LOCUS       NC_021085.1            10345 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_021085.1 Cutibacterium acnes HL096PA1, complete sequence.
ACCESSION   NC_021085
VERSION     NC_021085.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 12:53:02
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1475701
            Orig. end    :: 1486046
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10345
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1480701:1481046](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5345
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10345
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10345
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             147..890
                     /locus_tag="ctg1_1375"
                     /transl_table=11
                     /translation="MSAAQRPPGLCPSAPLHVIRAAKREATQRLLGATMGLSDDEWQAP
                     SRLAGWTRAHIATHIARNAEAFEAVTKAVITNQKVPHLYPSDELRDRDIERGSERAGLQ
                     LQIDLDTTAGSLNTTFDALDDMEPGTAVWLTNDIRVDVTDLPALRLAEIALHHVDLDLG
                     MTVDDLPDVSARTLLEWVCFRLRDRPEVPAMRIVSDSGLTDRIGGVGFATTVHGPDGAL
                     AGWLSGRGGTERLAGADQLAVPMLI"
     PFAM_domain     216..626
                     /aSDomain="MDMPI_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11716.10"
                     /description="Mycothiol maleylpyruvate isomerase N-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1375_0013"
                     /evalue="5.80E-17"
                     /label="ctg1_1375"
                     /locus_tag="ctg1_1375"
                     /protein_end="160"
                     /protein_start="23"
                     /score="62.8"
                     /tool="antismash"
                     /translation="REATQRLLGATMGLSDDEWQAPSRLAGWTRAHIATHIARNAEAFE
                     AVTKAVITNQKVPHLYPSDELRDRDIERGSERAGLQLQIDLDTTAGSLNTTFDALDDME
                     PGTAVWLTNDIRVDVTDLPALRLAEIALHHVDL"
     aSDomain        216..833
                     /aSDomain="TIGR03083"
                     /aSTool="tigrfam"
                     /description="TIGR03083: uncharacterized Actinobacterial
                     protein TIGR03083"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1375_0003"
                     /evalue="8.30E-33"
                     /identifier="TIGR03083"
                     /label="ctg1_1375"
                     /locus_tag="ctg1_1375"
                     /protein_end="229"
                     /protein_start="23"
                     /score="112.4"
                     /tool="antismash"
                     /translation="REATQRLLGATMGLSDDEWQAPSRLAGWTRAHIATHIARNAEAFE
                     AVTKAVITNQKVPHLYPSDELRDRDIERGSERAGLQLQIDLDTTAGSLNTTFDALDDME
                     PGTAVWLTNDIRVDVTDLPALRLAEIALHHVDLDLGMTVDDLPDVSARTLLEWVCFRLR
                     DRPEVPAMRIVSDSGLTDRIGGVGFATTVHGPDGALAGWLSGR"
     CDS             936..1592
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170:metallo-beta-lactamase family protein (Score:
                     99.8; E-value: 2.5e-30)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1376"
                     /transl_table=11
                     /translation="MPLYHVDPGSEAALIKINDDVDLTKISVGTMDNNAYLIHPGAGPA
                     ILVDAAAEPGRLKALIGDDEVGAVITTHRHQDHTGALAEIVTMTGAQPWCGEPDAEAIE
                     ATTGVTCRTMWDGDLFRLGDVELDVIGLVGHTRGSIALRLHGNPSDHVLTGDSLFPGRL
                     GKTSGSREFESLYTDVCMKIFAPASDTTVIHPGHGDATTVGEERPNLPLWRARGW"
     PFAM_domain     1032..1439
                     /aSDomain="Lactamase_B"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00753.29"
                     /description="Metallo-beta-lactamase superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1376_0014"
                     /evalue="3.60E-11"
                     /label="ctg1_1376"
                     /locus_tag="ctg1_1376"
                     /protein_end="168"
                     /protein_start="32"
                     /score="43.5"
                     /tool="antismash"
                     /translation="NNAYLIHPGAGPAILVDAAAEPGRLKALIGDDEVGAVITTHRHQD
                     HTGALAEIVTMTGAQPWCGEPDAEAIEATTGVTCRTMWDGDLFRLGDVELDVIGLVGHT
                     RGSIALRLHGNPSDHVLTGDSLFPGRLGKTSG"
     CDS             complement(1601..2590)
                     /locus_tag="ctg1_1377"
                     /transl_table=11
                     /translation="LHVHAYVWIITILVMGALLFFDVLVLGRNPHIPSAKECATFVGVF
                     VGLAVLFGLGVWILQGHAAGGQFFAVWLTEYSLSIDNLFIFLILMEKFNVPRKLQQFAL
                     LVGIIVALVFRGVFIALGQAILEAWAWVFFIFGAFLLYSAIDQVREYRHRDDDDDEDPG
                     EDGRFMAWFRRTVPATGDYRGTKFFVRENGKTLATSMFMVCVALGATDLLFALDSIPAS
                     YGLTSEGYLILTANVFALMGLRQLYFLIGSLLERLVYLSLGLAVILGFIALKLIGHAMH
                     HYGLDQAWFGFSSEVSIGVSLGVIAVTLALTTVASLIKSRKDDATADV"
     aSDomain        complement(1625..2581)
                     /aSDomain="TIGR03718"
                     /aSTool="tigrfam"
                     /description="R_switched_Alx: integral membrane protein,
                     TerC family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1377_0004"
                     /evalue="1.20E-104"
                     /identifier="TIGR03718"
                     /label="ctg1_1377"
                     /locus_tag="ctg1_1377"
                     /protein_end="322"
                     /protein_start="3"
                     /score="347.9"
                     /tool="antismash"
                     /translation="HAYVWIITILVMGALLFFDVLVLGRNPHIPSAKECATFVGVFVGL
                     AVLFGLGVWILQGHAAGGQFFAVWLTEYSLSIDNLFIFLILMEKFNVPRKLQQFALLVG
                     IIVALVFRGVFIALGQAILEAWAWVFFIFGAFLLYSAIDQVREYRHRDDDDDEDPGEDG
                     RFMAWFRRTVPATGDYRGTKFFVRENGKTLATSMFMVCVALGATDLLFALDSIPASYGL
                     TSEGYLILTANVFALMGLRQLYFLIGSLLERLVYLSLGLAVILGFIALKLIGHAMHHYG
                     LDQAWFGFSSEVSIGVSLGVIAVTLALTTVASLIKSRK"
     PFAM_domain     complement(1763..2386)
                     /aSDomain="TerC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03741.18"
                     /description="Integral membrane protein TerC family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1377_0015"
                     /evalue="6.50E-46"
                     /label="ctg1_1377"
                     /locus_tag="ctg1_1377"
                     /protein_end="276"
                     /protein_start="68"
                     /score="156.4"
                     /tool="antismash"
                     /translation="FAVWLTEYSLSIDNLFIFLILMEKFNVPRKLQQFALLVGIIVALV
                     FRGVFIALGQAILEAWAWVFFIFGAFLLYSAIDQVREYRHRDDDDDEDPGEDGRFMAWF
                     RRTVPATGDYRGTKFFVRENGKTLATSMFMVCVALGATDLLFALDSIPASYGLTSEGYL
                     ILTANVFALMGLRQLYFLIGSLLERLVYLSLGLAVILGFIALKLI"
     CDS             complement(2784..4889)
                     /gene_functions="other (smcogs) SMCOG1122:ATP-dependent RNA
                     helicase (Score: 44.6; E-value: 1.3e-13)"
                     /gene_kind="other"
                     /locus_tag="ctg1_1378"
                     /transl_table=11
                     /translation="MRPVTDITRRVAPFHVVSEFQPSGDQPQAIAELEKRVNSGEQDVV
                     LLGATGTGKTATVAWLAERLQRPMLVMQPNKTLAAQFAQELRTFFPDNAVEYFVSYYDY
                     YQPEAYIPQTDTYIEKDSSLNKEVERLRHSATNSLLTRRDVIVVSTVSAIYGLGTPQEY
                     VDRMIPLEVGQEWDRDELLRDLVTNQYVRNDISGERGTFRVRGDTLEIFPVYEENALRV
                     EFFGDEIEALTTMHPLTGEIISEDEQVYVFPATHYVAGPERMERAIASIQQELEERLAV
                     LERDGKLLEAQRLRMRTTYDIEMMQQVGACAGIENYSRHIDGRAPGSAPNCLLDYFPED
                     FVLVIDESHVTVPQIGGMYEGDMSRKRTLVEHGFRLPSAMDNRPLKFDEFTQRIGQTVY
                     LSATPGSYETERAHGVVEQIIRPTGLVDPEIIVKPTRGQIDDLMGEIRTRVDRGDRVLV
                     TTLTKKMAEDLTDYLMEHGIRTRYLHSEIDTLKRIELLKELRMGEFDVLVGINLLREGL
                     DLPEVSLVAILDADKEGFLRSERSLIQTVGRAARNVNGQVIMYADQITDSMQVAIDETN
                     RRRDIQMAYNKEHGIDPQPLRKKIGDITEMLAREGADTDELVEKFNYGKGHRGYNSMIT
                     DEQRAAQGRRLDVSKMAEEDLGKLIVDLTTEMRSAAGELKFEVAARLRDEIADLKKELR
                     QMVEANR"
     PFAM_domain     complement(2814..2918)
                     /aSDomain="UVR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02151.21"
                     /description="UvrB/uvrC motif"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1378_0020"
                     /evalue="9.80E-06"
                     /label="ctg1_1378"
                     /locus_tag="ctg1_1378"
                     /protein_end="692"
                     /protein_start="657"
                     /score="25.2"
                     /tool="antismash"
                     /translation="KLIVDLTTEMRSAAGELKFEVAARLRDEIADLKKE"
     aSDomain        complement(2820..4850)
                     /aSDomain="TIGR00631"
                     /aSTool="tigrfam"
                     /description="uvrb: excinuclease ABC subunit B"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1378_0005"
                     /evalue="0.00E+00"
                     /identifier="TIGR00631"
                     /label="ctg1_1378"
                     /locus_tag="ctg1_1378"
                     /protein_end="690"
                     /protein_start="13"
                     /score="1063.9"
                     /tool="antismash"
                     /translation="FHVVSEFQPSGDQPQAIAELEKRVNSGEQDVVLLGATGTGKTATV
                     AWLAERLQRPMLVMQPNKTLAAQFAQELRTFFPDNAVEYFVSYYDYYQPEAYIPQTDTY
                     IEKDSSLNKEVERLRHSATNSLLTRRDVIVVSTVSAIYGLGTPQEYVDRMIPLEVGQEW
                     DRDELLRDLVTNQYVRNDISGERGTFRVRGDTLEIFPVYEENALRVEFFGDEIEALTTM
                     HPLTGEIISEDEQVYVFPATHYVAGPERMERAIASIQQELEERLAVLERDGKLLEAQRL
                     RMRTTYDIEMMQQVGACAGIENYSRHIDGRAPGSAPNCLLDYFPEDFVLVIDESHVTVP
                     QIGGMYEGDMSRKRTLVEHGFRLPSAMDNRPLKFDEFTQRIGQTVYLSATPGSYETERA
                     HGVVEQIIRPTGLVDPEIIVKPTRGQIDDLMGEIRTRVDRGDRVLVTTLTKKMAEDLTD
                     YLMEHGIRTRYLHSEIDTLKRIELLKELRMGEFDVLVGINLLREGLDLPEVSLVAILDA
                     DKEGFLRSERSLIQTVGRAARNVNGQVIMYADQITDSMQVAIDETNRRRDIQMAYNKEH
                     GIDPQPLRKKIGDITEMLAREGADTDELVEKFNYGKGHRGYNSMITDEQRAAQGRRLDV
                     SKMAEEDLGKLIVDLTTEMRSAAGELKFEVAARLRDEIADLK"
     PFAM_domain     complement(3090..3215)
                     /aSDomain="UvrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12344.10"
                     /description="Ultra-violet resistance protein B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1378_0019"
                     /evalue="3.60E-23"
                     /label="ctg1_1378"
                     /locus_tag="ctg1_1378"
                     /protein_end="600"
                     /protein_start="558"
                     /score="81.2"
                     /tool="antismash"
                     /translation="MYADQITDSMQVAIDETNRRRDIQMAYNKEHGIDPQPLRKKI"
     PFAM_domain     complement(3237..3554)
                     /aSDomain="Helicase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00271.33"
                     /description="Helicase conserved C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1378_0018"
                     /evalue="9.40E-17"
                     /label="ctg1_1378"
                     /locus_tag="ctg1_1378"
                     /protein_end="551"
                     /protein_start="445"
                     /score="61.5"
                     /tool="antismash"
                     /translation="IRTRVDRGDRVLVTTLTKKMAEDLTDYLMEHGIRTRYLHSEIDTL
                     KRIELLKELRMGEFDVLVGINLLREGLDLPEVSLVAILDADKEGFLRSERSLIQTVGRA
                     AR"
     PFAM_domain     complement(4119..4388)
                     /aSDomain="UvrB_inter"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17757.3"
                     /description="UvrB interaction domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1378_0017"
                     /evalue="3.40E-32"
                     /label="ctg1_1378"
                     /locus_tag="ctg1_1378"
                     /protein_end="257"
                     /protein_start="167"
                     /score="110.5"
                     /tool="antismash"
                     /translation="IPLEVGQEWDRDELLRDLVTNQYVRNDISGERGTFRVRGDTLEIF
                     PVYEENALRVEFFGDEIEALTTMHPLTGEIISEDEQVYVFPATHY"
     PFAM_domain     complement(4449..4832)
                     /aSDomain="ResIII"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04851.17"
                     /description="Type III restriction enzyme, res subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1378_0016"
                     /evalue="7.60E-09"
                     /label="ctg1_1378"
                     /locus_tag="ctg1_1378"
                     /protein_end="147"
                     /protein_start="19"
                     /score="35.9"
                     /tool="antismash"
                     /translation="FQPSGDQPQAIAELEKRVNSGEQDVVLLGATGTGKTATVAWLAER
                     LQRPMLVMQPNKTLAAQFAQELRTFFPDNAVEYFVSYYDYYQPEAYIPQTDTYIEKDSS
                     LNKEVERLRHSATNSLLTRRDVIV"
     CDS             5001..5345
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Lactococcin_972"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1379"
                     /sec_met_domain="Lactococcin_972 (E-value: 4e-12, bitscore:
                     43.7, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLSLLLAMKRFSRRSYKEEIVSTVWRHFAAVPITGLLLASTATI
                     AMADTVNPPEGGVWRYGRGYSDYFHGSKKHGSSVQGVNFVRSPCVKAGSWSYARTDAAR
                     FGNKAWYRTC"
     PFAM_domain     5163..5333
                     /aSDomain="Lactococcin_972"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09683.12"
                     /description="Bacteriocin (Lactococcin_972)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1379_0021"
                     /evalue="1.50E-15"
                     /label="ctg1_1379"
                     /locus_tag="ctg1_1379"
                     /protein_end="111"
                     /protein_start="54"
                     /score="57.5"
                     /tool="antismash"
                     /translation="EGGVWRYGRGYSDYFHGSKKHGSSVQGVNFVRSPCVKAGSWSYAR
                     TDAARFGNKAWY"
     CDS             5762..5980
                     /locus_tag="ctg1_1380"
                     /transl_table=11
                     /translation="MITHIAHMDQDQSTDRSGEYLVYGNAADATTFASGMSALGFRSSV
                     QGQVNLGLVASHNPDIIKAYGGMMGGH"
     CDS             5992..6930
                     /locus_tag="ctg1_1381"
                     /transl_table=11
                     /translation="MAAVFARTRRYGILRLHGHSWLHHASRETLHAVSVAAIGIGATAL
                     ISVPILGFYNGLAQWMRWFRWSVQIWILSVAVLLTVEIVTLAIAWSSAEILAQVKGRMT
                     SLPVFSASYLLRFPVAMLAILLIVSVTSATRELWRYEDQQAQWATVDRHVGRVALRGIG
                     SAVIDAASEKRMVDAVGAWLSDVDEHHRLIVANLSPVDVGLPAPIQLFIINDEYCQRHP
                     VPACASSPNVSTVTGTVPVSLSSVEPRIRHAIAQQLSAPAKAGKATIKWSRQEGSHDYF
                     TYGPQSPEQGLSATMTDPVMIRVPLRTIVRR"
     CDS             7476..7784
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 65.2; E-value:
                     1.3e-19)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_1382"
                     /transl_table=11
                     /translation="MTTMNGTATMNENSPVLRVENLSKTFGSRTLWKGHDFQASGGEII
                     ALRGPSGCGKSILLSTIGLLIRPDSGHIVIDGTDILTIPRRRHKRVRRETIGYLFQD"
     PFAM_domain     7578..7781
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1382_0022"
                     /evalue="1.40E-12"
                     /label="ctg1_1382"
                     /locus_tag="ctg1_1382"
                     /protein_end="102"
                     /protein_start="34"
                     /score="48.4"
                     /tool="antismash"
                     /translation="HDFQASGGEIIALRGPSGCGKSILLSTIGLLIRPDSGHIVIDGTD
                     ILTIPRRRHKRVRRETIGYLFQD"
     CDS             complement(8236..8484)
                     /locus_tag="ctg1_1383"
                     /transl_table=11
                     /translation="MKEQALIGARGLVSPSLCIPVLQSVSCYRGAAVMPFSRRLWRVLG
                     EVGLADEVGGMEAGLRTVVGSGGTRLSGGSGPAVNSG"
     CDS             complement(8720..8959)
                     /locus_tag="ctg1_1384"
                     /transl_table=11
                     /translation="VPQPTIVMASIAAIAALMRFQAVFCVCNCSTPVIMCAVSLFWLLG
                     PVEGVRVKGYRRKNSPHPDLFDGPVVDGMNDIPP"
     CDS             9321..9890
                     /gene_functions="transport (smcogs) SMCOG1033:iron compound
                     ABC transporter, periplasmic (Score: 63.7; E-value:
                     2.2e-19)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_1385"
                     /transl_table=11
                     /translation="VLNIKTRSLDEVLQTYQTLGKVLGHTKEAKKRSSQISAQVKSTVN
                     KMPADGKRVAILFATATSISLKLNNSIAGSMAKLLKLKNIASSAIPDDPNAETATLSVE
                     KITQQQPDIIMVTSMVQNNALARQIVNRELTSNPAWQAVDAVRKKKIIYLPQQYFLFNG
                     GPNYPDSVAYMAASVHPEIFGKPIEP"
     PFAM_domain     9348..9794
                     /aSDomain="Peripla_BP_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01497.20"
                     /description="Periplasmic binding protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1385_0023"
                     /evalue="1.70E-17"
                     /label="ctg1_1385"
                     /locus_tag="ctg1_1385"
                     /protein_end="158"
                     /protein_start="9"
                     /score="63.8"
                     /tool="antismash"
                     /translation="DEVLQTYQTLGKVLGHTKEAKKRSSQISAQVKSTVNKMPADGKRV
                     AILFATATSISLKLNNSIAGSMAKLLKLKNIASSAIPDDPNAETATLSVEKITQQQPDI
                     IMVTSMVQNNALARQIVNRELTSNPAWQAVDAVRKKKIIYLPQQY"
ORIGIN
        1 gtcatcgtag aggccgcgca agacagtccc gcagttctgc gcggctggca gaacggaaca
       61 cgatagcctt ttcacatcac tataaaattg gctccatcct ttcgttcatc tggcatgttc
      121 catcccgtgg cattaggttg gatgacatga gcgctgccca acgaccaccc ggtctgtgtc
      181 ccagcgctcc cttgcacgtg atccgggctg ccaaacgtga agccacgcaa cgtcttcttg
      241 gcgcaaccat gggactatcc gacgacgagt ggcaggcgcc gagtcgcctg gccggatgga
      301 cccgtgccca catcgccacc cacatagccc gtaacgccga agccttcgag gccgtcacga
      361 aagcggtcat taccaatcag aaagtccccc acctctaccc ctccgacgaa ctgcgcgacc
      421 gcgatatcga acgcggttcg gaacgcgccg ggctgcagct gcaaatcgac ctcgatacca
      481 ccgcaggctc cctcaacacc accttcgacg cgctcgacga catggaacct ggcactgcag
      541 tgtggctaac caacgacatc cgcgtcgatg tcactgatct gccagcacta cgactcgcag
      601 agatcgctct tcaccacgtc gacctcgatc tcgggatgac cgtcgatgac ctccccgacg
      661 tttccgcgcg tactctcctg gaatgggtct gcttccgcct gcgagaccgt cctgaggtgc
      721 ccgctatgcg tatcgtctct gattccggcc tgacggaccg cattggcggg gtcggattcg
      781 cgaccacggt ccatggacct gacggcgcac tggcaggatg gctatcgggc cgagggggaa
      841 ctgagcgtct cgccggagct gaccagctcg ccgtcccaat gctcatctga caggacagct
      901 ggcggattat ccgctcgtcc caggaaggaa tcgtcatgcc gctctaccac gtcgatccgg
      961 gctcagaagc cgccctcatc aagattaacg atgacgttga cctcaccaaa atctcggtag
     1021 gcaccatgga caataatgcc tacctcatcc atcccggagc ggggcccgcc atcctcgtgg
     1081 acgcagctgc cgaacccggt cgactcaaag ccctcatcgg tgacgatgaa gtcggagccg
     1141 ttattacgac ccatcgtcat caggaccata ccggggccct cgcggagatc gttactatga
     1201 cgggagccca gccgtggtgt ggagaacccg acgccgaggc tattgaggcc accacaggag
     1261 taacctgccg caccatgtgg gacggtgatc tgttccgtct cggagacgta gaactcgacg
     1321 tcattggact ggtaggccat acccgcggat ccatcgcctt acgtttgcac ggtaacccca
     1381 gcgatcacgt tctcactggc gattctctgt tcccgggtag gctcggcaaa actagcggaa
     1441 gccgagaatt cgaaagtctc tacaccgacg tctgcatgaa gatcttcgca cccgcgtcag
     1501 atacaacagt tatccatccc gggcatggcg acgccacaac cgtcggagag gaacgtccca
     1561 accttccact gtggcgtgcc cgcggctggt aaacgtcaga tcagacgtcg gctgtggcat
     1621 cgtctttacg acttttaatg agactcgcga cggtggtgag agccagggtc acggcgataa
     1681 cgcccagcga aaccccgatc gaaacctcac tgctaaagcc gaaccaggcc tggtccagtc
     1741 cgtagtggtg catcgcgtgg ccaatgagct tgagggcgat aaagcccaaa atcacggcca
     1801 gtcccagcga caagtacacc aaacgttcca acaggcttcc gataaggaaa tacaactggc
     1861 gcagacccat gagagcaaag acgttagcgg taaggatgag atacccctcg ctggtgagac
     1921 cataggacgc cggaatcgag tcgagggcga aaagcaagtc cgtggcgccc agggcgacac
     1981 aaaccatgaa catcgaggtt gcgagagttt taccgttctc gcgaacgaaa aacttcgtgc
     2041 cacggtagtc accagtagcc ggaaccgtgc gcctgaacca cgccatgaag cggccatcct
     2101 caccaggatc ctcatcgtcg tcatcgtcac ggtgccgata ctcacgcacc tggtcaattg
     2161 ccgaatacag caggaaagca ccaaagatga agaacaccca cgcccaggcc tcaagaatgg
     2221 cctgtcccag agcaataaaa acaccccgga aaacgagggc gacgatgata cctaccagca
     2281 gggcgaattg ctgcaatttc cgtgggacgt tgaacttttc catgaggatg aggaagataa
     2341 acaggttgtc gatcgacaag ctgtactcgg tcaaccacac tgcgaagaac tgtccccctg
     2401 cggcatggcc ctgtaggatc cagacgccta agccgaagag taccgccaag ccgacgaaga
     2461 cgccgacgaa ggtggcacac tccttggcgg aggggatatg ggggtttcgc cccaggacga
     2521 gaacgtcgaa gaagagcaga gcccccatca cgaggatggt gatgatccag acgtaagcat
     2581 gaacgtgcaa atcccggcct ccaaagggat agtccggagg tctcgtccgc gccggtacgc
     2641 cacatatcat cgcctgaccg gggctgtgta gccggaccgt gatggcacga tcgtgatgac
     2701 gaccacactt ttctcaggag tactcccctc caaggagttc catactcgca caccagggcc
     2761 tcgaccgcga ctcccgcccc tgtctaccgg ttggcctcca ccatctggcg caactctttc
     2821 ttaagatcgg cgatttcgtc acgtagccgg gcagcgactt caaacttgag ttcgccagcc
     2881 gcagaacgca tttcggtggt gaggtcgacg atgagcttgc ctagatcctc ttcggccatc
     2941 ttcgagacgt cgagtctcct gccttgggcg gctcgctgct cgtcagtgat catcgaattg
     3001 tagccgcggt ggcctttccc atagttgaac ttctcgacga gctcgtcagt atcggcacct
     3061 tcgcgagcca gcatctcagt gatgtcgccg atcttcttgc gcaacggctg tggatcgatc
     3121 ccgtgttcct tgttgtacgc catctggata tcgcgacgac gatttgtctc gtcgatggcg
     3181 acctgcatgg aatcagtgat ctggtcggcg tacatgatga cctgaccgtt gacgttacga
     3241 gcagcgcggc cgacggtctg gataagggac cgttcagaac gcaaaaagcc ttccttgtcg
     3301 gcgtcgagga tcgccaccaa ggaaacctcc gggaggtcaa gtccctctcg tagcaggttg
     3361 ataccgacaa gcacatcgaa ctcgcccatg cgcaactcct tgagcagctc gatgcgtttg
     3421 agtgtgtcga tctccgagtg caggtaacgg gtgcgaatcc cgtgctccat gaggtagtcg
     3481 gtgaggtctt cggccatctt cttcgtcaga gtcgtcacca agacacggtc gccacggtcc
     3541 actcgggtac gaatttcacc cataaggtcg tcaatctggc cacgcgtagg cttgacgata
     3601 atctccggat ccaccagacc tgtcggacga atgatttgtt cgacgacgcc gtgagctcgt
     3661 tcggtctcgt acgaaccggg cgtggcggac aggtagacag tctggccgat ccgctgggtg
     3721 aactcgtcga atttgagagg acggttgtcc atcgcgctgg gcagtcggaa accatgttct
     3781 accaatgtcc gcttgcggct catgtccccc tcatacatcc cgccaatctg cgggacggtc
     3841 acgtgggatt catcaatgac gagcacaaaa tcttccggaa agtagtcaag cagacagttc
     3901 ggggctgagc cgggagcgcg tccgtcgatg tgccgcgaat agttttcgat gccagcacag
     3961 gcaccgacct gctgcatcat ctcgatatcg taggtagtac gcatacgtaa ccgttgggcc
     4021 tccaacagtt tcccatcacg ctctagaacg gccaggcgct cctcgagctc ctgctggatg
     4081 gacgctatgg cccgctccat acgttccggg ccggcgacat agtgggtagc cgggaacacg
     4141 tagacctgct cgtcctcgct gatgatctcc ccggtgagtg ggtgcatcgt cgtgagggcc
     4201 tcaatttcgt cgccgaaaaa ctcgacacgc agcgcattct cctcataaac cgggaaaatc
     4261 tcgagggtgt ccccgcgcac ccggaaggtg ccgcgctccc ccgatatgtc gttacggacg
     4321 tactggttgg tgacgaggtc gcgcagcaac tcatcgcgat cccactcctg gccgacctcc
     4381 agtggaatca tccggtctac gtattcctgt ggcgtgccca ggccatagat agctgaaacg
     4441 gttgacacca cgatgacgtc gcgacgggtg agcagggagt tcgtcgcgga gtggcgcaac
     4501 ctttcaactt ccttgttgag gctggaatct ttctcgatgt aggtatccgt ctgtgggatg
     4561 tacgcctcag gttggtagta atcgtagtaa gagacgaagt actcgacggc attgtcaggg
     4621 aagaaggtac gtagttcctg ggcaaactgg gcggccaacg tcttgttggg ctgcatgacg
     4681 agcatcgggc gctgcagcct ctccgccagc cacgccaccg tggccgtctt gccagtaccg
     4741 gtggcgccga gcagaacaac gtcctgttca ccactgttaa ccctcttctc caactccgca
     4801 atggcctgcg gctggtcacc agaaggctga aactcactga cgacgtgaaa aggggctacg
     4861 cggcgagtga tgtcagtgac agggcgcata gctccaccct agttcaagcc acccgcgata
     4921 ggattagcta aaagcatgcg accgggttcg ggacgtcaga tctgaaagcc tgcatctccg
     4981 gtcccgatga gcctcgctgg atgaccctct ccctcctgct ggcaatgaag cgtttcagta
     5041 ggagaagtta taaggaggaa atcgtgtcca ccgtttggcg tcacttcgca gcagtcccta
     5101 tcacgggcct gctactcgct agtacagcca ctattgctat ggccgacacc gtcaacccgc
     5161 ccgagggcgg agtttggcga tacggacgtg gatactcgga ctattttcac ggctcgaaga
     5221 aacatggcag ttcagttcaa ggggtcaact ttgtgcgctc gccatgcgtc aaggccggca
     5281 gttggtccta tgctcgcacc gatgcagcac ggttcgggaa caaggcttgg tatcgcacct
     5341 gctgacaacc ccatcacagg cggcacgccc tacggtggga cgtgccgcct gatacccctc
     5401 cacggtccga tcagaaggaa gccgccacaa tgatgagacc ggccctcacc ggtatccctc
     5461 ccctactttc tgacggcagt tgtcgccgtt cttatggcat cattcctgtt gggcgcggca
     5521 gaaacggtgc tcccctcagc tgggcacccc gtcatcgttc tcgtcgaggg aacaccagac
     5581 cgaaacgtct cggcggtcga ctcgtggatg tccacgtatt cgcaacgaca acatgtggcg
     5641 gtcgggcgtt ggcaggccga tttgaacaat ccggagtcct ctcgggggct ctatttggtt
     5701 tccgcagccg gcggcactct caatcccttt cctaaagggt tacccgaatc tgtcatcgca
     5761 aatgatcacc catatcgccc acatggatca agatcagtcc accgatcgca gcggcgagta
     5821 cctcgtctac ggcaacgccg ccgatgccac cacattcgcc tccggaatga gtgcattggg
     5881 gtttcgctcc tcggtacaag gccaggtgaa cctgggactc gttgccagcc ataatcctga
     5941 catcatcaag gcgtacggcg ggatgatggg ggggcattag tcgccctggt catggcggcg
     6001 gtgttcgccc ggactcggcg ttacggtatt ctccgtttgc acggtcactc gtggctgcat
     6061 catgccagcc gagaaactct tcatgcggtg tccgtcgcag ccataggcat aggagcaacg
     6121 gctttgatca gtgtgccgat cctcggcttt tacaacggtt tagctcaatg gatgcgatgg
     6181 tttcgctggt cagtccagat atggatacta tccgtcgcag tactcctcac agtcgagatc
     6241 gtgacgttgg ccatcgcatg gtcaagcgca gaaatcctgg ctcaggtcaa gggtcgaatg
     6301 accagtctcc cggtcttctc cgcctcgtat ctgcttcgct ttccggtggc catgttggcg
     6361 atactgctga tagtttcagt cacctctgcc acacgggaac tgtggcgcta tgaagaccaa
     6421 caagcccaat gggccacggt cgatcgtcac gtggggcggg tcgcgctccg tggcatcggc
     6481 tcggctgtca tcgacgccgc cagcgagaag cgtatggttg acgcagtcgg cgcatggctg
     6541 agcgacgtgg acgaacacca ccgtctcatc gtcgcaaacc tcagtccggt tgacgttggt
     6601 cttcctgcac cgattcagtt gttcatcatc aatgacgaat actgccaacg tcatccggta
     6661 ccggcatgcg cttcctcccc aaatgtatcc accgtcacgg gaaccgtacc tgtatcactg
     6721 tcctcagtgg aaccccgcat ccgccatgct attgcccaac aactctccgc accagcaaag
     6781 gccggcaagg caacaatcaa gtggtcgcgg caagagggct ctcacgacta tttcacctac
     6841 ggaccgcagt cccccgaaca gggtctgtcg gcaacgatga ccgatcccgt gatgatccgc
     6901 gtccccctca ggactattgt caggcgatga cctcacgaca gcgttgacta ccggtggaat
     6961 tctcctactc gatcccaatt ccgagtcccg acgtgtcacg tccagtccct cgcttgccag
     7021 ggcagttgcc agcatctcac ctgcaggggc atccacagcc cagaaagctt cccaacaacg
     7081 ccaacagttg ctgatcgcga gcctcggcgc gctcgccagc ttactcactg tcgtggcaac
     7141 gtcggtgagc atcaccggaa tgtacagcac tgtgcaccgg caacgaagct tggtgcgcaa
     7201 actccatggg tggtcggggc tctacatgtt ccgacaagtt gtcgcatggg aaaccggttt
     7261 gtggggcacc ctggccatag ttattgcatg gcgatcggtg acctcatggc aggctggacg
     7321 aaccgaatcc atcgcggagg gaaggcgacc ccatgacctg ctgtcctggg cttacaccgc
     7381 accgtgggct tgggcaggca cggcaggcgt gggaatcgcg actctgagca ttctctccta
     7441 tgcaggttct atcgaacatt gaggacgcgc gaagcatgac gacaatgaat gggacggcaa
     7501 ccatgaacga gaatagcccc gtgttacggg tggagaacct ctccaagacc ttcggttcca
     7561 gaaccctctg gaagggccat gacttccagg catccggcgg cgagataatc gccctacgtg
     7621 gccctagcgg ttgcggaaaa tcgatcctat tgtcgacaat cggtctcctc attcggcccg
     7681 acagcggcca catcgtgatc gacggcacgg acatccttac catcccgcgt cgacggcaca
     7741 aacgcgtccg ccgtgagacc atcggctacc tctttcagga ttaggctctg ctcgagagcg
     7801 ctacggtacg cgaaaaccta gacatcgcgg cgcgcccaag acccttacta cccaagccct
     7861 ccttcgcatc cgccttggaa cgcgttggac tgcccgggca ggaacaaact cccgtacaca
     7921 cccttagcgg aggcgaacag cagcgtgtcg ccttggctcg attgctcctc aagccgagcc
     7981 ggatcatcct gaccgacgaa cccacggcgt cacttgaccg ggacaacgag gacctggtcc
     8041 taaatcttct acaagatctc gccaatgaag gcaaagtgat acttctcgcc actcacagcg
     8101 gccgagtcgc gagtcgttgt tcgcgggtgc tgtcactgca ccaccattaa ctgcccaacc
     8161 gcctcacgcc aagggacagg aagactcgct ctcagtatcc tcgaccacgt gcgaccgact
     8221 ccggtgggca ggttcctagc cactgttaac cgctgggcct gaccccccgg aaagcctcgt
     8281 accacccgac ccaacaacgg tacgcaatcc agcctccata ccacccacct catcagctaa
     8341 accaacctca ccaagaacac gccacaaccg acgcgagaaa ggcatcaccg ccgcccccct
     8401 gtagcagctg accgactgca gcacgggtat gcataggctg ggcgaaacca aacctctcgc
     8461 cccgatcaga gcctgctctt tcatgctgca gttccgggaa gtacaacgtc atgaccgcca
     8521 acaactagag gtcaacataa gttttcttcc cgcaacctaa caccaaatcc atcccgtgcg
     8581 atcagtcact ccaccacaag cccgcaacta tcattacagc acgtttatgc aactcacaga
     8641 cattgaggat aggacacata cccacccaac agaagcgcca ccggacatcc taaacaccca
     8701 cccccaataa acaggcaaat tagggaggga tatcattcat cccatcgaca actggaccgt
     8761 cgaacaagtc cggatgtgga gagttctttc tacggtagcc cttcaccctg acaccctcta
     8821 ccggccctag aagccagaag agagaaaccg cacacataat aacaggagtt gaacagttgc
     8881 acacacagaa aacagcctgg aagcgcatta gtgcagctat agctgcaata ctggccatga
     8941 caatggtcgg ctgcggcact tcagatcctt caaagggagg agaatccaga gcagaagaag
     9001 caaagacgtc cttcagtgta accgacagct tcggccataa agtcgatttt aagacaagac
     9061 cacagcgagt atgcctgttg tctgcgacac tactcagcat ttggtatgac ttgggcggca
     9121 cggcggcatg cacgccatcc ttaactggaa atgaaaaact tcaaccagcc catgctgcag
     9181 ccataaagaa ggtcaccaag gtcggcatga tatatgctgt caatttagaa cgaatacttg
     9241 ctacaaaccc agacctcgtc atcgcacctg gagccgtaag ccagaacgta acagacaaac
     9301 tttcttctca aggaattcct gtgttgaaca tcaaaacgag gtcactggat gaggttctcc
     9361 aaacttatca aaccctcggt aaagtactcg gccacaccaa agaagccaaa aagcgttcct
     9421 ctcaaatttc cgcacaggtc aagtccaccg ttaacaagat gccagcagac ggcaaacggg
     9481 tcgctattct gttcgcaaca gccacgtcaa tatcactaaa gttaaacaac agcatcgccg
     9541 gatcaatggc caaacttctc aagttgaaga acatcgcttc gtcggcaatt ccagatgacc
     9601 caaatgccga aactgccacg ctcagtgtcg agaaaataac tcagcaacag cccgatatca
     9661 tcatggtcac ctcaatggta cagaacaacg cactagcccg gcaaatagtg aacagagaat
     9721 tgaccagcaa cccagcctgg caggcagtgg atgccgtacg aaaaaagaaa atcatttacc
     9781 tgcctcaaca atatttcctg ttcaacggtg gccccaacta cccagattcc gtggcttaca
     9841 tggcagcttc tgtgcatccg gaaatctttg gaaaacccat tgaaccatga caatacccgc
     9901 caaaacaaaa acactcacat cgacaacgga gacaacgtca agtaacagcc accgaaggca
     9961 ccacctcacg gcaatcgtat tcgtcatcct tgttgcgatc atgatcgtca gcgtcataac
    10021 agggatcggg ttcggttcga tacagttgtc accctctgac gtagtcaaag gattgttcgg
    10081 tccgtccgat ttccaatggc atagggtggt atggggagtg agattcccca gggtcgtcct
    10141 tgctgccctg gtcggcatga accttgcaac gtcgggtgtg attcttcaag ccgtgatgag
    10201 caatcccctt gccgatccga gcatcatcgg ggtctcctcg ggcgcagggc ttctaggaat
    10261 aggcacgctg cttattttcc cagaacgagc aaaccttgta cctgtaatgg cgttcatcgg
    10321 tgcgatgttg gcagccatgg caatc
//
