LOCUS       NZ_CP032365.1          25239 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP032365.1 Bacillus wiedmannii strain SR52 chromosome, complete
            genome.
ACCESSION   NZ_CP032365
VERSION     NZ_CP032365.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:17:50
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2493149
            Orig. end    :: 2518388
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25239
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[2503149:2508388]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15239
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..25239
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..25239
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="6"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             1111..1320
                     /locus_tag="ctg1_2400"
                     /transl_table=11
                     /translation="VLSGHAHGGQVRLPFIGGLVAPNQGVLPTYTAGLYEKQNTSMVVS
                     RGLGNSIIPQRIFNRPELVVVQLN"
     CDS             1528..1779
                     /locus_tag="ctg1_2401"
                     /transl_table=11
                     /translation="MHKEYEIEEYTAIEEQIHYYCKCLLVSHPDQIIKYLEKRLEKYAE
                     TLQYAHLYPDTVILPLQQLVIEYSLDVARIRKYMNLKT"
     CDS             1958..2683
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 198.5; E-value:
                     2.2e-60)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_2402"
                     /transl_table=11
                     /translation="VQQPAIILRTVSKSFGKKEVLHNLSLQVEKAEIFGLVGPSGSGKT
                     TLIKLIAGINEATKGEVLVYNTNMPNLNEMKRIGYMAQADALYEELSAYENADFIATMY
                     GLKGKHKKERIEEVFDLVQLSQHIRQQVQHFSGGMKKRLSLAIALLHEPEILILDEPTV
                     GIDPLLRKTIWEKFYDLKKKGTTIIVTTHIMDEAEFCERLGLIREGKLVATGTPEELKK
                     RVSSGRIEDVFLLEEVALL"
     PFAM_domain     2018..2443
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2402_0171"
                     /evalue="5.20E-31"
                     /label="ctg1_2402"
                     /locus_tag="ctg1_2402"
                     /protein_end="162"
                     /protein_start="20"
                     /score="108.1"
                     /tool="antismash"
                     /translation="LHNLSLQVEKAEIFGLVGPSGSGKTTLIKLIAGINEATKGEVLVY
                     NTNMPNLNEMKRIGYMAQADALYEELSAYENADFIATMYGLKGKHKKERIEEVFDLVQL
                     SQHIRQQVQHFSGGMKKRLSLAIALLHEPEILILDEPT"
     CDS             2680..3699
                     /gene_functions="transport (smcogs) SMCOG1065:ABC-2 type
                     transporter (Score: 73; E-value: 3.5e-22)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_2403"
                     /transl_table=11
                     /translation="MRVTGVIIRIIRQFFRDKRSLAMMFGAPMLLLWLLSLVFTQKDYV
                     PHIAVVDVPAPIVKTMKTQEASIYEYGKEKAISELELQKVDAVIYLENRKMNLLLEGSD
                     SSKNRAVLQVLQKSTEKNEVSVMKPEVNYLHGSKDFTMFDGLGPVLIGFFTFFFVFILS
                     GVSFVRERLSGTLERLLSTPVRRWEIVVGYIIGFGIFAFIQSIIIVNFSVYILDLYVAG
                     SIWLTLLITCLLSLTALTLGTFLSAYANNEFQMIQFIPLVIVPQIFFSGLFPIESMNKW
                     LQMLGKLFPLTYGADAMRQVMIRNQGFTEIALDLTVLLLFSLLFAIGNVFALKKHRKI"
     PFAM_domain     3106..3585
                     /aSDomain="ABC2_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01061.26"
                     /description="ABC-2 type transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2403_0172"
                     /evalue="6.90E-35"
                     /label="ctg1_2403"
                     /locus_tag="ctg1_2403"
                     /protein_end="302"
                     /protein_start="142"
                     /score="120.5"
                     /tool="antismash"
                     /translation="FDGLGPVLIGFFTFFFVFILSGVSFVRERLSGTLERLLSTPVRRW
                     EIVVGYIIGFGIFAFIQSIIIVNFSVYILDLYVAGSIWLTLLITCLLSLTALTLGTFLS
                     AYANNEFQMIQFIPLVIVPQIFFSGLFPIESMNKWLQMLGKLFPLTYGADAMRQVM"
     CDS             3739..4377
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 99.1; E-value: 7.2e-30)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2404"
                     /transl_table=11
                     /translation="LDELIAATNTDKRNERQMRILEAAVDMFGEKGYASTSTSEIAKRA
                     GVAEGTIFRYYKTKKDLLLAVVMPTLTKFAAPFFVQAFAKEIFKSQYESYEGLLRVVIH
                     NRFEFAKKHFPMIKILIQEVPFQPELKNEIQHLVETELLSHFKKLIVKFQEEGEIIEMP
                     PSSVLRLTLSAVLGLLLTRFLLLPEEKWDDEVEIENTIQFILYGLTPRI"
     PFAM_domain     3796..3936
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00440.25"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2404_0173"
                     /evalue="1.60E-18"
                     /label="ctg1_2404"
                     /locus_tag="ctg1_2404"
                     /protein_end="66"
                     /protein_start="19"
                     /score="66.3"
                     /tool="antismash"
                     /translation="ILEAAVDMFGEKGYASTSTSEIAKRAGVAEGTIFRYYKTKKDLLL
                     AV"
     CDS             complement(4577..4900)
                     /locus_tag="ctg1_2405"
                     /transl_table=11
                     /translation="MKKKLSSILSVLALSIMFLGTSAQAEYDGNHMNRVNNTDMSTRVN
                     DNNLNRVNDNNLNRVNNDVRTRNVNTTNDLNNNRDRNNNWAWLGLLGLAGLLGLRRRDK
                     ETR"
     CDS             complement(5073..5588)
                     /locus_tag="ctg1_2406"
                     /transl_table=11
                     /translation="MGVLSGNPQNEPMHYGEVFAIWSYLAGAQGAIAGYQVLVNHTGDE
                     DLKKFLENLIENDIQSEVEELKNLLKSNGVALPPAPPERPVASIETIPPGARINDAEIA
                     AKVSMDLAAGLVACSQAMGQSLREDVGMMFGQFHMKKAQAGATLLRLNKKKGWIIPPPL
                     HVLQSDQA"
     PFAM_domain     complement(5094..5582)
                     /aSDomain="DUF3231"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11553.10"
                     /description="Protein of unknown function (DUF3231)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2406_0174"
                     /evalue="7.70E-43"
                     /label="ctg1_2406"
                     /locus_tag="ctg1_2406"
                     /protein_end="165"
                     /protein_start="2"
                     /score="146.1"
                     /tool="antismash"
                     /translation="VLSGNPQNEPMHYGEVFAIWSYLAGAQGAIAGYQVLVNHTGDEDL
                     KKFLENLIENDIQSEVEELKNLLKSNGVALPPAPPERPVASIETIPPGARINDAEIAAK
                     VSMDLAAGLVACSQAMGQSLREDVGMMFGQFHMKKAQAGATLLRLNKKKGWIIPPPLHV
                     "
     CDS             6054..7022
                     /locus_tag="ctg1_2407"
                     /transl_table=11
                     /translation="MRQFAKPTIVVSKCLEFDACRYNAEMIPDVTIRNLQPFVTFIPVC
                     PEVEIGLGTPRETIRIVEENGVNRLVQPSTREDVTEKMKQFSNDFLQTISDVDGFILKN
                     RSPSCGTRDVKIYSGFEKAPVKGKGSGLFGGAVIKKFSHLPIEEEGRLSNFIIREHFFT
                     RLFTIAHYKMIKHTKNIKELVSFQSDYKYLFMAYNQVKQKELGRIIANQKNETIEVVFE
                     NYEKTLYELFMRTPRYTSNVNVCEHIFGYFKTKLKKQEKDHFLDLIQKYIEKKVPLSSL
                     LTILKSWAIRFDDKYLLRQTYFEPYPEALVEISDSGKGRDY"
     PFAM_domain     6078..6500
                     /aSDomain="2-thiour_desulf"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04463.14"
                     /description="2-thiouracil desulfurase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2407_0175"
                     /evalue="2.80E-35"
                     /label="ctg1_2407"
                     /locus_tag="ctg1_2407"
                     /protein_end="149"
                     /protein_start="8"
                     /score="121.4"
                     /tool="antismash"
                     /translation="IVVSKCLEFDACRYNAEMIPDVTIRNLQPFVTFIPVCPEVEIGLG
                     TPRETIRIVEENGVNRLVQPSTREDVTEKMKQFSNDFLQTISDVDGFILKNRSPSCGTR
                     DVKIYSGFEKAPVKGKGSGLFGGAVIKKFSHLPIEEE"
     PFAM_domain     6624..6974
                     /aSDomain="DUF1722"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08349.13"
                     /description="Protein of unknown function (DUF1722)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2407_0176"
                     /evalue="1.70E-41"
                     /label="ctg1_2407"
                     /locus_tag="ctg1_2407"
                     /protein_end="307"
                     /protein_start="190"
                     /score="141.3"
                     /tool="antismash"
                     /translation="KYLFMAYNQVKQKELGRIIANQKNETIEVVFENYEKTLYELFMRT
                     PRYTSNVNVCEHIFGYFKTKLKKQEKDHFLDLIQKYIEKKVPLSSLLTILKSWAIRFDD
                     KYLLRQTYFEPYP"
     CDS             7239..8384
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 452; E-value:
                     2.7e-137)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2408"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.8e-39, bitscore:
                     133.2, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 5.6e-26, bitscore:
                     88.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 7.5e-57, bitscore:
                     190.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFTLTREKQMIKEMVRDFAEKEIAPKAVYYDKTAEFPYETFQKM
                     GELGLLGIPFPEEYGGSGGDTVSYALAVEEIGRACGGTGLSYAATISLGASPIYYFGTE
                     EQKQKYLVPMASGKTLGAFGLTEPNAGSDAGGTQTKAVLDGDEYVISGEKCWITNAEYA
                     NTIIVTAINGVEDNGRKRISAFIVPTTSEGLTISSPYDKMGVRASNTCEIVLDGVRVPK
                     ENILGDVNKGFKQFLYTLDGGRISIAALAVGIAQSAFERALQYAKERQQFGKSISNFQA
                     IQFKLADMATEVELARNLVHKAAWLKDNDKPFGKEAAMAKLFASEAASRIANQAVQIHG
                     GYGYMREYEVERHIRDAKLLEIGEGTSEIQRLVIARHLGCR"
     PFAM_domain     7254..7592
                     /aSDomain="Acyl-CoA_dh_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02771.18"
                     /description="Acyl-CoA dehydrogenase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2408_0177"
                     /evalue="2.00E-39"
                     /label="ctg1_2408"
                     /locus_tag="ctg1_2408"
                     /protein_end="118"
                     /protein_start="5"
                     /score="134.8"
                     /tool="antismash"
                     /translation="TREKQMIKEMVRDFAEKEIAPKAVYYDKTAEFPYETFQKMGELGL
                     LGIPFPEEYGGSGGDTVSYALAVEEIGRACGGTGLSYAATISLGASPIYYFGTEEQKQK
                     YLVPMASGK"
     PFAM_domain     7602..7892
                     /aSDomain="Acyl-CoA_dh_M"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02770.21"
                     /description="Acyl-CoA dehydrogenase, middle domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2408_0178"
                     /evalue="3.40E-26"
                     /label="ctg1_2408"
                     /locus_tag="ctg1_2408"
                     /protein_end="218"
                     /protein_start="121"
                     /score="91.4"
                     /tool="antismash"
                     /translation="AFGLTEPNAGSDAGGTQTKAVLDGDEYVISGEKCWITNAEYANTI
                     IVTAINGVEDNGRKRISAFIVPTTSEGLTISSPYDKMGVRASNTCEIVLDGV"
     PFAM_domain     7926..8372
                     /aSDomain="Acyl-CoA_dh_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00441.26"
                     /description="Acyl-CoA dehydrogenase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2408_0179"
                     /evalue="2.60E-56"
                     /label="ctg1_2408"
                     /locus_tag="ctg1_2408"
                     /protein_end="378"
                     /protein_start="229"
                     /score="190.1"
                     /tool="antismash"
                     /translation="NKGFKQFLYTLDGGRISIAALAVGIAQSAFERALQYAKERQQFGK
                     SISNFQAIQFKLADMATEVELARNLVHKAAWLKDNDKPFGKEAAMAKLFASEAASRIAN
                     QAVQIHGGYGYMREYEVERHIRDAKLLEIGEGTSEIQRLVIARHL"
     PFAM_domain     8400..8729
                     /aSDomain="Biotin_carb_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00289.24"
                     /description="Biotin carboxylase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2409_0180"
                     /evalue="2.40E-45"
                     /label="ctg1_2409"
                     /locus_tag="ctg1_2409"
                     /protein_end="110"
                     /protein_start="0"
                     /score="153.7"
                     /tool="antismash"
                     /translation="MFQKILIANRGEIAVRIIKTCQKLGIRTVAIYSEADENALHVKMA
                     NEAYLVGGSRVQESYLNLEKIIEIAKKTNAEAIHPGYGLLSENPSFPVRCREEGIVFIG
                     PSEEII"
     CDS             8400..9737
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090:acetyl-CoA carboxylase biotin carboxylase (Score:
                     643.6; E-value: 6.7e-195)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2409"
                     /sec_met_domain="RimK (E-value: 3e-06, bitscore: 25.3,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 4.8e-09, bitscore:
                     34.3, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQKILIANRGEIAVRIIKTCQKLGIRTVAIYSEADENALHVKMA
                     NEAYLVGGSRVQESYLNLEKIIEIAKKTNAEAIHPGYGLLSENPSFPVRCREEGIVFIG
                     PSEEIITKMGSKIESRIAMQAADVPVVPGITTNIETAEEAIEIAKQIGYPLMLKASAGG
                     GGIGMQLMETEQTLTKAFESNKTRAQNFFGNGEMYLERYIADAHHIEIQLLADTHGNTV
                     YLWERECSVQRRNQKVIEEAPSPFLDEGTRKAMGEVAVQAAKALGYTNAGTVEFLVDDQ
                     KNFYFLEMNTRLQVEHPVTEEITGLDLVEQQLLIAYGEKLSFTQDDVKRSGHAIEARIY
                     AEDPKTFFPSPGKITDLTLPKNVRIDHFLENQVTITPFYDPMIAKVIAHGETREEAISK
                     LHDALEELKVEGIKTNTPMLIQVLEDDVFKSGIYTTGFVTKQLVKK"
     PFAM_domain     8745..9365
                     /aSDomain="CPSase_L_D2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02786.19"
                     /description="Carbamoyl-phosphate synthase L chain, ATP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2409_0181"
                     /evalue="3.80E-75"
                     /label="ctg1_2409"
                     /locus_tag="ctg1_2409"
                     /protein_end="322"
                     /protein_start="115"
                     /score="252.1"
                     /tool="antismash"
                     /translation="KIESRIAMQAADVPVVPGITTNIETAEEAIEIAKQIGYPLMLKAS
                     AGGGGIGMQLMETEQTLTKAFESNKTRAQNFFGNGEMYLERYIADAHHIEIQLLADTHG
                     NTVYLWERECSVQRRNQKVIEEAPSPFLDEGTRKAMGEVAVQAAKALGYTNAGTVEFLV
                     DDQKNFYFLEMNTRLQVEHPVTEEITGLDLVEQQLLIAYGEKLS"
     PFAM_domain     9405..9716
                     /aSDomain="Biotin_carb_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02785.21"
                     /description="Biotin carboxylase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2409_0182"
                     /evalue="8.60E-35"
                     /label="ctg1_2409"
                     /locus_tag="ctg1_2409"
                     /protein_end="439"
                     /protein_start="335"
                     /score="119.2"
                     /tool="antismash"
                     /translation="EARIYAEDPKTFFPSPGKITDLTLPKNVRIDHFLENQVTITPFYD
                     PMIAKVIAHGETREEAISKLHDALEELKVEGIKTNTPMLIQVLEDDVFKSGIYTTGFVT
                     "
     CDS             9764..9979
                     /locus_tag="ctg1_2410"
                     /transl_table=11
                     /translation="MMTKVYASMAGNVWKIVVGVGDTVEEEQDVVILESMKMEIPIVSE
                     EAGTVMKINVQEGDFVNEGDVLLEIE"
     PFAM_domain     9785..9973
                     /aSDomain="Biotin_lipoyl"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00364.24"
                     /description="Biotin-requiring enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2410_0183"
                     /evalue="2.30E-17"
                     /label="ctg1_2410"
                     /locus_tag="ctg1_2410"
                     /protein_end="70"
                     /protein_start="7"
                     /score="62.7"
                     /tool="antismash"
                     /translation="SMAGNVWKIVVGVGDTVEEEQDVVILESMKMEIPIVSEEAGTVMK
                     INVQEGDFVNEGDVLLEI"
     CDS             10001..10912
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 220; E-value:
                     1.1e-66)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2411"
                     /sec_met_domain="HMGL-like (E-value: 2.9e-47, bitscore:
                     159.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKLPNFAVIKEVGPRDGLQNEKKIVGTKDKVKWIQLLTEAGLSYV
                     EVSSFVHPKWVPALADANDVFSELKRDPNVTYAALVPNQNGLERAFLQNVDEVNVFLSA
                     SESHNKSNINKSIKEALVVIEDITKQALFEGKKVRGYVSTVFGCPYEGDISTAAVDELC
                     NQLFSYGIYEVSLGDTIGVANPLQVERVLEHLLKKYDASQFAMHFHNTYGMALANVVKS
                     LEYGITTFDSSCGGLGGCPYAPGASGNVATDDLVHMLHKLGVQTNIDEEKLLKASHFIQ
                     SKLNIQLPSHVYRALQHKTISR"
     PFAM_domain     10025..10840
                     /aSDomain="HMGL-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00682.21"
                     /description="HMGL-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2411_0184"
                     /evalue="1.10E-47"
                     /label="ctg1_2411"
                     /locus_tag="ctg1_2411"
                     /protein_end="280"
                     /protein_start="8"
                     /score="162.9"
                     /tool="antismash"
                     /translation="IKEVGPRDGLQNEKKIVGTKDKVKWIQLLTEAGLSYVEVSSFVHP
                     KWVPALADANDVFSELKRDPNVTYAALVPNQNGLERAFLQNVDEVNVFLSASESHNKSN
                     INKSIKEALVVIEDITKQALFEGKKVRGYVSTVFGCPYEGDISTAAVDELCNQLFSYGI
                     YEVSLGDTIGVANPLQVERVLEHLLKKYDASQFAMHFHNTYGMALANVVKSLEYGITTF
                     DSSCGGLGGCPYAPGASGNVATDDLVHMLHKLGVQTNIDEEKLLKASHFI"
     CDS             10917..11705
                     /NRPS_PKS="Domain: ECH (14-254). E-value: 6.8e-75. Score:
                     243.3. Matches aSDomain: nrpspksdomains_ctg1_2412_ECH.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 256.8; E-value:
                     2.7e-78)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2412"
                     /transl_table=11
                     /translation="MLQLQNISVDYVTPHVVKISLNRERQANSLSLALLEELQNILTQI
                     SEESNTRVVILTGAGEKAFCAGADLKERAGMNEEQVRHAVSMIRTTMEMVEQLPQPVIA
                     AINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKEL
                     IYTGRRISAQEAKEYGLVEFVVPAHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQV
                     DLHTGLQMEKQAYEGVIHTKDRLEGLQAFKEKRTPMYKGE"
     aSDomain        10959..11678
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2412_ECH.1"
                     /evalue="6.80E-75"
                     /label="ctg1_2412_ECH.1"
                     /locus_tag="ctg1_2412"
                     /protein_end="254"
                     /protein_start="14"
                     /score="243.3"
                     /tool="antismash"
                     /translation="HVVKISLNRERQANSLSLALLEELQNILTQISEESNTRVVILTGA
                     GEKAFCAGADLKERAGMNEEQVRHAVSMIRTTMEMVEQLPQPVIAAINGIALGGGTELS
                     LACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKE
                     YGLVEFVVPAHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYE
                     GVIHTKDRLEGLQAFKEK"
     PFAM_domain     10962..11699
                     /aSDomain="ECH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00378.22"
                     /description="Enoyl-CoA hydratase/isomerase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2412_0185"
                     /evalue="5.90E-71"
                     /label="ctg1_2412"
                     /locus_tag="ctg1_2412"
                     /protein_end="261"
                     /protein_start="15"
                     /score="238.8"
                     /tool="antismash"
                     /translation="VVKISLNRERQANSLSLALLEELQNILTQISEESNTRVVILTGAG
                     EKAFCAGADLKERAGMNEEQVRHAVSMIRTTMEMVEQLPQPVIAAINGIALGGGTELSL
                     ACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEY
                     GLVEFVVPAHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEG
                     VIHTKDRLEGLQAFKEKRTPMYKG"
     CDS             11708..13249
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase,
                     (Score: 519.5; E-value: 1.8e-157)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2413"
                     /transl_table=11
                     /translation="MLDQKQQSNTFEERVETIKQGGAPKYHEQNKAKGKLFVRDRLALL
                     FDNGEYVEDALFANCEQTGLPADGVITATGKIHGRMACVMANDSTVKAGSWGARTVEKI
                     LRIQETAEKLRVPLFYLVDSAGARITDQVEMFPGRRGAGRIFYNQVKLSGKVPQVCLLF
                     GPSAAGGAYIPAFCDVVMMVEGNASMYLGSPRMAEMVIGEKVTLEEMGGARMHCSVSGC
                     GDVLCKTEEDAITQARQYISYFPNNYLEKTPLVTPQEPKQFDKTLEQIIPENQNAPFNM
                     KDLINRVIDEGSFYEVKKLFAQELITGLARIDGKPVGIIANQPRMKGGVLFHDSADKAA
                     KFINLCDAYHIPLLFLADVPGFMIGTKVERAGIIRHGAKMISAMSEATVPKISIVVRKA
                     YGAGLYAMAGPAFEPDCCLALPTASIAVMGPEAAVNAVYANKIAALPEEERDSFIAEKR
                     EEYKKDIDIYHLASEMVIDGIVHPNNLREELKGRFEMYMSKYQVFTDRKHPVYPV"
     PFAM_domain     11795..13237
                     /aSDomain="Carboxyl_trans"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01039.24"
                     /description="Carboxyl transferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2413_0186"
                     /evalue="4.50E-158"
                     /label="ctg1_2413"
                     /locus_tag="ctg1_2413"
                     /protein_end="510"
                     /protein_start="29"
                     /score="527.0"
                     /tool="antismash"
                     /translation="NKAKGKLFVRDRLALLFDNGEYVEDALFANCEQTGLPADGVITAT
                     GKIHGRMACVMANDSTVKAGSWGARTVEKILRIQETAEKLRVPLFYLVDSAGARITDQV
                     EMFPGRRGAGRIFYNQVKLSGKVPQVCLLFGPSAAGGAYIPAFCDVVMMVEGNASMYLG
                     SPRMAEMVIGEKVTLEEMGGARMHCSVSGCGDVLCKTEEDAITQARQYISYFPNNYLEK
                     TPLVTPQEPKQFDKTLEQIIPENQNAPFNMKDLINRVIDEGSFYEVKKLFAQELITGLA
                     RIDGKPVGIIANQPRMKGGVLFHDSADKAAKFINLCDAYHIPLLFLADVPGFMIGTKVE
                     RAGIIRHGAKMISAMSEATVPKISIVVRKAYGAGLYAMAGPAFEPDCCLALPTASIAVM
                     GPEAAVNAVYANKIAALPEEERDSFIAEKREEYKKDIDIYHLASEMVIDGIVHPNNLRE
                     ELKGRFEMYMSKYQVFTDRKHPV"
     CDS             13299..15239
                     /NRPS_PKS="Domain: AMP-binding (97-521). E-value: 5e-82.
                     Score: 267.5. Matches aSDomain:
                     nrpspksdomains_ctg1_2414_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     258.3; E-value: 1.9e-78)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2414"
                     /sec_met_domain="AMP-binding (E-value: 4.5e-88, bitscore:
                     293.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKQAVWFPTEEYKEKTRLYGWLKSLGYEDYETFYNKSIEETDWFW
                     GEAEKAVGYQWMKPYTEVLDLENGTPFAQWYNGGTCNVVESVLSRWLADDETRTQPALQ
                     YEGENGTSKSFTYEELDNWVSRVANGLKHAGIEKGDRVTIYMPMIPETVVSMLAVMKIG
                     AIISPIFSGFASDAVMTRVQAAGSKMIITADGFSRRGKIVSLKDEVDKACEHCPTVEKV
                     VIVRHAGNDFTPHHYDFSWSTLEKEKPFTHAEEMHSDDPLMLIYTSGTTGKPKGTVHTH
                     AGFPLKAAFDAGFGMNIKQGDRVLWVTDMGWMMGPFLLFGSLINGATMVMYEGVPDFPE
                     ADRLWETVDKYEITHLGISPTLIRALMAKGDEYVNKHSLKSLEVFASTGEPWNPDPWMW
                     LFETVGKSNVPICNYSGGTEISGGIFGNVLIKPIAPISFNASLPGMAAVVLDDQGNPIR
                     DEVGELCLEKPWVGMTKSFWEDDERYVNTYWSRFENKWVHGDWVIYDGEQYIITGRSDD
                     TLNIAGKRIGPAEYESILVKHNDVIEAAAIGVPDDVKGEVCHCFVVLRDNVTFTGELKK
                     ELMSLVNSHIGKALCPKDIHVVEDLPKTRNSKVMRRVIKAAYLGKELGDLSSLVNPEVV
                     PFIQGLQSSKL"
     PFAM_domain     13386..13553
                     /aSDomain="ACAS_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16177.7"
                     /description="Acetyl-coenzyme A synthetase N-terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2414_0187"
                     /evalue="1.30E-12"
                     /label="ctg1_2414"
                     /locus_tag="ctg1_2414"
                     /protein_end="85"
                     /protein_start="29"
                     /score="47.5"
                     /tool="antismash"
                     /translation="YETFYNKSIEETDWFWGEAEKAVGYQWMKPYTEVLDLENGTPFAQ
                     WYNGGTCNVVE"
     PFAM_domain     13587..14861
                     /aSDomain="AMP-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00501.30"
                     /description="AMP-binding enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2414_0188"
                     /evalue="1.20E-75"
                     /label="ctg1_2414"
                     /locus_tag="ctg1_2414"
                     /protein_end="521"
                     /protein_start="96"
                     /score="254.8"
                     /tool="antismash"
                     /translation="TRTQPALQYEGENGTSKSFTYEELDNWVSRVANGLKHAGIEKGDR
                     VTIYMPMIPETVVSMLAVMKIGAIISPIFSGFASDAVMTRVQAAGSKMIITADGFSRRG
                     KIVSLKDEVDKACEHCPTVEKVVIVRHAGNDFTPHHYDFSWSTLEKEKPFTHAEEMHSD
                     DPLMLIYTSGTTGKPKGTVHTHAGFPLKAAFDAGFGMNIKQGDRVLWVTDMGWMMGPFL
                     LFGSLINGATMVMYEGVPDFPEADRLWETVDKYEITHLGISPTLIRALMAKGDEYVNKH
                     SLKSLEVFASTGEPWNPDPWMWLFETVGKSNVPICNYSGGTEISGGIFGNVLIKPIAPI
                     SFNASLPGMAAVVLDDQGNPIRDEVGELCLEKPWVGMTKSFWEDDERYVNTYWSRFENK
                     WVHGDWVIYDGEQYIITGRSDDTLNI"
     aSDomain        13590..14861
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2414_AMP-binding.1"
                     /evalue="5.00E-82"
                     /label="ctg1_2414_AMP-binding.1"
                     /locus_tag="ctg1_2414"
                     /protein_end="521"
                     /protein_start="97"
                     /score="267.5"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="RTQPALQYEGENGTSKSFTYEELDNWVSRVANGLKHAGIEKGDRV
                     TIYMPMIPETVVSMLAVMKIGAIISPIFSGFASDAVMTRVQAAGSKMIITADGFSRRGK
                     IVSLKDEVDKACEHCPTVEKVVIVRHAGNDFTPHHYDFSWSTLEKEKPFTHAEEMHSDD
                     PLMLIYTSGTTGKPKGTVHTHAGFPLKAAFDAGFGMNIKQGDRVLWVTDMGWMMGPFLL
                     FGSLINGATMVMYEGVPDFPEADRLWETVDKYEITHLGISPTLIRALMAKGDEYVNKHS
                     LKSLEVFASTGEPWNPDPWMWLFETVGKSNVPICNYSGGTEISGGIFGNVLIKPIAPIS
                     FNASLPGMAAVVLDDQGNPIRDEVGELCLEKPWVGMTKSFWEDDERYVNTYWSRFENKW
                     VHGDWVIYDGEQYIITGRSDDTLNI"
     CDS_motif       14085..14141
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_2414_0001"
                     /evalue="7.60E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg1_2414"
                     /protein_end="281"
                     /protein_start="262"
                     /score="24.7"
                     /tool="antismash"
                     /translation="MLIYTSGTTGKPKGTVHTH"
     CDS_motif       14832..14894
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_2414_0002"
                     /evalue="7.80E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg1_2414"
                     /protein_end="532"
                     /protein_start="511"
                     /score="12.3"
                     /tool="antismash"
                     /translation="TGRSDDTLNIAGKRIGPAEYE"
     PFAM_domain     14886..15122
                     /aSDomain="AMP-binding_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13193.8"
                     /description="AMP-binding enzyme C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2414_0189"
                     /evalue="1.40E-21"
                     /label="ctg1_2414"
                     /locus_tag="ctg1_2414"
                     /protein_end="608"
                     /protein_start="529"
                     /score="77.4"
                     /tool="antismash"
                     /translation="EYESILVKHNDVIEAAAIGVPDDVKGEVCHCFVVLRDNVTFTGEL
                     KKELMSLVNSHIGKALCPKDIHVVEDLPKTRNSK"
     CDS             complement(15685..15882)
                     /locus_tag="ctg1_2415"
                     /transl_table=11
                     /translation="MDKKNLLSQQLDYVSSDALNTPSKAQEQMQETSQEAHDSNKKDST
                     QALHGDDLPISDVYRTTNKQ"
     CDS             16199..16414
                     /locus_tag="ctg1_2416"
                     /transl_table=11
                     /translation="MVIVTLAIVPGESRSEAVTVTVPGPLAARNTAVKLPEAFVMTARG
                     TMKAREGLLNEKLTTTPGVGLPFTNT"
     CDS             16460..16735
                     /locus_tag="ctg1_2417"
                     /transl_table=11
                     /translation="VVSLEVKVIDAGPAGRLNPVGPVGPVGPVGPVEPVEPVGPVGPVG
                     PVEPVEPVGPVGPVDPVGPVDPVGPVEPVGPVEPVAPVEPVGPVGN"
     CDS             complement(17007..17375)
                     /locus_tag="ctg1_2418"
                     /transl_table=11
                     /translation="MGNIPNVSSQQSNPNIPSQQVNPNTQQGNNKKTRRRIITILALIL
                     PIIFVLQYSLNNQQEMIKEKQITLNTEQQKLSSLKKDGHSLKNDVKALTDSEEEILKFA
                     RKLYGFSKPNETIFKITE"
     PFAM_domain     complement(17013..17237)
                     /aSDomain="DivIC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04977.17"
                     /description="Septum formation initiator"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2418_0190"
                     /evalue="3.20E-15"
                     /label="ctg1_2418"
                     /locus_tag="ctg1_2418"
                     /protein_end="121"
                     /protein_start="46"
                     /score="55.8"
                     /tool="antismash"
                     /translation="IIFVLQYSLNNQQEMIKEKQITLNTEQQKLSSLKKDGHSLKNDVK
                     ALTDSEEEILKFARKLYGFSKPNETIFKIT"
     CDS             17704..17874
                     /locus_tag="ctg1_2419"
                     /transl_table=11
                     /translation="LYQGDYFIKEGTILEVSEKANKSLYWLRCMLAPSYEKVCGNSTKR
                     LWLIRIDDDEE"
     CDS             18041..18421
                     /locus_tag="ctg1_2420"
                     /transl_table=11
                     /translation="METSTFLGLFWGWVTVIVSGILFVRPSVLRELKKLVVEDRGFGIM
                     YGFLSIFLGLGSVILHNVWVFNWQGFLTFIAWLALLKGIYIIAYPEPSKKTDFEVRVLS
                     TRIVLAIIGALALWMLIVIYIK"
     CDS             complement(19039..19455)
                     /locus_tag="ctg1_2421"
                     /transl_table=11
                     /translation="VNKQAIFLLKHRIIVILLKGGIKECPGKMIAGVLRKSIVVMTGGN
                     LKNSTIVMMIGGNLKKNTIVMMIGGNLKNSIAMMIGVLNEISVAVNVSLFVVIVKENIG
                     NILNVNLKERIYLLGPVNTRIYKKLTKYSQLFIY"
     CDS             20080..20436
                     /locus_tag="ctg1_2422"
                     /transl_table=11
                     /translation="LGSRFNNCRKKCTCKHDDCWDVFEECKKEQHEKCDSSCVQGIRDE
                     LKKLINKTVRINTEGRTYIGTVSSVTCDVVKLAAIPGSVAAIISLCKIEAILPPATTVA
                     DEFDFNGVDVANKE"
     CDS             20562..21077
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111:GCN5-related N-acetyltransferase (Score: 73.1;
                     E-value: 4.5e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2423"
                     /transl_table=11
                     /translation="VIKLKQFTRTDFKQLINWIDCEEFLIQWSGNVFTYPLHEQQLEKY
                     IESKNTLAFKVIDEETRKVIGHISLGQIDNINKSARIGKVLVGDTKMRGRSIGKHMMKA
                     VLQIAFEELKLHRVTLGVYDFNTSAISCYEKVGFVKEGLLRESKKVGETYWNLWEMSML
                     EYEWSDKK"
     PFAM_domain     20652..20975
                     /aSDomain="Acetyltransf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00583.27"
                     /description="Acetyltransferase (GNAT) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2423_0191"
                     /evalue="1.70E-13"
                     /label="ctg1_2423"
                     /locus_tag="ctg1_2423"
                     /protein_end="138"
                     /protein_start="30"
                     /score="51.0"
                     /tool="antismash"
                     /translation="NVFTYPLHEQQLEKYIESKNTLAFKVIDEETRKVIGHISLGQIDN
                     INKSARIGKVLVGDTKMRGRSIGKHMMKAVLQIAFEELKLHRVTLGVYDFNTSAISCYE
                     KVGF"
     CDS             21129..21689
                     /locus_tag="ctg1_2424"
                     /transl_table=11
                     /translation="MNKNTKVISVAAVSGGGKTTVTESLTHKLMNSKALYFDSYNFDNC
                     PADICKWIDDGANYDEWVLTPLIKDIQHLLQNSYLDYIIVDYPFAYLNSEMRQFIDVTI
                     FIDTPLDIAMARRILRDFKEDTMSEIQNDLKHYITYARKAYLEALHTVKPNSDIVLDGS
                     LSVDEIINQILESLNRREVIVNG"
     CDS             21676..22410
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2425"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.6e-08, bitscore:
                     31.8, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 2.5e-09, bitscore: 35.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LSMVKCIEEYVQVDDFKMYSKVFQGKQLQPVIIMEAGYGDYSKTW
                     DHIAEELTEYGTVLSYDRAGLGKSGKSFKRRISSEMVKDLRSCLEQLQLKPPYIFVGHS
                     FGGINARLFATFYPEDMLGIVLADSTPENYKEDFLPIMSNEFQEAYYKQFVYESSYEEF
                     TFSLSEVDRCCESMNDIPLVVLAAGKKAFYSSDEQMKWLQLQEELLRLSSNNKFVIATQ
                     SGHYIQKDEPYYVIDAVKWIIG"
     PFAM_domain     21763..22056
                     /aSDomain="Hydrolase_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12146.10"
                     /description="Serine aminopeptidase, S33"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2425_0192"
                     /evalue="1.50E-12"
                     /label="ctg1_2425"
                     /locus_tag="ctg1_2425"
                     /protein_end="127"
                     /protein_start="29"
                     /score="47.4"
                     /tool="antismash"
                     /translation="PVIIMEAGYGDYSKTWDHIAEELTEYGTVLSYDRAGLGKSGKSFK
                     RRISSEMVKDLRSCLEQLQLKPPYIFVGHSFGGINARLFATFYPEDMLGIVLA"
     CDS             22424..22882
                     /locus_tag="ctg1_2426"
                     /transl_table=11
                     /translation="MYTLFQYNWQVRDDWFKWCEQLSEEELLRKRVGGVGSILETLFHI
                     VDVEYSWINALQGKEDNEPQFKDYQSIQKVKALSDLYKRELEDFLQLWSSSLECKILKA
                     SWTDKTYTYGEVLRHVIVHEIHHIGQLSIWARELNLQPVSANLIGRGL"
     PFAM_domain     22430..22858
                     /aSDomain="DinB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05163.14"
                     /description="DinB family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2426_0193"
                     /evalue="5.10E-31"
                     /label="ctg1_2426"
                     /locus_tag="ctg1_2426"
                     /protein_end="145"
                     /protein_start="2"
                     /score="107.9"
                     /tool="antismash"
                     /translation="TLFQYNWQVRDDWFKWCEQLSEEELLRKRVGGVGSILETLFHIVD
                     VEYSWINALQGKEDNEPQFKDYQSIQKVKALSDLYKRELEDFLQLWSSSLECKILKASW
                     TDKTYTYGEVLRHVIVHEIHHIGQLSIWARELNLQPVSA"
     CDS             complement(22941..23957)
                     /locus_tag="ctg1_2427"
                     /transl_table=11
                     /translation="MQFLKKFTILFLSFVITALIVLYFYLYVNGPIIQAKSAILIDANS
                     GEVVYKKNEETPIQSATLSKLMTEYITMEQLNEGKIQLDELVKISNEVFRAETSPIQVT
                     SKDKTTVRDLLHALFLTGNNRSALALAEHIAGNEDNFTLLMNEKAKQLKLSQPSPFLNA
                     TGMNNDTNKQSTTTAIDVAKLATQLVKDFPDVLNVTKLTSYQFTFKDSKVFNTNKMIYS
                     LNKNIKLQGVDGLQTSFSTNGNYSFVSTAKRGDTRLISVILDSNEENSTFIETKKLLQY
                     GFDPSSYSALQAFKDAVTSWTVLLQFKNLIIQTLLIFFIITFLMFLHIRQKKSEDFN"
     PFAM_domain     complement(23163..23867)
                     /aSDomain="Peptidase_S11"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00768.22"
                     /description="D-alanyl-D-alanine carboxypeptidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2427_0194"
                     /evalue="8.30E-54"
                     /label="ctg1_2427"
                     /locus_tag="ctg1_2427"
                     /protein_end="265"
                     /protein_start="30"
                     /score="182.6"
                     /tool="antismash"
                     /translation="PIIQAKSAILIDANSGEVVYKKNEETPIQSATLSKLMTEYITMEQ
                     LNEGKIQLDELVKISNEVFRAETSPIQVTSKDKTTVRDLLHALFLTGNNRSALALAEHI
                     AGNEDNFTLLMNEKAKQLKLSQPSPFLNATGMNNDTNKQSTTTAIDVAKLATQLVKDFP
                     DVLNVTKLTSYQFTFKDSKVFNTNKMIYSLNKNIKLQGVDGLQTSFSTNGNYSFVSTAK
                     RGDTRLISVILDS"
ORIGIN
        1 tataggaaga cctgatttat tagaaactgc tgtaggtatg aaaaatactg caaaaatagg
       61 agcgaaacaa ttatttaatt ctatacaaaa aataaaaata ctccctgatt atttgcaaat
      121 atggccatca catggtgcag gaagcgcatg tggaaaagca ttaggagcaa ttccaacttc
      181 tacattaggt tatgaaaaga tgttcaattg ggcatttcag tgtaatgaag aaagtgattt
      241 tgtatcgact ttattgacgg gacagccaga gcctccaaag tatttttcat taatgaagaa
      301 tttaaataag tctggtcctc caaatcgtaa gaagagagat gttattgcta ttaaaacagt
      361 agaaaaactt caagaagtta tgacgagcgt tcagcaaata gttgatataa gggatgtaga
      421 gagttttgct tctggtcaca ttgagaaatc aattaacata ccttataaca attcctttac
      481 aacttggtgt ggatggttac tagattataa aacagaaact ttaatcattc tagatgagga
      541 aaaggttaga gtggaggaag ttattagaga ctttgaatct attgggctag ataatattat
      601 tgcttttgta cctgtaaagg taatacaaag attgaataga ttagaaagtt acaaagaaga
      661 cacatcaatc gaattatatc cgcatataaa aggtggaagt gttaagttaa tcgacgtgcg
      721 tagtaaaaaa gagtgggagg aaggacatct tcatgatgca atacatatcc ctttaggaaa
      781 tctatttaag cagctagatt gtataccaaa agattgccca atagttttac aatgtcgaac
      841 cggattgcgt tccgctatag cagctagtat tttacaaaga gcaggtataa aggaagtagt
      901 gaatttaaag ggaggatttc ttgcatggca aaaagaagag cttccttata aaacatgtaa
      961 tcgcaatgtg tagggaaata aattttatta atttatccga taaggaaaat tgcggattac
     1021 ataggagtat atctatatat aggagcaata gatgatttat tctatagacc tgaatttatt
     1081 cagaattatg ctgatgagca aatagattta gtgttatcag ggcatgctca tggagggcaa
     1141 gttagattgc catttatcgg aggtttagtt gctccaaatc aaggggttct ccctacatat
     1201 acagccggtt tatatgaaaa acaaaatacg tctatggtag taagtagagg actaggtaat
     1261 agtatcattc cgcaaagaat tttcaataga ccagaacttg tagtcgtaca gttaaattga
     1321 actgtacgat tttttgtata gaaaaataag ccatatgtaa tttatacaag ttaacattac
     1381 aattttgtta aaaattttct acgttacata aagtaacaaa atttgacccg taaagtttgt
     1441 tatagtgtaa ataatcaaaa aacttaaaaa ttagtcgagt gaaaagtgtg ataaggaatc
     1501 tgtataaaaa cataaagggg tgtacacatg cataaagaat atgaaattga agagtatacg
     1561 gcgattgagg aacaaataca ttattattgt aaatgcttat tagtaagtca tcctgatcaa
     1621 attataaagt atttagaaaa aaggttagaa aaatatgcag aaacattaca atatgcccat
     1681 ttatatcccg acacagttat attaccgtta cagcaattag ttatcgaata ttctttagat
     1741 gttgctagaa ttaggaaata tatgaattta aaaacgtaaa ataaaatata taatttaaat
     1801 gaaacagagt cgactttaag aaatgatatt ctaatgtcga ctctgtttca ttgtttaaga
     1861 ttgaaaatac atactaatca atgaagtttg acatataatt acgcaagagt aaaataaaag
     1921 tgagtactca ctcattttag aaaaggggga agaatacgtg cagcaacctg ccattatttt
     1981 acggactgta tcaaaaagtt ttggaaaaaa agaagtgtta cacaatcttt cattgcaagt
     2041 tgaaaaagca gagatatttg gtttagttgg gccttcaggt tcagggaaaa cgactcttat
     2101 taaattgatt gcaggtatta atgaggcaac gaaaggtgaa gtgcttgtat acaacacgaa
     2161 catgcctaat ttaaatgaaa tgaaaagaat tggttatatg gctcaggctg atgcattata
     2221 tgaagaacta tcagcatatg aaaatgcaga ttttattgca acgatgtatg gattaaaggg
     2281 aaaacataaa aaagaaagaa tcgaagaggt ttttgacctt gtacaattat cacaacatat
     2341 aagacagcaa gtgcagcatt tttcaggtgg gatgaagaag cgtttatcat tagcgatagc
     2401 actccttcat gaacctgaaa tattaatttt agatgagcca acagtgggga tagatccact
     2461 tcttagaaaa acaatctggg aaaaatttta tgatttgaaa aagaaaggca caactattat
     2521 tgtaacgacg cacattatgg atgaagctga attttgtgaa cgcctaggat taattagaga
     2581 agggaagcta gttgcgactg gaacacctga agaattgaaa aaacgggtat catcaggacg
     2641 gattgaagat gtctttttgt tggaagaggt ggctctatta tgagagttac tggtgtaatc
     2701 attcgtatta ttcgccaatt ttttcgagat aaacgttcgt tagcgatgat gtttggggca
     2761 ccaatgttat tactttggtt attgtctcta gtgtttacac aaaaagacta tgtaccgcat
     2821 atcgctgtag ttgatgtgcc tgctcctatt gtaaaaacaa tgaaaactca agaagcctca
     2881 atttatgaat acggcaaaga gaaagcaatt tcagagttag aactgcaaaa ggtagatgca
     2941 gtaatttatt tagagaatag gaaaatgaat cttttattag aaggaagtga ttcatcaaaa
     3001 aatcgtgctg tacttcaagt tttacaaaag agtacagaaa agaatgaagt atcagttatg
     3061 aagcctgagg taaattactt acatggctct aaagacttta caatgtttga tgggcttggt
     3121 cccgtattga ttggtttctt tacatttttc tttgtattta tattgtctgg agtttccttt
     3181 gttagagaac gtttaagtgg tacattagag aggttattgt ccactccagt gagaagatgg
     3241 gaaatagttg taggatatat tattggtttt ggaatctttg cgtttataca atcaattata
     3301 atcgtgaatt tttcagttta tattttagat ttgtatgtag ctggttccat atggctaacg
     3361 ctacttatta catgcctgct ttctttaacg gcattaactt tagggacgtt tttatcagca
     3421 tacgcaaata atgaatttca aatgatccag ttcataccgc ttgtcattgt gccccaaatt
     3481 ttcttttctg ggttgtttcc aattgaatct atgaataagt ggctacaaat gttagggaaa
     3541 ttatttccgc tcacatatgg agctgacgca atgagacaag tgatgattcg aaatcaagga
     3601 tttacagaga ttgcgttaga tctaactgta ttactacttt tttctctatt atttgcaata
     3661 gggaatgtat ttgcattaaa gaaacatcgg aaaatataat gatgatacaa aggggcatta
     3721 tagatgaaga aggattggtt ggatgaatta attgccgcaa ctaatacgga taaacgaaat
     3781 gaacgtcaaa tgcgtatttt agaggcagct gttgatatgt ttggagaaaa aggatatgca
     3841 tcaacttcta caagtgaaat tgcaaagcgt gctggtgtag cggaaggaac aatcttccgc
     3901 tactataaaa cgaaaaaaga tttattgtta gcagtcgtca tgccgacatt aacaaagttt
     3961 gctgcaccat tttttgtaca agccttcgca aaggaaattt tcaaatcgca gtatgaatcg
     4021 tatgaagggc tgctaagagt tgttattcat aatagatttg aatttgcaaa aaagcatttt
     4081 ccaatgataa aaatattaat tcaagaagtg ccatttcagc cagaattgaa aaacgaaata
     4141 caacatttag tagaaacaga gttactttca cattttaaaa agttgattgt aaagtttcaa
     4201 gaagaagggg aaattattga gatgcctcca tcttctgtat tacgtcttac tttatcagct
     4261 gtattaggtt tactattaac aaggttttta ttattgcctg aagaaaaatg ggatgatgaa
     4321 gtggagattg aaaatacgat tcaatttata ttgtatggat taacgccacg aatctaacta
     4381 taacaacatt ttaggggttt gattttttgt atttaaataa atgtaattta ataggtttaa
     4441 tcataagtaa aaatatgttg atgtgtgaat ttcatatact atttttaagc aaataataaa
     4501 tcgcctttaa aaaggcgatt tatattcatt atacaatttt gataaataag tacttgttta
     4561 ctaaaaatat tttgaattag cgtgtttctt tgtctcttct tctaagacct aataatcctg
     4621 ctagacctaa taaaccgagc caagcccaat tattatttct atcacgatta ttatttaaat
     4681 catttgtcgt atttacattt cgagttctca catcattatt aactctgttc aagttattat
     4741 cattaactct gttcaagtta ttgtcattaa ctcgagttga catatcagtg ttattaactc
     4801 tattcatatg atttccatcg tattcagctt gggcagatgt gcctaaaaac ataatagata
     4861 gtgctaaaac acttaaaata gatgataatt ttttcttcat aaatttcccc tcctttctta
     4921 tgtattaatt tttccattgc ttttgtacat tattcgtatc acagtatcta aatcataaag
     4981 ttaaaattat tagaactatc tttaatctcc attattaaaa gtacaggtaa atacaacgaa
     5041 gcggttaaca aaagttaacc gcttatgcca tgttatgctt gatcagattg aagaacatgt
     5101 aaagggggag gaataatcca gccttttttc ttatttaacc gtagtaaagt agcacctgct
     5161 tgtgcttttt tcatatggaa ttgtccaaac atcattccta cgtcttctcg aagtgattgt
     5221 cccatcgctt ggctacatgc tactagtcca gcagcaagat ccatagaaac tttagctgca
     5281 atttctgcgt cattaatacg agcaccagga gggattgttt caatagatgc aactggacgt
     5341 tctggaggtg ctggtggtaa tgccacaccg tttgatttta acaagttttt tagttcttca
     5401 acttctgatt ggatatcatt ttctataaga ttttctaaaa acttttttaa gtcctcgtct
     5461 ccagtatgat tgacaagaac ttggtaacca gcaattgcac cttgtgcccc tgcaagataa
     5521 ctccaaattg caaagacttc tccgtaatgc attggttcat tttggggatt accacttaat
     5581 actcccattt taatatgcct ccttaaactg aatggatttt ttgaaatatt tcttaccaaa
     5641 gaaaaaatac ttctgaaaat gttccgtaat aaagaaagta ggtttctaaa attcatttgg
     5701 aacaccctaa ctacaagtaa tactttctca gtctataatg tacaaattta aagaatatat
     5761 tctaaataac ttgggattaa aattcatatt aaggcttatt ttaatttaaa tgtaaagagg
     5821 aaaggaaaga atctgtaact atgctagtaa agatggattg tgtttagaca aaaaagtgtt
     5881 aacaagtttg tacaagaact tgttaataca tatacgaaat agatttgaat tgcagttgat
     5941 atagcattaa atttatagtt attataaaaa taatcaatat aaacagactt tgcttaagat
     6001 actaatatca gtacaattta gattgtatgg attgatacca tggaggtaat gaaatgcggc
     6061 aatttgcaaa accaacaatt gttgtaagta aatgtttaga atttgatgcc tgtcgttata
     6121 atgcagagat gataccagat gtaacaatac gaaatttgca gccatttgtt acatttatac
     6181 ctgtttgtcc agaagtcgag atcggattgg ggactcctcg tgaaacgata cgaattgtag
     6241 aagaaaatgg tgtgaatagg cttgtacagc cgtcgacacg agaagatgta actgaaaaaa
     6301 tgaagcaatt ttcaaatgac tttttacaaa cgatatccga tgtggatggt tttattttaa
     6361 agaatcgttc gccaagttgt ggtacgcgcg atgtgaaaat ttattctggt tttgaaaaag
     6421 cgccagtaaa aggaaaggga tctggcttat ttggcggagc agtaataaaa aaattttcgc
     6481 atcttccaat tgaagaagag ggtagattgt cgaattttat tattagagaa catttcttta
     6541 caagactgtt tacaatcgcg cattacaaaa tgattaaaca tactaaaaac ataaaagaac
     6601 tcgtatcatt tcaatcagac tataagtatt tatttatggc atataatcaa gtgaaacaaa
     6661 aagaattagg gcgtattatt gcaaatcaaa aaaatgaaac gattgaagtt gtatttgaaa
     6721 actatgagaa gactttatat gaattattta tgcgcacccc ccgctataca tcgaatgtaa
     6781 atgtatgtga gcatattttt ggatatttta aaacaaagtt gaaaaaacaa gaaaaagatc
     6841 attttttaga tttgatacaa aagtatatag aaaagaaagt cccgcttagt agcttactta
     6901 caattttaaa atcatgggcc attcgatttg acgataagta tttattaaga caaacatatt
     6961 ttgaaccata ccctgaagct ttagtagaaa tttctgattc gggaaaaggt agagattatt
     7021 aaacaataaa ttacataatt cgacacaaaa cttcctatgt tgttgtagaa caatgtagga
     7081 atttttttgt gcattagtac agaatctgtt ttaaaattga gttatgacag aattatagca
     7141 attgtctaac taatattcgt gtcttttaat tcgtaatgtt tgtagtagaa actcgcacgc
     7201 tgtcgaaact caatattcga taaggggtgt gtagcggaat ggaatttact ctaactcgcg
     7261 aaaaacaaat gattaaagaa atggtacgtg actttgctga aaaggaaatc gcaccgaaag
     7321 ctgtgtatta tgacaaaact gcggaatttc catatgaaac atttcaaaaa atgggcgaac
     7381 taggattatt aggtatccca ttccctgaag agtatggagg ttcaggtggc gatactgtat
     7441 cgtacgcgtt agcagttgaa gaaattggtc gtgcttgtgg tgggacagga ttaagttacg
     7501 ctgcaacaat ttcattaggt gcttctccaa tttattattt cggtacagaa gaacaaaaac
     7561 agaaatattt agttccaatg gcgtcaggta aaacattagg tgctttcgga ttaactgagc
     7621 cgaacgctgg atctgatgca ggtggtacac aaacgaaagc tgtattagat ggagacgagt
     7681 atgttattag tggtgaaaag tgttggatta caaatgcaga gtatgcaaat acaattattg
     7741 taaccgctat caacggtgtt gaagataatg gtagaaagcg tatttcggca tttatcgtac
     7801 cgactacaag tgaaggatta acgatttcaa gtccttacga taagatgggt gttcgtgctt
     7861 ctaatacatg tgaaatcgta cttgatggtg tacgtgtacc gaaagaaaat attcttggtg
     7921 atgtaaataa aggatttaaa caattcttat atacacttga tggaggacgt atttcaatcg
     7981 cagcattagc agtaggtatt gcacaatctg catttgaacg tgcgctgcaa tatgcgaaag
     8041 aacgtcaaca atttggaaag tcaatctcta atttccaagc gattcaattt aaattagctg
     8101 atatggcgac tgaagtagaa cttgcacgta atttagtaca taaagcagct tggttaaaag
     8161 ataatgataa acctttcggt aaagaagcgg ctatggcaaa gttatttgca tctgaggctg
     8221 ctagtcgtat tgcaaatcaa gcggtacaaa ttcacggtgg atacggctat atgcgtgaat
     8281 atgaagtgga acgacatatt cgtgatgcaa aactattaga aattggtgaa ggaacttctg
     8341 aaattcaacg tctcgtaatt gcaagacatt taggatgtag ataaaaagga ggaatcacta
     8401 tgtttcaaaa aatattaatt gctaatcgcg gggaaatcgc agttcgtatt ataaaaactt
     8461 gtcaaaaact tggcattcgc actgttgcta tttattctga ggctgatgaa aatgcccttc
     8521 atgtaaaaat ggcaaatgaa gcttacttag taggtggatc gcgtgtccaa gaaagctatt
     8581 taaaccttga aaaaattatt gaaatagcta agaagacaaa tgctgaagca atccatccgg
     8641 gatatggatt attatcagag aatccgtctt ttccggttcg ctgtagagaa gaagggattg
     8701 tatttatagg tccatcagaa gaaatcatta cgaaaatggg aagtaaaatc gaatctcgta
     8761 ttgcaatgca agctgcagat gtcccagtag ttccaggtat tactacaaat attgaaactg
     8821 ctgaagaagc aattgaaatt gcaaaacaaa ttggttatcc attaatgctg aaggcatccg
     8881 caggcggcgg aggcattgga atgcagttga tggaaactga gcaaacgctc accaaagcat
     8941 ttgaaagtaa caaaacaaga gcacaaaact tcttcggtaa cggagaaatg tatttagagc
     9001 gctatattgc agatgcacat catattgaaa ttcagctttt agcagataca catggtaaca
     9061 cagtgtattt atgggagcgt gaatgttccg tgcagcgccg aaatcagaaa gtaattgaag
     9121 aagcaccttc accattttta gatgaaggta cgcgaaaagc gatgggagaa gttgctgtac
     9181 aagctgccaa agctctaggc tatacaaacg caggtacagt tgagtttctt gtagatgatc
     9241 agaagaactt ttatttctta gagatgaata cgagattaca agtagagcat ccagttacag
     9301 aagaaattac tggtttagat cttgtagaac aacaacttct aattgcatat ggtgagaaat
     9361 tatcgtttac acaagatgat gtaaaacgta gtggtcatgc cattgaggcg cgtatttatg
     9421 cagaagatcc gaaaactttc ttcccatcac ctgggaaaat tacagattta acgcttccaa
     9481 aaaatgtacg tattgatcac tttttggaga atcaagtaac gattacacct ttctacgatc
     9541 caatgattgc gaaagttatt gctcatggtg aaactcgtga agaagcaatt tcgaaattac
     9601 atgatgcttt agaagagtta aaagtagaag gcattaaaac gaacacacca atgctaattc
     9661 aagtattgga agacgatgtg ttcaaaagtg gtatttatac aacaggtttt gtaacgaaac
     9721 aacttgttaa aaaataagat ttaccaatat taagggggaa aaaatgatga cgaaagtata
     9781 tgcatcgatg gcaggaaatg tatggaagat tgttgtagga gtaggagata cagtagagga
     9841 agagcaggat gtcgtcattt tggaatctat gaaaatggaa attccaatcg tttcagaaga
     9901 agctggcaca gttatgaaaa ttaatgtgca agaaggcgat tttgtaaatg aaggagatgt
     9961 attactagaa attgaatagg gagatatagg gggaagcgaa ttgaaactac ctaattttgc
    10021 tgtcattaaa gaagtcgggc cacgcgatgg cttacaaaat gaaaaaaaga ttgttggcac
    10081 aaaagataaa gtaaaatgga ttcaactact tacagaggcg ggattatcgt acgttgaagt
    10141 ttcctcattc gttcacccta aatgggtccc tgcattagca gatgcaaatg atgtgttttc
    10201 tgagctaaaa agggatccca atgttacata tgcagcgctt gttccaaatc aaaatggttt
    10261 ggaacgagct tttttgcaaa atgtagatga ggtgaatgtt tttttatcag caagtgaatc
    10321 tcataataaa agtaatatta ataaatcaat taaagaagca ttagttgtaa ttgaagatat
    10381 aacaaaacag gcattattcg aagggaaaaa ggtaagaggc tatgtttcta ctgtatttgg
    10441 atgtccttat gaaggggata taagtaccgc agcagttgac gaattatgta atcaactatt
    10501 ttcatacggc atttatgaag tctcgcttgg tgacacgatc ggtgtagcga atccactaca
    10561 agtagagcga gtattagaac atttattaaa gaaatacgat gcttcgcagt ttgcaatgca
    10621 tttccataat acgtacggta tggctctggc gaatgtagtt aagtctttag aatatggtat
    10681 tacaacattt gatagttctt gtggtggtct tggtggatgt ccatatgcac caggagcatc
    10741 aggcaatgtt gcaaccgatg acttagttca tatgctccat aagttagggg tccaaacgaa
    10801 tattgatgaa gagaagttat tgaaagcgag tcacttcatt caaagtaaat taaatatcca
    10861 attaccgagt catgtgtata gagcgcttca acataaaacg ataagtaggt gagaagatgc
    10921 tacaattaca aaacatttca gttgattatg taacacctca cgttgtaaag atttcattaa
    10981 atcgtgaaag acaagcaaac tcattatctt tagcgttatt agaagagtta caaaatatat
    11041 taactcaaat aagtgaagag tccaatactc gcgtagttat tttaacaggt gctggtgaaa
    11101 aagctttttg tgctggtgct gatttaaaag aacgtgctgg catgaatgaa gaacaagttc
    11161 gccatgctgt tagtatgatt cgtactacta tggagatggt tgaacaatta ccacagccag
    11221 ttattgctgc tataaatgga atcgcccttg gtggcggtac ggaattaagt ttagcttgtg
    11281 attttagaat tgcggctgaa tctgcaagtc tcggtcttac tgaaactaca cttgcaatta
    11341 taccaggagc aggtggtacg cagcgtttgc caagattaat tggtgttggt agagcgaagg
    11401 aattaattta tacaggaaga cgtatttcgg cgcaagaagc aaaagaatat ggtttagtag
    11461 aatttgttgt accagctcat ttacttgaag agaaagcaat tgaaatagca gagaaaattg
    11521 ctagtaatgg tcctattgct gttcgattag caaaagaagc aatttcaaac ggtattcaag
    11581 ttgatttaca taccggatta caaatggaaa aacaagcgta tgaaggtgta atccatacga
    11641 aagatagatt agaaggatta caagcattca aggaaaaacg cacaccaatg tataaggggg
    11701 agtaaatatg ttagaccaaa aacaacaatc gaatacattt gaagaacgag ttgaaacgat
    11761 taaacaaggc ggcgcaccaa aatatcatga acaaaacaaa gcaaagggaa aactattcgt
    11821 tcgagatcgt ttagcgcttt tatttgataa tggtgaatat gtagaagatg cattatttgc
    11881 aaactgtgaa caaactggat tacctgctga tggtgttata acggcaacgg gtaaaataca
    11941 tggtcgtatg gcatgtgtga tggcaaatga ttcaactgta aaagctggat catggggggc
    12001 acgtacagtt gaaaagattt tacgtattca agaaacggca gaaaaattac gtgttccgtt
    12061 attttattta gttgactctg ctggagcgcg tattactgat caagttgaaa tgttcccagg
    12121 gcgccgtggt gcaggaagaa ttttctataa tcaagtgaaa ttatcaggta aagttccgca
    12181 agtatgctta ttatttggac cttctgcagc tggtggcgca tatattccag ccttttgtga
    12241 tgttgttatg atggtggaag gaaatgcatc tatgtattta gggtctcctc gtatggctga
    12301 gatggttatc ggcgagaagg taaccttaga agaaatgggc ggagcacgta tgcattgctc
    12361 tgtatcagga tgcggagatg ttttatgtaa gaccgaagaa gatgcgatta cacaagcaag
    12421 acaatacatt tcatattttc caaacaacta cttagaaaag actccattgg ttacacctca
    12481 agaaccgaaa caattcgata aaacgttaga acaaatcatt ccagaaaatc aaaatgctcc
    12541 tttcaatatg aaagatctca ttaatagagt tattgatgaa ggttctttct atgaagtgaa
    12601 aaaactattt gctcaagaac tcattacagg tttagcacgt attgatggta agccagttgg
    12661 tattattgca aatcaaccgc gtatgaaagg cggcgtatta ttccacgatt cagctgataa
    12721 agcagcgaaa tttattaatt tatgcgatgc gtatcatatt ccattattat tccttgcaga
    12781 tgtacctgga tttatgattg gtacaaaagt agagcgtgct ggtattattc gccacggtgc
    12841 aaaaatgatt tctgcaatga gtgaagcaac tgtaccgaaa atttctatcg ttgttcgtaa
    12901 agcatacggt gctggtttat atgcaatggc aggtccagcc tttgaaccag attgctgctt
    12961 agcattaccg acagcttcta ttgcggtaat gggtccagaa gcagcagtca atgctgtata
    13021 tgcaaataag attgcagctt taccagaaga agagcgtgat agcttcattg ctgaaaaacg
    13081 cgaagagtat aagaaagata ttgatattta ccatttagca tcagagatgg tcattgatgg
    13141 tattgttcat ccaaacaatt tacgagaaga gttaaaagga cgattcgaaa tgtatatgag
    13201 taaatatcaa gtatttacgg atcgtaaaca tcctgtttat ccagtttaaa agccctattt
    13261 agggctttct tgctcaaaaa gtcaaggagg ggaaaacatt gaaacaagca gtttggtttc
    13321 caacagaaga atataaagaa aaaacgcgtt tatatggttg gctgaaatca ttgggctatg
    13381 aagattatga aacgttttat aataaatcta ttgaagaaac agattggttt tggggagaag
    13441 ctgagaaagc ggttggctat caatggatga agccttatac agaagtgcta gatttagaaa
    13501 atggtacgcc gtttgcacag tggtataatg gcggaacatg taacgttgta gaatcagttt
    13561 tatcacgctg gcttgcagat gatgaaacaa gaacgcaacc agcactacag tacgagggag
    13621 aaaatggaac ttcaaaatca tttacatatg aagagcttga caactgggta agtcgcgttg
    13681 caaacggttt gaaacatgcg ggtattgaaa aaggtgaccg tgtaacaatt tatatgccga
    13741 tgattccaga aacagttgtt tcaatgctag ctgttatgaa aatcggagca attatttcac
    13801 caatattctc aggatttgca tctgatgcag tcatgactcg tgtacaagcg gcaggatcaa
    13861 aaatgatcat tactgcagat ggtttttcac gccgcggtaa aattgtttca ttaaaagatg
    13921 aagtagataa agcttgtgag cattgtccaa ctgttgaaaa agttgttatc gttcgtcatg
    13981 caggaaatga ttttacaccg catcattacg atttctcatg gagtacgcta gaaaaagaaa
    14041 aaccatttac acatgctgaa gaaatgcata gtgatgatcc gttaatgctc atttacacat
    14101 caggtacaac tgggaaaccg aaaggaacag tacatacaca tgctggtttc cctttgaaag
    14161 ctgcatttga tgcaggattt ggaatgaata tcaaacaagg tgatcgcgtg ttatgggtaa
    14221 ctgatatggg atggatgatg ggaccatttc tactattcgg ctctctcata aatggagcaa
    14281 cgatggttat gtacgaaggt gttcctgact ttccagaggc agatcgttta tgggagacgg
    14341 ttgataaata tgaaattaca catctcggta tatcaccaac attaattcgt gcgttaatgg
    14401 caaaaggtga tgagtatgtt aataaacatt cactaaagag tttagaagta ttcgcatcaa
    14461 caggtgaacc ttggaatcca gacccttgga tgtggctatt tgaaacagtt ggaaaaagta
    14521 atgtaccaat ttgtaactat tcaggcggta ctgaaatttc tggtggaatt ttcggaaacg
    14581 tccttattaa accaattgca ccgattagct ttaacgcttc tttaccagga atggcagcgg
    14641 ttgtgctcga tgatcaaggt aatccaattc gtgatgaagt tggagaatta tgtttagaga
    14701 aaccttgggt tggtatgacg aaaagcttct gggaagacga tgaacgctat gtgaacacat
    14761 attggtcacg ttttgaaaat aaatgggttc atggtgactg ggtgatttat gatggtgagc
    14821 aatatattat tacaggacgc tcagatgata cgttaaacat tgctggaaaa cgtattggac
    14881 ctgcagaata tgaatctatt cttgtgaagc ataatgatgt catagaagct gccgcgattg
    14941 gtgtacctga tgatgtaaaa ggtgaagttt gtcattgttt tgtagtatta agggacaatg
    15001 taacattcac aggagagtta aagaaagaat taatgagttt agtaaactct catatcggaa
    15061 aagcattgtg tccaaaagat attcacgttg tagaagattt accaaaaaca cgtaattcta
    15121 aagtaatgcg acgcgtcatt aaagctgctt acttaggaaa agaattaggt gatttatcat
    15181 cacttgtaaa tcctgaagta gttccgttta ttcaggggtt acagtctagc aaactataaa
    15241 attacgaatg agctctatgt aaatagagct catttttaat gtttacaaaa agataagaga
    15301 gaaaaagtaa atttgaagtt aaaaaatcta ctattagtgt taagtatgtc tgtgtttgtt
    15361 tttagttttt atcaaaatag gatactgttg catatctatc caatggagta attgaatttt
    15421 gttaagaatg aaaatttagt gaagaaaaaa gtaatgaata aaaggagaaa tccctggggg
    15481 acagggattc aataaaggaa atatcattgt cgttcaatgt cgaaatttgg cgtattagac
    15541 aaattaatat tatcacgaat tttcaggaga ttgtgatagt ggatgtgtca aaaatgtgta
    15601 cggttttcat ataaaagtgt taattaaata ggaaaaggga aaagaattaa gttcactcgt
    15661 tcttaagatt tttccctttc aaatttactg cttgttcgtt gttctatata catctgaaat
    15721 tggtaaatcg tcgccatgta aagcttgagt actgtccttt ttgtttgaat catgtgcctc
    15781 ctgagatgtt tcttgcattt gctcttgagc tttactagga gtattcagcg catccgatga
    15841 cacataatca agttgttgac ttaatagatt ttttttatcc atgttatgta gctccttttt
    15901 gaatttagat ataaaaacga agtgttttta aatagttacg tgggtattat gtttctttga
    15961 atggaattat atacataaac tatattgaga atttaactaa ttataaaaat cacttgtgat
    16021 gacaagttta agaaatataa agatcattag ttcttaataa aagctttatt ttagtagggt
    16081 gtttcgaaat ttcatttgaa aggaatatcc caatgataag atgagcactg taaatcagtg
    16141 ctcatcttat cagaaattgc ttagtactta aagataaaac cattacggac aattcacaat
    16201 ggtaatagta acgctagcca ttgttccagg agaatcaaga agtgaagcag taacggttac
    16261 tgttccaggc ccattagcgg ctagaaatac agcggtaaag ttacctgaag catttgtaat
    16321 gacagcaaga ggaaccatga aagcaagaga aggattacta aatgaaaaac tgaccactac
    16381 tcctggagta ggactaccgt ttactaatac ttgacccgaa aaaaataaag tattatttcc
    16441 ttgagtggat acacatgtcg tggtttcgtt agaagtcaaa gtaatagatg caggcccagc
    16501 aggaagatta aatccagttg gtccagttgg tccagttggt ccagttggtc cagttgaacc
    16561 agttgaacca gttggtccag ttggtccagt tggtccagtt gaaccagttg aaccagttgg
    16621 tccagttggt ccagttgatc cagttggtcc agttgatcca gttggtccag ttgaaccagt
    16681 tggtccggtt gaacccgtag ctcctgtaga accggtggga ccagtaggga attgaaaggg
    16741 ttgaacaggt ggaagtgtag gtccaataga ccccggatta agtgcagcaa aagataaaaa
    16801 ctcgtccatt atttatcacc tctaaaaatc gtattactaa tagtaaatgt aatgataaag
    16861 caaagtgaaa tggacaagcg gttgtatttt aataaattaa acaaaatttt tatttgatag
    16921 aaagagagat tagtatgatt cctttagaaa ttaaatataa aaaggcgagt attttcaaat
    16981 cgccttttgg gtaatgcagt gtaattttat tcagttattt taaaaatagt ttcattcggt
    17041 ttggaaaatc catacagttt ccttgcgaat tttaaaattt cttcttcact atctgttaaa
    17101 gctttaacat cattcttaag ggaatgacca tccttcttta aagaagataa tttttgttgc
    17161 tccgtattaa gcgtgatttg tttttcttta atcatttctt gttggttatt aagagaatat
    17221 tgaaggacaa aaatgatagg taatattaaa gccaaaatag ttataatacg gcgtcttgtt
    17281 tttttattat taccttgttg ggtgttaggg ttcacttgct gtgagggtat attaggattt
    17341 gattgttgtg atgatacatt tgggatgttt cccattaaaa tgcctccatt actgattgta
    17401 gaatttaaac catttaaaag tattataaat gttcaatagg gattttagaa gatattttaa
    17461 tataggtgag ttttgtaaag tttaaacaaa atttttattt aaataaaaga aaccccgatt
    17521 gtctatgggc tcttgaagat aatggttaag taatgaagta ctccactaat taaagatatc
    17581 atgaattttt tggtgaaaat actggttaat tcatccgaat taatgagagc ctcatttgaa
    17641 acaaaaatgc tattttaata gggaggggaa taatgatgat tccatgggac aagcgagtat
    17701 acattgtatc aaggtgatta ttttattaaa gaggggacaa ttttagaggt tagtgaaaag
    17761 gcgaataaat cattatattg gcttcggtgc atgttagctc caagctatga aaaagtgtgt
    17821 ggtaatagta caaagcgact ttggttgatt cggatagatg atgacgaaga atgatgtgaa
    17881 aatttcattt cgtagagaaa taaggtgatt aagggtgggc atagaatatg ccctatttgt
    17941 attaaaaaag agcagaattt cgcctatata taaagatgtt ggaattgttc taaagggggg
    18001 aatatctgaa atataaataa ttgaggggag tgaattaata atggaaacta gtactttttt
    18061 aggattgttt tggggatggg taacggttat cgtatcggga atacttttcg tacgtccatc
    18121 ggtactacgt gaattgaaaa aattagtggt tgaagacaga ggatttggta ttatgtatgg
    18181 ttttctatcg attttcctag ggttaggtag tgtaatccta cataatgtat gggtattcaa
    18241 ctggcagggg ttcctaactt ttattgcatg gcttgcatta ttaaagggaa tctacataat
    18301 tgcatatcct gaaccttcca agaaaacaga ctttgaagta agggtactat ctacacgtat
    18361 agtgctcgct atcattggcg ccttggcttt atggatgctt atagtaatct atataaaata
    18421 atctttttct aataaggaag ttaataaaat atgaggaaat tccataataa tactaatttt
    18481 agaatgttcc attgcgaaat ggtcagaaat tcttgcttac aaatcgtaca ttccctaatt
    18541 tatatgctca aaaatttata ggagcattag aatttgcgag tgttcgggat tttggtgtat
    18601 gtggtctttt agttagacaa aatggtgcgt acatttttaa aactcataga cggctggttg
    18661 aatcttggcg aagagcaata gattaaatac gattctttga tgtgaagttc gataaaaaag
    18721 tacagtagat tcatctattg gaggaaaacg tggtgtttct aaaaggaata atttacgttt
    18781 ctatgattca ccaacttggc aggataaaga cgttgctggt tctgttataa tgtatgatta
    18841 gagtttatta ttgatgcaaa agcaagtgtt aaaggaacat tacaatacaa gatgcacaat
    18901 agcaaaggaa aaacatactg ctggtaaata agcttatatg tatgtgaagt aattaaagag
    18961 tcgatttata agagtcagct tatttttcaa tactccactc aactagtaat tatagatgtc
    19021 agtttaaatc tctacgtgtt aatatataaa aagctgacta tatttagtca gctttttata
    19081 tattctagta tttaccggtc ccaaaagata tattctttcc tttaagttga catttaaaat
    19141 attaccaatg ttttctttta caatgacaac aaataaagaa acatttacag cgacacttat
    19201 ttcgtttaga actccaatca tcattgcaat gctgttcttt agatttccac caatcatcat
    19261 cacaatggtg tttttcttta gatttccacc aatcatcatc acaatggtgc tgttctttag
    19321 atttccacca gtcatcacaa caatgctttt tcttagaact ccagcaatca tttttccagg
    19381 acattctttt atacctccct tcaataggat tactattatt ctatgtttta gtaaaaaaat
    19441 ggcttgttta ttcacctatt attttccctt taaatgatag agtgctttct actagatata
    19501 gaatccatac aaactatgct aaattttaca aaatagtgga gagaactact ggttatgaga
    19561 ttgatcaata aacacttggt gaagaaaacg ttctgattat aaataatatc ttattttgga
    19621 gtatgttttt ctgaatgtat acttcaaaac agcaaaggaa aaatatacta tattactgca
    19681 aacaaagtct atgtatatgt gaagtaatag gaatagctgg agattcttta aaaagtcagc
    19741 ttattaataa aaaatttttt tgagaaaggg tctgtctaaa ttttaaattc agcagaatta
    19801 aatccaagtc caatcattaa acaggccttt aattgttaga ggtccgtttt gttattaata
    19861 aagaaaagaa tgttattgtc gttgaaagca cgtttatact aataatgcta catatttgga
    19921 gtatttgaat tgagtattca tacagtagta tattcgtttt taatatatat aaaaaggttt
    19981 agtacaagtg tttgtttttt ttgtttctat gcttttgtct cgtacacttt taagctattg
    20041 gacatacttt actaatagaa aggattaggg ggtgaggatt tgggttctcg atttaataat
    20101 tgtagaaaaa aatgtacgtg taaacatgat gattgttggg atgtttttga agagtgtaaa
    20161 aaagaacagc atgagaaatg tgacagctct tgtgtacaag gaattagaga cgaacttaaa
    20221 aaattaatta ataaaacagt gcgaattaac actgaaggac gtacttatat aggtactgtt
    20281 tcttctgtaa cttgcgatgt tgttaagctg gctgctattc ctggttcagt tgcagcaatt
    20341 atatctcttt gtaaaattga agcgatttta ccacctgcta caactgttgc tgatgagttt
    20401 gattttaacg gtgttgacgt agcaaataaa gagtaattat gctttattga ttgcaaagcc
    20461 attcttatga atggcttttt attttgttta aaagggaata tatttttcat atagaaataa
    20521 atttgaaggt gtataaaagg ttgtgtgaaa ggggaatgag agtgatcaag ctgaaacaat
    20581 ttacaagaac tgatttcaaa caattaataa attggattga ttgcgaagaa tttttaatac
    20641 agtggtcagg aaatgtattt acataccctt tacatgaaca acaattagaa aaatatattg
    20701 aaagcaaaaa tacgcttgca tttaaagtaa tagatgaaga gactagaaaa gtaattggtc
    20761 atatttcact tgggcaaatt gacaatataa ataaatctgc aagaattgga aaagtgttag
    20821 ttggtgatac gaaaatgcga gggcgttcta tagggaaaca tatgatgaaa gcagtattac
    20881 aaattgcatt tgaagaatta aaactacata gagtaactct aggtgtttat gattttaata
    20941 cgtcggccat ctcatgttat gaaaaagtag gatttgtaaa agaaggttta ttaagagaat
    21001 ccaaaaaagt aggagaaaca tattggaatt tatgggaaat gagtatgtta gaatatgaat
    21061 ggagtgataa aaaataatag ttttttataa ttatgttatg tcaattaaaa ggggtatggt
    21121 gggaagttat gaataaaaat actaaagtaa tttcagttgc agctgtttca ggaggaggta
    21181 aaactactgt tacagaaagt ttaactcaca agttaatgaa ttcaaaagca ctatattttg
    21241 atagttataa ctttgataat tgtcctgctg atatttgtaa atggattgat gatggagcaa
    21301 attatgatga atgggtactc acaccattaa ttaaggatat tcagcatctg ttacaaaata
    21361 gttatctaga ttatattatt gtagattatc cttttgcata cctaaatagt gaaatgcgac
    21421 aattcattga tgtaaccata tttatcgaca cacctttaga tattgcgatg gctagaagaa
    21481 ttttgcgaga ttttaaggaa gatacaatga gtgaaataca aaatgattta aagcactata
    21541 taacatatgc tagaaaagct tatttagagg cacttcatac cgtaaagcca aattcagata
    21601 ttgttttgga tggatcttta tctgtcgatg aaataattaa tcaaatttta gagtcactta
    21661 atcggagaga agtaattgtc aatggttaaa tgtatagagg aatatgtaca agttgatgat
    21721 tttaaaatgt attcaaaagt attccaagga aagcagttgc aacctgttat tataatggaa
    21781 gcaggttatg gcgattattc aaagacatgg gatcatattg ctgaagagtt gacggaatat
    21841 gggacggtac tttcatatga tcgagcggga ttagggaaaa gtgggaagag tttcaagaga
    21901 cgtattagtt ctgaaatggt aaaagattta agaagttgct tagagcaatt acaattgaaa
    21961 ccaccttata tttttgtagg acattctttt ggtggtataa atgcacgttt atttgcgact
    22021 ttttatcccg aagatatgtt gggaatcgtt ttggcggatt cgacaccaga aaattataaa
    22081 gaagattttc tgccaatcat gtctaatgaa tttcaagaag cttactataa acagtttgta
    22141 tatgaaagtt catatgaaga gtttacattt agtttaagtg aagtagatag atgttgtgaa
    22201 tcaatgaatg atattccact tgtcgtgtta gctgcgggta aaaaagcttt ttattcgtca
    22261 gatgaacaaa tgaaatggtt gcaattgcaa gaagaattat tacgattatc aagcaataat
    22321 aaatttgtaa ttgcaacaca aagcggtcac tatattcaaa aagatgagcc gtattatgta
    22381 atagatgcgg ttaagtggat tattgggtag gggagagata aatatgtaca ctttatttca
    22441 atacaattgg caagtaagag atgattggtt taagtggtgt gaacaacttt cagaggaaga
    22501 attgctccgc aagcgtgtag gtggtgtagg aagtatttta gaaacattat tccatattgt
    22561 cgatgttgaa tacagctgga ttaatgcgct tcaaggaaaa gaagataatg aaccgcagtt
    22621 taaagattat caatcaatcc aaaaagtgaa agcgttatct gatttatata aacgagaatt
    22681 agaagatttt ttacagttgt ggtcatctag cctagaatgt aagatattaa aagcttcgtg
    22741 gacagataaa acatatacat acggtgaagt gttaaggcat gtaattgtac atgaaattca
    22801 tcacattggt cagctatcta tatgggcgag agagctaaat cttcagcctg tttcagctaa
    22861 tttaattgga agaggactat agatttagaa accggcttgc actgtaaata caagccggtt
    22921 tttatatata agaagatttc ctagttgaaa tcctcggatt ttttctgacg tatatgtaaa
    22981 aacattaaaa aggtaataat gaagaaaatc aacaatgttt gtatgattaa atttttaaac
    23041 tgaagcaaaa ctgtccaaga tgtaacagca tctttaaaag cttggagtgc agagtacgag
    23101 gaaggatcaa aaccgtactg tagtaacttt tttgtttcaa taaaagtact gttttcttca
    23161 ttggagtcta atattacgga aataagtcta gtatctcctc gttttgctgt actgacaaaa
    23221 ctataattac cattagttga aaaactagtt tgtaagccgt caacaccttg gagtttaatg
    23281 tttttattaa gagaataaat cattttattt gtgttgaaaa cttttgagtc tttgaaggta
    23341 aattggtaag aggttagttt cgtaacattc aatacatctg gaaagtcttt tactaattgt
    23401 gtcgctagtt tagctacgtc tatagctgtt gtagttgatt gtttatttgt atcgttattc
    23461 attccagtag catttagaaa cggggatggt tgtgataact ttagttgttt tgctttctca
    23521 ttcattaaaa gtgtaaagtt atcttcgttt ccagcaatgt gttctgcaag ggcaagtgcg
    23581 gaacgattat tccctgtcaa aaacaatgca tgaagtaaat cacgaactgt cgttttatct
    23641 ttcgaagtta cttgtatagg actcgtttct gctcggaaaa cttcgttact tatttttact
    23701 aattcatcta actgtatttt tccttcattc agttgttcca tggtgatata ctctgtcatt
    23761 aatttagata aagtagctga ttgtatagga gtttcttcat tttttttata aacaacttca
    23821 cctgaattag catctattaa aatagctgat ttagcttgaa taattggacc atttacatag
    23881 aggtaaaaat ataaaacgat aagtgctgta ataacaaaag ataagaataa aattgtgaac
    23941 tttttcaaga attgcataag cgatcctcct actatgacat caataatact attgtaaaaa
    24001 ggaatgctta attaggaaga aagaaaaggt aaagaatttc taaagaatta taaaggatta
    24061 ttaaattttg gagtttaatg gaaaataaaa ggtccaattt cttatatggt aagaaattgg
    24121 acctaaaatt aagttgtatt aacatttata tggttgtagt tttacagtga aagttgtttt
    24181 tttatcatca ctatatactt caattgttcc tttatgcaat tccacaatac tttttgcaat
    24241 tgccaatccg agtccagatc caccagtgtt cgtagagcga gatttttcaa cgcgataaaa
    24301 acgttcaaaa atatgaggta aatccgtact aggaataggt tggccgtaat ttgttatatc
    24361 tatattaatc atattattgc tttcataggc agcaaggtcg atatatccac catcgtttcc
    24421 ataagcgata gcatttataa taagattttc aaacactcgt actaatttgt ctccatcagc
    24481 taataccatg agtttttgag atgggaaaga aggtcgacat tctatattag cttcttgaac
    24541 ttgtatgcgg aattgaacag ttaattgccc cagtagctct acaatatcaa tgggaacaga
    24601 atataaactt aactctttat tttgaacacg tgtatattca aacaaatcat tcattaatgc
    24661 gttaagacgg gttactttat cgtaaatgac ttgtatataa tggcgtaatt ccacttcatc
    24721 tctataatta tcatggtgga ttaaatttac gtatccaact atagaggtaa gaggagtacg
    24781 taaatcatgc gatacatttg taataagttc actttttgct tgttccgcct gtctttcttc
    24841 atcaatcgaa actttcaatt gttcaacaat gtgattaacc ccgcttgcta actcttccag
    24901 ataattatgg tttacgatag agactttatg attgaagttt ccatttgcaa tataacgaat
    24961 ctcttctatc atttttttaa tacaagtttc ataataaatc tttctttcat gacgataaaa
    25021 aatgtatagg taggatgaga aaatagaaaa taaaaacaaa taagatacaa tcatcatcca
    25081 tagagattcc tttattcctt tatatttttc atatccaaaa attcgaatga attcttttcc
    25141 aagctcgctt aacgtaagtg aactttcaat tacacttgta acgaggcgat atataattaa
    25201 ttcagtaata ggagtaagtg tgatagctaa catgaacca
//
