LOCUS       NZ_CP032365.1          10270 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP032365.1 Bacillus wiedmannii strain SR52 chromosome, complete
            genome.
ACCESSION   NZ_CP032365
VERSION     NZ_CP032365.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:17:50
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2635133
            Orig. end    :: 2645403
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10270
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[2640133:2640403](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5270
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10270
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10270
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="8"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             1385..2464
                     /gene_functions="transport (smcogs) SMCOG1166:transporter,
                     EamA family (Score: 199; E-value: 1.8e-60)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_2547"
                     /transl_table=11
                     /translation="MNYKKWDFRIICAHAFTILIWGTAFPAIRMGLESYTPEHLTLLRL
                     LIASFILLLFSFIYKLRLPDLKDIPAIFIFGALGFTFYHIALNYGEKTVNAGSASLIVS
                     VTPIVTAIFASVFLNEKMKLNGWIGGVISFIGIAFISFSQGDAIQLNSGGLFILLAAIS
                     ESLFFVFQTSYLKKYDFLPFTIYTILSSTICMLIFLPGVYQEILASPIEVNLSVIYLGL
                     FPTVLPYIALAYIISHSGAAEATSSLYLTPVTACFIAWIWLGEVPTFVSIIGGGITILG
                     VLIAHVSLKKKCKVKSTAIQQYSKVVWLVFARNFIELLIRFLIRGRINIMLILFIYTIL
                     TSNIHIKLYSLIIFSHIHN"
     PFAM_domain     1430..1810
                     /aSDomain="EamA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00892.22"
                     /description="EamA-like transporter family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2547_0206"
                     /evalue="3.10E-28"
                     /label="ctg1_2547"
                     /locus_tag="ctg1_2547"
                     /protein_end="142"
                     /protein_start="15"
                     /score="98.7"
                     /tool="antismash"
                     /translation="FTILIWGTAFPAIRMGLESYTPEHLTLLRLLIASFILLLFSFIYK
                     LRLPDLKDIPAIFIFGALGFTFYHIALNYGEKTVNAGSASLIVSVTPIVTAIFASVFLN
                     EKMKLNGWIGGVISFIGIAFISF"
     PFAM_domain     1838..2236
                     /aSDomain="EamA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00892.22"
                     /description="EamA-like transporter family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2547_0207"
                     /evalue="5.20E-19"
                     /label="ctg1_2547"
                     /locus_tag="ctg1_2547"
                     /protein_end="284"
                     /protein_start="151"
                     /score="68.9"
                     /tool="antismash"
                     /translation="SGGLFILLAAISESLFFVFQTSYLKKYDFLPFTIYTILSSTICML
                     IFLPGVYQEILASPIEVNLSVIYLGLFPTVLPYIALAYIISHSGAAEATSSLYLTPVTA
                     CFIAWIWLGEVPTFVSIIGGGITILGVLI"
     CDS             2500..3423
                     /locus_tag="ctg1_2548"
                     /transl_table=11
                     /translation="LEKVLFFGDPGIDDSFAIMYGLLHPEIEIVGIVTGYGNVEHIHAA
                     HNAAYILQLANRQDIPVISGATKPLTEEITAYYPEIHGPEGLGPIHVPESVLSIPIYNF
                     GSIASILVRYGKDLIIVDVGRSTSLAIAFNLWNDLMLNVKGIYFMGGVFLEVGNVTPLA
                     EANVYGDPIASKIIFQQAKNLFIFPLNVTNKAALTPNVFNYIQANSKNPFHTIMKPMYD
                     YYLSAYQKLNPSIEGPLLHDVVAISGLVNPSFFKFAHRTVNVDTFGDTKGQTFADFRPS
                     SLSEGARIALEIDEQKFIQDFIKIML"
     PFAM_domain     2515..3396
                     /aSDomain="IU_nuc_hydro"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01156.21"
                     /description="Inosine-uridine preferring nucleoside
                     hydrolase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2548_0208"
                     /evalue="8.40E-62"
                     /label="ctg1_2548"
                     /locus_tag="ctg1_2548"
                     /protein_end="299"
                     /protein_start="5"
                     /score="209.6"
                     /tool="antismash"
                     /translation="FFGDPGIDDSFAIMYGLLHPEIEIVGIVTGYGNVEHIHAAHNAAY
                     ILQLANRQDIPVISGATKPLTEEITAYYPEIHGPEGLGPIHVPESVLSIPIYNFGSIAS
                     ILVRYGKDLIIVDVGRSTSLAIAFNLWNDLMLNVKGIYFMGGVFLEVGNVTPLAEANVY
                     GDPIASKIIFQQAKNLFIFPLNVTNKAALTPNVFNYIQANSKNPFHTIMKPMYDYYLSA
                     YQKLNPSIEGPLLHDVVAISGLVNPSFFKFAHRTVNVDTFGDTKGQTFADFRPSSLSEG
                     ARIALEIDEQKFI"
     CDS             3502..3960
                     /locus_tag="ctg1_2549"
                     /transl_table=11
                     /translation="LNVQLKVVTRENWEDALKLQVKKDQRKFVPVVAVSLAKVYIKPDG
                     DNVEYIPFAIYDGNLMVGFIMHAVVKETNDMYWINGFIIDQKQQGNGFGKAALQESISL
                     IKNTCKACKEIRLTVHKDNISAKKLYERYGFQPLGHDYDGEQVYRLFV"
     PFAM_domain     3646..3906
                     /aSDomain="Acetyltransf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00583.27"
                     /description="Acetyltransferase (GNAT) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2549_0209"
                     /evalue="1.20E-11"
                     /label="ctg1_2549"
                     /locus_tag="ctg1_2549"
                     /protein_end="135"
                     /protein_start="48"
                     /score="45.0"
                     /tool="antismash"
                     /translation="EYIPFAIYDGNLMVGFIMHAVVKETNDMYWINGFIIDQKQQGNGF
                     GKAALQESISLIKNTCKACKEIRLTVHKDNISAKKLYERYGF"
     CDS             3991..4329
                     /locus_tag="ctg1_2550"
                     /transl_table=11
                     /translation="MQFSEVKIEVFIPEEYIEILRNEINRIGACKTGKYDHCLSYSSVK
                     GYWRPLDDASPFNGEIGQICEGQECKIEIKCKRDLVKDALKVINEIHPYETPMIYIIPL
                     LNDYFNQI"
     PFAM_domain     4174..4305
                     /aSDomain="CutA1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03091.17"
                     /description="CutA1 divalent ion tolerance protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2550_0210"
                     /evalue="4.90E-07"
                     /label="ctg1_2550"
                     /locus_tag="ctg1_2550"
                     /protein_end="105"
                     /protein_start="61"
                     /score="29.6"
                     /tool="antismash"
                     /translation="GQICEGQECKIEIKCKRDLVKDALKVINEIHPYETPMIYIIPLL"
     CDS             4355..4801
                     /locus_tag="ctg1_2551"
                     /transl_table=11
                     /translation="LKNKFHHIVRAVMLKDNKLLVAEYIGHHYFLPGGHVEIGESAENA
                     LIRELREELGVNCSIKQFLGVIENQWEDREVLHYEINHIFEVDSQELHINLRPKSKESH
                     LAFHWIDYNQEALHTYKIMPAPSVKELLERKLSDELLNCWISNF"
     PFAM_domain     4370..4699
                     /aSDomain="NUDIX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00293.30"
                     /description="NUDIX domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2551_0211"
                     /evalue="1.70E-15"
                     /label="ctg1_2551"
                     /locus_tag="ctg1_2551"
                     /protein_end="115"
                     /protein_start="5"
                     /score="57.3"
                     /tool="antismash"
                     /translation="HHIVRAVMLKDNKLLVAEYIGHHYFLPGGHVEIGESAENALIREL
                     REELGVNCSIKQFLGVIENQWEDREVLHYEINHIFEVDSQELHINLRPKSKESHLAFHW
                     IDYNQE"
     aSDomain        5001..5261
                     /aSDomain="TIGR03601"
                     /aSTool="tigrfam"
                     /description="B_an_ocin: bacteriocin,
                     heterocycloanthracin/sonorensin family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2552_0037"
                     /evalue="1.40E-35"
                     /identifier="TIGR03601"
                     /label="ctg1_2552"
                     /locus_tag="ctg1_2552"
                     /protein_end="87"
                     /protein_start="0"
                     /score="119.8"
                     /tool="antismash"
                     /translation="MNQFQQELQSLNLNDYQSGNVVYWDQLQQNQYPYYYIQDDARRCG
                     GCGGCGGRCGGCGGRCGGCAGRCGGCVGCAGCFGCFNCWNWW"
     CDS             5001..5270
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03601"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2552"
                     /sec_met_domain="TIGR03601 (E-value: 4.7e-47, bitscore:
                     156.7, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQFQQELQSLNLNDYQSGNVVYWDQLQQNQYPYYYIQDDARRCG
                     GCGGCGGRCGGCGGRCGGCAGRCGGCVGCAGCFGCFNCWNWWII"
     CDS             5372..5956
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053:beta-lactamase (Score: 59; E-value: 7.7e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2553"
                     /transl_table=11
                     /translation="LYTYDKLISWVENIKENNHSSATALCIIKDNKIVLEHYSGHHSNI
                     STSKKITASSQFNVASARKSYLGLMVAYALYEGKINSIDDEAIKYFNDFDPVLLGKTTI
                     RHLVTHSHGLGETNDGTIFREFEPGQAWAYRDINVRMITRLIYQLYNKSFPELLKKRVF
                     DLANFKETGWRIQEHEKLVKVVDNPNEDAIS"
     PFAM_domain     5402..5902
                     /aSDomain="Beta-lactamase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00144.26"
                     /description="Beta-lactamase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2553_0212"
                     /evalue="6.10E-23"
                     /label="ctg1_2553"
                     /locus_tag="ctg1_2553"
                     /protein_end="177"
                     /protein_start="10"
                     /score="81.7"
                     /tool="antismash"
                     /translation="VENIKENNHSSATALCIIKDNKIVLEHYSGHHSNISTSKKITASS
                     QFNVASARKSYLGLMVAYALYEGKINSIDDEAIKYFNDFDPVLLGKTTIRHLVTHSHGL
                     GETNDGTIFREFEPGQAWAYRDINVRMITRLIYQLYNKSFPELLKKRVFDLANFKETGW
                     RIQE"
     CDS             6047..6388
                     /locus_tag="ctg1_2554"
                     /transl_table=11
                     /translation="VINGKQIVPKEVIKIATSLQSPTFTNNELPQNGLFWFVQNEPALS
                     SELGERVPKGSYQILGITGPTLLVIPECNVVVAKMYNKRYNYGGDNYLYYLREFSNLVA
                     DTFRNGNRA"
     CDS             6420..6563
                     /locus_tag="ctg1_2555"
                     /transl_table=11
                     /translation="VKDKMNKNKKQNIKDVNTEQNAIYSDPKDAANMQTVPQPKDFDEI
                     EY"
     CDS             6848..8056
                     /gene_functions="transport (smcogs) SMCOG1137:Major
                     facilitator superfamily MFS 1 (Score: 424.1; E-value:
                     7.1e-129)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_2556"
                     /transl_table=11
                     /translation="MKQTSINPLLIVLGTIIVQIGLGTIYTWSLFNQPLVSKFGWNLNS
                     VAITFSITSFSLSFSTLFAGKLQQKLGLRKLIATAGIVLGLGLILSSQVSSLPLLYLLA
                     GVVVGYADGTAYITSLSNLIKWFPNRKGLISGISVSAYGMGSLIFRYINGSLIDSLGVS
                     QAFLYWGIIVLLLVLTGSFFLREAIVSNAVTETLHNDYTPREMMRTKQVYLLFFMLFTS
                     CMGGLYLIGMVKDIGVQLVGLSAATAANAVAMIAIFNTVGRIVLGTLSDKIGRMKIVSA
                     TFVIIGLSVFTLSFIPLNYGIYFACVASVAFCFGGNITIFPAIVGDFFGLKNHSTNYGI
                     VYQGFGFGALAGSFIGALLGGFQPTFIIIGVLSVISFIISILIRPPKAEKKKEIKHLHR
                     KIA"
     PFAM_domain     6905..7798
                     /aSDomain="MFS_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07690.18"
                     /description="Major Facilitator Superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2556_0213"
                     /evalue="9.40E-25"
                     /label="ctg1_2556"
                     /locus_tag="ctg1_2556"
                     /protein_end="317"
                     /protein_start="19"
                     /score="87.4"
                     /tool="antismash"
                     /translation="IGLGTIYTWSLFNQPLVSKFGWNLNSVAITFSITSFSLSFSTLFA
                     GKLQQKLGLRKLIATAGIVLGLGLILSSQVSSLPLLYLLAGVVVGYADGTAYITSLSNL
                     IKWFPNRKGLISGISVSAYGMGSLIFRYINGSLIDSLGVSQAFLYWGIIVLLLVLTGSF
                     FLREAIVSNAVTETLHNDYTPREMMRTKQVYLLFFMLFTSCMGGLYLIGMVKDIGVQLV
                     GLSAATAANAVAMIAIFNTVGRIVLGTLSDKIGRMKIVSATFVIIGLSVFTLSFIPLNY
                     GIYFACVASVAFCFGGN"
     CDS             8346..8816
                     /locus_tag="ctg1_2557"
                     /transl_table=11
                     /translation="LVTIIISSFMAFATTNIDDIFILLVLFSQVRTGVIKKEGRAVREK
                     AKVKGLYIVIGQYLGFSVIISLSIIGSLSSFFIPVSWIGLLGFVPIYMGAKGLLSLRSY
                     KSNEVIDNISGSLFKVALITLANGSANISIYIPLFASQNLKTNIVTLIIFFL"
     PFAM_domain     8385..8810
                     /aSDomain="Cad"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03596.15"
                     /description="Cadmium resistance transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2557_0214"
                     /evalue="4.70E-16"
                     /label="ctg1_2557"
                     /locus_tag="ctg1_2557"
                     /protein_end="155"
                     /protein_start="13"
                     /score="59.3"
                     /tool="antismash"
                     /translation="TTNIDDIFILLVLFSQVRTGVIKKEGRAVREKAKVKGLYIVIGQY
                     LGFSVIISLSIIGSLSSFFIPVSWIGLLGFVPIYMGAKGLLSLRSYKSNEVIDNISGSL
                     FKVALITLANGSANISIYIPLFASQNLKTNIVTLIIFF"
     CDS             9336..9629
                     /locus_tag="ctg1_2558"
                     /transl_table=11
                     /translation="VKNEKEDIVGGITAITFWHHVHVDFLWVSEEHRHEGYGSRLIKLI
                     EEFAIETDCGLINLDTFSFQAPNFYKKHGYKVIGVSEDHPKGHNRYYLEKRL"
     PFAM_domain     9345..9560
                     /aSDomain="Acetyltransf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00583.27"
                     /description="Acetyltransferase (GNAT) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2558_0215"
                     /evalue="5.20E-12"
                     /label="ctg1_2558"
                     /locus_tag="ctg1_2558"
                     /protein_end="75"
                     /protein_start="3"
                     /score="46.1"
                     /tool="antismash"
                     /translation="EKEDIVGGITAITFWHHVHVDFLWVSEEHRHEGYGSRLIKLIEEF
                     AIETDCGLINLDTFSFQAPNFYKKHGY"
ORIGIN
        1 ccatataaat aatccaccac taggaatatc ccacgatgca atatctgcac agtacttatt
       61 taaagctcgt atcatgattt gtcttcgttc ttttagtttg attcttacgt ttgcaacatg
      121 ttcttcataa aaacctttat ttatccattc agcagcaact ctttgagata aagagctcga
      181 tccatagtct gtttgcattt ttatatctga caatctatca ataactggtt cgggtccaat
      241 gatccatcca attctaagtc ctgggctaag tgttttagaa agactaccaa catataatac
      301 atgtccgtgt ttatctatcg actttaaagg agctggaggt ggttcatcaa tccataactc
      361 tcggtaaata tcatcttcaa ttataggtaa ctgttccttt tcacatattt ttattatttc
      421 ttttcttcgc tctttagaca ttaatatccc tgttgggttt tgaaaactag ggatagaata
      481 taaaatgttt ttcttttgac tatatttaat acgttttaat aattcgttag gtaaaatacc
      541 gtgatgatcc atacatatac cagagagatt tatatttgct gattgaaata catgaagtga
      601 atataagtaa gaaggttgtt caagtaaaac ggttgattct ctatgcaaaa gaccaattga
      661 tattaattgg agtgcttgta atgcaccaga gacgattaat atagaactgg ctgatgtatg
      721 tattccgaat gattttacgt atttactaat tgcttcacgt aacggcaaaa aacctttttg
      781 ttcttcgtat ccaaaataat ctatttcgtc acttacgctt ttcataatgg actgcatagt
      841 ttctagcggg aaaagttgag gcgcaagttc acctttacta agatggataa gttttttatt
      901 tgcttctgct tcattgattt ctcttaccat taacttgcta ggtttgtgaa taccagcttt
      961 tacatattca ctccaatcag gcgggggatt cgtcgctaat aatgaccatg tattatttgt
     1021 tacaattgtt cctgctccaa ttttcccttg aatcaatcca tctgccataa gttcatctag
     1081 cgcagttatt acagtacttc gatttacatg aaataatttg gctaactgcc gttgactagg
     1141 aatcttactt ccaataggcc attctccatt ttcaattttt tctttcatat agtctactat
     1201 ctgccgatac ttaggcagtt ttttattagt tgtcataaaa aaactccctc gttcacttta
     1261 taaatgccaa gtggttggtt tttacgataa ataactggtt gaagacattg taacaactat
     1321 taaatatgat gaaaagaaat aattggtaat tataaagtgg ttggtttgaa gggggagaaa
     1381 aaacatgaat tataaaaaat gggactttcg gattatttgt gctcatgctt ttacgatttt
     1441 aatatggggg actgcctttc cagcaattcg tatggggctc gaatcttata cacctgagca
     1501 ccttacttta ctacgtttat taatcgcttc atttattctt ctgttgtttt cctttatata
     1561 caagttacga ctgccagatt taaaggatat cccagcaatt tttatatttg gtgctttagg
     1621 atttactttt tatcacattg cattaaacta cggcgaaaaa acagtaaatg ctggatctgc
     1681 aagtttaatt gtttcagtca cacctatagt aacggctatt tttgcatctg tttttttgaa
     1741 tgaaaaaatg aaattaaatg gttggatcgg tggtgtaatt agttttatag gaattgcttt
     1801 catatcattt agtcaaggag atgctattca attgaatagt ggaggattat ttattttatt
     1861 agcagcgatt tcagaaagct tatttttcgt tttccaaact tcttacttga aaaagtatga
     1921 cttcttgcca tttaccatat atacaatctt gtctagtact atatgtatgc ttattttttt
     1981 accaggagtt tatcaagaaa tactggcatc tccaattgaa gtgaatttga gcgttatata
     2041 tttaggttta tttccaacag tactcccata tatcgcattg gcatatatca tatctcattc
     2101 tggtgctgct gaggcaacaa gttctctata tttaactcca gtaactgcat gttttattgc
     2161 ttggatatgg ttaggtgaag tgcccacatt tgtttcgata attggcgggg gaattactat
     2221 acttggggtt ttaattgcac atgtatcatt aaaaaagaaa tgcaaagtga agagtactgc
     2281 aatacagcaa tacagcaagg tagtttggtt agtatttgca agaaatttca tagaactgtt
     2341 aattagattt cttattagag gaaggattaa cataatgtta atccttttta tttatacaat
     2401 tcttactagt aatattcata taaaattgta tagtttaatt atattttcac atatacataa
     2461 ttaacatcat ctattttcct tatgaaaggg cgggatttct tggaaaaagt attatttttc
     2521 ggagacccag gtattgatga ctcgttcgcc attatgtatg gtttattgca tcccgaaatt
     2581 gaaattgtcg gtattgtaac cggatatgga aatgttgaac atatacatgc tgcgcataat
     2641 gcagcgtata ttttacagtt agcaaataga caagacattc ctgtaattag cggggcaaca
     2701 aaaccactta cagaagaaat tacagcatat tatcctgaaa ttcatggacc agaaggatta
     2761 ggtcctattc atgtgccgga aagtgtattg tctatcccaa tatacaattt tggtagtatt
     2821 gcttcgattc ttgtaaggta cggaaaggat ttaataattg tcgatgtagg cagatctact
     2881 tcgttagcga ttgcttttaa tttatggaat gatttaatgc tgaatgtaaa aggaatctat
     2941 ttcatgggtg gtgtcttttt agaagtaggt aacgttacgc cattagcaga ggcaaatgtg
     3001 tatggagatc ctatagcaag taaaattatt tttcagcaag caaagaattt atttatattc
     3061 cctttgaatg taacaaataa agctgcgtta actccaaatg tatttaacta tatccaagct
     3121 aattcaaaga atccatttca tacgataatg aaaccaatgt atgattacta tttatctgca
     3181 taccaaaaac ttaatccatc tatcgaaggg cctttgctac atgatgtggt tgctataagt
     3241 ggattagtta acccaagttt ttttaaattt gcgcatcgta cagtgaatgt agatacattc
     3301 ggagatacga aaggacaaac atttgctgat tttcgcccta gctctttatc tgaaggagcc
     3361 cgtatagctt tagagataga tgaacaaaaa ttcattcaag actttataaa aatcatgtta
     3421 taagttgttg tcgaaaaagg aagttatttc actgtgtaga atataaaaac atatattctc
     3481 tgtataaagg agcttacaat attgaatgtc cagttaaagg ttgttacgag agaaaattgg
     3541 gaagatgcat taaagttaca agttaaaaaa gatcaaagaa aatttgtccc ggttgtagca
     3601 gtttcactag ctaaagtgta tataaaacca gatggtgaca atgtagagta cataccattt
     3661 gcgatatacg acggcaatct aatggttggt tttattatgc atgctgttgt aaaagaaaca
     3721 aatgatatgt attggataaa tggatttatt attgatcaaa agcagcaagg taatggtttt
     3781 ggaaaagcgg cactacaaga aagtatttcc ttaataaaaa atacatgtaa ggcgtgtaaa
     3841 gaaattagat taacagtaca taaagataat atctctgcaa agaaactata tgaacgttac
     3901 ggttttcaac cattgggaca tgattatgat ggcgagcaag tatatcgttt attcgtttaa
     3961 ccattatgaa gtaaaggtgt gaaatgaaag atgcaatttt cagaagtgaa aatcgaagtg
     4021 tttattcccg aagaatacat tgaaatatta cggaatgaaa taaatagaat tggagcttgt
     4081 aaaacgggga aatatgatca ttgtctttcc tatagttccg tgaaaggata ctggagacca
     4141 ttagacgatg catcaccttt taatggggaa ataggtcaaa tatgcgaagg gcaagaatgt
     4201 aaaattgaaa taaagtgtaa aagggacctt gtaaaggatg cacttaaagt tattaacgaa
     4261 attcacccgt atgaaacacc tatgatttat attatccctt tattaaatga ctattttaat
     4321 caaatataaa gtgaatgact gggaggatta acaattgaaa aataaattcc atcatattgt
     4381 acgagctgtt atgttaaagg ataataaatt gttagtggct gaatatattg gccatcatta
     4441 ttttttgccg ggtggtcatg ttgaaattgg cgaatcagct gagaatgcat taattagaga
     4501 actacgagaa gaactcggag taaactgtag tataaaacaa tttttaggag tcatagaaaa
     4561 ccaatgggaa gaccgagaag ttcttcatta tgaaatcaat cacatttttg aagtagattc
     4621 gcaagagtta catattaatt taagaccaaa atctaaagaa tctcatttag cgtttcactg
     4681 gatagattat aatcaagaag ctttacatac gtataaaatc atgccagcgc cttcagttaa
     4741 agagttactg gaaagaaaat taagcgatga actactaaac tgttggatta gtaattttta
     4801 aacacctcta ttaataataa atacgtccac cgaaagaaga ttaagaaaat aggctaaaaa
     4861 acaaggtaca tcacctagtg taagttcata ttttgttgat gtacgcattt agtcgatagc
     4921 cttatttcta ctttgtttgc aaaaatatat tacttttcat atttggacgg aatttatatt
     4981 tataaatgga gggtttcgta atgaatcagt ttcaacaaga actacaatca ttaaacctta
     5041 atgattatca atctggtaat gttgtgtatt gggatcaact gcaacaaaat caatatccat
     5101 actattacat tcaagatgac gcgcgtcgtt gcggcggatg cggaggttgt ggtggacgct
     5161 gtggcggatg tggcggtaga tgcggtggtt gtgcaggtcg ttgcggcgga tgtgtaggct
     5221 gtgctggatg tttcggttgc tttaattgct ggaactggtg gatcatttaa gtataaaaca
     5281 tcaaagctat tttgcttgaa agaaaggtgt gaatactatt ttgcactttt ctttcaagct
     5341 gtaattttta tgcgtattaa gggggattta tttgtataca tacgataagt taatttcttg
     5401 ggtagaaaat ataaaagaaa ataatcatag ttctgcaaca gcactttgta ttataaaaga
     5461 taacaaaatc gtactagagc attatagtgg ccatcattca aatatatcta caagtaaaaa
     5521 aataacagca tcttcacaat tcaacgttgc ttctgcgaga aaaagttatt taggattaat
     5581 ggtagcatat gcgctttacg aggggaaaat aaactctatt gatgacgagg cgataaagta
     5641 ctttaatgat ttcgaccctg tattacttgg taaaacaacg ataagacatt tagtaaccca
     5701 ttcgcacggt ttaggagaaa cgaatgacgg gacaattttt cgtgaatttg aacctggaca
     5761 agcatgggcg tatagagata ttaatgtcag aatgataaca cgtcttattt atcagctata
     5821 taacaaaagt tttcctgaat tgttaaagaa gcgtgtattt gatctagcta acttcaaaga
     5881 aacaggttgg agaattcaag aacatgaaaa attagttaaa gttgttgata atccaaatga
     5941 agacgcgatt agttaaattg gtacggtaga tgatggtact gaaaaaaatc tatttgtctc
     6001 agctagagaa tttgcatagt ggggcaatct tcatttaaat caaggtgtga taaacggaaa
     6061 acaaattgtt ccaaaagaag ttataaaaat tgctacgagt ttgcaaagtc caacatttac
     6121 aaacaatgaa ctaccacaaa acgggttgtt ttggtttgtt caaaatgaac ctgcgctttc
     6181 aagtgaactt ggtgaacgag tgccgaaagg gtcgtatcaa atattaggaa ttacaggacc
     6241 gactctttta gtaatacctg aatgtaatgt agttgttgcg aaaatgtata ataaaagata
     6301 taactacggc ggtgataatt atttatatta tttacgtgaa tttagcaatt tagtcgctga
     6361 tacatttcgt aacggtaata gggcataatt actcctataa tgaaaaggag tgagagaaag
     6421 tgaaagataa aatgaataaa aacaaaaagc aaaatataaa agatgtaaat acagaacaaa
     6481 atgctattta tagtgatcct aaagatgctg ctaatatgca aacggtaccg cagccgaaag
     6541 attttgatga aattgaatat taatttttca ttcatcggac tatatgatga atgaaaaata
     6601 catcttaagt cccatcacat aacaaaaatc ttttggtatc ctatatacat aagcatttga
     6661 aaatgtctta tcttaacaaa gctttcttta agtaaatcta atataacctg cgaaaagaca
     6721 cttcattatg aagtgttttt ttgtgtatat gaacttaatt tccatttttc acacagtatc
     6781 ttgcatttta tgatggttat actaactgtg aaaattcatg tcaagataaa aaaaggggac
     6841 agttagtatg aaacaaactt ctataaatcc gttactaatt gttctaggta caattattgt
     6901 tcaaattggc cttggaacaa tttatacatg gagtttattt aatcaacccc ttgttagtaa
     6961 gtttggatgg aacctcaatt ccgtagcgat aactttctcc ataacaagtt tttcattatc
     7021 attctcaacc ttatttgcag gaaagttgca gcaaaaatta ggacttcgta aactcatcgc
     7081 tactgcaggg attgttctgg gactcggttt aatacttagt tcacaagttt cttccttacc
     7141 attactatat ttattagctg gtgtcgttgt tggttatgca gatggaactg cttatattac
     7201 atcactatct aatttaatta aatggtttcc aaatcgaaaa ggacttattt ctggcatatc
     7261 tgtttcggca tatggaatgg gcagcttaat ctttagatat ataaacggaa gtcttatcga
     7321 tagtcttggt gtatcacaag catttctata ttggggtatc atcgttttac ttttagtatt
     7381 aaccggatcg ttcttcttac gtgaagcaat agtgagtaat gctgtaactg agacattaca
     7441 caatgattat acgcctcgtg aaatgatgcg aacgaaacaa gtatatcttt tattttttat
     7501 gctattcaca tcgtgtatgg gcggtctata tttaatcggt atggtaaaag atattggggt
     7561 acagctcgtt ggacttagtg cagcaactgc cgctaacgcc gttgcaatga ttgcaatttt
     7621 taatacggta ggtagaattg ttcttggaac gttatcagat aaaattggcc gaatgaaaat
     7681 tgtctctgcg acgtttgtta ttattggatt gtcagtcttt actttaagtt ttatcccact
     7741 aaattacggc atttatttcg cttgtgtagc aagtgtcgcc ttttgcttcg gcggtaatat
     7801 cactatattc ccagctattg tcggtgattt cttcggcttg aaaaatcata gtacaaatta
     7861 cggaattgtt taccaaggtt tcggatttgg tgcgcttgca ggatcattca tcggagcact
     7921 acttggtgga tttcaaccga cctttattat aatcggtgtt ttaagcgtta tttccttcat
     7981 tatttcgata ttaattcgtc caccaaaagc agagaagaaa aaggaaataa aacatttaca
     8041 tcggaaaata gcttaatttt aaaaagagtc ctcataaagg actcttttta tattacaaaa
     8101 catttgattt tcccttttta gtcattgtgt aggaagtata gagttactta attcaaagtg
     8161 aaatgatttg aaaagtaata aagtaattta tttcttaacg aaccaagtag cagattagta
     8221 aaatattcat attgttttat aaaggaatca aaatgttgtt ataaaactac agtaaaccag
     8281 ctttgctatt aggcatacaa ttcatttaaa taccattatt ttattataaa ggtagttggc
     8341 ttatattggt tacaatcata atttcttctt ttatggcatt cgctacaacg aatattgatg
     8401 acatttttat actccttgtt ttattttcac aagtaaggac aggagtaatt aaaaaagaag
     8461 gtagagccgt ccgcgaaaaa gctaaggtaa aaggacttta tatagttatt ggacaatatt
     8521 tggggtttag tgtaattatt tctctaagca tcattggttc tttaagctct tttttcattc
     8581 ccgtttcgtg gatcgggtta ttaggattcg tgccaattta tatgggggct aaaggactat
     8641 tgtcacttcg ttcttataaa agtaatgaag tcattgataa catttctggt tcattattta
     8701 aagtagcttt gattacatta gctaatggat ctgccaatat ttcaatttat ataccactgt
     8761 tcgctagtca aaatcttaaa acgaatattg ttacattaat tatctttttt ctatgatagc
     8821 aatatggtgt tttattagct acacattgat aagagcacct attctagcta aagcacttga
     8881 gaaaacctgc catattatcg ttccaattat tctaattggt ttaggaatat tcattctttt
     8941 tcgcagtgat acaattcaat tattctacta aggtgttgaa cttacggaag ttttaattaa
     9001 aaaagaatcg aacaacgtaa atattttcga taattacatt cctttagatt aattcgattc
     9061 tatacagcgt ataaaagtct tattacagat gaaatgtagt agggtttttc tttattttag
     9121 tgaaatgaaa cagtgcccta tgactattaa gttagacagg atattacgat tattaaattg
     9181 aatagatacc ataaaaggag tgtgctattt aaaatgaaaa tagtaaaaca atgggtccag
     9241 gaagatagtg attacataag agaaaagtaa ttgaatataa ccaaaaacat atttcagatg
     9301 aagataaaaa gccttcagaa aaaattagtt ttatagtgaa aaatgaaaag gaagacatag
     9361 taggcggaat aactgcaatt acattttggc accacgtgca tgttgatttc ctatgggttt
     9421 ctgaagaaca tagacacgaa ggctacggaa gcaggttaat aaaacttatt gaagaatttg
     9481 caattgaaac agattgtggg ctaatcaatt tagatacttt tagctttcag gcacctaatt
     9541 tttataaaaa gcatggatat aaagtgattg gagtaagtga agaccaccct aaagggcaca
     9601 atcgatacta tttagaaaaa aggttataaa gtatatagaa tctaaaaatg aatgaattat
     9661 agcaaaaaaa agagcgtacg ttaaatgacc actttcaaaa tacgctcttt tttatatagt
     9721 aatgaaggat tatcgattat taactttgct aagagcggat aaatgaaata ctcaattaac
     9781 ttttttatat tttaaaacga ttaaatggta gaatgtaata aagacagaaa attcctgtta
     9841 ttagaggtga acttagatga aaaaagtaaa tgttacatat gcaattttat acgataaaga
     9901 aaatgaaaag atcttaatgg tcaaaaacaa agggaagaat ggttcttatt acacgctacc
     9961 aggtggcgca gttaaattgg gagaaacgtt agaagaggca gtaattcggg aagtgaaaga
    10021 agaaaccggg ttacatataa ctgtaaacgg tatttgttac atcagcgaag cttttttcga
    10081 agagagaggt catcatgcaa ttttctttaa ttttttaggt gaaataattg gcggagagac
    10141 aaatatttca aggccaaaag aaattgaaga gattacttgg atggaattac atagagcagc
    10201 accatattta cgtataccag aacatttact aaatagatta caaaggaaag aaacagtacc
    10261 ttactttttt
//
