protein_end="300"
                     /protein_start="11"
                     /score="116.0"
                     /tool="antismash"
                     /translation="DEALTYLMSMRQALGITRIADITGLDRVGIPVVQATRPFSLSNAV
                     AQGKGASLARAAISAILESAEGFFAERIEYFDVIHGSAKSLEIPSGRYETWLREPTLAD
                     WRDKDTAWVSAENLLGGKCDFVPLELVHTAYLVPPSPCDGIFTPTTTGLAAALDETDAI
                     THGILECVERDAIARALQTHGFLQHQRIDPATIDDARVLALLGELARKDMIVGLWLAPS
                     PVGLPVIWCHLMESNPRETALLHLPADGSAAAFDPAAAAVQAIREAAQARLAAISGARD
                     DMTRASYP"
     PFAM_domain     10172..11131
                     /aSDomain="YcaO"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02624.18"
                     /description="YcaO cyclodehydratase, ATP-ad Mg2+-binding"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3700_0085"
                     /evalue="9.20E-47"
                     /label="ctg1_3700"
                     /locus_tag="ctg1_3700"
                     /protein_end="377"
                     /protein_start="57"
                     /score="160.0"
                     /tool="antismash"
                     /translation="QGKGASLARAAISAILESAEGFFAERIEYFDVIHGSAKSLEIPSG
                     RYETWLREPTLADWRDKDTAWVSAENLLGGKCDFVPLELVHTAYLVPPSPCDGIFTPTT
                     TGLAAALDETDAITHGILECVERDAIARALQTHGFLQHQRIDPATIDDARVLALLGELA
                     RKDMIVGLWLAPSPVGLPVIWCHLMESNPRETALLHLPADGSAAAFDPAAAAVQAIREA
                     AQARLAAISGARDDMTRASYPRYPDWQLIEAHRQLITGGRKDVSFARQRAYRAAGGQTL
                     RGSLLARLEESGINAVYLIRLNTSPWNRLSVVRMVIPQL"
     CDS             11154..11879
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: TfuA"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3701"
                     /sec_met_domain="TfuA (E-value: 5.3e-41, bitscore: 137.6,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPRLVFTGPTLSHPEAQQVADVICLAPAVQGSIVAAVQRYDPAA
                     IVIIDGAFQAEPAVRHKEILWAISQGIPVIGAGSMGALRAAELYPYMHGVGLIYRWYRR
                     FAVLPDDAVAVLYGPKAVNFSPLTHALVDLRMTVRVAWRRNLISTDLSGKLEGAARNLN
                     FRERTLSRMVREALPEAGDHDLQTCRQILAGAFVHQKKRDALSALQFMHENALVPAELK
                     NFRMTVGFAQDLEDAGLAV"
     PFAM_domain     11301..11657
                     /aSDomain="TfuA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07812.14"
                     /description="TfuA-like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3701_0086"
                     /evalue="6.70E-38"
                     /label="ctg1_3701"
                     /locus_tag="ctg1_3701"
                     /protein_end="168"
                     /protein_start="49"
                     /score="129.2"
                     /tool="antismash"
                     /translation="DGAFQAEPAVRHKEILWAISQGIPVIGAGSMGALRAAELYPYMHG
                     VGLIYRWYRRFAVLPDDAVAVLYGPKAVNFSPLTHALVDLRMTVRVAWRRNLISTDLSG
                     KLEGAARNLNFRERT"
     CDS             11965..13146
                     /locus_tag="ctg1_3702"
                     /transl_table=11
                     /translation="LNELDVAGRAGMSAGTRFLLYPQAPYVSGYEKPEVVWISTSPGLI
                     HPGPEDHRIYVRDPVLAKQPYEYPYLPPFVGAYFPPAEPGFDGHFDNLSLHSRPFLAAH
                     AFAAASRVLDIWESYLGKPIVWYFAETYERLEIIPWIDWENAQSGYGYLELGRERGADG
                     RGHPYALNFDVIAHEMGHSILFSLFGVPTKGLQDGDFGPFHEANADLISLLSFLHFDSG
                     MDRLLRHSQANLLVLNELNRIGELTGDRQIRLASNSRKMTEVTEEIHDRSRPFTGAIFD
                     TLVDLYHAGLVRQGLADERLLRFDIRQVSEADMRRISNFTGDAFRARPFLFKTELIKAR
                     DDVALSLARAWTRLDADHLTFAIAASTIIEVSDRFRPAVAASFEENFRWREIL"
     CDS             13176..13904
                     /locus_tag="ctg1_3703"
                     /transl_table=11
                     /translation="MSDDFHRPTLTFPGGAYNASQVRLYGIPGSGGLVFPGSSKAVGTK
                     NTSISSNMSTGDLKKDEKANAEINKILEGLRAAGENILSDEEIFKTLITTPPFPWPVGM
                     SYQIALDTRNFGKIALSTLLTIEEAARERKLLSCGIIVGYSYEGHCYDLPKPKIMLISA
                     FPQEIPADDCGYDKKNDQPSVADRYMLWIVDKLDECIEFETNQGFVEQIVLEANMPGKR
                     SPTMYASRMMMGHRGGRLGD"
     CDS             complement(14175..15509)
                     /locus_tag="ctg1_3704"
                     /transl_table=11
                     /translation="MATLHYASGGSATDVATAGFNLVDVSSVDELNALPAGTKGLVWLD
                     EANGATSSFIQKVTPFIGNPNVFGFFLVDEPDPTGKWGTYATADNLKAESDWIHTNLPG
                     AKTFITMMNMGSSADPDFSNTFNPANTHIDYYGVDPYPVRTGTSTVDYNMIDRTVAAAV
                     ASGVPLSQIVPVYQTFGGGNYTTDTGGQYVLPSVAQEQTMLDHWAKVAPSPAFDYAYAW
                     GSQQGDTALGNSPALQALFQQHNLSSAASGPATPPPSTSGASSTPSTPSTPSTPSTPST
                     PNTPDTHVSLGTASTPSTPVVANPSDGSHHHTNGADLIDRTDGVHHVPNANHWVTESAG
                     GHGRRGLASLADVGSDVFAFNTALTAGRADRATDFSQQKIHHDHALGLHTGAPPNGALF
                     AGMGTHDGGDHIIYNSSTGALSFDDHGTGGAHHIEFAHCPGASMI"
     PFAM_domain     16109..16984
                     /aSDomain="Dus"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01207.19"
                     /description="Dihydrouridine synthase (Dus)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3705_0087"
                     /evalue="1.20E-75"
                     /label="ctg1_3705"
                     /locus_tag="ctg1_3705"
                     /protein_end="292"
                     /protein_start="0"
                     /score="254.5"
                     /tool="antismash"
                     /translation="MMDWTDRHCRFFHRQLTSRALLYTEMVVADAVIHGARERLLGFDD
                     AEHPVALQLGGSDPAKLAEAARIGEAFGYDEVNLNVGCPSDRVQSGTFGACLMKVPDLV
                     AGCVTAMKAAVAIPVTVKCRIGVDEQDPEPALDALADGVFNAGADALWVHARKAWLEGL
                     SPKENRDIPPLDYNRVYRLKAKKPNEFIGINGGIQSLEEARAHLDHVDGAMLGRAAYHT
                     PGILAGVDAGFYGAKPEAFDFAALIDAMADYAARHIEQGGRLGHVTRHMVGLFHGLPGA
                     RRYRQILSTDA"
     aSDomain        16109..17038
                     /aSDomain="TIGR00742"
                     /aSTool="tigrfam"
                     /description="yjbN: tRNA dihydrouridine synthase A"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3705_0017"
                     /evalue="7.10E-124"
                     /identifier="TIGR00742"
                     /label="ctg1_3705"
                     /locus_tag="ctg1_3705"
                     /protein_end="310"
                     /protein_start="0"
                     /score="411.3"
                     /tool="antismash"
                     /translation="MMDWTDRHCRFFHRQLTSRALLYTEMVVADAVIHGARERLLGFDD
                     AEHPVALQLGGSDPAKLAEAARIGEAFGYDEVNLNVGCPSDRVQSGTFGACLMKVPDLV
                     AGCVTAMKAAVAIPVTVKCRIGVDEQDPEPALDALADGVFNAGADALWVHARKAWLEGL
                     SPKENRDIPPLDYNRVYRLKAKKPNEFIGINGGIQSLEEARAHLDHVDGAMLGRAAYHT
                     PGILAGVDAGFYGAKPEAFDFAALIDAMADYAARHIEQGGRLGHVTRHMVGLFHGLPGA
                     RRYRQILSTDANRPGAGPDVLKTAFAAVE"
     CDS             16109..17068
                     /locus_tag="ctg1_3705"
                     /transl_table=11
                     /translation="MMDWTDRHCRFFHRQLTSRALLYTEMVVADAVIHGARERLLGFDD
                     AEHPVALQLGGSDPAKLAEAARIGEAFGYDEVNLNVGCPSDRVQSGTFGACLMKVPDLV
                     AGCVTAMKAAVAIPVTVKCRIGVDEQDPEPALDALADGVFNAGADALWVHARKAWLEGL
                     SPKENRDIPPLDYNRVYRLKAKKPNEFIGINGGIQSLEEARAHLDHVDGAMLGRAAYHT
                     PGILAGVDAGFYGAKPEAFDFAALIDAMADYAARHIEQGGRLGHVTRHMVGLFHGLPGA
                     RRYRQILSTDANRPGAGPDVLKTAFAAVEFSGAAAEAA"
     CDS             complement(17071..17778)
                     /locus_tag="ctg1_3706"
                     /transl_table=11
                     /translation="MSSRLFWILMAVIGVGAALLVLNDSAGSTLGVENYDFGRLIWLGA
                     FGALIGAGLLRSGRPLGDMARNFGAWAAIVLALIAGYQYRYELQDIASRVTAGLVPGSP
                     LALGVEDGHATVTLDKADNGHFEARILVNSNPVRAVVDTGATSTVLTSEDAQAAGFNPA
                     ALNYTIPVSTANGMARAAAVKTDAVAIGGIVRKDMPVMVAAPGMLSQSLLGMNFIGSLS
                     GFDVRGDRMILRD"
     aSDomain        complement(17077..17433)
                     /aSDomain="TIGR02281"
                     /aSTool="tigrfam"
                     /description="clan_AA_DTGA: clan AA aspartic protease,
                     TIGR02281 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3706_0018"
                     /evalue="2.70E-43"
                     /identifier="TIGR02281"
                     /label="ctg1_3706"
                     /locus_tag="ctg1_3706"
                     /protein_end="234"
                     /protein_start="115"
                     /score="145.0"
                     /tool="antismash"
                     /translation="VTLDKADNGHFEARILVNSNPVRAVVDTGATSTVLTSEDAQAAGF
                     NPAALNYTIPVSTANGMARAAAVKTDAVAIGGIVRKDMPVMVAAPGMLSQSLLGMNFIG
                     SLSGFDVRGDRMILR"
     PFAM_domain     complement(17128..17391)
                     /aSDomain="Asp_protease_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13650.8"
                     /description="Aspartyl protease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3706_0088"
                     /evalue="9.80E-20"
                     /label="ctg1_3706"
                     /locus_tag="ctg1_3706"
                     /protein_end="217"
                     /protein_start="129"
                     /score="71.1"
                     /tool="antismash"
                     /translation="ILVNSNPVRAVVDTGATSTVLTSEDAQAAGFNPAALNYTIPVSTA
                     NGMARAAAVKTDAVAIGGIVRKDMPVMVAAPGMLSQSLLGMNF"
     CDS             complement(17890..18120)
                     /locus_tag="ctg1_3707"
                     /transl_table=11
                     /translation="MTAIESPCILVCSIDMKTGFCFGCGRTREEIGAWMGMTPETRRNV
                     MAELPARLETVERRPRRETRRTRMARERDAL"
     PFAM_domain     complement(17965..18105)
                     /aSDomain="DUF1289"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06945.15"
                     /description="Protein of unknown function (DUF1289)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3707_0089"
                     /evalue="9.50E-21"
                     /label="ctg1_3707"
                     /locus_tag="ctg1_3707"
                     /protein_end="52"
                     /protein_start="5"
                     /score="73.5"
                     /tool="antismash"
                     /translation="SPCILVCSIDMKTGFCFGCGRTREEIGAWMGMTPETRRNVMAELP
                     AR"
     CDS             18318..19316
                     /locus_tag="ctg1_3708"
                     /transl_table=11
                     /translation="MTSALPFDDFRNLLDNMPAADLKAEARVRALFAKADKPAHSLGRI
                     EDIAAWLAAWSGRAPPAVTRPLMAVFAGNHGVTRHGISPRPVAATANAVELCAAGGAAI
                     NQICIAYDLGLKVFDLALHIPTGDIAEDAALDERGCAATMAFGMEAIAGGTDLLCLGDL
                     GVGNSTVAAALFAALFGGRRADWVGPGSGADAAMQARKADVVDAALAFHHGHLDDPLEV
                     LRRVGGREFAAIAGAILAARMQKIPVLLDGFATTAAAAVLYAANPGALDHCLLASLSPE
                     PAHTRAAELLGFRPLLDLGIGHGEGAGAALGAGLVKAAALTSSGMAAAVRI"
     PFAM_domain     18369..19298
                     /aSDomain="DBI_PRT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02277.19"
                     /description="Phosphoribosyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3708_0090"
                     /evalue="5.20E-86"
                     /label="ctg1_3708"
                     /locus_tag="ctg1_3708"
                     /protein_end="327"
                     /protein_start="17"
                     /score="289.0"
                     /tool="antismash"
                     /translation="PAADLKAEARVRALFAKADKPAHSLGRIEDIAAWLAAWSGRAPPA
                     VTRPLMAVFAGNHGVTRHGISPRPVAATANAVELCAAGGAAINQICIAYDLGLKVFDLA
                     LHIPTGDIAEDAALDERGCAATMAFGMEAIAGGTDLLCLGDLGVGNSTVAAALFAALFG
                     GRRADWVGPGSGADAAMQARKADVVDAALAFHHGHLDDPLEVLRRVGGREFAAIAGAIL
                     AARMQKIPVLLDGFATTAAAAVLYAANPGALDHCLLASLSPEPAHTRAAELLGFRPLLD
                     LGIGHGEGAGAALGAGLVKAAALTSSGMA"
     CDS             complement(19349..20869)
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 245.9; E-value: 1.9e-74)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_3709"
                     /transl_table=11
                     /translation="MPLQRSNTADKFIVDRRKPHRNSDVARAVRKTRDRLSQQAGNPDF
                     DRELLKLHAGAMTSGAVVIPLLVLAIAAAGWLAGVGNEIGLWALFTLTCYTIVAFMARR
                     IERTEASELNPLQTRREFLVGHFLCGLGWGWFVVLGCGACAVDQFPVVKAVVLLLAMAG
                     TALMASSLSGALLATFAVPVALYAYVGTRLWMPVEAMMAGLLVLSLPFFVYVARQLNRA
                     SLMLLSFRSEKDALIAELETAKSMSDEARRRAEDANLAKSRFLASMSHELRTPLNAILG
                     FSEVMANEVLGPMSNPTYRDYAHDVHDSGQHLLDLINEILDLSRIEAGRYQLNEEPVML
                     LNIVEDCCHMMELKARNKDIRVVQDFEQTLPRLFADERAVRQITLNLLSNAIKFTATGG
                     EIRVRVGWTAGGGQYISVKDNGPGIPEDEIPVVLSAFGQGSIAIKSAEQGTGLGLPIVQ
                     GLLAMHGGEFELHSKLREGTEAIAIFPLSRVMEELPALPTAAVAARRR"
     PFAM_domain     complement(19412..19744)
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3709_0092"
                     /evalue="1.90E-22"
                     /label="ctg1_3709"
                     /locus_tag="ctg1_3709"
                     /protein_end="486"
                     /protein_start="375"
                     /score="80.0"
                     /tool="antismash"
                     /translation="DERAVRQITLNLLSNAIKFTATGGEIRVRVGWTAGGGQYISVKDN
                     GPGIPEDEIPVVLSAFGQGSIAIKSAEQGTGLGLPIVQGLLAMHGGEFELHSKLREGTE
                     AIAIFPL"
     PFAM_domain     complement(19883..20092)
                     /aSDomain="HisKA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00512.27"
                     /description="His Kinase A (phospho-acceptor) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3709_0091"
                     /evalue="1.20E-19"
                     /label="ctg1_3709"
                     /locus_tag="ctg1_3709"
                     /protein_end="329"
                     /protein_start="259"
                     /score="70.1"
                     /tool="antismash"
                     /translation="AKSRFLASMSHELRTPLNAILGFSEVMANEVLGPMSNPTYRDYAH
                     DVHDSGQHLLDLINEILDLSRIEAG"
     CDS             20946..21569
                     /locus_tag="ctg1_3710"
                     /transl_table=11
                     /translation="MSRSWSPRSRRRYAAPRPRSLWRKVLDYGLTIIILGLLILLAARL
                     DRVETRQTQGAAIINDGDSITLGTERIRMRGIDAPEYTQTCRRNGVDYACGTLARQSLV
                     RLIAGRPVTCSGWQRDRYGRLLGDCKAGGTDLNRAQVEAGWAVAFGDFESEEATARAAK
                     VGIWAGTFDQPQDWRDSHHGEVVERKHGTLASIGDAVREIFRFW"
     PFAM_domain     21156..21449
                     /aSDomain="SNase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00565.19"
                     /description="Staphylococcal nuclease homologue"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3710_0093"
                     /evalue="8.70E-10"
                     /label="ctg1_3710"
                     /locus_tag="ctg1_3710"
                     /protein_end="168"
                     /protein_start="70"
                     /score="39.1"
                     /tool="antismash"
                     /translation="RIRMRGIDAPEYTQTCRRNGVDYACGTLARQSLVRLIAGRPVTCS
                     GWQRDRYGRLLGDCKAGGTDLNRAQVEAGWAVAFGDFESEEATARAAKVGIWA"
ORIGIN
        1 cacgaatgga acgagacgcg cttcagggtg cttggccgaa tccgcaacat aagtttgcgg
       61 aaaactctcg aacacagctg cgacttctat ttcgttgccg acgtcgataa tttcgtgcga
      121 ccggccacgc tacgcgagct tgtcgcgctc gacgtgccga tcgtcgctcc cctgcttcgc
      181 tccatctctc ccgggcaata ctattcgaac taccacgccg aaatcgacgc caacggctac
      241 tatatgcagt gcgatcaata tgggtgggtg ctcaaccgcc acgtgcgcgg cattatcgag
      301 atgccgcttg tgcactgcac gtatcttgtc cgcgccgacg tactgaccga actgacatac
      361 gaggacgcca catcacgcta cgagtatgtg atctttgccg acagcgcccg caaggccggc
      421 atcgtccagt atatggataa ccgacaagtc tatggctaca tcaccttcgg cgatggccaa
      481 tattatgtga gtgacgggat cgagcgcgcc cgagcgctgt tgcacggtgc gggggacacg
      541 ccggtattca ctgccgccac gcctccgggc gccgtaccga tgccagatcg acatgtcgag
      601 ccgaaggatc cgccgaaaat acacctgata aacctcgacc gcagcgtcga gcgctggagc
      661 aggtatcaaa gcaataactg gcacctaacg cacgatacgg ttcgtgtgtc ggccgttgac
      721 ggcacttctc tcgacaggga ggcgctcata aaggaaggtc tgatcaccaa tgattgtgcg
      781 taccccccgg gcactttggg atgcgctcta tcccatatcg gcttatggaa gttggcggtt
      841 tcagagaaca agacgataac tatttttgaa gacgacgttc gagcatcgtt tcgatttgtg
      901 gaggaatccg ccaatatact atctcaagca ccggaaagct gggatttgat acagtgggga
      961 tatatatacg acccgttgtt tctctgggta aatctcggct tctccaaagc caagttggaa
     1021 ttttacgatc gtcagtataa gaatacaccc accttgtttc aggccgacaa attttctcga
     1081 tccctcatca aggtggagca ctcatttggg attcaggcct acacagtcac gccacgaggc
     1141 gcgcgaatac ttctggaaaa gtgtttgccg ctacgaagca ggcagattcc ctttcctgga
     1201 actgctgtca tcctcgatga cacgggtatc gattgcgcga tgtgtgcggc atatggctct
     1261 atgcaagctt tcgtttgcat gccaccactc gtcattcacg ataacgaact gccgtcagac
     1321 cggatagacg cagatcaccg agagccgggc tagtttgtca tggaatcaca acagactcct
     1381 attagcgcgg cgcgcgcatg tgcgagggaa gacgaagata ctgcctatgg ggtggtgggg
     1441 gctagactct gtcgcgcgcc aaatgtcgac gcgacgggta atattcgatc ggagggtctg
     1501 cccgcctcgg cgcagaaatt gtggcaggta agatacgaac tcctcgggag aacggcgtga
     1561 acattgcggg tcacatcaca cttctcgttc acccacagat ggtgaaggtg ctcgcaagct
     1621 tgattcagat gctcgccgat gggctgcgcg agatttccat cgaaactgat attgtccacg
     1681 aattgccgca tgggttcaac gggaaggcaa tcgtattagg tgctaacctg tatggggaga
     1741 ttgggttagt ctatctgcca agaaattctg ttatatttaa cgttgaaaat tacacgtctg
     1801 actggatgtc gaacgaatac acaaatatac ttcgtcgatt ttctgtttgg gattttagtg
     1861 agagcaattc actattttta tccgaaatca tttcccgacc agtacactac tttagaacat
     1921 tctatgtttc cggcctttca aggataattg atgaaaatga agatatagat gtcctattct
     1981 atggttcctt taatgacagg aggtccaaaa ttcttgacga aatgcgctct cgcgggctgc
     2041 gcgttgaggc ggcgtatggc gtattcggcg aacagcttga ccgccttatc gcacgatcga
     2101 aagtggtact caatttgcat ttctacgaca gtgggcagct tgaaatcgtt cgcatttttg
     2161 atctgttggc gaacaggcgc gctgtggtaa gcgaggtaaa ctcgggcgaa ctggtggatg
     2221 ccgatttggc cagcgccttt gttgcagcca cttacgagaa cctcgtcgat gtaaccgagg
     2281 cgctagttaa cgacccagat cgacgtcaaa aagtagcagc agcaggcttc gacgcattta
     2341 gtcaacgccg cgccaaaaaa atacttcctg aagcactagc ctggagtgat ttgccacgcc
     2401 ttccgggcga tatggtgatt ggcagcggca agatgtatga tccgaatatg ctcaatatcg
     2461 acattggcac ccaatggaat cctgatattg tcgccgatat atcagatccg gatctattga
     2521 cccgtgagtt tataacaacg cgctttggcg ctgtccgcct ccagcccgat ctgattgtga
     2581 gtataaccgc ctcacatgta ctagagcaca ttcatgacct cgttttagcc atgaaaaatt
     2641 gcttggaatt attggcggaa ggcggccttc ttaaggtagc tgttccatat gatttatcat
     2701 atggtgcttg gcaagatccc actcatgtgc acgcttttaa tgaaagaagt tggctctact
     2761 attgcgaatg gtactggtat ctcggctgga ccgaagctag attcgatttg attgaacaga
     2821 cgtttcacta cagtcccttg ggccacgagc ttgcggcacg gggcgtttca catgacgaga
     2881 ttttgcgtgc accgcgggcg gtagacgaga tgcatgtggt gctacgcaag aggcaactaa
     2941 ctgaggctga gcgtgcccat gggcgccaaa tgcggggcga catacgcgcg tgaaattcga
     3001 tgcaaagctg cctgctcctc gaatttgcct cgccgtcatg accctttctt agggaccgga
     3061 ttcagcgtcg cagatggcga tcccaaagat ccgtttctca tcgcgaggcg ctaccaatag
     3121 ctccgccagc gcccacttcg gcgaccttgc tttgtccgac aggcagctat gatttgtcgc
     3181 cgtgaaaagc tcggccagct cagtaactcc gtgaactgcg tacgcgttcc cccagcagtt
     3241 gcgccgcagt cttcccaacc tcgacggtcg ccatggtcgt tgcagaggcg gcgtttccaa
     3301 tcaccatgcc ccagtcgcat gcggtgtccg aagtacggct cacgccgggt gaccgtccgg
     3361 ccgtcgcttc tgggtagtat tcggctgccg tggcacgcca catgccctag gctggcggcg
     3421 gacaaattat attcggtgtc gtaccatcgg tgtcctcgat tgcagcaacc tgatattgaa
     3481 gtggggcaac gagtcttgtg aagaaggcta tctccgcgtc aaggtccagg agtcgaaata
     3541 atagatgcct caggtcactc caatcttcac tcgagctgcg ttggagggca gaggttttga
     3601 cattggagaa tatagctatg gagttcccac cgtcagatgg tggggtgaaa aagcatcgtt
     3661 aaagatcgga agattttgtt ctatcgcaga cggcgttgaa atatttcttg gagggaacca
     3721 ccgctcagat tggataacaa cttacccttt ttccgccatc gcccactggc ccgaggccga
     3781 aaatataccc ggacacccag cgaccagggg cgatgtcatt atcggaaatg acgtttggat
     3841 cgcgagccat gccatgatcc attctggtgt aaggatcggg gacggagcgg tcataggggc
     3901 aggaagcgta gtccggcgtg atgttccgcc atacgcactc gttgcgggaa atcccgcaga
     3961 gactgtgcga ctgcgttttt ccgagaggga ggtcgcaact ttactcaaga ttcgctggtg
     4021 ggattgggag gaagaacgaa tccgtgaaac ccttcccatt ctcctatcag gaaatatttc
     4081 gctgttcttc gatgcctgcg gcatcccaaa ggagctcttt tcttagactg cttcgctagc
     4141 aagcccgatt ctctggacgt gcggcagagt cctcccgatc tcgatcttgt tcgccgcatg
     4201 tgctgtctgc acagcaactt gcataccgcc ttaagcgacg ttcgatgggg ttgcggcacg
     4261 ccctgcgatg ggcgccaaga agtaattgtt gttcaacgga aaaagttgtt ggacagaagc
     4321 tcgtcacccc aggagaaagt tcccgatgac gctccgcacc acacctcgat gggtatgttt
     4381 ggacaaagga gcataagctg acgaacaggc gaaagttcag tatacttgcg gccgtctcgt
     4441 tggctaccag cttggcacca gctgcgctgc tgagccgctc tcggaaagcc tacgcagcca
     4501 tgcgccctaa aactccctcg gcccgcccac agccaaccct cctcaccgcg cccgtcgagc
     4561 ttgccggcga ctggggccgc atgcttgagg gcgcggctga tcaggtcgtc gagcgaatgc
     4621 ggcatgcctg cctcgacggc gtccgccttg tctccgaccg ccagccgacg cggctgcgtg
     4681 tcgacgaaca cacttctggt acgccggcca tctggctgca tccggacggc accagcatgg
     4741 cctggatcat cgtggacatc ggcgagcggg actggtcgaa gctcgcctac cagttcggcc
     4801 acgagctcgg ccatgtgctc tgcaacagct ggcaaccgga cgccaggccg gcgccgccat
     4861 gccaatggct cgaggaggcc atggtggagg cccactcgct gcgcgggctc gggcgtctgg
     4921 caagaagctg gaaggaggcc ccgcccttcg ccggcgacaa cgccttcggc gatgccatcg
     4981 cccgataccg ccaggatatc atcgaccgct atacggctct cgccgatagc caggggctca
     5041 cccgcgacgc cgcggcgtgg ttcaccgatc atcgcggcga gatcgaaatg cccgccctta
     5101 atccgttcgc ccaggctatg tcgctgacca tcctcgccga atacgaccgc gcgccggact
     5161 gcatcgaggc gctgggggca ctcaaccgct ggcccggccg cagcggcctg gccattggtg
     5221 aatatctgcg gcaatgggag gcgagctgcg ccgagctaca ggcttcgccc agattaccgg
     5281 tccgcctgcg cgagctgttg cgcatcgtct gatcagcagc aaacccgcca cccgtgatct
     5341 ccggaaaccg cacggaacca gcagggggca aaggcttcgc gacgatcgaa aaggctccga
     5401 gcgggcttcg gttcagcctt gtcgccaaag cgagtatggt tttccaccgt taactctttg
     5461 gatcgagttt tcttgctggc gcttcggtga ctcgtttatt agagacccct tatggagaga
     5521 cggcacgcaa tccgaagggt cagtgatggg ctctgggagg tctacgacat agacaacaac
     5581 aaggttgtgc gcgtgggtgg agtgcccttg acaaacttgt tggatgaaga cgcgctcgac
     5641 gcgttggacc tgataaggga tggcttcctg acccttggtc agcccaagag gacaaaggcg
     5701 taagcaaggt gccagttcag ggcgactggt cgggcgacgg aagttgcaat cccaggtgca
     5761 gacgctgatt cacagcgaaa gcgacggcat cggactcacg ttcgaaggct ctagaatagg
     5821 tgtggccgtc cgctgttacg atcgtaacaa cccactcgcc caaggattgg ctgatttcta
     5881 cagttgcggg cgacggtttg gtgtcggcca tgctcctgct ttaaaaactg acggttaagc
     5941 aatgtctcac gaagtccgtc gtccccctat taggggcccc ggcgagtttt cgccacgtca
     6001 tccgatcatt gaactggcaa atttccgttg gaggttgccc ggaatggcgc ccgacggacg
     6061 gcccgctttt caggtccgcc gcacctcaca catatggatc gtcgacctcc ttatcatcgg
     6121 tcatccgttc gcgcctggcg attgtgtaag cgaatactcg cccatcattt tcgtcagtca
     6181 cccggaccca atctttctcc catttttggg agattgatct gcgtgaattc atgatcaatg
     6241 cagccgcgtc tggactacat gcttcgactg ccttcgacct aacaattcga tcgagacgca
     6301 tctctgctac atcgtaaatt ggcatagtac acccccaaca acccgcactt ctccaagagc
     6361 agtattgctc agtataggaa cggccgcaag tggtgggcgt tggacctgca aacgtgcgaa
     6421 atcttgctta cgccaaggag gtgggcgcga aaggtttggg tttaccggat ggactatgag
     6481 gtcggccgca ttcttacaag gcgtgattgc caaagcgcga ttaaggcttg cgtgctaggg
     6541 gtgggactat ttttgctttt cgcttcacag ggcctttctt cgccggcgcc gccttccgac
     6601 cgagtccggc cgcctttgcc aactccgttc gcggtggcga cggcgctgga tgttgcggtt
     6661 tgccaggacg tctgggctta ggccgtcgca tgtctgcctc tggaatttgg gggtgagttc
     6721 cgccaaccca caggcgagag gtcctgagca gccgtcgcac gttccggcga tcgccgctct
     6781 gtaatttgtg ctctgtcata cttttgatag tatgccctgt cagcgagggt gacatgtcgc
     6841 atgagagccg agttgatgtt ccgaacgcgg ggactggctc gcgccttccg atcggcaggg
     6901 ggttgatgga cgacggcgtc gaggcccgtc atgagcggcg cgttctaacc gccctttgtt
     6961 acgatctcgt aggctccacc gagttgctcg gcctgctcgg catcgaagat tttgaggaac
     7021 ttatcttggc gtttcaaatg gccgccaagg aagcgatcgt atcgtgctcc ggaaccgtga
     7081 gggtcgaagt cggcgacggc ggcgtcgctg tgttcccagt cgatctgggt gcgaaggatg
     7141 cggcgtcgct gacgatcagc gccggacttg agatcgtcag ggcgtgcaag ctccttgccg
     7201 cggagaaagg gaggagcgac ctacatgtga gggtcggtgt ggcgacctcg atgacgctaa
     7261 tcctgaaggg cgacaccggt gtagcgcagg acacggtaac cggccctgca tttgcgctgg
     7321 caactaggct gcaggcaatc gcccggccag atactgtcgt cgtgtgcaac gagacacgca
     7381 acctgacacg gcgttcacac gtatttagct tctgcggttc tcacgtcatc aaaggcttcg
     7441 cgcaacccga gcaggtctgg caggcgctga gccacaagcg gggtgtagac cgtttcttcg
     7501 cgttcggacg cctcaccagc cccttgatcg accgcacgga tgaggccaag ttgatacgtg
     7561 aatgttggaa tgaagccgtt tcgggacgtg gccaggtcat cgtgatcgag ggcgaagccg
     7621 gcattggcaa gtcgcgcatc ctgcacgagg tgcgccggcg aacccgcttc caacgcaaca
     7681 ggttgctcct cttccaatgt atgccaggcg actcgcgttc gacgctgcat ccactgcggc
     7741 aggcgatgct gggcaatttc gacgacggcg agcgtgcact cactcctgcg cttgtggccg
     7801 aggtgttcgc cgcacatggc gttcacgacc ccgaagtcgt cgacatcttt tcctttctgc
     7861 tcggcgtgga aggcgtgagg tccagtttcc atgagatgga tccggaaatg atccgggaga
     7921 aggccgaatg ggctgcacgc catgcgttac aagcaacgtg cgccagtggc gcggtgatct
     7981 tgatcgttga agatattcac tggatcgacc tgacgtcgaa gcaactgctg ggtgaacttg
     8041 caaagctggt ccctagttgc cccgtgctct tgatcgcaac gacgaggccg gaatctggcg
     8101 tctggctaga cgaaaaaagc aagcatgtcc tgctcgctcc ccttgagcat gctgacacgt
     8161 tgcgggcaat cgcaacgatg tggcctcaag gcaagccagc gcctgcgcct gagctgaaag
     8221 agttggtcga gcgcgtcacc ggcggtgtac ccctgttcat cgaggaggtt tgccaatgga
     8281 tggcggagaa tgccgctagc ggtacagagc aactgccaca gggcgtttcg ctcggccgcg
     8341 cggccgtgtt ggaaacagtg ttagatgccc ggctggagcc tctcggccgc gcccgcgagg
     8401 tggcgcgtgc ggccgccgtc gccggcaaca gattcagcct ggacttgctg tcggcgctct
     8461 tgccggaatt tgacccaggc acaatctctg cggcgctcga tgccctggtt gaggcaggct
     8521 tcgtacgcgc cagacacgca gcagcaacag tgtacgcatt tcggcatgcg cttatccaag
     8581 agacgatcta taatgcaacg ctgcggaaac ggcgtcagac tctgcatcgg cgtctttatg
     8641 cggtggctag ccgcaaccgc agcctcgttg gctggctaac aacggcagct cttgccgatc
     8701 atgctgagcg agcaggcctg cttgacgaag cgatcggcga gttcgtcaat gccggcatgg
     8761 aaagctcgtc ccgctcggcc atggctgagg caaggcagct gctcgagcat gccattgcgc
     8821 tttgcgggca agtttctgat catgacaaac gggatgcgct gcggctctcg gcgatggtgg
     8881 cgctcgggcc gatactgacc gccgtcgaag ggccaaattc cgagcacgcc cgcatgctct
     8941 atgacgaagg cgtaaagatc gcacggcgtc ggccgatagc ggagcgcgcc aaatggttcc
     9001 caatctattg gggttggtgg ttcacgggtt cggtcgttga tggcgagcgg gcgcaggccg
     9061 tcgtcagtga tctaaaggag gttaacgacc ccgagattca gcttcaggct aggcactgct
     9121 tatgggcagt cgatttcaat cgcggagacc atggtggatg catagccgcg attgattctg
     9181 gattgccgct ctatgacgtg ggccaggggc acgcgaatgc cacgcgtttt ggggggcacg
     9241 acgcgcgcgt gtgcggcttg gcgcatcgtg cactgtcgct gtggttttcg ggacgtgcaa
     9301 cgagcgctct ccgctccatg tcggaggccc gtcgctgggc gcagcggact ggccatgtca
     9361 gcagcattgc gcatgcctgt atcaacgacg cgatgctgag ttgctatcgc cgcgacttcg
     9421 cttcgttgcg taacgtgatt gaggatctgc gacagctgac cgcgcttcat cacctgcctt
     9481 cgctggtcgt ctcggcacaa atcttcgagg gctggtgcga tggcaacgct ggccagcttg
     9541 agcggggcaa ggacaagatg cgcgagggcc tcggcctgca tggacaagtg cagacacccg
     9601 aggacgagcc agtctattgc ggcatgctgg cagaacttct cgcccgctcg ggtgcgatca
     9661 gtcacgcgct tgccctgctt cattcggcgg tggctcaggc cgaggcgggt ggcagccgat
     9721 attggctggc ggaactacac cggcgaattg cacaacttct cgtccttgac agggcgccgg
     9781 ccggccgggt ggcagctgcc cttgagcaga gcctcaatac tgcagccgag caaaatgccg
     9841 ttcccatcct catcgcggcc tacgagacgc tcagcgcgtc aaatctctcg cccgggctgc
     9901 ttcggagcta caacgaccgt gtcgaagcgg caaggaagtc ggttgagccc ggcgagccgc
     9961 tgatcgtgaa ccctgagccg gaactgcggg ccggccgata gtggaacact atgagcgcgt
    10021 tggtcctccg gcagacgaag cgctgaccta tctgatgtcg atgcgacaag cgttgggcat
    10081 cacccgtatt gcggacatta ccggcctgga ccgtgttggc atcccggtcg tgcaggcaac
    10141 gaggccgttc tcgctttcaa acgcggtcgc gcagggaaag ggcgccagcc tggcccgcgc
    10201 tgcgatatcg gcaattttgg aatccgctga agggtttttc gcagagcgca tcgaatattt
    10261 tgacgtcatc cacggttcgg ccaagtcgct cgagataccc tccgggcgat atgaaacttg
    10321 gctacgagag cctacgcttg ctgattggcg cgacaaggat acggcctggg tctcagcgga
    10381 gaacctgctg gggggcaaat gcgacttcgt tccgctggaa ttggtgcaca cggcctatct
    10441 cgtaccgccc agcccctgtg acggaatttt cacgccaacg acaaccggac tggcggccgc
    10501 gcttgatgaa acagacgcca tcacacacgg catattggag tgcgtcgaac gtgatgcgat
    10561 cgcccgcgct ctccagaccc atggttttct gcaacaccag cgaatcgatc cagcgaccat
    10621 cgatgacgca agggtcttgg ccctattggg tgaacttgca cgaaaggaca tgatcgtcgg
    10681 cctttggctt gcgccatcgc ctgttggcct gcctgtgatt tggtgccatt tgatggagag
    10741 caatcctcgc gagacggcat tgctccatct gccagccgat ggctcggccg ctgcattcga
    10801 tccggcggca gctgccgtcc aagcgattcg cgaggcggcg caggcgcggc ttgcggcgat
    10861 ctcgggtgcg cgcgatgaca tgacccgggc gtcttatccg agatatcccg actggcagct
    10921 tatcgaggcg caccgccagc tgatcaccgg cggccgtaag gacgtgagct tcgcccgcca
    10981 gcgtgcctat cgagcggcgg gcggacagac cttgcgtggc agccttctcg cgagattgga
    11041 ggaaagcgga atcaatgccg tgtatctgat ccgtctaaac accagccctt ggaaccgact
    11101 gtcggtcgtc aggatggtta tcccccaatt gtaccctttg gtggagtgag cggatgcgac
    11161 ctcggctcgt tttcaccggc cctacgctat cgcatccaga ggcacagcag gtggccgacg
    11221 tgatctgtct ggcgcccgcg gtgcaaggct cgatcgtagc tgcggtgcaa cgttatgacc
    11281 ccgctgcaat tgtcatcata gacggcgctt tccaggctga gccggcagtg aggcacaagg
    11341 agatactgtg ggcgatcagc cagggcatcc cggtgatagg tgctggaagc atgggagcct
    11401 tgcgagccgc ggagctttac ccatacatgc acggcgttgg ccttatctac cgatggtacc
    11461 gccgctttgc tgtcctgcct gatgacgcag tggcagtgct ctatggtccg aaggcggtga
    11521 atttctcgcc actaacgcac gctttggttg atttgcgaat gaccgtccgc gttgcttgga
    11581 ggcggaacct gatctccacc gatttgtccg gaaagctcga gggtgcggcc cggaacctca
    11641 attttcggga acgcacgctg tcgcgaatgg tccgcgaggc attgccggaa gccggtgacc
    11701 atgacttgca aacctgccgg caaattctcg caggagcttt cgttcaccaa aagaagcgcg
    11761 acgcactgtc agctctacaa tttatgcacg aaaatgcatt ggtgccggcg gaattgaaaa
    11821 atttcagaat gacggtcggg ttcgcccaag atttggagga cgccgggtta gcagtctgac
    11881 gacagagttg ccgctcatac ttggtgcatt ttacgaagta caggcttcgt gctagtgtcg
    11941 cagactatga gaggggccgc gcagttgaac gagcttgatg tcgccggtcg ggcggggatg
    12001 tcggccggaa cgcgcttcct gctataccca caagcgcctt acgtttctgg ttacgagaaa
    12061 cctgaggtgg tctggatttc aacatcgcct ggtttgatcc atccaggccc ggaggatcat
    12121 cgtatatacg tgcgtgatcc cgtgctggcc aagcagccgt acgagtatcc ctacctgccg
    12181 cccttcgtcg gcgcgtattt cccaccagcc gaacccggct ttgatggtca tttcgacaac
    12241 ctctctcttc actcgcgccc gttcctggca gcgcatgcgt tcgcggccgc gagtcgggtg
    12301 ctggacatct gggaaagcta tctgggcaaa ccgattgtct ggtacttcgc cgaaacatac
    12361 gagcggcttg agatcattcc ctggattgac tgggagaatg cgcaatcggg gtatggctat
    12421 ctggagcttg gccgcgagcg tggagccgac gggcgcggcc atccgtacgc cctcaacttc
    12481 gacgtgatcg cgcatgaaat gggtcactca atactctttt ctctcttcgg agtgcccacg
    12541 aaaggcctgc aggacggcga cttcgggccg ttccacgaag ccaacgccga tcttatttcg
    12601 ctgctttcgt tcctgcattt cgacagcggg atggatcgat tgttacggca cagccaggca
    12661 aacctgcttg tcctcaacga gctcaaccgc atcggcgaac tgacgggcga ccgccagatc
    12721 cgccttgcca gtaactcgcg caagatgacg gaagtaaccg aagagattca tgaccggtct
    12781 cgcccattca cgggagcgat cttcgatacc ctggtcgatc tctaccatgc cggcttggtg
    12841 cggcagggcc tggccgacga gcgcctgctt cgcttcgaca tcaggcaggt tagtgaagcc
    12901 gatatgcggc gcatctctaa cttcacgggc gatgcgttcc gggcccgtcc cttccttttc
    12961 aagaccgagc taatcaaggc gcgcgacgat gtcgcgcttt cgctcgcgcg cgcgtggacg
    13021 cgcctcgatg ccgaccatct cacattcgca atcgcagcct ccaccatcat cgaagtgtcc
    13081 gaccgcttcc gcccggccgt ggcggcaagc ttcgaggaga acttcaggtg gcgggaaata
    13141 ttatgaactg gtgattgcaa cggaggagta acaacatgag tgacgatttt caccgaccga
    13201 cactgacttt tcccggtggc gcatataacg ccagccaagt aaggctctac ggcatccccg
    13261 ggagtggcgg tctcgtgttc ccagggagct caaaggccgt cggcacaaag aacacaagta
    13321 tttcttcaaa catgtctact ggagacctca aaaaagatga aaaagcaaat gctgaaataa
    13381 ataaaatatt agaaggctta agagctgcag gagaaaatat attatctgac gaagaaatat
    13441 tcaaaacact tattaccacg ccgccatttc catggcctgt aggaatgtcg taccaaattg
    13501 ccctcgacac gcgaaatttt ggaaaaattg ctttatcaac gttattaaca atcgaagagg
    13561 cggcaaggga aagaaaattg ctgtcttgtg gtattattgt gggttattcc tatgaaggac
    13621 attgctatga cctaccaaaa ccaaaaatca tgttgatctc cgcctttcct caagaaattc
    13681 cagccgacga ttgcggctat gacaagaaaa atgatcagcc gagtgtggcg gatagataca
    13741 tgctttggat tgtcgacaag ctcgacgagt gcattgaatt cgaaacgaac caggggttcg
    13801 tcgagcagat cgttctcgaa gccaatatgc cgggtaagcg ctcgcccacg atgtatgctt
    13861 cccggatgat gatggggcac cgcgggggaa gacttggcga ctgatagaac gagtgcgcgc
    13921 acggccgatc gcgagttgtg gtcggcaagc ccagttcggc tggcagggtt gtcgtccaat
    13981 ccaaccggct atggcgattg tctacgatcc gttcgaaatt atcgaaagcg caatctccgg
    14041 cccgcgcctt cgccagcgga cggctccatg cagaggcgcc caaccatctt ctcgaacgct
    14101 cttcaagggt cacagacttg gtcgaagagc gatttgcgag gcttcggtca atgttggccg
    14161 ttctaaaggc cctttcaaat catagaggca ccaggacaat gggcgaattc tatgtgatgc
    14221 gcacctccgg tgccgtggtc gtcgaaagag agcgcaccgg tcgaactgtt atagatgata
    14281 tggtcgccac catcatgcgt gcccatgccg gcgaagagag cgccatttgg cggagcgccc
    14341 gtgtgaagcc ccaaagcgtg gtcgtgatga atcttttgtt ggctgaagtc cgtagcccgg
    14401 tcggccctcc cggccgtaag agcagtattg aatgcgaaga catcgctgcc gacatcggcc
    14461 agtgaggcga gtcctctgcg cccgtggcca ccggccgatt ctgtcaccca gtggttggca
    14521 ttggggacat gatggacgcc gtcggttctg tcgatcaaat cggcaccgtt ggtgtgatga
    14581 tgactaccat cgctggggtt ggcgacaact ggagtgctcg gtgtactagc ggtgccaagg
    14641 ctcacatggg tatcgggggt attgggagtg ctaggagtgc taggagtgct aggagtgcta
    14701 ggagtgctag gagtgctgga ggcgccagag gtgctcgggg gaggggtggc agggccgctt
    14761 gcggcgctgc tgagattatg ttgctggaac aaggcttgca gcgccggcga gttgccaagc
    14821 gcggtgtcgc cctgttgaga accccaggca taggcatagt cgaaggcggg cgatggcgcc
    14881 accttggccc agtggtccag catggtctgc tcctgggcga cgctgggaag gacatattgg
    14941 ccgcccgtat cggtggtgta gttgccgccg ccgaacgtct gataaaccgg aacgatctgg
    15001 ctgagcggaa cgcccgaggc gaccgccgcg gccacggtcc tgtcgatcat gttgtagtcg
    15061 acggtgcttg tgccggtgcg caccgggtag ggatccacgc cgtaatagtc gatatgcgtg
    15121 ttggcgggat tgaaagtgtt tgaaaaatcg ggatcagccg aagaccccat gttcatcatg
    15181 gtgatgaagg tcttggcgcc gggcaggttg gtgtggatcc agtcggattc cgccttcaga
    15241 ttgtcggctg tggcataggt tccccatttg cccgtgggat cgggctcgtc gacgaggaag
    15301 aagccgaaca cattcggatt gccgatgaag ggcgtgactt tctgaatgaa ggacgaggtc
    15361 gcgccattgg cttcatcgag ccagaccaga cctttcgtgc cagccggcaa ggcgttgagt
    15421 tcgtccacgg atgaaacgtc gacaagattg aacccggcgg ttgcgacgtc cgtcgctgat
    15481 ccgcctgatg cgtagtggag agtggccatc caatttcctt cgtctgattc gatagcccca
    15541 gtgcctacct agccgaaaac gtatattagc gcacaatcaa atacaggcac tctttgacag
    15601 aatcattgat tgtagacggg ggatcgccac aagataggcg ctatgtggga gatgtgcgcc
    15661 atggactgga cctggaaaca gggcagtaag ggcagcaatc gaggaattgc atctattggc
    15721 gaatgccgtg gggcacggtg atggtcgcgc cgttcgcgaa ctgcggggac ttgcctacgt
    15781 cgcacatgtc gtcgatatga gggtcgatga gttcgccgaa aggtttcagg cgcgctatcg
    15841 gttttgggtc gcccaacgcc gtgcatcgtc tcggcgcagg aaggttccgc tgacgtagcg
    15901 acctttgcga tggacttgga tacgccagga accggacgat agctttgttt aggtggccat
    15961 tttttcgtgt gcgcccagcg cgcgctgaga gatcgaaacg tggcgaaaag ggtcgcattc
    16021 tggcgtaaat tcgtgtgcac ttggcaggtt ctaacaattt gaagaaaaaa tgttgaaata
    16081 tcaagaccat agactggcta ttgcacccat gatggactgg acggaccggc attgccggtt
    16141 cttccatcgc cagctgacga gccgtgcact gctttatacc gagatggtgg tggccgatgc
    16201 tgtgatccat ggcgcgcgcg aacggctgct cggctttgat gacgcggaac atccggtcgc
    16261 gctacagctc ggcggctcgg atccggcgaa acttgccgag gcggcgcgca ttggcgaagc
    16321 cttcggctat gacgaggtca acctcaatgt cggctgtccg tccgatcgcg tccaatcggg
    16381 cactttcggc gcctgcctga tgaaagtgcc tgacctcgtc gccggttgcg tcacggcgat
    16441 gaaggcggcg gtggcaatac ccgttaccgt caaatgccgc atcggcgtcg acgagcagga
    16501 tccggagccg gcgcttgatg cgctggcaga tggggttttc aacgccggcg ccgacgcgct
    16561 ttgggtgcat gcgcgcaagg cttggctgga agggctgagc cccaaggaaa accgcgacat
    16621 cccgccgctc gactataaca gggtctatcg gctgaaagcc aaaaaaccga acgaattcat
    16681 tggtatcaac ggtggcattc aatcacttga agaggcgcgg gcgcatctcg atcatgtcga
    16741 cggcgccatg ctcggccgcg ccgcctacca cacgccaggc attctggccg gcgttgatgc
    16801 cggcttctac ggcgcgaagc ctgaggcgtt cgatttcgcc gcgctgatcg atgccatggc
    16861 ggactatgca gcgcgccaca tcgaacaggg cgggcggctc ggccatgtca cccgccatat
    16921 ggtcgggctg ttccatgggc tgcccggtgc acgccgctac cgtcagatcc tgtccaccga
    16981 cgcaaaccgg cccggcgccg ggcctgacgt gctgaagacg gcgttcgccg ccgtcgaatt
    17041 cagtggagcg gccgccgaag cggcctaggc tcagtcccgc aggatcatgc ggtcgccacg
    17101 cacgtcgaag cccgacagcg agccgatgaa attcatgccg agcaggctct ggctcagcat
    17161 gccgggtgcc gcgaccatca ccggcatgtc cttgcgcacg atgccgccga tcgccaccgc
    17221 atcggtcttg accgcggcgg cgcgcgccat gccgttggct gtcgaaaccg gtatcgtgta
    17281 gttgagcgct gccgggttga agccggcggc ctgggcatct tccgacgtca gcaccgtgct
    17341 ggtcgcgccg gtgtcgacaa cagcccggac cgggttgcta ttgaccagga tgcgcgcttc
    17401 gaaatggccg ttgtcagcct tgtcgagggt cactgtagcg tggccgtcct cgacgccaag
    17461 cgccagcggg ctgccgggaa cgaggcccgc ggtcacccgg ctggcaatgt cctgcagttc
    17521 gtagcgatat tggtagccgg cgatcagcgc cagcacgatt gccgcccagg cgccgaaatt
    17581 ccgggccatg tcgcccaacg ggcggccgga gcgcagcaag ccggcgccga tcagggcacc
    17641 aaaggcgcca agccagatca gccggccaaa atcgtaattc tcgacgccaa gcgtgctgcc
    17701 ggcggaatca ttgagcacga gcagggccgc tcccacgccg atcaccgcca tcagaatcca
    17761 gaacagtcgg ctgctcatcc gttcctcgct agagcaattc caggaaaagg gtgaccggtt
    17821 ttcccataag aattgcgtta aaacaaagag ttggagcggt tcgccgtttc cgtgaaacgg
    17881 tgaactgccc tagagtgcgt cgcgttcgcg cgccatgcgg gtgcggcgcg tttcgcggcg
    17941 cggccggcgc tcgaccgttt ccaaccgggc cggcagttcg gccatcacat tgcggcgcgt
    18001 ttcgggcgtc attcccatcc aggcgccgat ttcctcgcgc gtgcggccgc aaccgaagca
    18061 gaagccggtt ttcatatcga ttgaacagac caggatgcag ggggattcga tggccgtcat
    18121 gactttctct cgagggatcc atgcggactc cgctcttcca ccgacacatg gtgcaacggc
    18181 aaagccaatg caagccctcg cgatcgcgcc ttcccgggcc atctttgcgg caatcaaggc
    18241 ggatgtttgg gagaggttgt gccgatcacg caacgcagct atgccgctca ccaaatccag
    18301 gaatgattgc tcacgacatg accagcgctc tgcctttcga cgattttcgc aacctgctcg
    18361 acaatatgcc ggcagccgat ctcaaagccg aagcgcgcgt gcgcgcgctg tttgccaagg
    18421 ccgacaagcc ggcgcattcg ctcggccgca tcgaggacat cgccgcgtgg cttgccgcct
    18481 ggagcggccg ggctccgccc gcggtgacac ggccgttgat ggcggtcttt gccggcaatc
    18541 acggcgtgac ccgtcatggc atttcgccgc gccccgtggc ggcaaccgcc aacgcggtcg
    18601 agctttgcgc ggcaggcggt gcggcgatca accagatctg cattgcctat gatctgggat
    18661 tgaaggtgtt cgatcttgcc ctgcatatcc cgaccggcga catcgcagag gatgccgcgc
    18721 ttgacgagcg cggatgcgcg gcgaccatgg ccttcggcat ggaagcgatc gccggcggca
    18781 ccgatctgct ttgcctcggc gatctcggcg tcggcaattc caccgtcgcc gccgccctgt
    18841 ttgccgcgct gttcggaggc aggcgtgccg attgggttgg cccgggatcc ggcgccgacg
    18901 cggcaatgca ggcgcgcaag gcggatgtgg tcgatgcggc gctggccttt caccacggcc
    18961 atctcgacga cccgttggaa gtgctgcgcc gggtcggcgg ccgcgagttc gccgcgatag
    19021 ccggcgccat cctcgccgcg cggatgcaga agattcccgt gctgctcgac ggctttgcca
    19081 caacggctgc cgcggcggtg ctttatgccg cgaatcctgg ggccctggat cattgtcttc
    19141 tcgccagcct gtcgccggag cccgcgcata ccagggccgc cgagctgctt ggcttccgtc
    19201 cgctgctcga cctcggcata ggccatggcg aaggggcagg ggctgcactt ggcgcgggcc
    19261 tggtcaaggc ggcggcgcta accagttcag gcatggcggc ggcggttcgg atctaggtgc
    19321 aaggcacacc gggcgctgac gaggtccgtt accgccgtcg cgccgccacc gccgcggtcg
    19381 gcaacgccgg cagttcttcc atcacccggc tcagcgggaa gatggcaatc gcctccgtgc
    19441 cttcacgcag tttggaatga agttcgaact cgccgccatg cattgcaagc aggccttgca
    19501 cgatcggcag gccgagcccg gtgccttgtt cggcgctctt gatggcgatc gagccctggc
    19561 cgaaggccga gagcacgact gggatctcgt cctcgggaat ccccggacca ttgtccttga
    19621 cggagatgta ttgcccgccg cccgccgtcc agccgacgcg gacgcggatt tcgccgccgg
    19681 tggcggtgaa ctttatggca ttggacagaa ggttgagcgt gatctggcgc acggcgcgct
    19741 cgtctgcgaa cagccgcggc aatgtctgtt cgaaatcctg gacgacgcgg atatccttgt
    19801 tgcgcgcctt caactccatc atatggcagc aatcctcgac gatgttgagc aacatcaccg
    19861 gctcttcgtt gagctggtag cgaccggctt ctatgcgcga cagatcgagg atttcgttga
    19921 tcaggtcgag caggtgctgg ccggaatcat gcacgtcatg ggcataatcg cgataggtgg
    19981 gattgctcat cggccccagc acctcgttcg ccataacctc ggaaaagccg agaatggcgt
    20041 tgagtggcgt gcgcaattcg tggctcatcg aagcgaggaa acgcgacttt gccagattgg
    20101 cgtcctcggc ccgccgccgc gcctcgtccg acatggattt cgctgtctcc agctcggcga
    20161 tcagcgcatc cttttcggag cggaacgaca acagcatcag cgaggcgcgg ttgagctgac
    20221 gggcgacata gacgaagaaa ggcagcgaca ggacaagcag cccggccatc atcgcctcga
    20281 ccggcatcca cagcctggta ccgacatagg catagagcgc caccggtacg gcgaaagtcg
    20341 ccagcagcgc gccgctcagc gatgaggcca tgagcgccgt cccggccatg gcaagaagca
    20401 gcaccaccgc cttgaccacc ggaaactggt cgaccgcgca ggcgccgcag ccgagcacga
    20461 cgaaccagcc ccagccgagg ccgcaaagga aatggcctac caggaattcc cgtcgcgttt
    20521 gcaaggggtt aagctcggac gcttccgtgc gctcgatgcg tcgcgccatg aaggcgacga
    20581 tcgtatagca agtgagcgtg aacaacgccc agagcccgat ctcgttgccg acgccggcga
    20641 gccagccggc agcggcgatc gccaggacga gcaacgggat caccacggcg ccgcttgtca
    20701 tggcgccggc atggagtttc aacaattcgc ggtcgaaatc gggattgccg gcctgctgcg
    20761 aaagacggtc gcgcgtcttg cgcaccgcgc gcgccacatc gctgttgcga tggggtttcc
    20821 tgcggtccac aatgaacttg tccgctgtgt tcgagcgttg caagggcatc aaaaacttca
    20881 atttatgcgc gcagcgattt caaggtgtta agctacgttc gaatgattaa ccaaccgttt
    20941 gccatatgag ccgttcttgg tcgccgagat cgcgccggcg gtacgcggcg ccgcgcccga
    21001 ggagcctgtg gcgcaaggtg ctggactatg gactgaccat catcattctg gggctgctga
    21061 tcctgttggc ggcgcgcctg gatcgggtgg agacgcgcca gacgcaaggc gcggccatca
    21121 tcaatgacgg cgattcgatc acgctcggca ccgagcgcat ccgcatgcgc ggcatcgacg
    21181 ctccggaata cactcagacc tgccgcagga acggcgtcga ctatgcctgc ggcacgcttg
    21241 cgcgccagtc gctggtgcgc ctgatcgccg gcaggcccgt cacctgcagc ggctggcagc
    21301 gggatcgcta cggccggttg cttggcgact gcaaggccgg cggcaccgac ctcaaccgcg
    21361 ctcaggtcga agcgggatgg gcggttgcct ttggcgactt cgaaagcgag gaagcaaccg
    21421 cccgcgccgc aaaggtcggt atctgggcgg gtacgttcga tcagccgcag gactggcgcg
    21481 acagccatca cggcgaggtc gtggagcgaa aacacggcac gctggcgtcg atcggcgacg
    21541 ccgtgcggga gatttttcgc ttctggtgag gtgtatcggc ttggaaggaa agggaggatc
    21601 gaaatgaagc tctttgacgg tggccgggcg cccaatccgc ggcgggtacg tgtcttcctc
    21661 gccgaaaagg ggatcgcggt tccgctggtg tccgtcgaca tgggcgcgct ggagcacaaa
    21721 ggccaaacgg tgagttcgcg caaccctttg cagcgcctgc cggtgttgga gcttgacgat
    21781 ggcaccgtca tcaccgaatc cgtcgccatc tgccgctatt tcgaggagtt gcatccagag
    21841 ccggccctgt tcgggcgcgg cgcgctgggc aaggcacag
//
