LOCUS       NZ_LT575476.1          21605 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LT575476.1 Paenibacillus tuaregi strain Marseille-P2472T, whole
            genome shotgun sequence.
ACCESSION   NZ_LT575476
VERSION     NZ_LT575476.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:26:22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 4037316
            Orig. end    :: 4058921
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21605
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[4047316:4048921](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11605)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..21605
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21605
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="10"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             1695..2582
                     /locus_tag="ctg4_3600"
                     /transl_table=11
                     /translation="MNLKQLEQIHTGQGFIAALDQSGGSTPKALEHYGIKPESYDSEEV
                     MFGLVHEMRTRIIKSPSFDSQYILGAILFENTMDRLIDGKYTADYLWEKKGIVPFLKID
                     KGLADPEEGVQLMKPNPGLDDLLKRAVERNIFGTKMRSVIKEANPAGIRKVVEQQFAVG
                     KQIVEAGLVPIIEPEVDIHSADKLKSEQLLKEEIKTHLSKLDDKTKIMLKLSIPTEDNF
                     YSDLMKDPHVIRIVALSGGYSQSEANEKLARNHGLIASFSRALAEGLTAGQTDEEFNQT
                     LSSSIKAIYEASIK"
     PFAM_domain     1722..2330
                     /aSDomain="Glycolytic"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00274.21"
                     /description="Fructose-bisphosphate aldolase class-I"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_3600_0319"
                     /evalue="9.40E-11"
                     /label="ctg4_3600"
                     /locus_tag="ctg4_3600"
                     /protein_end="212"
                     /protein_start="9"
                     /score="41.1"
                     /tool="antismash"
                     /translation="HTGQGFIAALDQSGGSTPKALEHYGIKPESYDSEEVMFGLVHEMR
                     TRIIKSPSFDSQYILGAILFENTMDRLIDGKYTADYLWEKKGIVPFLKIDKGLADPEEG
                     VQLMKPNPGLDDLLKRAVERNIFGTKMRSVIKEANPAGIRKVVEQQFAVGKQIVEAGLV
                     PIIEPEVDIHSADKLKSEQLLKEEIKTHLSKLDDKTKIML"
     CDS             complement(2993..4228)
                     /locus_tag="ctg4_3601"
                     /transl_table=11
                     /translation="MIPLIQFELRKMVRRKATFAGMAIIVIISILLTLSTVSGESRTDQ
                     NGQEITGLSAVSLAREQTHEQAGRLTTKKIGAAIERYHAARNNPQNLNGEELSDKAYGQ
                     TEQKDAEILSLIRQIYSPKAGYDYYVINKLTSADASHFYQKRMDKVQEYLDTDYTYGNY
                     SVEDKAIFVKMNQKIAVPFAFDYTDGWKNVLLNLWIIIFAAAFIICVCVSPVFSGEYQS
                     GADSIILSSRYGRSKVIRAKFWASIILTTGLFLASILIFTLLILAIYGYFGWNSNLQII
                     QFRAPFPLTLMETYIWSVLLGFLACLLMMTFTLVLSAKMKAPFYVIICSAIVLLGPMFI
                     PYSKSSRFFNHIINLFPVKMMNGYSSFSHYELYHVLGYSIPEPYAMAGTAVILSIVLLP
                     LAYKGFRNHQVA"
     PFAM_domain     complement(3008..4219)
                     /aSDomain="ABC2_membrane_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12679.9"
                     /description="ABC-2 family transporter protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_3601_0320"
                     /evalue="6.30E-12"
                     /label="ctg4_3601"
                     /locus_tag="ctg4_3601"
                     /protein_end="407"
                     /protein_start="3"
                     /score="45.4"
                     /tool="antismash"
                     /translation="LIQFELRKMVRRKATFAGMAIIVIISILLTLSTVSGESRTDQNGQ
                     EITGLSAVSLAREQTHEQAGRLTTKKIGAAIERYHAARNNPQNLNGEELSDKAYGQTEQ
                     KDAEILSLIRQIYSPKAGYDYYVINKLTSADASHFYQKRMDKVQEYLDTDYTYGNYSVE
                     DKAIFVKMNQKIAVPFAFDYTDGWKNVLLNLWIIIFAAAFIICVCVSPVFSGEYQSGAD
                     SIILSSRYGRSKVIRAKFWASIILTTGLFLASILIFTLLILAIYGYFGWNSNLQIIQFR
                     APFPLTLMETYIWSVLLGFLACLLMMTFTLVLSAKMKAPFYVIICSAIVLLGPMFIPYS
                     KSSRFFNHIINLFPVKMMNGYSSFSHYELYHVLGYSIPEPYAMAGTAVILSIVLLPLAY
                     KGFRN"
     CDS             complement(4225..5121)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 194.7; E-value:
                     3.2e-59)"
                     /gene_kind="transport"
                     /locus_tag="ctg4_3602"
                     /transl_table=11
                     /translation="MKLELNKLTKRFSAKTAVEDMNITINSGVYGLLGANGAGKTTLMR
                     MICGVLAPSSGSITLNGADIAEMGEQYRDLLGYLPQNFGYYPDFTAEEFLLYVAALKGI
                     PPRNAKLKANDLLQTVALSDVARKKIRTFSGGMKQRLGIAQSMLNDPRIVVLDEPTAGL
                     DPKERVRFRNLISDLAKDKIIILSTHIVSDVEYIADQILVMKKGRLLMTGTVEELTSSM
                     ENCVWNCLVPAREADSWNDKYCISNLKHEGNHLELRIVSKERPLPDAVPVAPTLEDLYL
                     YYFQDESPAKPLKGVSL"
     PFAM_domain     complement(4639..5067)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_3602_0321"
                     /evalue="1.60E-29"
                     /label="ctg4_3602"
                     /locus_tag="ctg4_3602"
                     /protein_end="161"
                     /protein_start="18"
                     /score="103.3"
                     /tool="antismash"
                     /translation="EDMNITINSGVYGLLGANGAGKTTLMRMICGVLAPSSGSITLNGA
                     DIAEMGEQYRDLLGYLPQNFGYYPDFTAEEFLLYVAALKGIPPRNAKLKANDLLQTVAL
                     SDVARKKIRTFSGGMKQRLGIAQSMLNDPRIVVLDEPTA"
     CDS             complement(5153..5848)
                     /locus_tag="ctg4_3603"
                     /transl_table=11
                     /translation="LQSKQIMHTHQPGLHIRTKYIDFVIMQLRFIRAKVWAAHLMVVLV
                     TVLATQNFLLFSTLNHLQVLGMVSALTPLLALASAKVLAGSFQHGVVELEVSTKYSLDK
                     LLLARMGILGIVDAVFLTIMLSFLSHRFDPEFYVILLYLLVPFVMGLLGCLWIINHTRS
                     RESGILLYIGLLMLTQITLSFQYDALYAASATGVWIFVLVVSFIGLIWEAHTMLASCRN
                     RNVFNLIYS"
     CDS             complement(5874..6458)
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 81.3;
                     E-value: 1.1e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_3604"
                     /transl_table=11
                     /translation="MEDAELILRIQSGETEYMDCLISRHYDSIGKYCFWKTRSVEAAED
                     ITQETFYRFFRYFDQYTHVGKCRAYLYTIARRLCSEYFSIQQSVSLEELTETSGFTLSM
                     EEEVESEHSVNQLISKLPPDQQEVMLLRFIHDFKYRDIASITGLSIYMVQYKVKKSLSF
                     IKKDIERGSLLEQTPDKHHTRPSAATSFTPY"
     aSDomain        complement(5961..6398)
                     /aSDomain="TIGR02937"
                     /aSTool="tigrfam"
                     /description="sigma70-ECF: RNA polymerase sigma factor,
                     sigma-70 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_3604_0044"
                     /evalue="7.50E-22"
                     /identifier="TIGR02937"
                     /label="ctg4_3604"
                     /locus_tag="ctg4_3604"
                     /protein_end="166"
                     /protein_start="20"
                     /score="75.7"
                     /tool="antismash"
                     /translation="LISRHYDSIGKYCFWKTRSVEAAEDITQETFYRFFRYFDQYTHVG
                     KCRAYLYTIARRLCSEYFSIQQSVSLEELTETSGFTLSMEEEVESEHSVNQLISKLPPD
                     QQEVMLLRFIHDFKYRDIASITGLSIYMVQYKVKKSLSFIKK"
     PFAM_domain     complement(5976..6116)
                     /aSDomain="Sigma70_r4_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08281.14"
                     /description="Sigma-70, region 4"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_3604_0323"
                     /evalue="1.50E-10"
                     /label="ctg4_3604"
                     /locus_tag="ctg4_3604"
                     /protein_end="161"
                     /protein_start="114"
                     /score="40.6"
                     /tool="antismash"
                     /translation="NQLISKLPPDQQEVMLLRFIHDFKYRDIASITGLSIYMVQYKVKK
                     SL"
     PFAM_domain     complement(6207..6398)
                     /aSDomain="Sigma70_r2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04542.16"
                     /description="Sigma-70 region 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_3604_0322"
                     /evalue="6.90E-10"
                     /label="ctg4_3604"
                     /locus_tag="ctg4_3604"
                     /protein_end="84"
                     /protein_start="20"
                     /score="38.7"
                     /tool="antismash"
                     /translation="LISRHYDSIGKYCFWKTRSVEAAEDITQETFYRFFRYFDQYTHVG
                     KCRAYLYTIARRLCSEYFS"
     CDS             complement(6554..8365)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 162.1; E-value:
                     3e-49)"
                     /gene_kind="transport"
                     /locus_tag="ctg4_3605"
                     /transl_table=11
                     /translation="MILKFKKTKDLLLILIKTIHLLWRTSPSKLILIIIIDTLSGAIIP
                     IGLWVWKEFIDAVTNILIKGVSIKDSLMYVWLALHFVLILLNSITLTLSNYIQNIYSSM
                     LNKVISKNILEKVSLLDLKDFDNANIYNQIQKSNDESLTRSISLLRTLVGFIKNLTSFV
                     GIVGILLYFNTGIVLLCVLSALPMFYISLKILNKWFEVFNTRFENNRFVRHLKTLAITN
                     QNIKELKIYNANLFLLQTIMNILDDYLKEDKKIRRRFLIETSIMEIIDKGVVYFIKILV
                     VLISVKSKLSIGSLTMYLTSVDNLKDSISNLLSLVSTAYEDCLYVQNIFVLLDLPVQDQ
                     NEKPDFPSDFHCIQFRNVSFIYPGTDQYVLKNLDLSLYSSQSYVLVGQNGSGKTTLIKL
                     LLNLYQPTEGEILVDGVNINAFNQGTLFANISAVFQDFIKYPFDVKTNIGLGDLERLSD
                     LDQIKTAAEQSGASQFITKLPFGYDTKLQKEWSGSVDLSLGQWQKLAITRALMKPAPIL
                     VLDEPTASLDAIAEYEIYQNFREMREDRLCIMVSHRFVNTLFADSIIVLQAGELVEMGS
                     HRDLMIQNGIYANLYKLQAESYEKVPS"
     PFAM_domain     complement(6794..7258)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_3605_0325"
                     /evalue="8.90E-28"
                     /label="ctg4_3605"
                     /locus_tag="ctg4_3605"
                     /protein_end="524"
                     /protein_start="369"
                     /score="97.6"
                     /tool="antismash"
                     /translation="LKNLDLSLYSSQSYVLVGQNGSGKTTLIKLLLNLYQPTEGEILVD
                     GVNINAFNQGTLFANISAVFQDFIKYPFDVKTNIGLGDLERLSDLDQIKTAAEQSGASQ
                     FITKLPFGYDTKLQKEWSGSVDLSLGQWQKLAITRALMKPAPILVLDEPTA"
     PFAM_domain     complement(7466..8278)
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_3605_0324"
                     /evalue="2.70E-08"
                     /label="ctg4_3605"
                     /locus_tag="ctg4_3605"
                     /protein_end="300"
                     /protein_start="29"
                     /score="33.9"
                     /tool="antismash"
                     /translation="LILIIIIDTLSGAIIPIGLWVWKEFIDAVTNILIKGVSIKDSLMY
                     VWLALHFVLILLNSITLTLSNYIQNIYSSMLNKVISKNILEKVSLLDLKDFDNANIYNQ
                     IQKSNDESLTRSISLLRTLVGFIKNLTSFVGIVGILLYFNTGIVLLCVLSALPMFYISL
                     KILNKWFEVFNTRFENNRFVRHLKTLAITNQNIKELKIYNANLFLLQTIMNILDDYLKE
                     DKKIRRRFLIETSIMEIIDKGVVYFIKILVVLISVKSKLSIGSLTMYLT"
     CDS             complement(8382..9617)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_3606"
                     /sec_met_domain="Peptidase_M16 (E-value: 5.2e-12, bitscore:
                     44.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPNITHFEQNQGLYVVEGPFDGTLLSICIKAGCEAEPEGKNGLAH
                     LVEHICLAYRNHDPILEKYNSEYKQLGFHFSGYTNYGLTVLNISFPSSAECLNCCVHLI
                     KEILQASIVNEDTFQISKKEILAECNILSERWRVQKEIINYITNGQINILPVGDKDQIE
                     QLTEEDVRSFINKFYILTNMAFIIQTSLSLQTVKNAVLGILFNNNEPLPKISAKEIAYL
                     VNQPAEFYYLKSMNNIKKIELFFHKPYTHIDLKVKIVRMLFEIMLTDCIAKYLSYFKSI
                     TDIQHITISDRHITNYYYYHVISLYLQKGDCDMGTLMNELIDHLRSYFFTVNDFEEAKR
                     SISTLSMQSSDLSMEHIFDNLSANFFYDEPMHITADHFEEILNILGDLKSDDVNIYKNL
                     VLSAPCKVVIEN"
     PFAM_domain     complement(9198..9545)
                     /aSDomain="Peptidase_M16"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00675.22"
                     /description="Insulinase (Peptidase family M16)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_3606_0326"
                     /evalue="2.40E-11"
                     /label="ctg4_3606"
                     /locus_tag="ctg4_3606"
                     /protein_end="140"
                     /protein_start="24"
                     /score="43.9"
                     /tool="antismash"
                     /translation="LSICIKAGCEAEPEGKNGLAHLVEHICLAYRNHDPILEKYNSEYK
                     QLGFHFSGYTNYGLTVLNISFPSSAECLNCCVHLIKEILQASIVNEDTFQISKKEILAE
                     CNILSERWRVQK"
     CDS             complement(9718..9924)
                     /locus_tag="ctg4_3607"
                     /transl_table=11
                     /translation="MKVVNPLFRKQNNADTSAHACNCVCSVTQGNHDSTHNDSWWFWNS
                     SCGCGCDGTSANKNANHDKAVNM"
     CDS             complement(10001..11605)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_3608"
                     /sec_met_domain="PF04055 (E-value: 2.9e-15, bitscore: 55.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 4.7e-07, bitscore: 28.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     1.3e-09, bitscore: 36.4, seeds: 13, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSYIPKNEVKVMSSLFKTHDEMTRLFTLKLHNKLDRMGKLFTTD
                     LNNYFYDTGTGKVLVLDDDSFKIMNALFNLKDMLSVEQMVMEEIVSRDKIIDFENTVRA
                     EHLFLAPELDRLYSYDHYEGLKDRINEGLEQIILELTGRCNLRCGYCIYNDDCDLNRNF
                     HQDDMSLEIAKAAVEYTAKHSREEVAVTFYGGEPLLKFDLLKWAIEYSRQIMQDKKLTF
                     SLTTNMTLVTKEIAEYFASVPNLSLVCSMDGPEYVQDSYRKYANGKGSFSRAFQGLKLL
                     AEAFSASQNVLSINAVFAPPYTYDKLNDINSFFADLDFLPKHTEITIGYASKGSVEEDE
                     YITELHQNPKYSHNNENIVSPLWIWMKKQVESHSAIRSDKNNVYSSSIERTLNRVENRF
                     LTDEPRNIFPFNGCCVPGARRLYVSTTGELFVCERVGNSPSIGHVFTGINFDNIQKYYV
                     QDYSDGSIEQCKNCWAVRLCNTCYAANFTQEGFDSKNKNMKCEALRHSLLSELALYHSI
                     REITPEKLNFLEDIEVY"
     PFAM_domain     complement(10679..11188)
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_3608_0327"
                     /evalue="1.30E-14"
                     /label="ctg4_3608"
                     /locus_tag="ctg4_3608"
                     /protein_end="309"
                     /protein_start="139"
                     /score="55.0"
                     /tool="antismash"
                     /translation="LTGRCNLRCGYCIYNDDCDLNRNFHQDDMSLEIAKAAVEYTAKHS
                     REEVAVTFYGGEPLLKFDLLKWAIEYSRQIMQDKKLTFSLTTNMTLVTKEIAEYFASVP
                     NLSLVCSMDGPEYVQDSYRKYANGKGSFSRAFQGLKLLAEAFSASQNVLSINAVFAPPY
                     TYDKLND"
     CDS             11873..12625
                     /locus_tag="ctg4_3609"
                     /transl_table=11
                     /translation="VFRVGVCIDETNSRKQLEQFLIKLSKTTSYSFEIKLFSSGESLIK
                     YYRDHGSYAFHILILGIVLEGMSGIETARYIRLIPDRDVQIIFFTSHPEYMLESFEVQP
                     FQFLLKPISYDTFKSNMLSICNYIISSVNRFLTVKTEEGQTVIKTSDIIALIKIKQTLT
                     QNKIKVITSDQQYIISGTLHEYLKKLSYPFLLIHRSVIINLEHVHRFNASYVVMSNNDQ
                     MPITRAYVKQLKNIYALYMLNHFREYSK"
     PFAM_domain     11897..12220
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_3609_0328"
                     /evalue="5.70E-10"
                     /label="ctg4_3609"
                     /locus_tag="ctg4_3609"
                     /protein_end="116"
                     /protein_start="8"
                     /score="39.4"
                     /tool="antismash"
                     /translation="DETNSRKQLEQFLIKLSKTTSYSFEIKLFSSGESLIKYYRDHGSY
                     AFHILILGIVLEGMSGIETARYIRLIPDRDVQIIFFTSHPEYMLESFEVQPFQFLLKPI
                     SYDT"
     PFAM_domain     12305..12580
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_3609_0329"
                     /evalue="1.30E-14"
                     /label="ctg4_3609"
                     /locus_tag="ctg4_3609"
                     /protein_end="236"
                     /protein_start="144"
                     /score="54.2"
                     /tool="antismash"
                     /translation="TVIKTSDIIALIKIKQTLTQNKIKVITSDQQYIISGTLHEYLKKL
                     SYPFLLIHRSVIINLEHVHRFNASYVVMSNNDQMPITRAYVKQLKNI"
     CDS             complement(12832..13842)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053:beta-lactamase (Score: 86.3; E-value: 3.6e-26)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_3610"
                     /transl_table=11
                     /translation="MQKTAEWQAEDPAALGMDAGKLSELGSEIISGYSNINGIVVARNG
                     SIAYEQYFNGYGPDDVHHVASVTKSAISALIGIAINEGHIQSVDQKVLDFFPDYVLDAA
                     DTQKGDITIRHLLTMTAPYPFPDWQEPLDKMCMQPDWEKYILDMLGQNGSIGAFKYSTA
                     GAHLLSIILTRSTGQNARAFAGERLFKPTGMRVIPDYGMDSFGFEELFGSKVRGWVQDP
                     AGNSTGGWGLTMSPRDMARFGQLYLNRGKWGDRQVIPETWTVESTVLNPYGYGYLWWVR
                     EEDGVFAYSAMGDGGNAICCIPEKDMVVAIASAFMPNARDRWTLIKEHILPAVLD"
     PFAM_domain     complement(12868..13728)
                     /aSDomain="Beta-lactamase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00144.26"
                     /description="Beta-lactamase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_3610_0330"
                     /evalue="1.80E-31"
                     /label="ctg4_3610"
                     /locus_tag="ctg4_3610"
                     /protein_end="325"
                     /protein_start="38"
                     /score="109.7"
                     /tool="antismash"
                     /translation="IVVARNGSIAYEQYFNGYGPDDVHHVASVTKSAISALIGIAINEG
                     HIQSVDQKVLDFFPDYVLDAADTQKGDITIRHLLTMTAPYPFPDWQEPLDKMCMQPDWE
                     KYILDMLGQNGSIGAFKYSTAGAHLLSIILTRSTGQNARAFAGERLFKPTGMRVIPDYG
                     MDSFGFEELFGSKVRGWVQDPAGNSTGGWGLTMSPRDMARFGQLYLNRGKWGDRQVIPE
                     TWTVESTVLNPYGYGYLWWVREEDGVFAYSAMGDGGNAICCIPEKDMVVAIASAFMPNA
                     RDRWTL"
     CDS             complement(14054..14878)
                     /gene_functions="regulatory (smcogs)
                     SMCOG1171:transcriptional regulator, MerR family (Score:
                     81.4; E-value: 1.8e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_3611"
                     /transl_table=11
                     /translation="LLSIGEFSKMCGVSTKTLRYYDEIELIKPDEINPENGYRYYSIKQ
                     LKKMLLINRLKSYHFSLEEMRDMLEWEEDLSEEKLCSALLRKRLEIQEKMNALECTLKQ
                     INSDILNLEQGIPMMSYMESIEVQLVETQPMNILYLRQMLSMEDYAAGYETYFGKLYEK
                     IAVGNLTMLGTPMTIYHSPEYNPAGNDTEFAIPVKEIVKGTRDLPGGLCAKSVLKGSYS
                     ELTSVFAKLREWIEQEGYELIRSPFEIYINDPHENTVPEDSITEVYFPIRKK"
     PFAM_domain     complement(14063..14503)
                     /aSDomain="GyrI-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06445.17"
                     /description="GyrI-like small molecule binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_3611_0332"
                     /evalue="2.30E-15"
                     /label="ctg4_3611"
                     /locus_tag="ctg4_3611"
                     /protein_end="272"
                     /protein_start="125"
                     /score="57.3"
                     /tool="antismash"
                     /translation="EVQLVETQPMNILYLRQMLSMEDYAAGYETYFGKLYEKIAVGNLT
                     MLGTPMTIYHSPEYNPAGNDTEFAIPVKEIVKGTRDLPGGLCAKSVLKGSYSELTSVFA
                     KLREWIEQEGYELIRSPFEIYINDPHENTVPEDSITEVYFPIR"
     PFAM_domain     complement(14669..14872)
                     /aSDomain="MerR_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13411.8"
                     /description="MerR HTH family regulatory protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_3611_0331"
                     /evalue="3.80E-15"
                     /label="ctg4_3611"
                     /locus_tag="ctg4_3611"
                     /protein_end="70"
                     /protein_start="2"
                     /score="55.8"
                     /tool="antismash"
                     /translation="SIGEFSKMCGVSTKTLRYYDEIELIKPDEINPENGYRYYSIKQLK
                     KMLLINRLKSYHFSLEEMRDMLE"
     CDS             15316..16704
                     /gene_functions="resistance (resist) tet_MFS_efflux (Score:
                     213.7; E-value: 2.4e-65)"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 193.3; E-value:
                     8.9e-59)"
                     /gene_kind="transport"
                     /locus_tag="ctg4_3612"
                     /transl_table=11
                     /translation="LSKKVTAGIPKSVAWLSFLAFFSVLNETVFNVALPDMAVQFGISP
                     SAANWINTSFILSFAIGTAVYGKLSDLYGVRRLLLTGVLMYGVGSLVGVLFHSSYAAVL
                     IARFIQGAGISSVPALIMVIVAGSIPPKQQGRAFGLIGSVVACGESIGPVIGGVVTHYL
                     HWFYLFALPMLTLLALPFFIRDLPGEPAKKGKLDLPGAVLMSAGIVTFTLFISLYDWMY
                     LLTSLLLFLGFAWRIRKARQPFIEPSLFSRKAFILGVLTGSILLGLTAGYVSMVPYMMR
                     TVHNLPTDLIGIGVLFPGTVSVVLFGILGGMLVDKRGNLFTMRIGIILLILSLLGTALF
                     VELTPWLITGTLILTFGGLSFIKTVISTSVAGALRPEESGSGMGLLNFACFLGEGFGVA
                     VVGGIMSRSWLVSPHLPGIGSSTAGLYSNLTLILIAAALIAGTVFLLVYKRVQHAPGSA
                     SKSE"
     PFAM_domain     15361..16506
                     /aSDomain="MFS_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07690.18"
                     /description="Major Facilitator Superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_3612_0333"
                     /evalue="5.80E-48"
                     /label="ctg4_3612"
                     /locus_tag="ctg4_3612"
                     /protein_end="397"
                     /protein_start="15"
                     /score="163.7"
                     /tool="antismash"
                     /translation="LSFLAFFSVLNETVFNVALPDMAVQFGISPSAANWINTSFILSFA
                     IGTAVYGKLSDLYGVRRLLLTGVLMYGVGSLVGVLFHSSYAAVLIARFIQGAGISSVPA
                     LIMVIVAGSIPPKQQGRAFGLIGSVVACGESIGPVIGGVVTHYLHWFYLFALPMLTLLA
                     LPFFIRDLPGEPAKKGKLDLPGAVLMSAGIVTFTLFISLYDWMYLLTSLLLFLGFAWRI
                     RKARQPFIEPSLFSRKAFILGVLTGSILLGLTAGYVSMVPYMMRTVHNLPTDLIGIGVL
                     FPGTVSVVLFGILGGMLVDKRGNLFTMRIGIILLILSLLGTALFVELTPWLITGTLILT
                     FGGLSFIKTVISTSVAGALRPEESGSGMGLLNFACFLGEGFG"
     CDS             complement(16628..16804)
                     /locus_tag="ctg4_3613"
                     /transl_table=11
                     /translation="MIREQGIRPVMDQIVEDNSSPVHGKSTGLLLFSFIQIWKLNRVHA
                     EPVCTRAERQFPL"
     CDS             complement(16782..17138)
                     /locus_tag="ctg4_3614"
                     /transl_table=11
                     /translation="MRYMMVVLLEFYPSWLALPREERREHAASLQEIISRYTEHVQVRF
                     FDAEALPGKDYTDFVVCETEDLRQYHYMWEEIRDSEPYTRGYMKIKDVLMGMENAFKSY
                     ESEVLKMDDKRAGN"
     PFAM_domain     complement(16833..17120)
                     /aSDomain="Darcynin"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17074.7"
                     /description="Darcynin, domain of unknown function"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_3614_0334"
                     /evalue="1.10E-12"
                     /label="ctg4_3614"
                     /locus_tag="ctg4_3614"
                     /protein_end="102"
                     /protein_start="6"
                     /score="48.4"
                     /tool="antismash"
                     /translation="VLLEFYPSWLALPREERREHAASLQEIISRYTEHVQVRFFDAEAL
                     PGKDYTDFVVCETEDLRQYHYMWEEIRDSEPYTRGYMKIKDVLMGMENAFK"
     CDS             complement(17214..17795)
                     /gene_functions="regulatory (smcogs)
                     SMCOG1133:Transcription regulator, crp (Score: 73.7;
                     E-value: 2.1e-22)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_3615"
                     /transl_table=11
                     /translation="MDTNYESLRDLACKAMVSDEEWKLFAERSRVREVRKGTCLVETGE
                     MVMYAYYCASGLFRLFYPLPDGKEYNVAFTLENDFATSYGAMVKRMPSSYTIEALEDSV
                     VIEISYESLQEIMDSCHSWERFVRKSVERLYIRKEERERELLFLSALQRYEAFLVKYPG
                     LENRIPQYHVASYLGISPVSLSRMLRAKRA"
     PFAM_domain     complement(17439..17702)
                     /aSDomain="cNMP_binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00027.31"
                     /description="Cyclic nucleotide-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_3615_0335"
                     /evalue="1.30E-11"
                     /label="ctg4_3615"
                     /locus_tag="ctg4_3615"
                     /protein_end="119"
                     /protein_start="31"
                     /score="44.5"
                     /tool="antismash"
                     /translation="REVRKGTCLVETGEMVMYAYYCASGLFRLFYPLPDGKEYNVAFTL
                     ENDFATSYGAMVKRMPSSYTIEALEDSVVIEISYESLQEIMDS"
     CDS             complement(17839..19701)
                     /locus_tag="ctg4_3616"
                     /transl_table=11
                     /translation="MISQLLVSSIEHAVEHVCDELGVNGKNGVNLGVEQPDLLEHGDYS
                     TNVAMQLARVLRKPPIQIAAMLKTKMEQDNRMGDLISKIEIAQPGFINMHIDWKEWSQR
                     KFEMPLNKGDKVVIEHTSINPNKSAHIGHLRNSCIGDALVRLLTRAGYNVEVHNYIDDL
                     GNQLADTVVGLLNIPHKEEHTRFGDFCWDIYSRVNKEYECNPSLLEQRIKVLHSMEEGG
                     DNLAWVGALAAERIVREHLDEMNGFGINYDLLVWESSIVREGFWASAFNLLKETEQFHQ
                     ETSGKLEGCWVLKQSTANSEGQESEHSPDKVLVRSNGILTYTAKDIAYHLWKFGLLEQD
                     FLYKRFSEGLWTTNVSGSPSSFGRADLVINVIDHRQEYPQAMVKQALEILGYTDQANKL
                     RHVSYGVVSLSPGAARELGIDTSDGKTSYAMSGRQGIGIKISELLDLMEGIIEDRRPDK
                     AGLSSRMIAAAAIRYYLLRFGLLTEVVFDIKQATEVTGNTGVYLMYSFARAVSILDKAE
                     AEADIRPEAAELKFELEIAEHALLRHIAAWQDTLFTACNELTPNTICNYAYELATLFNN
                     FYAACPILKADDDTKALRLWLTLKFKETLGDALTVLGLPTPSRM"
     PFAM_domain     complement(17842..18198)
                     /aSDomain="DALR_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05746.17"
                     /description="DALR anticodon binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_3616_0338"
                     /evalue="4.80E-25"
                     /label="ctg4_3616"
                     /locus_tag="ctg4_3616"
                     /protein_end="620"
                     /protein_start="501"
                     /score="88.1"
                     /tool="antismash"
                     /translation="LMYSFARAVSILDKAEAEADIRPEAAELKFELEIAEHALLRHIAA
                     WQDTLFTACNELTPNTICNYAYELATLFNNFYAACPILKADDDTKALRLWLTLKFKETL
                     GDALTVLGLPTPSRM"
     PFAM_domain     complement(18715..19389)
                     /aSDomain="tRNA-synt_1d"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00750.21"
                     /description="tRNA synthetases class I (R)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_3616_0337"
                     /evalue="3.90E-15"
                     /label="ctg4_3616"
                     /locus_tag="ctg4_3616"
                     /protein_end="329"
                     /protein_start="104"
                     /score="55.7"
                     /tool="antismash"
                     /translation="KFEMPLNKGDKVVIEHTSINPNKSAHIGHLRNSCIGDALVRLLTR
                     AGYNVEVHNYIDDLGNQLADTVVGLLNIPHKEEHTRFGDFCWDIYSRVNKEYECNPSLL
                     EQRIKVLHSMEEGGDNLAWVGALAAERIVREHLDEMNGFGINYDLLVWESSIVREGFWA
                     SAFNLLKETEQFHQETSGKLEGCWVLKQSTANSEGQESEHSPDKVLVRSNGILTYTAKD
                     IAY"
     PFAM_domain     complement(19417..19674)
                     /aSDomain="Arg_tRNA_synt_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03485.18"
                     /description="Arginyl tRNA synthetase N terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_3616_0336"
                     /evalue="7.10E-19"
                     /label="ctg4_3616"
                     /locus_tag="ctg4_3616"
                     /protein_end="95"
                     /protein_start="9"
                     /score="68.3"
                     /tool="antismash"
                     /translation="IEHAVEHVCDELGVNGKNGVNLGVEQPDLLEHGDYSTNVAMQLAR
                     VLRKPPIQIAAMLKTKMEQDNRMGDLISKIEIAQPGFINMH"
     CDS             complement(20136..20714)
                     /gene_functions="regulatory (smcogs) SMCOG1224:TetR family
                     transcriptional regulator (Score: 147.3; E-value: 7.8e-45)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_3617"
                     /transl_table=11
                     /translation="MQGKRGRPRNMETQSSILSASYELLLESGFGAVTVEKIAERAQVS
                     KATIYKWWPNKAAVVMDGFLSAAAARLPVPDTGSVFQDILEHATNMARFMVSREGSIFL
                     EIIGEGQVDSALAEAFRTRYIQPRRLEVRDIMTRALQRGELEKNVDIALCTDLIYGPIF
                     YRLLVTGDPINDSYVEQIVTHVFKGIQST"
     PFAM_domain     complement(20160..20495)
                     /aSDomain="TetR_C_11"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16859.7"
                     /description="Tetracyclin repressor-like, C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_3617_0340"
                     /evalue="2.90E-32"
                     /label="ctg4_3617"
                     /locus_tag="ctg4_3617"
                     /protein_end="185"
                     /protein_start="73"
                     /score="111.4"
                     /tool="antismash"
                     /translation="VPDTGSVFQDILEHATNMARFMVSREGSIFLEIIGEGQVDSALAE
                     AFRTRYIQPRRLEVRDIMTRALQRGELEKNVDIALCTDLIYGPIFYRLLVTGDPINDSY
                     VEQIVTHV"
     PFAM_domain     complement(20538..20666)
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00440.25"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_3617_0339"
                     /evalue="1.60E-12"
                     /label="ctg4_3617"
                     /locus_tag="ctg4_3617"
                     /protein_end="59"
                     /protein_start="16"
                     /score="47.1"
                     /tool="antismash"
                     /translation="ILSASYELLLESGFGAVTVEKIAERAQVSKATIYKWWPNKAAV"
ORIGIN
        1 gtcgcccgga tcgaagcgat atgaccggtc agatcgcgcc gtaccgattc ctgccggact
       61 tccttcaaga ctttctcggc agccaccagc ttgctctggg caccttgcac atctccggcc
      121 attagcagaa cagaggcata cataacccaa agagagggct gcttatccag ctcactctcc
      181 ggcagcgatt ccagccaatt tctcacagct gacgcagctc cccggaagat gattggcatt
      241 cccttaccct ccgccagccg ggctgcacga ggtatatctg ccgcggaagc ggcatgttga
      301 aatgcttcca gctcgaaccc ctgctcttca taccaagcac tggctttctg atggagctca
      361 gccaattctg ttgcagggtc cctcccgtgt tcggcaatgt gccgggacag ctgacttctg
      421 agcaaatcgg caaacatatg atggtagcga taccactgac gctcatcatc cagaggaaca
      481 agaaacaaat tggcttgttc aagataggtc aagatgtctt ggcttcccct tacaagatcg
      541 ctggacatct ggtcagttcc cgttagaatt gcgctgcaca gtgaaccgca gaaccggtcc
      601 agaatcgaag tataaagcag aaaatgccgg atatccggag cctgatattg aagcacctct
      661 tcaagcagat aatccagcac ataacggtgg ttccccgaga aggaagaaat gaatgcatcc
      721 ggatctttat gacccttaag ggataacgcg gccagttgca gcccggcgat ccacccttcg
      781 gtacgatcct taagctgtgc cacgctttca ggcggcaggc gaagccccat gacctgagcg
      841 aggaactctt ctgcttccct agtattaaaa cgcaggtccg tcccccttac ttcgttcagc
      901 tggttcctga cccgcagccg ggcaagtggc aaagccggat ccttgcggct ggcaatgacc
      961 aaatgcatgc ccgaaggcat gtgctcaagc agcagggcaa cagccttttg aaccggctcg
     1021 gcttcaatga catgataatc gtccataaca agcacaaaag aatggggaat ctcgatcagg
     1081 tcgccgatta gagcctctac catcgattcc atatacacgg cttgaggtga ctgcagcatc
     1141 agagatacct gttcgcccaa accagccgaa acagttctaa gggcagcaat aagatacatc
     1201 aaaaagcggc tcggatcgtt atcaccttca tcaagagaca gccaggcggc aggagaagcg
     1261 cagcttgcca tccactgacc gagcaatgtg gtctttccgc ttcctggccc tgccgaaatc
     1321 aaggtgagct tcccctgcat tccatcattc agctgctggg ttaagcgggg gcgctggact
     1381 actattgatc gcgctgctgg aatatttaat ttagtggaaa taatagctgc tgtcataata
     1441 ccccccagta taaaagttga ttttcaatca tttaggccat ataaatttga taactagttc
     1501 tacaatctca gcacgattcc ctttacggat caacaatcct atacgaagat aatcactcag
     1561 actaccggga aatcggtatg cagcagtttc gatacgcctg cgattggtta tatgaagcct
     1621 gaatctaacc cttggaagtt agggaattat aatagggtcg gaaatgcgtt tcgaccaaga
     1681 aaggagaact atctatgaat ttgaagcagc tggaacaaat ccatacaggc caaggattta
     1741 ttgcggcctt ggatcaaagc ggaggcagca ccccaaaggc gctggagcat tatggcatca
     1801 aacctgaaag ctatgatagc gaggaagtca tgtttggact ggttcatgaa atgcggaccc
     1861 ggatcatcaa gagcccctca tttgattccc agtacattct gggagcgatc ctgttcgaga
     1921 acacgatgga ccgcctcatc gacggcaagt ataccgcaga ttatctctgg gaaaagaaag
     1981 gcattgtgcc gtttctaaaa atcgataaag gactcgctga tcccgaagaa ggtgtacagc
     2041 tcatgaagcc taatccaggc cttgacgatc tgctgaagcg ggctgtagag cgcaacatct
     2101 tcggcaccaa gatgcgctcg gttattaagg aagcgaatcc tgccggaatc cgcaaggttg
     2161 tggagcagca gtttgccgtg ggtaaacaga ttgtggaggc aggactggtt cctattattg
     2221 aaccggaagt ggatattcac agcgcggata aactgaagtc ggagcagctt ctcaaggaag
     2281 agatcaaaac ccatctctcc aagcttgacg acaagaccaa gatcatgctt aagctgtcca
     2341 ttccaacgga agacaatttc tacagcgatt taatgaagga cccgcatgtg ataagaattg
     2401 tggctctttc aggagggtat tcccaatccg aagcgaatga gaagctcgcc cgcaatcacg
     2461 ggctgatcgc aagcttctcg cgtgccctcg ccgaggggct gacagccggc cagacggatg
     2521 aggaattcaa ccagacgctt tcaagctcca ttaaagcaat ctatgaggct tcgatcaaat
     2581 aaaagcggct gttcttgagt gaacagacag ctacttaaat taattgagca gccgatcact
     2641 cacaccaccg tacattctgt tcagtataca gtggttcaac cgtttcagga caattgtcgt
     2701 agaggctcgt actgtgcaag ggaaggatac tcccctgcct gtacgagcct ttcttttgtt
     2761 aaggagtcaa ggcagcatct ggcctattgg caacccgcca gtatcccgtc cgtgtactca
     2821 cccatggtag gcctaccact ccggtattcc aagcatccga agttttgcaa ctttgtttta
     2881 ggcttcttct accctttcca gatgtacttt cacaccgtct tcatagcctt tcattccagc
     2941 tttgcaggat taacctgctt gttaactgta cccatagtaa gtttccagac acttacgcaa
     3001 cttggtggtt cctaaaaccc ttataggcta aggggagaag tacaatggat aagatgactg
     3061 cagtgccagc catagcgtaa ggttcaggta tactgtatcc taacacatga tacagctcat
     3121 aatgggagaa cgaagagtac ccattcatca tttttacagg gaataaattg atgatatgat
     3181 tgaagaatcg gctgcttttg ctataaggaa taaacatcgg tccaagaagg acaatggcag
     3241 agcatattat gacataaaag ggggccttca ttttggcaga caacacaaga gtgaatgtca
     3301 tcatcaggag acaggccaga aaaccaagca agacagacca gatataggtc tccattaggg
     3361 ttagtggaaa gggcgcccga aactggataa tctgcagatt gctgttccaa ccgaaatatc
     3421 cgtaaatggc gagaatcagc agggtgaaaa ttagaataga ggctaaaaat aatccggttg
     3481 taaggattat actcgcccaa aacttggccc tgatgacctt gcttcgtcca taacgggagg
     3541 aaagaataat agagtcggca ccggactgat actctcccga gaagacaggt gacacacata
     3601 cacatattat aaaagcagct gcaaaaataa tgatccataa attaagcagg acgttcttcc
     3661 agccatccgt ataatcaaag gcgaaaggca cagcaatttt ttgattcatc ttcacaaaga
     3721 tcgctttgtc ttcaaccgaa taattgccgt aagtatagtc tgtgtccagg tactcctgga
     3781 ccttgtccat tctcttctga tagaaatggc tcgcgtctgc cgaagttaat ttattaataa
     3841 cgtaatagtc atatcccgcc ttgggggagt aaatttgccg gatcagactg agaatttcag
     3901 cgtccttttg ctccgtttga ccataggctt tatcagaaag ctcttcaccg ttcaaatttt
     3961 gggggttgtt ccttgcagca tgataacgtt ctatcgcggc ccctattttc ttggtagtca
     4021 gccttccggc ctgctcatgt gtctgctctc tagccagcga gactgcagaa agaccggtaa
     4081 tctcctgacc attttgatct gtacggcttt ctccggagac tgtagagaga gtaagcaata
     4141 ttgaaataat gacgattatg gccatgccgg caaaagttgc ttttcttctt accatcttgc
     4201 ggagttcaaa ttggataagc gggatcataa gctcaccccc ttgaggggct tagcaggtga
     4261 ttcatcttgg aagtaataca gatataggtc ctccaaggtg ggagcgacag gcacggcatc
     4321 tggaagcggt ctttctttgg acacaatgcg cagctccaaa tgattgccct catgcttgag
     4381 attgctgata cagtacttat cattccagct atccgcctct ctggccggta ccagacagtt
     4441 ccacacacag ttctccatag aagacgttaa ctcttcgacg gttcccgtca ttaagaggcg
     4501 ccctttcttc atcaccaaaa tttgatctgc tatatactcc acatccgata caatatgagt
     4561 ggataatata ataattttgt ccttagccag gtccgaaatc aaattgcgaa atcttactct
     4621 ttccttggga tcgaggcccg ctgtaggctc atccagtact acaatgcgtg gatcattcag
     4681 catagactgg gcaatgccca aacgctgctt cattccaccg gagaaagttc gtattttttt
     4741 gcgggctacg tcagataaag cgactgtttg cagaaggtca tttgctttta gcttggcatt
     4801 gcgcggcggt atgcctttta gtgcagcaac atacagcaag aactcctctg cagtaaagtc
     4861 aggataatat ccaaaatttt gaggcaaata accaagcaaa tcacgatatt gctctcccat
     4921 ctcggcaata tcagcgccat tcaacgttat tgaacctgat gaaggagcca gcactccgca
     4981 gatcatacgc atgagtgttg tttttccggc tccatttgca ccgagcagac cataaactcc
     5041 actatttatt gtgatgttca tgtcctccac agctgttttg gctgagaaac gcttggtcag
     5101 tttgttcagc tcaagtttca taattgagtc ctcccgtgca gctgtattca aactatgaat
     5161 aaatcagatt aaaaacattt cgatttctgc aagaagccag catcgtatga gcttcccaga
     5221 ttaagcctat gaaagaaaca acgagcacaa agatccagac acccgttgca gaggcagcat
     5281 acaaagcatc atactgaaat gacagggtta tttgtgtcag cattaacagg cctatatata
     5341 acaaaatgcc ggactctctg cttcgggtat gatttataat ccaaaggcat ccgagtaaac
     5401 ccatgacaaa tggtacaagc aggtataaca gaatgacata gaactccgga tcaaagcggt
     5461 gagaaagaaa ggaaagcatt attgtaagaa aaaccgcatc cacaatgccc aaaatgccca
     5521 tacgagctaa caggagcttg tcaagtgaat atttggtact tacttcaagc tcaaccacac
     5581 catgttggaa ggaaccggca aggaccttgg cgctggcgag agcaagaagt ggggtcaagg
     5641 cggataccat accgagcact tgcagatggt tgagtgttga gaataataaa aaattttgcg
     5701 tggccaatac ggtaaccaag acaaccataa ggtgagcagc ccataccttt gcacgaataa
     5761 aacgaagctg cataataaca aagtcaatgt actttgttcg gatatgaagt ccgggctggt
     5821 gtgtatgcat aatttgtttg gactgcaaaa tggtctcctt cagcttttcg ggatcagtag
     5881 ggggtaaagg aggttgctgc agaaggcctc gtatggtgtt tatctggcgt ttgttcaagc
     5941 aaacttcccc tttctatatc tttcttaatg aagctaaggc tttttttgac cttgtactgg
     6001 accatatata tacttaatcc ggtaattgaa gcgatatcac gatatttgaa gtcatgaatg
     6061 aaacgaagca gcatgacctc ctgctggtct ggcggcaatt tgcttatcaa ttggtttacg
     6121 ctgtgctcac tttccacctc ttcctccatg gacagagtaa acccgctggt ctccgttagc
     6181 tcctccagcg agacggactg ttgaatgctg aaatattcac tgcacaaacg gcgtgcaatg
     6241 gtgtacaagt aagcacgaca ctttcccaca tgggtgtact ggtcgaaata acgaaaaaag
     6301 cgatagaagg tttcctgggt aatgtcttcg gccgcttcaa cgcttcgggt cttccaaaag
     6361 caatatttgc ctatactgtc gtaatggcgg ctaatcagac aatccatata ttcggtctct
     6421 ccgctctgaa tccgcagtat gagttcagca tcctccatgt tgatcccccc tttctattat
     6481 gtataactgt taaaacgtcg aaaaaatgga aacctggtat gatttttttg tgaacttaaa
     6541 aagcaacccc gaattatgag ggtacttttt cgtacgactc ggcctgtaat ttatataagt
     6601 tggcatatat cccgttttgg atcattagat ctcgatgtga ccccatttct accagctcgc
     6661 cagcttgcag tacaattata gaatctgcaa agagggtatt cacaaaacga tgactaacca
     6721 ttatgcataa cctatcttcc ctcatttccc gaaaattttg gtaaatttca tattctgcga
     6781 ttgcatctaa agaagctgtt ggttcatcta aaaccaatat tggagcaggt ttcataagtg
     6841 ctcttgtaat agcgagtttc tgccattggc ctaatgacaa gtcaacactg cctgaccatt
     6901 ccttttgcaa tttggtatca taaccgaatg gcagcttagt aataaattga ctggcaccgg
     6961 attgttctgc tgccgtttta atttgatcca ggtcactcaa gcgttccagg tcgcccaatc
     7021 caatatttgt tttaacatca aacggatatt taataaaatc ttgaaacact gctgaaatat
     7081 tagcgaacaa ggtaccctgg ttaaacgcat taatatttac tccgtcaacc aatatctcac
     7141 cttctgttgg ttgatatagg tttaatagga gcttgattaa tgttgttttc ccagaaccat
     7201 tctgtcctac aagcacgtag gattgagagg agtacaagga gaggtccaag ttctttagga
     7261 cgtactgatc tgtacctgga taaataaaag aaacatttct gaactgaata caatgaaagt
     7321 cagatggaaa atcaggcttc tcattttgat cttgtactgg aaggtctaaa agtacaaaga
     7381 tattttgcac atacaaacaa tcttcataag cggttgacac taatgatagc aggttggata
     7441 ttgaatcctt caaattgtct actgaggtaa gatacatagt tagggagcct atggacaatt
     7501 ttgatttaac actaataagt actactaaaa tttttataaa ataaacaacc cccttatcaa
     7561 taatttccat aatcgaagtt tcaatcaaga aacgtcttct tatcttctta tcctctttta
     7621 agtagtcatc aagaatgttc ataatggttt gcagtaaaaa caagtttgcg ttatagattt
     7681 taagttcttt aatattttga ttggtaattg caagagtttt aaggtgtctt acaaaccgat
     7741 tattttcgaa ccgtgtatta aatacttcaa accatttatt taaaattttt aagctgatat
     7801 agaacatagg caacgctgat aacacacaga gcagcacaat cccggtatta aagtataata
     7861 aaattccgac tatccccaca aaacttgtta agttttttat aaagcccacc aatgtgcgca
     7921 gcagacttat acttctagta agagattcat cattcgactt ttgaatctgg ttatagatat
     7981 tggcattatc aaagtctttc aggtccaaca gggatacctt ttcaaggatg tttttactga
     8041 taactttatt tagcatggat gaatatatat tttgaatgta gttggagagg gtgagggtta
     8101 ttgagttaag taggattaga acaaagtgca aggccagcca gacatacatt aatgagtctt
     8161 taatgctgac ccctttgatt aatatattag taacagcatc aataaactcc ttccaaaccc
     8221 ataagcctat tggaattata gctccggata gagtatcaat tattatgatt aaaataagtt
     8281 tagaaggact agttctccaa agaagatgga tagtttttat taaaatcagg agaaggtctt
     8341 ttgtcttttt aaattttaaa atcattcact tcaccttctc cctaattttc tattactact
     8401 ttgcaaggag cacttaagac taaattttta tatatattta catcatctga ttttaaatca
     8461 cctagaatat taaggatttc ttcaaaatga tctgctgtaa tgtgcatggg ctcatcataa
     8521 aagaaattag ctgataaatt atcgaaaata tgctccatgc tcagatctga tgattgcatg
     8581 gataatgttg agatggatct ttttgcttct tcgaagtcat tgactgtgaa gaagtatgac
     8641 cttaagtggt ctataagctc attcatgagc gtgcccatgt cacaatcgcc cttttgcaag
     8701 tatagactga taacatgata ataatagtaa ttagtgatat gtctgtcaga aatggttata
     8761 tgttggatat cagtgatcga tttgaaataa gaaagatatt ttgcaataca atctgttagc
     8821 attatttcaa agagcattct gactattttt acttttaggt ctatatgggt ataaggttta
     8881 tggaagaata actctatttt tttgatgttg ttcatagact tgaggtaata aaattctgca
     8941 ggttggttaa ccaaataagc aatctctttt gctgatatct tgggaagcgg ctcattattg
     9001 ttgaaaagga tgcctagaac ggcatttttc actgtctgaa gtgacaggct ggtttggata
     9061 atgaaggcca tattggttaa aatataaaac ttgtttatga aacttcgcac atcctcttca
     9121 gttagctgct caatttgatc tttatcgcct actgggagta tatttatttg tccattcgta
     9181 atgtaattaa taatttcttt ctgaactctc catctttcac tcagaatgtt acactcggca
     9241 aggatctctt ttttagatat ttggaatgtg tcttcattca caatagatgc ttgaagaatc
     9301 tcttttatta ggtgcacaca gcaattcaag cattctgcgg aactcggaaa agatatattt
     9361 agaacggtta ggccataatt ggtataaccc gagaaatgaa accccagttg cttatattca
     9421 gagttgtatt tttctaaaat aggatcatga ttgcggtatg ctaaacaaat atgttcaacc
     9481 aagtgagcca gtccattctt tccttcaggc tctgcctcac agccagcctt gatacaaata
     9541 gagagaagag tcccatcaaa agggccttct acaacataca agccttgatt ctgctcgaag
     9601 tgtgttatat ttggcatgct aaccacccta attatgaatg ttctttcccc acaaaagaga
     9661 gctgtagtta taagaaaagg cgattcgaca tacgccaaat caccttttac ggactattta
     9721 catattcacc gctttatcat gattggcatt cttatttgca cttgttccat cacaaccaca
     9781 accacagctg ctgttccaga accaccatga atcattatga gtggagtcat gatttccttg
     9841 agttacacta caaacacagt tgcaagcatg tgcagatgta tctgcattgt tctgtttacg
     9901 aaacaatggg ttaacaactt tcataatagt gtcacctcct ttctggaaaa ttgtatatta
     9961 tccttaccag gcaaataacg cctgagaaag ggtaacacct ttaataaact tctatatcct
    10021 ctaagaagtt gagcttttct ggcgttatct ctcggataga atgataaagt gccagttcac
    10081 tcagaagtga atgtctgaga gcctcacatt tcatattttt atttttggag tcaaagcctt
    10141 cttgggtgaa attagcggca taacaagtgt tacacaatct aacagcccag cagttcttgc
    10201 attgctcaat agagccatct gaataatcct gaacataata tttctgtatg ttatcaaaat
    10261 tgatcccagt gaaaacatga ccgatagagg gtgagtttcc tacacgctcg caaacaaaca
    10321 gctccccagt cgtactcaca tacaatcttc gggcacctgg aacacaacag ccattgaagg
    10381 gaaaaatatt tctaggctca tcagttaaga atctgttttc aactctatta agagttcttt
    10441 ctatagatga ggagtacaca ttatttttat cacttcttat agctgaatga ctttctacct
    10501 gtttcttcat ccagatccat agtggactaa cgatattttc gttattgtgt gaatacttag
    10561 ggttttggtg cagctccgta atatattcat cctcttctac gcttccttta gaagcataac
    10621 caattgttat ttccgtgtgc tttggtaaaa aatcgaggtc agcaaaaaat gaattaatat
    10681 cgtttaattt atcgtaagta tagggaggag caaacacggc attaatcgac agaacatttt
    10741 gactcgctga aaaggcttcg gctagcagct ttaatccttg aaatgctctt gagaagcttc
    10801 ctttgccatt ggcatacttt ctataggagt cctgtacata ttctggacca tccatactac
    10861 atacaaggct taagttcgga actgatgcga aatattctgc tatctctttt gtaaccagcg
    10921 tcatattagt tgttaatgag aaggtcaact ttttatcctg cataatttgc ctggaatatt
    10981 cgatagccca ttttaataaa tcaaatttca acaagggctc gccgccatag aatgtaacgg
    11041 caacttcttc tctcgagtgt tttgcagtat attcaaccgc cgctttagct atttccaggc
    11101 tcatgtcgtc ttgatgaaag tttctattta aatcgcaatc atcgttataa atgcagtagc
    11161 cgcaacgaag attacaacgg ccggtcaact caagaatgat ctgttccaat ccctcattta
    11221 ttcggtcttt caatccttca taatgatcat aggaatacag cctatcaagt tcaggagcaa
    11281 gaaagagatg ctctgccctc accgtgttct cgaagtcaat aattttgtct ctgctgacta
    11341 tctcttccat aaccatctgt tcaacactga gcatatcctt caagttaaat aaagcattca
    11401 taattttgaa ggagtcgtca tcaaggacga gcactttccc tgttccagta tcatagaagt
    11461 aattattcaa atctgttgtg aatagctttc ccattctatc cagcttgtta tgaagcttga
    11521 gtgtgaataa gcgtgtcatt tcatcatgcg ttttgaatag agaactcatc accttcacct
    11581 cgttctttgg aatataactg ttcatagtac cttctttaaa accctattgt gattttcttc
    11641 acttttttat aaatcaatat gctataggtt tatgttcatc caaaatatat atcatccaac
    11701 ccaaaaatgg aataacctgt atttaaaatg taaaaaaatc tacctcaaca tacaagtctt
    11761 gtgagtatta agttagatta ttccattttt ttccaaacat taatttaact cttttgtatt
    11821 attatgggtt attaaattag atgcaaaggt tattctaagg gagggaaata tagtgtttcg
    11881 agtaggggtt tgcattgatg agactaactc acgaaagcag cttgaacaat tccttataaa
    11941 gctttccaag accacttcct attcttttga aataaaactc ttttcttcag gtgagtcctt
    12001 gattaaatat tatagggatc atgggtcata tgcctttcat atccttatcc ttgggattgt
    12061 tctggaagga atgagcggaa tagagacagc acgctacata aggcttattc cggacagaga
    12121 cgttcagatc atttttttta ctagtcatcc agaatacatg cttgaaagtt ttgaagttca
    12181 gccatttcaa tttttgctaa agccaatctc ttatgatact tttaaaagca atatgttatc
    12241 catttgcaat tatatcattt cgtcagtcaa ccgctttcta actgttaaaa ccgaggaagg
    12301 gcaaaccgtg ataaaaactt cggatattat tgctctaata aaaattaagc aaacgttaac
    12361 acaaaataaa attaaagtga ttacatcaga tcaacaatat attatttcag gcacactcca
    12421 tgaatatcta aagaagctta gttatccttt tctgcttatt catcgttcag ttattattaa
    12481 tcttgagcat gttcacaggt tcaatgcttc ttatgttgtc atgtccaata acgatcaaat
    12541 gcctattact cgggcctatg taaagcagct aaaaaacatt tatgctcttt atatgctgaa
    12601 tcactttaga gaatatagca agtaaggtaa gctagcttca ttcaacatag gaagttagtg
    12661 ggtggatgcc ttattaaatg ataagccgcc acctgtatcg tacttgctta ttgagagaag
    12721 aacaacgccc cttgtccatt tctggacttg gggcgttatt ttatatacca attgctttaa
    12781 ctccaaatac tcactggact tctcccatac ctcagaatcc cacatgccgg actagtctag
    12841 tacagctgga aggatatgct ccttaatcag agtccaccta tcacgggcat ttggcatgaa
    12901 agctgaagct atcgctacaa ccatgtcttt ctccgggata cagcaaatcg cattaccgcc
    12961 gtcccccatg gccgagtagg caaaaacacc atcctcttcc cgcacccacc acaggtatcc
    13021 atagccgtaa gggttcaaga cggtggattc aacggtccat gtctccggaa tcacctgacg
    13081 atcgccccat ttgccacggt tcagatacag ttggccaaat cgtgccatgt cccgtggact
    13141 catcgtaaga ccccatccac ccgtcgaatt tccggcgggg tcctgcaccc atcctcgaac
    13201 cttgcttccg aatagttcct cgaacccgaa agagtccatg ccataatccg gaatgactct
    13261 catgccagtt ggcttgaaca atcgttcccc cgcaaacgca cgggcgtttt ggccggtgct
    13321 gcgggtaaga atgatggaca gcagatgagc ccctgcagtg gaatatttga acgccccgat
    13381 gcttccgttt tggccaagca tatccaggat atatttctcc cagtctggct gcatgcacat
    13441 cttgtccagc ggttcctgcc aatctgggaa tggatacgga gccgtcatgg tgagaagatg
    13501 ccggatagta atatccccct tctgggtgtc cgcagcgtcc agaacatagt cagggaagaa
    13561 atccagcact ttctggtcca cggattgaat gtgcccttca ttgatcgcaa tccctatgag
    13621 agccgagatt gcgcttttgg tcacggacgc cacgtggtgc acatcatccg gaccataacc
    13681 gttaaaatat tgttcgtacg caatacttcc atttctcgct acaacaatcc cattaatatt
    13741 gctgtatccg gatataattt cagagccaag ctctgacagc ttcccggcat ccattcctaa
    13801 agcagccgga tcttcagcct gccattctgc ggttttttgc ataataaatt cctcctaaat
    13861 ctgtataagt tgaacttaag atttaccatt aagcaagagt gtgaaatgat tctgaagaag
    13921 cgaagcgttc gcctttgtga cctggcttcc accttataaa tttaatcaag aaatctgggc
    13981 gcaacagcga tcggaggaac ttttcacacg gctgcttcca tgtgtaaatc aatagttcaa
    14041 cttatctggc tttctatttt ttcctgattg gaaaatacac ctcagtaatg ctgtcctcag
    14101 gcacggtgtt ctcatgggga tcgttgatat aaatttcaaa gggggatcgg ataagctcat
    14161 agccttcctg ctcgatccac tctctcagct tggcaaatac cgaggtcagc tccgaatacg
    14221 agcctttcaa gacggacttg gcacagagcc cccccggcaa atctctcgtt cccttaacaa
    14281 tctctttgac cggtatggca aactccgtat cattgcccgc cgggttatat tcagggctgt
    14341 ggtaaatcgt catcggtgta cccagcatgg tgagattccc gacggctatc ttctcataca
    14401 atttgccaaa ataagtctca taccccgcgg catagtcttc catgctgagc atttgacgca
    14461 agtaaagaat gttcatcggc tgagtttcaa ctagctgtac ctcaatgctc tccatgtagg
    14521 acatcatcgg tatgccctgc tccaagttca agatatcgct gtttatctgc ttaagcgtgc
    14581 attctaaagc gttcatcttc tcctgaatct ccagcctctt ccgcagaagc gcggaacaca
    14641 gcttttcctc ggacagatct tcttcccact ccagcatgtc tctcatctct tccagggaga
    14701 aatggtacga tttcaagcgg ttgatcaaga gcatcttctt aagctgcttg atggagtagt
    14761 accggtaccc gttctcagga ttaatctcat ccggtttgat aagttcaatt tcatcataat
    14821 atcgaagcgt ttttgtagat acgccgcaca tcttagagaa ctccccaatt gataacaagg
    14881 ggtcacctcc tcctatttag ataatcaggt gctgtgttct cctctactta acaccttccc
    14941 ctaagggcaa agtcaacggc aaattacgag ctctatctcg acgtgaaaag ctcacccagc
    15001 gtggctgaat atgattctaa tgaggcatct ccatagtttg aataaagcat aatcattatt
    15061 ttttgaaaaa tatagactta tatctgcgag cttatatctc cagcagacaa cgtaggattt
    15121 tttataatta aattttccat tgaaattcca aactttctgg aaatatgatg ggttgaatca
    15181 ctattttgat gaacatttta atcaggaggc gttaatatga agtgcaatgt atttaagagg
    15241 gtactaaatc cggggaaaga cgtatcactg gccctataaa ctgcgtagtt ccctgttcaa
    15301 taaggggcta ttccattgag taaaaaggtt acagccggca tcccaaaatc ggttgcctgg
    15361 cttagttttc tggcgttctt cagtgttctg aacgaaacgg tatttaacgt ggcgctgccg
    15421 gatatggcag tccagttcgg gatttcgcct tcggcggcga attggatcaa cacaagcttt
    15481 atcctttcgt ttgccatcgg aactgcggtg tatggcaaat tgtcggattt gtacggtgta
    15541 agaaggcttc ttctaaccgg cgtactgatg tatggtgtag gatctttggt cggagtatta
    15601 tttcactcca gttatgctgc ggtgctgatt gcccgcttca tccaaggagc aggaatctca
    15661 tcggttccag ctctgattat ggttatcgta gccggatcaa tcccgccaaa gcagcagggc
    15721 agagccttcg gccttatcgg ctctgtggta gcctgcgggg aaagcatcgg cccggtcatc
    15781 gggggagtgg taacccatta tttgcactgg ttttacttgt tcgctctgcc gatgcttacc
    15841 ctgctggcct tgcctttttt tatacgggat ctgccgggag aacccgcgaa gaagggaaag
    15901 ctcgaccttc cgggcgctgt actaatgtct gcggggattg taacatttac tttgttcatt
    15961 tcactgtacg actggatgta cctgctaacc agcctgctgc tgttcctcgg gttcgcctgg
    16021 cgtattcgta aggctcgcca gccttttatc gaaccttctt tatttagcag aaaagcattt
    16081 atcctcggcg tattaacagg cagtattctg ttaggcctga ctgccggcta tgtatccatg
    16141 gtgccttata tgatgagaac cgtgcacaac ctgcctacag acctcatcgg gatcggcgtt
    16201 ctgtttccgg gcacggtcag tgtggttctc tttgggattc taggtggaat gttggttgat
    16261 aaacgcggaa atttgtttac catgcgtatc ggcataatat tgctcatcct aagtttgtta
    16321 ggtacggcat tatttgtcga gctgacgcct tggcttatca caggcaccct gatcctgacc
    16381 ttcggcggtc tgtcctttat aaagactgtc atctccacca gtgtagcagg tgcattgcgt
    16441 cctgaggaat ccggatcggg catgggcctg ctgaactttg cctgcttcct gggagaaggc
    16501 tttggtgtgg ctgtagtagg aggcataatg tccagatctt ggctcgtatc tccgcatctt
    16561 ccggggattg gcagcagcac ggcaggcctg tacagcaatt tgacactcat tctgattgct
    16621 gccgccctta tagcgggaac tgtctttctg ctcgtgtaca aacgggttca gcatgcaccc
    16681 ggttcagctt ccaaatctga ataaatgaaa acaacagcag ccccgtgctc ttcccatgca
    16741 cggggctgct gttgtcttcc acgatctgat ccattaccgg cctaattccc tgctctctta
    16801 tcatccattt taagaacctc ggattcatag gacttgaagg cgttctccat ccccatcaga
    16861 acatccttga tcttcatata acctcgggta tacggctctg aatccctaat ttcctcccac
    16921 atatagtggt actggcgcaa gtcttcggtc tcacatacta caaaatccgt ataatccttg
    16981 cccggcaagg cttccgcatc gaaaaaacgc acctgcacat gttcggtgta cctgcttatt
    17041 atttcctgca gtgaagcagc atgttccctc cgttcttccc ggggcagggc cagccaggaa
    17101 gggtaaaatt ccaacaaaac aaccatcata taacgcatat tcctcaacct ccatcaacta
    17161 agcagctatg aggatattgt aatgcagggc atccgaatcc gcattaacat aggttaagcc
    17221 cgttttgcac gcagcatccg gcttagcgag actggagata tgcccaaata agaggcaaca
    17281 tgatattgag gaattctgtt ctccagtccg gggtacttaa ccaggaacgc ctcatatctt
    17341 tgaagtgcgg acaggaacaa tagttcacgt tcacgttctt cttttcggat atacaagcgc
    17401 tccacactct tgcggacaaa tctctcccag ctatggcagc tgtccataat ttcctgtaag
    17461 gactcatatg aaatctcaat aactacagaa tcctccagag cttcaatggt gtaggaggat
    17521 ggcattcgct tcaccatagc cccataagag gtggcaaaat cattttccaa agtaaaagct
    17581 acattatact ccttgccatc cggcaggggg tagaacaaac ggaataaacc ggaagcacag
    17641 taataggcat acatcaccat ctcaccggtt tccaccagac aagtcccctt ccggacctcc
    17701 cttacacgcg aacgctcggc aaacaatttc cactcttcat ccgagaccat agccttgcaa
    17761 gccagatccc ttaacgattc ataatttgtg tccataaccg tacctcaatg cgaaagttaa
    17821 ctctataata acactccctt acatacggct tggcgttgga agtccaagta cggtaagtgc
    17881 atctccgaga gtttccttga attttagcgt aagccaaagt cgaagcgctt ttgtgtcatc
    17941 atcagctttc agaatcggac atgcggcata gaagttattg aacaaagtgg ccagctcata
    18001 tgcataatta catattgtat tgggagtcag ttcattgcag gctgtgaaca gggtgtcctg
    18061 ccaagctgcg atatgtctga gcaacgcatg ttcggctatt tccagctcaa acttcaattc
    18121 cgctgcttct ggccttatat ccgcctcagc ctcggctttg tccaagatac tcactgcacg
    18181 ggcaaaagaa tacatcaaat atactccagt attgcctgtc acttcagttg cttgtttgat
    18241 gtcaaagacg acttctgtta ataacccgaa cctcagaagg taataccgaa tggcagcagc
    18301 ggcaatcatt ctgctggata ggccggcttt atccgggcgt ctatcttcga taattccctc
    18361 cataagatca agcagctcgg aaattttgat cccgattcct tgtctaccag acatggcata
    18421 tgacgtcttg ccgtccgatg tgtctatgcc tagctcccgc gctgctccag gacttaatga
    18481 aaccacccca taactgacat gacgaagctt gttagcttga tcggtatatc ctagaatttc
    18541 aagagcttgt ttgaccatgg cttgtggata ctcctgcctg tggtcgatga cattgataac
    18601 aagatctgcc ctgccgaagg atgatgggct tccactcaca tttgtagtcc agagcccctc
    18661 cgaaaagcgc ttatacagaa agtcctgttc aagcaggcca aatttccata gatgataagc
    18721 gatgtccttg gctgtatagg ttaaaattcc gttagaacgc accagaacct tatctggact
    18781 atgttccgat tcctggcctt ccgaattagc tgtggactgt tttagtaccc agcagccttc
    18841 cagcttacct gaagtttcct ggtgaaattg ctctgtttct ttcagcaaat taaatgcgga
    18901 tgcccagaat ccttccctta caatgctgct ctcccatacc aaaagatcat aattaatgcc
    18961 gaacccgttc atttcgtcaa gatgctcacg tacaatccgc tcggccgcaa gtgcgccaac
    19021 ccaagctaaa ttgtcgcctc cctcttccat cgaatgaaga actttgattc tttgttcaag
    19081 taatgaagga ttacactcat actctttatt aactcttgag tatatatccc aacagaaatc
    19141 cccaaaacgt gtatgctcct ccttatgggg gatgttcaaa agccccacta ccgtgtcggc
    19201 aagctgattc cccaggtcat ctatataatt gtgcacctcg acattgtacc cggctctagt
    19261 taaaagtctc acgagagcat caccgataca ggaatttctt aagtgaccaa tgtgcgctga
    19321 tttattcgga ttaatagacg tatgctcaat gacaacctta tcgcctttat ttaggggcat
    19381 ctcaaacttc cgctgggacc attccttcca atcgatatgc atattaatga agcccggttg
    19441 ggcgatttca atcttgctta tcaaatctcc catccgattg tcttgttcca ttttagtctt
    19501 caacatggct gctatttgaa tgggtggttt ccttaacact ctagccagct gcatcgcaac
    19561 attcgttgaa taatcaccat gttctaggag atcaggctgc tcaaccccta aattcactcc
    19621 attcttaccg ttgaccccta gttcgtcaca cacatgttcc actgcatgtt cgatgctgct
    19681 aactaacaat tgactgatca tcccgaatag acctcctttt attaaaaata aaaagccctc
    19741 atctctaata aaagagacga aggcttctgc attcgcggta ccactcttgt tgttaaacct
    19801 aagtttaacc acctcaaaag ataacggtct tagccgtgac ttcctactgc aggattcaga
    19861 agtcattctc atgggtccgt ttccctgtca gcccagtacc ggatctcacc atttccggct
    19921 cgctttgact tgaattaaca ggtactctcc caatcctcga atttgatgta ttttgtatat
    19981 tatatccaat acatgattaa agtcaattcc ccagctctac gctgttattt cgctctatcc
    20041 accagactcg acataaaaat ctaatccata gtgaaacagc aggcatttct acaggtgaaa
    20101 atgggcgtac actcaccaca gataaccatg cgacatcaag tcgattggat acctttaaaa
    20161 acatgggtaa caatctgctc tacatagctg tcgttaatcg ggtcccccgt aactaacaag
    20221 cggtagaata tcggcccgta aatgagatcc gtgcataatg cgatatcaac attcttttcc
    20281 aactctccac gctgaagggc tctagtcata atatcccgga cctcaagccg ccggggctga
    20341 atataacgtg ttcgaaatgc ctcagcgagt gcagaatcaa cctgcccctc acctataatc
    20401 tccagaaaaa tagaaccttc acggcttacc ataaacctgg ccatattcgt ggcatgttcc
    20461 agaatatcct gaaataccga acctgtatcc ggtacaggca atcttgctgc cgcagcggat
    20521 aggaacccgt ccatgaccac ggcggccttg ttgggccacc atttataaat agtggctttg
    20581 cttacctgag cacgttcagc gattttttct accgttaccg ctccaaagcc gctttccagc
    20641 aataattcat aagaagcgga caggatggag ctttgcgttt ccatattacg tggacggcct
    20701 cttttcccct gcatatgaat tcctcctttg cttttctccg tttcatcact atataaacta
    20761 tacgtttagt atacaaaaaa tgaaattcga aaaaaagcct atttacaaaa cgatacgttc
    20821 agtatattat ttaaatcaag aaatacaaaa ctaaacgttc agtatttatt gaggaggata
    20881 tttatgttaa aagaacaagg taaacaagac agctctatct ccagttggat gatgtttctg
    20941 cttgcagctg catgcggtct tattgttgcc aatctgtatt acgcccaaac cctggtgggg
    21001 cctatccgtg atgcaacggg tcttacttcc tcaaccgcag gattaatcgt cacagtgacc
    21061 caaatcggtt atgtagccgg cctgctgttc atcgtaccgc tgagcgacat cgttgagaac
    21121 cggcgcctta cgatcgtcat gttaatcata gccattggcg cattgttaac tgccgcgttc
    21181 tcacctaacg catcgctctt tttgaccgca tctcttttta ttggaattgg ttctgttgtg
    21241 gcccagattc tagtgccgtt cgccgcctat ctatcatccg agaatcaacg cggccgtgtg
    21301 gtcggtaatg tgatgagtgg actcctgctc ggaattatgt tcgcccggcc gttggcaagt
    21361 tttatcacca gtctttgggg ctggagagct atatttattc tgtctgccat tgtgatcact
    21421 ttactaacta tactgctatc ctttgcactt cccgaacgta agccactccc cacagtacgc
    21481 tacggcaaac taattctctc tttaggcact atattacgac aaacgccggc attacggcgc
    21541 cgcgcactgt atcaagcttt cttatttgga gccttcagtt tattttggac tgtcgtgcct
    21601 ctaca
//
