GCF_004340975.1_ASM434097v1_genomic - 3 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_SLXA01000002 (original name was: NZ_SLXA01000002.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	lanthipeptide-class-ii	9,685	32,495

NZ_SLXA01000005 (original name was: NZ_SLXA01000005.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 5.1	ranthipeptide	1	14,904

NZ_SLXA01000021 (original name was: NZ_SLXA01000021.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 21.1	lanthipeptide-class-ii	1	20,275

Region	Type	From	To	Similarity
Region 2.1	lanthipeptide-class-ii	9,685	32,495
Region 5.1	ranthipeptide	1	14,904
Region 21.1	lanthipeptide-class-ii	1	20,275

No secondary metabolite regions were found in these records:: NZ_SLXA01000001 (original name was: NZ_SLXA01000001.1); NZ_SLXA01000003 (original name was: NZ_SLXA01000003.1); NZ_SLXA01000004 (original name was: NZ_SLXA01000004.1); NZ_SLXA01000006 (original name was: NZ_SLXA01000006.1); NZ_SLXA01000007 (original name was: NZ_SLXA01000007.1); NZ_SLXA01000008 (original name was: NZ_SLXA01000008.1); NZ_SLXA01000009 (original name was: NZ_SLXA01000009.1); NZ_SLXA01000010 (original name was: NZ_SLXA01000010.1); NZ_SLXA01000011 (original name was: NZ_SLXA01000011.1); NZ_SLXA01000012 (original name was: NZ_SLXA01000012.1); NZ_SLXA01000013 (original name was: NZ_SLXA01000013.1); NZ_SLXA01000014 (original name was: NZ_SLXA01000014.1); NZ_SLXA01000015 (original name was: NZ_SLXA01000015.1); NZ_SLXA01000016 (original name was: NZ_SLXA01000016.1); NZ_SLXA01000017 (original name was: NZ_SLXA01000017.1); NZ_SLXA01000018 (original name was: NZ_SLXA01000018.1); NZ_SLXA01000019 (original name was: NZ_SLXA01000019.1); NZ_SLXA01000020 (original name was: NZ_SLXA01000020.1); NZ_SLXA01000022 (original name was: NZ_SLXA01000022.1); NZ_SLXA01000023 (original name was: NZ_SLXA01000023.1); NZ_SLXA01000024 (original name was: NZ_SLXA01000024.1); NZ_SLXA01000025 (original name was: NZ_SLXA01000025.1); NZ_SLXA01000026 (original name was: NZ_SLXA01000026.1); NZ_SLXA01000027 (original name was: NZ_SLXA01000027.1); NZ_SLXA01000028 (original name was: NZ_SLXA01000028.1); NZ_SLXA01000029 (original name was: NZ_SLXA01000029.1); NZ_SLXA01000030 (original name was: NZ_SLXA01000030.1); NZ_SLXA01000031 (original name was: NZ_SLXA01000031.1); NZ_SLXA01000032 (original name was: NZ_SLXA01000032.1); NZ_SLXA01000033 (original name was: NZ_SLXA01000033.1); NZ_SLXA01000034 (original name was: NZ_SLXA01000034.1); NZ_SLXA01000035 (original name was: NZ_SLXA01000035.1)

Compact view

c00002_NZ_SLXA.. - Region 1 - lanthipeptide-class-ii

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Location: 9,685 - 32,495 nt. (total: 22,811 nt) Show pHMM detection rules used

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Lanthipeptides

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000525.1	0.25	RiPP	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0000528.1	0.23	RiPP	michiganin A	Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0000504.1	0.23	RiPP	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000626.1	0.20	RiPP	thuricin	Bacillus thuringiensis
BGC0000539.1	0.20	RiPP	nukacin ISK-1	Staphylococcus warneri
BGC0000516.1	0.19	RiPP	geobacillin II	Geobacillus thermodenitrificans
BGC0000521.1	0.19	RiPP	lacticin 481	Lactococcus lactis subsp. lactis
BGC0001660.1	0.19	RiPP	mathermycin	Marinactinospora thermotolerans
BGC0001407.1	0.18	RiPP	bicereucin	Bacillus cereus SJ1
BGC0001787.1	0.16	RiPP	suicin 3908	Streptococcus suis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000525.1	0.58	RiPP	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0000528.1	0.57	RiPP	michiganin A	Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0000504.1	0.56	RiPP	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000626.1	0.53	RiPP	thuricin	Bacillus thuringiensis
BGC0000539.1	0.52	RiPP	nukacin ISK-1	Staphylococcus warneri
BGC0000516.1	0.51	RiPP	geobacillin II	Geobacillus thermodenitrificans
BGC0000521.1	0.51	RiPP	lacticin 481	Lactococcus lactis subsp. lactis
BGC0001660.1	0.51	RiPP	mathermycin	Marinactinospora thermotolerans
BGC0001407.1	0.50	RiPP	bicereucin	Bacillus cereus SJ1
BGC0001787.1	0.47	RiPP	suicin 3908	Streptococcus suis

Similar known gene clusters

No matches found.

Lanthipeptide predictions

Lanthipeptide(s) for ctg2_31 - Putative Class II

ctg2_32 leader / core peptide: VIEKSFLYA - GNLEEEIREIRGLVEKDhaDGLEQKDDhaFDhaVECDhaPILDhbIYCC
allorf_011598_011735 leader / core peptide: VIRFPAFLRSFFAG - EPACRDhaLIKKFRFYDhaAFLKKPCIDhbPRKGKIR
allorf_029229_029357 leader / core peptide: LMGWGIDTGKQARYIGEMKITGG - LKRYCDhaWPDhbGCFLIQYDhaLL
allorf_030024_030203 leader / core peptide: VPGKSDKLISSQSRYG - LFGDhbDhaPFDEGDhaAYEDhaEPLLLYYIFEGFDhaNDhbFYDhbNDhaEIFICRDhaL

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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Lanthipeptides

Core peptide predictions

ctg2_32 - Class II

Cleavage pHMM score: -5.80

RODEO score: 0

Monoisotopic mass: 4311.1 Da

Molecular weight: 4313.8 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 4331.8 Da N = 1; 4349.9 Da N = 2

allorf_011598_011735 - Class II

Cleavage pHMM score: -4.70

RODEO score: 0

Monoisotopic mass: 3627.1 Da

Molecular weight: 3629.4 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 3647.4 Da N = 1

allorf_029229_029357 - Class II

Cleavage pHMM score: -4.30

RODEO score: 0

Monoisotopic mass: 2236.2 Da

Molecular weight: 2237.7 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 2255.7 Da N = 1

allorf_030024_030203 - Class II

Cleavage pHMM score: -6.80

RODEO score: 0

Monoisotopic mass: 4804.3 Da

Molecular weight: 4807.3 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 4825.3 Da N = 1; 4843.3 Da N = 2; 4861.3 Da N = 3; 4879.3 Da N = 4; 4897.4 Da N = 5; 4915.4 Da N = 6; 4933.4 Da N = 7; 4951.4 Da N = 8

c00005_NZ_SLXA.. - Region 1 - ranthipeptide

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Location: 1 - 14,904 nt. (total: 14,904 nt) Show pHMM detection rules used

Region on contig edge.

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001891.1	0.41	Other	closthioamide	Ruminiclostridium cellulolyticum H10
BGC0001387.1	0.17	Other	nucleocidin	Streptomyces calvus
BGC0000599.1	0.15	RiPP	thuricin CD α, thuricin CD β	Bacillus thuringiensis
BGC0000466.1	0.14	NRP	yatakemycin	Streptomyces sp. TP-A2060
BGC0001607.1	0.13	Other	gilvusmycin	Streptomyces sp. NRRL B-1347
BGC0001540.1	0.13	Other	CC-1065	Streptomyces zelensis
BGC0000807.1	0.10	Saccharide	phosphonoglycans	Stackebrandtia nassauensis DSM 44728
BGC0001591.1	0.07	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.07	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0001089.1	0.04	Polyketide, NRP	bacillaene	Bacillus velezensis FZB42

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001891.1	0.73	Other	closthioamide	Ruminiclostridium cellulolyticum H10
BGC0001387.1	0.48	Other	nucleocidin	Streptomyces calvus
BGC0000599.1	0.45	RiPP	thuricin CD α, thuricin CD β	Bacillus thuringiensis
BGC0000466.1	0.44	NRP	yatakemycin	Streptomyces sp. TP-A2060
BGC0001607.1	0.42	Other	gilvusmycin	Streptomyces sp. NRRL B-1347
BGC0001540.1	0.42	Other	CC-1065	Streptomyces zelensis
BGC0000807.1	0.35	Saccharide	phosphonoglycans	Stackebrandtia nassauensis DSM 44728
BGC0001591.1	0.28	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.28	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0001089.1	0.20	Polyketide, NRP	bacillaene	Bacillus velezensis FZB42

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

c00021_NZ_SLXA.. - Region 1 - lanthipeptide-class-ii

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Location: 1 - 20,275 nt. (total: 20,275 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Lanthipeptides

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000516.1	0.19	RiPP	geobacillin II	Geobacillus thermodenitrificans
BGC0000554.1	0.18	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0001210.1	0.15	RiPP	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0000517.1	0.13	RiPP	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0000761.1	0.13	Saccharide	exopolysaccharide	Methylobacillus sp. 12S
BGC0001281.1	0.04	Polyketide	ustilagic acid	Ustilago maydis 521

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000516.1	0.51	RiPP	geobacillin II	Geobacillus thermodenitrificans
BGC0000554.1	0.49	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0001210.1	0.46	RiPP	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0000517.1	0.41	RiPP	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0000761.1	0.41	Saccharide	exopolysaccharide	Methylobacillus sp. 12S
BGC0001281.1	0.19	Polyketide	ustilagic acid	Ustilago maydis 521

Similar known gene clusters

No matches found.

Lanthipeptide predictions

Lanthipeptide(s) for ctg21_10 - Putative Class II

allorf_10295_10447 leader / core peptide: MENRKNENSMNLAGDIRKEMDEIQKM - QADhbDhbPLILDhaMVDhbNDhbCADLDhbDhbVICC

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

Lanthipeptides

Core peptide predictions

allorf_10295_10447 - Class II

Cleavage pHMM score: -3.30

RODEO score: 0

Monoisotopic mass: 2385.2 Da

Molecular weight: 2386.8 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 2404.9 Da N = 1; 2422.9 Da N = 2; 2440.9 Da N = 3; 2458.9 Da N = 4