GCF_001593985.1_ASM159398v1_genomic - 3 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_LTBB01000001 (original name was: NZ_LTBB01000001.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	ranthipeptide	35,549	57,119
Region 1.2	cyclic-lactone-autoinducer	175,794	197,932

NZ_LTBB01000007 (original name was: NZ_LTBB01000007.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 7.1	NRPS	90,794	134,534	locillomycin	NRP + Polyketide	14%

Region	Type	From	To	Most similar known cluster	Similarity
Region 1.1	ranthipeptide	35,549	57,119
Region 1.2	cyclic-lactone-autoinducer	175,794	197,932
Region 7.1	NRPS	90,794	134,534	locillomycin	NRP + Polyketide	14%

No secondary metabolite regions were found in these records:: NZ_LTBB01000002 (original name was: NZ_LTBB01000002.1); NZ_LTBB01000003 (original name was: NZ_LTBB01000003.1); NZ_LTBB01000004 (original name was: NZ_LTBB01000004.1); NZ_LTBB01000005 (original name was: NZ_LTBB01000005.1); NZ_LTBB01000006 (original name was: NZ_LTBB01000006.1); NZ_LTBB01000008 (original name was: NZ_LTBB01000008.1); NZ_LTBB01000009 (original name was: NZ_LTBB01000009.1); NZ_LTBB01000010 (original name was: NZ_LTBB01000010.1); NZ_LTBB01000011 (original name was: NZ_LTBB01000011.1); NZ_LTBB01000012 (original name was: NZ_LTBB01000012.1); NZ_LTBB01000013 (original name was: NZ_LTBB01000013.1); NZ_LTBB01000014 (original name was: NZ_LTBB01000014.1); NZ_LTBB01000015 (original name was: NZ_LTBB01000015.1); NZ_LTBB01000016 (original name was: NZ_LTBB01000016.1); NZ_LTBB01000017 (original name was: NZ_LTBB01000017.1); NZ_LTBB01000018 (original name was: NZ_LTBB01000018.1); NZ_LTBB01000019 (original name was: NZ_LTBB01000019.1); NZ_LTBB01000020 (original name was: NZ_LTBB01000020.1); NZ_LTBB01000021 (original name was: NZ_LTBB01000021.1); NZ_LTBB01000022 (original name was: NZ_LTBB01000022.1); NZ_LTBB01000023 (original name was: NZ_LTBB01000023.1); NZ_LTBB01000024 (original name was: NZ_LTBB01000024.1); NZ_LTBB01000025 (original name was: NZ_LTBB01000025.1); NZ_LTBB01000026 (original name was: NZ_LTBB01000026.1); NZ_LTBB01000027 (original name was: NZ_LTBB01000027.1); NZ_LTBB01000028 (original name was: NZ_LTBB01000028.1); NZ_LTBB01000029 (original name was: NZ_LTBB01000029.1); NZ_LTBB01000030 (original name was: NZ_LTBB01000030.1); NZ_LTBB01000031 (original name was: NZ_LTBB01000031.1); NZ_LTBB01000032 (original name was: NZ_LTBB01000032.1); NZ_LTBB01000033 (original name was: NZ_LTBB01000033.1); NZ_LTBB01000034 (original name was: NZ_LTBB01000034.1); NZ_LTBB01000035 (original name was: NZ_LTBB01000035.1); NZ_LTBB01000036 (original name was: NZ_LTBB01000036.1); NZ_LTBB01000037 (original name was: NZ_LTBB01000037.1); NZ_LTBB01000038 (original name was: NZ_LTBB01000038.1); NZ_LTBB01000039 (original name was: NZ_LTBB01000039.1)

Compact view

c00001_NZ_LTBB.. - Region 1 - ranthipeptide

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Location: 35,549 - 57,119 nt. (total: 21,571 nt) Show pHMM detection rules used

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001387.1	0.18	Other	nucleocidin	Streptomyces calvus
BGC0000684.1	0.11	Terpene	asperthecin	Aspergillus nidulans FGSC A4
BGC0001144.1	0.11	Polyketide	neosartoricin B	Trichophyton tonsurans CBS 112818
BGC0000604.1	0.08	RiPP	GE2270A	Nonomuraea sp. WU8817
BGC0001155.1	0.07	RiPP	GE2270	Planobispora rosea
BGC0001591.1	0.07	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.07	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0000027.1	0.06	Polyketide	ankaflavin, monascin, rubropunctatine, monascorubrin	Monascus pilosus
BGC0001089.1	0.04	Polyketide, NRP	bacillaene	Bacillus velezensis FZB42
BGC0001055.1	0.04	NRP, Polyketide	yersiniabactin	Escherichia coli

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001387.1	0.49	Other	nucleocidin	Streptomyces calvus
BGC0000684.1	0.38	Terpene	asperthecin	Aspergillus nidulans FGSC A4
BGC0001144.1	0.38	Polyketide	neosartoricin B	Trichophyton tonsurans CBS 112818
BGC0000604.1	0.31	RiPP	GE2270A	Nonomuraea sp. WU8817
BGC0001155.1	0.29	RiPP	GE2270	Planobispora rosea
BGC0001591.1	0.28	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.28	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0000027.1	0.27	Polyketide	ankaflavin, monascin, rubropunctatine, monascorubrin	Monascus pilosus
BGC0001089.1	0.20	Polyketide, NRP	bacillaene	Bacillus velezensis FZB42
BGC0001055.1	0.19	NRP, Polyketide	yersiniabactin	Escherichia coli

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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c00001_NZ_LTBB.. - Region 2 - cyclic-lactone-autoinducer

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Location: 175,794 - 197,932 nt. (total: 22,139 nt) Show pHMM detection rules used

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000488.1	0.22	RiPP	circularin A	Clostridium beijerinckii
BGC0001120.1	0.16	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0000552.1	0.16	RiPP	SmbA, SmbB	Streptococcus mutans
BGC0001210.1	0.16	RiPP	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0000539.1	0.16	RiPP	nukacin ISK-1	Staphylococcus warneri
BGC0001765.1	0.15	Saccharide	salecan	Agrobacterium tumefaciens
BGC0000916.1	0.15	Other	molybdenum cofactor	Staphylococcus carnosus
BGC0000548.1	0.15	RiPP	salivaricin A	Streptococcus salivarius
BGC0000294.1	0.14	NRP	acinetobactin	Acinetobacter baumannii
BGC0000794.1	0.14	Saccharide	S-layer glycan	Geobacillus stearothermophilus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000488.1	0.55	RiPP	circularin A	Clostridium beijerinckii
BGC0001120.1	0.47	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0000552.1	0.47	RiPP	SmbA, SmbB	Streptococcus mutans
BGC0001210.1	0.46	RiPP	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0000539.1	0.46	RiPP	nukacin ISK-1	Staphylococcus warneri
BGC0001765.1	0.46	Saccharide	salecan	Agrobacterium tumefaciens
BGC0000916.1	0.45	Other	molybdenum cofactor	Staphylococcus carnosus
BGC0000548.1	0.45	RiPP	salivaricin A	Streptococcus salivarius
BGC0000294.1	0.44	NRP	acinetobactin	Acinetobacter baumannii
BGC0000794.1	0.43	Saccharide	S-layer glycan	Geobacillus stearothermophilus

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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c00007_NZ_LTBB.. - Region 1 - NRPS

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Location: 90,794 - 134,534 nt. (total: 43,741 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001168.1	0.32	NRP	livipeptin	Streptomyces lividans 1326
BGC0001900.1	0.32	NRP	fragin	Burkholderia cenocepacia H111
BGC0001599.1	0.29	NRP	fragin	Burkholderia cenocepacia H111
BGC0001516.1	0.24	NRP	aspergillic acid	Aspergillus flavus NRRL3357
BGC0001399.1	0.22	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0001479.1	0.22	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0000427.1	0.22	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001641.1	0.22	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001132.1	0.22	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.1	0.22	NRP	icosalide A, icosalide B	Burkholderia gladioli

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001168.1	0.65	NRP	livipeptin	Streptomyces lividans 1326
BGC0001900.1	0.65	NRP	fragin	Burkholderia cenocepacia H111
BGC0001599.1	0.63	NRP	fragin	Burkholderia cenocepacia H111
BGC0001516.1	0.58	NRP	aspergillic acid	Aspergillus flavus NRRL3357
BGC0001399.1	0.55	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0001479.1	0.55	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0000427.1	0.55	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001641.1	0.55	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001132.1	0.55	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.1	0.54	NRP	icosalide A, icosalide B	Burkholderia gladioli

Similar known gene clusters

Module view

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Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 90793 - 134534:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg7_122

Search NORINE for peptide: strict or relaxed

AMP-binding (248..657): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAWaaGlVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 70% (weak)