LOCUS       NZ_CP019962.1          24463 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP019962.1 Eubacterium limosum strain ATCC 8486 chromosome,
            complete genome.
ACCESSION   NZ_CP019962
VERSION     NZ_CP019962.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:37:01
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1848878
            Orig. end    :: 1873341
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24463
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1858878:1863341]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14463
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..24463
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..24463
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="4"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             450..1781
                     /locus_tag="ctg1_1693"
                     /transl_table=11
                     /translation="MADRQPRKGWYKLDNAGTLYSSIASSRVSTVFRMTLGLTEEVDPE
                     ALQKALDNVMVRFPYFNVTLRRGFFWYYYDHSENRPLVEKESHYPCKTIRQRKGVFPFR
                     ILYYGRYIHLEMSHSICDGYGGLAFLKPLVLEYFKVKDGIVCKELGDIIDINSPVDPEE
                     YEDAFKKYYEKRVPPPEKGEKAYHFPFGLLDKGQYLLLTGIVPVKEVLVQSRAHKCTLT
                     QFITALYFESIQEYILGLEKKKRARSGHTKANIAINVPVDLRAFFPSKTLRNFFISLNP
                     AIDMQLGVYSLEEIIDQIKGYMGLYINQKNINRYVSRNVRNEELMVLRMIPLWVKRVIM
                     PIVYKRYGERSYTSSVSNLGSIWMPEEVRDRITGFEIFPPPSAGNKLKIVMASYGDKLY
                     ISFGKTTGEKDIERIFFRKLRKLGIPVRIEGNQINYYEVEKEDA"
     CDS             1781..2497
                     /locus_tag="ctg1_1694"
                     /transl_table=11
                     /translation="MAYCPKCGVEVDNNVKNCPLCDFPIPDIGEEPKGEKRYPLAVNTY
                     PQEHQEKKNRIFYALEIIVAAVFLINMVLYWFIPFNPTITQIIMISSVSLALYLMFCFN
                     YLPALVNLLGCYFTTLLLGSIIYVIVGGSGDWFVNYAMPIVTILFIDILIFGIIYKKNR
                     HRNQFIYAPVFLIAFSATLCLGIDGVISYNILGHLRFTWSLIVAISGICIIALLMGIYH
                     GVPDRTKAYLKKKLHV"
     CDS             2510..3049
                     /locus_tag="ctg1_1695"
                     /transl_table=11
                     /translation="VKRQEKIEARLLEMPLYDYAFFPVKDIIFTQDVRTICAMNDCGMY
                     GRRWVCPPVIGSIEDCIAECQAYEHAFLFSTVTEVADSFDLKACVEARGDHEAITYEVA
                     QIFRQETENPLILSTGCIPCEHCAYPDAPCRHPERAFKTIESHGIMIMQMAAQQGLNYD
                     CGQNIVTYFSLVLYNL"
     PFAM_domain     2570..3040
                     /aSDomain="DUF2284"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10050.11"
                     /description="Predicted metal-binding protein (DUF2284)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1695_0064"
                     /evalue="6.40E-41"
                     /label="ctg1_1695"
                     /locus_tag="ctg1_1695"
                     /protein_end="177"
                     /protein_start="20"
                     /score="139.9"
                     /tool="antismash"
                     /translation="FFPVKDIIFTQDVRTICAMNDCGMYGRRWVCPPVIGSIEDCIAEC
                     QAYEHAFLFSTVTEVADSFDLKACVEARGDHEAITYEVAQIFRQETENPLILSTGCIPC
                     EHCAYPDAPCRHPERAFKTIESHGIMIMQMAAQQGLNYDCGQNIVTYFSLVLY"
     CDS             3127..3660
                     /locus_tag="ctg1_1696"
                     /transl_table=11
                     /translation="MQPQEKAVYQDILQCIFARYLEDYSENTYSELLKKYTGLSVIETG
                     EAREASYEMVLQLLKRRTRRYTGLGRMAEGDAREENILYPAAFETQGADPELARETDYG
                     TAWDGFDNMLLELPEEKEVECKMALNSLESIIHDPSMTKPQKELLSSILLDWIAHEPED
                     IGILFVPILLQIYE"
     CDS             3920..4291
                     /locus_tag="ctg1_1697"
                     /transl_table=11
                     /translation="MKADLVRIALIPYFVLLLVICNWNVKLYSAVTLNSFYFLEYILFI
                     FCGLAIARLMDVSQSTYRQKSARIIIIVNLVVLLGFFLLGFLRIFVFFDVRYFYQISFL
                     LFGYYVYLLVISLRKGENP"
     CDS             4288..4551
                     /locus_tag="ctg1_1698"
                     /transl_table=11
                     /translation="MKKYVRNGMIICALSPLIAYYLHFMVGTVSSRIFMPLSYISNNPA
                     IAYLGYNGGVEMVPAWTIAVNVTVLIYLAYRRETDKKKGEEP"
     CDS             4633..4878
                     /locus_tag="ctg1_1699"
                     /transl_table=11
                     /translation="MQYQKLSYPAKNYASELFEEYRNRLKENIPDEKASVINFKPDMNS
                     TRYICELQKFFHFQVKENQVIINRFFVDQMTCFYKW"
     CDS             4916..5317
                     /locus_tag="ctg1_1700"
                     /transl_table=11
                     /translation="MKNKICLVYLAVVPYLILAMVTVHWYEYYRPSPSTLAFEPFLFVF
                     KILMYPVIGVLLALLHIIPKSVYGTKWARSIMAVNFMVPIAFWAIYYSDFGGLGVRMLF
                     FIKVPVFTTLSFLLIGYYLVLLMMSFKKG"
     CDS             5322..5498
                     /locus_tag="ctg1_1701"
                     /transl_table=11
                     /translation="MKGKVILIIFSLAVLTGLYYVVGDDLWRSLTASFFFTAISVSVCV
                     QFIELIKKYEIKR"
     CDS             5509..6012
                     /locus_tag="ctg1_1702"
                     /transl_table=11
                     /translation="VKKKLLTVLALLAVCCLMFLGCSEKEKASEEIPLSERSIEEQVQN
                     GRSDIFKEYDNIKAFRAVYQNDLRTMNGLVDPHKYDIVLKNLEYEYPQIQESSKVTATY
                     KKIDKDKYVLKYYDSFEEYGELKESDLAALNESGKAQGITYKSKMAELVPEQENIRAYY
                     EKVV"
     CDS             6048..6320
                     /locus_tag="ctg1_1703"
                     /transl_table=11
                     /translation="MRDTVKNSVSCVVYSVIIVVDIVLNYQLFHWLSKPLYRINERLFG
                     PTELGLKGQPPFVVFFQFFIPVILFFVIVMAGYFLCKKIEEKKNR"
     CDS             6376..6897
                     /locus_tag="ctg1_1704"
                     /transl_table=11
                     /translation="MKVKAYLNRLLREESSSMWGVRLIIKIILVLLVLTVYALLNTLVL
                     ESISDRAYALINPELENNMVLYHYVFSPAVILALVLSMVWISKDFKLKRRSKVKKDSIV
                     IGLILFALYMILYLPYIFYSFQSSAFFVRMVLFFLSKGANRAFLQVLLLLSGYFIINGV
                     VRAPVVGDKN"
     CDS             7181..7684
                     /locus_tag="ctg1_1705"
                     /transl_table=11
                     /translation="MKKKLFVMMLALLVFSLPLSGCTPDKEDVQKENKAEKTMEEQVEN
                     NQNAIFKQYDNIKAFRSEYQKDLETMNALVDPNKAEIVLSDISYTAGAPSSDSKVDATY
                     RRINKETYVLKYYESWDVYNEQVKNDLSALNESVKDQGIEYRIDRAELVPEDNRVRAYF
                     EKVT"
     CDS             7844..8572
                     /locus_tag="ctg1_1706"
                     /transl_table=11
                     /translation="MFRIGVCDDEAYFRQVLEKQLMTYLKFYEQKAEVCLFENGSDFLK
                     AAGDQAFNLVFLDIEMEAEETGIKVAESLQKESPDTLVIFVTSHSEYVPRSFRVNAFQY
                     LTKPVKTELITEEIERAMRYIKTQRSRYEINWNGKQYFILIKKIRYVETDKGHNVVVHT
                     IEENYKTKRSLNDVEDDLKPYGFLRIHRSVLINMNFICGKRDKEICIQKKPEEIWLSVS
                     RDRQKTVDAAYISWRRKSSI"
     PFAM_domain     7859..8197
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1706_0065"
                     /evalue="4.10E-18"
                     /label="ctg1_1706"
                     /locus_tag="ctg1_1706"
                     /protein_end="118"
                     /protein_start="5"
                     /score="65.7"
                     /tool="antismash"
                     /translation="VCDDEAYFRQVLEKQLMTYLKFYEQKAEVCLFENGSDFLKAAGDQ
                     AFNLVFLDIEMEAEETGIKVAESLQKESPDTLVIFVTSHSEYVPRSFRVNAFQYLTKPV
                     KTELITEEI"
     PFAM_domain     8258..8530
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1706_0066"
                     /evalue="2.80E-15"
                     /label="ctg1_1706"
                     /locus_tag="ctg1_1706"
                     /protein_end="229"
                     /protein_start="138"
                     /score="56.4"
                     /tool="antismash"
                     /translation="KQYFILIKKIRYVETDKGHNVVVHTIEENYKTKRSLNDVEDDLKP
                     YGFLRIHRSVLINMNFICGKRDKEICIQKKPEEIWLSVSRDRQKTV"
     CDS             8575..9867
                     /locus_tag="ctg1_1707"
                     /transl_table=11
                     /translation="MILKLICESMIAGFEVVLIYFWAKAFSDEKAERWQVVVAASVIFI
                     LILSVSMISFQPFVLITNATICTFIMLWVMNRRIKINFWLTLCFSTLMFLSETIGGMLY
                     AFIGNVDFNATRFDPLYRLRANIISELVAFTIIRIISVRQRHSFYFPPLRIILQIVVLP
                     LTSILAVVEMGLGQAGAYEIGGIVFNLAIIAGLAMANIFAFYLFEREQLYTEQKQKEAL
                     YRQQLEYQKESYRNLTTSQNEVRKIRHDLKNTLTAVSGYLKAGVTEKAEDLLEAMVTDL
                     KKTEQAVYTGYPAVDAVVFAKASRMERDKIPFSKTLILPETLPISEEDLFILLGSALDN
                     AIEACEKIEREGRYVLLKTGFDERRFWIWIENAAKLTEEEQAGRLSTRKADKKSHGLGL
                     LTIQKIVEKYNGMWQIKPEKLKFTLNIEFFL"
     PFAM_domain     9271..9435
                     /aSDomain="SPOB_a"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14689.8"
                     /description="Sensor_kinase_SpoOB-type, alpha-helical
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1707_0067"
                     /evalue="4.20E-07"
                     /label="ctg1_1707"
                     /locus_tag="ctg1_1707"
                     /protein_end="287"
                     /protein_start="232"
                     /score="29.6"
                     /tool="antismash"
                     /translation="SYRNLTTSQNEVRKIRHDLKNTLTAVSGYLKAGVTEKAEDLLEAM
                     VTDLKKTEQA"
     PFAM_domain     9547..9852
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1707_0068"
                     /evalue="1.00E-21"
                     /label="ctg1_1707"
                     /locus_tag="ctg1_1707"
                     /protein_end="426"
                     /protein_start="324"
                     /score="76.8"
                     /tool="antismash"
                     /translation="ISEEDLFILLGSALDNAIEACEKIEREGRYVLLKTGFDERRFWIW
                     IENAAKLTEEEQAGRLSTRKADKKSHGLGLLTIQKIVEKYNGMWQIKPEKLKFTLNI"
     CDS             10001..10162
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1708"
                     /sec_met_domain="TIGR04223 (E-value: 2.2e-12, bitscore:
                     44.7, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKLMEYAFKYGSMISALALMIGVSAGGAACWGWQYQPKEPEGM
                     RKFKRNLD"
     aSDomain        10037..10141
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1708_0021"
                     /evalue="2.30E-12"
                     /identifier="TIGR04223"
                     /label="ctg1_1708"
                     /locus_tag="ctg1_1708"
                     /protein_end="47"
                     /protein_start="12"
                     /score="44.7"
                     /tool="antismash"
                     /translation="GSMISALALMIGVSAGGAACWGWQYQPKEPEGMRK"
     CDS             10229..10702
                     /locus_tag="ctg1_1709"
                     /transl_table=11
                     /translation="MFLHRIQIKKEKEMKKVLSKASLGIVVMLLMLSFAGSAFAASEAD
                     EQIIQPRSENVFFSFPVSGTSGRCTGEALKHSTYTPYWVQFNWSSASNNIILNTVMHNS
                     DHASRGQGKVLEGTSASIASTGTAYYYYHGNLWREFEWDPAVSVSGYFSPDNY"
     CDS             10774..10920
                     /locus_tag="ctg1_1710"
                     /transl_table=11
                     /translation="MKKIFILFISIMVLLSVTACSITGKIDEPKWPDETTKEYIEKVEN
                     ELN"
     CDS             10936..11760
                     /locus_tag="ctg1_1711"
                     /transl_table=11
                     /translation="MEITKYRWFHKYRIIVLSIFFLGLWISWYLLGNIYGVTLGFDMAA
                     PDLGENVQAIKQNLLGQLLTIDHFVSSTFRFSMILGPVLICANTLLFIWEKKGYLAFKL
                     PRKNNYKGVIINTILIHAFINGTTFYFVYILFLSLGMLFNAAHMEIARTSFDFLFGRNF
                     SIESPYFYYVLDGFIKFFVFGFVYSLFSNTIALVSSKSYVSVIIPIIYYFGFSVIFATG
                     LQYMPLAPVYTQGFTSFVDMPLWMAFTPMIIPVVTSFFIIIWFLKRKEKYVD"
     CDS             11750..12373
                     /locus_tag="ctg1_1712"
                     /transl_table=11
                     /translation="MWIKIFAVIILWMFYIYYDPMGPFGGLFGDMGSGMLVTYLCYFFI
                     AMHLSFNRINSFILSRFVFKKDFYFWALKKILKVSSLYVLICTFTYVFINYILRHNDMV
                     TIYIIVKFMTGSIINISLLNFIILLIKLQYNTIFSMIFAGCIITLAYITGGVQLIRYNI
                     SFIASAYTDINGYMRPMFTIMGYLIILSIMLILLSRNKKMDISI"
     CDS             12376..13056
                     /locus_tag="ctg1_1713"
                     /transl_table=11
                     /translation="MKIKSISFFCATLLTLEINIWRNVQDNKKIEDIIKIIFLSDNDET
                     GISITSLITCFAFVIFSVLFVINIKNDISKNYRSMILQRYRSRRSFLMQHQKKGIQNSL
                     ILTISIFVCLVLFYSILEFKLINLESLPGDQLMSLFINIFLFLNISITFNTIIVLKKSN
                     IQGITANILLIVIVILLDISIKEISILTFGSIILLVRGTVFLSNIIFVLIIYLYFFIKN
                     IDIL"
     CDS             13068..13712
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 146.7; E-value:
                     1.5e-44)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_1714"
                     /transl_table=11
                     /translation="MQSIIQIEKASKTFKDKSVFKDVNISIQKGSCIGFSGYNGCGKSV
                     LLKCICGFSLLNQGRIICNNKTINKDIDFIQDTGIIIETPEFINDLTGYKNLKIIAEIR
                     NVIDDKDILKTMEILDLEKDKDKKVGKYSLGMKQKLRIAQAIMEKPKILILDEPTNGLD
                     KRSVVIVREILKKFIKKGGTLVMTSHNKEDMDILCDQVYEYDNYNFYMKSK"
     PFAM_domain     13128..13547
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1714_0069"
                     /evalue="2.60E-27"
                     /label="ctg1_1714"
                     /locus_tag="ctg1_1714"
                     /protein_end="160"
                     /protein_start="20"
                     /score="96.1"
                     /tool="antismash"
                     /translation="KDVNISIQKGSCIGFSGYNGCGKSVLLKCICGFSLLNQGRIICNN
                     KTINKDIDFIQDTGIIIETPEFINDLTGYKNLKIIAEIRNVIDDKDILKTMEILDLEKD
                     KDKKVGKYSLGMKQKLRIAQAIMEKPKILILDEPTN"
     CDS             13879..14463
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1715"
                     /sec_met_domain="AgrB (E-value: 3.5e-34, bitscore: 115.7,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHNLSQKLTSTFIHHRIIDAEDREVYIYSFELLLSAVVNLAVVV
                     LLICLTGQVWGGVGFVLAFLVLRQSAGGYHASSHFFCILSFTVIFLVFLAVIIFLPPLY
                     YLPVILGALIIGIPVIVLTAPVAHENKPLTGAERARLSRLAKLTVVVLTALIMTGWYLA
                     PWNAAPAGAALGLLTVALSSLAALYQKRKRD"
     PFAM_domain     13894..14358
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1715_0070"
                     /evalue="1.40E-33"
                     /label="ctg1_1715"
                     /locus_tag="ctg1_1715"
                     /protein_end="160"
                     /protein_start="5"
                     /score="115.9"
                     /tool="antismash"
                     /translation="SQKLTSTFIHHRIIDAEDREVYIYSFELLLSAVVNLAVVVLLICL
                     TGQVWGGVGFVLAFLVLRQSAGGYHASSHFFCILSFTVIFLVFLAVIIFLPPLYYLPVI
                     LGALIIGIPVIVLTAPVAHENKPLTGAERARLSRLAKLTVVVLTALIMTGW"
     CDS             14572..14916
                     /locus_tag="ctg1_1716"
                     /transl_table=11
                     /translation="MNKKDLYAVLKDKTRIAWVEVFTDPEAGDGLRVWFEDWRGLEFYR
                     SKATFIKWLEEWDIVSTAAAEKAARALLPGSQLLPMYRGPKCTFVQIKTKSTKAGEKYA
                     YSWVNLDLIN"
     CDS             15242..15730
                     /locus_tag="ctg1_1717"
                     /transl_table=11
                     /translation="MNNKINRMVVTPEELKDQPVISTLDQLFCMELMDLQMNREELLRA
                     YYNRTLFLGKSPEQPVTVVYGTGATPYYNIREAAALMGKREGIDAFIAEHGDALGVTMR
                     IAAAPDRLGLLEFLPTADIEGIHRLAALLGKEADSEGVAIMFELLEEKAVAWGRQCYA"
     CDS             15723..16253
                     /locus_tag="ctg1_1718"
                     /transl_table=11
                     /translation="MHKFTITDTTCYDALWLPGLETIPAVIDPPMYYGGEPEIWLALSP
                     ILPLLGQTSASKLAGLIAPGSKCKRRVYFGGRHRHMWMVNMQGLRGLLLFIKDDVKMEW
                     AKEQFERKVHALEMLHKGDAKTSILYHYEEGSEPVPAEEYGCEAGTLARVLIDQHRRCQ
                     KLEEMLEQVENGA"
     CDS             16243..16725
                     /locus_tag="ctg1_1719"
                     /transl_table=11
                     /translation="MGLNYLAELNAMRDYLLLRPLASGQISLWHGLMMINNLCGWKSWF
                     TAPNMTLQAFSGLSDSGIHKARKVLKERELIDYLPGSSGVIPAKYHIYPVSLRVREARG
                     SKDSSTGSSTSRSTGGGAGSGTGGSTAFYKQNKPDKKRQKETTNPFLKMLSDEEEM"
     CDS             16722..17294
                     /locus_tag="ctg1_1720"
                     /transl_table=11
                     /translation="VNRNETLKIMAVIKAAYPYYYNNQSEEDLKTVVNLWQGMFEEYEY
                     RLVSGAVRAFIASDTKGFPPSVGMVLDKLRLLTAPRELSEMEAWNQLSRAVKNSAWYAE
                     EEFDKLPEDIRGIVGSPASLREWALMEAGTFHSVIQSNFMRSYRACRGRKRALEELPES
                     VRGMIGELAAQKTLPPEQRRDENASGE"
     PFAM_domain     16725..16934
                     /aSDomain="Inhibitor_G39P"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11417.10"
                     /description="Loader and inhibitor of phage G40P"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1720_0071"
                     /evalue="8.80E-28"
                     /label="ctg1_1720"
                     /locus_tag="ctg1_1720"
                     /protein_end="71"
                     /protein_start="1"
                     /score="96.7"
                     /tool="antismash"
                     /translation="NRNETLKIMAVIKAAYPYYYNNQSEEDLKTVVNLWQGMFEEYEYR
                     LVSGAVRAFIASDTKGFPPSVGMVL"
     CDS             17278..17919
                     /locus_tag="ctg1_1721"
                     /transl_table=11
                     /translation="MQVVNEQDNQAEILRFIEMAKRGDKDMKLAVVNLFKPMAYSMVYR
                     SFYDKEEREEMYQEACLQILEAIEDFDTEKYRHVYFRYYLKNRLRFMISNRIWRIGLEK
                     RRFVYSMDEKTSGVQRGECVKKNQLPSEENTEELAIRGCMTQKVLEVMREKMEQKTYEA
                     VCRHFMEGITYAEIARERGKSRSTVHKQCSRALDRVKRELLGEEDYLRLI"
     aSDomain        17374..17886
                     /aSDomain="TIGR02937"
                     /aSTool="tigrfam"
                     /description="sigma70-ECF: RNA polymerase sigma factor,
                     sigma-70 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1721_0022"
                     /evalue="1.10E-16"
                     /identifier="TIGR02937"
                     /label="ctg1_1721"
                     /locus_tag="ctg1_1721"
                     /protein_end="203"
                     /protein_start="32"
                     /score="58.9"
                     /tool="antismash"
                     /translation="NLFKPMAYSMVYRSFYDKEEREEMYQEACLQILEAIEDFDTEKYR
                     HVYFRYYLKNRLRFMISNRIWRIGLEKRRFVYSMDEKTSGVQRGECVKKNQLPSEENTE
                     ELAIRGCMTQKVLEVMREKMEQKTYEAVCRHFMEGITYAEIARERGKSRSTVHKQCSRA
                     LDRVKREL"
     PFAM_domain     17377..17565
                     /aSDomain="Sigma70_r2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04542.16"
                     /description="Sigma-70 region 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1721_0072"
                     /evalue="2.80E-06"
                     /label="ctg1_1721"
                     /locus_tag="ctg1_1721"
                     /protein_end="96"
                     /protein_start="33"
                     /score="27.1"
                     /tool="antismash"
                     /translation="LFKPMAYSMVYRSFYDKEEREEMYQEACLQILEAIEDFDTEKYRH
                     VYFRYYLKNRLRFMISNR"
     PFAM_domain     17758..17877
                     /aSDomain="Sigma70_r4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04545.18"
                     /description="Sigma-70, region 4"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1721_0073"
                     /evalue="9.50E-06"
                     /label="ctg1_1721"
                     /locus_tag="ctg1_1721"
                     /protein_end="200"
                     /protein_start="160"
                     /score="25.1"
                     /tool="antismash"
                     /translation="YEAVCRHFMEGITYAEIARERGKSRSTVHKQCSRALDRVK"
     CDS             complement(17901..18353)
                     /locus_tag="ctg1_1722"
                     /transl_table=11
                     /translation="MHYEITELSPRTITGITARNNNFSPGSAEVIGGLWQQLYNGVYLG
                     IPDKVNSRTIALYNHYESDEKGDYDITVGCETAPSAPLPQGLSVQTIPGGRYARFRVQG
                     DVQSAVTDFWQALWQLPLDRRFEADFEEYTGTDPQNMTIDIYISLR"
     PFAM_domain     complement(17910..18344)
                     /aSDomain="Cass2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14526.8"
                     /description="Integron-associated effector binding protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1722_0074"
                     /evalue="6.90E-23"
                     /label="ctg1_1722"
                     /locus_tag="ctg1_1722"
                     /protein_end="148"
                     /protein_start="3"
                     /score="81.6"
                     /tool="antismash"
                     /translation="EITELSPRTITGITARNNNFSPGSAEVIGGLWQQLYNGVYLGIPD
                     KVNSRTIALYNHYESDEKGDYDITVGCETAPSAPLPQGLSVQTIPGGRYARFRVQGDVQ
                     SAVTDFWQALWQLPLDRRFEADFEEYTGTDPQNMTIDIYIS"
     CDS             complement(18412..19311)
                     /locus_tag="ctg1_1723"
                     /transl_table=11
                     /translation="MQTHRLFEIIYLLLDKGQMTASELASHFEVSVRTIYRDIDRLSIS
                     GVPIYTNVGKNGGIALMDGYTLDKSILSDAEQNEILMALQSLKAVEYPDPDGLLTKLGT
                     FFKKNQQSWIEVDFTGWGGSIQDRERSEELKNAILNRRTIHFSYWSADGKKSQRTADPI
                     KLLFKGHNWYLQAYCHTRQDYRVFKLFRIQDLQVLGDTFEPYPAVPFTETAKTVMTPLH
                     FTILKNRAYRVYDEFAGAQVTPLPGGDFDVRTCLPVDNWLIGYLLSFGGDLILHSPKPL
                     CATLKEELEKALAHYAQF"
     PFAM_domain     complement(18433..18918)
                     /aSDomain="WYL"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13280.8"
                     /description="WYL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1723_0076"
                     /evalue="5.20E-28"
                     /label="ctg1_1723"
                     /locus_tag="ctg1_1723"
                     /protein_end="293"
                     /protein_start="131"
                     /score="98.4"
                     /tool="antismash"
                     /translation="EELKNAILNRRTIHFSYWSADGKKSQRTADPIKLLFKGHNWYLQA
                     YCHTRQDYRVFKLFRIQDLQVLGDTFEPYPAVPFTETAKTVMTPLHFTILKNRAYRVYD
                     EFAGAQVTPLPGGDFDVRTCLPVDNWLIGYLLSFGGDLILHSPKPLCATLKEELEKAL"
     PFAM_domain     complement(19141..19299)
                     /aSDomain="HTH_11"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08279.14"
                     /description="HTH domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1723_0075"
                     /evalue="9.20E-13"
                     /label="ctg1_1723"
                     /locus_tag="ctg1_1723"
                     /protein_end="57"
                     /protein_start="4"
                     /score="48.0"
                     /tool="antismash"
                     /translation="RLFEIIYLLLDKGQMTASELASHFEVSVRTIYRDIDRLSISGVPI
                     YTNVGKNG"
     CDS             complement(19362..20330)
                     /locus_tag="ctg1_1724"
                     /transl_table=11
                     /translation="MKKFVGIGALIAAAAAVPYLIHKKRQKKLQAEDFNQTESLPLPEK
                     NPWETDFKDEDHLIFCDESNLGKRLIQLENSINIRDIGGYTGLDGRKTKWRKVIRSEEL
                     AHLSDKDVEYFEELGLKHVFDFRDAPKAKALPDKLPSTADYKNIPVLKNIPFSHNEINF
                     TAPDGIDQFMRKIYGYQVENAAPLYAEILKVMTDPNQYPILYHCTNGKDRTGFMTALIL
                     LICGVPEETIISDYSLTNLTFDEAFEILGTIMADEMNEAKGISKDQLKDFFGVKPEWLK
                     IQLNYIKENYENVDAYLLDKTDLTKEDLDKIRENMLEAPSV"
     PFAM_domain     complement(19377..20120)
                     /aSDomain="Y_phosphatase3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13350.8"
                     /description="Tyrosine phosphatase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1724_0077"
                     /evalue="1.30E-62"
                     /label="ctg1_1724"
                     /locus_tag="ctg1_1724"
                     /protein_end="318"
                     /protein_start="70"
                     /score="212.0"
                     /tool="antismash"
                     /translation="IQLENSINIRDIGGYTGLDGRKTKWRKVIRSEELAHLSDKDVEYF
                     EELGLKHVFDFRDAPKAKALPDKLPSTADYKNIPVLKNIPFSHNEINFTAPDGIDQFMR
                     KIYGYQVENAAPLYAEILKVMTDPNQYPILYHCTNGKDRTGFMTALILLICGVPEETII
                     SDYSLTNLTFDEAFEILGTIMADEMNEAKGISKDQLKDFFGVKPEWLKIQLNYIKENYE
                     NVDAYLLDKTDLTKEDLDKIRENMLE"
     CDS             20450..21589
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1725"
                     /sec_met_domain="PF04055 (E-value: 6.2e-22, bitscore: 76.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENVGIYVHVPFCRQKCRYCDFPSWAGLGEAETGRYFEAVCLEIK
                     AFAAEQGRVPAGTVYFGGGTPSYVAADYIGRVMDCIRECFELPEEAIEATIEANPGTLT
                     DAKCRAYRNMGLNRVSMGLQTTSDRGLKALGRIHTYADFKTSLDLLGSAGFENISADLM
                     FGLPGQTLEDVRQDIDRLTALASIKHISCYSLKIEEGTAFDTLYRQGKLLLPDEALERQ
                     MQHTIIDGLAENGFEQYEISNFARKGWESRHNSLYWVMKPYVGFGLGAASYYKEERRTN
                     VMDMEDYCALVTQGKAPVLETHILDAQEKKGDFMFLGLRRMCGVDDADYRELFGSSFFE
                     DFEEIENLVKAGLLTREDQVIRLTPKGQDLANQVFVAFV"
     aSDomain        20465..21523
                     /aSDomain="TIGR00539"
                     /aSTool="tigrfam"
                     /description="hemN_rel: putative oxygen-independent
                     coproporphyrinogen III oxidase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1725_0023"
                     /evalue="8.30E-87"
                     /identifier="TIGR00539"
                     /label="ctg1_1725"
                     /locus_tag="ctg1_1725"
                     /protein_end="358"
                     /protein_start="5"
                     /score="289.5"
                     /tool="antismash"
                     /translation="IYVHVPFCRQKCRYCDFPSWAGLGEAETGRYFEAVCLEIKAFAAE
                     QGRVPAGTVYFGGGTPSYVAADYIGRVMDCIRECFELPEEAIEATIEANPGTLTDAKCR
                     AYRNMGLNRVSMGLQTTSDRGLKALGRIHTYADFKTSLDLLGSAGFENISADLMFGLPG
                     QTLEDVRQDIDRLTALASIKHISCYSLKIEEGTAFDTLYRQGKLLLPDEALERQMQHTI
                     IDGLAENGFEQYEISNFARKGWESRHNSLYWVMKPYVGFGLGAASYYKEERRTNVMDME
                     DYCALVTQGKAPVLETHILDAQEKKGDFMFLGLRRMCGVDDADYRELFGSSFFEDFEEI
                     ENLVKAGLLTRED"
     PFAM_domain     20471..20989
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1725_0078"
                     /evalue="3.40E-21"
                     /label="ctg1_1725"
                     /locus_tag="ctg1_1725"
                     /protein_end="180"
                     /protein_start="7"
                     /score="76.4"
                     /tool="antismash"
                     /translation="VHVPFCRQKCRYCDFPSWAGLGEAETGRYFEAVCLEIKAFAAEQG
                     RVPAGTVYFGGGTPSYVAADYIGRVMDCIRECFELPEEAIEATIEANPGTLTDAKCRAY
                     RNMGLNRVSMGLQTTSDRGLKALGRIHTYADFKTSLDLLGSAGFENISADLMFGLPGQT
                     LEDVRQDIDR"
     PFAM_domain     21386..21553
                     /aSDomain="HemN_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06969.18"
                     /description="HemN C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1725_0079"
                     /evalue="1.30E-11"
                     /label="ctg1_1725"
                     /locus_tag="ctg1_1725"
                     /protein_end="368"
                     /protein_start="312"
                     /score="44.5"
                     /tool="antismash"
                     /translation="DFMFLGLRRMCGVDDADYRELFGSSFFEDFEEIENLVKAGLLTRE
                     DQVIRLTPKGQ"
     CDS             21766..22800
                     /locus_tag="ctg1_1726"
                     /transl_table=11
                     /translation="MDLKERKKKILEVIIKDYINTAEPVGSRTLSKRYNLGISPATIRN
                     EMADLEDLGFLMQPHTSSGRIPTQLAYRYYVDEIMQIQKLAKVVRNDIHNGYLKITREL
                     DNTMNHTAKVLSQLTNYTSVVLSPRVSCFNCKHVQIVPLIKERVLLIVVTYEGMAKNIE
                     MTLSQEIDTTLALKLSNVLNSFLKNISFQEINMELVDQIQELSPDESNLLREILPVLRD
                     TLMEEASDIHSMGLTNLFNYPEFSDVEKIRHLVNVIEEKPLLAGILSSDDTSQVINISI
                     GDENDNENLKEFSIITTTYELEGKTVGAFGVIGPTRMNYDNVSSVLDYIRNELNTNLTK
                     LLMK"
     aSDomain        21778..22776
                     /aSDomain="TIGR00331"
                     /aSTool="tigrfam"
                     /description="hrcA: heat-inducible transcription repressor
                     HrcA"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1726_0024"
                     /evalue="8.60E-99"
                     /identifier="TIGR00331"
                     /label="ctg1_1726"
                     /locus_tag="ctg1_1726"
                     /protein_end="337"
                     /protein_start="4"
                     /score="329.2"
                     /tool="antismash"
                     /translation="ERKKKILEVIIKDYINTAEPVGSRTLSKRYNLGISPATIRNEMAD
                     LEDLGFLMQPHTSSGRIPTQLAYRYYVDEIMQIQKLAKVVRNDIHNGYLKITRELDNTM
                     NHTAKVLSQLTNYTSVVLSPRVSCFNCKHVQIVPLIKERVLLIVVTYEGMAKNIEMTLS
                     QEIDTTLALKLSNVLNSFLKNISFQEINMELVDQIQELSPDESNLLREILPVLRDTLME
                     EASDIHSMGLTNLFNYPEFSDVEKIRHLVNVIEEKPLLAGILSSDDTSQVINISIGDEN
                     DNENLKEFSIITTTYELEGKTVGAFGVIGPTRMNYDNVSSVLDYIRNELNTN"
     PFAM_domain     22078..22734
                     /aSDomain="HrcA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01628.23"
                     /description="HrcA protein C terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1726_0080"
                     /evalue="7.60E-57"
                     /label="ctg1_1726"
                     /locus_tag="ctg1_1726"
                     /protein_end="323"
                     /protein_start="104"
                     /score="192.8"
                     /tool="antismash"
                     /translation="DNTMNHTAKVLSQLTNYTSVVLSPRVSCFNCKHVQIVPLIKERVL
                     LIVVTYEGMAKNIEMTLSQEIDTTLALKLSNVLNSFLKNISFQEINMELVDQIQELSPD
                     ESNLLREILPVLRDTLMEEASDIHSMGLTNLFNYPEFSDVEKIRHLVNVIEEKPLLAGI
                     LSSDDTSQVINISIGDENDNENLKEFSIITTTYELEGKTVGAFGVIGPTRMNYDNV"
     CDS             22809..23369
                     /locus_tag="ctg1_1727"
                     /transl_table=11
                     /translation="MAKEEKMEQNVDETVKEEATEEQTTEEQTAEEAVEDVEKSVNEAA
                     KAEEAAMERLMRLQADFENYKKRTQKEKTDIYQFALEGFVTKLLPVLDNLDRAEAAADD
                     DNTDKYREGVQMVFKQLIGVLNEEGLQEIDCVGTAFDPNFHHGVAVGEDPEKDDQVVLE
                     VFQKGYTFKDKVIRPAMVKVNQK"
     PFAM_domain     22857..23363
                     /aSDomain="GrpE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01025.21"
                     /description="GrpE"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1727_0081"
                     /evalue="6.80E-49"
                     /label="ctg1_1727"
                     /locus_tag="ctg1_1727"
                     /protein_end="185"
                     /protein_start="16"
                     /score="165.8"
                     /tool="antismash"
                     /translation="EEATEEQTTEEQTAEEAVEDVEKSVNEAAKAEEAAMERLMRLQAD
                     FENYKKRTQKEKTDIYQFALEGFVTKLLPVLDNLDRAEAAADDDNTDKYREGVQMVFKQ
                     LIGVLNEEGLQEIDCVGTAFDPNFHHGVAVGEDPEKDDQVVLEVFQKGYTFKDKVIRPA
                     MVKVNQ"
ORIGIN
        1 agacctgtgg ccatgtacaa acgggctgag atacagatgg tggacagtga cgtgttcacc
       61 attgacggcc tggcctttaa gagcagggag attgtggaaa tactaaagcg cgaaagcttt
      121 gtttttccaa acattgtgtc ctgcgggcca gagattgaag ccttctgtgt tgaccgcaaa
      181 aaggtactgg aacagtacat taccatggag ctctgcaatt tcagctgcgc cgtggcacga
      241 gaagctatgt ttaacgccat cagagacgag tttaaaatgg aagagagcac cgagctgttt
      301 ccaggcgaaa agggctggga cctgcagcag ggaatccaga tctttaaaat attctcaaag
      361 gaaaccgaag ggacagggct cagcatatcc gaggcgggcg ttccaaagcc cagccgcagt
      421 gcctacggcc tgatcgtcgg cagctgacaa tggcagacag acaacccaga aagggatggt
      481 acaagctgga caatgcggga accctttatt cctccattgc gtcctccagg gtatcaaccg
      541 tgtttcggat gacactgggt ctcacagaag aagtagaccc cgaggccctg caaaaagctc
      601 tggacaacgt gatggtgcgc tttccgtact ttaacgtcac gctgcgccgg ggctttttct
      661 ggtattacta cgaccattcc gaaaatcgcc ccctggtcga gaaagaatca cactatccct
      721 gcaaaaccat ccggcagcga aagggcgtgt ttccattccg gattctgtac tatggccgtt
      781 atatccattt ggaaatgagc cattccatct gtgacggcta cggtggttta gcttttttaa
      841 agccgcttgt attagaatat tttaaagtaa aggacggcat tgtctgcaag gagctgggcg
      901 acatcatcga tattaacagc ccggtcgacc ccgaggaata cgaggacgcc tttaaaaaat
      961 attatgaaaa acgggttccg ccgccggaaa agggggagaa ggcctaccat ttcccctttg
     1021 gcctgctgga taaggggcag tacctgctgc tgaccggcat tgtaccagtg aaagaggtgc
     1081 tggtacagtc aagggcccac aaatgcaccc tgacgcagtt tatcacagcc ctttactttg
     1141 agagtatcca ggagtatatc ctgggcctcg agaaaaagaa acgcgcccgg tctggccata
     1201 ccaaggccaa tattgccatc aatgtgccgg tggatctgcg agcctttttt ccgtccaaaa
     1261 ccctgcggaa tttttttatc agcctgaacc cggccattga tatgcagctg ggggtttaca
     1321 gcctggaaga gattatcgac cagatcaagg ggtatatggg cctgtatatc aaccagaaaa
     1381 acatcaaccg ctatgtttcc agaaacgtgc ggaacgaaga gctcatggtg ctgcgcatga
     1441 tcccgctgtg ggtaaagcgc gtgattatgc ccattgtgta caagcgctac ggcgaaagaa
     1501 gctacaccag ctcagtcagc aacctgggaa gcatctggat gcccgaggag gtccgggaca
     1561 ggattaccgg gttcgagata ttcccgccgc ccagcgccgg aaataagcta aaaattgtga
     1621 tggccagcta tggcgataag ctgtatatct cctttggaaa gaccactggg gaaaaggaca
     1681 tcgagcggat ttttttcaga aagctgcgaa agctgggaat cccggtacga atcgaaggaa
     1741 accagatcaa ttattacgaa gtcgaaaagg aggatgccta atggcctatt gtccaaaatg
     1801 cggtgttgag gtcgataata acgtcaaaaa ctgcccgctg tgcgattttc caatacccga
     1861 tatcggcgag gagccaaagg gcgaaaagcg ctatcccctg gcggtcaaca cctatccgca
     1921 ggaacatcag gagaagaaga accggatttt ttacgccctg gaaattattg tggcggcagt
     1981 atttttaatt aatatggtgt tatactggtt tatccctttt aatccgacca ttactcagat
     2041 cattatgata tcatccgttt ccctggcgct gtatctgatg ttttgcttta attatctgcc
     2101 agcgctggtg aaccttttgg gctgttattt taccacgctg ctcctgggtt ctattattta
     2161 tgtgattgtg ggcggttcgg gagactggtt tgtaaattac gccatgccaa tcgtgacgat
     2221 tctttttatc gacattctca tttttggtat catctataaa aagaaccgtc accgaaatca
     2281 attcatctac gcgccagtgt ttttgattgc tttcagcgct acactgtgcc tggggattga
     2341 cggtgtgatt tcctataaca ttctggggca cctgcgcttt acctggtccc tgatcgtggc
     2401 gatctccggc atctgcatta tcgccctgct catggggatt taccacggcg tgcccgaccg
     2461 caccaaggca tacctgaaga aaaaactgca tgtatagagg aggcggaaag tgaaaagaca
     2521 agaaaaaatc gaggcgcgtc tcctggaaat gcccctttac gactatgcct ttttcccggt
     2581 aaaggatatt attttcacac aggatgtacg caccatctgc gccatgaacg actgcggcat
     2641 gtacggcagg cgctgggtct gcccgccggt catcggcagc attgaggact gcattgccga
     2701 gtgccaggcc tatgagcacg cctttctctt ctcgaccgta accgaggtgg cagattcctt
     2761 tgacctcaag gcctgcgttg aagccagagg cgaccatgag gccattacct acgaggtcgc
     2821 ccagatcttc aggcaggaga ccgaaaaccc gctcattctg tcaacaggct gcattccctg
     2881 tgagcactgc gcttacccag acgcgccctg ccgccacccc gaaagggcct ttaaaaccat
     2941 tgagagccac ggcattatga ttatgcagat ggcagcccag cagggcctga attacgactg
     3001 cggacagaac atcgtgacct acttttcact ggttttgtac aatctttagc caagagcgtt
     3061 gagcggcttg agaaatgggt aaaaccattg tataatagaa atagttctaa acaaggagga
     3121 atcgatatgc agccacagga aaaagcagtc tatcaggaca tactgcaatg catttttgcc
     3181 agatatctgg aagattactc ggaaaacacg tattcagaat tattaaaaaa atacacaggc
     3241 ctctcagtca tcgaaaccgg cgaagccaga gaagcctcct atgagatggt ccttcagctt
     3301 ctgaagcgga gaaccaggcg ttataccggc cttgggcgca tggctgaggg cgacgcccgg
     3361 gaagaaaaca tcctgtatcc cgccgccttc gagacccagg gcgccgatcc agagctcgcc
     3421 cgtgagaccg actacggcac agcctgggac ggctttgaca atatgctcct ggagctgcca
     3481 gaggaaaagg aggtcgaatg taaaatggca ttaaacagcc tggaaagcat tatccacgat
     3541 ccctccatga ccaaaccgca gaaggagctg ctgtcaagca ttctgctgga ctggatcgcc
     3601 catgagccag aggatatcgg tatcctgttt gtccccatac tgctgcaaat ttatgaataa
     3661 tagacaaagc ccaatccgcc gtccggttta gacagaaccg gcggtgtttt tttgtacaaa
     3721 aaattgcatt ttttacgtat atcttttcag agataaaggt gatataatgg agataaatta
     3781 aatatcggtt gcgctattgt tgattttaaa cgtgttcatt caaattttct ttcattctga
     3841 tttcagatgt cccataaaag ctgataaaag aaatgaagaa aagagttttt aaagcctgaa
     3901 aggcagaaag gaaaccgaaa tgaaagccga tcttgtccgc attgcgctga ttccgtattt
     3961 tgtcctgctg ctggttatct gcaactggaa tgtgaagctg tactcagccg taacactgaa
     4021 cagcttttac tttctggaat atattctttt tattttctgc ggcctggcga tcgcacgctt
     4081 aatggatgtt tcccagagca cctatcgtca gaaaagcgcc cgaatcatca ttattgtcaa
     4141 tcttgttgtt ctgctgggat tctttctgct gggattcctt cggatttttg ttttctttga
     4201 cgtccgctat ttttatcaga tttcttttct gctctttggt tactatgtgt atttgctcgt
     4261 tataagtctg agaaagggtg agaatccatg aaaaagtatg tgcgaaacgg gatgatcatc
     4321 tgcgcgctgt cgccgctgat cgcctattat ttacatttta tggttggtac ggtgtccagc
     4381 cgtatcttta tgccgctgtc ttacatctca aacaaccccg ccattgccta tctgggatac
     4441 aacggtgggg tggaaatggt accagcctgg accatcgctg tcaatgtgac tgtgctcatc
     4501 tatctggctt accggaggga gacggataaa aagaagggag aggagccatg agggcagtac
     4561 aggctgtgtg cctcccctga gtaatgaaaa gcggccaatg tcatttctat tgttaaaaaa
     4621 ggaggacata aaatgcaata tcaaaaatta tcataccctg caaaaaatta cgccagtgag
     4681 ctgtttgaag aataccggaa ccgtctaaaa gagaatatac ctgacgaaaa agcgtcggtt
     4741 atcaacttta aaccggatat gaacagcacg cgctatatct gcgagcttca aaaattcttt
     4801 cattttcagg taaaggaaaa tcaggtgatc attaaccggt tctttgtgga ccagatgaca
     4861 tgcttttata agtggtaagg aagtaaagga aaagtttcag cctgagagga aaacaatgaa
     4921 aaataagata tgtttagtct atctggcggt agttccgtac cttattctgg cgatggtcac
     4981 tgtacactgg tatgagtatt acaggccaag cccgtccacg ctggcatttg aacccttttt
     5041 gtttgttttc aaaattttga tgtaccctgt catcggggtt ctcctggctc tcctgcacat
     5101 tattcccaaa agtgtgtatg gtacaaaatg ggcaagaagc attatggctg tcaattttat
     5161 ggtaccaatt gcattttggg ccatctatta ctctgacttt ggcggactgg gcgtgagaat
     5221 gctgtttttt atcaaggtac cggtatttac gaccttatcc tttctattaa taggctatta
     5281 cctagttttg ttaatgatga gttttaaaaa aggatagtga aatgaaagga aaagtaatat
     5341 taattatttt tagtttggct gttttaacag gcctgtacta tgttgtggga gatgatctgt
     5401 ggaggagtct gacagcctcc tttttcttca cagctatttc cgtttcagta tgtgtacagt
     5461 tcattgagct cataaaaaag tacgaaatta aaagatgaga ggtcaaaagt gaaaaagaaa
     5521 ttattgacag tgctcgcgct gctggcagtc tgctgcttaa tgtttttggg ctgctcagaa
     5581 aaggaaaagg cgagtgagga aatccctctg tccgaaagga gtattgagga gcaggttcaa
     5641 aatggccgga gcgacatatt taaagaatac gataatatca aggcctttag agccgtgtat
     5701 caaaatgatc tgagaaccat gaacgggctg gtagatcctc ataaatatga tattgttttg
     5761 aaaaatcttg agtatgagta cccacagatt caggagtctt caaaggtaac ggcaacctat
     5821 aaaaagattg acaaggataa atatgtgctg aagtattacg attcatttga agaatacggc
     5881 gaattaaaag aaagcgacct ggcagccctg aacgaatccg gcaaggcgca ggggatcacc
     5941 tacaagtcca aaatggcaga acttgtgcca gagcaggaaa atatccgggc ctattatgag
     6001 aaggtggtct gaaaaattag aaggattgag gacaggaggt gcgcaaaatg agagataccg
     6061 ttaaaaacag tgtgagctgt gtggtctaca gtgtcatcat tgtagtggat atcgtgctta
     6121 actatcagct tttccactgg ctgagcaagc ctctttacag aattaatgaa agacttttcg
     6181 gccctacaga actgggcctt aaaggccagc cgccctttgt ggtctttttc cagttcttta
     6241 ttcccgtcat tctgtttttt gtcattgtga tggccggata ttttctctgt aagaaaattg
     6301 aggaaaagaa aaaccgataa aaatgacctt tatctttaaa aaaagagcgt ttgcagaata
     6361 cgaggaggaa agtccatgaa agtgaaagca tatttaaaca gactgttgcg ggaagaatcc
     6421 agtagtatgt ggggtgtccg ccttataatc aaaatcattt tggtgcttct ggttctgaca
     6481 gtatacgcac ttctgaacac actggtactc gaaagcatat ccgatagggc ctatgctctg
     6541 atcaatcctg aattagaaaa caatatggtg ctttatcatt atgttttttc cccggcggtt
     6601 atcctggcac tggtgctctc aatggtatgg atcagtaagg actttaaact gaaaagaaga
     6661 agcaaggtaa aaaaggacag cattgttatc gggctaattc tgtttgcgtt atatatgatt
     6721 ctttatctcc catacatttt ttatagtttt caatcctcag cgttttttgt cagaatggta
     6781 cttttctttc tgtccaaagg agcgaatcgg gcatttttac aggtgctgtt actgctgtcg
     6841 gggtacttta tcataaatgg ggttgttagg gctccagttg tgggagataa aaattgattg
     6901 agcgaaaagc agtgggaaac cgttgttttg agtaaagaaa aatcagtagt ggacatctca
     6961 gacggttctt tattgctaaa agagaaaaac gacaagataa tcatattttg tgattatacc
     7021 agttaaattt gcgagatagc cgaaagatct tttatggcag gcttaacatg ctatatttgt
     7081 ttttaacaag attaaaggta gatatctagc gctaaaaagg taccatttgc tttgaatgtg
     7141 atttttttaa gggataaaac cccacgagaa aggagaaaaa atgaaaaaga aattgtttgt
     7201 aatgatgctg gcattgctgg ttttctcttt gccattgtca ggatgcacgc cagataaaga
     7261 agacgtacag aaagaaaaca aagcggaaaa aaccatggaa gaacaagtag agaacaatca
     7321 gaacgcgatt tttaaacagt acgacaacat caaggcattc cggtcggaat accaaaagga
     7381 tctggagaca atgaacgcgc ttgtggaccc gaataaagcg gaaatcgttc tgagcgatat
     7441 cagctataca gcaggcgcgc ccagctccga ttcaaaagtc gatgccacct acaggcgaat
     7501 taataaggag acctatgttc taaaatacta tgaatcctgg gatgtgtata atgaacaggt
     7561 aaaaaacgat ttgtcagcac tcaatgaatc ggttaaggac cagggaatcg aataccgtat
     7621 agaccgcgcg gagctggtgc cagaggataa cagagtgcgg gcttattttg agaaagtgac
     7681 ataaacgctt ttataaacaa cgggtaaatt atagaaaaga cagaaagtac gggctttctg
     7741 tcttttttat atgtctaaaa aatatataga tatcttttat aagttgaaaa tgttataata
     7801 aaataaagcg taaatcaatg gatggagaga ggaggtcttg aaaatgttcc gtattggggt
     7861 gtgtgatgat gaagcttatt tccgacaggt tttagaaaaa cagctgatga cttatttaaa
     7921 attttatgaa cagaaagcag aagtttgcct ttttgaaaat ggaagcgatt ttttaaaggc
     7981 ggctggagat caggccttta atcttgtttt tcttgatatt gagatggaag cggaagaaac
     8041 gggaataaaa gtagctgaaa gtttacagaa agaaagtcct gacacactgg ttatttttgt
     8101 aacctctcac agtgaatatg ttccgagatc gtttcgtgtc aatgcgtttc aatatttaac
     8161 aaagccagta aaaacagagc ttatcactga agagattgaa agggcaatgc gctatataaa
     8221 aacccaaaga agccgttatg aaatcaactg gaacggaaaa caatacttta ttctaataaa
     8281 aaaaattcgt tatgtggaga cagataaggg ccataatgta gtggtgcata ctattgagga
     8341 aaattataaa acgaaacgaa gtttaaatga tgttgaggat gatctgaagc cttatggctt
     8401 tctccgtatc catcgcagtg ttttaattaa tatgaatttt atctgcggca aacgagataa
     8461 ggaaatatgt atccagaaaa aaccagagga aatttggctg tctgtcagcc gtgataggca
     8521 gaaaactgtg gatgccgcct atattagctg gcggagaaag tcgagtatat agtgatgatt
     8581 ttaaaactga tctgtgaatc gatgattgcc ggatttgagg ttgtattgat ttatttttgg
     8641 gcaaaagcct tttcagatga aaaggctgag cgctggcagg tggtggtggc cgcgtctgtc
     8701 atttttatat tgatattgag cgtgtcaatg attagttttc agccgtttgt attaataaca
     8761 aacgcgacta tctgtacttt tattatgctt tgggtaatga accggcgaat taaaattaat
     8821 ttttggctga cgctgtgttt ttcgacatta atgtttctca gtgagactat tggcgggatg
     8881 ctttatgctt ttattgggaa tgttgatttt aacgcgacgc gtttcgatcc attgtaccgg
     8941 ctgcgtgcaa atattatttc agaattagtg gcctttacga ttattcgaat tatcagtgtc
     9001 cgtcagcgtc attcctttta ttttccacct ttaagaatta tattgcagat cgttgttttg
     9061 ccgttaacga gcattctggc ggtagtggaa atgggcttag gacaggccgg tgcctatgaa
     9121 attggcggca ttgtatttaa ccttgccatc attgccgggc tggcgatggc aaatatcttt
     9181 gcgttttatc tttttgaacg ggaacagctc tataccgaac aaaagcaaaa agaagccctg
     9241 tatcgccagc agcttgaata ccagaaggaa tcctaccgga atttgaccac ttcgcaaaat
     9301 gaagttcgaa aaatccgcca cgacttaaaa aatactttaa cggccgtttc cggctatctg
     9361 aaagctggag tgacagaaaa ggccgaggat ctgctggaag caatggtaac ggatttgaaa
     9421 aaaacagagc aagctgttta tacgggctat ccggcggtgg acgcggtcgt ttttgccaaa
     9481 gccagccgga tggaacggga caaaattcct ttttcgaaaa cgttgatctt gcccgaaacg
     9541 ctgccaatca gcgaggagga tctttttatt cttttaggtt cagctttgga taacgccatt
     9601 gaggcctgcg aaaagatcga aagggaagga cggtatgtcc tgctgaaaac aggttttgat
     9661 gaacgtcgct tttggatctg gattgaaaac gccgcaaagc tgaccgagga ggaacaggca
     9721 ggccgtttgt cgacccgtaa ggctgataaa aaaagccatg gattaggcct gttgaccata
     9781 cagaaaatcg tggagaaata caacggtatg tggcagataa agccggaaaa acttaaattt
     9841 acgttgaata ttgagttttt tctttaggcc gttttacaga aactgattca cagacggcag
     9901 aaactgccga ccccattgta aagcataaaa aatcatgtta gagttgactt gtaaaaacct
     9961 ttacagtcaa ttcttttttt tatgaaaggg gaaatttgaa atgaaaaaga aattaatgga
    10021 gtatgcgttt aagtatggca gtatgatttc agccctggct ttgatgatcg gtgtttccgc
    10081 tggaggtgca gcctgttggg gatggcagta tcagccaaaa gagccagaag ggatgaggaa
    10141 gtttaagaga aatttggatt gaacaattca aatgcagtgt aatggaggag gtgggtccgt
    10201 tggaaagtga tatgaaggat aattggagat gtttttacac aggattcaaa taaagaagga
    10261 gaaagaaatg aaaaaagtat taagtaaagc tagtttaggt attgtagtta tgttgttaat
    10321 gctaagcttt gcgggaagtg catttgcagc aagtgaagcc gatgaacaaa ttatccagcc
    10381 aagatcagag aatgtatttt ttagttttcc agtgtcaggt acaagcggta gatgtacagg
    10441 agaggcattg aagcattcga cttatacacc atactgggtt caatttaatt ggtcaagtgc
    10501 ctctaataat atcattttaa atactgttat gcataattcg gatcatgcat cccgtggaca
    10561 aggaaaggtt ttggaaggaa catcagcttc cattgcaagt actggaacag catattatta
    10621 ttatcacggg aatttgtgga gagaatttga gtgggatcca gctgttagtg taagtggtta
    10681 tttttctcca gacaattatt aaatacagta agataccaag cacttcttaa gaagtgcttg
    10741 gtaatcctta ataattcaga aaggattgaa aatatgaaaa aaatatttat attgtttatt
    10801 tcgattatgg ttcttttatc tgtaacagct tgtagtatta caggcaaaat agatgaaccc
    10861 aaatggcccg atgaaacaac aaaggaatat attgaaaaag tagaaaatga gctaaattaa
    10921 aaatgagagg aaaaaatgga aattacaaag tataggtggt ttcataaata tagaataata
    10981 gttttaagta ttttttttct aggactttgg ataagctggt acctattagg aaatatttac
    11041 ggtgttacat tgggctttga tatggctgct cctgatttag gagaaaacgt acaggctatt
    11101 aaacagaacc tcttagggca attgttaacg atagatcatt ttgtttcatc gaccttcagg
    11161 ttttcaatga ttttaggccc tgtacttatc tgtgcaaata cgttgttatt tatttgggaa
    11221 aaaaaaggtt acttagcttt taagttgcca aggaaaaata attataaagg ggtcataata
    11281 aatacaatac tgattcatgc atttatcaat gggactacct tttactttgt atatattctt
    11341 tttttatctt taggcatgtt gtttaatgcc gcgcatatgg aaattgcgag gacttctttt
    11401 gattttttat ttggcagaaa tttttctatt gaatctccgt atttctacta tgttttagat
    11461 ggatttatta aattttttgt atttggtttt gtgtacagtt tattttctaa tacgattgca
    11521 ttagttagtt ctaaaagtta tgtgtcggtt ataattccga ttatttatta ttttggtttt
    11581 tcagttatat ttgcaactgg attacagtat atgcctttgg cacctgtcta tacccaaggt
    11641 tttacttcat ttgttgatat gcctttatgg atggccttta caccaatgat tataccagta
    11701 gttacttctt tttttatcat aatttggttt ttaaaaagaa aggaaaaata tgtggattaa
    11761 aatatttgct gtaataatcc tttggatgtt ttatatttac tacgatccaa tgggaccttt
    11821 tggtggactg tttggtgaca tgggctcagg tatgttagtg acctatttat gctatttctt
    11881 tatagccatg catttatcat ttaatagaat aaactccttc atattaagtc gttttgtgtt
    11941 taaaaaagat ttctacttct gggcattaaa aaagatatta aaagttagct ctctgtatgt
    12001 attgatctgt acatttacat atgtgtttat taattatata ttaaggcaca atgatatggt
    12061 aacaatttac ataattgtaa agtttatgac tggaagtatt attaatatat ctttattaaa
    12121 ctttattata ttgctaatta aacttcagta caacacaatt tttagtatga tatttgcagg
    12181 atgtatcatt acattggctt atattactgg tggggttcaa ttgataagat ataatatcag
    12241 ttttatagcc tcggcatata cggatattaa cggatatatg cgtcctatgt ttactattat
    12301 gggatatctt ataatcctaa gtattatgtt gatattattg tcaagaaata aaaagatgga
    12361 tataagtatt taattatgaa aataaaaagt atttcgtttt tttgtgcaac attgctgaca
    12421 ctagaaatta atatttggag aaatgtacaa gataataaaa aaatagaaga tattataaaa
    12481 attatttttt tatcggacaa tgatgaaaca ggaataagta ttacatcgct tattacttgt
    12541 tttgcttttg ttatattttc agtactattt gtaattaata ttaaaaatga tatctcaaaa
    12601 aattatagaa gtatgatact ccaaagatat agaagtcgga gaagcttttt gatgcagcat
    12661 caaaaaaagg gaattcaaaa cagtttaatt ttaacaattt ctatttttgt atgtttagtt
    12721 ttattttata gtatattgga attcaaactt ataaatttag aatcgctacc gggcgaccaa
    12781 ttaatgtcct tatttattaa tatttttttg tttttaaata tttcaattac ttttaataca
    12841 attattgtct taaaaaagag caatatacaa ggaataactg cgaatattct tttaatagtt
    12901 attgttatat tattagatat ttcaattaaa gagattagta tactaacttt tggatcaatc
    12961 attctattgg taagaggaac tgttttctta tcaaacataa tttttgtttt aataatatat
    13021 ctatattttt ttataaaaaa tatagatatc ctttaaagga gaagacaatg caatcaatta
    13081 ttcaaataga aaaagcatca aagactttta aagataaaag cgtttttaag gatgttaata
    13141 tttcaataca aaaaggaagt tgtataggtt tttctgggta caatggatgc ggtaaaagcg
    13201 ttctcttgaa atgcatttgt ggattttcgt tactaaacca aggaagaatt atatgtaaca
    13261 acaagacaat taataaggat atagatttta ttcaagatac tgggataatt atcgaaactc
    13321 cagaatttat aaacgacctg acaggctata aaaatttaaa aattatagcg gaaattcgga
    13381 atgtaataga cgataaagat atcctgaaaa caatggaaat tctcgactta gaaaaagata
    13441 aagataagaa agttggtaag tattcccttg gtatgaagca aaagttaaga attgcacaag
    13501 caattatgga aaaacctaaa attttaatcc ttgatgaacc tacaaatgga ttagacaaaa
    13561 gaagcgttgt aatcgttcgg gaaattttaa aaaaatttat aaaaaagggg ggaactctag
    13621 tgatgacaag ccacaataaa gaagacatgg acattctatg tgatcaagtc tatgagtatg
    13681 ataattataa tttttatatg aagagtaaat gaagagaaag ccaactaaca atgctccctg
    13741 gcaaaacacc gacttcatca aaaattcaaa atttagctcg aagattgaag atccttgcca
    13801 gactgcttga cactccttag aaaagctaaa gcagaatctc tggcactaaa ttacagtaaa
    13861 aaagtaggag gcccccccat gatccacaac ctatcccaaa aactaacgtc caccttcatc
    13921 caccaccgca tcattgacgc tgaggaccgg gaggtttata tttacagctt tgagctcctg
    13981 ctgtccgcgg tcgtcaatct ggcggtggtg gtgcttttaa tatgcctcac cgggcaggtg
    14041 tggggtggcg tgggttttgt tttggccttt ctggtgctcc ggcagtccgc gggagggtat
    14101 cacgcgtcct cacatttttt ctgtatcctg agctttacgg tcattttttt ggtgtttctg
    14161 gcagtgatca tttttctgcc gccgctttac tatctgccgg ttattctggg ggccttaatc
    14221 atcggtatac ccgtcattgt gctcacagcg ccggtggccc atgagaacaa gccgctgacc
    14281 ggggcggagc gcgcgcgcct gagccgtctg gcaaagctga ccgtggttgt tttaacagct
    14341 ctgatcatga cgggctggta cttggcgcct tggaacgcgg cgccggctgg agcggccctg
    14401 gggcttctga cggttgcgct gtcgtccctg gcggcgctgt atcaaaagag aaagcgggat
    14461 taagcccgcc ctaactaaat attgagactg ggataatgct tgacacccgc caacagagag
    14521 cttttgcttt ctgttatttt tttgctctaa ataaagagag aaggagttat tatgaataaa
    14581 aaagatttgt atgcagtgct taaagataaa acccgtatag cctgggtgga ggtttttacc
    14641 gacccggaag ccggggatgg ccttcgggtc tggtttgagg actggcgggg gctggagttc
    14701 taccggagta aggcaacctt tataaaatgg ctggaggaat gggatatcgt gagcacagcg
    14761 gcggcagaaa aggcggcgag ggcgcttctg ccgggcagcc agcttctgcc catgtaccgc
    14821 ggcccaaaat gtacctttgt ccagattaag accaaatcga ccaaagccgg ggagaagtat
    14881 gcctatagct gggtaaattt ggatttaatt aattaacggc cccgggcctg taaaggaggc
    14941 gaaatgcctg gagcttaaaa acggcatgat cgtgcgccat ctgcaccggg atgccaccat
    15001 aaggcgcaag ctggaggagg cgtggcaggt ggcggctgcg ctggaaaaaa gatgaaaaag
    15061 gtgtgtgttt gtcccataag tgcaaaataa tatccgatat acagccgaaa aagccatatt
    15121 ttaccctttt ttgctggttt acgcggccaa cccgcggttt gcggcattgg ccagcgcccg
    15181 gtataataca cctacaagct tgaaaaacaa aggacaccgg tgttccgaaa ggaacgatta
    15241 aatgaacaat aaaataaaca gaatggtagt cacacccgag gagctgaagg atcagccggt
    15301 tatatctaca ctggaccagc tgttctgcat ggagctcatg gatttgcaga tgaaccggga
    15361 ggaattatta agggcatatt ataaccgcac gctgtttctg ggcaagtcgc cggagcagcc
    15421 tgtgacggtg gtgtatggta cgggcgccac cccctactac aatatccgcg aggcagcggc
    15481 gcttatggga aagcgagaag gtattgacgc ttttatcgca gagcacggcg atgcgctggg
    15541 cgtgaccatg cgtattgcgg cggcgccgga caggctgggg ctgctcgaat ttctgcccac
    15601 ggcggacatc gaggggattc atcgcctggc agcgctgctg ggaaaagaag cggattcgga
    15661 gggcgtagcc atcatgtttg agctgttaga ggaaaaggct gtggcctggg ggagacagtg
    15721 ctatgcataa gtttaccatt acagacacaa cctgctatga tgcgctctgg ctgccgggcc
    15781 ttgagacaat accggcggtc attgacccgc cgatgtatta cggcggagag ccagagatat
    15841 ggctggcgct gagcccgatc ctgcctctgc tcggccagac ctcagccagc aagctggccg
    15901 ggctcatcgc tccggggagc aagtgcaagc gccgggtgta ttttggggga aggcaccgcc
    15961 acatgtggat ggtgaacatg caggggctgc gcggtctgct gctgtttata aaggacgatg
    16021 tgaaaatgga atgggcgaag gagcagtttg aacgaaaggt acacgccctg gaaatgctgc
    16081 ataaggggga cgcaaagacc tccatccttt accactatga ggaggggagt gaaccggttc
    16141 cagccgagga atacggctgt gaggccggga cactggcccg cgtgctgatc gatcagcacc
    16201 gccgatgcca aaagctggag gagatgctgg agcaggtgga gaatggggct taactacctg
    16261 gcggagctca acgccatgcg ggattatctg ctgctgaggc ctctggcctc cgggcagata
    16321 tccctgtggc acgggctcat gatgatcaat aacctctgtg gctggaagag ctggtttaca
    16381 gcgccgaata tgacgctgca ggctttttcg gggctttcgg acagtggaat ccataaggcg
    16441 cggaaggtgc ttaaagagag ggagctcatt gactacctgc ccggctcgtc tggcgtgata
    16501 ccggcaaaat atcacattta tccggtatcc ctgcgggtcc gggaggcgcg cggcagtaaa
    16561 gacagcagta caggcagtag tacaagcagg agtacaggcg gcggtgcggg cagtgggaca
    16621 ggcggcagta ccgcattcta taaacaaaac aaaccagaca aaaagagaca aaaggaaacc
    16681 accaatcctt ttttaaaaat gttaagcgat gaggaggaaa tgtgaaccga aacgaaacac
    16741 tgaaaattat ggctgtcatc aaggcagcct atccctatta ttacaataac cagtcggagg
    16801 aggacctgaa aactgtggtc aacctctggc aggggatgtt tgaggagtat gagtacagac
    16861 tggtatccgg tgcggtacgg gcctttatcg ccagtgacac taagggtttt ccgccctctg
    16921 tgggcatggt tctggacaag ctgaggctgc tcaccgcgcc gcgtgagctc tcggaaatgg
    16981 aggcctggaa ccagctttcc agggcggtta aaaattcggc ctggtacgcc gaggaggaat
    17041 tcgacaagct gccggaggat atccgcggca ttgtgggctc tccggccagc ctccgggagt
    17101 gggcattgat ggaggcgggc accttccact cggtcattca gtccaatttc atgcgcagct
    17161 accgggcctg ccgggggcgt aaacgcgccc ttgaggagct tccggaaagt gtgcgcggca
    17221 tgatcgggga gctggccgct cagaaaaccc tgccgcctga gcagaggagg gatgaaaatg
    17281 caagtggtga atgagcagga taaccaggct gagatcctcc gctttatcga gatggctaag
    17341 cggggcgaca aggacatgaa gctggcagtg gtcaatcttt tcaagcccat ggcttacagc
    17401 atggtttacc ggtcctttta tgataaagag gagcgggagg aaatgtacca ggaggcctgc
    17461 ttgcagatat tggaggccat tgaggatttt gatacggaaa agtaccggca tgtgtatttc
    17521 cggtattacc ttaaaaaccg tctgcggttt atgatttcaa accggatttg gcgcattgga
    17581 cttgagaaaa ggcggtttgt ctattcgatg gatgaaaaaa catccggagt ccagagaggg
    17641 gagtgcgtga aaaagaacca gcttccgtct gaggagaata cggaggagct ggccatcaga
    17701 ggctgtatga cgcagaaggt gctggaggtg atgcgagaaa agatggagca gaaaacctat
    17761 gaggcggtct gccggcattt catggaaggt atcacctacg ccgagattgc cagggaaagg
    17821 gggaagagcc gctccactgt ccataaacag tgcagccgtg cgctggacag ggtgaagcgg
    17881 gaactgctcg gggaggagga ttatctgaga ctgatataaa tatcaatggt catgttctgc
    17941 ggatcagtgc cagtgtactc ctcgaaatcg gcctcaaagc gacggtcaag cggaagctgc
    18001 cacaaagcct gccagaaatc tgtgacggcg gactgtacgt cgccctgaac gcggaaacgg
    18061 gcgtatctgc caccggggat ggtctggaca gatagtccct ggggcagagg tgcgctgggg
    18121 gctgtttcac agccgacggt aatgtcataa tcgccttttt cgtcactttc gtagtggttg
    18181 taaagggcga tggtccggct gttgaccttg tcgggtatgc ccaaatatac cccgttgtac
    18241 agctgctgcc agaggccgcc gatgacttcg gcggagcctg gcgagaagtt attattgcgg
    18301 gcggtaatgc cggtgatggt tcttgggctc agttctgtta tttcgtaatg catgttatac
    18361 ctcttttctt atgatagaac cagtatagca gatgaaatat gacagggtgt gtcagaattg
    18421 ggcgtaatgg gccagagctt tttcaagctc ctctttcagg gtggcgcaga ggggtttggg
    18481 ggaatggagg atcaggtcgc cgccaaagga aagaaggtag cctatgagcc agttgtccac
    18541 aggcagacag gtgcgcacgt caaaatcgcc cccgggcagc ggggtgacct gggcaccggc
    18601 gaactcgtcg taaacccggt aggcccggtt tttaaggatg gtgaagtgga gcggggtcat
    18661 gacggtttta gctgtttcgg taaaggggac ggcgggatag ggctcaaagg tgtcccccag
    18721 aacctgcaga tcctggatgc ggaacagctt gaacacgcgg tagtcctgtc tcgtatggca
    18781 gtaggcctga agataccagt tgtggccttt gaacagcagc ttgatgggat cagcggtgcg
    18841 ctggcttttc ttcccgtcgg cgctccagta ggaaaagtgg atggtgcgcc ggttgagaat
    18901 ggcgtttttg agctcctctg agcgctcccg gtcctgtatg gagccgcccc agcccgtaaa
    18961 gtccacctcg atccagcttt gctggttctt tttaaaaaaa gttcccagct tggtgagcag
    19021 gccgtcaggg tcagggtact cgacggcttt aaggctttga agggccatga ggatttcatt
    19081 ctgctcagcg tcgctcagaa tggacttatc cagggtgtag ccgtccatga gggcgatacc
    19141 gccgtttttt cccacgttgg tgtaaatggg gacgccgcta atgctcaggc ggtcaatgtc
    19201 ccggtaaatg gtgcggacag agacctcaaa atggcttgcc agctcgctgg cggtcatctg
    19261 ccccttgtcc agaagcaggt agataatttc gaacaggcga tgggtctgca taatgtttct
    19321 ccaattaaaa tggacggcag atctgccgtc cgttttgttt tttatacgct tggcgcttcc
    19381 agcatgtttt cgcggatttt atccagatct tcttttgtca gatcggtttt atcaagcagg
    19441 taagcgtcga cattttcgta gttttccttg atgtagttca gctgaatctt cagccattcg
    19501 ggcttgacgc caaagaaatc tttgagctgg tctttggaaa tacccttggc ctcgttcatt
    19561 tcatcggcca tgatggtgcc gagaatctcg aaggcttcat caaaggtcag gttggtcagg
    19621 gagtaatccg agataatggt ttcctccggc acaccgcaga tcagcaggat gagggcagtc
    19681 atgaagccgg tgcggtcctt tccgttggtg cagtggtaca ggatggggta ttggttgggg
    19741 tcggtcatga ccttgaggat ttctgcgtag agcggcgcgg cgttttcgac ctggtagccg
    19801 tagatcttgc gcatgaactg atcgatgccg tcaggcgctg taaagttgat ctcgttgtgg
    19861 ctgaagggga tatttttgag caccggaatg tttttgtaat ctgcggtgga gggcagcttg
    19921 tctggcaggg ctttggcttt gggcgcgtct ctgaagtcaa agacatgctt gagtccaagc
    19981 tcctcaaagt attccacatc cttatcggaa aggtgcgcca gctcttcgct gcggatcacc
    20041 ttgcgccatt ttgtcttgcg tccgtccagg ccggtatagc cgccgatatc gcggatattg
    20101 atggaatttt ccagctggat cagccgcttg cccaggttgg actcgtcaca gaagatcaga
    20161 tggtcttcgt ccttaaaatc ggtttcccag ggattttttt ccggaagcgg aaggctctcg
    20221 gtctggttaa aatcttctgc ctgaagcttt ttctgacgtt ttttatgaat cagatatggg
    20281 actgcggcag ccgcggcaat aagcgcccca atgcctacaa attttttcat atgttcactc
    20341 ctttgactct ttctacttta ttatatagaa tatattgtaa cataaagact taaatttgtc
    20401 ccggtgacaa tttgtttttt cagcatattt tataaaaagg agcgttttaa tggaaaatgt
    20461 cggaatttat gtgcatgtcc ccttctgccg gcagaagtgc cgctactgtg attttccctc
    20521 atgggcgggt cttggtgagg cggagactgg gcgttatttt gaggcggtct gccttgagat
    20581 aaaggccttc gcggctgagc agggaagagt gcccgcgggc acggtttatt ttggcggggg
    20641 cacgccctct tatgtggcag ccgattatat cggacgggtc atggactgta tccgggagtg
    20701 ctttgagctg cctgaagagg ccattgaggc gaccattgag gcgaaccccg gaaccctgac
    20761 cgatgcgaaa tgccgggctt accgaaacat gggccttaac cgtgtgagta tgggcctcca
    20821 gaccacaagc gacagggggc tgaaggctct gggccgtatc cacacctacg cggattttaa
    20881 gacgtctctg gatctgctgg gaagcgcggg atttgagaat atctcagcgg atttgatgtt
    20941 tggcctgccg gggcagaccc tggaggatgt acggcaggat attgaccgtc tcactgccct
    21001 tgcttccatt aagcatattt cctgctacag tctgaaaatc gaggagggaa cagcctttga
    21061 cacgctgtac cgccagggga aactgctgct gccggacgag gcgctggaaa ggcagatgca
    21121 gcacactatc attgacggtc tggctgagaa cggctttgag cagtatgaga tatcgaactt
    21181 tgcgaggaaa ggctgggaaa gccgtcacaa cagcctgtac tgggtgatga agccctatgt
    21241 gggctttgga ctgggggcag cctcctatta taaggaagag cgccgaacca atgtgatgga
    21301 tatggaagac tactgcgctc tggtcacgca gggaaaagcc ccggtgctcg agacgcacat
    21361 tttggacgcc caggagaaaa agggcgactt tatgttcctg ggactgcggc gcatgtgcgg
    21421 ggtggatgat gcggattacc gggagctgtt tggcagtagt ttttttgagg attttgagga
    21481 aatcgaaaac cttgtgaagg cgggacttct cacgcgtgag gatcaggtta tccggcttac
    21541 cccaaagggg caggacctgg cgaatcaggt gtttgtagct tttgtttagg acgggtctgc
    21601 tgcggtggaa tacgctgtgg acggtcttgc ttaaataatg tttaaatctt aaaaacttga
    21661 catttatctt atagaaatct attgacaaag taagaccccg gtggtatatt atagtcaaga
    21721 tattagcact cacatgtaac gagtgctaat aaagaggtga ataaaatgga cttgaaagag
    21781 agaaagaaga agatattgga ggtaatcatt aaggattaca tcaataccgc cgaaccggta
    21841 gggtcccgga ccttgtcaaa gcgttataac cttggcatca gccctgcgac catccggaac
    21901 gaaatggctg atctcgaaga cctgggcttt ttaatgcagc cgcacacctc atctggaaga
    21961 attccgactc agctggcata ccgctattat gtcgatgaga tcatgcaaat ccaaaaatta
    22021 gctaaggttg tgagaaatga catccataat gggtatctaa aaataacaag ggagctggat
    22081 aacaccatga accacacggc aaaggtgctg tcccagctga ccaactacac ctctgtggtg
    22141 ctgtcgccgc gggtttcctg ctttaactgc aagcacgtac agattgttcc tttaataaag
    22201 gaacgtgttt tactcattgt ggtcacctat gaagggatgg caaagaacat tgaaatgacc
    22261 ctttcgcagg aaattgacac cactttggcc ctgaaactga gtaatgtctt aaacagtttc
    22321 ctcaaaaata tttccttcca ggaaattaac atggagctag tcgatcagat tcaggaattg
    22381 tctccggatg aaagcaattt actccgggaa attcttccgg tattaaggga tactttgatg
    22441 gaagaggctt cagacatcca ttccatgggt ctgacgaatc ttttcaatta tcctgaattc
    22501 agtgatgtgg aaaaaatccg tcacctggtc aatgtgatcg aggagaaacc gctgctggcg
    22561 ggtattctgt caagtgatga caccagtcag gtgattaaca tcagcatcgg ggatgaaaat
    22621 gataatgaga acctgaagga attcagtatt attacaacaa cctacgagct ggaaggaaag
    22681 accgtaggcg cttttggggt cataggacca acgaggatga attatgataa tgtttcctcg
    22741 gttcttgatt atataagaaa tgaactgaac acaaacttaa caaaattatt aatgaaatag
    22801 gtggttaaat ggctaaggaa gaaaagatgg aacaaaacgt agacgaaacc gttaaggaag
    22861 aagctacaga ggaacagaca acagaagaac agacagctga ggaagctgta gaggatgttg
    22921 aaaaatcggt aaatgaagcg gccaaggcag aggaagcagc gatggagcgt cttatgcgcc
    22981 ttcaggcgga ttttgaaaac tataaaaaaa gaacgcagaa ggaaaagacc gacatttacc
    23041 agtttgctct tgaaggcttt gtcacaaagc ttttaccagt gcttgacaac ctggaccgcg
    23101 ccgaagcggc agccgatgat gacaatacgg acaaataccg cgagggtgtt cagatggttt
    23161 tcaagcagtt aattggtgtt ctgaacgagg agggtctgca ggaaattgac tgtgtgggca
    23221 ccgcctttga tccgaacttc caccacggtg ttgccgttgg agaagatcct gaaaaagatg
    23281 atcaggttgt tctggaggtt ttccagaagg gctacacttt taaggacaag gtcataagac
    23341 ccgcaatggt taaggttaat cagaagtaaa aaaacgcatg gcgtcggcgt tttggaaacg
    23401 acgcaaagtc cggccatccg gtcggcaatt aaatctggaa aacaaacttt cgaatcaata
    23461 ggaggacata tattatgggt aaagaaaaaa ttattggtat tgacttaggt actacaaact
    23521 cttgcgtagc tgttttggaa ggtggcgaac cggttgttat cccaaatgca gaagggaacc
    23581 gtacaacgcc gtccgttgtc gcattcacta aagacggtga aagactggtc ggccaggtgg
    23641 ctaaacgtca ggctgtcacc aatccggacc gtacagttgc ttccatcaag agacacatgg
    23701 ggaccgacta taaggtaacc atcgacgata agagctatac accgcaggaa atctctgcaa
    23761 tgatcctgca gaaattaaaa tcagacgcag aagcttacct tggcgaaaca gttaccaaag
    23821 ctgttatcac tgtacctgca tacttcagcg atgctcagag acaggcaacc aaggacgccg
    23881 gtaaaattgc cggtttagat gtactgcgta tcatcaacga accaaccgct gcttcactgg
    23941 cttatggtct tgacaaggca gacaatcaga aaattatggt ttatgacctt ggcggcggta
    24001 ccttcgacgt atccatcctg gaattaggcg acggcgtttt tgaagttaag gcgaccaacg
    24061 gtaacaacaa cctgggcggc gacgactttg acaacaaggt cattgactgg atggctgaag
    24121 aattcaaaaa atcccacggc atcgacctga aatctgataa aatggcgtta cagcgtttga
    24181 aagaagctgc tgaaaaagct aaaattgaac tctccagcgt tatgaaatcg gacattaacc
    24241 tgccatttat cactgcaacc gcagaaggac cgcagcatct ggaactctcc ctgacaagag
    24301 cgaaattcga cgaattaacc tctggtcttg taagagaaac cgaaggacct gtctcaaaag
    24361 cgatgagcga cgcaggcctt ggcaaaaacg aactgaacaa ggtgatcctg gttggtggtt
    24421 ccacaagaat cccagcagta caggatgctg ttaagaactt aac
//
