GCF_002887555.1_ASM288755v1_genomic - 8 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP025799.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS-like,hserlactone	93,550	156,667	indigoidine	NRP	60%
Region 2	NRPS,thioamitides,RiPP-like	1,083,056	1,130,989	s56-p1	NRP	11%
Region 3	transAT-PKS,NRPS	1,563,746	1,639,915	cichopeptin	NRP	38%
Region 4	siderophore	1,753,940	1,773,122
Region 5	thiopeptide	2,111,813	2,138,451	O-antigen	Saccharide	14%
Region 6	NRPS	3,147,012	3,195,735	turnerbactin	NRP	38%
Region 7	betalactone	3,956,152	3,979,940
Region 8	cyanobactin	4,232,348	4,254,309

NZ_CP025799.1 - Region 1 - NRPS-like,hserlactone

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Location: 93,550 - 156,667 nt. (total: 63,118 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
hserlactone: Autoind_synth

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001343.1	0.46	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0000375.1	0.45	NRP	indigoidine	Streptomyces chromofuscus
BGC0000427.1	0.43	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001591.1	0.42	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.42	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0000343.1	0.39	NRP	enterobactin	Pseudomonas sp. J465
BGC0000340.1	0.39	NRP	echoside A, echoside B, echoside C, echoside D, echoside E	Streptomyces sp. LZ35
BGC0001964.1	0.38	Polyketide	alkylpyrone-407, alkylpyrone-393	Cystobacterineae bacterium
BGC0000957.1	0.36	NRP, Polyketide	mycotrienin I	Streptomyces sp. XZQH13
BGC0001833.1	0.36	NRP	icosalide A, icosalide B	Burkholderia gladioli

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001778.1	0.64	Other	showdomycin	Streptomyces showdoensis
BGC0001343.1	0.62	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0000340.1	0.59	NRP	echoside A, echoside B, echoside C, echoside D, echoside E	Streptomyces sp. LZ35
BGC0000375.1	0.59	NRP	indigoidine	Streptomyces chromofuscus
BGC0001897.1	0.58	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0001590.1	0.58	Polyketide	formicamycins A-M	Streptomyces sp. KY5
BGC0000460.1	0.57	NRP	vulnibactin	Vibrio vulnificus CMCP6
BGC0000947.1	0.56	Other	vibrioferrin	Vibrio alginolyticus
BGC0000427.1	0.56	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001591.1	0.56	Other	fatty acid enol ester	uncultured bacterium CSLC2

Similar known gene clusters

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Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 93549 - 156667:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gln)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 93549 - 137036:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gln)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_94

Search NORINE for peptide: strict or relaxed

AMP-binding (228..637): gln

NRPSPredictor2: gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAWQFGLInK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 90% (moderate)

ctg1_115

Search NORINE for peptide: strict or relaxed

AMP-binding (10..404): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DmmFfGacVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 50% (weak)

ctg1_116

Search NORINE for peptide: strict or relaxed

AMP-binding (21..415): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: gly, ala
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: DvyViCTVAK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 70% (weak)

ctg1_118

Search NORINE for peptide: strict or relaxed

AMP-binding (11..419): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DyypttMrCK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 40% (weak)

NZ_CP025799.1 - Region 2 - NRPS,RiPP-like,thioamitides

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Location: 1,083,056 - 1,130,989 nt. (total: 47,934 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))
thioamitides: ((YcaO or TIGR03882) and TfuA)
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000585.1	0.43	RiPP	microcin C7	Escherichia coli
BGC0001488.1	0.41	Other	4-formylaminooxyvinylglycine	Pseudomonas fluorescens WH6
BGC0000887.1	0.41	Alkaloid	saxitoxin, gonyautoxin 2, gonyautoxin 3, toxin C2, toxin C3, gonyautoxin 5, decarbamoylsaxitoxin, decarbamoylgonyautoxin 2, decarbamoylgonyautoxin 3	Dolichospermum circinale AWQC131C
BGC0000928.1	0.40	Other	T3 toxin	Cylindrospermopsis raciborskii T3
BGC0000188.1	0.40	Alkaloid	saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2	Cylindrospermopsis raciborskii T3
BGC0001540.1	0.40	Other	CC-1065	Streptomyces zelensis
BGC0000719.1	0.39	Saccharide	tobramycin	Streptoalloteichus hindustanus
BGC0000720.1	0.35	Saccharide	tobramycin	Streptoalloteichus tenebrarius
BGC0000925.1	0.35	Other	quinolobactin	Pseudomonas fluorescens
BGC0000917.1	0.34	Other	molybdenum cofactor	Rhodobacter capsulatus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000890.1	0.59	Other (Aminocoumarin)	pentabromopseudilin	Pseudoalteromonas phenolica O-BC30
BGC0000258.1	0.59	Polyketide	prodigiosin	Serratia sp.
BGC0001465.1	0.59	Other	bromopyrroles/bromophenols	Marinomonas mediterranea MMB-1
BGC0000891.1	0.58	Other (Aminocoumarin)	pentabromopseudilin	Pseudoalteromonas luteoviolacea 2ta16
BGC0000259.1	0.58	Polyketide	prodigiosin	Serratia marcescens
BGC0000347.1	0.56	NRP	equibactin	Streptococcus equi subsp. equi
BGC0001224.1	0.56	Other	reductasporine	uncultured bacterium
BGC0001334.1	0.55	Alkaloid	caldoniamide A, cladoniamide B, cladoniamide C7, cladoniamide D, cladoniamide E, cladoniamide F, cladoniamide G	Streptomyces uncialis
BGC0001687.1	0.55	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSL12
BGC0000427.1	0.54	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413

Similar known gene clusters

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 4, location 1083055 - 1130989:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (cys)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 5, location 1083055 - 1125716:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_993

Search NORINE for peptide: strict or relaxed

AMP-binding (515..901): cys

NRPSPredictor2: cys

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLwNMSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 90% (moderate)

ctg1_994

Search NORINE for peptide: strict or relaxed

AMP-binding (27..391): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: lqymWGGIvK
Nearest Stachelhaus code:: orn
Stachelhaus code match:: 50% (weak)

NZ_CP025799.1 - Region 3 - NRPS,transAT-PKS

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Location: 1,563,746 - 1,639,915 nt. (total: 76,170 nt) Show pHMM detection rules used

transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))
NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000389.1	0.80	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0001050.1	0.78	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0000427.1	0.77	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001128.1	0.72	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001833.1	0.71	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001135.1	0.71	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001132.1	0.70	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0000375.1	0.69	NRP	indigoidine	Streptomyces chromofuscus
BGC0000426.1	0.67	NRP	sevadicin	Paenibacillus larvae
BGC0000901.1	0.66	Other	ferrichrome	Aspergillus niger

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001050.1	0.72	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0000389.1	0.72	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0000427.1	0.71	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001128.1	0.69	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001833.1	0.68	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001135.1	0.68	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001132.1	0.68	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0000375.1	0.67	NRP	indigoidine	Streptomyces chromofuscus
BGC0000426.1	0.67	NRP	sevadicin	Paenibacillus larvae
BGC0001104.1	0.66	NRP, Polyketide	myxovirescin A1	Myxococcus xanthus DK 1622

Similar known gene clusters

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 8, location 1563745 - 1639915:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ccmal - mal - ccmal) + (X - gly) + (ser) + (val)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 9, location 1563745 - 1624507:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ccmal - mal - ccmal) + (X - gly) + (ser) + (val)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 10, location 1599962 - 1639915:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ccmal - mal - ccmal) + (X - gly) + (ser) + (val)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_1422

PKS_AT (6..282): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 66.7%; 2-Methylbutyryl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 111.8
Methoxymalonyl-CoA: 49.8
inactive: 40.5
Methylmalonyl-CoA: 32.3
Propionyl-CoA: 22.9
2-Methylbutyryl-CoA: 13.0
CHC-CoA: 9.9
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

PKS_AT (312..589): mxmal

ATSignature: (unknown)

No matches above 50%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 30.3
Methylmalonyl-CoA: 28.7
inactive: 24.4
Isobutyryl-CoA: 11.1
2-Methylbutyryl-CoA: 9.8
Propionyl-CoA: 8.9
Malonyl-CoA: 5.9
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ctg1_1423

Search NORINE for peptide: strict or relaxed

AMP-binding (271..667): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAgALaGimK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 60% (weak)

AMP-binding (1365..1767): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLVWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

ctg1_1424

Search NORINE for peptide: strict or relaxed

AMP-binding (566..974): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHVSLIDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

ctg1_1425

Search NORINE for peptide: strict or relaxed

AMP-binding (571..978): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DALWfGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 90% (moderate)

NZ_CP025799.1 - Region 4 - siderophore

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Location: 1,753,940 - 1,773,122 nt. (total: 19,183 nt) Show pHMM detection rules used

siderophore: IucA_IucC

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001713.1	0.32	Other	ochrobactin	Ochrobactrum anthropi
BGC0001499.1	0.32	Other	aerobactin	Pantoea ananatis
BGC0000295.1	0.31	NRP	acinetoferrin	Acinetobacter haemolyticus
BGC0001453.1	0.29	Other	desferrioxamine	Streptomyces argillaceus
BGC0000942.1	0.28	Other	petrobactin	Bacillus anthracis str. Ames
BGC0000940.1	0.28	Other	desferrioxamin B, desferrioxamine E	Streptomyces coelicolor A3(2)
BGC0000946.1	0.28	Other	vibrioferrin	Vibrio parahaemolyticus
BGC0001531.1	0.28	Other	bisucaberin B	Tenacibaculum mesophilum
BGC0000941.1	0.27	Other	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000853.1	0.26	Other	ectoine	Streptomyces anulatus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001713.1	0.65	Other	ochrobactin	Ochrobactrum anthropi
BGC0001499.1	0.65	Other	aerobactin	Pantoea ananatis
BGC0000295.1	0.64	NRP	acinetoferrin	Acinetobacter haemolyticus
BGC0001453.1	0.63	Other	desferrioxamine	Streptomyces argillaceus
BGC0000942.1	0.62	Other	petrobactin	Bacillus anthracis str. Ames
BGC0000940.1	0.62	Other	desferrioxamin B, desferrioxamine E	Streptomyces coelicolor A3(2)
BGC0000946.1	0.62	Other	vibrioferrin	Vibrio parahaemolyticus
BGC0001531.1	0.61	Other	bisucaberin B	Tenacibaculum mesophilum
BGC0000941.1	0.61	Other	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000853.1	0.60	Other	ectoine	Streptomyces anulatus

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NZ_CP025799.1 - Region 5 - thiopeptide

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Location: 2,111,813 - 2,138,451 nt. (total: 26,639 nt) Show pHMM detection rules used

thiopeptide: ((YcaO or TIGR03882) and ((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or PF07366 or PF06968 or PF04055) or thiostrepton)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Thiopeptides

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000784.1	0.26	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0000781.1	0.16	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0000928.1	0.15	Other	T3 toxin	Cylindrospermopsis raciborskii T3
BGC0000188.1	0.15	Alkaloid	saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2	Cylindrospermopsis raciborskii T3
BGC0000923.1	0.14	Other	paerucumarin	Pseudomonas aeruginosa PAO1
BGC0000775.1	0.12	Saccharide	lipopolysaccharide	Legionella pneumophila
BGC0001285.1	0.10	Other (Fatty acid)	pseudopyronine A, pseudopyronine B	Pseudomonas putida
BGC0001302.1	0.08	Other	lomofungin	Streptomyces lomondensis
BGC0001127.1	0.07	NRP	jagaricin	Janthinobacterium agaricidamnosum
BGC0000981.1	0.07	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E6

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000784.1	0.59	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0000781.1	0.47	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0000928.1	0.46	Other	T3 toxin	Cylindrospermopsis raciborskii T3
BGC0000188.1	0.46	Alkaloid	saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2	Cylindrospermopsis raciborskii T3
BGC0000923.1	0.43	Other	paerucumarin	Pseudomonas aeruginosa PAO1
BGC0000775.1	0.40	Saccharide	lipopolysaccharide	Legionella pneumophila
BGC0001285.1	0.35	Other (Fatty acid)	pseudopyronine A, pseudopyronine B	Pseudomonas putida
BGC0001302.1	0.31	Other	lomofungin	Streptomyces lomondensis
BGC0001127.1	0.30	NRP	jagaricin	Janthinobacterium agaricidamnosum
BGC0000981.1	0.28	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E6

Similar known gene clusters

Thiopeptide predictions

No core peptides found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

Thiopeptides

Core peptide predictions

No core peptides found.

NZ_CP025799.1 - Region 6 - NRPS

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Location: 3,147,012 - 3,195,735 nt. (total: 48,724 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615.1	0.33	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001185.1	0.31	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0000410.1	0.28	NRP	pseudomonine	Pseudomonas fluorescens
BGC0000401.1	0.27	NRP	paenibactin	Paenibacillus elgii B69
BGC0000423.1	0.25	NRP	scabichelin	Streptomyces scabiei 87.22
BGC0001833.1	0.24	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0000349.1	0.23	NRP	erythrochelin	Saccharopolyspora erythraea NRRL 2338
BGC0001825.1	0.23	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001844.1	0.23	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001790.1	0.23	NRP	sulfazecin	Pseudomonas acidophila

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615.1	0.66	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001185.1	0.64	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0000410.1	0.61	NRP	pseudomonine	Pseudomonas fluorescens
BGC0000401.1	0.60	NRP	paenibactin	Paenibacillus elgii B69
BGC0000423.1	0.58	NRP	scabichelin	Streptomyces scabiei 87.22
BGC0001833.1	0.57	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0000349.1	0.57	NRP	erythrochelin	Saccharopolyspora erythraea NRRL 2338
BGC0001825.1	0.56	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001844.1	0.56	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001790.1	0.56	NRP	sulfazecin	Pseudomonas acidophila

Similar known gene clusters

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Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 13, location 3147011 - 3195735:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-X - ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_2815

Search NORINE for peptide: strict or relaxed

AMP-binding (533..943): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DsWdmGyIDK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 60% (weak)

AMP-binding (2065..2468): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

ctg1_2820

Search NORINE for peptide: strict or relaxed

AMP-binding (35..438): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 100% (strong)

NZ_CP025799.1 - Region 7 - betalactone

Download region GenBank file

Download region SVG

Location: 3,956,152 - 3,979,940 nt. (total: 23,789 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001859.1	0.20	Other (Phosphonate)	fosfomycin	Pseudomonas syringae
BGC0001294.1	0.18	Other	7-prenylisatin	Streptomyces sp. MBT28
BGC0000904.1	0.16	Other	FR-900098	Streptomyces rubellomurinus
BGC0001441.1	0.14	Other	belactosin A, belactosin C	Streptomyces sp.
BGC0000207.1	0.14	Polyketide	chartreusin	Streptomyces chartreusis
BGC0000597.1	0.13	RiPP	SWA-2138	Streptomyces sp. e14
BGC0001464.1	0.13	Other	tetrabromopyrrole	Pseudoalteromonas sp. PS5
BGC0000595.1	0.13	RiPP	SCO-2138	Streptomyces coelicolor A3(2)
BGC0000596.1	0.13	RiPP	SLI-2138	Streptomyces lividans TK24
BGC0001150.1	0.13	Polyketide	pamamycin-607	Streptomyces alboniger

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001859.1	0.53	Other (Phosphonate)	fosfomycin	Pseudomonas syringae
BGC0001294.1	0.49	Other	7-prenylisatin	Streptomyces sp. MBT28
BGC0000904.1	0.46	Other	FR-900098	Streptomyces rubellomurinus
BGC0001441.1	0.44	Other	belactosin A, belactosin C	Streptomyces sp.
BGC0000207.1	0.43	Polyketide	chartreusin	Streptomyces chartreusis
BGC0000597.1	0.42	RiPP	SWA-2138	Streptomyces sp. e14
BGC0001464.1	0.42	Other	tetrabromopyrrole	Pseudoalteromonas sp. PS5
BGC0000595.1	0.42	RiPP	SCO-2138	Streptomyces coelicolor A3(2)
BGC0000596.1	0.42	RiPP	SLI-2138	Streptomyces lividans TK24
BGC0001150.1	0.41	Polyketide	pamamycin-607	Streptomyces alboniger

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_CP025799.1 - Region 8 - cyanobactin

Download region GenBank file

Download region SVG

Location: 4,232,348 - 4,254,309 nt. (total: 21,962 nt) Show pHMM detection rules used

cyanobactin: (cyanobactin_synth or TIGR03678)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001632.1	0.32	RiPP	kawaguchipeptin A	Microcystis aeruginosa NIES-88
BGC0000858.1	0.24	Other	ectoine	Methylobacter marinus
BGC0000859.1	0.24	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000854.1	0.24	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000857.1	0.23	Other	ectoine	Methylophaga alcalica
BGC0000853.1	0.23	Other	ectoine	Streptomyces anulatus
BGC0000852.1	0.23	Other	ectoine	Sporosarcina pasteurii
BGC0000855.1	0.23	Other	ectoine	Methylomicrobium kenyense
BGC0000860.1	0.23	Other	ectoine	Methylarcula marina
BGC0000856.1	0.23	Other	ectoine	Methylophaga thalassica

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001632.1	0.66	RiPP	kawaguchipeptin A	Microcystis aeruginosa NIES-88
BGC0000858.1	0.57	Other	ectoine	Methylobacter marinus
BGC0000859.1	0.57	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000854.1	0.57	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000857.1	0.57	Other	ectoine	Methylophaga alcalica
BGC0000853.1	0.56	Other	ectoine	Streptomyces anulatus
BGC0000852.1	0.56	Other	ectoine	Sporosarcina pasteurii
BGC0000855.1	0.56	Other	ectoine	Methylomicrobium kenyense
BGC0000860.1	0.56	Other	ectoine	Methylarcula marina
BGC0000856.1	0.56	Other	ectoine	Methylophaga thalassica

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names