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Overview
1.1
1.2
1.3

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_LT629770.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1 | betalactone,T3PKS | 769,908 | 815,264 | microansamycin | Polyketide | 7%
Region 2 | terpene | 1,091,315 | 1,112,223 | carotenoid | Terpene | 28%
Region 3 | RRE-containing | 2,062,592 | 2,083,710 |

NZ_LT629770.1 - Region 1 - T3PKS,betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
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Location: 769,908 - 815,264 nt. (total: 45,357 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | betalactone | T3PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0001962.1 |  |  | 0.70 | Polyketide | hierridin B, hierridin C | Cyanobium sp. LEGE 06113
BGC0001938.1 |  |  | 0.68 | Polyketide | entotheonella | Candidatus Entotheonella serta
BGC0000282.1 |  |  | 0.65 | Polyketide | alkylresorcinol | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001831.1 |  |  | 0.57 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0001483.1 |  |  | 0.40 | Other | 5-isoprenylindole-3-carboxylate β-D-glycosyl ester | Streptomyces sp. RM-5-8
BGC0001444.1 |  |  | 0.40 | Other | caboxamycin | Streptomyces sp. NTK 937
BGC0001935.1 |  |  | 0.38 | Other | 3,7-dihydroxytropolone | Streptomyces cyaneofuscatus
BGC0001487.1 |  |  | 0.38 | Other | 3,7-dihydroxytropolone | Streptomyces cyaneofuscatus
BGC0001080.1 |  |  | 0.37 | Other (Phenazine) | endophenazine A, endophenazine B | Streptomyces anulatus
BGC0000698.1 |  |  | 0.36 | Saccharide | hygromycin A | Streptomyces hygroscopicus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001962.1 |  | 0.68 | Polyketide | hierridin B, hierridin C | Cyanobium sp. LEGE 06113
BGC0001938.1 |  | 0.67 | Polyketide | entotheonella | Candidatus Entotheonella serta
BGC0000282.1 |  | 0.66 | Polyketide | alkylresorcinol | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001831.1 |  | 0.62 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0001444.1 |  | 0.57 | Other | caboxamycin | Streptomyces sp. NTK 937
BGC0000286.1 |  | 0.55 | Polyketide | viguiepinol | Streptomyces sp. KO-3988
BGC0000649.1 |  | 0.55 | Terpene | carotenoid | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001538.1 |  | 0.54 | NRP, Polyketide | caboxamycin | Streptomyces sp. NTK 937
BGC0001483.1 |  | 0.52 | Other | 5-isoprenylindole-3-carboxylate β-D-glycosyl ester | Streptomyces sp. RM-5-8
BGC0001935.1 |  | 0.51 | Other | 3,7-dihydroxytropolone | Streptomyces cyaneofuscatus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_LT629770.1 - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,091,315 - 1,112,223 nt. (total: 20,909 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000644.1 |  | 0.35 | Terpene | carotenoid | Dietzia sp. CQ4
BGC0000650.1 |  | 0.33 | Terpene | carotenoid | Algoriphagus sp. KK10202C
BGC0000648.1 |  | 0.23 | Terpene | carotenoid | Myxococcus xanthus
BGC0000637.1 |  | 0.22 | Terpene | carotenoid | Corynebacterium glutamicum
BGC0000664.1 |  | 0.21 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000649.1 |  | 0.19 | Terpene | carotenoid | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000656.1 |  | 0.18 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000643.1 |  | 0.17 | Terpene | carotenoid | Brevundimonas vesicularis
BGC0000634.1 |  | 0.17 | Terpene | carotenoid | Brevundimonas sp. SD212
BGC0001903.1 |  | 0.16 | Other | neocarazostatin A | Streptomyces sp. MA37

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000644.1 |  | 0.68 | Terpene | carotenoid | Dietzia sp. CQ4
BGC0000650.1 |  | 0.67 | Terpene | carotenoid | Algoriphagus sp. KK10202C
BGC0000648.1 |  | 0.56 | Terpene | carotenoid | Myxococcus xanthus
BGC0000637.1 |  | 0.55 | Terpene | carotenoid | Corynebacterium glutamicum
BGC0000664.1 |  | 0.54 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000649.1 |  | 0.51 | Terpene | carotenoid | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000656.1 |  | 0.50 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000643.1 |  | 0.48 | Terpene | carotenoid | Brevundimonas vesicularis
BGC0000634.1 |  | 0.48 | Terpene | carotenoid | Brevundimonas sp. SD212
BGC0001903.1 |  | 0.47 | Other | neocarazostatin A | Streptomyces sp. MA37

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_LT629770.1 - Region 3 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,062,592 - 2,083,710 nt. (total: 21,119 nt) Show pHMM detection rules used
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001994.1 |  | 0.15 | Other | β-ethynylserine | Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0000925.1 |  | 0.14 | Other | quinolobactin | Pseudomonas fluorescens
BGC0000928.1 |  | 0.14 | Other | T3 toxin | Cylindrospermopsis raciborskii T3
BGC0000188.1 |  | 0.14 | Alkaloid | saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2 | Cylindrospermopsis raciborskii T3
BGC0001774.1 |  | 0.14 | Other | spicamycin | Streptomyces fimbriatus
BGC0000916.1 |  | 0.13 | Other | molybdenum cofactor | Staphylococcus carnosus
BGC0000879.1 |  | 0.05 | Other | toyocamycin, sangivamycin | Streptomyces rimosus
BGC0001808.1 |  | 0.04 | Other | toyocamycin | Streptomyces diastatochromogenes
BGC0000881.1 |  | 0.04 | Other | toyocamycin | Streptomyces ahygroscopicus subsp. wuzhouensis
BGC0000409.1 |  | 0.04 | NRP | porothramycin A | Streptomyces albus subsp. albus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001994.1 |  | 0.45 | Other | β-ethynylserine | Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0000925.1 |  | 0.44 | Other | quinolobactin | Pseudomonas fluorescens
BGC0000928.1 |  | 0.44 | Other | T3 toxin | Cylindrospermopsis raciborskii T3
BGC0000188.1 |  | 0.44 | Alkaloid | saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2 | Cylindrospermopsis raciborskii T3
BGC0001774.1 |  | 0.43 | Other | spicamycin | Streptomyces fimbriatus
BGC0000916.1 |  | 0.42 | Other | molybdenum cofactor | Staphylococcus carnosus
BGC0000879.1 |  | 0.21 | Other | toyocamycin, sangivamycin | Streptomyces rimosus
BGC0001808.1 |  | 0.19 | Other | toyocamycin | Streptomyces diastatochromogenes
BGC0000881.1 |  | 0.19 | Other | toyocamycin | Streptomyces ahygroscopicus subsp. wuzhouensis
BGC0000409.1 |  | 0.18 | NRP | porothramycin A | Streptomyces albus subsp. albus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names