GCF_022430525.1_ASM2243052v1_genomic - 3 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP092519.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	NRPS	67,324	110,170
Region 1.2	RiPP-like	415,699	426,484
Region 1.3	NRPS-like	800,928	843,741	iturin	NRP + Polyketide	22%

Region	Type	From	To	Most similar known cluster	Similarity
Region 1.1	NRPS	67,324	110,170
Region 1.2	RiPP-like	415,699	426,484
Region 1.3	NRPS-like	800,928	843,741	iturin	NRP + Polyketide	22%

No secondary metabolite regions were found in these records:: NZ_CP092520.1; NZ_CP092521.1; NZ_CP092522.1; NZ_CP092523.1; NZ_CP092524.1; NZ_CP092525.1

Compact view

NZ_CP092519.1 - Region 1 - NRPS

Download region GenBank file

Download region SVG

Location: 67,324 - 110,170 nt. (total: 42,847 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000427.1	0.32	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000375.1	0.31	NRP	indigoidine	Streptomyces chromofuscus
BGC0000900.1	0.31	Other	ferrichrome	Aspergillus oryzae
BGC0001249.1	0.31	NRP	dimethylcoprogen	Alternaria alternata
BGC0001964.1	0.26	Polyketide	alkylpyrone-407, alkylpyrone-393	Cystobacterineae bacterium
BGC0001479.1	0.26	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001285.1	0.26	Other (Fatty acid)	pseudopyronine A, pseudopyronine B	Pseudomonas putida
BGC0001399.1	0.25	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000979.1	0.24	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E9
BGC0000980.1	0.24	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 22D11

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000427.1	0.66	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000375.1	0.65	NRP	indigoidine	Streptomyces chromofuscus
BGC0000900.1	0.64	Other	ferrichrome	Aspergillus oryzae
BGC0001249.1	0.64	NRP	dimethylcoprogen	Alternaria alternata
BGC0001964.1	0.60	Polyketide	alkylpyrone-407, alkylpyrone-393	Cystobacterineae bacterium
BGC0001479.1	0.60	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001285.1	0.60	Other (Fatty acid)	pseudopyronine A, pseudopyronine B	Pseudomonas putida
BGC0001399.1	0.59	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000979.1	0.58	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E9
BGC0000980.1	0.58	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 22D11

Similar known gene clusters

No matches found.

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 67323 - 110170:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (asn)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_83

Search NORINE for peptide: strict or relaxed

AMP-binding (412..778): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asn

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

NZ_CP092519.1 - Region 2 - RiPP-like

Download region GenBank file

Download region SVG

Location: 415,699 - 426,484 nt. (total: 10,786 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

No matches found.

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NZ_CP092519.1 - Region 3 - NRPS-like

Download region GenBank file

Download region SVG

Location: 800,928 - 843,741 nt. (total: 42,814 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001778.1	0.48	Other	showdomycin	Streptomyces showdoensis
BGC0000258.1	0.45	Polyketide	prodigiosin	Serratia sp.
BGC0000259.1	0.43	Polyketide	prodigiosin	Serratia marcescens
BGC0001627.1	0.43	NRP	isonitrile lipopeptides	Mycobacterium tuberculosis H37Rv
BGC0000867.1	0.37	Other	polyhydroxyalkanoic acids	Ectothiorhodospira shaposhnikovii
BGC0000352.1	0.36	NRP	fimsbactin A	Acinetobacter sp. ADP1
BGC0000866.1	0.36	Other	polyhydroxyalkanoate	Burkholderia sp. DSM 9242
BGC0000220.1	0.34	Polyketide	enterocin	Streptomyces maritimus
BGC0001120.1	0.33	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0001813.1	0.33	NRP	tyrobetaine	Streptomyces sp. NRRL WC-3703

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001778.1	0.57	Other	showdomycin	Streptomyces showdoensis
BGC0000258.1	0.56	Polyketide	prodigiosin	Serratia sp.
BGC0000259.1	0.54	Polyketide	prodigiosin	Serratia marcescens
BGC0001627.1	0.54	NRP	isonitrile lipopeptides	Mycobacterium tuberculosis H37Rv
BGC0000867.1	0.50	Other	polyhydroxyalkanoic acids	Ectothiorhodospira shaposhnikovii
BGC0000352.1	0.50	NRP	fimsbactin A	Acinetobacter sp. ADP1
BGC0000866.1	0.50	Other	polyhydroxyalkanoate	Burkholderia sp. DSM 9242
BGC0000220.1	0.48	Polyketide	enterocin	Streptomyces maritimus
BGC0001120.1	0.47	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0001813.1	0.47	NRP	tyrobetaine	Streptomyces sp. NRRL WC-3703

Similar known gene clusters

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 3, location 800927 - 843741:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location 800927 - 840416:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 5, location 801176 - 843741:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_717

Search NORINE for peptide: strict or relaxed

AMP-binding (7..408): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: pLFivGGPiK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 60% (weak)

ctg1_718

Search NORINE for peptide: strict or relaxed

AMP-binding (39..440): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: pLgivGGPmK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 50% (weak)