LOCUS       NZ_CP107719.1          10867 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP107719.1 Mycolicibacterium fortuitum strain MF GZ001
            chromosome, complete genome.
ACCESSION   NZ_CP107719
VERSION     NZ_CP107719.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:43:16
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1173752
            Orig. end    :: 1184619
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10867
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1178752:1179619](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5867)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10867
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10867
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="5"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             84..470
                     /locus_tag="ctg1_1084"
                     /transl_table=11
                     /translation="MAGQRNCDSVVNAGRLSKAIEFFEGAEHLGEEMPNAAGDLYVDAG
                     IAASYVLCCVRLGVHSNTGNRSEAVALLKRADSGSERHLNTLLNFKNRAAYTHQDLISA
                     ELKKMNRAAEHLVEAAKQAVAARG"
     CDS             complement(617..964)
                     /locus_tag="ctg1_1085"
                     /transl_table=11
                     /translation="MEHRIFGTAVAAVYPHYLAKIQRKGRTQAELDEAICWLTGFDETT
                     LRNHLEDETTFAEFFADASLNPNASLITGVVCGVKVQEVEDPLMRKIRYLDKLVDELAR
                     GKPMNKVLRTG"
     PFAM_domain     complement(626..955)
                     /aSDomain="DUF2200"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09966.11"
                     /description="Uncharacterized protein conserved in bacteria
                     (DUF2200)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1085_0215"
                     /evalue="6.00E-49"
                     /label="ctg1_1085"
                     /locus_tag="ctg1_1085"
                     /protein_end="113"
                     /protein_start="3"
                     /score="164.9"
                     /tool="antismash"
                     /translation="RIFGTAVAAVYPHYLAKIQRKGRTQAELDEAICWLTGFDETTLRN
                     HLEDETTFAEFFADASLNPNASLITGVVCGVKVQEVEDPLMRKIRYLDKLVDELARGKP
                     MNKVLR"
     CDS             1018..1509
                     /locus_tag="ctg1_1086"
                     /transl_table=11
                     /translation="VTGSVDQIPKATTEWTAQAGDARRATLSILRQPAMWKRLLTFTTV
                     VAAIAAGVCVVNGSGWLVGLVIFAGAAGVYAAFAVAVSLVCAYIPNRRVLRTGSRWAAG
                     GDETRIRIDTPATTLVIDRDNIISVRAAGALIVLRVRPKQVLGIPTALFADPALEGLVG
                     "
     CDS             complement(1532..2335)
                     /locus_tag="ctg1_1087"
                     /transl_table=11
                     /translation="VRSRELVAVVYTAVRVPDAIATLPATPGITYRGMSGPPPRESFTV
                     SAVLPTSADPRIATENFTADRVAAIVTVTGRFVGPLSRHPEEREVAILPGTLLTPVGTV
                     TVTGLTNPVVLLAEPGHAPGLPPGRDELERVVREQVTHALAGPPAPVRSPGRFTPSAGT
                     PVPPADDADVWRLKVFYSTPFGDTKDGRQKLFLLERDGVRYVPVFRSLDSMKAFYERMN
                     RAAYMVLEGDVKTVMDTNRSIELMRSTGIVIDPFGDDPVEIPPTA"
     CDS             2425..3975
                     /locus_tag="ctg1_1088"
                     /transl_table=11
                     /translation="MTDGFLEELEAHAEVRLGLPAANALGMLRDRWVFVGEDHDVLRAL
                     TEQLGKDPEYREFAQRILTLADSRLAAVHEGTEPFVADKAFTAADARVIERAALVALNL
                     DADWAAPIPRILARAAIAPQATAKSAPSQAVAFALARAIMAAPTPESVAGLADTTREVR
                     HAGLKKKFTRYTKEARRAIGGRPDVALRLPFETAPTKAQLTTWTKALEAGWLVGASWPY
                     QTWVDAAFAAPVAPISAGLVWRVVDGPAFLGAPGDFADAEGRPITVPTTARIRLWHPAA
                     AAPAERNAWRLRVRSLQLVQPFAQAFREHYSGADADRLVAAHAVLNVRQLTGLYRAEGW
                     TSEGHETITRRVGAVGAEMWFDSPVYPGSGVETCSAVGLRVGALGMAADGSVTLAAEGS
                     DDAAAVSEILRSADLILSASTVAHDGGASTQSPAGVLATRRVVLEHILAELRSAEPVQI
                     GQRHLVVNGFRISLATGRVTKDGDPVEITPKKRHGVWQPAADRLLTTIVGTVVALLET"
     PFAM_domain     3022..3444
                     /aSDomain="DUF4132"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13569.8"
                     /description="Domain of unknown function (DUF4132)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1088_0216"
                     /evalue="2.60E-19"
                     /label="ctg1_1088"
                     /locus_tag="ctg1_1088"
                     /protein_end="340"
                     /protein_start="199"
                     /score="69.9"
                     /tool="antismash"
                     /translation="KAQLTTWTKALEAGWLVGASWPYQTWVDAAFAAPVAPISAGLVWR
                     VVDGPAFLGAPGDFADAEGRPITVPTTARIRLWHPAAAAPAERNAWRLRVRSLQLVQPF
                     AQAFREHYSGADADRLVAAHAVLNVRQLTGLYRAEGW"
     CDS             complement(3972..4733)
                     /locus_tag="ctg1_1089"
                     /transl_table=11
                     /translation="MVGCALVLGAGAAQADPAPFEPPRLVPADGATVGVAQPIIINFPG
                     PVDDAGATENSIHISSVPEVPGKFYWITPTQLRWRPLNFWPAHTSVTVDAAGTVSNFTI
                     GDALVATANDSTHQLTVTRNGTVEKTIPMSMGMASGGHQTPNGTFYVQEKMPSVVMDSS
                     TYGVPVNSPNGYKLNVDLAVRFDDSGDFVHSAPWSVADQGKRNVSHGCINISPANAKWF
                     FDTVRPGDPIIVQNSGGGTYTRYDGSNDWQI"
     PFAM_domain     complement(4032..4400)
                     /aSDomain="YkuD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03734.16"
                     /description="L,D-transpeptidase catalytic domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1089_0218"
                     /evalue="1.50E-19"
                     /label="ctg1_1089"
                     /locus_tag="ctg1_1089"
                     /protein_end="234"
                     /protein_start="111"
                     /score="70.9"
                     /tool="antismash"
                     /translation="ANDSTHQLTVTRNGTVEKTIPMSMGMASGGHQTPNGTFYVQEKMP
                     SVVMDSSTYGVPVNSPNGYKLNVDLAVRFDDSGDFVHSAPWSVADQGKRNVSHGCINIS
                     PANAKWFFDTVRPGDPIIV"
     PFAM_domain     complement(4401..4667)
                     /aSDomain="Big_10"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17964.3"
                     /description="Bacterial Ig domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1089_0217"
                     /evalue="1.20E-22"
                     /label="ctg1_1089"
                     /locus_tag="ctg1_1089"
                     /protein_end="111"
                     /protein_start="22"
                     /score="81.0"
                     /tool="antismash"
                     /translation="PRLVPADGATVGVAQPIIINFPGPVDDAGATENSIHISSVPEVPG
                     KFYWITPTQLRWRPLNFWPAHTSVTVDAAGTVSNFTIGDALVAT"
     CDS             complement(5001..5867)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1090"
                     /sec_met_domain="DUF692 (E-value: 1e-69, bitscore: 233.2,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTATRTVPALGDVGLGWRREIAGLIADLTPGFCEVIAEAVPMRR
                     RRARPDPMLTTLADAGVPVIPHGVALSLGGADPVQPARVRRLATCAEALGSPLVSEHIA
                     FVRAGGIEAGHLLPVPRTREALEVLARNITRTAAELPVPLAVENIASFVEWPESDLSES
                     EFLTELVECTDVLLVLDVANVYANARNRGLDPQQELARLPVERVAYSHVAGGRQGEDFY
                     HDTHTDRTPPEVLDLVTALRERADVPFMLERDGRYPPAAEMFDELDAIAAAAGAEPITS
                     RARKVWA"
     PFAM_domain     complement(5049..5828)
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1090_0219"
                     /evalue="1.10E-79"
                     /label="ctg1_1090"
                     /locus_tag="ctg1_1090"
                     /protein_end="273"
                     /protein_start="13"
                     /score="267.5"
                     /tool="antismash"
                     /translation="VGLGWRREIAGLIADLTPGFCEVIAEAVPMRRRRARPDPMLTTLA
                     DAGVPVIPHGVALSLGGADPVQPARVRRLATCAEALGSPLVSEHIAFVRAGGIEAGHLL
                     PVPRTREALEVLARNITRTAAELPVPLAVENIASFVEWPESDLSESEFLTELVECTDVL
                     LVLDVANVYANARNRGLDPQQELARLPVERVAYSHVAGGRQGEDFYHDTHTDRTPPEVL
                     DLVTALRERADVPFMLERDGRYPPAAEMFDELDAIAAA"
     CDS             complement(5864..6781)
                     /locus_tag="ctg1_1091"
                     /transl_table=11
                     /translation="MSIEQLMERFATAMTAEANWYLAALVAAAVFAVLWRIITTPRRQA
                     SADPISPTELAFLRSHVAPVVAALAGLRAGGRITGNGRVDRAVPAGAQDDRFTEQTLAR
                     VAADPEHTVPGLYAASGEDLAALEEQLSRRGLLRTQSERSRMRWGVAPSFPILVAGIGY
                     CVYLATHADQHPSYVAPLVVLILATLGYLVGVLPLLLKVDRLTRAGRQLLAAEKARLAY
                     LDPSKRPAFDTYGPAAVALSVALFGTGALWAVDADYSSSVQLAGDSSGGTDGGGCGASC
                     GGDGGGGGCGSGCGGCGGCGGCGG"
     aSDomain        complement(6026..6724)
                     /aSDomain="TIGR04222"
                     /aSTool="tigrfam"
                     /description="near_uncomplex: TIGR04222 domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1091_0036"
                     /evalue="1.60E-32"
                     /identifier="TIGR04222"
                     /label="ctg1_1091"
                     /locus_tag="ctg1_1091"
                     /protein_end="252"
                     /protein_start="19"
                     /score="110.9"
                     /tool="antismash"
                     /translation="WYLAALVAAAVFAVLWRIITTPRRQASADPISPTELAFLRSHVAP
                     VVAALAGLRAGGRITGNGRVDRAVPAGAQDDRFTEQTLARVAADPEHTVPGLYAASGED
                     LAALEEQLSRRGLLRTQSERSRMRWGVAPSFPILVAGIGYCVYLATHADQHPSYVAPLV
                     VLILATLGYLVGVLPLLLKVDRLTRAGRQLLAAEKARLAYLDPSKRPAFDTYGPAAVAL
                     SVALFGTGALW"
     CDS             7123..7689
                     /locus_tag="ctg1_1092"
                     /transl_table=11
                     /translation="VRRGLAAAVLAVTVAFCGLSPAIAHAVPPVAGKDFTKPAIVILGY
                     GLKPDGSMRPILYHRVLTGLAIAQSFPQSPVIVTGGNPRNGQTEAAQMRNLLVMLGFPA
                     NRIIVEDKANSTVQNAQFSVPLAKKAGATGIIVVTSSTHQGRADQNFADAGGNVLATVS
                     FPDGNPSVNIAQFVRDVLSPVTPIG"
     PFAM_domain     7237..7608
                     /aSDomain="DUF218"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02698.19"
                     /description="DUF218 domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1092_0220"
                     /evalue="6.30E-23"
                     /label="ctg1_1092"
                     /locus_tag="ctg1_1092"
                     /protein_end="162"
                     /protein_start="38"
                     /score="81.3"
                     /tool="antismash"
                     /translation="AIVILGYGLKPDGSMRPILYHRVLTGLAIAQSFPQSPVIVTGGNP
                     RNGQTEAAQMRNLLVMLGFPANRIIVEDKANSTVQNAQFSVPLAKKAGATGIIVVTSST
                     HQGRADQNFADAGGNVLATV"
     CDS             8025..8624
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 82.4; E-value: 9.5e-25)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_1093"
                     /transl_table=11
                     /translation="MNSPTTSVEADKSAFRSRLLDAMIQSVVEDGYQNTTVADIVRRAK
                     TSRRTFYEHFASREECFVALLTSVNTKHVREVARGVDQSAPWQAQVRQAVEAWIGSYEA
                     HPELMLAWIRDLPTLGAAARALQRESMENFIAMVQVMTNNEVFRAAGVSISRRRTIMLL
                     GGLRELTAMTVESGGQIGEITEDAVLACTAMLTPLS"
     PFAM_domain     8079..8219
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00440.25"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1093_0221"
                     /evalue="3.20E-12"
                     /label="ctg1_1093"
                     /locus_tag="ctg1_1093"
                     /protein_end="65"
                     /protein_start="18"
                     /score="46.1"
                     /tool="antismash"
                     /translation="LLDAMIQSVVEDGYQNTTVADIVRRAKTSRRTFYEHFASREECFV
                     AL"
     CDS             complement(8617..9093)
                     /locus_tag="ctg1_1094"
                     /transl_table=11
                     /translation="MVSLIVHAVLGVAVVALVIRLNPGIFARPPGPALSAVELAFYVVG
                     LASIPICWYFNMQFVAQYAQPDGNPIWGPGSWQEFIALGYTNPAAGSASADYTIANVIL
                     LPLFTIIDGLRRGIRHPWLFFVASLFTSFAFAFAFYFATIERQRRHQLAEVAVS"
     PFAM_domain     complement(8656..8973)
                     /aSDomain="DEP1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11196.10"
                     /description="Terpene cyclase DEP1"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1094_0222"
                     /evalue="3.80E-25"
                     /label="ctg1_1094"
                     /locus_tag="ctg1_1094"
                     /protein_end="146"
                     /protein_start="40"
                     /score="88.1"
                     /tool="antismash"
                     /translation="FYVVGLASIPICWYFNMQFVAQYAQPDGNPIWGPGSWQEFIALGY
                     TNPAAGSASADYTIANVILLPLFTIIDGLRRGIRHPWLFFVASLFTSFAFAFAFYFATI
                     ER"
     CDS             9183..9788
                     /gene_functions="regulatory (smcogs) SMCOG1215:TetR family
                     transcriptional regulator (Score: 144; E-value: 9.8e-44)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_1095"
                     /transl_table=11
                     /translation="MARPAQTVRSERTREALRQAALVRFLAQGVEGTSAEQIAADAGVS
                     LRTFYRHFTSKHDLLFADYDAGLHWFRAALAERPASESILDSVQSAILAFPYDVDAVTK
                     IASMRAVELDPDRIVRHIRQVESDFADAVAELLVARAGQVPAGDDRLRIVVTARCVAAS
                     VFGAMELWMVGNEAGERSLPELARMCRTALEALRSGLD"
     PFAM_domain     9237..9368
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00440.25"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1095_0223"
                     /evalue="5.20E-11"
                     /label="ctg1_1095"
                     /locus_tag="ctg1_1095"
                     /protein_end="62"
                     /protein_start="18"
                     /score="42.3"
                     /tool="antismash"
                     /translation="QAALVRFLAQGVEGTSAEQIAADAGVSLRTFYRHFTSKHDLLFA"
ORIGIN
        1 cacgaggtgt cgaagcaagg ccagaccgtc gcggggacgc gggcctggtt caacgcgcag
       61 ctgcgcgcgg cgaggaagtc ctgatggcgg ggcaacgcaa ctgtgactcc gtggtcaacg
      121 ccgggcgctt gtccaaggcg atcgagttct tcgagggtgc cgagcatctc ggcgaggaaa
      181 tgcccaatgc cgccggcgac ctgtacgtgg acgcgggcat cgcggcctcg tacgtgctct
      241 gctgcgtgcg cctcggtgtg cactcgaaca ccggcaaccg cagcgaggcc gtcgccttgc
      301 tcaagcgagc ggacagcgga tcggagcggc acctgaacac cctgctcaac ttcaagaaca
      361 gggctgccta cacacatcag gatctgatct ctgcggagtt gaagaagatg aaccgcgccg
      421 ccgagcacct ggtcgaggca gccaagcaag cggtcgccgc ccgcggatag ttcgcgggtc
      481 gtccgcatga tcctccagct caaccagttc tcgaccgccg cgaatccgcc ctgtcggccc
      541 cgatcagggg ccaggcgaca cgacataccg attaccgaga gcgacccgtt cgggatttgg
      601 tcgcctacct ggcgggctac cccgtgcgca gcaccttgtt catcggtttg ccgcgcgcca
      661 gttcgtcgac gagcttgtcg aggtagcgga tcttgcgcat cagcggatcc tcgacctcct
      721 gcaccttgac gccgcagacg acaccggtga tcagcgaggc gttcgggttc agcgaggcgt
      781 cggcgaagaa ctccgcgaat gtcgtctcgt cctcgaggtg gttccgcagc gtcgtctcgt
      841 cgaacccggt cagccagcag atggcctcgt ccagttcggc ctgggtgcga cccttgcgct
      901 gtatcttcgc caggtagtgc gggtacaccg ccgccacggc ggtgccgaag atccggtgct
      961 ccatgcgtcg aggctacggc gtggcggcct ttctgcccgc cgtgccagac ttcgttcgtg
     1021 accggcagcg tggatcagat ccccaaggcc accaccgagt ggaccgctca ggccggcgac
     1081 gcccgccggg caacactgtc aatcctgcgg caacctgcga tgtggaaacg gctgctgaca
     1141 ttcaccacgg tggtcgccgc gatcgccgca ggcgtgtgcg tcgtcaacgg cagcgggtgg
     1201 ctggtcgggt tggtgatatt cgcgggggcg gccggggtgt acgcagcctt cgctgtcgcg
     1261 gtcagtctgg tgtgcgccta catccccaac cggcgcgtcc tgcgcaccgg ttcgcggtgg
     1321 gccgccggcg gcgacgaaac ccgaatccgt atcgacactc ctgcgaccac tctggtcatc
     1381 gaccgcgaca acatcatctc ggtccgcgcg gccggtgcgc tgatcgtgct gcgggtacgg
     1441 cccaagcagg tcctagggat cccgacggcg ctattcgccg atccggcact ggagggcctc
     1501 gtcggctgac gcgactggcg tgcggcgccc ctcacgcggt agggggaatc tcaaccggat
     1561 cgtcaccgaa gggatcgatg acgatccccg tacttctcat cagttcaatc gagcggttgg
     1621 tgtccatcac ggtcttcacg tcaccctcga gcaccatgta ggcggcacgg ttcatccgct
     1681 cgtagaaggc cttcatcgag tccaagctcc gaaaaaccgg gacataccgc acaccatccc
     1741 gttcaagcag gaacagtttc tgccggccgt ccttcgtgtc cccgaaaggc gtggaataga
     1801 acactttcag ccgccagaca tcagcatcgt cggcgggtgg aacgggcgtc cccgccgatg
     1861 gtgtgaagcg accaggggag cggacaggcg ccggcgggcc ggcaagagca tgggtgacct
     1921 gctcgcgcac cacccgctcc aactcgtcac ggccaggcgg caatcccggc gcatgcccgg
     1981 gttcggcaag cagcacaaca ggattggtga gccccgtaac ggtcacggtt ccgacgggtg
     2041 tcagtagtgt gcccggcagg atggcaacct cacgttcctc agggtggcgt gagagcggcc
     2101 cgacgaaccg acctgtgaca gtgacgatcg ccgcgacccg gtctgcggtg aagttctctg
     2161 tggcgatccg tggatcagcc gacgtgggaa gaaccgccga caccgtaaag gactcccgcg
     2221 gcggcggacc gctcatgccg cggtaggtga ttcccggcgt agcgggaagc gtggcaatgg
     2281 catcaggcac tcgcacagct gtgtatacca ccgcaaccag ctcgcgggac cgcacgcgcg
     2341 atcctcctcg agccttgacg gaaccgcccc tgggccagtt tttggcgcgg ttctccgtcg
     2401 ccgcatcgtc gtacgctctg caccatgacc gacgggttcc tcgaggaact ggaagcccat
     2461 gccgaagttc gtctcggatt gcctgcggcc aacgcactgg ggatgttgcg ggatcggtgg
     2521 gtgttcgtcg gggaggacca cgatgtcctg cgtgcgctga ccgagcagct cggcaaggac
     2581 cctgaatacc gtgaattcgc gcagcgcatc ctcaccctcg cggactcgcg actggccgct
     2641 gttcacgagg ggaccgagcc gttcgtcgcc gacaaggcgt tcaccgcggc cgacgcccgg
     2701 gtgatcgagc gcgctgcgct cgtcgcgctc aatctggacg ccgactgggc cgcgccgatc
     2761 cctcgaatac tcgcccgagc cgccatcgca ccccaggcga cagccaaatc ggcgccgtcg
     2821 caggcggtcg ctttcgcatt ggctcgggcc atcatggccg cgccgacacc cgagagtgtg
     2881 gcgggcctcg cggacaccac gcgcgaggta cggcacgccg ggctcaagaa gaagttcacc
     2941 aggtacacga aggaggctcg ccgggcgatc ggcgggcgcc cggacgtcgc cttgcgcctg
     3001 cccttcgaaa ccgcgcccac aaaggcccaa ttgacgacct ggaccaaggc gttggaggcg
     3061 gggtggctcg tcggcgcatc gtggccgtat cagacctggg tcgacgctgc cttcgccgcg
     3121 ccggtcgcac cgatcagcgc cggcctggtc tggcgggtcg tcgacgggcc ggcgttcctc
     3181 ggcgcgccgg gcgacttcgc cgacgcagag ggccgcccga taaccgtccc gaccaccgcc
     3241 aggatccggc tctggcaccc cgccgcggcg gctcccgccg aacggaatgc gtggcgtctt
     3301 cgggtccgaa gcctgcaact ggtacagcct ttcgcgcaag cgttccgcga gcattactcc
     3361 ggtgctgacg ccgaccgatt ggtggcggct cacgcggttc tgaacgtgcg acagctgacc
     3421 ggtctgtatc gggcagaggg gtggaccagc gaaggccacg agaccatcac ccgacgggtc
     3481 ggggcggtgg gtgcggagat gtggttcgac agcccggtgt acccgggctc gggcgtggag
     3541 acgtgcagtg cggtaggtct gcgggtgggc gccttgggga tggccgccga cggctcggtg
     3601 acacttgctg ccgaggggag cgatgacgcg gctgccgtgt cggagatcct gcgttcggcc
     3661 gatctgatcc tcagcgcctc cacggtcgcg cacgacggcg gcgcctcgac tcagtcaccg
     3721 gcgggagtgc tcgccacgcg gcgggtggtt ctcgagcaca tcctggccga actcaggtcg
     3781 gccgagccgg tccagatcgg tcaaaggcac ctggtggtca acggattcag gatcagcctg
     3841 gccacgggcc gtgtcacgaa ggacggtgac ccggtcgaga tcacaccgaa gaagcgccac
     3901 ggcgtgtggc aaccggccgc ggaccgactg ctgacgacga tcgtcggaac ggtcgtggcg
     3961 cttctcgaaa cctagatctg ccagtcgttg gagccgtcgt accgggtgta ggtgccgccg
     4021 ccggagttct gcacgatgat gggatcgccc ggtcggacgg tgtcgaagaa ccacttcgcg
     4081 ttggcggggc tgatgttgat gcagccgtgg ctgacgttgc gcttgccctg atcggccacg
     4141 gaccacgggg cgctgtggac gaagtcgccg ctgtcgtcga accggacggc cagatcgacg
     4201 ttcagcttgt atccgttcgg cgagttgacc gggacaccgt aagtcgacga atccatcacc
     4261 accgagggca tcttctcctg aacgtagaag gtgccgttcg gtgtctggtg gccgccggat
     4321 gccatgccca tcgacatcgg gatggttttc tccacggtcc cgttgcgggt gacggtcagc
     4381 tggtgggtgc tgtcgttggc cgtggccacc agggcgtcgc cgatggtgaa gttggacacg
     4441 gtgccagcgg cgtcgacggt gaccgaggtg tgggccggcc agaagttcag cggacgccaa
     4501 cgcagctgcg tgggcgtgat ccagtagaac ttgccgggca cttccgggac cgacgagatg
     4561 tggatggagt tctcggtggc acccgcatcg tcgacgggcc cggggaagtt gatgatgatc
     4621 ggctgggcca caccgacggt cgcgccgtca gcgggcacga ggcgcggcgg ctcgaacggt
     4681 gccggatccg cctgtgcggc accggcaccc agcaccaacg cacatcccac catcgcagcc
     4741 gctccggccg ccctcaacgc gccgaaaagc ctgcccctcg tccactcagt catctgacca
     4801 tcgtgtcatg ctggtcagac ctgtccagta acgcggccac caccggcgcc gacgagtcgt
     4861 ggcacccgaa tgcgcgtcgc gtttgtgccg gcacacctcg cctgccgcgg ccacggctgc
     4921 cggatcgaaa cccgctggta cgggcccgtc ggcgaccaag gcgcggacca gggcggcttg
     4981 ccgctgggcc aacgtttctt tcatgcccac acctttcgtg cgcgtgaggt gatcggctcg
     5041 gcccccgctg ccgcggcgat cgcgtcgagc tcgtcgaaca tttcggcagc cggcgggtat
     5101 cgtccgtcgc gctccaacat gaaggggacg tcggcccgct cacgcaacgc ggtgaccagg
     5161 tccagcacct ctggcggggt ccggtcggtg tgcgtgtcgt ggtagaagtc ctcaccctgc
     5221 ctgccaccgg cgacatggct gtaagcgacg cgttcaaccg gcagccgggc cagctcctgt
     5281 tgcgggtcga gcccccgatt acgggcgttg gcatagacat tcgccacgtc gagcaccagc
     5341 agcacgtcgg tgcattcgac cagctcggtc aggaactccg actcgctgag atccgattcg
     5401 ggccattcca cgaacgacgc gatgttctcc accgccaacg gcaccggcag ctccgcggcg
     5461 gtccgggtga tgttgcgggc caacacttcc agcgcttccc gggtgcgggg taccggcagt
     5521 aggtgtccgg cctcgatccc gccggcccgc acgaaggcga tgtgctcgct gaccaacggg
     5581 gaaccgagcg cctcggcgca tgtggcgagc ctgcggaccc gcgccggctg caccggatcc
     5641 gcaccgccca gtgacaaggc caccccgtgc gggatcaccg gcaccccggc gtcggcgagc
     5701 gtggtgagca tcggatcggg ccgggcacga cgccgccgca tcggcaccgc ttcggcgatc
     5761 acctcacaga agccgggtgt gaggtctgcg atgaggccgg cgatttcgcg gcgccacccc
     5821 aggccgacgt cgcccagggc gggcaccgtg cgggtcgcgg tcgtcatccg ccgcaccctc
     5881 cgcaaccgcc gcaccctccg catccgcttc cgcacccacc tccgccgccg tcgccgccgc
     5941 aggaggcgcc acacccgccg ccgtcggttc cgccggagga gtctccggcc agttgcaccg
     6001 aactggagta gtcggcgtcg acggcccaca gtgctccggt gccgaacagg gccacggaca
     6061 gcgccaccgc cgccggaccg taggtgtcga acgccgggcg cttgctgggg tccagatagg
     6121 ccaggcgcgc cttctccgcc gcgagcagtt gtcgtcccgc ccgcgtcagc cggtcgacct
     6181 tgagcagcag gggcagcact ccgacgaggt agccgagcgt cgccaggatc agcaccacca
     6241 gcggcgccac gtagctcgga tgctgatcgg cgtgggtcgc caggtacacg cagtaaccga
     6301 tcccggccac caggatgggg aacgacggcg ccacacccca ccgcatccgg ctccgctccg
     6361 actgggtgcg gagcagaccg cgccggctca gctgttcctc caacgcggcc aggtcctcgc
     6421 cggatgccgc atacagaccc ggcaccgtgt gttcggggtc ggccgcgacg cgggccagtg
     6481 tctgttcggt gaaccggtcg tcctgcgcac cagccggcac ggcgcggtcc acccgtccgt
     6541 tgccggtgat ccgtccgccg gcacgcagcc ctgccagggc cgccaccacc ggtgcgacgt
     6601 gggaccgtag gaaggcgagt tccgtcgggc tgatcgggtc cgcgctcgcc tgtcgccgcg
     6661 gagtagtgat gatccgccag agaaccgcga acacagccgc tgcgaccagt gcggccaggt
     6721 accaattcgc ttctgcggtc atggctgtcg cgaatctctc catcagttgc tcgatcgaca
     6781 tcacagtcac ctcctggtgt tcggttctga ccaccctgca ggggctgtgc ccgttaccgg
     6841 tcacaagttt cagtcggtcc tcacgtcgtt cggcccggct gaatcagcca gcgtgcacgg
     6901 cgcgagaaag gagttggtga ggacccattg gctgttgaat gaggaaaatt cgcgccctcg
     6961 gcgtgatctc gaaagccgga gttttcggcg gggatgctca cgaggtggct ggaatgtcac
     7021 agcaggcaca ctgcgcctca tggaccttat ctgtaacatc gccctcagag gcatcgataa
     7081 tcacgcgtgt cgcaattttc tgggtgaacc gggggtgaaa ctgtgcgccg agggttggcg
     7141 gcggccgtcc tggcggtgac ggtggcgttt tgcgggctga gcccggcaat cgcccacgcc
     7201 gtgccgccgg tggccggcaa ggacttcacc aagcccgcca ttgtcatcct gggctatggg
     7261 ctgaagcccg acgggtcgat gcgcccgatc ctgtaccacc gcgtgctcac cgggctcgcg
     7321 atcgctcagt cgttcccgca gtcgccggtg atcgtcaccg gcggcaaccc ccgcaacggt
     7381 cagaccgagg cggcgcagat gcgcaatctg cttgtgatgc ttggctttcc ggccaaccgc
     7441 atcattgtcg aggacaaggc caacagcaca gtgcagaacg cgcagttctc ggtaccgctg
     7501 gccaagaagg cgggcgccac cgggatcatc gtggtgacct cgtcgacgca tcaggggcgg
     7561 gcagaccaga atttcgccga cgcgggcggc aatgtgctgg ccaccgtgag cttcccggac
     7621 ggaaatccct cggtgaacat cgcgcagttc gtacgtgacg tcctgagccc ggtgacgccg
     7681 atcggttgat tgccgcacgg ctaggctggg tttgcaccga tgaaagtgtg acgaccatgc
     7741 ccaggactgt ccggatgtcc cggttgctgg ttgggtgctg ctgcgccgcc gccgtcgctt
     7801 ttgcgccttc tgccctcgct gaaccggcgg cactggatcc gaccgggaac cgttccggag
     7861 ggcctgtccc gacggtcaac ggtgtgccgt gtgtgggcgg caatctcggc gtctgcctga
     7921 gcttccggca gaaccggcca ccggccgcca gcccggtagc acggtccagc gtcggccata
     7981 gccccaccgt gcgtcgctga ccggcattac catggcaggc cgagatgaac agtcccacga
     8041 cgtcggttga ggccgacaag agcgcgttcc ggtcgcggct gctcgatgcc atgattcagt
     8101 cggtcgtcga ggacggctat cagaacacca cggttgccga cattgtgcgg cgtgccaaga
     8161 cctcgcggcg cacgttctat gaacatttcg ccagccgcga ggagtgcttc gtcgcgctgc
     8221 tgacgagcgt caacaccaag catgtgcggg aagtggctcg cggggtcgac cagagtgcgc
     8281 cctggcaggc ccaggtccgc caggcggtcg aggcgtggat cggctcgtat gaggcccatc
     8341 ccgagttgat gctggcctgg atccgcgatc ttccgaccct gggcgccgcg gcgcgggcgc
     8401 tgcagcgtga gtcgatggag aacttcatcg cgatggttca ggtcatgacg aacaacgagg
     8461 tgtttcgcgc ggccggagtg tcgatctcac ggcgccgcac catcatgctg ctcggcgggc
     8521 tgcgtgagct caccgcgatg acagtggaga gcggcggcca gatcggcgag atcaccgagg
     8581 acgcggtgct ggcctgtacc gcgatgttga ccccgctcag ctgacggcga cctcggccag
     8641 ctggtggcgg cgctggcgtt cgatggtggc gaagtagaag gcgaatgcga acgcgaagct
     8701 ggtgaacagg ctcgccacga agaacagcca cggatggcgg ataccgcgcc gtagcccgtc
     8761 gatgatcgta aacagcggta gcagaatgac attggcgatg gtgtagtcgg cactggccga
     8821 acccgccgcc gggttggtgt agccgagcgc gatgaactcc tgccaacttc ccggccccca
     8881 gatcgggttg ccgtccggtt gggcgtactg cgcgacgaac tgcatgttga agtaccagca
     8941 gatcgggatg gacgcgaggc cgacgacgta gaaggccagt tcgacggcgg acagcgccgg
     9001 ccccggcggg cgggcgaaga tcccggggtt gagtcggatg acgagcgcga cgacggccac
     9061 gcccagtact gcatgaacga tgagcgacac catggcgtga gcacactcgc cttccgaagt
     9121 tttgtcaata ttgacatttg gcggctccgg ggatcggcgg gtgatggggt aatttcactt
     9181 gcatggccag gcccgcgcag accgtgcgca gcgagcgcac gcgcgaggcg ctgcgtcagg
     9241 ctgccttggt ccgatttctc gcccagggcg tcgagggcac ctcggccgaa cagatcgccg
     9301 ccgacgccgg ggtttccctg cgtacgttct accggcactt cacctccaag cacgacctgc
     9361 tgtttgccga ctacgacgcc ggcctgcact ggtttcgggc cgcgctggcc gaacggcccg
     9421 catccgaatc gatcctcgac tcggtgcagt cggcgatcct ggccttcccg tacgacgtcg
     9481 acgcggtgac gaagattgcc agcatgcggg cggtggagct cgaccccgat cggatcgtgc
     9541 gccacatccg ccaggtcgag tccgatttcg ccgacgccgt ggccgaactg ctggtggcgc
     9601 gggcgggtca ggtgcctgcg ggggatgacc ggctgcggat cgtggtgacc gcccgatgcg
     9661 tcgcggcgtc ggtgttcggc gccatggagc tgtggatggt cggcaatgag gcgggcgagc
     9721 gatcactgcc cgagttggca cggatgtgcc ggacggctct ggaagcgctg cgatccgggc
     9781 tggactgagt ccgggtccag gaacgacctg ctcaatgttt tgtcattatt gacaaaactg
     9841 cgggcgcggt gtcagcctca gtcgatggcg gactacgacg cgatcgtgat cggcgccggg
     9901 cacaacgggc tggccgcttc ggccctgttg gcccgggccg gtatgcgcac cctgtgtctg
     9961 gaggccgggc gatatgccgg cggtatggcc tcgaccgtgg agctgttcga cggctaccgg
    10021 ttcgagatcg ccgggtcgct gcaatttccc acgtcggcgg tggtcagcgc cgaactcggc
    10081 ctggacacct tgccgaccat cgacctcgag gtcatgtcgg tatcactgcg gggagtcggt
    10141 gacgctccgg tcgtctacta ctccgacccg atgaagatgc tggcccacct gggtgaggtg
    10201 cacggcgccg acgcggtggc tggcatggcg ggcctgatgg cctggagcct ggcgcccacg
    10261 cgagcgctcg gccggttcga cgctgggcgt gggccccgct cactcgacga gatgtatgcc
    10321 tgcgctgcaa cggaatccga gcgtgccgcg atcgacgacc tgctgttcgg atcggtgagc
    10381 gacgtcttgg accgctatct gccggaccgg gacaagcacg gtgcactgcg cggtatgttg
    10441 gcttttctgg cggtcaacac cacctaccgc gggcccgaaa cgccgggcag cgcggccgct
    10501 ttggcctacg gcctggcagt gcccgacgag aacgccatgc tgatgaagaa gctggccggc
    10561 gggatcggcg ctctgaccga acacctgcag acgctgttca ccgccgccgg cggtgaattg
    10621 cgattgcgta gcgctgtcga gcgcatctgc gtcgacagcg ggcggatcag cggcgtgact
    10681 ctggccgacg gtacctcgat caccgcaccc gtcgtcgtat cggcgatcgc cccggatacc
    10741 accgtcaccg aactcgttga ccccgaggtc ctgccggcag aggtgcggga gcggttcacc
    10801 cacgtcgacc accgcggcag ttacctgcag atgcatttcg ccctcgacgg cgcgcctgtg
    10861 ttcgagg
//
