LOCUS       NZ_LS483429.1           9220 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LS483429.1 Haemophilus aegyptius strain NCTC8502 chromosome 1,
            complete sequence.
ACCESSION   NZ_LS483429
VERSION     NZ_LS483429.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:03:26
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 744425
            Orig. end    :: 753645
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1317
                     /locus_tag="ctg1_771"
                     /transl_table=11
                     /translation="MAFNQDGYAEALGINHFARNSANSTALFDLTLYELGGLAARVVDM
                     PADAAISRSIEIQGDQDDAISNEIERLKILPALADMVRWSRFFGGAVMVLLTDDGARLS
                     EPLEPSRITRIDEVRVFDLSQISPTANRYSDPTKPNYGRYSSYRLNIGTIAGSLDSQVE
                     IHESRLLFMGGDSLPERLKNGLHWIGRSAVRSVYPKIRDYQKSLMWASLILERKQQAVH
                     KMKGLALAIDNGLEPVIRERINLVERGRSLLNGVAVDSEDDYNILNADLGGIVDVLDEF
                     KVAISADVNIPVAILFGQSAKGMNATGQSDFESYYDLVESIQQHKIKPVLEKLIELLMF
                     QKHIKPFENWKIKFPSLNTPTDKEIADVRKTNADAAKIELDRLINLVDSGALSTEELRT
                     QIAGEFGIQADKLPQVDDDDVEKYQEEQKAKGVVVSSRN"
     protocluster    1..9220
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[748630:749578](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4206..5153
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..9220
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9220
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     PFAM_domain     88..1131
                     /aSDomain="DUF1073"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06381.13"
                     /description="Protein of unknown function (DUF1073)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_771_0001"
                     /evalue="4.10E-91"
                     /label="ctg1_771"
                     /locus_tag="ctg1_771"
                     /protein_end="377"
                     /protein_start="29"
                     /score="305.5"
                     /tool="antismash"
                     /translation="LTLYELGGLAARVVDMPADAAISRSIEIQGDQDDAISNEIERLKI
                     LPALADMVRWSRFFGGAVMVLLTDDGARLSEPLEPSRITRIDEVRVFDLSQISPTANRY
                     SDPTKPNYGRYSSYRLNIGTIAGSLDSQVEIHESRLLFMGGDSLPERLKNGLHWIGRSA
                     VRSVYPKIRDYQKSLMWASLILERKQQAVHKMKGLALAIDNGLEPVIRERINLVERGRS
                     LLNGVAVDSEDDYNILNADLGGIVDVLDEFKVAISADVNIPVAILFGQSAKGMNATGQS
                     DFESYYDLVESIQQHKIKPVLEKLIELLMFQKHIKPFENWKIKFPSLNTPTDKEIADVR
                     KTNADAAK"
     CDS             1256..2515
                     /locus_tag="ctg1_772"
                     /transl_table=11
                     /translation="MLKSIKKNRKPKAWLFPHAIEREYVGYLRGVARNINTMVNQKFVE
                     IRPHFQANIRQDSFSDILERWLIELLQAVLIFVDEKEITQFVRGYVKQTADFNRRQFHK
                     VLKSVYSVDVFTTEPWLDDALKIAEWENIRLIKSLPTQTLEKLRSRFTQAVRGGWRWES
                     VVDDVKSILNTNEKRATLIARDQIGKLNGHLTKLRQQNIGVKSYIWRGMLDERERAHHV
                     DREGKQFDWDNPPDDGHPGEPILCRCYAEAVFPEFEDLGRDDAEPIDPISTIKTGKMNL
                     DELFDNSLSGGGNKSFSNFGSVDPALVTLAKESIGLDISGWQHSIDESSIRHILKQHGN
                     EKAENKRGQRAVTKADILMLPQIVSSFDSIDYTGTSDAGNETFLLRKEIGDEIFCVQEV
                     RKRHKKIAVKTMWIRKKKKP"
     PFAM_domain     1691..2002
                     /aSDomain="Phage_Mu_F"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04233.16"
                     /description="Phage Mu protein F like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_772_0002"
                     /evalue="2.10E-15"
                     /label="ctg1_772"
                     /locus_tag="ctg1_772"
                     /protein_end="249"
                     /protein_start="145"
                     /score="57.5"
                     /tool="antismash"
                     /translation="KLRSRFTQAVRGGWRWESVVDDVKSILNTNEKRATLIARDQIGKL
                     NGHLTKLRQQNIGVKSYIWRGMLDERERAHHVDREGKQFDWDNPPDDGHPGEPILCRCY
                     "
     aSDomain        1703..2014
                     /aSDomain="TIGR01641"
                     /aSTool="tigrfam"
                     /description="phageSPP1_gp7: phage head morphogenesis
                     protein, SPP1 gp7 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_772_0001"
                     /evalue="5.40E-16"
                     /identifier="TIGR01641"
                     /label="ctg1_772"
                     /locus_tag="ctg1_772"
                     /protein_end="253"
                     /protein_start="149"
                     /score="56.9"
                     /tool="antismash"
                     /translation="RFTQAVRGGWRWESVVDDVKSILNTNEKRATLIARDQIGKLNGHL
                     TKLRQQNIGVKSYIWRGMLDERERAHHVDREGKQFDWDNPPDDGHPGEPILCRCYAEAV
                     "
     PFAM_domain     2186..2509
                     /aSDomain="PBECR3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18812.3"
                     /description="phage-Barnase-EndoU-ColicinE5/D-RelE like
                     nuclease3"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_772_0003"
                     /evalue="3.40E-23"
                     /label="ctg1_772"
                     /locus_tag="ctg1_772"
                     /protein_end="418"
                     /protein_start="310"
                     /score="82.0"
                     /tool="antismash"
                     /translation="AKESIGLDISGWQHSIDESSIRHILKQHGNEKAENKRGQRAVTKA
                     DILMLPQIVSSFDSIDYTGTSDAGNETFLLRKEIGDEIFCVQEVRKRHKKIAVKTMWIR
                     KKKK"
     CDS             2641..3714
                     /locus_tag="ctg1_773"
                     /transl_table=11
                     /translation="MVMRYDRRGIQARRDDNGFIYDTPILTRSGVFVYELPNGKTRREY
                     RPPDEVFKADSLRAYKGLPITEDHHGLVTKNNAHLVVGSILTEGKQDGQNLTADIVIHN
                     TKAVDFGKKELSVGYKVDIDETSGTTEDGEPYDVIQRNIRPNHLAIVTVGRAGNAALNL
                     DAADAVEFNEDGENPMSNTQTTLSDIRLDSGITYQAAPEVIVELNKLKQDAKDAVTAKD
                     KEAARADAAEAKVKELETQVEQIKQDAVSQAKVRVELENVAKVHNVEVKADSTDRALRE
                     AVIKAIRQDDADLSQKSDGYIEAAFDIAVSDAKQREDAAGLQRQQLTPSATNQTTFTQD
                     SQTKLTGRAAMIASRNQ"
     PFAM_domain     2680..3120
                     /aSDomain="DUF2213"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09979.11"
                     /description="Uncharacterized protein conserved in bacteria
                     (DUF2213)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_773_0004"
                     /evalue="1.30E-31"
                     /label="ctg1_773"
                     /locus_tag="ctg1_773"
                     /protein_end="160"
                     /protein_start="13"
                     /score="109.9"
                     /tool="antismash"
                     /translation="RDDNGFIYDTPILTRSGVFVYELPNGKTRREYRPPDEVFKADSLR
                     AYKGLPITEDHHGLVTKNNAHLVVGSILTEGKQDGQNLTADIVIHNTKAVDFGKKELSV
                     GYKVDIDETSGTTEDGEPYDVIQRNIRPNHLAIVTVGRAGNAA"
     CDS             3725..4144
                     /locus_tag="ctg1_774"
                     /transl_table=11
                     /translation="MSMYDQLQQKAFAGMKGDSRYDLVETFAAEAEIPFGVVITQGTKA
                     NQAKLGGTKPIGIALHSHAVVGGYAKFDAVSVLRKGVAWCVVKDSEAITAGSAVSFDPA
                     SGKVAKTGTALPNATFKTAVVDCGKYGKLALVELA"
     CDS             4206..5153
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Linocin_M18"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_775"
                     /sec_met_domain="Linocin_M18 (E-value: 7.9e-07, bitscore:
                     25.3, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDIRQDAFELNAINTCLNAVGVFNQDAGLFTQRQLEFVRNKIYE
                     EKLPGMNGLSLVPVSSEAPEWAETVTERIYDMVGMAKVIANYADDLPRADVAMTERAVK
                     VKNIGAAYGYNLQELKAASANQTDLPSSKARAARRAVEVKMNEIALLGDKEFGLNGFIN
                     HPNLGETSVTGGWKTATADAVLADLDNLHDTVVLQSKGVHQPTHLLLSLTDYQTLSSKY
                     MNTADKVDVLTFFKRKHPNLTIQGLWELEKAGTGNKNLAICYEKSLDNLTLETPQDFTQ
                     LPAQERNLELVVNCVARVGGVFLRYPLSATKAEI"
     PFAM_domain     4440..5144
                     /aSDomain="DUF2184"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09950.11"
                     /description="Uncharacterized protein conserved in bacteria
                     (DUF2184)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_775_0005"
                     /evalue="3.60E-66"
                     /label="ctg1_775"
                     /locus_tag="ctg1_775"
                     /protein_end="313"
                     /protein_start="78"
                     /score="223.2"
                     /tool="antismash"
                     /translation="GMAKVIANYADDLPRADVAMTERAVKVKNIGAAYGYNLQELKAAS
                     ANQTDLPSSKARAARRAVEVKMNEIALLGDKEFGLNGFINHPNLGETSVTGGWKTATAD
                     AVLADLDNLHDTVVLQSKGVHQPTHLLLSLTDYQTLSSKYMNTADKVDVLTFFKRKHPN
                     LTIQGLWELEKAGTGNKNLAICYEKSLDNLTLETPQDFTQLPAQERNLELVVNCVARVG
                     GVFLRYPLSATKA"
     CDS             5156..5344
                     /locus_tag="ctg1_776"
                     /transl_table=11
                     /translation="MIVRNIEARLIRVGGEFIAPNQEVEIADDAVGLDRLIKRGVLIDV
                     TPKAEDAKKDGKSKKQE"
     CDS             5348..5698
                     /locus_tag="ctg1_777"
                     /transl_table=11
                     /translation="MSAYSLLNLFYPLSQQMPEDMVNKALSVADNKRPDCLSDDKQDEA
                     VAWYAAYLLAQSIESGVNAAGLRREREGDLEREYFSGSDKGGNAERFLAKYNELNNICV
                     RLGAITVGSYCV"
     PFAM_domain     5378..5602
                     /aSDomain="DUF4054"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13262.8"
                     /description="Protein of unknown function (DUF4054)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_777_0006"
                     /evalue="1.20E-07"
                     /label="ctg1_777"
                     /locus_tag="ctg1_777"
                     /protein_end="85"
                     /protein_start="10"
                     /score="31.8"
                     /tool="antismash"
                     /translation="YPLSQQMPEDMVNKALSVADNKRPDCLSDDKQDEAVAWYAAYLLA
                     QSIESGVNAAGLRREREGDLEREYFSGSDK"
     CDS             5691..6149
                     /locus_tag="ctg1_778"
                     /transl_table=11
                     /translation="VSSVVKVKINNKGLEKELELINKIGKARVKVGVQADAGVHSESGE
                     NLVDIGIWNEYGTAHIPSRPFIRQTFEDNQQAVAQYLGRVVSNVAKGADLVQELSKLGQ
                     WYQDKQKNTLKSYPWTPNAPSTRRRKKSSKPLVDTSQLVNSIRYKVEI"
     CDS             6149..6508
                     /locus_tag="ctg1_779"
                     /transl_table=11
                     /translation="MQIFSSQSSFRKPYTILVRSDGEYVKGKWVNGGEIEQTLMASIQP
                     LSGVEMDRLVVSMQGRRVSSAVKIYTDQKLTVAGENAHNGTVVLFDGERYEVISRASYH
                     SGVLSHHRYVAIRVK"
     CDS             6510..7019
                     /locus_tag="ctg1_780"
                     /transl_table=11
                     /translation="MLERLYDLLGDLSDRPFIRTYENGREPEKPFFTYELKFERTPEHF
                     HYSAVNDEGNQTVKTHIDAVLELNYFGGNSLQALRDVCMRLSMQSCRERWLNDGVALIR
                     IGRITHLAFLNEQREYEDRAMVELEIRYAASVQDIMGIIEQVEVTANIGRASEKNLIGV
                     NENGEN"
     CDS             7000..8079
                     /locus_tag="ctg1_781"
                     /transl_table=11
                     /translation="MKMAKIDRLVNVAIDLNTTTIAGKSFSDLLILGEHTLNNSARFLV
                     VTDPNELLDLGLKSNNPLYIAVATAFAQPSHVAQVFIGRKAQDESVTDALAAVARENNS
                     WYGLALVSREDADVMLAAAWAETNGKLFVTASADEKLPQSAEKTDIASKLEAKQYYRSA
                     VMYSHKATEEYPEIALMSYSFTFYPGSETWNLKKLAGVSYSPLMEGEYLACSKKNATTF
                     EKFNDSFAVTQGGKVAAGEWIDIIRFRDWLVQEVQINVTSVLINAYGKVPYTDKGIQLI
                     GAAVRQALDLGVARGGIAPTELDDNNKEIPSYVISLPLAAKVSNNNKGKRLLQDVKFSA
                     RLAGAIHLTEIKGNLAYSL"
     PFAM_domain     7258..8061
                     /aSDomain="DUF3383"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11863.10"
                     /description="Protein of unknown function (DUF3383)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_781_0007"
                     /evalue="5.30E-51"
                     /label="ctg1_781"
                     /locus_tag="ctg1_781"
                     /protein_end="354"
                     /protein_start="86"
                     /score="174.2"
                     /tool="antismash"
                     /translation="QDESVTDALAAVARENNSWYGLALVSREDADVMLAAAWAETNGKL
                     FVTASADEKLPQSAEKTDIASKLEAKQYYRSAVMYSHKATEEYPEIALMSYSFTFYPGS
                     ETWNLKKLAGVSYSPLMEGEYLACSKKNATTFEKFNDSFAVTQGGKVAAGEWIDIIRFR
                     DWLVQEVQINVTSVLINAYGKVPYTDKGIQLIGAAVRQALDLGVARGGIAPTELDDNNK
                     EIPSYVISLPLAAKVSNNNKGKRLLQDVKFSARLAGAIHLTEIKGN"
     CDS             8125..8550
                     /locus_tag="ctg1_782"
                     /transl_table=11
                     /translation="MALATYAPDEVSIVIGAVIVSGFADGTFIDIEEMSDGVSSVAGAD
                     GEVARATSADPRKKVTLTLLQTSDTNDVLSELYAADKVSKNATFPIAVKDLRGRSLFAA
                     STAWVVKSAKLELGKEVGSREWTLETADGKLFVGGND"
     PFAM_domain     8206..8520
                     /aSDomain="DUF3277"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11681.10"
                     /description="Protein of unknown function (DUF3277)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_782_0008"
                     /evalue="9.80E-09"
                     /label="ctg1_782"
                     /locus_tag="ctg1_782"
                     /protein_end="132"
                     /protein_start="27"
                     /score="35.4"
                     /tool="antismash"
                     /translation="FIDIEEMSDGVSSVAGADGEVARATSADPRKKVTLTLLQTSDTND
                     VLSELYAADKVSKNATFPIAVKDLRGRSLFAASTAWVVKSAKLELGKEVGSREWTLETA
                     D"
     CDS             8550..9032
                     /locus_tag="ctg1_783"
                     /transl_table=11
                     /translation="MTRSEIQIGESTFFVQKFSVMDQLRIFGDLQKTLVPSLAKVIGFS
                     DEKPKDATSAQLAELAQKSAANFAQGLQDLSQQLSGQELVKLADMLIKPELVTVQRDDF
                     NNGTDKKLSKTDFDLVFDDMSELIELVIFILQLNFSSFFTKFLARLGSVQELVKKA"
     CDS             9068..9220
                     /locus_tag="ctg1_784"
                     /transl_table=11
                     /translation="MIAWRPFLAGKVTLTELNTAGLMDMGELLKINRLLDAVDAMEAKQ
                     MEKNR"
ORIGIN
        1 atggcattta atcaagacgg ctacgccgaa gccttgggga ttaatcattt tgcaagaaat
       61 tctgcaaatt caaccgcact ttttgattta acgttatatg agttaggtgg tttagccgca
      121 cgggtggtcg atatgccagc agatgcggcg atttcacgtt cgattgaaat tcaaggcgat
      181 caagatgatg cgattagcaa tgagattgaa cggttgaaga ttttgcctgc attggcagat
      241 atggtgcgtt ggtcgcggtt ttttggtggt gcggttatgg ttttattgac cgatgacggt
      301 gcgcgattaa gtgagccgtt agagccaagt cgcattacac gtatcgatga agtgcgagtg
      361 tttgatttaa gtcaaatttc gcctacggct aatcgctatt ccgatccaac caagccaaat
      421 tatggtcgct attccagtta tcggttaaat atcggtacga ttgctggttc gcttgatagt
      481 caggtagaaa tccatgaaag ccgtttgtta tttatgggcg gtgattcatt gccagaacgt
      541 ctaaaaaatg gcttacattg gattgggcgt agtgcggtta gatcggttta tccaaaaatt
      601 cgtgattatc aaaaatcatt gatgtgggct tcgttaattc ttgaacgcaa acagcaagcg
      661 gttcataaaa tgaaagggct tgcattggca attgataatg gattagagcc tgttattcga
      721 gagcgtatca atcttgttga acgtgggcgt agtctgttaa atggcgtagc tgttgatagc
      781 gaagacgatt acaacattct caatgcggat ttaggcggga ttgttgatgt gcttgatgaa
      841 tttaaagtag cgatttcggc tgatgtgaat attccagtgg cgattttatt cgggcagtca
      901 gctaaaggta tgaacgccac aggacagagc gattttgaaa gctattacga tttggtcgaa
      961 agtattcaac aacataaaat caagccagtg cttgaaaagc tgattgaact attgatgttt
     1021 caaaagcata ttaagccgtt tgagaactgg aaaatcaaat tcccgtcgct taatacacca
     1081 actgacaaag aaatagccga tgtgcgtaaa acgaatgcgg atgcagcgaa aatcgagctt
     1141 gatcgcttaa ttaatttggt tgattcgggt gcattatcca cagaagaatt gcgaacacag
     1201 attgccgggg agtttggcat tcaagcggac aaattgccac aggtagatga cgatgatgtt
     1261 gaaaagtatc aagaagaaca gaaagccaaa ggcgtggttg tttcctcacg caattgagcg
     1321 tgaatatgtg ggttatttac gtggtgtggc gagaaacatt aatacgatgg ttaatcaaaa
     1381 attcgttgaa attcgaccgc actttcaggc aaatattcga caagatagtt tttctgacat
     1441 acttgaacgt tggcttattg aattattgca agcggtattg atttttgttg atgaaaaaga
     1501 aattacgcaa tttgtgcgtg gttatgtgaa gcaaacggct gattttaatc gcagacagtt
     1561 tcacaaggtg ctgaaatcag tttatagcgt cgatgttttc acgactgaac cttggcttga
     1621 tgatgcatta aaaattgcgg aatgggaaaa tatccgtcta ataaaaagcc ttcctacgca
     1681 gacgttagaa aaattgcgta gtcgctttac tcaagcggtg cgcggtggtt ggcgttggga
     1741 aagcgtggta gatgatgtga agtctatcct taacaccaac gagaaacgtg caacattaat
     1801 tgctcgtgac caaattggca agttaaacgg tcatttgacg aagttgcgcc agcaaaatat
     1861 cggcgtgaag tcgtatattt ggcgcggtat gcttgatgag cgtgagcggg cgcaccacgt
     1921 tgatcgtgag ggtaaacaat ttgattggga taatccacct gatgacggac atccggggga
     1981 gcctatttta tgtcgttgct atgcggaggc ggtattccct gaatttgaag atcttgggag
     2041 agatgacgct gaaccgatag atcctatttc aacaatcaaa acagggaaaa tgaacttaga
     2101 tgagttgttt gataattcat tatccggtgg tggaaataag tcattttcta attttggttc
     2161 ggttgatcct gccttagtta cgcttgctaa agaaagtatt ggattagata taagcggttg
     2221 gcagcatagc attgatgaat cgagtatacg ccatattcta aagcaacacg gaaatgagaa
     2281 agctgaaaat aagcgtgggc aaagagcggt aacaaaagcc gatattttga tgttgccgca
     2341 gattgtttcg tcatttgata gtattgacta cactgggaca agtgatgcgg gaaatgaaac
     2401 gtttttacta cgcaaagaaa ttggagatga aatcttttgc gttcaagaag ttagaaaacg
     2461 ccataagaaa attgcagtaa aaacaatgtg gattcggaaa aagaaaaaac cataaatctc
     2521 acatagtgct tggttcactc tggcacctgc ttaacgtccg aaacgtgcta tgtcctacga
     2581 tttatggttt tctgtattat agagcattga atttaaattt caatttttgg agatcattat
     2641 atggtaatgc gatacgaccg ccgtggcatt caggcacggc gagatgataa cggttttatt
     2701 tatgacaccc ctattctgac aagaagtggg gtgtttgttt atgagcttcc taatggcaaa
     2761 actcgacgtg aatatcgtcc gcccgatgaa gtatttaagg cggatagttt acgcgcttat
     2821 aagggattgc cgattacaga agatcatcac ggacttgtga cgaaaaataa tgcgcatttg
     2881 gtggtgggct ctatcttaac ggaaggtaaa caagatgggc aaaatttaac ggcagatatt
     2941 gtgattcaca atacgaaagc cgttgatttt ggaaaaaaag aattgtcggt tggctataag
     3001 gtagatattg acgagacgag cggtacaaca gaagacggcg agccgtatga tgtgatccag
     3061 cgtaatattc gtcctaacca tttagccatt gtgacagttg ggcgtgcagg caatgccgca
     3121 cttaatttag atgcggcaga tgccgtggaa tttaacgaag atggagaaaa tccgatgagt
     3181 aacactcaaa caacgctttc tgacattcgc ttagatagcg gcattacgta tcaagccgca
     3241 cccgaagtga ttgttgaatt aaataaacta aaacaagacg ccaaagacgc agtgacagca
     3301 aaagacaaag aagcggcacg cgcagatgcg gcagaagcga aagtgaaaga gcttgaaacg
     3361 caggttgaac aaattaaaca agatgcggta agtcaagcca aggtgcgtgt tgaattggaa
     3421 aacgtagcga aagtgcataa tgtggaagtg aaagctgata gtaccgaccg tgcgttgcgt
     3481 gaagcagtaa ttaaggcaat tcgtcaagac gatgcggatt tatcgcaaaa atccgatggt
     3541 tatattgaag cggcgtttga tattgcggta agcgatgcca aacaacgcga ggatgcggca
     3601 ggtttgcagc gtcagcaatt aacaccatct gccacaaatc aaaccacatt cacgcaggat
     3661 agccaaacga aattaactgg tcgtgcggca atgattgcaa gtcgtaacca ataggagcaa
     3721 aacgatgtct atgtacgatc aattacaaca aaaagccttt gctggtatga aaggcgatag
     3781 ccgctatgat ttggtagaaa cttttgcagc agaagcggaa atcccttttg gtgtggtaat
     3841 cacacaaggt acaaaagcta atcaagctaa attaggtggc actaagccca ttggcattgc
     3901 gttacattcc catgctgtag taggcggtta tgcgaaattt gatgcggttt ccgtattgcg
     3961 taaaggggtt gcgtggtgtg tagtgaaaga cagcgaagcg attacggcag gaagtgcggt
     4021 aagttttgac cccgcttcag gcaaggtggc aaaaactggc acagcattac cgaatgcaac
     4081 ctttaaaacc gccgtagtag attgcggtaa atatggcaag ctcgcgttag tcgagttagc
     4141 ttaattattc aatgtttaac gatgccctaa gtgaaaactt ggggcttttt tattggagaa
     4201 aaataatgac agatattcgt caagatgcgt tcgagttgaa tgcgatcaat acttgtttaa
     4261 atgcggtggg tgtatttaac caagatgcgg gcttgtttac gcaacgccaa ttagagtttg
     4321 tgcgcaacaa aatctatgaa gaaaaattac cgggtatgaa tggcttatcg ctcgtccctg
     4381 tctcttctga agcccctgaa tgggcagaaa ccgtgactga acgcatttac gatatggtcg
     4441 gcatggctaa agtcattgcc aactatgccg atgatttacc gcgtgcggat gtggcaatga
     4501 cagaacgtgc ggtgaaagtg aaaaacatcg gtgctgctta tggctacaat ctacaagagt
     4561 tgaaagcggc gtcagctaat caaacggatt taccgtcttc taaagctcgt gcggcgcgtc
     4621 gtgcggtgga agtaaagatg aacgaaattg ccttgttagg agataaagaa tttggtttaa
     4681 acggctttat taaccacccg aatttaggag aaacatcggt aactggtggc tggaaaactg
     4741 caacggcgga tgcggtgcta gcggatttgg acaatctaca cgataccgtc gtgttgcaat
     4801 caaaaggtgt gcatcagcca acacacttat tgttgtcgct aaccgattat cagacgttat
     4861 ccagtaagta tatgaacacg gctgacaaag tggacgtatt gacgttcttc aagcgtaaac
     4921 atcctaactt aactattcag ggcttatggg aattagagaa agcgggtaca gggaataaga
     4981 acttagcgat ttgctatgaa aaatcccttg ataacttaac tcttgaaacg ccgcaagatt
     5041 ttacccagtt accggcacaa gaacgcaatt tagagcttgt tgtgaactgt gtggctcgtg
     5101 tgggcggcgt gttcttacgt tatccgttat cggcaaccaa agcggagatt tagcgatgat
     5161 tgtacgtaat attgaagccc gtttaattcg tgttggcggc gagtttatcg cccctaatca
     5221 agaggtggaa attgccgatg atgcggtagg gcttgatcgt ttaattaaac gtggcgtatt
     5281 aattgacgta acgccgaaag cggaagatgc gaaaaaagac ggcaaaagta aaaagcagga
     5341 gtaataaatg agcgcatact cgttacttaa tctcttttac ccattaagcc aacaaatgcc
     5401 tgaagatatg gtaaataagg cgttaagcgt ggctgataat aaacgtccag actgtttatc
     5461 tgatgacaag caagatgagg cggtggcgtg gtatgcggct tatttgttgg ctcagtcgat
     5521 tgaaagcggg gtaaatgcgg caggtttacg gcgtgaacgt gaaggcgatt tagaacgtga
     5581 atatttttca gggagcgata aaggcggcaa cgctgaacgc tttttggcga aatataacga
     5641 gctaaacaat atttgcgtac gccttggtgc gattaccgta gggagttatt gtgtctagcg
     5701 tggttaaggt aaaaatcaac aataaagggc ttgaaaaaga acttgagttg ataaacaaaa
     5761 tcggcaaagc acgcgtaaaa gtaggcgttc aagcggatgc aggcgttcat tctgaatcag
     5821 gcgaaaactt ggtggatatt ggtatttgga atgaatatgg cacggcacat atcccgtctc
     5881 gtccttttat tcgtcaaacc tttgaagata atcaacaggc agtggcgcaa tacttagggc
     5941 gtgtggtctc taatgtggcg aaaggggctg atttggtgca agagctttca aaacttgggc
     6001 aatggtatca agacaagcag aaaaatacct tgaagtctta tccttggaca ccgaatgcgc
     6061 catctacgcg taggcgcaag aaaagtagta aaccgctcgt agatacctcg caattagtca
     6121 attcaattcg ttataaggtt gaaatctgat gcagatattt tcttctcaat cttcttttcg
     6181 caagccttat acaatacttg tgcgttctga cggagagtac gtgaaaggca agtgggtaaa
     6241 cggcggcgaa atcgagcaga cgttaatggc atccattcag ccgttaagcg gtgttgaaat
     6301 ggatcgccta gtggtatcaa tgcaggggcg gcgcgtttca agtgcggtaa aaatttacac
     6361 cgatcaaaaa ctaacggtgg ctggagaaaa tgcacacaat ggcacagtag tgctatttga
     6421 cggcgagcga tacgaagtga tttcacgagc tagttatcac agtggtgtgt tgtcacatca
     6481 tcgctacgtg gctatacggg taaaataata tgcttgagcg tttgtatgat ttattgggcg
     6541 atctatcgga tcgccctttt attcgcacct atgaaaatgg gcgtgagcca gaaaagccat
     6601 tttttactta tgaactgaag tttgagagga caccagaaca ttttcattat tcggcggtaa
     6661 atgatgaagg caatcagacg gtaaaaactc atatcgatgc cgtgcttgag ttgaattatt
     6721 tcggtggaaa cagtttacag gcattgcgag atgtttgtat gcgcttatct atgcagtctt
     6781 gtcgtgagcg ttggttaaat gatggcgtgg cattgattcg cattgggcgg attacccatt
     6841 tagcctttct aaatgaacag cgtgaatatg aagatcgggc aatggtagag cttgaaattc
     6901 gttatgcggc tagtgtgcag gatattatgg gtattattga acaagtggaa gtgacggcaa
     6961 acataggacg tgcttctgag aaaaatttaa taggggtaaa tgaaaatggc gaaaattgat
     7021 cgcttggtaa atgtggctat tgatttaaat acaaccacaa tcgccggtaa atcttttagt
     7081 gatttattaa ttttaggcga acatacgctg aataattcag cacgttttct ggtagtaacc
     7141 gatccaaatg aattattgga tttaggctta aaatcaaaca atccgcttta tatcgctgtg
     7201 gctaccgcct ttgcgcagcc gtcacacgtg gcacaggtat ttatcggacg taaagcacaa
     7261 gatgaaagcg tgacggatgc gcttgctgcg gtcgcacgag aaaataacag ctggtatggc
     7321 ttggcgttgg tctcgcgtga agacgctgat gtgatgttgg cggcggcgtg ggcagaaacc
     7381 aatggtaaat tatttgttac cgcctctgct gatgaaaaat tgccacaatc ggcggagaaa
     7441 accgatattg cgagcaaact tgaagcgaaa caatattacc gctcggcggt aatgtattcc
     7501 cataaagcaa cggaagaata cccagaaatt gccttaatga gctattcctt cacattctat
     7561 ccggggtcag aaacgtggaa cttgaaaaaa cttgctggcg tatcttattc gccgttaatg
     7621 gaaggcgaat acttagcttg ctcgaagaaa aacgcaacga catttgagaa atttaacgat
     7681 agctttgcgg taacgcaagg cggcaaagtc gcagctgggg aatggatcga tattatccgt
     7741 ttccgtgatt ggttggtgca ggaagtacaa attaatgtga catccgtctt aatcaatgct
     7801 tacggcaaag tgccttacac cgataaaggt attcaattaa ttggtgcggc agtgcgtcag
     7861 gcgttagatt taggtgtagc acgtggcggt attgcgccga cagaattgga tgataataac
     7921 aaggaaattc caagttatgt gatttccctt ccactggcgg cgaaggtgtc gaataacaat
     7981 aaaggtaagc gtttattgca agatgtgaaa ttctcggcac gtttagccgg tgctattcac
     8041 ttaacagaaa tcaagggcaa tctggcttac agtctttaat cattaacaga ccgctaaagt
     8101 gcggtcattt tttaggagaa ttttatggct ttagcaactt atgcgcccga tgaagtaagt
     8161 attgtgatcg gggcggttat tgtttctggc tttgcagatg gaacctttat tgatattgaa
     8221 gaaatgtctg acggcgtatc atctgttgct ggtgcagatg gcgaagtagc acgtgcaacc
     8281 agtgccgatc cacgtaaaaa agtcacatta acgttattac aaaccagtga taccaatgat
     8341 gtgttaagtg aactctatgc agcggataaa gtgagtaaaa acgcaacctt tccaattgcg
     8401 gtaaaagact tgcgtggtcg ctcattattc gctgcaagca cggcgtgggt ggttaaatcg
     8461 gcgaaacttg agcttggaaa agaagtgggt tctcgcgagt ggacgcttga aactgcggac
     8521 ggtaaattat ttgtaggggg aaatgactga tgacacgcag tgaaattcaa attggcgaaa
     8581 gcactttttt tgtgcaaaag ttttcggtaa tggatcagtt acgcattttt ggcgatttgc
     8641 agaaaaccct tgtaccgtca ctggcgaaag taatcggatt tagcgatgaa aaaccgaaag
     8701 atgcaacgtc agctcagtta gccgaattag cacagaaaag tgcggcgaat tttgcgcaag
     8761 gtttacaaga tttaagccag caattaagcg gccaagagtt agttaaacta gctgatatgc
     8821 taattaaacc tgaactagtg acggtgcagc gtgatgattt caacaatggg acagataaaa
     8881 aacttagcaa aactgatttt gatttggtgt ttgatgatat gtcggagctt atcgagttgg
     8941 taattttcat cttacaactt aatttcagca gtttttttac gaaatttctt gcccgtcttg
     9001 ggtcggtgca agagcttgtg aagaaagcgt aagcgttggt aaatacagcg aacagacgct
     9061 aagtgagatg atcgcttggc gtcctttttt agccggtaaa gttacactaa cagagcttaa
     9121 tacggcagga ttgatggata tgggcgagct tttgaagatt aatcgcttac tagatgcggt
     9181 agatgcgatg gaagcaaaac aaatggagaa aaaccgatga
//
