Select genomic region:
Overview
1.1
1.2
1.3
1.4

### Identified secondary metabolite regions using strictness 'relaxed'

NC_014643.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1 | butyrolactone | 655,100 | 670,962 | cysteoamide | NRP | 18%
Region 2 | T1PKS,furan | 883,520 | 926,450 |
Region 3 | linaridin,lanthipeptide-class-ii | 1,120,729 | 1,170,334 |
Region 4 | NRPS | 2,414,944 | 2,459,176 | perquinoline A / perquinoline B / perquinoline C | Other | 14%

NC_014643.1 - Region 1 - butyrolactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 655,100 - 670,962 nt. (total: 15,863 nt) Show pHMM detection rules used
butyrolactone: AfsA

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | butyrolactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000231.1 |  | 0.25 | Polyketide | griseusin | Streptomyces griseus
BGC0001535.1 |  | 0.25 | Other | branched-chain fatty acids | Streptomyces filamentosus
BGC0000286.1 |  | 0.22 | Polyketide | viguiepinol | Streptomyces sp. KO-3988
BGC0000914.1 |  | 0.22 | Other | methylenomycin A | Streptomyces coelicolor A3(2)
BGC0001534.1 |  | 0.22 | Other | branched-chain fatty acids | Streptomyces filamentosus
BGC0000272.1 |  | 0.21 | Polyketide | spore pigment | Streptomyces collinus
BGC0002008.1 |  | 0.21 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000248.1 |  | 0.21 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0000219.1 |  | 0.21 | Polyketide, Saccharide | elloramycin | Streptomyces olivaceus
BGC0000886.1 |  | 0.21 | Other | allylmalonyl-CoA | Streptomyces tsukubensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000231.1 |  | 0.58 | Polyketide | griseusin | Streptomyces griseus
BGC0001535.1 |  | 0.58 | Other | branched-chain fatty acids | Streptomyces filamentosus
BGC0000286.1 |  | 0.55 | Polyketide | viguiepinol | Streptomyces sp. KO-3988
BGC0000914.1 |  | 0.54 | Other | methylenomycin A | Streptomyces coelicolor A3(2)
BGC0001534.1 |  | 0.54 | Other | branched-chain fatty acids | Streptomyces filamentosus
BGC0000272.1 |  | 0.54 | Polyketide | spore pigment | Streptomyces collinus
BGC0002008.1 |  | 0.54 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000248.1 |  | 0.54 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0000219.1 |  | 0.54 | Polyketide, Saccharide | elloramycin | Streptomyces olivaceus
BGC0000886.1 |  | 0.53 | Other | allylmalonyl-CoA | Streptomyces tsukubensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_014643.1 - Region 2 - T1PKS,furan
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 883,520 - 926,450 nt. (total: 42,931 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
furan: (mmyO or AvrD)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T1PKS | furan | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0001909.1 |  |  | 0.62 | Polyketide | strobilurin | Strobilurus tenacellus
BGC0001161.1 |  |  | 0.61 | Polyketide | 1-heptadecene | Moorea bouillonii PNG
BGC0000027.1 |  |  | 0.53 | Polyketide | ankaflavin, monascin, rubropunctatine, monascorubrin | Monascus pilosus
BGC0000099.1 |  |  | 0.52 | Polyketide | monascorubrin | Talaromyces marneffei
BGC0000863.1 |  |  | 0.50 | Other | eicosapentaenoic acid | Pseudoalteromonas sp. DS-12
BGC0001338.1 |  |  | 0.49 | Polyketide | citrinin | Monascus ruber
BGC0001723.1 |  |  | 0.49 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0000862.1 |  |  | 0.48 | Other | eicosapentaenoic acid | Shewanella pneumatophori
BGC0000154.1 |  |  | 0.47 | Polyketide | stipitatic acid | Talaromyces stipitatus ATCC 10500
BGC0000861.1 |  |  | 0.47 | Other | eicosapentaenoic acid | Shewanella sp. BR-2

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001161.1 |  | 0.65 | Polyketide | 1-heptadecene | Moorea bouillonii PNG
BGC0001909.1 |  | 0.64 | Polyketide | strobilurin | Strobilurus tenacellus
BGC0000027.1 |  | 0.60 | Polyketide | ankaflavin, monascin, rubropunctatine, monascorubrin | Monascus pilosus
BGC0000099.1 |  | 0.59 | Polyketide | monascorubrin | Talaromyces marneffei
BGC0001163.1 |  | 0.59 | Polyketide | 1-heptadecene | Moorea producens 3L
BGC0001162.1 |  | 0.59 | Polyketide | 1-heptadecene | Moorea producens JHB
BGC0000863.1 |  | 0.58 | Other | eicosapentaenoic acid | Pseudoalteromonas sp. DS-12
BGC0001338.1 |  | 0.58 | Polyketide | citrinin | Monascus ruber
BGC0001723.1 |  | 0.58 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0001831.1 |  | 0.57 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 883519 - 926450:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (mal)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_822: mal
  PKS_AT (521..793): mal
  ATSignature: Malonyl-CoA
  Top 3 matches:
    Malonyl-CoA: 75.0%
    inactive: 66.7%
    Methylmalonyl-CoA: 54.2%
  minowa: Malonyl-CoA
  Prediction, score:
    Malonyl-CoA: 68.3
    Methoxymalonyl-CoA: 34.8
    Methylmalonyl-CoA: 30.6
    inactive: 20.2
    fatty_acid: 13.5
    Ethylmalonyl-CoA: 12.3
    CHC-CoA: 8.7
    Isobutyryl-CoA: 8.4
    2-Methylbutyryl-CoA: 3.2
    trans-1,2-CPDA: 0.0
    Benzoyl-CoA: 0.0
    Acetyl-CoA: 0.0
    3-Methylbutyryl-CoA: 0.0
    Propionyl-CoA: -1.5
ctg1_826: pk
  CAL_domain (171..484): pk
  minowa: NH2
  Prediction, score:
    NH2: 58.0
    Acetyl-CoA: 21.3
    AHBA: 16.1
    shikimic_acid: 0.0
    fatty_acid: 0.0

NC_014643.1 - Region 3 - lanthipeptide-class-ii,linaridin
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,120,729 - 1,170,334 nt. (total: 49,606 nt) Show pHMM detection rules used
linaridin: (cypemycin or cypI)
lanthipeptide-class-ii: cds(LANC_like and DUF4135)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Lanthipeptides
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | linaridin | lanthipeptide-class-ii | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0000554.1 |  |  | 0.65 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001391.1 |  |  | 0.61 | RiPP | thusin | Bacillus thuringiensis serovar rongseni
BGC0001311.1 |  |  | 0.59 | RiPP | flavecins | Ruminococcus flavefaciens FD-1
BGC0000517.1 |  |  | 0.59 | RiPP | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0000552.1 |  |  | 0.58 | RiPP | SmbA, SmbB | Streptococcus mutans
BGC0001407.1 |  |  | 0.58 | RiPP | bicereucin | Bacillus cereus SJ1
BGC0001210.1 |  |  | 0.56 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0000555.1 |  |  | 0.56 | RiPP | staphylococcin C55 α, staphylococcin C55 β | Staphylococcus aureus
BGC0000497.1 |  |  | 0.54 | RiPP | BHT-Aα, BHT-Aβ | Streptococcus ratti
BGC0000500.1 |  |  | 0.54 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001391.1 |  | 0.67 | RiPP | thusin | Bacillus thuringiensis serovar rongseni
BGC0001311.1 |  | 0.66 | RiPP | flavecins | Ruminococcus flavefaciens FD-1
BGC0000554.1 |  | 0.66 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000517.1 |  | 0.66 | RiPP | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0000552.1 |  | 0.66 | RiPP | SmbA, SmbB | Streptococcus mutans
BGC0000555.1 |  | 0.64 | RiPP | staphylococcin C55 α, staphylococcin C55 β | Staphylococcus aureus
BGC0000497.1 |  | 0.63 | RiPP | BHT-Aα, BHT-Aβ | Streptococcus ratti
BGC0001407.1 |  | 0.62 | RiPP | bicereucin | Bacillus cereus SJ1
BGC0001210.1 |  | 0.62 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0000504.1 |  | 0.61 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Lanthipeptide predictions
Lists the possible core peptides for each biosynthetic enzyme, including the predicted class. Each core peptide shows the leader and core peptide sequences, separated by a dash.

#### Lanthipeptide(s) for ctg1_1033 - Putative Class II

ctg1_1025 leader / core peptide
  MNVSDLANSIEIDTTPGA - ADYAMNDhaAQPDhaMDhb DhbPAGVYAVAEMAVAGDha DhbICLVC
ctg1_1032 leader / core peptide
  MPQDITLLEEISEQDLSQVNGG - DhbAFPGWYDhaKVIGNRGRVC DhbVDhbVECMDhaVCQ
ctg1_1035 leader / core peptide
  MAKDITLLEEISDLDLDQVNGS - GHGGGGYDhaAGGGYDhaGGGNGGGGNYCGNGCGNYNFGFGFWGGDha Dha Dha

#### Lanthipeptide(s) for ctg1_1036 - Putative Class II

ctg1_1032 leader / core peptide
  MPQDITLLEEISEQDLSQVNGG - DhbAFPGWYDhaKVIGNRGRVC DhbVDhbVECMDhaVCQ
ctg1_1035 leader / core peptide
  MAKDITLLEEISDLDLDQVNGS - GHGGGGYDhaAGGGYDhaGGGNGGGGNYCGNGCGNYNFGFGFWGGDha Dha Dha

#### Lanthipeptide(s) for ctg1_1045 - Putative Class II

ctg1_1046 leader / core peptide
  MDSISLIAEVSDQELAGT - VGDQAGGLFDhbVPGDhb Dhb DhbVGHFC DhbIDhaWEC DhaGFICGK
allorf_1154776_1154850 leader / core peptide
  MYITTRHHEGGA - CIYLLHLKC DhbVA
allorf_1155122_1155292 leader / core peptide
  LTILEHIRQA - Dhb CDDhb C DhaYVEYIIVDhaDFYIQVNIDha Dha DhaPKANFMGYLDhbILLDhbLC CIPDhaE
allorf_1168629_1168715 leader / core peptide
  MACSHRVRNRIRCTSAIGA - CLLRPKQC Dhb

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
Lanthipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

ctg1_1025 - Class II
  Cleavage pHMM score: -1.80
  RODEO score: 0
  Monoisotopic mass: 3354.6 Da
  Molecular weight: 3356.9 Da
  Number of bridges: 1
  Additional modifications: AviCys
  Additional modifications: OH
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3374.9 Da N = 1
    3392.9 Da N = 2
    3410.9 Da N = 3
    3429.0 Da N = 4
ctg1_1032 - Class II
  Cleavage pHMM score: -0.60
  RODEO score: 0
  Monoisotopic mass: 3070.5 Da
  Molecular weight: 3072.6 Da
  Number of bridges: 2
  Additional modifications: AviCys
  Additional modifications: OH
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3090.6 Da N = 1
    3108.7 Da N = 2
ctg1_1035 - Class II
  Cleavage pHMM score: -0.60
  RODEO score: 0
  Monoisotopic mass: 3851.5 Da
  Molecular weight: 3853.9 Da
  Number of bridges: 1
  Additional modifications: AviCys
  Additional modifications: OH
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3871.9 Da N = 1
    3889.9 Da N = 2
    3907.9 Da N = 3
ctg1_1046 - Class II
  Cleavage pHMM score: -6.20
  RODEO score: 0
  Monoisotopic mass: 3348.6 Da
  Molecular weight: 3350.8 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3368.8 Da N = 1
    3386.8 Da N = 2
    3404.8 Da N = 3
    3422.8 Da N = 4
allorf_1154776_1154850 - Class II
  Cleavage pHMM score: -7.20
  RODEO score: 0
  Monoisotopic mass: 1357.7 Da
  Molecular weight: 1358.7 Da
  Number of bridges: 1
allorf_1155122_1155292 - Class II
  Cleavage pHMM score: -7.30
  RODEO score: 0
  Monoisotopic mass: 4976.4 Da
  Molecular weight: 4979.7 Da
  Number of bridges: 4
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    4997.8 Da N = 1
    5015.8 Da N = 2
    5033.8 Da N = 3
    5051.8 Da N = 4
    5069.8 Da N = 5
    5087.9 Da N = 6
allorf_1168629_1168715 - Class II
  Cleavage pHMM score: -7.10
  RODEO score: 0
  Monoisotopic mass: 1042.6 Da
  Molecular weight: 1043.3 Da
  Number of bridges: 1
ctg1_1032 - Class II
  Cleavage pHMM score: -0.60
  RODEO score: 0
  Monoisotopic mass: 3100.5 Da
  Molecular weight: 3102.6 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3120.6 Da N = 1
    3138.7 Da N = 2
ctg1_1035 - Class II
  Cleavage pHMM score: -0.60
  RODEO score: 0
  Monoisotopic mass: 3881.5 Da
  Molecular weight: 3883.9 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3901.9 Da N = 1
    3919.9 Da N = 2
    3937.9 Da N = 3

NC_014643.1 - Region 4 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,414,944 - 2,459,176 nt. (total: 44,233 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001615.1 |  | 0.33 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0001437.1 |  | 0.28 | NRP | obafluorin | Pseudomonas fluorescens
BGC0001710.1 |  | 0.28 | NRP | obafluorin | Pseudomonas fluorescens
BGC0000417.1 |  | 0.26 | NRP | rhodochelin | Rhodococcus jostii RHA1
BGC0001833.1 |  | 0.24 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0000410.1 |  | 0.24 | NRP | pseudomonine | Pseudomonas fluorescens
BGC0000460.1 |  | 0.24 | NRP | vulnibactin | Vibrio vulnificus CMCP6
BGC0001132.1 |  | 0.24 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001131.1 |  | 0.23 | NRP | ambactin | Xenorhabdus miraniensis
BGC0001128.1 |  | 0.23 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001615.1 |  | 0.66 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0001437.1 |  | 0.61 | NRP | obafluorin | Pseudomonas fluorescens
BGC0001710.1 |  | 0.61 | NRP | obafluorin | Pseudomonas fluorescens
BGC0000417.1 |  | 0.60 | NRP | rhodochelin | Rhodococcus jostii RHA1
BGC0001833.1 |  | 0.58 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0000410.1 |  | 0.57 | NRP | pseudomonine | Pseudomonas fluorescens
BGC0000460.1 |  | 0.57 | NRP | vulnibactin | Vibrio vulnificus CMCP6
BGC0001132.1 |  | 0.57 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001131.1 |  | 0.57 | NRP | ambactin | Xenorhabdus miraniensis
BGC0001128.1 |  | 0.56 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 7, location 2414943 - 2459176:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (ser)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_2103: ser
  Search NORINE for peptide: strict or relaxed
  AMP-binding (520..959): ser
  NRPSPredictor2: ser
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      ser
    Single AA prediction:
      ser
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHISLVDK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      100% (strong)
ctg1_2105: dhb
  Search NORINE for peptide: strict or relaxed
  AMP-binding (54..466): dhb
  NRPSPredictor2: dhb
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aromatic
    Large clusters prediction:
      dhb, sal
    Small clusters prediction:
      dhb, sal
    Single AA prediction:
      dhb
  Stachelhaus prediction details:
    Stachelhaus sequence:
      TMPSQGVVNK
    Nearest Stachelhaus code:
      dhb
    Stachelhaus code match:
      100% (strong)