LOCUS       c00001_NZ_FMIX..       22502 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_FMIX01000004.1 Streptococcus timonensis strain Marseille-P2915,
            whole genome shotgun sequence.
ACCESSION   NZ_FMIX01000004
VERSION     NZ_FMIX01000004
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 16:08:54
            Original ID  :: NZ_FMIX01000004.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 584641
            Orig. end    :: 607143
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22502
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[594641:597143](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12502
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     cand_cluster    1..22502
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22502
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="1"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     CDS             3682..3966
                     /locus_tag="ctg1_602"
                     /transl_table=11
                     /translation="MMEDTYYQLEEALVQGFQTPEEYQAYKELKEHYEEVTGDYSFSIR
                     ELTSQLEIALQNHRGVDFEEHEKEEYLDLVQKLEEFDSSLATHYRQLID"
     CDS             3980..4276
                     /locus_tag="ctg1_603"
                     /transl_table=11
                     /translation="MNDLLLIPVIFLAVGGILILLWRLFLIASGLFLIGFISFLIFVEV
                     YGIYLFFTEPTLYFDDIRQHGLTSFTAVYLFINLMLVLGFSWRFINSKTKKSM"
     CDS             complement(4290..4487)
                     /locus_tag="ctg1_604"
                     /transl_table=11
                     /translation="MNKLKGENLRRALSHIERHKQAINTSNNSEDNDFHKLLLQFSYEV
                     YERIKANKKPYPNLDSDKVF"
     CDS             4647..5288
                     /locus_tag="ctg1_605"
                     /transl_table=11
                     /translation="MLNKVKTKALIGFGAVAATSFILMMGYTAGQHSTAKQSRKEIELA
                     AAKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELSSQN
                     DAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSDLKNANQSKTNQTETRT
                     VKLSYSKLPGKLLVNQVQVWKSGLDDLDKATPKTLEESSSVPSLPNTTTK"
     CDS             5298..6383
                     /locus_tag="ctg1_606"
                     /transl_table=11
                     /translation="MEIEECKQISILDVANRLGITFKQVSSSVYEHPEHDSFRIFSTTN
                     TFKWFSRDIQGDVIDFVRLVQGISFKEALAFLSEEPFQKEAVQEKRERPFYYPLKRIED
                     SNCSLARYYLTECRGISEEIVQRMIQQGLIAQASWKTNETVEPVIVFKSFDHRHKLQAA
                     SLQGIYKNHSLPRERLKTILKGSHGYIGISFDIGKPNRLVFCESFVDLMSYYELHQQNL
                     SDVRLVSMEGLKRSVVAYQTLRLIAEENQKLEFLDTVIPSKLLPLINTIRDTTSYFDNH
                     PDLLTLAVDCDDAGKDFSDKLSQAGLPVLLDLPDNESGKEKVDWNDILREKKSDLQLMI
                     ENAKETFGNPPVRQTSQCLEL"
     PFAM_domain     5907..6281
                     /aSDomain="Toprim_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13155.8"
                     /description="Toprim-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_606_0001"
                     /evalue="4.40E-05"
                     /label="ctg1_606"
                     /locus_tag="ctg1_606"
                     /protein_end="328"
                     /protein_start="203"
                     /score="23.8"
                     /tool="antismash"
                     /translation="FCESFVDLMSYYELHQQNLSDVRLVSMEGLKRSVVAYQTLRLIAE
                     ENQKLEFLDTVIPSKLLPLINTIRDTTSYFDNHPDLLTLAVDCDDAGKDFSDKLSQAGL
                     PVLLDLPDNESGKEKVDWNDI"
     CDS             6434..6667
                     /locus_tag="ctg1_607"
                     /transl_table=11
                     /translation="MTIIERLEEKVTRQESKVARETEKLAAYKEQLETAMFATFKRRQS
                     ISHMSFEEALDHAFGKERQFDDSEFRKDEMSE"
     PFAM_domain     6664..7041
                     /aSDomain="DUF5945"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF19370.1"
                     /description="Family of unknown function (DUF5945)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_608_0002"
                     /evalue="3.00E-28"
                     /label="ctg1_608"
                     /locus_tag="ctg1_608"
                     /protein_end="126"
                     /protein_start="0"
                     /score="99.0"
                     /tool="antismash"
                     /translation="MTKDWNFNQPLESKSENQEDPDKIAALFGNHQGGNDVNYEAAFQK
                     RKQAPVTESNSSSKPKVTEVRTGKETDITTSYQQHLKRLIADNNSDIQSSQKKIEELHT
                     LIDTKNKDNKKLQSIYDAISEL"
     CDS             6664..7047
                     /locus_tag="ctg1_608"
                     /transl_table=11
                     /translation="MTKDWNFNQPLESKSENQEDPDKIAALFGNHQGGNDVNYEAAFQK
                     RKQAPVTESNSSSKPKVTEVRTGKETDITTSYQQHLKRLIADNNSDIQSSQKKIEELHT
                     LIDTKNKDNKKLQSIYDAISELD"
     CDS             7086..7361
                     /locus_tag="ctg1_609"
                     /transl_table=11
                     /translation="MFTTFFKKNHDNSDVFKKLIHRLSDMSVQDLEKIDRLLDIIFTPN
                     QESQQIKTELTDREETLDDTLKEAKNQLHKEQLEKNLERFRKDGRK"
     CDS             7401..8075
                     /locus_tag="ctg1_610"
                     /transl_table=11
                     /translation="VLYFLYRLEKEVNILELTTKQEKQLGQTQWFHATLLRHLESLKKG
                     IDVKFNLGSELDFGPGFYITPDFEQARKFINKQVEVLNRSTSNNNIFDSEEEVGIIVEF
                     RISNFIEIFKNPDYHCHYFAKHKKSESDLDFAEFVVQNRENPDELQHHFDFIYGVQTDD
                     NPTQALARFRQNEITKEEMLAEFRKPYSFKQLSIHNQSFCDIMKIEKVYQSKTGEELQK
                     WQ"
     PFAM_domain     7563..8015
                     /aSDomain="DUF3990"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13151.8"
                     /description="Protein of unknown function (DUF3990)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_610_0003"
                     /evalue="3.20E-16"
                     /label="ctg1_610"
                     /locus_tag="ctg1_610"
                     /protein_end="205"
                     /protein_start="54"
                     /score="59.5"
                     /tool="antismash"
                     /translation="ELDFGPGFYITPDFEQARKFINKQVEVLNRSTSNNNIFDSEEEVG
                     IIVEFRISNFIEIFKNPDYHCHYFAKHKKSESDLDFAEFVVQNRENPDELQHHFDFIYG
                     VQTDDNPTQALARFRQNEITKEEMLAEFRKPYSFKQLSIHNQSFCDI"
     CDS             8066..8293
                     /locus_tag="ctg1_611"
                     /transl_table=11
                     /translation="MAVVSLENNIKLYSSELFQALLKASNYKLDKRIAQTVAEGYARNL
                     DYSDPELMHVGVTSVANNLLTKIKQEYFNV"
     CDS             9811..9915
                     /locus_tag="ctg1_612"
                     /transl_table=11
                     /translation="MEQMLFELELLPEDEVIVTGLPKYCSFTCLITGN"
     CDS             10001..12502
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 56.3;
                     E-value: 6e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_613"
                     /sec_met_domain="LANC_like (E-value: 7.6e-26, bitscore:
                     87.1, seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 2.5e-12, bitscore: 43.1,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLLEKEYLKCDKNFQHGDIWNYYYLSDNVPAQGWKIHISSQIKD
                     AVDIFKIVYKISQLNNCSFKVVKNLKELKKINSPREMSPTANKFITLYPNSESEAKSMI
                     FNLTSKLSEFKAPKILSDYQCGLHSPVHYRYGAFLKKQAYDEKNKKVIYLLLDESNNNY
                     VEDRRQNFPSLPSWKKDLFSEEEKKNYFQTAREISTKDSTINKYKMEKIIKRSNKGNVY
                     RAIRRSDGQKVIIKQSRPFVNYDDEGEWTAIDDIKNEAFMLKKLVNKTYTTNLIDEFYI
                     VDDYFIVQEMVDGLNFEEFIKETEANENIREKSLNNIVDIVNDVHELGYKLVDIGPTNF
                     IYTKKGDVILIDLEALTPIEDKVRRIKTPMMVNPDTDLTTSSVQQDYFSLALIGFFLLT
                     GDFLSFSKGDPKTGLSVFIKICHLIKIANLNNKITKQQEYWLYDLLMMSQGEKIKKIKH
                     LQDFPRDTLFNTPDFLSYFEKYNFKEEALNIKSYLITKSMDKLGRLFPSNEFGEFVSPA
                     SFQHGFGGFLFFMNKFYVVEDGDTVKEWITNLENYEASSYLHGSSLLFGEAGLLFGILD
                     RYEKTKEIYLIDISKRIVDNLMKIYDNISNFDFAIGKSGILLSLMKYYTIFNDKDLGEF
                     IKIRINDLYVLLDSDKKEGIYFYNFAHGCSGIAYVLTVYTDIFGDIRYQNKLQKFSDEI
                     SELLEEKLSSFSKLDNLGLSWCEGISGLILYLCLIDKERYSDVIYKSQLEMLQQYETMG
                     TTFCHGLSSLLQTAVYNKNQKVEQLIKRILLTRSYRKDNGLLLFQGEDGMNSYFDFGVG
                     SIGIYWVLLGYTFPFELSKGD"
     PFAM_domain     10643..11335
                     /aSDomain="Pkinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00069.27"
                     /description="Protein kinase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_613_0004"
                     /evalue="3.50E-11"
                     /label="ctg1_613"
                     /locus_tag="ctg1_613"
                     /protein_end="445"
                     /protein_start="214"
                     /score="43.1"
                     /tool="antismash"
                     /translation="RSNKGNVYRAIRRSDGQKVIIKQSRPFVNYDDEGEWTAIDDIKNE
                     AFMLKKLVNKTYTTNLIDEFYIVDDYFIVQEMVDGLNFEEFIKETEANENIREKSLNNI
                     VDIVNDVHELGYKLVDIGPTNFIYTKKGDVILIDLEALTPIEDKVRRIKTPMMVNPDTD
                     LTTSSVQQDYFSLALIGFFLLTGDFLSFSKGDPKTGLSVFIKICHLIKIANLNNKITKQ
                     QEYWLYDLL"
     PFAM_domain     11546..12307
                     /aSDomain="LANC_like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05147.15"
                     /description="Lanthionine synthetase C-like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_613_0005"
                     /evalue="1.40E-21"
                     /label="ctg1_613"
                     /locus_tag="ctg1_613"
                     /protein_end="769"
                     /protein_start="515"
                     /score="76.6"
                     /tool="antismash"
                     /translation="PASFQHGFGGFLFFMNKFYVVEDGDTVKEWITNLENYEASSYLHG
                     SSLLFGEAGLLFGILDRYEKTKEIYLIDISKRIVDNLMKIYDNISNFDFAIGKSGILLS
                     LMKYYTIFNDKDLGEFIKIRINDLYVLLDSDKKEGIYFYNFAHGCSGIAYVLTVYTDIF
                     GDIRYQNKLQKFSDEISELLEEKLSSFSKLDNLGLSWCEGISGLILYLCLIDKERYSDV
                     IYKSQLEMLQQYETMGTTFCHGLSSLLQTAVY"
     CDS             12504..13742
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 82.5; E-value: 5.1e-25)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_614"
                     /transl_table=11
                     /translation="MHIFLKNRAFRQLTVNEWVSSFGDTIFYLAFINYVSSYVFAPLAI
                     FLISLSETIPQVLQLFTGVIADFQKNRISKYISILFIKVLLYSGVALLLTSTDFSLFSV
                     FFICSMNLISDTIGFLAGYMLTPIYIRLINDDMTEAMGFRQSTSSIVRLIGNLSGGVFL
                     GLFSISTLAFVNVLTFLFAFLGSLLIRNRLKKEEEKIEVPPYVGMSSFFQHLKGSMKLL
                     MTMEDVMVLLWILSISQAVLMMVEPVSAILLIKHPFMGLSTGQSLAILIMISLLHVILG
                     GLLSGFLSKKISIRLNIYWSLLMEFLIVIGFLRGSFLLILLGSAGDALSAGVLSPRLQA
                     MIFGIIPEELMGSVQSSINVINLLIPAVLSLALVFLATSAGLKVVAFALIILLLIAVYL
                     VYQMKNLPNQEEV"
     PFAM_domain     12516..13085
                     /aSDomain="MFS_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05977.15"
                     /description="Transmembrane secretion effector"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_614_0006"
                     /evalue="3.00E-06"
                     /label="ctg1_614"
                     /locus_tag="ctg1_614"
                     /protein_end="194"
                     /protein_start="4"
                     /score="26.1"
                     /tool="antismash"
                     /translation="LKNRAFRQLTVNEWVSSFGDTIFYLAFINYVSSYVFAPLAIFLIS
                     LSETIPQVLQLFTGVIADFQKNRISKYISILFIKVLLYSGVALLLTSTDFSLFSVFFIC
                     SMNLISDTIGFLAGYMLTPIYIRLINDDMTEAMGFRQSTSSIVRLIGNLSGGVFLGLFS
                     ISTLAFVNVLTFLFAFLGSLLIRNRLK"
     CDS             complement(14349..15245)
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 177; E-value: 1.2e-53)"
                     /gene_kind="other"
                     /locus_tag="ctg1_615"
                     /transl_table=11
                     /translation="MDYKLISTYLDFCKTHKRLSSHTIRAYKNDLMQFYNSDYDNIEAY
                     IEQLTRSNIKTNTLRRKIACMKVFYNYLKYQNIIEENPFNQLRFQFRTEKVLPKTIPYD
                     ILKSIFIYLEQKVIVSKTDYQKQHAERNLLIISLLLSTGIRISELCHIHLKDINLSNKT
                     LQIIGKGKKERILFLGDQKTFNLLETYINKTRNESNDFLFPGKHSLKPLSEQSVRLLIK
                     RIVEQNNFSRTITPHMFRHSFATMLLDSDVDIRYIQQILGHSSISITQIYTHVSHSKQK
                     EILSSFNPISVIHSEIE"
     PFAM_domain     complement(14418..14903)
                     /aSDomain="Phage_integrase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00589.24"
                     /description="Phage integrase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_615_0008"
                     /evalue="6.40E-43"
                     /label="ctg1_615"
                     /locus_tag="ctg1_615"
                     /protein_end="276"
                     /protein_start="114"
                     /score="146.6"
                     /tool="antismash"
                     /translation="QKVIVSKTDYQKQHAERNLLIISLLLSTGIRISELCHIHLKDINL
                     SNKTLQIIGKGKKERILFLGDQKTFNLLETYINKTRNESNDFLFPGKHSLKPLSEQSVR
                     LLIKRIVEQNNFSRTITPHMFRHSFATMLLDSDVDIRYIQQILGHSSISITQIYTHVS"
     PFAM_domain     complement(15021..15227)
                     /aSDomain="Phage_int_SAM_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02899.19"
                     /description="Phage integrase, N-terminal SAM-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_615_0007"
                     /evalue="8.90E-08"
                     /label="ctg1_615"
                     /locus_tag="ctg1_615"
                     /protein_end="75"
                     /protein_start="6"
                     /score="32.4"
                     /tool="antismash"
                     /translation="STYLDFCKTHKRLSSHTIRAYKNDLMQFYNSDYDNIEAYIEQLTR
                     SNIKTNTLRRKIACMKVFYNYLKY"
     CDS             15341..16330
                     /locus_tag="ctg1_616"
                     /transl_table=11
                     /translation="MRESYSIELVNKGDDDDFLKALKIYDNVTPVTIKTDPNDFIYWVD
                     NPIEEFRINIFKIYCNEKLIGMTMTSFLSRTKTMILEYIAVEKSYRKNVVYLSCLNLLG
                     QYFSNEKNYSINYWATDINNDKNGQGTDSESKMFQIILDLEGYKKIDAPFKTPSLGMTD
                     IPGFEAYIMIKSTDNIKSLSKTIYGGIIKSIFFDYYFQWYQKLLSKNDFSEYQNELRST
                     YKKLEKSIDTISDPIQILDEGYKVFKETTGPTPITKSNNLSYILNGIYVYLVTAVISLS
                     LGVILSLITVHFAFNNITDKGEIIASIIAGTMAIPVIGSIFTNLNKKK"
     CDS             complement(16351..17067)
                     /locus_tag="ctg1_617"
                     /transl_table=11
                     /translation="MDKVNPDVVREFYNKHDQMWEINNWYKYSQNSIISFLQKQHYTGN
                     ILNAGSGGNTYGITSPMIHLDISEEKVKDIEDAVIGNLESSNLLQTNNFDSIICVGSVI
                     NYCNSYKVIENFQKWLKEDGDLILEFENSSSFEYLFTDYYDKPMSIVSTNYIDSNHVIY
                     IFSFDYIISLLKLNNFEIIEIAGFHILSSLALRFFNSENFASKFTFLDKFLNKIHYFKK
                     HSANIIIRCKTTSTKV"
     CDS             17356..18120
                     /locus_tag="ctg1_618"
                     /transl_table=11
                     /translation="MQEFYDKFCKKRENQDELYFFNGYQGEVELNRSNIDLQKESEVLL
                     VRYASPKSNFDRLRYTNFNYDEDTQKDNSFSFESELAKFEKDSQRFVPDLNKNKEVYFL
                     PTNLESIVKQIINGNRRKVPDILIPLIPNDIQRSFDFTFTPTQFEIVTYENIGQFATSF
                     IKLEEPSSVCEVKEQMDCIKHSINDKFVDGIDDYFVGDLDQGFGMMERDFKKKYTTPST
                     FHYNFVLKNNEKDSMVNLLKTLSEKFIPFPFE"
     CDS             18144..18713
                     /locus_tag="ctg1_619"
                     /transl_table=11
                     /translation="MIKQNINNFDKIMNIVEQNDIKMPLLAINEPIFGIVSHLDKIYTI
                     YVMQDRTLLKDNHLVDIKEILITEPNLTNLYKVIDGEISIHSFFSKSNNYSIGKIANKI
                     FPKVEINDFSKISNKIPSMDLHLNLNDYCTQYYKNNIKSRCKRLKEYNNFNNSLTFTNN
                     KNVEVKKQIEALDIHWELKDEIYSNR"
     CDS             18691..19146
                     /locus_tag="ctg1_620"
                     /transl_table=11
                     /translation="MKYIVIDNGCKINTLEYNTFEIDEYNSGETISESQEVNLSIKIGF
                     NKENILKRVLLLDVFVEGKHEAILLRNLHLDLFYEFEYKEEYNEAVLDSLDMYMIKHFL
                     TETDKIVKNITSLDQLTSFSLKDAITDVTEKVPANLSVTVEQVGHYK"
     CDS             complement(19400..19870)
                     /gene_functions="other (smcogs) SMCOG1238:transposase
                     (Score: 94.3; E-value: 1.5e-28)"
                     /gene_kind="other"
                     /locus_tag="ctg1_621"
                     /transl_table=11
                     /translation="LDNLKDLPIVYIDETGINLYFYRPYARAPRGEKVYEKISGRRFER
                     TSIVEGQVDGEFIAPMVYKESMTSDFFVKWFKTQLLPALKTSHVIVMDNASFHPKNILD
                     ELCIQDKHFFLPLPPYSPDLKPTEQAWAILKKKVTDLLREVPNFFECLERFF"
     PFAM_domain     complement(19451..19846)
                     /aSDomain="DDE_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13358.8"
                     /description="DDE superfamily endonuclease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_621_0009"
                     /evalue="2.00E-22"
                     /label="ctg1_621"
                     /locus_tag="ctg1_621"
                     /protein_end="140"
                     /protein_start="8"
                     /score="79.6"
                     /tool="antismash"
                     /translation="IVYIDETGINLYFYRPYARAPRGEKVYEKISGRRFERTSIVEGQV
                     DGEFIAPMVYKESMTSDFFVKWFKTQLLPALKTSHVIVMDNASFHPKNILDELCIQDKH
                     FFLPLPPYSPDLKPTEQAWAILKKKVTD"
     CDS             complement(19917..20237)
                     /locus_tag="ctg1_622"
                     /transl_table=11
                     /translation="MAYGTDFKQRALDYIKEGHSHVEAAKVFDVGVRTLFTWEKKLREQ
                     EHLERKKRVVKKRKIPLEELKAFVEAHPDAFLLEIAAHFDCAIPSVWAALKQIKVTLKK
                     DD"
     PFAM_domain     complement(19923..20237)
                     /aSDomain="HTH_Tnp_IS630"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01710.18"
                     /description="Transposase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_622_0010"
                     /evalue="1.70E-21"
                     /label="ctg1_622"
                     /locus_tag="ctg1_622"
                     /protein_end="105"
                     /protein_start="0"
                     /score="76.6"
                     /tool="antismash"
                     /translation="MAYGTDFKQRALDYIKEGHSHVEAAKVFDVGVRTLFTWEKKLREQ
                     EHLERKKRVVKKRKIPLEELKAFVEAHPDAFLLEIAAHFDCAIPSVWAALKQIKVTLKK
                     D"
     CDS             complement(20300..21172)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR01716"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_623"
                     /sec_met_domain="TIGR01716 (E-value: 5.6e-58, bitscore:
                     192.5, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LLGKWEIMKSKLGITLRKVRKGKQISLCSVADEHLSKSQISRFER
                     GESEISCIRLINILDKLHITLDEFLVLHNEDYTNAELFANLVQYIRKQYSSHNIKNIAA
                     LLSDSSLYTLNSFEKTMIKSILHTMDSSIIPSNKELLQLTDYLFKVEKWGYYEITLLGN
                     CVRTINYNSYFLLTKEMLNNYIYSSLNKTNKRIVTQLAINCLILSVDKEEFSNCTCLIT
                     EIKALLDNELNFYEQTVFLYATGYFEFKRHSDSGIEKMKQAIQVLDILGEDKLKLHYTS
                     HFYKLVNKK"
     aSDomain        complement(20306..20962)
                     /aSDomain="TIGR01716"
                     /aSTool="tigrfam"
                     /description="RGG_Cterm: transcriptional activator,
                     Rgg/GadR/MutR family, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_623_0001"
                     /evalue="1.80E-57"
                     /identifier="TIGR01716"
                     /label="ctg1_623"
                     /locus_tag="ctg1_623"
                     /protein_end="289"
                     /protein_start="70"
                     /score="192.5"
                     /tool="antismash"
                     /translation="VLHNEDYTNAELFANLVQYIRKQYSSHNIKNIAALLSDSSLYTLN
                     SFEKTMIKSILHTMDSSIIPSNKELLQLTDYLFKVEKWGYYEITLLGNCVRTINYNSYF
                     LLTKEMLNNYIYSSLNKTNKRIVTQLAINCLILSVDKEEFSNCTCLITEIKALLDNELN
                     FYEQTVFLYATGYFEFKRHSDSGIEKMKQAIQVLDILGEDKLKLHYTSHFYKLVNK"
ORIGIN
        1 taagggcatg gttgatttga gagagaccta tcaatcctta attgaaattc aacgtcatcc
       61 agattatagt cggacagatt ttcaggtatt acttagtaaa ctcaatcgtg actatgatcg
      121 ctttgtaagt caatttggat acttgaatgc ctcagtcaat cggaacttat ttgatagtga
      181 cgataagtat tccttactag caagtttaga agatgaatac attgattcta aagatcagaa
      241 agtaaaatat aaaaaatctt tagcctttga gaaagcattg gttaggccag agagagtgat
      301 tacaagagta tcaacggctt tagatgcctt aaactctagt ttatcggatg gtagaggggt
      361 tgatttagac tatatggtat caatttatcc cgaacatagc caagctgcta ttttagatga
      421 gttgggagac ctgattttaa tggatccaga aagttattta agaggagaaa gaaaatatct
      481 ttctaagaac cagtttttat caggagatat tctcaacaag atagaagtag ttcaactatt
      541 agtggaggaa aacaaccaag aatatgattg gagccatgct ttagatttgt tagaatctgt
      601 tcgccctcca aggattcatc tggcagatat tgagtttaaa atagggtcac gttggatacc
      661 tcaatctgtt tatggtaaat ttgcctttga atgttttacc aatcgtgaat ttgaattgtc
      721 ttcgcctgat gttgaacaag tcattgaagt gaatcctgtc gatggccaag ttcatttaag
      781 gacatcattt gcttatcgct atccaagtgc caaagatagt agtcttggag ttagtgggtc
      841 acgttatgat acaggaagaa agatttttga gaatttactt aattcgaacc aaccgactat
      901 tactatgact gttacggaag gagaaaagaa aaagactatc acagatttgg aaaaaacctc
      961 tgttctaaga gcaaaagagc agcatttaca agagctcttt caagaatttg tctcacggta
     1021 tccagaagtc caacaagtca ttgaagaaag ttacaatcgt ctttataatc ggacggttag
     1081 tcgagagtat gatggtagcc atctagtcat tgatggcttg gcacaaaaca tcagtcttcg
     1141 tcctcatcaa gagaatgcca ttcaaagaat cgtagaagaa aaaagagcct tgttagctca
     1201 tgaagtaggt tcaggaaaga ccttgaccat gcttggtgct gggtttaaat taaaggagtt
     1261 ggggatggtt cataagccct tgtatgtagt gccctctagt ttgtctgctc aatttggtca
     1321 agaaatcatg aaatttttcc ctactaaaaa agtctttgtg accactaaga aagattttgt
     1381 gaaggcgaga agaaaacaat ttgtttctcg tattattaca ggagattacg atgccattgt
     1441 cattggggat tctcaatttg aaaaaatccc tgtcagtaag gaaagacaga tgaattatat
     1501 cgaggataaa ctcaatgaac tacgagagat taaaacacat tctgaaaata agtacaccgt
     1561 taaagaagca gagcaatcaa taagtggtct tgagagacag ttggaagaac tccaacgctt
     1621 taatcgtgat agttttattg attttgagaa cttaggaatt gattttctct ttgtggatga
     1681 agcacatcac tttaaaaata tacgtccaat tactggactt ggaaatgtag cagggatcac
     1741 caatacaacg tctaagaaga atgtggatat ggaaatgaag attcgacaga ttcaggaaga
     1801 acatgatttt aaaaatattg tctttgcgac aggaacacct gtttcaaatt caattagtga
     1861 gctgtatact atgatgaact atattcaacc ggatatctta aaacgctatc aagttgatta
     1921 ttttgactct tgggtaggtg cttttggaga aattcaaaac tctatggaat taactcctac
     1981 aggggataag taccagccta agaaacgatt taaaaagttt gtcaatctac ctgagttgat
     2041 gaaaatctat aaagaaacag ccgacattca aacacaagat atgttggatt tacctgtacc
     2101 agaagcccat attatcccta ttgagagtga gttaactgaa aaccagaaac tctatttaga
     2161 agaattagtt atgaggtcag atatggtcaa atgtggaaca gttgatccga gtcaggataa
     2221 catgttaaag ataacaggtg aggcacggaa actagctatt gatatgcgtt tattggactc
     2281 tagttatagt ctagcagaca atcataaact gcttcaggta gtggataatg ttgaaagaat
     2341 ttatcgtgag ggaatggaaa ataaggctac tcagatgatt ttttcagata ttggaacacc
     2401 taagaaaaag gataatggct ttgatgtcta ttctgaaata aaggctttat tagttgatag
     2461 aggaatccct agtaaggaaa ttgcctttgt acatgatgcc aatagtgatg aaaaaaagaa
     2521 tagtttgtct cgaaaggtca atgcaggaga ggtgcggatt ctccttgcct caactgaaaa
     2581 aggaggaaca ggtttaaatg ttcagagcaa gatgaaagca gttcaccatc tggatgtccc
     2641 ttggagacca agtgatattc agcaacgcaa tggacggatt atccgacagg gaaatgaaaa
     2701 caaggaagtg gatatttacc actacattac caaaggttca tttgataatt atctatgggc
     2761 aactcaggag aacaaactcc gttatattaa gcagattatg acttctaagg agccgattcg
     2821 tgctgcagaa gacattgatg aacagactat gacagcttct gattttaagg cactagcaac
     2881 aggtaatcct tatctcaaat ataagatgga actagagaat gatctaactc tattagaaaa
     2941 tcaaagacgc gcctttcaac gcagcaagga tcactatcgt catacaatct cctactgtga
     3001 agaaaatatg cccattcttg agaaacgatt aagcaagtat gaaggcgaca ttcaacagtc
     3061 tgaaatgacg aaagaacagg cattttctat gacagtaggc aagcaagttt ttgagcaacg
     3121 agctgaagcg ggggaatcct tacaccgttt tatccgtcat aatcaagctg acagcaaaga
     3181 attccgtacc ctagcaagct atcgaggatt tgacattaaa atgcttagtc ttccaacgga
     3241 tcagcctctt cctgaaacct tctctgttaa gattgtagga gaaaatcaat attctgtcag
     3301 tttagatttg tattctcctt tggggacaat tcaaagactc caacatacga ttgatcacat
     3361 taaagaggac caagtgaaaa ctcagaactt attggatgaa ttaaaggata aatggaatac
     3421 tgctaaggta gaaattgaga aaaactttcc aaaggaagag gattatcaaa caaaaaaggc
     3481 cgaatacgat gtactcgcgc cattgattga aacggaaacg gatttagata ttattgatca
     3541 ggccttaaga caattccatg aaaaaggaaa agaaaagcaa gaacaacttt cttttgaatt
     3601 ggagtaagaa atagatacaa atagcggaca aaaaaagaaa agcgcggtag aataaagata
     3661 gaaagaaacg aggtaacgat tatgatggaa gatacctatt atcaattaga agaggctttg
     3721 gtacagggat ttcaaacacc tgaagaatac caagcctaca aggagttaaa ggaacattat
     3781 gaggaagtga caggcgatta cagcttttct atacgagaac ttactagtca attggaaatc
     3841 gctcttcaga atcatcgagg tgtggacttt gaagaacatg agaaagagga gtatttggac
     3901 ttagttcaaa aattagaaga gtttgattcc tctcttgcca cccattatcg tcaattgatt
     3961 gactagaaag gagaaagtca tgaatgattt actccttatc ccagtaattt ttttagcagt
     4021 aggaggaatt ctcattcttt tatggagact ctttcttatt gccagtggac ttttccttat
     4081 tggttttatc agttttctta ttttcgtgga ggtctatgga atttatctgt tctttactga
     4141 accgacttta tactttgatg atatcagaca acatggttta actagtttta cggctgtgta
     4201 ccttttcatc aatctgatgt tggttctagg attcagttgg cgtttcataa actccaaaac
     4261 taagaaaagt atgtaaactt gttagatggt taaaaaactt tatctgaatc taaattcgga
     4321 taaggttttt tattagcctt gattctttca tatacttcat aactaaattg gagtaataat
     4381 ttatgaaaat cgttatcctc actattatta cttgtattta tggcttgttt atgtcgttca
     4441 atatgagaaa gagctcttct caaattttct ccttttaatt tgttcatatt tatattataa
     4501 actgaagaca gctaattttg atatttttct ctgaactgta cgattttgcg cctgaaatgt
     4561 aggaattacc tttcgttgtg atgtgataaa acttacaagt tctttttgtt attcttgacc
     4621 tagtttttat agaaagaagg tctaagatgt taaataaagt caaaactaaa gccttaattg
     4681 gttttggagc agtggctgcg actagcttta ttctcatgat gggatatact gctggtcaac
     4741 attctactgc taaacaaagt cgcaaagaaa tcgaattggc tgcagctaaa cttgtagagg
     4801 acaaacaagc agaagataaa gccagcattt tgtcatcaga tactgtaaaa gaatttttga
     4861 cacagtacta tacgaaagaa aagctcggag aaaataatac acgtattcaa ccttatatga
     4921 ctgaatcagc ttattctcaa gaattgtcaa gtcaaaatga tgccatgaac caagtttata
     4981 aggactatat tttggattat cattttgaaa aagcagatat ctttgtcaat cagactacga
     5041 atcaagccat tgccatggtc tcttataatg taacctatgt atctgattta aagaatgcca
     5101 accaatcaaa gacaaatcaa acagaaacca gaactgttaa attgtcctat tctaaactac
     5161 ctggtaagtt attggtcaac caagtacagg tttggaaatc tgggttagat gatttagata
     5221 aggcaactcc caaaacttta gaagaatcct catctgttcc atcattacca aatactacaa
     5281 caaaatgatg atattgcatg gaaatagaag aatgtaagca aatttcaatt cttgatgtag
     5341 ccaatcgttt aggtatcacc tttaaacaag tttcgagcag tgtctatgaa catcctgaac
     5401 acgattcatt tcggattttt tcaactacca atacttttaa atggttttca agagatattc
     5461 aaggtgatgt cattgatttt gttcgacttg ttcagggaat ttcctttaaa gaagctctag
     5521 cctttctttc tgaagaacct tttcaaaaag aagctgttca agaaaaaaga gagagaccat
     5581 tttattatcc tttaaagaga atagaagatt ctaactgtag tctggccaga tattacttaa
     5641 cagaatgtag aggaatttca gaagaaatcg tacaaaggat gattcaacaa ggtttgatag
     5701 cacaagccag ttggaaaaca aatgaaactg ttgaacctgt tattgttttt aaaagttttg
     5761 atcatcgtca caaactgcag gcagcaagct tacaggggat ttataagaat cactctcttc
     5821 ctagagagag gctgaaaacg attctaaaag gaagccatgg atatattgga atatcctttg
     5881 atattggtaa accaaataga ctggtctttt gtgaatcgtt cgtcgatttg atgagctatt
     5941 acgaacttca tcaacaaaat ctatctgatg ttcgtttggt atctatggag ggattaaaaa
     6001 ggtctgttgt cgcttatcaa actttacgac tgatagctga agaaaatcag aagttggaat
     6061 ttttagatac agtaatacct tcaaagttat tgcctttaat caatacaatt cgtgatacaa
     6121 ccagctattt tgataatcat cctgatttat tgacactggc agtagattgt gatgatgcag
     6181 gtaaagattt ttctgataag ttatctcaag ctggattgcc tgttttactg gatttacctg
     6241 ataatgaatc tgggaaagaa aaagtagact ggaacgatat tcttcgagaa aagaaatcag
     6301 atttacaatt gatgatcgag aatgcaaaag agacatttgg aaatccacca gtaagacaaa
     6361 cctctcaatg tttagaattg tgataacaaa atcaagatgt tttagctaat attagaatga
     6421 aggaggatcg tatatgacca ttattgaacg cttagaagaa aaggtcacta ggcaagaaag
     6481 taaggtagca agagagacag aaaaactcgc tgcttacaaa gaacaactgg agacagcgat
     6541 gtttgcgacg ttcaaaaggc gtcaaagcat tagtcacatg agttttgaag aagctcttga
     6601 ccatgccttt ggtaaagaaa gacaattcga tgattctgaa tttagaaagg atgaaatgag
     6661 tgaatgacaa aagattggaa ttttaatcaa ccattagaaa gcaaatcaga aaatcaagaa
     6721 gatccagata aaattgcggc cttatttgga aatcatcaag gaggtaatga tgtaaattat
     6781 gaagcagctt ttcaaaagcg aaaacaagca cctgtgacgg aatcaaattc tagttctaaa
     6841 cccaaagtta cagaggttag aacaggaaaa gagacagata tcactacaag ttatcagcaa
     6901 catcttaaaa ggcttattgc ggataacaat agtgatattc aaagcagtca aaagaaaatt
     6961 gaagaactac atactttgat tgacactaag aataaagaca ataagaaatt gcagtccatt
     7021 tatgatgcga tttccgaatt agactaagca gtcctgatag gctgcttttt tttgagaggt
     7081 tatagatgtt tacaacattt tttaagaaaa atcacgacaa tagtgatgta tttaagaagc
     7141 taattcatag actatctgat atgtctgtcc aagatcttga aaaaatagac cgactgctag
     7201 atatcatttt cactccaaat caagaatcac aacaaataaa aacagaatta actgacagag
     7261 aagaaacttt ggacgacaca ttaaaggaag ctaagaatca acttcataag gaacaattgg
     7321 agaagaattt agagagattt aggaaagacg gaaggaagtg aatagtttta taaaattttc
     7381 ttttactgga ataaattctt gtgttatact ttttgtatag actagagaag gaagtaaata
     7441 ttttggagtt gactaccaag caggaaaagc aactaggtca gacgcagtgg tttcatgcta
     7501 cattattgag acatttagaa tccttaaaaa aaggaatcga tgttaaattt aatttaggaa
     7561 gtgagctaga ctttggacct ggtttctata tcacacctga ctttgaacaa gctagaaaat
     7621 ttattaacaa gcaagttgaa gtattaaatc gaagcacctc taataataat atttttgact
     7681 cagaagaaga agtaggaatt atagtagaat ttcgtatttc aaattttata gaaattttta
     7741 agaaccctga ctatcattgt cactattttg caaaacataa aaagtcagag tcagatttag
     7801 attttgctga atttgtcgtt caaaatcggg aaaatccaga tgaattacaa caccattttg
     7861 attttatcta tggtgttcag actgatgaca atccaaccca agctttagct cgttttcgtc
     7921 agaatgaaat tacaaaagaa gaaatgcttg ctgagtttag aaaaccatat tcttttaaac
     7981 aattatccat ccacaaccaa tctttttgtg atataatgaa aatagagaag gtttatcaat
     8041 caaaaacagg agaggagtta caaaaatggc agtagtatca ttggaaaata atattaaact
     8101 atatagttca gaattatttc aagcactatt aaaagcctct aattataaat tggataagcg
     8161 tattgctcag actgttgcag aaggctatgc tcgtaatcta gattattctg atcctgaact
     8221 gatgcatgtt ggtgtaactt cggttgctaa caatctgctt acaaaaatta aacaagagta
     8281 ttttaatgta tagtattttg aaaagccacc gaaaaaggaa ttactcttta aggtggcttt
     8341 tttagaagta aagtttaggc tagaaaaaca agaagtaacg caccaaaaat ggtgcatttc
     8401 ttttttctaa atgttatggc tctttgtcaa ctgtagtggg ttgaagaaaa gctaagatct
     8461 agaaaggaca catttcattc tttctttttt gatgttcaga gcgataaaaa tccgtttttt
     8521 gaagttttca aagtttcgaa aaccaaaggc atttcgtttg atgagtttaa tgagattatt
     8581 agtcgctttc aatttggcgt tagaataggg tagttgaagg tcgttgacgt tccaaaggaa
     8641 acagcacaac tcttgaaaag tatgggagat gaagtacaat tagctttgat tgcgacaaag
     8701 ccatctgagc acccttatcc gttatgaaga actgtacgct atcaattcag atcaagcacg
     8761 cgcaactcta aaagaacatc atgatttcat tgtaaatcat ctagttgata atacaagaca
     8821 attggaaaaa ctagctatct ttgaaagaat tcaaatttac caacgagata gaagttgtgt
     8881 atatgattca agagaagaca aaacttcagc agcaaccgtt ctacatgatt tactatttgg
     8941 agaatggaat caagtcgaga aagagatgct taaatctgga gaagaaagat tgaaagattt
     9001 aactaatcga aatggtagtt agaacacaaa ttttaaaata taatctactt ataacttttg
     9061 ttagttgttt gaggtggtcg aaaagtcttt agaatcaaaa aaacgcatag tattaggtgt
     9121 tgaaacttga tactatgcgt tttcttcagg aattgagatt ttgcccatct ctttttatta
     9181 tatttaagga tacttgaaag ttatatttta gaaaaacaat tatggagttc taaatacgga
     9241 atatagtata aatgcggatt caaatttatt gagaagagaa attctccaaa ggaaaagaac
     9301 cccacaagaa aaatcgatat agataagtcg ctattattca gaaatgagtc aaattaattt
     9361 atattatttt agaatcatat ttaaattctc ttgtgcttat tagattttga attctatcaa
     9421 gtggtatatt cattatttat gtgttttatg aacggtgcat tattttcaca caaaaatgta
     9481 ggctttaaca tcgtatattt ttctgtgatc tgcgtatttg aaatataaaa tggttttaat
     9541 aaatttcgtt ttgttatttg gaaaattata aattttaaaa cttattattg aattttcaga
     9601 actatcggaa aaataaaaat aaacagtata ttcagaaaac tattgacaca caaaaaaaca
     9661 agtgctaaaa tgtacttaga aagttagagg aactaaaagt tatctaaatt ttatatttaa
     9721 aggtggtatt tagataaaaa agtttagtca gacgaaccac tagcttgctc tatgctttct
     9781 ggagtttttt taaaacagga ggataagaaa atggaacaaa tgttgtttga attggaactt
     9841 cttccagagg atgaagttat tgttactggt ctccctaaat attgttcttt tacttgttta
     9901 attacaggta attaattata ctttgtttaa aataagtatc tttacttaca aaataggcta
     9961 gtgctgtgtc tctagccttt tttaataata ggagtttgtt atggatttat tagagaaaga
    10021 atatttaaaa tgtgataaaa attttcaaca tggtgatatt tggaattact attatttatc
    10081 agataatgtt cctgcacaag gatggaaaat acatataagc tcccaaataa aagatgctgt
    10141 agatattttt aagattgtgt ataaaatatc ccaactaaat aattgtagct ttaaagttgt
    10201 taaaaattta aaggaattaa aaaaaattaa ttccccaaga gaaatgagtc ctacagctaa
    10261 caagtttata actctatatc ctaattcaga atctgaagct aagagtatga tttttaatct
    10321 tactagtaaa ttatcagaat ttaaggcccc caaaatacta tctgattatc aatgtggact
    10381 acattctcca gttcattata gatatggggc ttttttaaaa aaacaagctt atgatgaaaa
    10441 gaataaaaag gtcatttatt tattgttaga tgaaagtaac aataattatg ttgaagatag
    10501 acgacaaaat tttcctagtc ttcctagttg gaaaaaagat ttgttttcgg aagaagaaaa
    10561 aaagaattat tttcaaactg cacgtgaaat atcaaccaaa gactctacta taaataaata
    10621 taaaatggaa aaaattatta agagatcaaa taaagggaat gtttatcggg cgattagaag
    10681 atcggacgga caaaaagtaa ttatcaaaca atcaagacct tttgtgaatt acgatgatga
    10741 aggagaatgg acagctattg atgatataaa aaatgaggct ttcatgctaa aaaaattagt
    10801 caataaaact tatactacta atttaattga tgaattttat atagtggatg attattttat
    10861 tgttcaagaa atggttgacg ggttaaactt tgaagaattt attaaagaaa cagaagctaa
    10921 tgaaaatatt agagaaaaat cgttaaataa tatagttgac atagtaaatg atgttcatga
    10981 attgggatat aaacttgtag atataggtcc tacaaatttt atatacacta aaaaaggtga
    11041 tgtaatatta atagatttgg aagcactgac tcctattgag gataaggtga gaagaatcaa
    11101 aactccaatg atggttaatc cagataccga cttaactacc agttcagttc agcaagatta
    11161 ttttagttta gcactaatcg gatttttttt gttaactggt gattttttat ctttttcaaa
    11221 aggtgatcca aaaacaggat tatcggtctt tataaaaata tgtcatctaa taaaaatagc
    11281 gaatttaaac aataagatca ctaaacaaca agaatactgg ctatacgatt tattaatgat
    11341 gagccaagga gaaaaaatca aaaaaataaa acatttacag gattttccaa gagacactct
    11401 ttttaatact ccagattttc taagttattt tgaaaaatat aattttaaag aagaagcctt
    11461 gaatataaaa tcatatttaa tcactaaatc tatggataaa ctcggtcgtt tgtttccatc
    11521 aaatgagttt ggtgaattcg taagtcctgc atcttttcaa catggctttg gagggttttt
    11581 attttttatg aataaatttt atgttgtgga agatggagat actgttaaag aatggattac
    11641 aaatttagaa aattatgagg caagtagtta tttacatggt tcctctctat tatttggtga
    11701 ggcaggatta ctatttggaa tattagatag gtatgaaaaa acaaaggaaa tatacttaat
    11761 agatataagc aagagaatag ttgataattt aatgaaaatt tatgacaata ttagtaactt
    11821 tgattttgct ataggaaagt ctggtatctt actcagctta atgaagtatt atactatttt
    11881 caatgataaa gatttaggag aatttatcaa aataaggata aatgatttat atgttttatt
    11941 agattctgat aagaaagaag gtatatattt ttataatttt gcacatggtt gctcaggtat
    12001 tgcctatgta ttaacagtat atactgatat ttttggagat attcgttatc aaaataaact
    12061 acaaaaattt tctgatgaaa tatctgaatt gctagaagaa aagctttcaa gtttttctaa
    12121 attagataat ttaggtcttt cttggtgtga aggaatctca ggattaatat tatatctttg
    12181 tttgattgat aaagagagat actctgatgt aatctataaa tcacaacttg aaatgctaca
    12241 acaatatgaa actatgggaa ctactttttg tcatggttta agtagtttat tgcaaacagc
    12301 agtatacaat aaaaatcaaa aggttgaaca attgataaaa agaattttat tgacccgttc
    12361 ttatcgtaag gataatggac tattgctatt tcaaggagaa gatggaatga atagttattt
    12421 tgactttggt gtgggaagta taggtattta ttgggtttta ctcggttata catttccatt
    12481 tgaattaagt aaaggagact aatatgcata tttttcttaa aaatagggct tttcgtcagc
    12541 taacagtgaa tgagtgggtt tcaagttttg gagacactat tttttactta gcttttatca
    12601 attatgtctc ttcttatgtc tttgctccct tagctatatt tttgattagt ctgtcagaaa
    12661 ccattccaca ggtcttgcag ctttttactg gggttatagc tgattttcaa aaaaaccgaa
    12721 ttagcaagta tatttctatc ctctttatca aagtcctcct ctattctgga gtggctttgc
    12781 tcctgacaag taccgacttc tctctctttt ctgttttctt tatttgcagc atgaacttaa
    12841 tttcagatac gattggtttt cttgcagggt acatgttgac accgatttac atacggctaa
    12901 taaacgatga tatgacggag gctatgggtt ttaggcagtc cacgagttcc attgtacgtt
    12961 tgataggtaa tctcagcgga ggagtctttt taggactgtt tagtatttct actctagctt
    13021 ttgtaaatgt tttaaccttt ttatttgctt ttctgggaag tctccttatc cgaaaccgct
    13081 tgaaaaaaga ggaagaaaaa atcgaagttc ctccttatgt aggaatgagt agctttttcc
    13141 agcatttgaa agggtcaatg aaattattga tgactatgga agatgtcatg gtcttgcttt
    13201 ggattttgtc tattagtcaa gctgttttga tgatggtaga gcctgtcagt gcgatcctac
    13261 tgattaaaca tccgttcatg ggtttgtcaa cagggcaaag cctagcaatt ttgataatga
    13321 taagccttct ccatgttatt ttaggtggac ttctgagtgg attcttatct aaaaaaattt
    13381 ctattcgcct gaatatttat tggagtctat tgatggaatt tctcattgtt ataggttttc
    13441 tacgtggaag ttttttactt attttactcg gaagtgcagg ggatgctctc tcggcaggag
    13501 tcttgagtcc tcgcttgcaa gccatgattt ttggaatcat tcctgaggag ttaatgggat
    13561 cagttcaatc atccatcaat gttatcaact tgcttatccc agctgtccta tcccttgctc
    13621 tcgtatttct tgcaacaagt gctggtctga aagttgttgc ttttgctctt ataattttac
    13681 tacttatagc agtctatcta gtttaccaga tgaaaaactt accaaaccaa gaagaagttt
    13741 agctagaatg ttatggatag gtcagttttt acttgagagt tttatggaat cgtattctct
    13801 ttgtatttga ttatagatat ttcttacaac tgttttgaac taaaaatgat aaatttttag
    13861 gttaagttag ttaaaaagaa gaaattcttt gtctaatttg tagtccaaat atttttttga
    13921 tagttattaa tctaaattct ggctctttgt caactgtagt gggttgaaga aaagctaaga
    13981 tcgagaaagg acacgtttcg tcctttcttt tttgatgttc agagcgataa aaatcttttt
    14041 taagttttca aagttccgaa atccaaaggt atttcatttg ataagtttga tgagattatt
    14101 ggtcgcttct aatttggcgt ttgaataggg tagttgaagg gcactgacaa tcttctcttt
    14161 atctttgagg aatgttttaa agacagtctg aaaaaatgga gttcttaata cggaatatag
    14221 tataaatgct gattcaaagt gaagttttat atgttttttg cttttgttga gtataaaatc
    14281 tattaactac agtcgaacta caaaaattaa tttaagatga agtgaactgt agactttgga
    14341 gatgtctctt actcgatttc agaatgaatt actgatatgg gattaaaaga actaagtatt
    14401 tctttttgtt ttgaatgaga tacgtgagta tagatttgtg tgattgatat agaactatgt
    14461 ccaagaattt gttgaatata tcgaatatct acatcactat ctagaagcat tgtcgcaaag
    14521 ctatgtctaa acatatgcgg tgtaatagtt ctagaaaagt tattttgttc aacgattctc
    14581 tttattaata aacgtacact ttgctctgac aatggtttaa gtgaatgttt ccctggaaac
    14641 aagaaatcat tggattcatt ccttgtttta tttatatatg tttctaataa attgaatgtt
    14701 ttttgatctc ctaaaaatag gatacgttct ttcttaccct ttcctataat ctggagtgtc
    14761 ttattggaaa gattaatgtc tttgagatga atgtggcaaa gttcagaaat tctgatgcct
    14821 gttgaaagta aaagtgaaat aattagtaga tttctttcag cgtgttgttt ttgatagtca
    14881 gttttagata caattacttt ctgttctaaa tatataaaaa tgcttttcaa aatgtcatac
    14941 ggaatcgttt taggcaatac tttttcagtt ctaaattgaa agcgcaattg attgaaggga
    15001 ttctcttcaa ttatgttctg gtattttaga tagttataaa acaccttcat acaagcaatt
    15061 tttcttctta atgtattcgt ttttatgtta gatcgtgtca actgttctat ataggcttcg
    15121 atattatcat agtctgagtt ataaaattgc ataagatcat tcttataagc gcgaatcgtg
    15181 tgtgaactca aacgcttatg agttttgcaa aaatctaagt aagtagaaat aagtttataa
    15241 tccataaaaa tctcctttat cattaatcat gctattataa acctatttga gtgctttgta
    15301 tagtgataat aaattgttat cggtaggaga gagaaaattt atgagagaaa gttattctat
    15361 agaactagtt aataaaggcg atgatgatga ttttttaaaa gcattaaaaa tctatgataa
    15421 tgttactcca gttactatta agactgaccc aaatgacttt atttattggg ttgacaatcc
    15481 tatcgaagag tttagaataa atatttttaa aatatactgt aatgaaaaac ttattgggat
    15541 gacaatgact agttttctta gtcgcacaaa aacaatgata ttagaatata ttgcagtcga
    15601 aaaatcatat cgaaaaaatg tcgtatatct ttcttgtcta aatctgctcg gacaatattt
    15661 cagtaatgaa aaaaattact ccattaatta ttgggccact gatatcaaca atgataagaa
    15721 tggccaagga actgattctg aaagcaaaat gtttcaaata atcctagatc ttgaaggata
    15781 taaaaaaatt gatgccccgt ttaaaacacc cagcttaggt atgactgata taccaggatt
    15841 tgaggcgtac attatgatta aatcaacaga taatatcaaa tcactttcta aaacaatata
    15901 cggaggcata ataaagtcta tattttttga ctattacttc caatggtatc agaaactatt
    15961 atccaaaaat gacttttcag aatatcaaaa tgaattaaga tcaacttata aaaaattaga
    16021 aaaaagtatc gatacaattt ctgaccccat ccagatttta gatgagggtt ataaagtctt
    16081 taaggaaaca actggaccta ctccaataac taaatcaaat aatttgagtt atatattaaa
    16141 tggaatatat gtatatttgg tgacagctgt tatatcttta tctttaggag taatattaag
    16201 tctaattact gtacattttg cttttaacaa tataactgat aaaggtgaaa taattgcttc
    16261 tatcattgct ggtacaatgg caattccagt aataggtagc attttcacta acttaaataa
    16321 gaaaaaataa taataataaa caactagcat ttaaacttta gtgctagttg ttttacatct
    16381 tataatgatg ttagcagaat gttttttaaa ataatggatt ttatttaaaa atttatctag
    16441 aaatgtaaat ttactcgcaa agttttcaga attgaaaaat cttagagcta gcgaactcaa
    16501 gatatgaaaa ccagcaattt caataatttc aaaattgttt agcttcaaaa gggaaataat
    16561 ataatcgaag gagaaaatat atataacatg attggagtca atgtaatttg ttgaaacaat
    16621 tgacataggt ttatcataat aatcagtgaa aagatattcg aaagaactac tattttcaaa
    16681 ttcaagaatt aaatctccgt cttccttaag ccatttttga aaattttcta taactttata
    16741 agaattgcaa taattaatta cactgccaac acaaataata gagtcaaaat tatttgtctg
    16801 aagaagatta gaggattcta agtttccaat aactgcatct tctatatctt taaccttttc
    16861 ctcagaaata tccaagtgta tcattggcga tgtgatacca taagtatttc cacctgaacc
    16921 tgcatttaaa atatttccag tatagtgttg tttttgcaaa aatgagataa tagagttttg
    16981 actgtattta taccaattat ttatttccca catttgatca tgtttattgt aaaactctct
    17041 gactacatca ggattaactt tatccattct ctattcaatt ctcctaccga taacaattta
    17101 ttatcactag tataccataa attcatcttt aacagtttga tttgtataat gatttttttg
    17161 tcttgaattg aaaaaattac ctattgaact atcataaaaa attgaaataa taacaaatat
    17221 ttgatagaat ggtatagtat agtttatagt tttagctaga aatgactata tctaaaattg
    17281 attacccatt ttaagaaata tatgggtatg attaaacata ttattatttt tgaataattt
    17341 tagagtaaag agaaaatgca agaattttat gataaatttt gtaaaaaaag agagaaccaa
    17401 gatgaattat atttctttaa tggatatcaa ggagaagttg aattaaacag aagtaacata
    17461 gacttgcaaa aagaatccga agttcttctt gtaagatatg ctagtccaaa atcaaatttt
    17521 gacaggttgc gatatacaaa ttttaactat gatgaagata ctcaaaagga taattcattt
    17581 tcatttgaat cggaacttgc aaaatttgaa aaagattcac aacgatttgt tccagatttg
    17641 aataaaaaca aggaggtgta tttccttccg acaaatctgg aatcaatagt aaaacaaata
    17701 attaatggta atagaagaaa agtacctgac attctaattc ctttaattcc aaatgatatt
    17761 cagaggagct ttgattttac atttactcct acgcaattcg aaattgttac ttatgaaaat
    17821 attggtcaat ttgctacttc atttattaaa ttagaagagc cctcgagtgt ttgcgaagta
    17881 aaagaacaaa tggattgtat aaaacacagt ataaatgata agtttgttga tggtatagac
    17941 gattactttg ttggtgattt agatcaagga ttcggaatga tggaacgtga ctttaaaaaa
    18001 aaatatacta caccaagtac ttttcactat aattttgtat tgaagaacaa tgaaaaggat
    18061 agtatggtga atttactaaa aacattaagt gaaaaattta taccatttcc gtttgaataa
    18121 aaaatgagtg gaggaaaaat aatatgataa agcaaaatat aaataatttt gataaaatta
    18181 tgaatattgt agagcaaaat gatataaaaa tgcctttact agcaataaat gaaccgatct
    18241 ttggtattgt atctcactta gataagattt acacgattta tgtcatgcaa gataggactt
    18301 tgttgaaaga taatcatttg gtagatatta aagaaatttt aattactgaa cctaacctta
    18361 ctaatcttta caaagtaata gatggtgaaa tttcaattca tagtttcttt tcgaaatcta
    18421 ataattatag tattggaaaa attgctaata aaatttttcc aaaagtggaa attaatgatt
    18481 tttcgaaaat ttcaaataaa attccttcaa tggatttaca tttgaatttg aatgattatt
    18541 gtacgcaata ctacaaaaat aacataaaaa gtcgctgtaa gcgtttaaaa gaatacaata
    18601 actttaataa tagtcttact tttacgaata ataaaaatgt ggaagtgaaa aaacagatag
    18661 aagctctaga tatacattgg gaacttaaag atgaaatata tagtaataga taatggttgt
    18721 aaaattaata cattagagta taatacattt gagatagacg agtataattc tggtgagaca
    18781 atttcagaga gccaagaagt taacctttct ataaaaatag ggtttaataa ggagaatata
    18841 ttaaaaagag ttctattatt agatgttttt gtagaaggta aacatgaagc tatcttatta
    18901 cgtaatcttc atttagattt attttacgaa tttgaatata aagaagaata taatgaagct
    18961 gttttggata gtctagatat gtatatgata aaacattttt taacagaaac tgataaaatt
    19021 gttaagaata taacttcatt agatcaatta acatcttttt ctttaaaaga tgcaataaca
    19081 gatgttacag agaaagtacc agcgaatctt tctgtaacgg tggaacaagt tggtcattat
    19141 aaataatttt taagtttaac atattatttt aaagatagct tagagtcaaa accactttat
    19201 aaagtataat aaaaagttct ttaataaaat gagctctttg taagctatag tggattgatg
    19261 aaaagttata aaaagagagg atcaaatcgg tccaatataa ttaagccaga aattcaaata
    19321 cgattctgta tttgggtttc tttttttatg ggctaaactg atagttaagg aggtgctttc
    19381 catgatatag tcatttagtt taaaaaaagc gctccaagca ttcaaaaaaa tttggaactt
    19441 cccttaataa atccgtcact ttctttttca agatagccca agcttgctca gtaggcttca
    19501 aatctggtga ataaggtggt agaggtaaga aaaagtgttt atcttgaatg caaagttcat
    19561 ccaaaatgtt cttgggatga aaactagcat tgtccatgac aataacatga gatgtcttca
    19621 aagcaggcag gagttgcgtt ttgaaccact tcacaaagaa gtcactcgtc atgctttcct
    19681 tgtaaaccat gggagctata aactctccgt ctacttgtcc ttcaacaatt gaagtccgct
    19741 caaaacgccg tccgctaatc ttttcataga ctttctcccc tctaggagcc cgtgcataag
    19801 gacgatagaa gtagagattg attcccgttt cgtcaatata tacgattggt aagtctttta
    19861 ggttatccaa aatatcaaga aattcagcga ctttctctgg attttgtttc ttaaagctag
    19921 tcgtcttttt ttaaagtgac cttaatctgc tttaaagctg cccatactga aggaatagca
    19981 caatcaaaat gtgctgcaat ttccagtaaa aaagcgtctg gatgagcctc tacaaaggct
    20041 ttcaattcct ctaaaggaat ctttcgcttt ttgacgactc gctttttccg ctctaagtgt
    20101 tcttgttcac gtaatttttt ttcccaagtg aagagagttc tgacgccaac atcaaaaact
    20161 ttggctgcct cgacatggct gtgtccctct ttgatgtaat ctaatgctcg ttgtttaaaa
    20221 tctgtaccat atgccatagc tttattatga catgcccgtt tgaaactaag caactataaa
    20281 tggtagagaa tcatttcatc tattttttgt ttaccagttt atagaaatgg ctagtatagt
    20341 gtaattttaa cttgtcttct cctaaaatat caaggacttg tatggcctgt ttcatttttt
    20401 caattccgct atctgaatga cgcttaaatt caaagtaacc agttgcatag agaaaaactg
    20461 tctgttcata aaagtttaat tcattatcta ataatgcttt tatttcggtg attagacaag
    20521 tacagtttga aaattcttcc ttatctacgc tcagaattag acaattaatg gccaattgag
    20581 tgacaattcg cttatttgtt ttattcaatg aagagtagat gtaattgttc aacatttcct
    20641 ttgttaatag gaagtaggag ttgtagttta ttgttcgtac acagttacct aataaagtga
    20701 tttcatagta accccatttt tcaactttaa agagataatc tgtcaattga agtaattctt
    20761 tatttgatgg aataatgctg gaatccattg tatgtagaat ggattttatc attgttttct
    20821 cgaaagaatt taaagtgtaa agtgatgagt cagaaagtag agcagctata tttttgatgt
    20881 tatgtgatga atattgctta cgaatatatt gaaccaaatt agcgaataat tcagcattag
    20941 tataatcttc attatgtaaa acaagaaact catctaaagt aatgtgtaat ttgtctaaaa
    21001 tattgataag tcgaatacaa gatatctctg attccccacg ttcgaatcta gatatttgag
    21061 attttgaaag atgttcatct gctacagagc atagactaat ttgttttcct ttacgaactt
    21121 ttctaagtgt gatgccaagt tttgatttca taatttccca ttttcccaac aaaaattaaa
    21181 tccgttttta tttattgtac aataaataaa aacggaaagg aagtccgagt atgaagaaaa
    21241 tttcaaaatt tttgacgatt ttggttttgg tgatggatat tatcataatt gttggtgggt
    21301 aaaatgctta agtgtacact taagtcttta gaatattcta aagacttaag attttatagg
    21361 tacatagtat gaaatacaga gataaattta cataatatca atttatttta ggtacatttt
    21421 atagaataaa atacggtatt tataatttgg gaggttttaa ttgaaaaaac agaatttatt
    21481 taaaatatca aataatgtat aagagtattc aaatgctctt aatactatgg gtttaaattt
    21541 tcaaggagaa attcctgttt ttgttgacca caaaagagaa gatttacttc ataatattaa
    21601 gcgaattaac aacgaatatt ccgaatgcta taaaacaacg ccaatttacc aatttctttg
    21661 cagacgccta tttatcttga tagagaggaa gaattgaaca acaaatggct cactaagaga
    21721 atatttctca aagaaaactg atttatccaa tatctcttat gagtatttga acaagacatt
    21781 atatgataac aattacagac aacggaaatg ttggtttaca aaattgaatg ttaagtttta
    21841 atagattttt taaagtgaat atggaactta ttcttgtaat tttgctataa aatgaacaat
    21901 tttcttaata tgtaatttaa agcatagtaa gatcagaggt gaattattca caaccgaatc
    21961 gatttatgaa ggataccaat caaaattcag aagtacatgt tacaataggg acagttgctt
    22021 tatggttatt cataaacttg tgatatgttt ttcctagtga gagaaaatta ttactgtgtg
    22081 ataaaatcat gattaattga aattctagct acgtattggt atttttaata attatcagta
    22141 aattaagaat aaatcaattt gtagcaactt aaagaaagta taatatttga gctccggcag
    22201 tagctaactg tactaaatat caagtaagga ctatcaatgt taataaaccc aaattttaaa
    22261 atagaggatt taggagaaaa tcagttgttt tttatcaata aaaataaggg tacaggatac
    22321 tatgttgata atattaattt aagcgggtta agaaaacttg aagagcaagg aattttttta
    22381 caacctttga aaaaaattgg atattatata gaagaaaata tgaatattcc cattgcaaag
    22441 ttaagttgga ctaataacct ttaccctaat tgtaatttat ccagtaatac cgttttttat
    22501 tt
//
