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Overview
1.1
1.2
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1.7
1.8

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP019962.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1 | cyclic-lactone-autoinducer | 471,283 | 487,313 |
Region 2 | RiPP-like | 1,056,978 | 1,067,349 |
Region 3 | ranthipeptide | 1,770,436 | 1,792,015 |
Region 4 | cyclic-lactone-autoinducer | 1,848,879 | 1,873,341 |
Region 5 | RRE-containing | 2,748,090 | 2,767,916 |
Region 6 | terpene | 2,790,727 | 2,811,590 |
Region 7 | RRE-containing | 3,421,822 | 3,442,247 |
Region 8 | RiPP-like | 4,204,901 | 4,215,710 |

NZ_CP019962.1 - Region 1 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 471,283 - 487,313 nt. (total: 16,031 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000488.1 |  | 0.24 | RiPP | circularin A | Clostridium beijerinckii
BGC0000553.1 |  | 0.17 | RiPP | SRO15-2212 | Streptomyces filamentosus NRRL 15998
BGC0000496.1 |  | 0.17 | RiPP | AmfS | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000554.1 |  | 0.16 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000487.1 |  | 0.16 | RiPP | carnocyclin | Carnobacterium maltaromaticum
BGC0000519.1 |  | 0.16 | RiPP | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis
BGC0000571.1 |  | 0.16 | RiPP | burhizin | Paraburkholderia rhizoxinica HKI 454
BGC0000617.1 |  | 0.16 | RiPP | coagulin | Bacillus coagulans
BGC0001498.1 |  | 0.16 | Other | aerobactin | Xenorhabdus szentirmaii DSM 16338
BGC0001210.1 |  | 0.16 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000488.1 |  | 0.58 | RiPP | circularin A | Clostridium beijerinckii
BGC0000553.1 |  | 0.48 | RiPP | SRO15-2212 | Streptomyces filamentosus NRRL 15998
BGC0000496.1 |  | 0.48 | RiPP | AmfS | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000554.1 |  | 0.47 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000487.1 |  | 0.47 | RiPP | carnocyclin | Carnobacterium maltaromaticum
BGC0000519.1 |  | 0.47 | RiPP | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis
BGC0000571.1 |  | 0.47 | RiPP | burhizin | Paraburkholderia rhizoxinica HKI 454
BGC0000617.1 |  | 0.47 | RiPP | coagulin | Bacillus coagulans
BGC0001498.1 |  | 0.47 | Other | aerobactin | Xenorhabdus szentirmaii DSM 16338
BGC0001210.1 |  | 0.46 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP019962.1 - Region 2 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,056,978 - 1,067,349 nt. (total: 10,372 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

No matches found.

No matches found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP019962.1 - Region 3 - ranthipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,770,436 - 1,792,015 nt. (total: 21,580 nt) Show pHMM detection rules used
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ranthipeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001314.1 |  | 0.19 | Terpene | tirucalla | Arabidopsis thaliana
BGC0000599.1 |  | 0.13 | RiPP | thuricin CD α, thuricin CD β | Bacillus thuringiensis
BGC0001887.1 |  | 0.13 | RiPP | huazacin | Bacillus thuringiensis serovar huazhongensis BGSC 4BD1
BGC0001077.1 |  | 0.09 | Terpene, Polyketide | alkyl-O-dihydrogeranyl-methoxyhydroquinones | Actinoplanes missouriensis 431

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001314.1 |  | 0.51 | Terpene | tirucalla | Arabidopsis thaliana
BGC0000599.1 |  | 0.42 | RiPP | thuricin CD α, thuricin CD β | Bacillus thuringiensis
BGC0001887.1 |  | 0.42 | RiPP | huazacin | Bacillus thuringiensis serovar huazhongensis BGSC 4BD1
BGC0001077.1 |  | 0.34 | Terpene, Polyketide | alkyl-O-dihydrogeranyl-methoxyhydroquinones | Actinoplanes missouriensis 431

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP019962.1 - Region 4 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,848,879 - 1,873,341 nt. (total: 24,463 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000599.1 |  | 0.15 | RiPP | thuricin CD α, thuricin CD β | Bacillus thuringiensis
BGC0001887.1 |  | 0.14 | RiPP | huazacin | Bacillus thuringiensis serovar huazhongensis BGSC 4BD1
BGC0001638.1 |  | 0.14 | RiPP | klebsazolicin | Klebsiella pneumoniae subsp. ozaenae
BGC0001391.1 |  | 0.13 | RiPP | thusin | Bacillus thuringiensis serovar rongseni
BGC0001311.1 |  | 0.13 | RiPP | flavecins | Ruminococcus flavefaciens FD-1
BGC0000569.1 |  | 0.13 | RiPP | plantazolicin | Bacillus velezensis FZB42
BGC0000626.1 |  | 0.13 | RiPP | thuricin | Bacillus thuringiensis
BGC0001607.1 |  | 0.13 | Other | gilvusmycin | Streptomyces sp. NRRL B-1347
BGC0000541.1 |  | 0.13 | RiPP | paenicidin A | Paenibacillus polymyxa
BGC0001173.1 |  | 0.13 | RiPP | plantazolicin | Bacillus pumilus ATCC 7061

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000599.1 |  | 0.44 | RiPP | thuricin CD α, thuricin CD β | Bacillus thuringiensis
BGC0001887.1 |  | 0.44 | RiPP | huazacin | Bacillus thuringiensis serovar huazhongensis BGSC 4BD1
BGC0001638.1 |  | 0.43 | RiPP | klebsazolicin | Klebsiella pneumoniae subsp. ozaenae
BGC0001391.1 |  | 0.42 | RiPP | thusin | Bacillus thuringiensis serovar rongseni
BGC0001311.1 |  | 0.42 | RiPP | flavecins | Ruminococcus flavefaciens FD-1
BGC0000569.1 |  | 0.42 | RiPP | plantazolicin | Bacillus velezensis FZB42
BGC0000626.1 |  | 0.41 | RiPP | thuricin | Bacillus thuringiensis
BGC0001607.1 |  | 0.41 | Other | gilvusmycin | Streptomyces sp. NRRL B-1347
BGC0000541.1 |  | 0.41 | RiPP | paenicidin A | Paenibacillus polymyxa
BGC0001173.1 |  | 0.41 | RiPP | plantazolicin | Bacillus pumilus ATCC 7061

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP019962.1 - Region 5 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,748,090 - 2,767,916 nt. (total: 19,827 nt) Show pHMM detection rules used
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001551.1 |  | 0.17 | RiPP | citrulassin E | Streptomyces glaucescens
BGC0000554.1 |  | 0.15 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001634.1 |  | 0.15 | RiPP | keywimysin | Streptomyces sp. NRRL F-5702
BGC0000768.1 |  | 0.15 | Saccharide | gellan polysaccharide | Sphingomonas elodea ATCC 31461
BGC0000797.1 |  | 0.15 | Saccharide | sphingan polysaccharide | Sphingomonas sp. S88
BGC0001928.1 |  | 0.15 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0000584.1 |  | 0.15 | RiPP | colicin V | Escherichia coli
BGC0000587.1 |  | 0.14 | RiPP | microcin H47 | Escherichia coli
BGC0001779.1 |  | 0.14 | RiPP | siamycin | Streptomyces nodosus
BGC0000294.1 |  | 0.14 | NRP | acinetobactin | Acinetobacter baumannii

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001551.1 |  | 0.49 | RiPP | citrulassin E | Streptomyces glaucescens
BGC0000554.1 |  | 0.46 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001634.1 |  | 0.46 | RiPP | keywimysin | Streptomyces sp. NRRL F-5702
BGC0000768.1 |  | 0.45 | Saccharide | gellan polysaccharide | Sphingomonas elodea ATCC 31461
BGC0000797.1 |  | 0.45 | Saccharide | sphingan polysaccharide | Sphingomonas sp. S88
BGC0001928.1 |  | 0.45 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0000584.1 |  | 0.45 | RiPP | colicin V | Escherichia coli
BGC0000587.1 |  | 0.44 | RiPP | microcin H47 | Escherichia coli
BGC0001779.1 |  | 0.43 | RiPP | siamycin | Streptomyces nodosus
BGC0000294.1 |  | 0.43 | NRP | acinetobactin | Acinetobacter baumannii

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
NZ_CP019962.1 - Region 6 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,790,727 - 2,811,590 nt. (total: 20,864 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.45 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000648.1 |  | 0.23 | Terpene | carotenoid | Myxococcus xanthus
BGC0000656.1 |  | 0.23 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000646.1 |  | 0.21 | Terpene | β-carotein | uncultured bacterium
BGC0001227.1 |  | 0.21 | Terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0000633.1 |  | 0.21 | Terpene | carotenoid | Streptomyces avermitilis
BGC0000664.1 |  | 0.21 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000640.1 |  | 0.20 | Terpene | carotenoid | Enterobacteriaceae bacterium DC404
BGC0001456.1 |  | 0.19 | Terpene | isorenieratene | Streptomyces argillaceus
BGC0000642.1 |  | 0.18 | Terpene | carotenoid | Enterobacteriaceae bacterium DC413

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.75 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000648.1 |  | 0.56 | Terpene | carotenoid | Myxococcus xanthus
BGC0000656.1 |  | 0.56 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000646.1 |  | 0.54 | Terpene | β-carotein | uncultured bacterium
BGC0001227.1 |  | 0.54 | Terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0000633.1 |  | 0.53 | Terpene | carotenoid | Streptomyces avermitilis
BGC0000664.1 |  | 0.53 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000640.1 |  | 0.53 | Terpene | carotenoid | Enterobacteriaceae bacterium DC404
BGC0001456.1 |  | 0.52 | Terpene | isorenieratene | Streptomyces argillaceus
BGC0000642.1 |  | 0.50 | Terpene | carotenoid | Enterobacteriaceae bacterium DC413

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP019962.1 - Region 7 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,421,822 - 3,442,247 nt. (total: 20,426 nt) Show pHMM detection rules used
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000877.1 |  | 0.08 | Other | polyoxin A, polyoxin H | Streptomyces cacaoi subsp. asoensis
BGC0001538.1 |  | 0.07 | NRP, Polyketide | caboxamycin | Streptomyces sp. NTK 937
BGC0001079.1 |  | 0.06 | Polyketide, Terpene | napyradiomycin A80915C | Streptomyces aculeolatus
BGC0000224.1 |  | 0.05 | Polyketide | fredericamycin A | Streptomyces griseus
BGC0000267.1 |  | 0.04 | Polyketide, Saccharide | saquayamycin Z | Micromonospora sp. Tu 6368
BGC0000079.1 |  | 0.04 | Polyketide | X-14547 | Streptomyces antibioticus
BGC0001193.1 |  | 0.04 | NRP | thiolutin | Saccharothrix algeriensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000877.1 |  | 0.31 | Other | polyoxin A, polyoxin H | Streptomyces cacaoi subsp. asoensis
BGC0001538.1 |  | 0.28 | NRP, Polyketide | caboxamycin | Streptomyces sp. NTK 937
BGC0001079.1 |  | 0.25 | Polyketide, Terpene | napyradiomycin A80915C | Streptomyces aculeolatus
BGC0000224.1 |  | 0.23 | Polyketide | fredericamycin A | Streptomyces griseus
BGC0000267.1 |  | 0.20 | Polyketide, Saccharide | saquayamycin Z | Micromonospora sp. Tu 6368
BGC0000079.1 |  | 0.19 | Polyketide | X-14547 | Streptomyces antibioticus
BGC0001193.1 |  | 0.19 | NRP | thiolutin | Saccharothrix algeriensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP019962.1 - Region 8 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 4,204,901 - 4,215,710 nt. (total: 10,810 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000294.1 |  | 0.17 | NRP | acinetobactin | Acinetobacter baumannii
BGC0000500.1 |  | 0.16 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0001928.1 |  | 0.16 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0000554.1 |  | 0.15 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001862.1 |  | 0.15 | RiPP | geocillicin | Aeribacillus pallidus
BGC0001930.1 |  | 0.15 | RiPP | pallidocin | Aeribacillus pallidus
BGC0001861.1 |  | 0.15 | RiPP | bacillicin BAG2O | Bacillus cereus BAG2O-1
BGC0000584.1 |  | 0.15 | RiPP | colicin V | Escherichia coli
BGC0001120.1 |  | 0.14 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000802.1 |  | 0.14 | Saccharide | succinoglycan | Sinorhizobium meliloti

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000294.1 |  | 0.48 | NRP | acinetobactin | Acinetobacter baumannii
BGC0000500.1 |  | 0.46 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0001928.1 |  | 0.46 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0000554.1 |  | 0.46 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001862.1 |  | 0.46 | RiPP | geocillicin | Aeribacillus pallidus
BGC0001930.1 |  | 0.46 | RiPP | pallidocin | Aeribacillus pallidus
BGC0001861.1 |  | 0.45 | RiPP | bacillicin BAG2O | Bacillus cereus BAG2O-1
BGC0000584.1 |  | 0.44 | RiPP | colicin V | Escherichia coli
BGC0001120.1 |  | 0.44 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000802.1 |  | 0.44 | Saccharide | succinoglycan | Sinorhizobium meliloti

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names