LOCUS       NZ_CP015401.2          20351 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP015401.2 Bacteroides caecimuris strain I48 chromosome, complete
            genome.
ACCESSION   NZ_CP015401
VERSION     NZ_CP015401.2
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:04:11
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 847651
            Orig. end    :: 868002
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20351
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[857651:858002](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10351
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..20351
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20351
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             2158..3168
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_633"
                     /sec_met_domain="PF04055 (E-value: 4e-16, bitscore: 57.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLVELQSLTKRLGMPGFAAKQIASWLYEKKVTSIDDMTNLSLKH
                     RELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATLCVSSQVGC
                     KMNCKFCMTGKQGYTANLTASQIMNQIHSLPERDKLTNVVMMGMGEPLDNLDEVLKALE
                     LLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAELMPAEKAF
                     SITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRVNLIRFHAI
                     PGVDLEGADMDTMTRFRDYLTSHGIFTTIRSSRGEDIFAACGMLSTAKQEKNNES"
     aSDomain        2161..3153
                     /aSDomain="TIGR00048"
                     /aSTool="tigrfam"
                     /description="rRNA_mod_RlmN: 23S rRNA
                     (adenine(2503)-C(2))-methyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_633_0001"
                     /evalue="3.10E-108"
                     /identifier="TIGR00048"
                     /label="ctg1_633"
                     /locus_tag="ctg1_633"
                     /protein_end="332"
                     /protein_start="1"
                     /score="359.8"
                     /tool="antismash"
                     /translation="TLVELQSLTKRLGMPGFAAKQIASWLYEKKVTSIDDMTNLSLKHR
                     ELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATLCVSSQVGCK
                     MNCKFCMTGKQGYTANLTASQIMNQIHSLPERDKLTNVVMMGMGEPLDNLDEVLKALEL
                     LTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAELMPAEKAFS
                     ITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRVNLIRFHAIP
                     GVDLEGADMDTMTRFRDYLTSHGIFTTIRSSRGEDIFAACGMLSTAKQEK"
     PFAM_domain     2452..2928
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_633_0001"
                     /evalue="2.50E-15"
                     /label="ctg1_633"
                     /locus_tag="ctg1_633"
                     /protein_end="257"
                     /protein_start="98"
                     /score="57.3"
                     /tool="antismash"
                     /translation="SSQVGCKMNCKFCMTGKQGYTANLTASQIMNQIHSLPERDKLTNV
                     VMMGMGEPLDNLDEVLKALELLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAI
                     SLHSPLTVQRAELMPAEKAFSITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQV"
     CDS             3187..4230
                     /locus_tag="ctg1_634"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKVIVDFFTRAEMNRQIMLLEGKHSNFV
                     SQKVDSLFGCDIWVDAELVSSKTRDDFFWASTNTGSADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVKNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEIQQSQIPLGGEVSK
                     EAEQTNK"
     PFAM_domain     3268..4146
                     /aSDomain="DUF4837"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16125.7"
                     /description="Domain of unknown function (DUF4837)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_634_0002"
                     /evalue="2.00E-107"
                     /label="ctg1_634"
                     /locus_tag="ctg1_634"
                     /protein_end="320"
                     /protein_start="27"
                     /score="358.7"
                     /tool="antismash"
                     /translation="SSGRAYELLVVVDHGVWDRAAGRALHDALDADMPGLPQSEPSFRI
                     MYTSPKDYDSTLKLIRNIIIVDIQDIYTKASFKYAKDVYANPQMILTIQAPNEEEFEKF
                     VEENKKVIVDFFTRAEMNRQIMLLEGKHSNFVSQKVDSLFGCDIWVDAELVSSKTRDDF
                     FWASTNTGSADRNFVMYSYPYTDKDTFTKEYFVHKRDSVMKANIPGFKEGVYMSTDSLL
                     TDVRPINVKNSYTMEARGLWRMKGDFMGGPYVSHTRLDEKNQRIITAEIFVYSPDKMKR
                     NLVRQMEASLYT"
     CDS             4235..5329
                     /locus_tag="ctg1_635"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPMMLELCTPIIYGSPK
                     VAAYHRKALDIQTNFSIINSATEAVCNRLSVVNCTDDEVKVEFSKLDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGGKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGVACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     aSDomain        4253..5215
                     /aSDomain="TIGR00557"
                     /aSTool="tigrfam"
                     /description="pdxA: 4-hydroxythreonine-4-phosphate
                     dehydrogenase PdxA"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_635_0002"
                     /evalue="1.70E-110"
                     /identifier="TIGR00557"
                     /label="ctg1_635"
                     /locus_tag="ctg1_635"
                     /protein_end="327"
                     /protein_start="6"
                     /score="367.4"
                     /tool="antismash"
                     /translation="RIGITQGDINGVGYEVILKTFSDPMMLELCTPIIYGSPKVAAYHR
                     KALDIQTNFSIINSATEAVCNRLSVVNCTDDEVKVEFSKLDPEAGKAALGALERAIEEY
                     REGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGGKSLMILMKNDFRVALVTTH
                     IPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLGMEEQEV
                     IIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAMEDGVNY
                     TAGLPVVRTSPAHGTAYDIAGKGVACEDSFRQAIYVAIDV"
     PFAM_domain     4337..5206
                     /aSDomain="PdxA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04166.14"
                     /description="Pyridoxal phosphate biosynthetic protein
                     PdxA"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_635_0003"
                     /evalue="6.00E-104"
                     /label="ctg1_635"
                     /locus_tag="ctg1_635"
                     /protein_end="324"
                     /protein_start="34"
                     /score="347.5"
                     /tool="antismash"
                     /translation="LCTPIIYGSPKVAAYHRKALDIQTNFSIINSATEAVCNRLSVVNC
                     TDDEVKVEFSKLDPEAGKAALGALERAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGH
                     TEYIEERLGNGGKSLMILMKNDFRVALVTTHIPVREIATTITKELIQEKLMIFHRCLKQ
                     DFGIGAPRIAVLSLNPHAGDGGLLGMEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSG
                     NYTHFDGILAMYHDQGLAPFKALAMEDGVNYTAGLPVVRTSPAHGTAYDIAGKGVACED
                     SFRQAIYVA"
     CDS             5342..6580
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 350.7; E-value:
                     2.2e-106)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_636"
                     /transl_table=11
                     /translation="MKAEIQQVKQRFGIIGNTEALLRAIDVAIQVAPTDLSVLITGESG
                     VGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFGE
                     ADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAIA
                     DGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKEL
                     LAYSWPGNVRQLKNITEQISIIETNREISAAILQNYLPVQNTQRLPALMGTRESKGFES
                     EREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPAI
                     IHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNISE
                     RTLYRKIKEYGLD"
     PFAM_domain     5381..5884
                     /aSDomain="Sigma54_activat"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00158.28"
                     /description="Sigma-54 interaction domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_636_0004"
                     /evalue="6.40E-66"
                     /label="ctg1_636"
                     /locus_tag="ctg1_636"
                     /protein_end="181"
                     /protein_start="13"
                     /score="221.3"
                     /tool="antismash"
                     /translation="IIGNTEALLRAIDVAIQVAPTDLSVLITGESGVGKESFPQIIHQY
                     SRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFGEADGGTIFLDEVGE
                     LPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAIADGRFREDLYYRLN
                     TVPIQ"
     PFAM_domain     6443..6568
                     /aSDomain="HTH_8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02954.21"
                     /description="Bacterial regulatory protein, Fis family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_636_0005"
                     /evalue="3.60E-15"
                     /label="ctg1_636"
                     /locus_tag="ctg1_636"
                     /protein_end="409"
                     /protein_start="367"
                     /score="55.5"
                     /tool="antismash"
                     /translation="SLDEVEKEMIRKALERHHGKRKSAAKDLNISERTLYRKIKEY"
     CDS             6567..7094
                     /locus_tag="ctg1_637"
                     /transl_table=11
                     /translation="MDWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     PFAM_domain     6681..7076
                     /aSDomain="LptE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04390.14"
                     /description="Lipopolysaccharide-assembly"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_637_0006"
                     /evalue="2.10E-16"
                     /label="ctg1_637"
                     /locus_tag="ctg1_637"
                     /protein_end="170"
                     /protein_start="38"
                     /score="60.7"
                     /tool="antismash"
                     /translation="VKTISIADFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQ
                     NADLQIDGEITGYNQYNQAVSADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTY
                     DSSQLLTAVQDGLIAEMSKEITDQIFNA"
     CDS             7100..7873
                     /locus_tag="ctg1_638"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTAPEEVTARTSFDYSMDYTSYLLEETPAAEQPVEETPKLKGYELIDDFIEK
                     SESDSPFCKKPLREEMPSSPTSSNEPTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             7880..8227
                     /locus_tag="ctg1_639"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVIPSSDVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTNAVQQDSVN"
     aSDomain        7883..8092
                     /aSDomain="TIGR00810"
                     /aSTool="tigrfam"
                     /description="secG: preprotein translocase, SecG subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_639_0003"
                     /evalue="1.60E-19"
                     /identifier="TIGR00810"
                     /label="ctg1_639"
                     /locus_tag="ctg1_639"
                     /protein_end="71"
                     /protein_start="1"
                     /score="67.7"
                     /tool="antismash"
                     /translation="YLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRKT
                     TDFLEKATWGLAIFMVVMSIATAYV"
     PFAM_domain     7892..8092
                     /aSDomain="SecG"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03840.16"
                     /description="Preprotein translocase SecG subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_639_0007"
                     /evalue="8.60E-18"
                     /label="ctg1_639"
                     /locus_tag="ctg1_639"
                     /protein_end="71"
                     /protein_start="4"
                     /score="64.4"
                     /tool="antismash"
                     /translation="FVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRKTTDF
                     LEKATWGLAIFMVVMSIATAYV"
     CDS             8329..9975
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 29.6; E-value: 4.5e-09)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_640"
                     /transl_table=11
                     /translation="VKTTLRDSAAMRWTVLLFLAFAMFCSYIFMDILSPIKDLMQSTRG
                     WDSTAFGTMQGSETFLNVFVFFLIFAGIILDKMGVRFTAVLSGVVMLVGAVINWYAVTT
                     AFAGSDLETWFNNNLNYIPVFDELGISPFYRGMPASAKLSAVGFMIFGCGVEMAGITVS
                     RGIVKWFKGREMALAMGSEMALARLGVATCMIFSPVFAKLGGVIDVSRSVAFGVVLLMI
                     ALIMFIVYFFMDKKLDAQTGEAEEKDDPFKISDLGTILKSSGFWLVALLCVLYYSAILP
                     FQKYAVNMLQCNLTFTEVSPDSFWATNTVTIIQYCIMLVVAAAAFASNFSKSKNLKSGL
                     LMLAVVALVVFCYMGYMRQSAETVFAVFPLLAVGITPILGNYVDHKGKAASMLVMGSVL
                     LILCHLTFAFVLPGFKGNPVGGIIVAYLTILVLGASFSLVPASLWPSVPKLVDAKIIGS
                     AYALIFWIQNIGLWLFPLLIGKVLDRTNPQLVSDLKNGVITPEEAATAYDYTAPLVMLA
                     CLGGAALILGFVLKIVDKKKGYGLEEPNIKE"
     PFAM_domain     8383..9396
                     /aSDomain="MFS_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07690.18"
                     /description="Major Facilitator Superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_640_0008"
                     /evalue="2.70E-14"
                     /label="ctg1_640"
                     /locus_tag="ctg1_640"
                     /protein_end="356"
                     /protein_start="18"
                     /score="53.0"
                     /tool="antismash"
                     /translation="LAFAMFCSYIFMDILSPIKDLMQSTRGWDSTAFGTMQGSETFLNV
                     FVFFLIFAGIILDKMGVRFTAVLSGVVMLVGAVINWYAVTTAFAGSDLETWFNNNLNYI
                     PVFDELGISPFYRGMPASAKLSAVGFMIFGCGVEMAGITVSRGIVKWFKGREMALAMGS
                     EMALARLGVATCMIFSPVFAKLGGVIDVSRSVAFGVVLLMIALIMFIVYFFMDKKLDAQ
                     TGEAEEKDDPFKISDLGTILKSSGFWLVALLCVLYYSAILPFQKYAVNMLQCNLTFTEV
                     SPDSFWATNTVTIIQYCIMLVVAAAAFASNFSKSKNLKSGLLMLAVVALVVFCYMGY"
     CDS             10001..10351
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_641"
                     /sec_met_domain="PF05402 (E-value: 2.3e-15, bitscore: 54.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 5e-09, bitscore: 33.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAKREGETMVLSFPRFKYPWMQRFL
                     VPKGMSKELHVQLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
     PFAM_domain     10166..10327
                     /aSDomain="PqqD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05402.14"
                     /description="Coenzyme PQQ synthesis protein D (PqqD)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_641_0009"
                     /evalue="2.20E-14"
                     /label="ctg1_641"
                     /locus_tag="ctg1_641"
                     /protein_end="109"
                     /protein_start="55"
                     /score="53.6"
                     /tool="antismash"
                     /translation="VQLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYL
                     SQMQKDGFI"
     CDS             complement(10366..10650)
                     /locus_tag="ctg1_642"
                     /transl_table=11
                     /translation="MGGEGYMLDMIRRLSEGREASRLRRERANDKLKHLNRTNEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(10687..11754)
                     /locus_tag="ctg1_643"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTQGKDYGVVYSLPKTLIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSANSEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSAGKKTAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANHDLAGTPFYISLKDLKSVKIPQEDGK
                     KKKDLDGIAYNVPGQALVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     PFAM_domain     complement(10717..11661)
                     /aSDomain="DUF4831"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16115.7"
                     /description="Domain of unknown function (DUF4831)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_643_0010"
                     /evalue="2.10E-125"
                     /label="ctg1_643"
                     /locus_tag="ctg1_643"
                     /protein_end="346"
                     /protein_start="31"
                     /score="418.2"
                     /tool="antismash"
                     /translation="YGVVYSLPKTLIELEIKANKVNYTPGEFSKYADRYLRLTNVSANS
                     EEYWELASVKVKSVGVPNSETTYFVKLKDKTVAPLMELTEDGIVKTINVPYSNSSAGKK
                     TAPAPAVLQKKANPREFLTEEILMASSTAKMAELVAKEIYNIRESKNALLRGQADNMPS
                     DGAQLKIMLDNLNAQEEAMTQMFSGTCNKEERTFTVRLTPDKEFNNEVAFRFSKKLGVV
                     ANHDLAGTPFYISLKDLKSVKIPQEDGKKKKDLDGIAYNVPGQALVTLTDGKKKLYEGE
                     LPITQFGVIEYLAPVLFNKNSTIKVYFDPNTGGL"
     CDS             complement(11828..13339)
                     /locus_tag="ctg1_644"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATALTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEI
                     KFHEISTQFVPPALTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEEIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARTAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGLIASDIITCLPTAWRLVSE"
     aSDomain        complement(11843..12649)
                     /aSDomain="TIGR00196"
                     /aSTool="tigrfam"
                     /description="yjeF_cterm: YjeF family C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_644_0004"
                     /evalue="5.80E-67"
                     /identifier="TIGR00196"
                     /label="ctg1_644"
                     /locus_tag="ctg1_644"
                     /protein_end="499"
                     /protein_start="230"
                     /score="223.9"
                     /tool="antismash"
                     /translation="EIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSG
                     VGLLTVHAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETE
                     AALLEQLEHCQTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYE
                     RLMKACELARTAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALL
                     AQGYPTEEAAKIGTYIHGLAGDVAQKKQGMIGLIASDIITCLPTAWR"
     PFAM_domain     complement(11858..12586)
                     /aSDomain="Carb_kinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01256.19"
                     /description="Carbohydrate kinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_644_0012"
                     /evalue="1.50E-60"
                     /label="ctg1_644"
                     /locus_tag="ctg1_644"
                     /protein_end="494"
                     /protein_start="251"
                     /score="204.8"
                     /tool="antismash"
                     /translation="LLIAGSKGMAGASVLAARACLRSGVGLLTVHAPMCNNDILQTSIP
                     EAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQLEHCQTPVVVDADAL
                     NILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKACELARTAHVHIILKGA
                     YSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPTEEAAKIGTYIHGLAG
                     DVAQKKQGMIGLIASDIITCL"
     aSDomain        complement(12704..13303)
                     /aSDomain="TIGR00197"
                     /aSTool="tigrfam"
                     /description="yjeF_nterm: YjeF family N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_644_0005"
                     /evalue="2.40E-36"
                     /identifier="TIGR00197"
                     /label="ctg1_644"
                     /locus_tag="ctg1_644"
                     /protein_end="212"
                     /protein_start="12"
                     /score="123.3"
                     /tool="antismash"
                     /translation="DAYTIENEPIASIDLMERAATALTKAITDRWNTETPVTIFAGPGN
                     NGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEIKFHEISTQFVPP
                     ALTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSGLMGEENTFNVKA
                     NIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQL"
     PFAM_domain     complement(12767..13264)
                     /aSDomain="YjeF_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03853.17"
                     /description="YjeF-related protein N-terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_644_0011"
                     /evalue="1.20E-42"
                     /label="ctg1_644"
                     /locus_tag="ctg1_644"
                     /protein_end="191"
                     /protein_start="25"
                     /score="145.9"
                     /tool="antismash"
                     /translation="DLMERAATALTKAITDRWNTETPVTIFAGPGNNGGDALAVARMMA
                     EKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEIKFHEISTQFVPPALTPDHLVIDGLF
                     GSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSGLMGEENTFNVKANIIRADVTFSLQL
                     PKL"
     CDS             14081..14617
                     /locus_tag="ctg1_645"
                     /transl_table=11
                     /translation="MDTIQIKDKLFTVSIKEQDIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGITSTGVIKEVIGLNEDIAGRTIVIVEDI
                     VDTGLTMQRLLETLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     aSDomain        14117..14608
                     /aSDomain="TIGR01203"
                     /aSTool="tigrfam"
                     /description="HGPRTase: hypoxanthine
                     phosphoribosyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_645_0006"
                     /evalue="4.20E-51"
                     /identifier="TIGR01203"
                     /label="ctg1_645"
                     /locus_tag="ctg1_645"
                     /protein_end="176"
                     /protein_start="12"
                     /score="171.0"
                     /tool="antismash"
                     /translation="VSIKEQDIQKEVIRVANEINRDLAGKNPLFLSVLNGSFMFTADLL
                     KHITIPCEISFVKLASYQGITSTGVIKEVIGLNEDIAGRTIVIVEDIVDTGLTMQRLLE
                     TLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDYDGFGRNYPDIYT
                     V"
     PFAM_domain     14132..14569
                     /aSDomain="Pribosyltran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00156.29"
                     /description="Phosphoribosyl transferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_645_0013"
                     /evalue="1.90E-26"
                     /label="ctg1_645"
                     /locus_tag="ctg1_645"
                     /protein_end="163"
                     /protein_start="17"
                     /score="92.4"
                     /tool="antismash"
                     /translation="QDIQKEVIRVANEINRDLAGKNPLFLSVLNGSFMFTADLLKHITI
                     PCEISFVKLASYQGITSTGVIKEVIGLNEDIAGRTIVIVEDIVDTGLTMQRLLETLGTR
                     NPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY"
     CDS             14677..15246
                     /locus_tag="ctg1_646"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSIMLDLEVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTAPLIDWYKNE
                     KKYQHINGLGTMEGIFAEICEAVDKL"
     PFAM_domain     14692..15168
                     /aSDomain="ADK"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00406.24"
                     /description="Adenylate kinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_646_0014"
                     /evalue="3.10E-55"
                     /label="ctg1_646"
                     /locus_tag="ctg1_646"
                     /protein_end="164"
                     /protein_start="5"
                     /score="186.5"
                     /tool="antismash"
                     /translation="IFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTELGKTA
                     KGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAERGQDVS
                     IMLDLEVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTAPLIDWYKNEK"
     CDS             15335..16489
                     /locus_tag="ctg1_647"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKGRSFGKDGADKIIEVPCGTVVYNAET
                     GEYLCDVTEDGQEVILLKGGRGGLGNWHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSSISAAKPKIADYPFTTLEPNLGIVSYHDGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     ITKSDMLDQELMDEIEPTLPEGIPHVFISSVSGLGISVLKDILWEELNKESNKIEAIVH
                     RPKDVTRLQQELKDMGEDEDIVYEYEEDGDDDIDYEYEEDWEEE"
     aSDomain        15350..16318
                     /aSDomain="TIGR02729"
                     /aSTool="tigrfam"
                     /description="Obg_CgtA: Obg family GTPase CgtA"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_647_0007"
                     /evalue="5.70E-128"
                     /identifier="TIGR02729"
                     /label="ctg1_647"
                     /locus_tag="ctg1_647"
                     /protein_end="328"
                     /protein_start="5"
                     /score="424.5"
                     /tool="antismash"
                     /translation="FVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRGGHIIL
                     RGNRNYWTLLHLKYDRHAMAGHGESGSKGRSFGKDGADKIIEVPCGTVVYNAETGEYLC
                     DVTEDGQEVILLKGGRGGLGNWHFKTATRQAPRFAQPGEPMQEMTVIMELKLLADVGLV
                     GFPNAGKSTLLSSISAAKPKIADYPFTTLEPNLGIVSYHDGKSFVMADIPGIIEGASQG
                     KGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLAITKSD
                     MLDQELMDEIEPTLPEGIPHVFISSVSGLGISVLKDILWEEL"
     PFAM_domain     15353..15817
                     /aSDomain="GTP1_OBG"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01018.24"
                     /description="GTP1/OBG"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_647_0015"
                     /evalue="1.60E-56"
                     /label="ctg1_647"
                     /locus_tag="ctg1_647"
                     /protein_end="161"
                     /protein_start="6"
                     /score="190.4"
                     /tool="antismash"
                     /translation="VDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRGGHIILR
                     GNRNYWTLLHLKYDRHAMAGHGESGSKGRSFGKDGADKIIEVPCGTVVYNAETGEYLCD
                     VTEDGQEVILLKGGRGGLGNWHFKTATRQAPRFAQPGEPMQEMTVIMELKL"
     PFAM_domain     15824..16180
                     /aSDomain="MMR_HSR1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01926.25"
                     /description="50S ribosome-binding GTPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_647_0016"
                     /evalue="4.60E-23"
                     /label="ctg1_647"
                     /locus_tag="ctg1_647"
                     /protein_end="282"
                     /protein_start="163"
                     /score="81.6"
                     /tool="antismash"
                     /translation="DVGLVGFPNAGKSTLLSSISAAKPKIADYPFTTLEPNLGIVSYHD
                     GKSFVMADIPGIIEGASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELR
                     TFNPEMLDKQRVLAI"
     CDS             16486..16983
                     /locus_tag="ctg1_648"
                     /transl_table=11
                     /translation="MISLTKHNELKGYKSLDAYPEVAHFVTTRHGGISTGAYGSFNCSP
                     YTNDSCVNVNRNQDWLFQCMNHQIKELFIPEQSHGCASLIINESFFKESLERRRLLLRG
                     MDALITNVPGYCVCVTTADCVPVLLYDKKQHVVAAVHAGWKGTVKHIVSHVMDHMTQKF
                     GT"
     PFAM_domain     16564..16977
                     /aSDomain="Cu-oxidase_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02578.17"
                     /description="Multi-copper polyphenol oxidoreductase
                     laccase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_648_0017"
                     /evalue="7.70E-39"
                     /label="ctg1_648"
                     /locus_tag="ctg1_648"
                     /protein_end="164"
                     /protein_start="26"
                     /score="133.7"
                     /tool="antismash"
                     /translation="TTRHGGISTGAYGSFNCSPYTNDSCVNVNRNQDWLFQCMNHQIKE
                     LFIPEQSHGCASLIINESFFKESLERRRLLLRGMDALITNVPGYCVCVTTADCVPVLLY
                     DKKQHVVAAVHAGWKGTVKHIVSHVMDHMTQKFG"
     CDS             17083..17298
                     /locus_tag="ctg1_649"
                     /transl_table=11
                     /translation="MSLISMKKKETGKYHIDLWEANRIELLNRGVPAEQIEVAGICTYI
                     HHDEFFSARRLGIDSGRILSGIMIRK"
     PFAM_domain     17101..17286
                     /aSDomain="Cu-oxidase_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02578.17"
                     /description="Multi-copper polyphenol oxidoreductase
                     laccase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_649_0018"
                     /evalue="4.40E-16"
                     /label="ctg1_649"
                     /locus_tag="ctg1_649"
                     /protein_end="68"
                     /protein_start="6"
                     /score="59.2"
                     /tool="antismash"
                     /translation="KKKETGKYHIDLWEANRIELLNRGVPAEQIEVAGICTYIHHDEFF
                     SARRLGIDSGRILSGIM"
     CDS             17349..18014
                     /locus_tag="ctg1_650"
                     /transl_table=11
                     /translation="MFEIKVSKEIKDACPVFAGAAVYAAVKNTAYNEGLWQEINAFAGQ
                     LTSTTQMEDIKHQPVIFATREAYKRCGKDPGRYRPSAEALRRRLMRGIPLYQIDTLVDL
                     INLVSLRTGHSIGGFDADKIQGTHLELGIGKAGEPFEGIGRGVLNIEGLPVYRDSFGGI
                     GTPTSDHERTKMDLGTTHILAIVNGYNGKEGLQEAAEMIQTLLRNYTESDGGEIVCFE"
     PFAM_domain     17541..17921
                     /aSDomain="B3_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03483.19"
                     /description="B3/4 domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_650_0019"
                     /evalue="8.20E-18"
                     /label="ctg1_650"
                     /locus_tag="ctg1_650"
                     /protein_end="191"
                     /protein_start="64"
                     /score="64.8"
                     /tool="antismash"
                     /translation="REAYKRCGKDPGRYRPSAEALRRRLMRGIPLYQIDTLVDLINLVS
                     LRTGHSIGGFDADKIQGTHLELGIGKAGEPFEGIGRGVLNIEGLPVYRDSFGGIGTPTS
                     DHERTKMDLGTTHILAIVNGYNG"
     CDS             18043..18684
                     /locus_tag="ctg1_651"
                     /transl_table=11
                     /translation="MKNILILLTVLLLLPLTADGQDKSSFSAREMADVRVATPGLFAKG
                     NHIYLHLDSLKDHEYAFPLPGGKVISAYGTRGGHSGTDIKTCAKDTIRAAFDGVVRMSK
                     PYYAYGNIVVIRHANGLETLYSHNFKNLVKAGDVVKAGQAIGLTGRTGRATTEHVHFET
                     RINGQHFNPNLIFDFKERTLRKECIKCTKNGSKIVVRTHTPDSWVAQSKK"
     PFAM_domain     18274..18558
                     /aSDomain="Peptidase_M23"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01551.24"
                     /description="Peptidase family M23"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_651_0020"
                     /evalue="1.40E-27"
                     /label="ctg1_651"
                     /locus_tag="ctg1_651"
                     /protein_end="172"
                     /protein_start="77"
                     /score="95.8"
                     /tool="antismash"
                     /translation="GHSGTDIKTCAKDTIRAAFDGVVRMSKPYYAYGNIVVIRHANGLE
                     TLYSHNFKNLVKAGDVVKAGQAIGLTGRTGRATTEHVHFETRINGQHFNP"
     CDS             complement(19505..19834)
                     /locus_tag="ctg1_652"
                     /transl_table=11
                     /translation="MKNTLFCLFIFCSVSTFAQNGITFKVEKLSKPEELLHLHSPNEIY
                     ESLILSDMDIEPYEIKEKNIKVPYHIIAKSESPDSLVSFGPNSFFNGIYQAYADHRPFV
                     LSPEL"
ORIGIN
        1 tatggcgttc ctacgtaaac aataaactga tcgaaaaaga agcaaaagca ctgggactga
       61 ctgtttctgc tgctgaaatc caggacatcc tgaaagcagg tgttcatcct ttgttgagac
      121 aaactccttt ccagaatccg caaacaggaa acttcgacaa ggatatgttg aacaagtttc
      181 tcgtggaata tgccaagatg agcgaagcac aaatgccggc acagtatgct gaacaataca
      241 ataacatgta taaatactgg tctttcattc agaaaacact gatcgagagc cgtttggcag
      301 aaaagtatca ggcattggta tctaaagctc ttctttccaa tccggtggaa gcacaggacg
      361 ctttcgatgc aagagtgaac caatacaacg tgttgatggc tggtattcct tactcttctg
      421 tagtggattc tacaatcgta gtgaaagaat cggaactgaa agacttgtat aacaagaaga
      481 aagaacaatt caagcagtat caggaaactc gtgacatcaa gtacattgat gtacaagtga
      541 ctgcaagtgc tgaagacaga gctgctatcc agaaagaagt ggacgaagca actgcacagt
      601 tggctactac aacggaagat tatacttctt tcatccgctc gactggctcg gacgctcctt
      661 atgtagattt gttctataac aaaacagctt tcccgtcaga tgtagttgcc cgtttggact
      721 ctgcttctgt aggtactatt tatggtcctt actataatgg taccgacaat acaatcaact
      781 ctttcaaaat tgtagctaaa gctgctgctg ccgactctgt tgaattccgt cagattcagg
      841 tatacgcaga agatgctgtg aagacaaaga cattggctga cagtatctac aacgctatca
      901 agagtggtgc taactttgct gatctggcaa agaaatatgg tcagaccggt gatgcaaact
      961 ggctaacttc tgcacagtat gaaggtgcgc agatagacgg tgataacctg aaattcatct
     1021 ctactatcaa caatgcaggt gtaaacgaac tggtgaactt gccgatggga caagcaaaca
     1081 taattcttca ggtaacaaac aagaaatctg taaaagacaa atataaaata gctgtcatca
     1141 agcgtgaagt agagttcagc aaagaaactt acaaccgtgc ttataatgat ttcagccagt
     1201 ttatcgcagc taatcctact gtagagaaga tggtagctaa cgctgaagaa gccggttaca
     1261 gattgctcga cagaatggat ttgagcagct ctgaacacaa tatcggtggt gtaagaggta
     1321 caaaagaagc cttgagatgg gcgtttgata aagctaaacc gggtgatgtt tccggcttgt
     1381 acgaatgtgg cgaaagcgat cacatgatgg tagtaggtct ggtaggcatt aagccggaag
     1441 gatatcgtcc gttgaaagca gtacaagatt tgttgagagc tgaaatcgta aaagagaaga
     1501 aagctgaaaa gattatggct gacatgaaag ctgccaatgc aacttcattc aaccaataca
     1561 aagagatgac taatgcagtc agcgactctt tgaagatggt tacttttgca gctcctgcat
     1621 acgtatcagc attgcgcagc agcgaaccgc tggtaggtgc ttatgcttct gcagttgaag
     1681 tgaaccagtt gagcgctcct atcaaaggta atgccggagt atttgtattg caggtatacg
     1741 gtaaggacaa gcagaacgaa acattcgacg caaaagcaga agaagctacg ctgactaaca
     1801 tgcacgcacg ctttgccagc cgtttgatga acgatttgta tctgaaagca aacgtaaagg
     1861 atacacgctt cttgttcttc taagaaatag ttcaccacag attatctgga ttgccacaga
     1921 aatatcttga aggtggcagg taataataac gtggtgcatc atatagacgc gaatcgctcg
     1981 gatttttgat gaataaatcc ggatgattcg cgtcttccgc atttaaaaac ttctctatta
     2041 atcgtcttaa tctgtgaaaa tctgtgttaa tctgtggtga aaccaacttt atttccttac
     2101 atttgcagat ataaactatc aacagaaaga agaatgtcta aatatcccct tttaggaatg
     2161 actcttgtag agcttcaatc attgacaaaa agactgggta tgcccggctt tgctgccaag
     2221 cagattgcat cctggcttta cgaaaagaag gtaacttcga tcgatgatat gactaatttg
     2281 tcattgaaac accgggagtt gctcaagcag aactatgagg taggagcgga agccccggta
     2341 gatgaaatgc gctctgtaga tggtacggtg aagtatcttt ataaagtagg tgagaaccat
     2401 tttgtagaat cggtttatat accggatgat gaccgggcaa cgttgtgcgt gtcgtcacaa
     2461 gtaggttgta agatgaactg taagttctgt atgaccggca aacaggggta taccgctaac
     2521 ctgaccgcca gccagattat gaaccagatt cattcgttgc cggaacggga caaactgacc
     2581 aatgtcgtaa tgatgggaat gggtgagccg ctcgataacc tggatgaggt attgaaagca
     2641 ttggaactac tgaccgctac ctacggttac gcatggagcc cgaagcgtat cacgctttct
     2701 actgtcgggc tacggaaagg attgcagcgt tttatcgaag aaaatgactg ccaccttgcc
     2761 atcagccttc actctccgct gaccgttcag cgtgctgaat taatgccggc ggaaaaggcg
     2821 ttttcaatca ccgaaatggt ggaactgtta aaaaactatg attttagtaa acaacgtcga
     2881 ctttcgtttg aatatattgt ttttaaaggg ctcaatgatt cgcaggtcta tgccaaagag
     2941 ttgctgaaac ttcttcgcgg gctggattgc agggtgaatc tgattcgttt tcatgccatt
     3001 cccggggtag acctcgaggg ggcggatatg gatacgatga cccgttttcg tgattatctg
     3061 acatcacacg gaattttcac cactatccgt tcatccaggg gcgaagatat ttttgccgct
     3121 tgcggtatgc tgtcgacagc gaaacaagag aaaaataatg aaagttaata tataaaaccg
     3181 aacatcatga aaaagtactc ttttatttta tgcatcgctt tggtagcctt tgtcgttgca
     3241 tcttgtggtc tgaaaggaaa tcacacctct agtggtcgtg cttatgagct tttggttgta
     3301 gtagatcacg gtgtttggga tcgtgctgcc ggaagggctt tacatgatgc gctcgatgct
     3361 gatatgcccg gtttgccgca gtcggaacct tctttccgga ttatgtatac ttcgccgaaa
     3421 gattatgatt ctacactgaa gttgatacgt aacattatta ttgtagatat acaggatata
     3481 tatacgaaag cctcgttcaa atatgcgaag gacgtgtatg ccaatccgca gatgatattg
     3541 actatccagg ctccgaacga agaagagttt gagaagtttg tggaagaaaa caaaaaggtg
     3601 attgtcgact tctttacccg tgcggaaatg aaccgtcaga ttatgcttct tgaagggaaa
     3661 cacagtaatt tcgtttcgca gaaagtggac agtttgttcg gatgcgacat ttgggtggat
     3721 gccgaactgg tcagttcaaa gaccagggat gatttcttct gggcttctac caacacgggt
     3781 agtgccgacc gtaactttgt gatgtactct tatccctata ctgacaagga tacgtttacc
     3841 aaagaatatt ttgtgcacaa acgtgactcc gtgatgaaag ccaatatccc cggattcaag
     3901 gagggcgttt atatgtcgac cgatagtttg ctgaccgatg tccgtccgat caatgtaaag
     3961 aacagctaca caatggaagc acgtggcctg tggcgtatga agggtgactt tatgggtggt
     4021 ccgtatgtat ctcatactcg tctggacgag aaaaaccaac gaattattac agcagaaata
     4081 tttgtttatt cacctgataa aatgaaacgc aacctggtac gccagatgga agcatctctg
     4141 tatacactga aacttccgaa tgaaattcag cagagtcaga ttccattggg aggagaagta
     4201 tctaaggaag cggaacaaac taataaataa aaacatggaa gataacaaga taaggatagg
     4261 tatcacccag ggagatatta acggggtggg ctatgaggtg attcttaaga cattttctga
     4321 ccctatgatg ttggaactat gtactccgat catttacggc tcaccgaaag tagcggctta
     4381 tcatcgcaaa gcgttggata tacagaccaa tttcagcatt atcaactctg ctaccgaagc
     4441 ggtatgcaac cgtttgagcg tggtgaactg cacggatgat gaggtgaaag tggaattttc
     4501 caaacttgac cccgaagccg gtaaagctgc gctgggggct ttggaacgtg ccatcgaaga
     4561 atatcgcgaa gggttgatag acgttatcgt aacagctccg atcaacaaac ataccattca
     4621 gtcggaagag ttttcattcc ccggacatac ggaatatatc gaagaacgtc tgggcaatgg
     4681 tggtaagtca ttgatgattt tgatgaagaa tgacttccgg gtggctttgg tgacgacaca
     4741 tatccctgtc agagagatcg cgactacgat taccaaagaa ttgattcagg agaaactgat
     4801 gatattccat cgttgtctga aacaggattt cggtatcggt gctccgcgta ttgcggtgct
     4861 ctctctcaat cctcatgccg gagacggtgg tttgttggga atggaagagc aggaggtgat
     4921 tatccctgcc atgaaagaaa tggaagagaa aggaatcctt tgctacggtc cttatgctgc
     4981 cgacggcttt atgggttcag gcaattatac tcattttgac ggtatcctgg cgatgtatca
     5041 cgatcagggg ttggctccgt tcaaggcctt ggctatggaa gacggggtga actatacggc
     5101 aggactgccg gtggtacgta cttctccggc tcatggaacg gcatacgata ttgcaggcaa
     5161 gggagtggct tgtgaagatt ctttccgtca ggcaatctat gttgccatcg acgtgttccg
     5221 taatcgtcag cgtgaaaaag tggctcgtgc caatccgttg cgtaaacagt attacgagaa
     5281 acgtgacgat agtgataaac tgaagctgga tacagtagac gaagattaaa aacgagtgat
     5341 gatgaaagca gagatacaac aagtgaaaca gcgtttcggt attattggaa atactgaagc
     5401 attgttgcgc gctatagatg ttgccattca ggtagctcct accgatttgt ctgtgctgat
     5461 taccggagaa agtggagttg gaaaagaaag ttttccgcag attattcatc aatatagccg
     5521 gaggaagcac ggacagtata ttgctgtcaa ctgtggcgct attccggagg gtacgattga
     5581 ttccgaactg ttcggacatg agaaaggtgc gtttaccggt gcgattggcg aacggaaagg
     5641 gtactttggc gaagccgatg gtggtactat ttttcttgat gaagtagggg agttgccgat
     5701 gtctacccag gcacgtttgc ttcgtgtact ggagagtggc gagtttatga aagtaggttc
     5761 gtccaaagta caaaaaacgg atgtgcgtgt agtggcagct accaatgtca atctgacaca
     5821 agcgattgca gacggacgtt tccgtgaaga tttatattac cggttgaata cggtgcctat
     5881 ccagatacca cctttgcgtg aacgtggtga cgatgtactc ctgttgttcc gtaagttttc
     5941 cgcagacttt gcggagaaat accggatgcc tgctattcag ttgacggagg atgcgaagaa
     6001 agagttattg gcttactcgt ggcccggaaa cgttcgtcag ttgaagaaca tcaccgaaca
     6061 aatatctatc attgaaacca acagggagat ctctgctgct atcttgcaga attatcttcc
     6121 tgtacaaaat acgcaacgtc ttcccgcgct gatgggaacg cgtgaaagta aaggctttga
     6181 gagcgaacgg gagattcttt attctgtttt gttcgatatg cgtcaggaag tggcggagct
     6241 gaagaagatg gtgcacaacc tgatggcgga acgtgccgga caggtagggc aggtaggaca
     6301 aatgggaacg gtggttacta ctccggtagt gacggcgcat caaccttcgg tacctgctat
     6361 cattcacacc atgcagccta cggtttgcaa ggatgatgat gacatacaag acacggaaga
     6421 atatgtagaa gaatctccgt tgtcactgga cgaagtggag aaagaaatga tacgcaaagc
     6481 acttgagagg catcatggaa agcggaagag tgctgccaag gacttgaata tttccgagcg
     6541 tacactttat agaaaaataa aagaatatgg attggattaa gaaaataata cgccctttgt
     6601 tactgttcgg cttgccgttg gtagtcattg cgtgcactgt ttcctataag tttaacggat
     6661 cgtctatcaa ttacgataag gtaaagacca tttcgatagc cgacttcccg atcaagtcgg
     6721 agtatgtgta tgctccgttg gcaaccaagt tcaatgagga cctgaaagat attttcatcc
     6781 ggcagacccg tctgcaactg ctcaagccga atcagaatgc cgacttgcag attgacggag
     6841 aaatcacggg ttacaatcag tacaaccagg cagtatctgc cgatggttac tcttcggaga
     6901 cgaagttgac tatcaccgtt aatgtacgtt ttgtcaacaa caccaatcat gccgaagact
     6961 ttgaacaaca gttttctgcg ttccgtacct acgactctag ccagttgctg actgccgtac
     7021 aggacggatt gattgctgaa atgtctaaag agatcactga ccaaattttt aatgcaactg
     7081 tagcaaactg gtaatataaa tgacttctgt taactttcaa caatggattc agcatcccga
     7141 gacgctgaat agggatactc tgtacgaact gcgcaatctt cttgcgaggt atccgtattt
     7201 tcaatcactt cgtctgctgt atctgaagaa cctgtatatt ctccatgata ttagtttcgg
     7261 tggagaactg cggaaagcag ttctttacat tgcagacaga cggcagttgt tccggttgat
     7321 tgaaggtgac cgctatgatg tgcaggcacg gaaaaaggga gtacctctca cggaggtgct
     7381 gaaagacgaa ccgtctgtag accgcacatt agcattgatc gacgctttct tgtccacagc
     7441 ccccgaagaa gtgactgccc ggaccagctt cgactattcg atggattaca cctcttatct
     7501 tttggaggag actccggctg cggaacagcc ggtcgaagaa acgcccaaac tcaaaggcta
     7561 cgaactgatt gacgacttta tagaaaagag cgagagcgat tctcccttct gcaagaaacc
     7621 tttaagagaa gaaatgccat cttcgccaac ctcttcgaac gagccaaccg aagaagaaac
     7681 aatgaaggaa gaagaggaag atgacagctg ttttacggaa actttggcaa aaatctatgt
     7741 taaacagcaa cgatattcaa aagctcttga aataattaaa aaattaagct tgaaatatcc
     7801 aaaaaaaaat gcttactttg cagaccaaat cagatttttg gagaaattga ttattaacgc
     7861 taattcaaaa taactaaaaa tgtacttatt attcgttatc ttaatggtta ttgcagcctt
     7921 gttgatgtgt ttcatcgtgc tgattcagaa ctcaaaagga ggcgggcttg cttctggttt
     7981 ctcttcatct aacgccatca tgggtgtgcg caagactaca gattttctgg aaaaagcaac
     8041 atggggttta gctatcttca tggtggtaat gagcattgct actgcttatg taattcctag
     8101 ttctgatgtt gctaaagacg cagtgttgga acaggcacag aaagaacaac agactaaccc
     8161 gtataactta cccgcaggta cggctgcacc gcaaacaaac gcagttcagc aggattctgt
     8221 taactaagtt ttgttacgag tctaaaaaaa tattgtggtt aaatccgttc aaaagagatg
     8281 tgggtattgc ttgcatctct tttttattaa cataaaacaa aaaaaactgt gaaaacaaca
     8341 ttaagagatt cggcagcgat gcgatggacc gtattgctgt ttctggcgtt tgccatgttc
     8401 tgttcataca tatttatgga catactttct cccattaaag atttgatgca atccacacgt
     8461 ggttgggact ctaccgcctt cggtacgatg cagggttcgg aaactttctt gaacgtattt
     8521 gtattcttcc ttatttttgc gggaatcatt ctcgacaaga tgggcgtgcg ttttacggct
     8581 gttttatcgg gtgtggtgat gctggtcgga gcggttatca actggtatgc cgtgactacc
     8641 gcctttgccg gaagcgatct ggagacttgg tttaataaca atctcaatta tattccggtg
     8701 ttcgatgaac tcggtatttc tcctttctac agggggatgc ctgcatcggc aaaactgtct
     8761 gctgtgggct tcatgatatt cggttgtgga gttgagatgg caggaataac cgtttcacgc
     8821 ggtattgtga agtggtttaa aggtcgcgag atggcgttag ctatggggtc ggagatggca
     8881 ctggcacgct tgggagtggc tacatgtatg attttctcac cggtgtttgc caagttaggt
     8941 ggtgtcattg atgtatcccg ttcggtagct ttcggagttg tattgttgat gatagcacta
     9001 atcatgttca ttgtttactt ctttatggac aaaaaactgg atgcacaaac cggtgaagcg
     9061 gaagagaaag acgatccgtt taagattagt gatttgggta cgattcttaa aagtagcggt
     9121 ttttggttgg tggcgttatt gtgcgtgctt tactattcag ccattctccc gttccaaaag
     9181 tatgccgtta atatgttgca gtgtaatctg acgtttaccg aagtgtcgcc cgattctttt
     9241 tgggctacca atacggtgac tattattcag tattgcatca tgttggtggt ggctgctgct
     9301 gcgtttgcca gcaacttctc gaagagtaag aatttgaaat cggggctgtt gatgttggcg
     9361 gtggtagctt tggtggtgtt ctgttatatg gggtatatgc gtcagagtgc agagacggta
     9421 tttgccgtat tccctctttt ggctgttggc attacgccga ttttgggtaa ctatgtagat
     9481 cacaaaggaa aagcggcgtc catgctggtc atgggatctg tgctgcttat cctctgtcat
     9541 cttacttttg cattcgtgtt gcctggtttc aaaggcaatc cggtgggtgg aatcatcgtt
     9601 gcttacctca ctatcctggt gttgggagcc agtttctcgt tggttccggc ttctttgtgg
     9661 ccgagtgtgc cgaaattggt ggatgcaaag attatcggta gcgcgtatgc attgatattc
     9721 tggatacaga acatcgggtt gtggcttttc ccgttgctta tcggtaaggt gctcgaccgt
     9781 acgaatccgc aacttgtcag cgatttgaag aatggtgtga ttactcccga agaggcggct
     9841 actgcatatg actatacggc accgttggtg atgttggcat gtcttggagg ggcggcactg
     9901 attcttggtt tcgtgcttaa gatagtcgac aagaagaagg gttacggact ggaagaaccc
     9961 aatataaaag aatgatgtta tatgtaataa agaaaaactg atggctgcta aagagaagat
    10021 caacctgtta gaggtcattc cctgtcgcag tgaacatatt acagcaaaaa gggaagggga
    10081 gacaatggtg ctctcctttc ctcgttttaa atatccgtgg atgcaacgct tccttgtgcc
    10141 gaaaggaatg tcgaaagaac ttcatgtaca attggaagaa cacggtacgg ctgtatggga
    10201 actgatagat ggaaaacgca atgttcgtga gattatagaa aaactcgcag accactttca
    10261 aaatgaagag ggctacgagt cgcgtgtatc ggcttatctt tctcaaatgc agaaagatgg
    10321 atttataaaa ctggtgatac cagtcgcata aataggaatt atcatttatt tgataaatac
    10381 agcccaaagt atgacggcaa ttgctatcag gacccccatg ataataagcg ttccccaaac
    10441 aaaataattg ctgtctttct ctttcttttt ctccgagtcg tggatgatac gttccatttc
    10501 ttcgggagtg gtgttgggta atggataagg ttcgttggtg cggtttagat gcttcaactt
    10561 atcgttagca cgttcacgac gtaggcggga agcttcccgt ccttcactaa gccgacgtat
    10621 catgtcgagc atatatcctt caccacccat attctttgtt ttttagaagt ttagttcctc
    10681 gtttttctat ttcccttctt ctctgtccac tttgagcaat cctcccgtat tcggatcaaa
    10741 ataaactttg atggtagaat tcttgttgaa caaaaccgga gccagatatt ctatcacacc
    10801 gaattgagta ataggaagct caccttcgta aagtttcttt ttaccatcgg tcagtgtaac
    10861 cagagcttgt ccgggcacgt tgtaggcgat tccatccaaa tctttcttct tcttaccgtc
    10921 ttcctgtggt atcttgaccg atttcaggtc tttcagactg atataaaacg gagttcctgc
    10981 caaatcatgg ttggcaacta cacctaactt cttcgagaag cggaaggcaa cttcattgtt
    11041 gaattccttg tcaggagtaa ggcggacggt gaatgttctc tcttctttgt tgcaggtgcc
    11101 ggagaacatt tgtgtcatgg cttcttcctg tgcattcagg ttgtcgagca taattttaag
    11161 ctgtgctccg tctgaaggca tattgtcagc ctgtccgcgc aataaggcat ttttgctttc
    11221 gcggatgtta tagatctctt tagccaccag ctcggccatc ttagcggtag agctggccat
    11281 tagaatctct tcggtcagga attcgcgagg atttgctttc ttttggagga ctgcgggagc
    11341 gggagcagtt tttttgcctg cactgctgtt gctgtaagga acattgatcg ttttcacaat
    11401 gccatcctct gtcagttcca tgagcggtgc tactgtctta tccttcaatt ttacgaaata
    11461 cgtagtttcg ctgttgggca cacctacgga tttcactttt acgctagcca gttcccaata
    11521 ctcttcagag ttggcggaga cgttagtcag tcgcaggtaa cgatcagcat atttgctgaa
    11581 ttctccggga gtatagttga ctttgttagc ttttatttca agttctatta gggttttggg
    11641 aagactgtaa accactccat agtcttttcc ctgggtaact cccgtcagta cttcggtttg
    11701 cgcataggcg gacgttgtca taagtagtcc tgctgctata atcaactttt tcatattcgg
    11761 ttctttttta actggttttg aaaacaaagt taatgaagtt attgaaaaaa ggggaagttc
    11821 ttaactttta ttcgcttaca agtcgccagg ctgtcggcag acaggtgata atatcgctgg
    11881 ctatcagtcc aatcattcct tgtttctttt gagcgacatc gcccgccaat ccgtgaatgt
    11941 acgtgccgat tttagcggct tcttcggtgg gataaccttg ggcgagcagc gccaagatta
    12001 ctccggtcag tacgtcaccg ctacctccgg ttgccattcc cggatttccg gtcgggttga
    12061 agaaacattt accttcggga gtgatgatgg cggagtaggc tccttttaag ataatgtgga
    12121 catgggcggt acgcgccagt tcgcaagcct tcatcagacg ttcgtaagag tcttggcatt
    12181 tgccggtcag acgttccagt tctttcggat gcggggtgag gatggaaccc ttcggcaggt
    12241 gggtaagggc atggcggtgg ttggcgagga tattaagagc gtcggcatcc actacaacag
    12301 gagtctggca atgttccagt tgctccaaca aggcagcttc cgtttcctcg tttcgtccca
    12361 gtcccggacc gatgccgact gcttgatagt cgtccgtgtc ggtcggtacg gcaaaacagg
    12421 tttcgttgat gtcggtttct acgattgctt cgggtatgga ggtctgcaag atgtcgttgt
    12481 tgcacatggg tgcatgaaca gtcagcaacc ctactcccga acggaggcag gcgcgggcag
    12541 cgagaacaga ggctcctgcc attccttttg aaccggcaat caatagtgca tggccgaagt
    12601 ttcctttgtg ggcaaactgt ttgcgtggct tgatgagtga acggatttcc tctatttcca
    12661 acatttcgta gttcgtttcc atctcttcaa tgccgtcttc gctcaattgg atgtccagca
    12721 cttcccattc tccgacaaat tccgtgttct ctgcgaaaag aaaggcgagc ttcggcagtt
    12781 gcagactgaa agtcacatcg gcacggataa tattagcttt tacgttgaat gtattttctt
    12841 ctcccatcag tccggaaggg atgtcgatgg ctactaccat ggcaggagag gaattgatgt
    12901 atttcactac ggcagcgaat cctccgctca acggtttgtt cagacctgaa ccgaataatc
    12961 cgtcgattac cagatggtcg ggcgtcaggg cgggaggtac gaattgagtg ctgatttcgt
    13021 ggaattttat ttcttccatc atttctacca gttctttatt ggtctggcag tcgggtgaaa
    13081 gttctccttt cgtgttgaag agaaatactt cgattttata tcctttttca gccatcatgc
    13141 gggctacggc gagtgcgtct ccgccattat tccccggtcc ggcaaagata gtgaccggcg
    13201 tttccgtatt ccatctgtct gtgatggctt ttgttaatgc ggttgctgca cgttccatca
    13261 gatcgattga tgcaataggt tcgttctcaa tggtataagc gtccaatttc ttgatactgc
    13321 tgcttggaaa tattttcatt gcgatgttct tttagttttc ggattacaaa tgtacatgat
    13381 tcttctgact tttcccgttt gttgtgggaa gaaaaccatc tttacaggca tttatttctc
    13441 aggctttcct gcgaaagatt tcttcattgc atttctcata ttctcatagt ttttagataa
    13501 atggaagata atcaaataga tatcttatga gaaacacttt tccaaaacgg tgtttctcat
    13561 aagttttctc ctattttagc tcaaaatcca ccttattctc atagtgtttc agggtatttc
    13621 tcatagtcaa attggataaa ataacggctt cttgcttgaa gatgctcctt agttccgatt
    13681 gtcccatata ttgtgggaaa gtattcccgc gtattaagag aaaactttcc cacaaaatga
    13741 gggaatattt tcccaagcac tagggaatac tttcccaagt agtagggaat cttttcccat
    13801 aatatgtggg actaagccac tgtgtatgga agcaagcaaa aggaatgcat gattctattt
    13861 attcaatgcc cgcttccggc acactacact atgagaaatg aaaatgaaaa aacaatgtag
    13921 tggatcatca ggatttatgc tgtttgataa gaactttctt tttttgggga agcatctaat
    13981 ctactttttc tgtaccttct ctcaaagaaa ttacagaaga tgatgcacga ggtagaataa
    14041 aaaatcgtat ttttgcaagg ttatttttaa attaccggtt atggatacca ttcagataaa
    14101 agacaaattg tttaccgttt ctattaagga acaagatatt cagaaagaag tgattcgcgt
    14161 agcgaacgaa attaaccgcg atttggcagg taagaatccg ctttttctta gtgtgttgaa
    14221 cggttcgttc atgtttactg ctgatttact gaagcacatc accatccctt gtgaaatctc
    14281 atttgtgaag ttggcgtctt atcagggcat cacttccacc ggagtgatta aagaggtaat
    14341 cggcctgaat gaagacattg ccggacgtac cattgtaatc gtagaagata tcgtagacac
    14401 aggactgacg atgcagcgac tgctcgaaac attaggtaca cgcaatcccg aagctatcca
    14461 tatcgcttct ctgttggtga aacctgaaaa gctcaaggta aacctcaaca ttgaatatgt
    14521 cgcgatggaa atcccgaacg actttatcgt aggttacgga ctggattatg atggtttcgg
    14581 acgtaattac cccgatattt atacagtagt agattaatgt taaataggta ccagtttaaa
    14641 tggtaaatag taaatcgtta aattgtaaat aacaaaatgt tgaacatcgt aattttcggt
    14701 gctccgggtt caggaaaagg aacacagagc gaacgtatcg tagaaaagta tggaatcaat
    14761 cacatctcga caggagatgt attgcgtgct gaaatcaaga atggcacaga actgggtaaa
    14821 acagctaaag gttacatcga ccaaggccaa ttgattcctg atgaattaat gattgatatt
    14881 ctggcaagcg tattcgacag cttcaaagat agcaaagggg taattttcga cggtttccca
    14941 agaacaattg cacaggcaga agcattaaag aaaatgttgg cagagagagg acaggacgtt
    15001 tctataatgc ttgacttgga agttcccgaa gaagaactga tggtacgtct tattaaacgt
    15061 ggcaaggatt ccggtcgtgc tgatgataac gaagaaacaa tcaaaaaacg tctgcacgta
    15121 tatcattcgc agactgctcc actgatcgac tggtacaaga acgaaaagaa ataccaacac
    15181 atcaacggct tgggtactat ggaaggtatc ttcgctgaaa tctgcgaagc agtagataaa
    15241 ttgtaataat acaatattat aaataaataa gtcagtagcc ggagtgtgct aattaacagc
    15301 tctgactact gactacttta actcttaaaa aaatatggct gaatcgaatt ttgttgatta
    15361 cgtaaagata tactgtcgct cgggtaaggg cggaagaggc tctacgcaca tgaggcgcga
    15421 gaaatattgt cctaacggag gtcccgacgg gggcgatggt ggcagaggag gtcatatcat
    15481 cttgcgcggt aaccgtaatt actggacatt gctgcacttg aagtatgacc gtcacgcaat
    15541 ggccggtcat ggtgaatcgg ggagcaaagg acgtagtttc ggaaaagacg gtgcggataa
    15601 aataatagaa gtaccctgcg gaacagtagt ttataatgcc gagacagggg agtatctttg
    15661 tgacgtaaca gaagacggac aggaagtgat tttactcaaa ggcggtcgcg gcggtctggg
    15721 taactggcat ttcaagacgg caacccgcca ggctccgcgt tttgcgcagc cgggagagcc
    15781 gatgcaggaa atgaccgtta tcatggagct gaaactgctt gccgatgtcg gtctggtagg
    15841 tttcccgaat gcgggaaagt caactctgct ttcttccatt tcggctgcca aaccgaaaat
    15901 tgccgattac ccgtttacta cgctcgaacc caacttgggc atcgtttcct atcacgatgg
    15961 aaaatccttt gtgatggcgg acataccggg tattatcgaa ggagccagtc agggaaaagg
    16021 tttgggactg cgtttcttgc gtcatatcga acgtaattca ttactgctgt ttatggttcc
    16081 ggcagacagc gacgacattc gtaaagaata cgaagtcttg ctgaacgaac tgcgtacctt
    16141 caatcctgaa atgttggaca agcaacgtgt gttggccatc accaagagcg atatgctcga
    16201 ccaggaattg atggacgaga ttgaacctac actgcccgaa ggcataccac acgtattcat
    16261 atcttctgtt tccggtttgg gcatctcggt attgaaagac atcctttggg aagagctgaa
    16321 caaggaaagc aataagatag aagctatcgt tcaccgtccg aaagacgtga cccgcctaca
    16381 acaggaactc aaagacatgg gcgaagatga agacatcgtt tatgaatatg aggaagatgg
    16441 tgacgatgat atcgattatg aatacgaaga agattgggaa gaagaatgat ttctcttaca
    16501 aaacataacg agttgaaggg atataagtca ttagatgcat atcccgaagt agctcatttc
    16561 gtaactacac gtcacggagg tataagcacc ggagcttacg gctctttcaa ctgttcgcct
    16621 tataccaacg actcatgtgt gaacgtcaat cgcaatcagg actggttgtt tcagtgcatg
    16681 aatcatcaga taaaggaatt atttattcct gaacagagtc atggttgcgc cagtctgatt
    16741 atcaatgaat cattttttaa agaatcattg gaaaggagac ggctacttct gcgaggaatg
    16801 gatgctttga taacgaatgt gccgggatat tgcgtttgtg tcacgacagc ggattgtgtt
    16861 cctgtattgc tgtacgacaa aaaacaacac gttgtggctg ccgttcatgc cggatggaag
    16921 ggaacggtga agcatattgt cagtcatgtg atggaccaca tgactcaaaa gttcgggacg
    16981 taaggcgaaa atgtaatagc ttgcatcggg ccgagcattt cgctcgaatc atttgaagta
    17041 ggcgatgaag tgtatgatgc ttttgaagaa agcggcttcg atatgtctct tatttctatg
    17101 aagaagaagg agacaggcaa atatcatatt gatttgtggg aagccaaccg gattgaatta
    17161 ctgaatcgcg gagtgcctgc agagcagata gaagtggctg gaatctgtac ctatattcat
    17221 catgatgaat tcttctccgc acgtagactg ggaatagatt ccggtcgtat attgtcggga
    17281 ataatgatta gaaagtaata attagtgtcc gtaatcgcag gacgctgatg attggtttat
    17341 gataagttat gtttgaaata aaagtatcta aagaaataaa agacgcatgc ccggtttttg
    17401 ccggagccgc cgtgtatgct gcggtgaaga atactgctta caacgaaggg ctttggcagg
    17461 aaatcaacgc ttttgccggg caactgactt ccactacaca gatggaagac atcaaacatc
    17521 aacctgttat ctttgctacc cgtgaggctt ataagcgttg tggcaaagat cccggacgtt
    17581 atcgcccgtc agccgaagct ctacgccgcc gcctgatgcg tggaatcccg ttatatcaga
    17641 ttgatacgtt ggtagacctt atcaaccttg tgtctcttcg cacgggacat tcgatcggtg
    17701 gttttgacgc ggacaaaata caaggtacgc atcttgaact cggtatcggc aaagcaggag
    17761 aaccgtttga aggtatcgga cgcggtgtat tgaatattga aggattacct gtatatcgtg
    17821 attcttttgg cggaattgga accccgacaa gcgatcatga acgtacgaaa atggatctcg
    17881 gaaccactca tatcctagcc atagtcaacg gttataacgg aaaagaaggt ttgcaagaag
    17941 cggctgaaat gatacaaacc ttattaagaa actatacaga atcggatgga ggcgaaatcg
    18001 tatgcttcga ataattagaa tgagtgctct aagaaaaaag acatgaaaaa catacttatc
    18061 ttactgacag ttttattatt attgccactg actgccgacg ggcaggataa atcctccttc
    18121 tctgcccgcg aaatggctga tgtacgggta gctactcccg gattatttgc taaaggcaat
    18181 catatctatc tgcatttgga ttctctgaaa gatcacgaat atgctttccc attacccgga
    18241 ggaaaagtaa tctctgccta tggaactcgc ggaggacatt cgggaacaga cattaagacc
    18301 tgtgcaaaag atacgattcg tgctgctttt gatggagtgg tgcgtatgtc gaaaccctat
    18361 tatgcctatg gaaatatcgt tgtaatccgc cacgccaacg gattggaaac gctttatagc
    18421 cacaatttca agaatctggt taaagctggt gatgtcgtaa aagccggaca agctatcggg
    18481 ctgacaggac gtactggtcg tgccactacc gaacatgtac acttcgaaac ccgtattaac
    18541 gggcaacatt ttaatccgaa tctcattttt gactttaaag agagaacatt gcggaaagaa
    18601 tgtatcaagt gtaccaagaa cgggagtaaa atcgttgtga gaacgcatac tcctgatagc
    18661 tgggttgctc agagtaagaa gtaattaaat ataaaatagc ttcgtaaaga taacgctttg
    18721 atataatatt tgctaacgtt ttctcgttaa ttagaaaata tttcctatct ttgcactctt
    18781 ggaaaagagt tctaaaacaa tcgctattct gtacgaataa aaatttgggc ttgactggat
    18841 ttgacagcgg gcagaaatgg taggtaagca tgcagtgggt cggtaatttc cacttaaatc
    18901 tcagttatca aaattttatc tggcgaaact aattacgctc ttgctgctta atcgaagtat
    18961 agtagattag cttaatccag gcactaggtg ccaggacgag acatcactcg gaagctgttg
    19021 ctccgaagca ttccggttca gtggtgcagt tacatcgggg atagtcaaag gtggcctcgc
    19081 gcttttgatg aaactttaga ggataaggta ggaattgatg gctttggttc tgttcctgca
    19141 cgaaaaatta ggcaaagata agcatgtaga aagcttatga tttcctcgtt tggacgaggg
    19201 ttcgattccc tccaggtcca caataaatgc tgatttttag tgttttatga gatttgcacc
    19261 ccgctttgca ttctaataat gtaaagcggg gtgttgactt ttccgcccca acctaatctt
    19321 ttttggtggt atcgaatgaa gttccccaat ttccaatagt ggaacagcat ttgtgcattg
    19381 gctgcaacaa tcaattgcac ttgtgcatgt tttatctcaa agcctattgc atgaatgagg
    19441 gcttcaaagt cttttctttc tctcatcagg gagacaattc ctaccttcca gcttttttct
    19501 tctcttacaa ttccggggac aatacaaatg gtctgtgatc cgcataagct tgatatatac
    19561 cattgaaaaa agaattaggg ccaaaagaaa cgagactgtc gggagattcg ctctttgcaa
    19621 tgatatgata aggaaccttg atattcttct cttttatctc ataaggctct atatccatat
    19681 ctgataatat aagactttcg taaatttcat tcggggagtg tagatgaagt aattcttcag
    19741 gctttgaaag cttttcaacc ttaaaagtga ttccattttg agcgaatgtg gaaacactgc
    19801 aaaagataaa taagcaaaat aatgtgtttt tcataatctt aaagagttgt atggtggcac
    19861 aaactaatta actacctcta tattttgaat agacgatatg caaatatagt attattaaga
    19921 actatctttg ataagatatt gaatgttttt tgacttatat ctataaaaat cataagcata
    19981 ttatttcttg aaccgataag taggatttat tcgggaattt atagtaagtt tgctctgcta
    20041 attctaaaca atgacgcaga gaaaaattat acatatcgac atggatgcct tctatgcctc
    20101 tgtagaacag cgtgataatc ctgaacttcg tggcaaacct ttggcggtag gtcatgctga
    20161 agagagggga gttgtggctg ctgccagcta tgaagcccgg cgttacggtg ttcgttctgc
    20221 catggcttcg caaaaggcga aacgtctttg tccccaactc atttttgtac ctggcaggat
    20281 ggatgtttat aaatccgttt cctgtcagat acatgagatt ttccacgaat atacggatat
    20341 catcgaacct c
//
