LOCUS       NZ_LR963104.1           9449 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LR963104.1 Aeromonas dhakensis isolate TN14 chromosome 1.
ACCESSION   NZ_LR963104
VERSION     NZ_LR963104.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:44:14
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1611485
            Orig. end    :: 1620934
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1572
                     /locus_tag="ctg1_1497"
                     /transl_table=11
                     /translation="MINPDDVVSLSRLQFGATAMFHFLFVPLTLGLSWILVIAESAYVM
                     TGKVIYKDITRFWGKLFGINFVMGVTTGITLEFQFGTNWAYYSQYVGDIFGTPLAVEGL
                     MAFFLESTLVGLFFFGWDKLSRGQHLLVTMLVALGSNLSALWILIGNGWMQNPVGAEFN
                     LVTQRMELVDVAAVIFNPVAQVKFVHTVAAGYVAASLFVMGVSSWYLLRRMEVRFALRS
                     FAIASGFGLAAILSVIVLGDESGYRTGEVQKVKLAAIEAEWETEPAPAAFTLFGFPDQG
                     AETTHAAIKIPYLMGIIATRSLDEAVTGIKDLKAQHETRIRSGMVAAGALEQIRAGNDS
                     AENRALFDQHGQDLGYGLLLTPYASNIAKAGEAEIARAVEDSVPQVAPLFWGFRIMVGL
                     GVVMLGLFVAGFVQLCRNRLLASSRLLKALLWSIPLPWIAIEAGWFVAEFGRQPWTISD
                     VLPVSASVSLLQPGQLWFSLISICFIYSCLLVVELFLLRRVIRQGPAVLHTGRYSGEQP
                     ELARIA"
     protocluster    1..9449
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1615682:1616543](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4198..5058
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..9449
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9449
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     PFAM_domain     28..1512
                     /aSDomain="Cyt_bd_oxida_I"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01654.19"
                     /description="Cytochrome bd terminal oxidase subunit I"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1497_0032"
                     /evalue="8.00E-168"
                     /label="ctg1_1497"
                     /locus_tag="ctg1_1497"
                     /protein_end="504"
                     /protein_start="9"
                     /score="558.5"
                     /tool="antismash"
                     /translation="LSRLQFGATAMFHFLFVPLTLGLSWILVIAESAYVMTGKVIYKDI
                     TRFWGKLFGINFVMGVTTGITLEFQFGTNWAYYSQYVGDIFGTPLAVEGLMAFFLESTL
                     VGLFFFGWDKLSRGQHLLVTMLVALGSNLSALWILIGNGWMQNPVGAEFNLVTQRMELV
                     DVAAVIFNPVAQVKFVHTVAAGYVAASLFVMGVSSWYLLRRMEVRFALRSFAIASGFGL
                     AAILSVIVLGDESGYRTGEVQKVKLAAIEAEWETEPAPAAFTLFGFPDQGAETTHAAIK
                     IPYLMGIIATRSLDEAVTGIKDLKAQHETRIRSGMVAAGALEQIRAGNDSAENRALFDQ
                     HGQDLGYGLLLTPYASNIAKAGEAEIARAVEDSVPQVAPLFWGFRIMVGLGVVMLGLFV
                     AGFVQLCRNRLLASSRLLKALLWSIPLPWIAIEAGWFVAEFGRQPWTISDVLPVSASVS
                     LLQPGQLWFSLISICFIYSCLLVVELFLLRRVIRQGP"
     aSDomain        1572..2708
                     /aSDomain="TIGR00203"
                     /aSTool="tigrfam"
                     /description="cydB: cytochrome d ubiquinol oxidase, subunit
                     II"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1498_0006"
                     /evalue="6.10E-113"
                     /identifier="TIGR00203"
                     /label="ctg1_1498"
                     /locus_tag="ctg1_1498"
                     /protein_end="379"
                     /protein_start="0"
                     /score="375.8"
                     /tool="antismash"
                     /translation="MDYETLKLIWWGLVLFMLVGFIVMDGFDLGIAMLLPVVSKEDEDR
                     RLVINSVGPVWEGNQVWLIAGAGALFAAWPLVYAAAFSALYVPMIVLLLGLFLRPVGFD
                     YRSKLADPLWRRWWDRALVAGGLVPTLVLSAAIALVMQGLPFRFDSALRLHYGAFDFHW
                     SWIVSVVATGVSLLLLHGASFLQAKVTGTPALRARGLAILLAPLVTLCYLLAGWHLLGL
                     PGYQLTGLAGQPFDPNAAISPLMKGVIPHACGWLGNYFDYPLLWLVPLIGALAPLASGI
                     AAWQEKGRLALLASGLACAAMLCSVAIALFPFVLPSSLDPASSLTLWDGTSSFKTLTIM
                     FGIVLVLMPINLGYTGWVYRVVRGKLDRAGIKRDSHQLY"
     CDS             1572..2711
                     /locus_tag="ctg1_1498"
                     /transl_table=11
                     /translation="MDYETLKLIWWGLVLFMLVGFIVMDGFDLGIAMLLPVVSKEDEDR
                     RLVINSVGPVWEGNQVWLIAGAGALFAAWPLVYAAAFSALYVPMIVLLLGLFLRPVGFD
                     YRSKLADPLWRRWWDRALVAGGLVPTLVLSAAIALVMQGLPFRFDSALRLHYGAFDFHW
                     SWIVSVVATGVSLLLLHGASFLQAKVTGTPALRARGLAILLAPLVTLCYLLAGWHLLGL
                     PGYQLTGLAGQPFDPNAAISPLMKGVIPHACGWLGNYFDYPLLWLVPLIGALAPLASGI
                     AAWQEKGRLALLASGLACAAMLCSVAIALFPFVLPSSLDPASSLTLWDGTSSFKTLTIM
                     FGIVLVLMPINLGYTGWVYRVVRGKLDRAGIKRDSHQLY"
     PFAM_domain     1587..2654
                     /aSDomain="Cyt_bd_oxida_II"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02322.17"
                     /description="Cytochrome bd terminal oxidase subunit II"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1498_0033"
                     /evalue="1.60E-84"
                     /label="ctg1_1498"
                     /locus_tag="ctg1_1498"
                     /protein_end="361"
                     /protein_start="5"
                     /score="283.9"
                     /tool="antismash"
                     /translation="LKLIWWGLVLFMLVGFIVMDGFDLGIAMLLPVVSKEDEDRRLVIN
                     SVGPVWEGNQVWLIAGAGALFAAWPLVYAAAFSALYVPMIVLLLGLFLRPVGFDYRSKL
                     ADPLWRRWWDRALVAGGLVPTLVLSAAIALVMQGLPFRFDSALRLHYGAFDFHWSWIVS
                     VVATGVSLLLLHGASFLQAKVTGTPALRARGLAILLAPLVTLCYLLAGWHLLGLPGYQL
                     TGLAGQPFDPNAAISPLMKGVIPHACGWLGNYFDYPLLWLVPLIGALAPLASGIAAWQE
                     KGRLALLASGLACAAMLCSVAIALFPFVLPSSLDPASSLTLWDGTSSFKTLTIMFGIVL
                     VLMPINLGYTGWVYRV"
     aSDomain        2728..2808
                     /aSDomain="TIGR02106"
                     /aSTool="tigrfam"
                     /description="cyd_oper_ybgT: cyd operon protein YbgT"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1499_0007"
                     /evalue="6.00E-09"
                     /identifier="TIGR02106"
                     /label="ctg1_1499"
                     /locus_tag="ctg1_1499"
                     /protein_end="27"
                     /protein_start="0"
                     /score="34.1"
                     /tool="antismash"
                     /translation="MWYFTWILGLGFALLLGLCNLLWLEAR"
     PFAM_domain     2728..2808
                     /aSDomain="YbgT_YccB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08173.13"
                     /description="Membrane bound YbgT-like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1499_0034"
                     /evalue="4.20E-12"
                     /label="ctg1_1499"
                     /locus_tag="ctg1_1499"
                     /protein_end="27"
                     /protein_start="0"
                     /score="46.0"
                     /tool="antismash"
                     /translation="MWYFTWILGLGFALLLGLCNLLWLEAR"
     CDS             2728..2850
                     /locus_tag="ctg1_1499"
                     /transl_table=11
                     /translation="MWYFTWILGLGFALLLGLCNLLWLEARWEADERDEPRSQP"
     CDS             2929..3888
                     /locus_tag="ctg1_1500"
                     /transl_table=11
                     /translation="MKQTIKAVTLAIGCALATAPAWAEPVQLTPLDKAFTLQVLGSGGP
                     ISDDLRASSSEVVWWKGKSRILIDAGGGVYLRFGQAGAKLEEVDFIGITHFHTDHVTDL
                     PALLKGAYFFKRSDPLDLAGPQAGSAFPSMSGYFDALFNPSKGAYAYLGGFKDGTDGLF
                     PINVHDVPYQTPQPHQVYQQDGLTITALGIPHGDVPCLAYRIESAEGTIVISADQNGSN
                     PAFVPFAKGADILVMPLAIHEGADPVSASLHAKPSVVARIAAEVNPKLLVLNHWMGVGL
                     NHKKEAMAIVKQRFHGQVVAARDLSSYPVSSVKESSHE"
     PFAM_domain     3121..3756
                     /aSDomain="Lactamase_B_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12706.9"
                     /description="Beta-lactamase superfamily domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1500_0035"
                     /evalue="1.20E-15"
                     /label="ctg1_1500"
                     /locus_tag="ctg1_1500"
                     /protein_end="276"
                     /protein_start="64"
                     /score="57.7"
                     /tool="antismash"
                     /translation="RILIDAGGGVYLRFGQAGAKLEEVDFIGITHFHTDHVTDLPALLK
                     GAYFFKRSDPLDLAGPQAGSAFPSMSGYFDALFNPSKGAYAYLGGFKDGTDGLFPINVH
                     DVPYQTPQPHQVYQQDGLTITALGIPHGDVPCLAYRIESAEGTIVISADQNGSNPAFVP
                     FAKGADILVMPLAIHEGADPVSASLHAKPSVVARIAAEVNPKLLVLNHW"
     CDS             3881..4210
                     /locus_tag="ctg1_1501"
                     /transl_table=11
                     /translation="MSNAHSNKSSRKLSLSIAMTGLIALTPGLALAATPSEAPVKAAPS
                     EQHGGKCAAGKCGTEKRFEKQALDSDPQGRLVRARDGKCGLAEQGINGETQRQESKMTE
                     GVCGQ"
     CDS             4198..5058
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1502"
                     /sec_met_domain="DUF692 (E-value: 5e-92, bitscore: 305.9,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPISASSRGVGLRQEHLAQLCAVPARPGIDFLELAPENWMAIGG
                     ARREQLQQIAARYPLVAHGLSLSLGDCQPLNMTLLGQIRAFLDEFGIEIYSEHLSFSRD
                     ARGYLYELLPVPRQWENLPYLAERIRQVQDALARPLVLENISYYHGYEHEMAEEAFLTE
                     LVARSGCELLLDINNVFVNSRNHGYCPERMIAGLPGQAIRYFHIAGHLEEADGTLLDTH
                     GRPVCEEVVALARYTVQTHGLRPLLLERDHHLPPLPVLEAELARVHQACCEVMAHPAGR
                     EVCHD"
     PFAM_domain     4225..5007
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1502_0036"
                     /evalue="7.90E-92"
                     /label="ctg1_1502"
                     /locus_tag="ctg1_1502"
                     /protein_end="270"
                     /protein_start="9"
                     /score="307.3"
                     /tool="antismash"
                     /translation="GVGLRQEHLAQLCAVPARPGIDFLELAPENWMAIGGARREQLQQI
                     AARYPLVAHGLSLSLGDCQPLNMTLLGQIRAFLDEFGIEIYSEHLSFSRDARGYLYELL
                     PVPRQWENLPYLAERIRQVQDALARPLVLENISYYHGYEHEMAEEAFLTELVARSGCEL
                     LLDINNVFVNSRNHGYCPERMIAGLPGQAIRYFHIAGHLEEADGTLLDTHGRPVCEEVV
                     ALARYTVQTHGLRPLLLERDHHLPPLPVLEAELARVHQA"
     CDS             5051..5845
                     /locus_tag="ctg1_1503"
                     /transl_table=11
                     /translation="MTRREQAAWPAAAVPPRLWQQTEWLAGCIRESAVELAPHYVRSVR
                     ANVEAVLESTFALTLNHLTPVERDALVNGFVAHHGAIEPAFHQIATELVRHVQLRQGEG
                     WLNWPGLRLALLEYEWACLCVEIDEAQVPHPLAGEAVEMGSPLWLNPTLQLLTLPFVIQ
                     QGRVVAAGQAPQLCALFRCPAHQLVSQALREFDVALLQLLGQQQGVSVAGLAAQVHPYR
                     SGFDLLGWARHFHRLGLLVTQPPSIEPPSIERQVPPFQGDIP"
     CDS             5842..6456
                     /locus_tag="ctg1_1504"
                     /transl_table=11
                     /translation="MNNTLIHWYERAVAQCKRLDFLALLAIRLYLIPVIYVGAHSKVVG
                     FAGTVAWFGAPASEGGLNLPFPTLLAFLAAGTEVLGCICIALGLFTRVMAIPTIFLMSV
                     ASAMVHWKHGWDAIATGSMEATLRLNGFIEWLAANFPGRYNYITELGDPVMLNNGMEFA
                     ATYFVMLLVLLVLLVYGGGRYVSLDYWLARAVTGKGGPQAA"
     PFAM_domain     5908..6174
                     /aSDomain="DoxX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07681.14"
                     /description="DoxX"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1504_0037"
                     /evalue="2.90E-13"
                     /label="ctg1_1504"
                     /locus_tag="ctg1_1504"
                     /protein_end="111"
                     /protein_start="22"
                     /score="50.3"
                     /tool="antismash"
                     /translation="ALLAIRLYLIPVIYVGAHSKVVGFAGTVAWFGAPASEGGLNLPFP
                     TLLAFLAAGTEVLGCICIALGLFTRVMAIPTIFLMSVASAMVHW"
     CDS             complement(6541..7722)
                     /gene_functions="transport (smcogs) SMCOG1184:major
                     facilitator transporter (Score: 358.2; E-value: 6.9e-109)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_1505"
                     /transl_table=11
                     /translation="MPLALFALTLSAFAIGTTEFVIVGLIPTIAEQLNVSLPSAGLLVS
                     LYALGVAIGAPVLTALTGKVPRKWLLVGLMALFTAGNLLAWQAPGYESLIVARILTGLA
                     HGVFFSVGSTIATGLVAKEKAASAIAIMFSGLTIALVTGVPLGTWIGQVFGWRDTFLVV
                     SLLGLVAMVGSLLLIPNNLPKGAASTIREQLSVLTKKPLLLVYAKTALGYGGAFTAFTF
                     LAPILQQVSGFSAGAVSLILLVYGVSVAVGNIWGGKLADKMGPLPALKLLFAGLAMVLL
                     VLTFTAPHPVLAVLTVLVWGAFAFGNVPGLQVLVVKQAEQHTPRAVDVASGLNIAAFNV
                     GIALGSVVGGLVVEHLGLMHTPWIGALIVLLAYGLTHVSERQATRMAQACPQY"
     PFAM_domain     complement(6754..7698)
                     /aSDomain="MFS_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07690.18"
                     /description="Major Facilitator Superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1505_0038"
                     /evalue="8.00E-43"
                     /label="ctg1_1505"
                     /locus_tag="ctg1_1505"
                     /protein_end="323"
                     /protein_start="8"
                     /score="146.8"
                     /tool="antismash"
                     /translation="TLSAFAIGTTEFVIVGLIPTIAEQLNVSLPSAGLLVSLYALGVAI
                     GAPVLTALTGKVPRKWLLVGLMALFTAGNLLAWQAPGYESLIVARILTGLAHGVFFSVG
                     STIATGLVAKEKAASAIAIMFSGLTIALVTGVPLGTWIGQVFGWRDTFLVVSLLGLVAM
                     VGSLLLIPNNLPKGAASTIREQLSVLTKKPLLLVYAKTALGYGGAFTAFTFLAPILQQV
                     SGFSAGAVSLILLVYGVSVAVGNIWGGKLADKMGPLPALKLLFAGLAMVLLVLTFTAPH
                     PVLAVLTVLVWGAFAFGNVPGLQVLVVKQAEQHT"
     CDS             complement(8303..9103)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     206.1; E-value: 1.2e-62)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1506"
                     /transl_table=11
                     /translation="MKMPNLGLGTFRLTGQPLRDSLLQGLELGYRHIDTAQIYANEAEV
                     GQLMRESGVPRQDIYLTTKVWTSEFGPGKVIPSLEVSLEKLGTDYLDLALIHWPSPRDE
                     VPMAVYLEQLAEAKARGLTREIGVSNFTVAQLKQAIDILGPGAIAHQQVEIHPLLQNRK
                     VVEFCKDHGIAITAYMPLAYGKVLTEPLLMEIGHRHGVSAAQVSLAWLLAQGMTVIPSS
                     TRRENLAANLAALKVTLTADELAAIATLERGERCADPDFAPDWD"
     PFAM_domain     complement(8354..9085)
                     /aSDomain="Aldo_ket_red"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00248.23"
                     /description="Aldo/keto reductase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1506_0039"
                     /evalue="1.40E-46"
                     /label="ctg1_1506"
                     /locus_tag="ctg1_1506"
                     /protein_end="250"
                     /protein_start="6"
                     /score="159.0"
                     /tool="antismash"
                     /translation="GLGTFRLTGQPLRDSLLQGLELGYRHIDTAQIYANEAEVGQLMRE
                     SGVPRQDIYLTTKVWTSEFGPGKVIPSLEVSLEKLGTDYLDLALIHWPSPRDEVPMAVY
                     LEQLAEAKARGLTREIGVSNFTVAQLKQAIDILGPGAIAHQQVEIHPLLQNRKVVEFCK
                     DHGIAITAYMPLAYGKVLTEPLLMEIGHRHGVSAAQVSLAWLLAQGMTVIPSSTRRENL
                     AANLAALKVTLTADELAAIATL"
     CDS             complement(9153..9449)
                     /locus_tag="ctg1_1507"
                     /transl_table=11
                     /translation="MSSPVIVIAQLEAKPEFAPQFRAALDPLIAATLQEAGCLRYQLHQ
                     DLDNPHSWMLYEVWESEAALSAHQGQPHFTEFVTTAEPWFAGSTIRRYQPLDA"
     PFAM_domain     complement(9216..9440)
                     /aSDomain="ABM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03992.18"
                     /description="Antibiotic biosynthesis monooxygenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1507_0040"
                     /evalue="2.30E-22"
                     /label="ctg1_1507"
                     /locus_tag="ctg1_1507"
                     /protein_end="78"
                     /protein_start="3"
                     /score="79.0"
                     /tool="antismash"
                     /translation="PVIVIAQLEAKPEFAPQFRAALDPLIAATLQEAGCLRYQLHQDLD
                     NPHSWMLYEVWESEAALSAHQGQPHFTEFV"
ORIGIN
        1 atgatcaatc cggatgacgt ggtcagcctg tcgcgcctgc aatttggcgc cacggccatg
       61 ttccacttcc tgtttgtgcc cctcacgctg gggctgtcct ggatcctggt gatcgcagag
      121 tcggcctatg tgatgaccgg caaggtgatc tacaaggaca tcacccgttt ctggggcaag
      181 ctgtttggca tcaacttcgt gatgggggtg accacaggca tcaccctgga gttccagttc
      241 ggcaccaact gggcctacta ctcccagtat gtgggggaca ttttcggcac cccgctggcg
      301 gtggaggggt tgatggcctt cttcctcgag tcgaccctgg tgggactctt cttcttcggc
      361 tgggacaagc tctcccgcgg tcaacatctg ctggtgacca tgctggtggc gctcggttcc
      421 aacctctccg cgctctggat cctgatcggc aacggctgga tgcagaaccc ggtgggcgcc
      481 gagttcaacc tggtgaccca gcgcatggag ctggtggacg tggccgcggt gatcttcaac
      541 ccggtggccc aggtcaagtt cgtgcacacg gtggcggcgg gctatgtagc cgcctccctg
      601 ttcgtgatgg gggtgagcag ctggtatttg ctgcgccgca tggaggtgcg cttcgccctg
      661 cgctcctttg ccatcgcctc gggctttggg ctggccgcca ttctctcggt catcgtgctg
      721 ggtgacgagt cgggttatcg caccggcgag gtgcagaagg tcaagctggc cgccatcgag
      781 gcggagtggg agacggagcc cgcgccggcc gccttcaccc tgttcggctt cccggatcag
      841 ggggccgaga ccacccacgc agccatcaag ataccctatc tgatgggcat catcgccacc
      901 cgctccctcg atgaggcggt gaccggcatc aaggatctca aggcccagca cgagacccgc
      961 attcgcagcg gcatggtggc cgccggggcg ctcgagcaga tccgcgccgg caacgactcg
     1021 gccgagaatc gtgcgctgtt cgaccagcac ggtcaggatc tcggctacgg gctgctgctc
     1081 accccctatg ccagcaacat cgccaaggcc ggtgaggccg agatcgccag ggcggtagaa
     1141 gactcggtgc cgcaggtggc gccgctgttc tggggctttc ggatcatggt cgggttgggc
     1201 gtcgtgatgc tcgggctgtt cgtggcgggt ttcgtccagc tctgccgcaa ccggctgctc
     1261 gcctcgtccc gcctgctcaa ggcgctgctg tggagcattc cgctgccctg gattgccatc
     1321 gaggcgggct ggttcgtggc cgagttcggt cgccagccct ggaccatcag cgacgtgctg
     1381 ccggtgtcgg cctcggtgtc gctgctgcag ccgggccagc tctggttcag cctgatctcc
     1441 atctgtttca tttactcctg cctgctggtg gtggagctgt tcctgctgcg ccgcgtgatc
     1501 cgccaggggc ccgccgtgct gcataccggc cgctacagcg gtgaacaacc cgaacttgcg
     1561 aggatcgcct gatggattat gaaaccctga aactcatctg gtgggggctg gtgctgttca
     1621 tgttggtcgg cttcatcgtg atggatggct tcgatctggg catcgccatg ctgctgccgg
     1681 tggtatcgaa agaggatgaa gaccgccgac tggtgatcaa cagtgtgggg ccggtgtggg
     1741 agggcaacca ggtgtggctc atcgccggcg ccggcgccct gttcgccgcc tggccgctgg
     1801 tctacgccgc cgccttctcg gcgctctatg tgcccatgat agtgctgctg cttggcctct
     1861 tcctgcgccc ggtggggttt gactatcgca gcaagctggc tgatcccctc tggcgccgct
     1921 ggtgggatcg cgccctggtg gctgggggtc tggtgccgac cctggtgctc tctgccgcca
     1981 tcgcgctggt gatgcagggc ctgccgtttc gcttcgacag cgcactgcgc ctgcactacg
     2041 gggccttcga tttccactgg agctggattg tcagcgtggt ggcgaccggg gtgagcctgt
     2101 tgctgctgca cggtgccagc ttcctgcaag ccaaggtaac gggcacccct gcactgcggg
     2161 ctcgtggcct cgccatcctg ctggcaccgc tggtgaccct ctgctatctg ctggctggct
     2221 ggcatctgct ggggttgccg ggttatcagc tgaccggcct ggcgggccag ccctttgacc
     2281 ccaatgccgc tatcagccca ctgatgaagg gggtgatccc ccacgcctgc ggctggcttg
     2341 gcaactactt tgactacccg ctgctgtggc tggtgcccct catcggcgcc ctggcaccgc
     2401 tggccagcgg catcgccgcc tggcaggaga agggacggct ggcgctgctg gccagcggcc
     2461 tggcctgcgc cgccatgctc tgctcggtgg ccatcgccct gttccccttc gtgctgccct
     2521 cgtcgctgga tccggccagc agcctgaccc tgtgggacgg cacctccagc ttcaagaccc
     2581 tgaccatcat gttcgggatc gtgctggtgc tgatgcccat caacctcggc tacaccggct
     2641 gggtctaccg ggtggtgcgc ggcaagctgg atcgtgccgg catcaagcgc gacagccatc
     2701 aactctactg accccaaggg agccgctatg tggtacttca cctggatttt gggcctgggt
     2761 ttcgccctgc tgctgggcct gtgcaacctg ctctggctgg aagcacgctg ggaagccgat
     2821 gaacgggatg agccccgctc tcaaccctga tccccctcgg tcggggaggg cagacactgc
     2881 cttgccccga cccctttctc ttgtcatcca accgacaggt aatccgttat gaaacagaca
     2941 atcaaagcgg tgacgctggc catcggctgc gcgctcgcca ccgcgccggc ctgggccgag
     3001 cccgtacaac tgacgccact ggacaaggca ttcaccctgc aggtgctcgg tagcggcggc
     3061 cccatctccg acgatctgcg cgcctcctct agcgaggtgg tctggtggaa gggcaaatcg
     3121 cgcatcctga tcgatgccgg tggcggcgtc tatctgcgct tcggccaggc gggcgccaag
     3181 ctcgaagagg tcgacttcat cggcatcacc cactttcaca ccgaccatgt gaccgacctg
     3241 cctgcgctgc tcaagggggc ctacttcttc aagcgcagcg atcccctcga tctggcgggg
     3301 ccgcaggccg gctcggcctt cccgagcatg agcggctact ttgacgccct gttcaacccg
     3361 agtaaggggg cctatgccta cctcggcggc ttcaaggatg gcaccgatgg tctcttcccc
     3421 atcaatgtgc acgatgtgcc ctaccagaca ccccagcccc atcaggtcta tcagcaggat
     3481 ggcctgacca tcacggcgct tggcatcccc cacggggacg tgccctgtct ggcctatcgc
     3541 atcgaaagcg ccgaggggac catcgtcatc tcggcggatc agaacggcag caacccggcc
     3601 tttgtgccgt ttgccaaggg ggccgacatc ctggtgatgc cgctcgccat ccacgagggc
     3661 gctgatcccg tatccgcttc gctccatgcc aagccctcgg tggtcgccag gattgccgcc
     3721 gaagtgaacc ccaagctgct ggtgctgaac cactggatgg gggtcggtct caatcacaag
     3781 aaggaggcga tggccatcgt caagcagcgg ttccacggcc aggtggtggc cgcccgcgat
     3841 ctctccagtt accccgtttc atccgtcaag gagtccagcc atgagtaacg cacacagcaa
     3901 caagagctcc cgcaaactga gcctctccat cgccatgacc ggcctgatcg cgctgacccc
     3961 cgggcttgcg ctggcggcca ccccgagcga ggcgccggtg aaggcggcgc cgagcgaaca
     4021 gcacggcggc aagtgtgcgg ccggcaagtg cggcaccgag aagcgcttcg agaagcaggc
     4081 cctcgacagc gatccgcagg gccggctggt gcgcgcccgc gatggcaagt gtggtctggc
     4141 ggagcagggg atcaacggcg agacccagcg ccaggagagc aagatgacgg agggggtatg
     4201 cggccaataa gcgccagcag ccgtggcgtg gggctgcgcc aggagcatct ggcccagctc
     4261 tgtgcggtgc ctgcccgccc cggcatcgat tttctcgagc tggcgccgga gaactggatg
     4321 gccattggcg gcgccaggcg ggagcaactg cagcagatcg ccgcgcgcta tccgctggtg
     4381 gcccacgggc tcagcctctc cctcggcgat tgccagccgc tcaatatgac cctgctcggc
     4441 cagatccgcg cctttctcga cgagtttggc attgagatct acagcgagca cctgagcttt
     4501 tcccgcgatg cccggggcta tctctatgag ctgctgccgg tgccgcgcca gtgggagaac
     4561 ctcccctatc tggcggaacg gatccggcag gtacaggatg cgctggcccg cccgttggtg
     4621 ctggagaaca tctcctacta ccacggctat gagcacgaga tggcggagga ggcgtttctg
     4681 accgagctgg tggcgcgcag cggctgcgag ctgctgctcg acatcaacaa cgtttttgtg
     4741 aacagccgca accacggcta ctgtcccgag cggatgattg ccgggctgcc gggccaggcg
     4801 atccgctact tccatatcgc cggccatctg gaagaggcgg acggcaccct gctggatacc
     4861 catggtcgtc cggtctgcga ggaggtggtg gcgctggccc gttatacggt gcagacccac
     4921 ggcctgcgcc ccctgctgct ggagcgggat catcatctgc cccccttgcc cgtgctggag
     4981 gccgagctgg cccgggtcca tcaggcctgc tgcgaggtga tggcgcatcc tgcgggtcgg
     5041 gaggtgtgtc atgactaggc gagagcaagc ggcatggcct gccgcagcgg tcccgccccg
     5101 gctgtggcag cagaccgagt ggctggccgg ttgcatacgg gagtcggcag tcgagctagc
     5161 cccccactat gtgcgcagtg tgcgggccaa tgtcgaggcg gtgctggaga gtaccttcgc
     5221 gcttaccctg aaccacctga cgccggttga gcgcgatgcg ctggtgaatg gcttcgtcgc
     5281 ccaccatggc gcgatcgagc ccgcctttca ccagattgcc accgagctgg tgcgccatgt
     5341 gcaacttcgc cagggggagg gttggctcaa ctggcccggg ctgcggctgg cgctgctgga
     5401 gtatgagtgg gcctgcctgt gcgtcgagat tgacgaggcg caggtgccgc acccgctcgc
     5461 aggggaagcg gtggagatgg gcagcccgct ctggctcaat cccaccctgc agttgctgac
     5521 gctgcccttt gtgatccagc aggggcgggt ggtggcagcc ggtcaggcgc ctcagctctg
     5581 cgccctgttt cgctgccctg cccatcagct ggtcagccag gcgctgcgcg aattcgatgt
     5641 ggccctgctg cagctgcttg ggcagcagca aggggtcagc gtggccgggt tggccgccca
     5701 ggtgcacccc tatcgcagcg gttttgatct gctggggtgg gcccgccatt ttcaccggct
     5761 cggcctgctg gtcactcaac cgccatccat agaaccccca tccattgaac gtcaggtacc
     5821 ccctttccaa ggagacatcc catgaacaac acccttatcc attggtacga gcgggccgtg
     5881 gcccagtgca agcggctcga ttttctggcc ctgctggcca ttcgcctcta cctcatcccg
     5941 gtcatctatg tgggggccca ctccaaggtg gtggggtttg ccggcacggt cgcctggttt
     6001 ggcgcgccag cctcggaagg ggggctcaac ctgccgttcc cgaccctgct cgcctttctg
     6061 gcggcgggca ccgaggtgct gggctgcatc tgcatcgccc ttggtctctt tacccgggtc
     6121 atggccattc cgaccatctt cctgatgagc gtggcgagcg ccatggtgca ctggaagcac
     6181 ggctgggatg ccatcgccac cggcagcatg gaggcgacat tgcgcctcaa cggctttatc
     6241 gagtggctgg ccgccaactt ccccggtcgt tacaactaca tcaccgagct tggggatccc
     6301 gtgatgctca acaacgggat ggagtttgcc gccacctact tcgtgatgct gctggtactg
     6361 ctggtactgc tggtgtatgg cggcggtcgc tacgtcagcc tcgactactg gctggcacgc
     6421 gccgtgacag gcaagggcgg gccgcaagcg gcataacaaa aacaaaataa acagagcgtg
     6481 aaagcgaaac gagcggcatc agccgctcgt ttctattttg cagagcaaag gcctgcggct
     6541 tcagtactgg gggcaggcct gtgccatccg ggtggcttgc cgctcgctga catgggtgag
     6601 gccgtaggcc agcagcacga tcagcgcgcc gatccagggg gtgtgcatca gacccaggtg
     6661 ttccaccacc aggccgccga ccactgagcc cagcgcgatg ccgacgttga aggcggcgat
     6721 attgaggccg gaggccacat ccaccgccct cggcgtgtgt tgctcggcct gtttcaccac
     6781 cagcacctgc aggcccggca cgttgccaaa ggcaaaggcg ccccacacca gcacggtcag
     6841 taccgccagc accgggtgcg gcgcggtgaa ggtgagcacc agcagcacca tggcgagacc
     6901 ggcaaacagc agcttcagcg ctggcagcgg gcccatcttg tcggccagct tgccgcccca
     6961 gatattgccg acggcgaccg acactccgta caccagcaga atgaggctca ccgcgccggc
     7021 gctaaagccg ctcacttgct gcaagatggg ggcgaggaag gtaaaggcgg tgaaggcgcc
     7081 gccgtaaccg agcgctgtct tggcgtagac cagcagcagc ggctttttgg tcagcaccga
     7141 gagctgctcg cggatggtcg aggccgcccc cttgggcagg ttattgggga tcagcagcag
     7201 gctgcccacc atggcgacca ggcccagcag gctcaccacc agaaaggtgt cgcgccagcc
     7261 gaagacctga ccaatccagg tgccgagcgg gacgccggtc accagggcta tggtgaggcc
     7321 gctgaacatg atggcgatgg cgctggccgc tttctctttg gccacgaggc cggtggcaat
     7381 ggtgctgccc accgagaaga agaccccgtg cgccagcccg gtgaggatgc gggcgacgat
     7441 caggctttcg tagccggggg cttgccaggc gagcaggttg ccggcggtaa agagcgccat
     7501 cagccccacc agcagccact tgcgcggcac cttgccggtc agtgccgtca gcacgggagc
     7561 gccgatggcc acgccaaggg catagaggct gaccaagagg cccgccgagg ggagcgagac
     7621 attcagctgc tcggcgatgg tggggatgag ccccacgatc acaaattcgg tggtgccgat
     7681 cgcaaaggca cttaaggtaa gggcaaacaa cgccagtggc ataacaactc cttggatggt
     7741 gactcccgac gggagaatgg cgccagtatg ccgaggtggt ttgttggcaa aaatgacggc
     7801 gacatcaaat tacttttgcc aaataagcag caatggaaca gtggaaggag gagtggctga
     7861 ggcaacgcgg caagtacaac tggtagcgca cgaggtgggg gcagagacaa cgcgtacggc
     7921 agcaatccgt gcatagcgag ccaggacaac gagaaaagag gaaagaggaa aaagttaaga
     7981 ggaaagattt aagaaacaaa gggttgaggg aaggcgctgg gagatcggca cgggcggctg
     8041 tggtgctgtg ttggagacaa aaaagcggga ggcatgatgc ctcccgctca ggttctcgtc
     8101 gatgttgtcg ggttttcttt gctcccttct ccccttgcgg gagaagggtt ggggatgagg
     8161 ggggcctgat gacccaaaaa gaggagcttg ccctcaccct gaccctctcc cacagggaga
     8221 ggggatagcc cgtggctgca ataggctcgt gcgggttgcc gctatccgcc gccgaagcga
     8281 gagaccatgg ctccactctc gtttaatccc aatctggcgc aaagtccggg tcggcacagc
     8341 gctcgccccg ctccagggtg gcgatggcgg ccagctcgtc ggcagtgagg gtgaccttca
     8401 gcgccgccag gttggcggcc aggttctccc gcctggtgga gctcgggatc accgtcatgc
     8461 cctgggccag cagccaggcc agcgacacct gggccgccga gacgccgtgg cgatggccaa
     8521 tttccatcag cagcggctcg gtgagcacct tgccataggc cagcggcata taggcggtga
     8581 tggcgatgcc gtgatctttg cagaactcaa ctaccttgcg gttttgcagc agcgggtgga
     8641 tctccacctg ctggtgggcg atggcgcccg gccccagaat gtcgatggcc tgtttgagct
     8701 gggccacggt aaagttggag accccgatct cgcgggtcag accccgggcc ttggcctcgg
     8761 ccagctgctc cagatagacc gccataggca cctcatccct gggggagggc cagtggatca
     8821 gcgccagatc cagatagtcg gtgcccagtt tttccaggct cacctccagg ctcgggatca
     8881 ccttgcccgg gccgaactcg ctggtccaca ccttggtggt caggtagata tcctggcggg
     8941 gcacgccgct ctcgcgcatc agctggccca cttcggcctc gttggcgtag atctgggcgg
     9001 tatcgatatg gcggtagcca agctcgagcc cttgcagcag agagtcgcgc aggggttggc
     9061 cggtcaggcg aaaggtacca agacccaggt tgggcatctt catcatttat tcctcaaatg
     9121 ggttgtaaaa atgcgctcgg cggcgcggca catcaggcgt ccagcggttg atagcggcga
     9181 atggtgctgc cggcaaacca gggctcggcc gtggtgacaa attcggtgaa atggggttgg
     9241 ccttgatggg cgctgagggc ggcctcgctc tcccacacct cgtagagcat ccagctgtgg
     9301 ggattgtcca aatcctgatg cagctggtag cgcaggcagc cagcctcctg caaggtggcc
     9361 gcgatcaagg ggtccaaggc ggcgcgaaac tggggggcga attcgggttt ggcttcaagc
     9421 tgggcaatca caatcacggg ggatgacat
//
