GCF_900445255.1_51485_H01_genomic - 3 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_UAPU01000005 (original name was: NZ_UAPU01000005.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 3.1	T1PKS	922,590	970,314

NZ_UAPU01000007 (original name was: NZ_UAPU01000007.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 6.1	terpene	1,039,430	1,060,443
Region 6.2	arylpolyene	1,182,679	1,226,275	APE Ec	Other	31%

Region	Type	From	To	Most similar known cluster	Similarity
Region 3.1	T1PKS	922,590	970,314
Region 6.1	terpene	1,039,430	1,060,443
Region 6.2	arylpolyene	1,182,679	1,226,275	APE Ec	Other	31%

No secondary metabolite regions were found in these records:: NZ_UAPU01000010 (original name was: NZ_UAPU01000010.1); NZ_UAPU01000008 (original name was: NZ_UAPU01000008.1); NZ_UAPU01000004 (original name was: NZ_UAPU01000004.1); NZ_UAPU01000009 (original name was: NZ_UAPU01000009.1); NZ_UAPU01000006 (original name was: NZ_UAPU01000006.1); NZ_UAPU01000003 (original name was: NZ_UAPU01000003.1); NZ_UAPU01000002 (original name was: NZ_UAPU01000002.1); NZ_UAPU01000001 (original name was: NZ_UAPU01000001.1)

Compact view

c00003_NZ_UAPU.. - Region 1 - T1PKS

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Location: 922,590 - 970,314 nt. (total: 47,725 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001909.1	0.31	Polyketide	strobilurin	Strobilurus tenacellus
BGC0000807.1	0.22	Saccharide	phosphonoglycans	Stackebrandtia nassauensis DSM 44728
BGC0001264.1	0.22	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0001280.1	0.22	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001244.1	0.21	Polyketide	(-)-Mellein	Parastagonospora nodorum
BGC0001400.1	0.20	Polyketide	citreoviridin	Aspergillus terreus NIH2624
BGC0001998.1	0.20	Polyketide	aspernidgulene A1, aspernidgulene A2, aspernidgulene B1	Aspergillus nidulans FGSC A4
BGC0001273.1	0.20	Polyketide	asperlactone	Aspergillus ochraceus
BGC0001749.1	0.18	Polyketide	epipyriculol	Pyricularia oryzae 70-15
BGC0001254.1	0.18	Polyketide	ACT-Toxin II	Alternaria alternata

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001909.1	0.64	Polyketide	strobilurin	Strobilurus tenacellus
BGC0000807.1	0.55	Saccharide	phosphonoglycans	Stackebrandtia nassauensis DSM 44728
BGC0001264.1	0.54	Polyketide	betaenone A, betaenone B, betaenone C	Phoma betae
BGC0001280.1	0.54	Polyketide	betaenone C, betaenone A	Phoma betae
BGC0001244.1	0.54	Polyketide	(-)-Mellein	Parastagonospora nodorum
BGC0001400.1	0.53	Polyketide	citreoviridin	Aspergillus terreus NIH2624
BGC0001998.1	0.53	Polyketide	aspernidgulene A1, aspernidgulene A2, aspernidgulene B1	Aspergillus nidulans FGSC A4
BGC0001273.1	0.53	Polyketide	asperlactone	Aspergillus ochraceus
BGC0001749.1	0.50	Polyketide	epipyriculol	Pyricularia oryzae 70-15
BGC0001254.1	0.50	Polyketide	ACT-Toxin II	Alternaria alternata

Similar known gene clusters

No matches found.

Module view

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Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 922589 - 970314:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg3_777

PKS_AT (554..847): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%; inactive: 54.2%; Methylmalonyl-CoA: 54.2%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 79.3
Methoxymalonyl-CoA: 67.4
Malonyl-CoA: 40.2
Ethylmalonyl-CoA: 36.9
trans-1,2-CPDA: 35.3
Propionyl-CoA: 34.9
2-Methylbutyryl-CoA: 28.1
Isobutyryl-CoA: 24.3
inactive: 20.3
CHC-CoA: 19.7
fatty_acid: 11.8
Acetyl-CoA: 10.2
Benzoyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

c00006_NZ_UAPU.. - Region 1 - terpene

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Location: 1,039,430 - 1,060,443 nt. (total: 21,014 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000294.1	0.15	NRP	acinetobactin	Acinetobacter baumannii
BGC0001928.1	0.15	Other	(2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid	Streptomyces sp. MA37
BGC0001289.1	0.14	RiPP	penisin	Paenibacillus ehimensis
BGC0000451.1	0.14	NRP	turnerbactin	Teredinibacter turnerae T7901
BGC0001475.1	0.11	Polyketide	aspterric acid	Aspergillus terreus NIH2624
BGC0001047.1	0.07	NRP, Polyketide	syringolin A	Pseudomonas syringae
BGC0000399.1	0.07	NRP	orfamide A, orfamide C	Pseudomonas protegens Pf-5
BGC0001207.1	0.07	NRP	teixobactin	Eleftheria terrae
BGC0001051.1	0.06	NRP, Polyketide	thuggacin A	Sorangium cellulosum
BGC0001515.1	0.06	NRP	aspercryptins	Aspergillus nidulans FGSC A4

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000294.1	0.45	NRP	acinetobactin	Acinetobacter baumannii
BGC0001928.1	0.45	Other	(2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid	Streptomyces sp. MA37
BGC0001289.1	0.43	RiPP	penisin	Paenibacillus ehimensis
BGC0000451.1	0.43	NRP	turnerbactin	Teredinibacter turnerae T7901
BGC0001475.1	0.39	Polyketide	aspterric acid	Aspergillus terreus NIH2624
BGC0001047.1	0.29	NRP, Polyketide	syringolin A	Pseudomonas syringae
BGC0000399.1	0.28	NRP	orfamide A, orfamide C	Pseudomonas protegens Pf-5
BGC0001207.1	0.28	NRP	teixobactin	Eleftheria terrae
BGC0001051.1	0.27	NRP, Polyketide	thuggacin A	Sorangium cellulosum
BGC0001515.1	0.27	NRP	aspercryptins	Aspergillus nidulans FGSC A4

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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c00006_NZ_UAPU.. - Region 2 - arylpolyene

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Location: 1,182,679 - 1,226,275 nt. (total: 43,597 nt) Show pHMM detection rules used

arylpolyene: (APE_KS1 or APE_KS2)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002008.1	0.34	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0000836.1	0.32	Other	APE Ec	Escherichia coli CFT073
BGC0000837.1	0.22	Other	APE Vf	Aliivibrio fischeri ES114
BGC0000194.1	0.21	Polyketide	actinorhodin	Streptomyces coelicolor A3(2)
BGC0001400.1	0.20	Polyketide	citreoviridin	Aspergillus terreus NIH2624
BGC0000204.1	0.20	Polyketide	benastatin A, benastatin B, BE-43767, TAN1532B	Streptomyces sp. A2991200
BGC0001897.1	0.19	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0000938.1	0.19	Other (Aminocoumarin)	fosfomycin	Streptomyces fradiae
BGC0000840.1	0.19	Other	xanthomonadin I	Xanthomonas oryzae pv. oryzae
BGC0001895.1	0.19	Polyketide	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002008.1	0.67	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0000836.1	0.66	Other	APE Ec	Escherichia coli CFT073
BGC0000837.1	0.55	Other	APE Vf	Aliivibrio fischeri ES114
BGC0000194.1	0.54	Polyketide	actinorhodin	Streptomyces coelicolor A3(2)
BGC0001400.1	0.52	Polyketide	citreoviridin	Aspergillus terreus NIH2624
BGC0000204.1	0.52	Polyketide	benastatin A, benastatin B, BE-43767, TAN1532B	Streptomyces sp. A2991200
BGC0001897.1	0.51	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0000938.1	0.51	Other (Aminocoumarin)	fosfomycin	Streptomyces fradiae
BGC0000840.1	0.51	Other	xanthomonadin I	Xanthomonas oryzae pv. oryzae
BGC0001895.1	0.51	Polyketide	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names