LOCUS       c00001_NZ_QRYH..       21629 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_QRYH01000001.1 Holdemanella biformis strain AF15-5 AF15-5.Scaf1,
            whole genome shotgun sequence.
ACCESSION   NZ_QRYH01000001
VERSION     NZ_QRYH01000001
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:10:45
            Original ID  :: NZ_QRYH01000001.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 122874
            Orig. end    :: 144503
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21629
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[132874:134503]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11629
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21629
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21629
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /tool="antismash"
     PFAM_domain     1245..1496
                     /aSDomain="MscL"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01741.20"
                     /description="Large-conductance mechanosensitive channel,
                     MscL"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_110_0001"
                     /evalue="2.40E-17"
                     /label="ctg1_110"
                     /locus_tag="ctg1_110"
                     /protein_end="84"
                     /protein_start="0"
                     /score="63.5"
                     /tool="antismash"
                     /translation="MPIVGILIGGLDFTGLKIQVGTVAITYGNFIQNVVDFLIVAACIF
                     TMLKFLAHFKKTTNDQLDQKESKQDDTVVLLEEIRDLLK"
     CDS             1245..1517
                     /locus_tag="ctg1_110"
                     /transl_table=11
                     /translation="MPIVGILIGGLDFTGLKIQVGTVAITYGNFIQNVVDFLIVAACIF
                     TMLKFLAHFKKTTNDQLDQKESKQDDTVVLLEEIRDLLKKIDKVN"
     CDS             complement(1491..2387)
                     /locus_tag="ctg1_111"
                     /transl_table=11
                     /translation="MNIILLVLGFILLLKGADWFVDGASSIASRFGIPQLIIGLTIVAM
                     GTSLPEAFVSITAALKSNAAITIGNVVGSNILNVGIILGITALIRPLHIQNSTMKYEMP
                     FMILVTFVLILLGINTTISRLDGIIMWLFFLGYLYYIFKMSKNQMEETEIKQTNPLFIP
                     LGLVCLMIGSNFAVDAATNIAISFGVSQRFIGLTIVALGTSLPELVTSVTAAKKGNADI
                     AIGNIIGSNIFNILFVVGSSALITPVPFEPHFIIDSFVAILIGLVLYLCTKKTRVLDKK
                     AGILLLITYLIYFIYLL"
     PFAM_domain     complement(1497..1904)
                     /aSDomain="Na_Ca_ex"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01699.26"
                     /description="Sodium/calcium exchanger protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_111_0003"
                     /evalue="1.90E-30"
                     /label="ctg1_111"
                     /locus_tag="ctg1_111"
                     /protein_end="297"
                     /protein_start="161"
                     /score="105.9"
                     /tool="antismash"
                     /translation="IPLGLVCLMIGSNFAVDAATNIAISFGVSQRFIGLTIVALGTSLP
                     ELVTSVTAAKKGNADIAIGNIIGSNIFNILFVVGSSALITPVPFEPHFIIDSFVAILIG
                     LVLYLCTKKTRVLDKKAGILLLITYLIYFIYL"
     aSDomain        complement(1509..2384)
                     /aSDomain="TIGR00367"
                     /aSTool="tigrfam"
                     /description="TIGR00367: K+-dependent Na+/Ca+ exchanger
                     homolog"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_111_0001"
                     /evalue="4.10E-76"
                     /identifier="TIGR00367"
                     /label="ctg1_111"
                     /locus_tag="ctg1_111"
                     /protein_end="293"
                     /protein_start="1"
                     /score="254.0"
                     /tool="antismash"
                     /translation="NIILLVLGFILLLKGADWFVDGASSIASRFGIPQLIIGLTIVAMG
                     TSLPEAFVSITAALKSNAAITIGNVVGSNILNVGIILGITALIRPLHIQNSTMKYEMPF
                     MILVTFVLILLGINTTISRLDGIIMWLFFLGYLYYIFKMSKNQMEETEIKQTNPLFIPL
                     GLVCLMIGSNFAVDAATNIAISFGVSQRFIGLTIVALGTSLPELVTSVTAAKKGNADIA
                     IGNIIGSNIFNILFVVGSSALITPVPFEPHFIIDSFVAILIGLVLYLCTKKTRVLDKKA
                     GILLLITYLIY"
     PFAM_domain     complement(1962..2381)
                     /aSDomain="Na_Ca_ex"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01699.26"
                     /description="Sodium/calcium exchanger protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_111_0002"
                     /evalue="1.80E-31"
                     /label="ctg1_111"
                     /locus_tag="ctg1_111"
                     /protein_end="142"
                     /protein_start="2"
                     /score="109.2"
                     /tool="antismash"
                     /translation="IILLVLGFILLLKGADWFVDGASSIASRFGIPQLIIGLTIVAMGT
                     SLPEAFVSITAALKSNAAITIGNVVGSNILNVGIILGITALIRPLHIQNSTMKYEMPFM
                     ILVTFVLILLGINTTISRLDGIIMWLFFLGYLYYIF"
     CDS             2649..3566
                     /locus_tag="ctg1_112"
                     /transl_table=11
                     /translation="VNKIKDKTMKEFLENNAYFVDFFNAYFFDGERVLKPENCMELDSE
                     MNDSNMDIEKHVDVIRKYNDGNLYSAFVIENQSCVDMSMVVRAAAYEFVAYDRMLKKLK
                     KNKAKEKLPMVHILVFYTGERPWNAANKLSQLVDVDERFESYFHDYQMNLIEITGNTSY
                     NFNEEDVHNLFYICRSIYDQSIYEGKSNSFGFVKSSVLKVVKTLTDVEWLDLEELEEKE
                     EIEMCEAEKRWLEVKSKEWEAKGIKKGIEQGIEQGIEQGIEQGSEKKELEMYRKMMDKG
                     FGIKAIASIFSVSEESIEKLLMKA"
     PFAM_domain     2664..3203
                     /aSDomain="Transposase_31"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04754.14"
                     /description="Putative transposase, YhgA-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_112_0004"
                     /evalue="2.00E-14"
                     /label="ctg1_112"
                     /locus_tag="ctg1_112"
                     /protein_end="185"
                     /protein_start="5"
                     /score="53.8"
                     /tool="antismash"
                     /translation="DKTMKEFLENNAYFVDFFNAYFFDGERVLKPENCMELDSEMNDSN
                     MDIEKHVDVIRKYNDGNLYSAFVIENQSCVDMSMVVRAAAYEFVAYDRMLKKLKKNKAK
                     EKLPMVHILVFYTGERPWNAANKLSQLVDVDERFESYFHDYQMNLIEITGNTSYNFNEE
                     DVHNLFYICRSIYDQSI"
     CDS             3710..4627
                     /locus_tag="ctg1_113"
                     /transl_table=11
                     /translation="MVFLLLVLGMVLLMKGADLFVDGSASVARKLKVPSVIIGLTIVAL
                     GTSLPEASVSITAGLMGSNEIAISNIVGSNIFNTLVVVGTSAVITPFLMDQDILNRDLK
                     INILVSILLSIFVLNGMLNRFEGIIFLVGLVLFILNLIRSAKKNRVEDEKVETLSGIKC
                     LIYIVIGVACIIWGGDITVDSAKQIAAMLGMSDTLIGLTVVSIGTSLPELVTSVVAARK
                     GESGLSLGNAIGSNIMNILFILGASSTIHPIAATSQNIIDTFVLIGVSLLIYGIAKKGD
                     TMTRKKGIFMILVYVIYMIYIIVR"
     PFAM_domain     3713..4129
                     /aSDomain="Na_Ca_ex"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01699.26"
                     /description="Sodium/calcium exchanger protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_113_0005"
                     /evalue="2.30E-26"
                     /label="ctg1_113"
                     /locus_tag="ctg1_113"
                     /protein_end="140"
                     /protein_start="1"
                     /score="92.6"
                     /tool="antismash"
                     /translation="VFLLLVLGMVLLMKGADLFVDGSASVARKLKVPSVIIGLTIVALG
                     TSLPEASVSITAGLMGSNEIAISNIVGSNIFNTLVVVGTSAVITPFLMDQDILNRDLKI
                     NILVSILLSIFVLNGMLNRFEGIIFLVGLVLFILN"
     aSDomain        3713..4603
                     /aSDomain="TIGR00367"
                     /aSTool="tigrfam"
                     /description="TIGR00367: K+-dependent Na+/Ca+ exchanger
                     homolog"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_113_0002"
                     /evalue="2.80E-73"
                     /identifier="TIGR00367"
                     /label="ctg1_113"
                     /locus_tag="ctg1_113"
                     /protein_end="298"
                     /protein_start="1"
                     /score="244.7"
                     /tool="antismash"
                     /translation="VFLLLVLGMVLLMKGADLFVDGSASVARKLKVPSVIIGLTIVALG
                     TSLPEASVSITAGLMGSNEIAISNIVGSNIFNTLVVVGTSAVITPFLMDQDILNRDLKI
                     NILVSILLSIFVLNGMLNRFEGIIFLVGLVLFILNLIRSAKKNRVEDEKVETLSGIKCL
                     IYIVIGVACIIWGGDITVDSAKQIAAMLGMSDTLIGLTVVSIGTSLPELVTSVVAARKG
                     ESGLSLGNAIGSNIMNILFILGASSTIHPIAATSQNIIDTFVLIGVSLLIYGIAKKGDT
                     MTRKKGIFMILVYVIY"
     PFAM_domain     4199..4618
                     /aSDomain="Na_Ca_ex"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01699.26"
                     /description="Sodium/calcium exchanger protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_113_0006"
                     /evalue="1.10E-27"
                     /label="ctg1_113"
                     /locus_tag="ctg1_113"
                     /protein_end="303"
                     /protein_start="163"
                     /score="96.9"
                     /tool="antismash"
                     /translation="LIYIVIGVACIIWGGDITVDSAKQIAAMLGMSDTLIGLTVVSIGT
                     SLPELVTSVVAARKGESGLSLGNAIGSNIMNILFILGASSTIHPIAATSQNIIDTFVLI
                     GVSLLIYGIAKKGDTMTRKKGIFMILVYVIYMIYII"
     CDS             complement(4635..5243)
                     /locus_tag="ctg1_114"
                     /transl_table=11
                     /translation="MKSKIIENKKIKENNLLQAAFNLFTKEDITNVSVNDIVKSAGVAK
                     GTFYLYFKDKYQIRDILIQKEAHRLFEEAHKQLEKNDIRNFEDSVIFLINQVLIRLENN
                     PLILKFVERNLSWGVFHAQLNTAIDNDSFNLIKEFNEIATANGYEFENSEVILYLIVEL
                     TGSTCYNSILHSQPLPIEEYKPILFDSIRAILSQGKKKS"
     PFAM_domain     complement(5070..5198)
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00440.25"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_114_0007"
                     /evalue="9.80E-13"
                     /label="ctg1_114"
                     /locus_tag="ctg1_114"
                     /protein_end="58"
                     /protein_start="15"
                     /score="47.8"
                     /tool="antismash"
                     /translation="LLQAAFNLFTKEDITNVSVNDIVKSAGVAKGTFYLYFKDKYQI"
     CDS             5430..7511
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:MMPL domain-containing transport protein (Score:
                     134; E-value: 8.6e-41)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_115"
                     /transl_table=11
                     /translation="MDKMSKWIVKYRNLILAVAIILLIPSAIGYFNTNINYDLLSYLPS
                     TSESMKTQKILGDDFNLSSVDFLVVNNKSDQEAAKIKEEINKIDGVEKCIWRDDVLDIS
                     VPKQAIPESIQDMLYSGNSTMMIVTFKEPTSSMRTMNAISKIKKYTKDDCYLGGMSAIS
                     EDTKDQTEHDTPIYAGIAVVLCMVVLFLGLESTIAPVVFMLGMIFPIVYNFGTNVFLGE
                     ISYITKALAVVLQLAVTLDYSIFLLHRYQEEKQKLPNEEAMAKAIKATFTSITSSSITT
                     IAGFVALCVMQLTLGRDIGIVMAKGVVLGVLSTIFILPSLLMFFDKTIEKYKHKTILNE
                     LHRVPRFVIHHYKKILVAFVLIFIPFGYGQSHTNIYYDLISGMPGDFASIIGTNQLKDK
                     FDMTTTHFVLVDDKLTTNEIQNMCSEIKDLKGIHNVLAYEEFVGPGLASNFTPSVVKDI
                     FQNGGKKLIVVNSDYKAATNELNTQLDKMDTIIHKYDKKGMIGGEGSMTRDLITTTNTD
                     FAMVNVLSVIMIFIIVALTFKSFALPVILVLTIEFAITINMGIPFFTKTTLPFIASMVI
                     GTIQLGATVDYAILMTTRFKEELSHGKKVKEAALIAMEKSSVSIMTSGFSFFAACIGVS
                     FVAKMDLIKSLVILLARGALISVVSILLVLPSLLIFCHKFIEKTTKDWPESNMEAKGE"
     PFAM_domain     5553..6413
                     /aSDomain="MMPL"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03176.17"
                     /description="MMPL family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_115_0008"
                     /evalue="1.00E-30"
                     /label="ctg1_115"
                     /locus_tag="ctg1_115"
                     /protein_end="328"
                     /protein_start="41"
                     /score="107.0"
                     /tool="antismash"
                     /translation="YLPSTSESMKTQKILGDDFNLSSVDFLVVNNKSDQEAAKIKEEIN
                     KIDGVEKCIWRDDVLDISVPKQAIPESIQDMLYSGNSTMMIVTFKEPTSSMRTMNAISK
                     IKKYTKDDCYLGGMSAISEDTKDQTEHDTPIYAGIAVVLCMVVLFLGLESTIAPVVFML
                     GMIFPIVYNFGTNVFLGEISYITKALAVVLQLAVTLDYSIFLLHRYQEEKQKLPNEEAM
                     AKAIKATFTSITSSSITTIAGFVALCVMQLTLGRDIGIVMAKGVVLGVLSTIFILPSLL
                     MFFDKT"
     PFAM_domain     6807..7454
                     /aSDomain="MMPL"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03176.17"
                     /description="MMPL family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_115_0009"
                     /evalue="2.00E-26"
                     /label="ctg1_115"
                     /locus_tag="ctg1_115"
                     /protein_end="675"
                     /protein_start="459"
                     /score="92.8"
                     /tool="antismash"
                     /translation="QNGGKKLIVVNSDYKAATNELNTQLDKMDTIIHKYDKKGMIGGEG
                     SMTRDLITTTNTDFAMVNVLSVIMIFIIVALTFKSFALPVILVLTIEFAITINMGIPFF
                     TKTTLPFIASMVIGTIQLGATVDYAILMTTRFKEELSHGKKVKEAALIAMEKSSVSIMT
                     SGFSFFAACIGVSFVAKMDLIKSLVILLARGALISVVSILLVLPSLLIFCHKF"
     CDS             7514..9907
                     /locus_tag="ctg1_116"
                     /transl_table=11
                     /translation="MNLSHTVKVVGSVVLSAVMAGSMMPVTVFAQNNDENPTEKTETVY
                     SVLNSDGSISDTIVSSWLHDEDGINNIKETLNLTDVKNIKSNEKPSKNGNTYTWNAKGN
                     DVYYEGTATKQLPVSVKLRYELDGQEMSAKDMEGKSGHLKLTISFTNNYSEVKNINGKS
                     IVIHPSYLAGGMLNMSTGNFTNVKCESGKIVNDGTNEMLAFANIPGLNETLRSAGLDKV
                     NNQLGISDDVTVEADVNNFDLGSIMVGMTNEIDLASELGEIGSVSELTDGIDQLMDADD
                     QLIDGSKQLYDGTTQLKEGIAPLSSAYPQIETLTNAFDQLHDGTTTLSTGLNQYTAGVD
                     QLNVVSKQNLYKLSMGATTLNTSLNNKESKSQLNQLVQGSQALDAGIQNLNEQVNGDDS
                     MLKPDMVKNLTEALKTTNEQVGKLGQVLNDLQDQEGAFVDLSNQITKASENINKLGTLQ
                     TSFKEVTDGASAIITADNEQIKSVDDQLAAIRTKEINALNASIEALKNAANAVPEDDTT
                     GAKAKIEEQINALESQKATLGDASSLSVTLKDLSQCQAGIDKIVADSKETLEELNAVYN
                     SSKTDIKNLSTKLDEAKKSIEVLNGVMKQLNENGITSEEFEKKVNTLKAGVEKLAKNSP
                     ALANGVATLANKLNNLGEGLNGLDSGMSQAYTGITQATSQLSDNSDSLRNGAKALNDGT
                     AQLSASKSKMSELTSGLTKLSDAVDQLNDGAQQLYEGNEQFKSEGLDQLKEKVDLGVGE
                     LETLQSVMNEIKAMNKEYASYSGAPEGATVTSRYVFRTKEESSK"
     aSDomain        8309..8392
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_116_0003"
                     /evalue="5.70E-05"
                     /identifier="TIGR03057"
                     /label="ctg1_116"
                     /locus_tag="ctg1_116"
                     /protein_end="293"
                     /protein_start="265"
                     /score="21.2"
                     /tool="antismash"
                     /translation="VSELTDGIDQLMDADDQLIDGSKQLYDG"
     aSDomain        8471..8542
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_116_0004"
                     /evalue="6.70E-06"
                     /identifier="TIGR03057"
                     /label="ctg1_116"
                     /locus_tag="ctg1_116"
                     /protein_end="343"
                     /protein_start="319"
                     /score="24.1"
                     /tool="antismash"
                     /translation="QLHDGTTTLSTGLNQYTAGVDQLN"
     aSDomain        9371..9451
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_116_0005"
                     /evalue="1.50E-04"
                     /identifier="TIGR03057"
                     /label="ctg1_116"
                     /locus_tag="ctg1_116"
                     /protein_end="646"
                     /protein_start="619"
                     /score="19.8"
                     /tool="antismash"
                     /translation="VNTLKAGVEKLAKNSPALANGVATLAN"
     aSDomain        9626..9706
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_116_0006"
                     /evalue="8.80E-07"
                     /identifier="TIGR03057"
                     /label="ctg1_116"
                     /locus_tag="ctg1_116"
                     /protein_end="731"
                     /protein_start="704"
                     /score="26.9"
                     /tool="antismash"
                     /translation="SELTSGLTKLSDAVDQLNDGAQQLYEG"
     CDS             10001..10153
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_117"
                     /sec_met_domain="TIGR03973 (E-value: 6.7e-25, bitscore:
                     80.5, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 1.5e-24, bitscore: 79.5,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHINTVDTRNLCESAKNGGCGECQTSCQSACKTSCGIANQACEH
                     NKESK"
     aSDomain        10004..10132
                     /aSDomain="TIGR03973"
                     /aSTool="tigrfam"
                     /description="six_Cys_in_45: six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_117_0007"
                     /evalue="1.40E-23"
                     /identifier="TIGR03973"
                     /label="ctg1_117"
                     /locus_tag="ctg1_117"
                     /protein_end="44"
                     /protein_start="1"
                     /score="80.5"
                     /tool="antismash"
                     /translation="KHINTVDTRNLCESAKNGGCGECQTSCQSACKTSCGIANQACE"
     PFAM_domain     10004..10132
                     /aSDomain="SCIFF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13165.8"
                     /description="Six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_117_0010"
                     /evalue="1.20E-22"
                     /label="ctg1_117"
                     /locus_tag="ctg1_117"
                     /protein_end="44"
                     /protein_start="1"
                     /score="79.6"
                     /tool="antismash"
                     /translation="KHINTVDTRNLCESAKNGGCGECQTSCQSACKTSCGIANQACE"
     CDS             10235..11629
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_118"
                     /sec_met_domain="PF04055 (E-value: 6.1e-14, bitscore: 46.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.8e-13, bitscore: 43.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 4.4e-19, bitscore:
                     62.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 2.1e-25,
                     bitscore: 82.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHQYKMFNQNIVLDICSGSIHVVDEIVYDMIAEFLDKDKNALVL
                     EMKEKYPSVETSELEECYDQILELKEQGRLFSEDTYEPMAGQLKAKTSGVIKALCLHIA
                     HTCNLNCSYCFASQGKYHGDRALMSFETGKRALDFLVENSGTRRNLEVDFFGGEPLMNF
                     DVVKQLVAYARSIEKEAGKNFRFTLTTNGMLIDDDVIEFANKEMSNVVLSLDGRKEVHD
                     RYRVDYSGKGSFDTIVPKFQKLVKAREGKNYYMRGTFTHANPDFLKDVQQMLDLGFREL
                     SMEPVVAKSDDPAALTKADREIVMKQYEDLAKLMLDYDDKKDPFTFYHYMIDLKGGPCI
                     YKRISGCGSGTEYMAVTPWGDLYPCHQFVGEEAFKLGDIYTGVTNKKVQNEFASCNVYA
                     RKECADCWARLYCSGGCAANAYHATGSVKGVYKEGCELFCKRLECALAVAIIRDMKENS
                     HEDADC"
     aSDomain        10238..11584
                     /aSDomain="TIGR03974"
                     /aSTool="tigrfam"
                     /description="rSAM_six_Cys: SCIFF radical SAM maturase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_118_0008"
                     /evalue="2.60E-227"
                     /identifier="TIGR03974"
                     /label="ctg1_118"
                     /locus_tag="ctg1_118"
                     /protein_end="450"
                     /protein_start="1"
                     /score="753.0"
                     /tool="antismash"
                     /translation="IHQYKMFNQNIVLDICSGSIHVVDEIVYDMIAEFLDKDKNALVLE
                     MKEKYPSVETSELEECYDQILELKEQGRLFSEDTYEPMAGQLKAKTSGVIKALCLHIAH
                     TCNLNCSYCFASQGKYHGDRALMSFETGKRALDFLVENSGTRRNLEVDFFGGEPLMNFD
                     VVKQLVAYARSIEKEAGKNFRFTLTTNGMLIDDDVIEFANKEMSNVVLSLDGRKEVHDR
                     YRVDYSGKGSFDTIVPKFQKLVKAREGKNYYMRGTFTHANPDFLKDVQQMLDLGFRELS
                     MEPVVAKSDDPAALTKADREIVMKQYEDLAKLMLDYDDKKDPFTFYHYMIDLKGGPCIY
                     KRISGCGSGTEYMAVTPWGDLYPCHQFVGEEAFKLGDIYTGVTNKKVQNEFASCNVYAR
                     KECADCWARLYCSGGCAANAYHATGSVKGVYKEGCELFCKRLECALAVAI"
     PFAM_domain     10532..10891
                     /aSDomain="Fer4_12"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13353.8"
                     /description="4Fe-4S single cluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_118_0011"
                     /evalue="1.70E-11"
                     /label="ctg1_118"
                     /locus_tag="ctg1_118"
                     /protein_end="219"
                     /protein_start="99"
                     /score="44.8"
                     /tool="antismash"
                     /translation="CLHIAHTCNLNCSYCFASQGKYHGDRALMSFETGKRALDFLVENS
                     GTRRNLEVDFFGGEPLMNFDVVKQLVAYARSIEKEAGKNFRFTLTTNGMLIDDDVIEFA
                     NKEMSNVVLSLDGRKE"
     aSDomain        11273..11524
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_118_0009"
                     /evalue="9.30E-18"
                     /identifier="TIGR04085"
                     /label="ctg1_118"
                     /locus_tag="ctg1_118"
                     /protein_end="430"
                     /protein_start="346"
                     /score="62.5"
                     /tool="antismash"
                     /translation="CGSGTEYMAVTPWGDLYPCHQFVGEEAFKLGDIYTGVTNKKVQNE
                     FASCNVYARKECADCWARLYCSGGCAANAYHATGSVKGV"
     CDS             11610..12938
                     /NRPS_PKS="Domain: Aminotran_5 (56-234). E-value: 3.6e-07.
                     Score: 21.2. Matches aSDomain:
                     nrpspksdomains_ctg1_119_Aminotran_5.1"
                     /NRPS_PKS="type: other"
                     /locus_tag="ctg1_119"
                     /transl_table=11
                     /translation="MKTPIVNFLKSYQEKSPVRMHMPGHKGAGILGFEGMDLTEIYGAD
                     ELFAVEGIIKESEQNASSLFGCPTYYSTQGSTLCIQTMCTILCQDAKSKGKKPKILAGR
                     NAHRSFIHAAALLDFEIEWLYGNSDYLSCTISTETLEKEIVENNPTAVYLTNPDYLGNL
                     LDIKSLASICKKHDVLLAIDNAHGAYLRFLEPSLHPIDLGADLCCDSAHKTLPVLTGGA
                     YLHLSDSLNQVWKNDVKHFMEYFSSTSPSYLIMASLDAANEVLDTTFKKSLSECIQRVD
                     VLKNALIQHGYTILSGEPMKITISTKEFGYTGNEIANFLMECDIYPEFYDSDYIVLMPS
                     PYNTKDDLKRLETCLCKIERKSVVFNSFPKLERARKVMSVRQALFAPSTMIEVSKSLGQ
                     VCSSVSVSCPPAILPVIPGEVISKSAIEVMKYYGIETVRVVKE"
     PFAM_domain     11616..12470
                     /aSDomain="OKR_DC_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01276.22"
                     /description="Orn/Lys/Arg decarboxylase, major domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_119_0012"
                     /evalue="3.40E-30"
                     /label="ctg1_119"
                     /locus_tag="ctg1_119"
                     /protein_end="287"
                     /protein_start="2"
                     /score="105.2"
                     /tool="antismash"
                     /translation="TPIVNFLKSYQEKSPVRMHMPGHKGAGILGFEGMDLTEIYGADEL
                     FAVEGIIKESEQNASSLFGCPTYYSTQGSTLCIQTMCTILCQDAKSKGKKPKILAGRNA
                     HRSFIHAAALLDFEIEWLYGNSDYLSCTISTETLEKEIVENNPTAVYLTNPDYLGNLLD
                     IKSLASICKKHDVLLAIDNAHGAYLRFLEPSLHPIDLGADLCCDSAHKTLPVLTGGAYL
                     HLSDSLNQVWKNDVKHFMEYFSSTSPSYLIMASLDAANEVLDTTFKKSLSECIQRVDVL
                     KNAL"
     aSDomain        11778..12311
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_119_Aminotran_5.1"
                     /evalue="3.60E-07"
                     /label="ctg1_119_Aminotran_5.1"
                     /locus_tag="ctg1_119"
                     /protein_end="234"
                     /protein_start="56"
                     /score="21.2"
                     /tool="antismash"
                     /translation="SEQNASSLFGCPTYYSTQGSTLCIQTMCTILCQDAKSKGKKPKIL
                     AGRNAHRSFIHAAALLDFEIEWLYGNSDYLSCTISTETLEKEIVENNPTAVYLTNPDYL
                     GNLLDIKSLASICKKHDVLLAIDNAHGAYLRFLEPSLHPIDLGADLCCDSAHKTLPVLT
                     GGAYLHLSDSLNQVW"
     CDS             12904..13128
                     /locus_tag="ctg1_120"
                     /transl_table=11
                     /translation="MVLKLYVLSKNKLIAGGKEYPYDSVIMAVGSKANDTSMYANLGIP
                     TYIVGDCKKAGIALDAFKDAYHAVLEINK"
     CDS             complement(13133..13870)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1159:dihydropteridine reductase (Score: 46.2; E-value:
                     6.4e-14)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_121"
                     /sec_met_domain="PF00881 (E-value: 6.8e-23, bitscore: 75.3,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPIIQSLFDRKSCRIFEDKEISQEDKTLILQAAMQAPSAGNQQM
                     YTIIDVQDKKLQETLSKTCDNQPFINQAKMILIFCADFQKWYDLFKYENRNPRKPGVGD
                     LLLATTDATIAAQNAVVAAESLGIGSCYIGDILEQHDLHKELLNLSEYVVPVCMLVLGY
                     PAEDHFKRQKPKRCKLEDIICVDQYHRKDKQELKNMFEHKAGNKTLNEWATTFCNRKYN
                     SDFSKEMTNSVQKYIDQFKSEAD"
     PFAM_domain     complement(13382..13843)
                     /aSDomain="Nitroreductase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00881.26"
                     /description="Nitroreductase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_121_0013"
                     /evalue="2.80E-20"
                     /label="ctg1_121"
                     /locus_tag="ctg1_121"
                     /protein_end="163"
                     /protein_start="9"
                     /score="73.2"
                     /tool="antismash"
                     /translation="DRKSCRIFEDKEISQEDKTLILQAAMQAPSAGNQQMYTIIDVQDK
                     KLQETLSKTCDNQPFINQAKMILIFCADFQKWYDLFKYENRNPRKPGVGDLLLATTDAT
                     IAAQNAVVAAESLGIGSCYIGDILEQHDLHKELLNLSEYVVPVCMLVLGY"
     CDS             13927..15597
                     /locus_tag="ctg1_122"
                     /transl_table=11
                     /translation="MKLKEIKKNAHKNVKTHYATYLVLCLAAVLMGSEFSSTLSLLKQD
                     NAKSVSGLLMHSSFVKSMTSLLPEGVFGTTNGVFAHVVNGITSGSFVKTLFLGLSTIIH
                     SKDIASICFVVIGLCISVFYRVYIVNVLPVINRRLFLEGRVYAKLPLDRLVYLMRIRKQ
                     MHVAFVKLVKSIILTIMNFTVVGGVYFYYVYFLVDYILAENPTISLKDALSLSRNMMKG
                     HKFECFKWQFSMAGWYILDVCTFGISAIFYSNMYRMSVMCEFYTLRRKEFQSAILNDTY
                     LFEKPSSALMRNTYSDVIAALNAKNPMENAYTGVKKFLCDNFGIIFHLSSKEKQYERYT
                     YNKMEAETMITEVYLLCYPVRLSPIEEAYKKSNLRVLHPNRNYTVTSILVCFFFMCFVG
                     WIWEVSLSMISYGRFVNRGVLHGPWIPIYGFGCVLILLLLKRFRMRPKVEFSMAVLLCG
                     CIEYFTGFFLELTHNGQKWWDYTGYFLNLDGRICAEGLLVFGVGGMAFVYVIAPLVDNW
                     VKEHLNKRLSTACLVLLLLFGTDVVYSHFEPNVGEGVTG"
     PFAM_domain     13930..14724
                     /aSDomain="DUF975"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06161.13"
                     /description="Protein of unknown function (DUF975)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_122_0014"
                     /evalue="7.50E-16"
                     /label="ctg1_122"
                     /locus_tag="ctg1_122"
                     /protein_end="266"
                     /protein_start="1"
                     /score="58.8"
                     /tool="antismash"
                     /translation="KLKEIKKNAHKNVKTHYATYLVLCLAAVLMGSEFSSTLSLLKQDN
                     AKSVSGLLMHSSFVKSMTSLLPEGVFGTTNGVFAHVVNGITSGSFVKTLFLGLSTIIHS
                     KDIASICFVVIGLCISVFYRVYIVNVLPVINRRLFLEGRVYAKLPLDRLVYLMRIRKQM
                     HVAFVKLVKSIILTIMNFTVVGGVYFYYVYFLVDYILAENPTISLKDALSLSRNMMKGH
                     KFECFKWQFSMAGWYILDVCTFGISAIFYSNMYRMSVMCEFYT"
     PFAM_domain     15097..15558
                     /aSDomain="ABC_trans_CmpB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06541.13"
                     /description="Putative ABC-transporter type IV"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_122_0015"
                     /evalue="1.30E-41"
                     /label="ctg1_122"
                     /locus_tag="ctg1_122"
                     /protein_end="544"
                     /protein_start="390"
                     /score="142.4"
                     /tool="antismash"
                     /translation="CFFFMCFVGWIWEVSLSMISYGRFVNRGVLHGPWIPIYGFGCVLI
                     LLLLKRFRMRPKVEFSMAVLLCGCIEYFTGFFLELTHNGQKWWDYTGYFLNLDGRICAE
                     GLLVFGVGGMAFVYVIAPLVDNWVKEHLNKRLSTACLVLLLLFGTDVVYS"
     CDS             15594..16304
                     /locus_tag="ctg1_123"
                     /transl_table=11
                     /translation="MIKKLNGNQIKMIAIIAMFMDHFATTLYSNYEKFWWLLLIHLIGR
                     VAAPIMWFMVVEGYTHTHSLKKYLERLLIFSIIAHFAYNFCFGISLIPLKDSLLNQTSI
                     IWSLFLSVIGLWVEDQEWKDVKKIGCILILCLLAFPSDWSCFPVLCTNHIYKNQGNLKK
                     QVLGMALYISMYVFVYCLCIDVVYGLLQFGIVLVYPIMSLYDGTRGKSTFMKWFFYWFY
                     VGHLVFCGLIRVMM"
     PFAM_domain     15612..16292
                     /aSDomain="TraX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05857.13"
                     /description="TraX protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_123_0016"
                     /evalue="6.20E-26"
                     /label="ctg1_123"
                     /locus_tag="ctg1_123"
                     /protein_end="233"
                     /protein_start="6"
                     /score="91.8"
                     /tool="antismash"
                     /translation="GNQIKMIAIIAMFMDHFATTLYSNYEKFWWLLLIHLIGRVAAPIM
                     WFMVVEGYTHTHSLKKYLERLLIFSIIAHFAYNFCFGISLIPLKDSLLNQTSIIWSLFL
                     SVIGLWVEDQEWKDVKKIGCILILCLLAFPSDWSCFPVLCTNHIYKNQGNLKKQVLGMA
                     LYISMYVFVYCLCIDVVYGLLQFGIVLVYPIMSLYDGTRGKSTFMKWFFYWFYVGHLVF
                     CGLIR"
     CDS             16318..16899
                     /locus_tag="ctg1_124"
                     /transl_table=11
                     /translation="MRRKVRRVPVVLDAGEIKDLPQEDIRMILRGADELISTGGRSMLA
                     KILKGSKDKKIFEHKLNECPAYGYYQDMKLDDIAKCIDWMIKKDYLRIEYDYRLPLLVF
                     SEKGWQIEKETFAQELYQRICLDVEEKKARVIFEMKEVNRQVVMRVLDKIEKDGTKKFL
                     PYLEAWKMLEVKKVAARIIEVENKIVGKDM"
     PFAM_domain     16384..16665
                     /aSDomain="RQC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09382.12"
                     /description="RQC domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_124_0017"
                     /evalue="2.00E-11"
                     /label="ctg1_124"
                     /locus_tag="ctg1_124"
                     /protein_end="116"
                     /protein_start="22"
                     /score="43.8"
                     /tool="antismash"
                     /translation="EDIRMILRGADELISTGGRSMLAKILKGSKDKKIFEHKLNECPAY
                     GYYQDMKLDDIAKCIDWMIKKDYLRIEYDYRLPLLVFSEKGWQIEKETF"
     CDS             17284..18045
                     /gene_functions="transport (smcogs) SMCOG1044:ABC
                     transporter, permease protein (Score: 143; E-value:
                     1.5e-43)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_125"
                     /transl_table=11
                     /translation="MKKNRRIVMPLLVFILVIGGWELYVRAFDISLYILPSPSKIISAL
                     IENMDILMQHSLVTLEESVLGLLISTFFAIVISIGMDLSKTFKTSIYPYLIVTQTVPIM
                     VLGPLFSIWFGFDLLPKILIVIFMCFFPIAISFTDALSQVSEKEINLLKSFGANLFQIY
                     KIVKIPSGAIGLFSGLKVAATYCVGGAIVGEWLSSRAGLGYYMLRVKNGYMLDKVFACV
                     LMIIFWSILLNLGVSLLEKILFPHLRKGERK"
     PFAM_domain     17506..18030
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00528.24"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_125_0018"
                     /evalue="8.60E-24"
                     /label="ctg1_125"
                     /locus_tag="ctg1_125"
                     /protein_end="249"
                     /protein_start="74"
                     /score="84.4"
                     /tool="antismash"
                     /translation="IVISIGMDLSKTFKTSIYPYLIVTQTVPIMVLGPLFSIWFGFDLL
                     PKILIVIFMCFFPIAISFTDALSQVSEKEINLLKSFGANLFQIYKIVKIPSGAIGLFSG
                     LKVAATYCVGGAIVGEWLSSRAGLGYYMLRVKNGYMLDKVFACVLMIIFWSILLNLGVS
                     LLEKILFPHLRK"
     CDS             18042..19040
                     /locus_tag="ctg1_126"
                     /transl_table=11
                     /translation="MKILKAMCAAAVALSLVGCAQTSNSDDKLTKVTLMLDYTPNTNHT
                     GFYVAKNKGYYKEAGLDVDIIEPGDNATTSMVAAGKADFGVSYQEDVTYALTSEDPLPI
                     KTIATIIQHNTSGFVSLKSANINSVKDFEGKTYAGWGAPSEEAVIKAVMNEAGADFSKL
                     NIVGSDGSGIAGLSDEVGKNKVNLGWEFYGWAIIKALQDGYDLNYMPLADLDSRLDYYT
                     PVIITNNKMIKKNSDIIQKFMEATKKGYEYAIDHPSKAAEILHDDALTDTDLKFLKESQ
                     KYLSSQYAKDADSWGVMKDSVWDNYTDFMYETGLIDHKIDAKDQYTNEFVK"
     PFAM_domain     18162..18821
                     /aSDomain="NMT1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09084.13"
                     /description="NMT1/THI5 like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_126_0019"
                     /evalue="1.60E-70"
                     /label="ctg1_126"
                     /locus_tag="ctg1_126"
                     /protein_end="260"
                     /protein_start="40"
                     /score="237.5"
                     /tool="antismash"
                     /translation="NTNHTGFYVAKNKGYYKEAGLDVDIIEPGDNATTSMVAAGKADFG
                     VSYQEDVTYALTSEDPLPIKTIATIIQHNTSGFVSLKSANINSVKDFEGKTYAGWGAPS
                     EEAVIKAVMNEAGADFSKLNIVGSDGSGIAGLSDEVGKNKVNLGWEFYGWAIIKALQDG
                     YDLNYMPLADLDSRLDYYTPVIITNNKMIKKNSDIIQKFMEATKKGYEYAIDHPSKA"
     CDS             19040..19774
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 176.1; E-value:
                     1.5e-53)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_127"
                     /transl_table=11
                     /translation="MKLQVEKLNLEFSGKEILHDISFSIQEGEFVSILGPSGCGKSTIL
                     NILAGLIEDYSGQLFVDDERIKGVSSHFAYMPQNDLLLEWRTILDNVCLYGEINHDKSM
                     KQRALKEFETFGLSGYENAYPSSLSGGMRQRAAFLRTSLCKADILLLDEPFGALDVITR
                     NDMQDWLLQLRKNYNRTTLLVTHDIDEALYLSDRILILSNKPSRILQEIDLSKEKKSRD
                     WLFSQSVLKKQVYELLKGENHA"
     PFAM_domain     19091..19504
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_127_0020"
                     /evalue="2.60E-28"
                     /label="ctg1_127"
                     /locus_tag="ctg1_127"
                     /protein_end="155"
                     /protein_start="17"
                     /score="99.3"
                     /tool="antismash"
                     /translation="LHDISFSIQEGEFVSILGPSGCGKSTILNILAGLIEDYSGQLFVD
                     DERIKGVSSHFAYMPQNDLLLEWRTILDNVCLYGEINHDKSMKQRALKEFETFGLSGYE
                     NAYPSSLSGGMRQRAAFLRTSLCKADILLLDEPF"
     CDS             19767..20450
                     /locus_tag="ctg1_128"
                     /transl_table=11
                     /translation="MHDAHYHYSKEINALQNEYDISGICNVANEKEFELVQQKQLFYSC
                     GVHPWNASLDTFESMLPLLKKAPIIGEIGMDSVWCDVDLKIQKEVFEKQLQLAQALNKP
                     VILHTKGQEKTILELIRKYPNTYVVHWYGCMDYVKEYDEVVSYFTIGPSIGKEEEVTHL
                     VKQISMDKLLMESDGIEAVKWAIDSDDYLAALKNEITMVASLKNQSYYEVERILDHNFS
                     KLIKK"
     PFAM_domain     19866..20441
                     /aSDomain="TatD_DNase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01026.23"
                     /description="TatD related DNase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_128_0021"
                     /evalue="1.60E-28"
                     /label="ctg1_128"
                     /locus_tag="ctg1_128"
                     /protein_end="225"
                     /protein_start="33"
                     /score="99.9"
                     /tool="antismash"
                     /translation="ELVQQKQLFYSCGVHPWNASLDTFESMLPLLKKAPIIGEIGMDSV
                     WCDVDLKIQKEVFEKQLQLAQALNKPVILHTKGQEKTILELIRKYPNTYVVHWYGCMDY
                     VKEYDEVVSYFTIGPSIGKEEEVTHLVKQISMDKLLMESDGIEAVKWAIDSDDYLAALK
                     NEITMVASLKNQSYYEVERILDHNFSKLI"
     CDS             complement(20465..21595)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1178:cobalamin synthesis protein/P47K family protein
                     (Score: 303.1; E-value: 4.4e-92)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_129"
                     /transl_table=11
                     /translation="MKRKSIPILLLTGYLGAGKTTLLNHILKNQEGYKVAIIVNDIGEI
                     NVDQKLIDKNAQIQKEDTDVVGLTNGCICCTLKLDLLQQLSALASSNKFDYIIIEASGI
                     CEPIPIAQTITAANETLYSRGLPELFHLDNIICVADAARLSNEFNCGKHLLEPVEDEDS
                     LDSLLMQQLEFCNTVILNKAETVNEDEKNEIKAVIHKLCKDAGIIEASFGQVNLEELLN
                     THNFDYEKAQNSIGWLHEIEEHEHHHDHEHEGEALEYGISTFVWQTRKPLDLKKFTNLL
                     NNYPNVIRTKGYVWFDNQPDSAYLFEQAGKLTSLTEDSLWIASAPKQDQIDLLKANPQL
                     AKNWDEEYGDRINQLVFIGKNMDEEQIKRQFNDCLA"
     PFAM_domain     complement(20471..20815)
                     /aSDomain="CobW_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07683.16"
                     /description="Cobalamin synthesis protein cobW C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_129_0023"
                     /evalue="2.90E-24"
                     /label="ctg1_129"
                     /locus_tag="ctg1_129"
                     /protein_end="375"
                     /protein_start="260"
                     /score="84.9"
                     /tool="antismash"
                     /translation="ISTFVWQTRKPLDLKKFTNLLNNYPNVIRTKGYVWFDNQPDSAYL
                     FEQAGKLTSLTEDSLWIASAPKQDQIDLLKANPQLAKNWDEEYGDRINQLVFIGKNMDE
                     EQIKRQFNDCL"
     PFAM_domain     complement(20972..21577)
                     /aSDomain="cobW"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02492.21"
                     /description="CobW/HypB/UreG, nucleotide-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_129_0022"
                     /evalue="1.40E-48"
                     /label="ctg1_129"
                     /locus_tag="ctg1_129"
                     /protein_end="208"
                     /protein_start="6"
                     /score="164.9"
                     /tool="antismash"
                     /translation="PILLLTGYLGAGKTTLLNHILKNQEGYKVAIIVNDIGEINVDQKL
                     IDKNAQIQKEDTDVVGLTNGCICCTLKLDLLQQLSALASSNKFDYIIIEASGICEPIPI
                     AQTITAANETLYSRGLPELFHLDNIICVADAARLSNEFNCGKHLLEPVEDEDSLDSLLM
                     QQLEFCNTVILNKAETVNEDEKNEIKAVIHKLCKDAGII"
ORIGIN
        1 tgccggaatg gacaaatacc gcattgagcg ttgttgcttc catatatatg tcggccttaa
       61 aaatgatgat tttcccactt gtatttacaa gtttagtcat gggaattatt ggtattgggg
      121 atattgccaa aacaggtaaa gttggtttac atgccttatt atggtataca ggtacaacag
      181 ctttggcttc tggtttagga ttggttttac ctcgtttatt acatttgggc cagaatgcac
      241 atattgtggc aaccaagact caagtagaag cagctacatt taatggtttg ttggatactt
      301 tacagaatat tattccttca aatccagtag aggcattcgc aacaggaaat atgcttcaag
      361 tattagcttt tgccgtaatt attggacttg cttgtttggc aatcaaggaa aaagcagatc
      421 catttgtgaa tttgtgtgat tccatttatc aaatttctat ttttattatt agtaaaatta
      481 tgtatgtgac tccatttgga gtattcgcat gtattgccac agttatgtat tcaaatggtg
      541 tggatacaat gcttcaatta ggacaagtat tattggcttt atatattacg ttctatttat
      601 atgcatttat tgtttatggt ggtatggtta aattctttgg aaaatatagt ccaattcaat
      661 tttttaaaga tattgcacca gcaggattga atgcgtttgg aacttgttca agtagtgcta
      721 cgattcctat ttcattaaag tgtgcttcag aaaagattgg gattcctgaa gaaattacat
      781 ctttaacttt acctttgggt gcaacaatca atatggatgc tgtttcgatt ttgatgtcat
      841 ttatgattac attttttgcg acagctttag gtattgattt aagtattgga acaatggtaa
      901 ctgtccttgc ttgtaacgta ttgttaagtg ttggtactcc aggcgttcca ggtggtgcta
      961 ttgctgcttt tgcggcattg tgtccaattg caggaattcc aacaaatcaa atcctaggtg
     1021 tttatatttc agtaaatact ttgtgtgaca tgggagctac ttgtgtgaat gtcattggtg
     1081 acttggcttg ttcaactgta ttaaagcaga ccttacattt taaaaagaaa aaataggatg
     1141 aagacaaata aaacaatcag tgaatttaaa gagtttatcg ccaaaggcaa tgtgatggat
     1201 atggctgtgg gaaaatcgtt acttccttgg taaatgatat attgatgccg attgtgggta
     1261 ttttaattgg tggacttgat tttacaggtt taaaaattca agtaggtaca gttgcaatta
     1321 cgtatggtaa ttttattcaa aatgttgtag attttttaat tgtagcggca tgcatcttta
     1381 caatgttaaa atttttggct cattttaaaa agacaacgaa tgatcaactt gatcaaaaag
     1441 aatctaaaca agatgatact gttgtcttat tggaagaaat tcgtgatttg ttaaagaaga
     1501 tagataaagt aaattaaata tgtgatcaac aagagtatac cagctttttt gtcgagtact
     1561 cttgtttttt tagtgcaaag ataaaggaca agaccaatca atattgcgac aaaagaatca
     1621 ataataaagt gaggttcaaa aggtacggga gtaataagtg cacttgatcc tacgacaaat
     1681 aagatattaa agatattcga tccaatgatg tttccaatcg cgatatcggc attgcctttt
     1741 ttggctgctg ttacagaagt gacaagttct ggtaatgaag ttcctaaggc aacgattgtt
     1801 aggccgataa atctttgact gacaccgaat gaaatggcaa tgtttgtagc tgcatctacc
     1861 gcaaagttac ttccaatcat taaacataca agtccgagtg gaataaataa aggatttgtt
     1921 tgtttgattt cagtttcttc catttgattc ttagacattt taaaaatgta gtataagtaa
     1981 ccaagaaaga ataaccacat aataattcca tctaaacgag aaattgttgt gttgatacct
     2041 aataatatca atacaaatgt tacaagtatc ataaatggca tttcatattt catcgtacta
     2101 ttttgaatat gtaaaggacg aatcagtgct gtaatgccaa gaatgattcc tacgtttaga
     2161 atgttacttc caacaacatt tccaattgta atggcagcat tggattttaa agcagcagta
     2221 atagaaacaa aagcttctgg tagactcgtt cccatcgcaa cgatagtaag tccaataatc
     2281 agttggggta tgccaaaacg tgaggcgata ctactagctc catcgacaaa ccaatcggct
     2341 ccttttagca gtagaataaa tcctaatact aataaaatta tgttcatata gttcctcctg
     2401 gaccagataa aataaaaaga ctctggtctt atataccaaa gtcttgccat ttcatcacag
     2461 tccggattta atatcgtatt gacgaagctg taaacacata tatgtgcagg ctactccctt
     2521 tatgagcata ttatacatat tttgttcaat aaaatctatg tttcattgta aaaatatctt
     2581 aacaaatgca agttttctag aaaaacatca atttatttcg tattagatat agggggtgag
     2641 taaatcacgt gaataaaatt aaagacaaaa caatgaaaga atttctagaa aacaatgcct
     2701 attttgtcga cttctttaat gcatacttct ttgatggaga aagagttctt aaacctgaaa
     2761 actgtatgga acttgattca gagatgaatg attcgaatat ggatatagaa aagcatgtgg
     2821 atgtaattcg taagtacaat gatggaaatc tttatagtgc attcgttatt gaaaatcaaa
     2881 gttgtgtgga tatgtccatg gttgtaagag cggctgcata tgagtttgta gcgtatgaca
     2941 gaatgttaaa gaagttaaag aagaataagg ctaaagaaaa actacccatg gtgcacattc
     3001 ttgtgttcta tacaggagaa aggccttgga atgctgcaaa taagctttcc cagcttgtag
     3061 atgtggatga aagatttgaa tcgtattttc atgactacca aatgaatctg attgaaatca
     3121 caggaaatac ttcatataat tttaatgaag aagacgtaca taatctattc tatatatgtc
     3181 gaagtattta tgatcagtct atttatgaag gaaagagtaa tagctttgga tttgtgaaga
     3241 gcagtgtgtt aaaagtagtc aagacattaa cggatgtaga atggttggat ttagaagaat
     3301 tagaggaaaa ggaggagatt gaaatgtgtg aagctgaaaa gagatggctt gaagtaaagt
     3361 caaaagaatg ggaagctaaa ggaataaaaa aaggaatcga acaaggcatt gaacaaggaa
     3421 ttgaacaagg aattgaacag ggtagtgaga aaaaagagct tgagatgtat cgaaaaatga
     3481 tggacaaggg atttggaatt aaagctatcg catctatctt ctcagtaagt gaagagtcga
     3541 ttgaaaagct gctgatgaaa gcttaggtaa agctgaaaag agatggcttc gaaaaagaag
     3601 acacgttctt ttgttcaatg tttgtaacaa tggataccag gagatgaaaa atctcttctt
     3661 ttctttttcg tctgtgatat aataaggtga ctttgaaagg attgagaaaa tggtatttct
     3721 tttattagta ttaggtatgg tccttttaat gaagggtgca gacttgtttg tggatggtag
     3781 tgcaagtgtg gctcgtaaat taaaagtgcc ttcagttatt attggtttga caattgttgc
     3841 gctaggaaca agcttaccag aagcaagtgt gagtattaca gctggtttaa tgggcagtaa
     3901 tgaaattgcg atttcaaata ttgtgggttc taatattttc aacacgttgg ttgtggttgg
     3961 aacaagtgca gtcattactc cgtttttaat ggatcaggat attttgaatc gtgatttaaa
     4021 aatcaatatt ttagtgagta ttttactttc aatttttgtg ttgaatggaa tgttgaatcg
     4081 ctttgaaggt attatcttct tagtcggttt agtattgttt attttaaatt tgattcgtag
     4141 tgctaaaaag aatcgtgttg aggatgagaa agttgaaact ttatcgggaa tcaaatgcct
     4201 gatttatatc gtgattggtg ttgcgtgtat tatttggggt ggagatatca ctgtagatag
     4261 tgcaaaacag attgctgcta tgcttggtat gagtgatact ttgattggtt taactgttgt
     4321 ttcaattggt acttctttac ctgagttagt aacaagtgtt gttgcggcaa gaaaagggga
     4381 gagtggatta tctttaggaa atgcgattgg aagtaacatt atgaatattt tatttatttt
     4441 gggtgcttca agtacaattc atccaattgc ggctacttca cagaatatta ttgatacttt
     4501 tgtcttgatt ggtgtttctc tattaattta tggtattgcc aaaaagggag atacgatgac
     4561 aagaaaaaag gggatcttta tgatcctcgt atatgtcatt tatatgattt atattattgt
     4621 acgctaggct tgtcctagct ttttttcttt ccttgggaaa gaatagctcg aatagaatcg
     4681 aaaagaatgg gtttatattc ttcaatagga aggggttgac tatgaagaat actgttgtag
     4741 caagtacttc ctgtaagttc aactattaag tagagtatga cttctgaatt ttcaaattca
     4801 tatccatttg cggttgcgat ttcgttaaat tcttttataa gattgaaact atcattatca
     4861 atagctgtgt ttaactgggc atggaatact ccccaagata agtttctttc aacgaatttt
     4921 aaaatcaatg gattgttttc taatcgaatc aatacttgat tgatcaaaaa aatcacagag
     4981 tcttcaaaat tacgaatatc gtttttttct aattgtttgt gggcttcttc aaaaagacga
     5041 tgtgcttctt tttgaattag aatatcgcga atttggtatt tgtctttgaa ataaagatag
     5101 aaagttcctt ttgcgacacc tgcactcttt acaatatcat ttacagagac attcgtaatg
     5161 tcttcttttg tgaatagatt aaaggcagcc tgtaagaggt tgttttcttt tattttctta
     5221 ttttcgatta tcttactttt catgcatatc accatcctta ttataaacaa taatttagaa
     5281 aatacaaata aaaatgaccg attgaacata ttaaaacaat tgtatattag gaatttaaaa
     5341 aaaataaaac aaaattattg actagtggtc agtttggtac tatactcttc acgtagtaaa
     5401 ggaaaggata gaaaaaaagg tgattcgata tggataagat gtcaaaatgg atagttaaat
     5461 atcgtaattt gattttggcc gtagccatca tactattaat tccaagcgca attggttatt
     5521 tcaatacaaa tattaattac gatttattat cttatttacc ttcaacttca gaatctatga
     5581 aaacacaaaa gattcttggg gatgatttta acttatcgag tgtagacttc ttggttgtca
     5641 acaacaaatc agatcaagag gccgcaaaaa ttaaggaaga gatcaataaa attgatggag
     5701 ttgaaaaatg tatttggaga gatgatgtat tagatatttc agttccaaaa caggcaattc
     5761 cagaaagcat tcaagatatg ctttattctg gcaacagtac aatgatgatt gttacattta
     5821 aagagccaac atcatcaatg cgtacaatga atgcgattag taaaataaaa aaatatacaa
     5881 aagatgattg ttacttaggt ggtatgtcag ccatcagtga agatactaaa gatcaaacag
     5941 aacatgatac accaatttat gcaggcattg ccgttgtatt atgtatggtc gtattgttct
     6001 taggattaga gagtacaatt gctccagttg tatttatgtt aggaatgatt ttcccaattg
     6061 tttataactt tggtacaaac gtattcttag gtgaaattag ttatatcaca aaggctttgg
     6121 ccgttgtatt acagttagct gtaactttgg attattccat cttcttatta catagatatc
     6181 aagaagaaaa acaaaaactt ccaaatgaag aagctatggc aaaggctatc aaagctacgt
     6241 ttacttcaat tacttcaagt tcaatcacaa caattgcagg tttcgttgcc ttgtgtgtaa
     6301 tgcagttaac actaggtaga gatattggta ttgtcatggc aaaaggtgtt gttcttggtg
     6361 tattatcaac catctttatt ttgccaagct tgttgatgtt ctttgataag acgattgaaa
     6421 agtacaaaca caaaacaatt ttgaatgagt tacatagagt acctcgtttt gtgattcatc
     6481 actataaaaa gattcttgtt gccttcgtgt tgattttcat tccatttgga tatggacagt
     6541 cacatacaaa tatctattat gatttgattt ctggtatgcc aggtgatttt gcgagtatca
     6601 ttggtacaaa tcagttaaaa gataaatttg atatgacaac aacacatttc gttttagtgg
     6661 atgacaaatt aacgacaaac gaaattcaga atatgtgttc tgaaatcaaa gatttaaaag
     6721 gaattcataa cgtattggct tatgaagaat ttgtgggtcc aggacttgca tccaacttta
     6781 ctccaagtgt agtaaaggat attttccaaa atggtggaaa gaaattaatt gttgtgaaca
     6841 gtgattataa agctgcaaca aacgagttaa atacacagtt agacaaaatg gataccatca
     6901 ttcataaata tgataagaag ggtatgattg gtggagaagg aagtatgaca cgtgatttga
     6961 tcacaacaac aaatacagac tttgcgatgg ttaacgtatt atccgttatt atgatcttta
     7021 tcattgttgc cttaacattt aaatcatttg cacttccagt cattttagta ttaacaattg
     7081 aatttgcgat cacaatcaat atgggtattc cattctttac aaaaactaca cttccattta
     7141 tcgcaagtat ggttatcgga accattcaat tgggagctac cgttgactac gctatcctaa
     7201 tgacaacgcg ttttaaagaa gagttatcgc atggtaagaa ggttaaggaa gcggctttga
     7261 ttgcgatgga aaaatcgagt gtttccatta tgacaagtgg attctcgttc tttgccgcat
     7321 gtatcggtgt aagctttgta gctaagatgg atttaattaa atcattagtc attttattag
     7381 cacgtggtgc tttaatttca gtcgtaagta ttttattagt attaccttca ttgttgattt
     7441 tctgccacaa gttcatcgaa aagacgacaa aggactggcc agaatcaaac atggaagcga
     7501 aaggagaata aatatgaatt taagtcatac agtaaaagta gttggtagtg tagtgttgag
     7561 tgcagttatg gcaggaagta tgatgcctgt gactgtattt gcacaaaata atgatgaaaa
     7621 tcctacagaa aaaacagaaa ctgtttattc tgtattaaac tcagatggtt ccatcagtga
     7681 tacaatcgta tctagctggt tacatgatga ggatggaatt aataatatta aagaaacttt
     7741 aaacttaaca gatgttaaga acattaaatc aaatgaaaaa ccttcaaaaa atggaaatac
     7801 atatacatgg aatgcgaaag gaaatgatgt gtattatgaa ggaacagcca caaaacaact
     7861 tcctgtgtct gttaagcttc gttatgaatt agatggtcag gaaatgtctg caaaagatat
     7921 ggaaggtaag tctggtcatt tgaaattaac tatttctttc acaaataact attcagaagt
     7981 aaaaaatatt aatggaaaat ccattgtgat tcaccctagt tatttagctg gtggtatgtt
     8041 gaatatgagt actggtaact ttacaaatgt gaagtgtgaa tctggtaaga ttgtaaatga
     8101 tggaacaaat gaaatgttgg catttgcgaa tattccaggc ttgaatgaaa cattaagatc
     8161 agctggttta gacaaagtaa ataatcaatt aggaattagt gatgatgtaa cagtagaagc
     8221 ggatgtcaat aattttgatt taggttctat catggttggt atgacaaatg aaattgattt
     8281 ggcaagtgaa ttaggtgaaa ttggttctgt atctgaatta acagatggaa ttgatcaatt
     8341 aatggatgct gatgatcaat tgatcgatgg ttctaaacaa ttgtatgatg gaacaacaca
     8401 attaaaagaa ggtattgctc cattatcaag tgcttatcct caaattgaaa cattaacaaa
     8461 tgcatttgat caattacatg atggaacaac aactttaagc actggtttaa atcaatatac
     8521 ggctggtgtg gatcaattaa atgtcgttag taaacaaaat ttatataaat tatcaatggg
     8581 tgctacaaca ttaaatacat ctttaaataa caaagaatca aagagtcaat taaatcaatt
     8641 ggttcaagga tctcaagctt tggatgctgg tattcagaat ctaaatgaac aagtaaatgg
     8701 cgatgacagt atgttaaaac cagatatggt aaaaaatctt actgaagctt taaagactac
     8761 gaatgaacag gttggaaaat taggacaagt attgaatgat ttacaagatc aagaaggtgc
     8821 atttgttgat ttaagcaatc aaattacaaa agccagtgaa aatattaata aattaggaac
     8881 tctacaaaca agttttaaag aagttacaga tggagcatct gcaattatta ctgcagataa
     8941 tgaacaaatt aagagtgttg atgatcaatt agctgctatt cgtacaaaag aaatcaacgc
     9001 attaaatgct tcaattgaag cgttaaaaaa tgctgccaat gctgttccag aagatgatac
     9061 aactggagct aaagctaaga ttgaagaaca aattaatgca ttagaaagcc agaaagcgac
     9121 attaggagat gcgtcttcat taagtgttac attgaaagat ttaagtcaat gtcaggcggg
     9181 tattgataaa attgttgcgg attcaaagga aactttagaa gaattaaatg ctgtttataa
     9241 tagttctaaa actgacatta agaatcttag tacaaaattg gatgaagcta aaaagtcaat
     9301 tgaagtttta aatggcgtaa tgaagcaatt aaatgaaaat ggcataacta gtgaagagtt
     9361 tgaaaaaaag gtgaatactt taaaagcagg agttgaaaaa ttagcaaaga attcacctgc
     9421 tttagctaat ggtgtagcca ctctagcaaa caaattaaat aatttaggtg aaggcttaaa
     9481 tggcttagat tcaggtatgt ctcaggctta tacaggaata actcaagcaa caagtcaatt
     9541 atctgataac agtgattctt taagaaatgg tgcaaaagca ttaaatgatg gaactgcaca
     9601 attaagtgca tctaagtcaa agatgagcga attaactagt ggattaacta aattaagtga
     9661 tgccgttgat caattgaatg atggagctca acaattatac gaaggtaatg aacaattcaa
     9721 gtctgaagga ttggatcaat taaaagaaaa ggttgattta ggtgttggag aacttgaaac
     9781 gttacaaagc gtaatgaatg aaatcaaagc tatgaacaaa gaatatgctt catactctgg
     9841 tgctccagaa ggtgctacag taacgagtcg ttacgtattc cgtactaagg aagaaagttc
     9901 taaatagttt ataaaggtat tcttcggaat gcctttttaa tttgatatta ttcgtttggc
     9961 gtgttaaaat aaaagggaat ttatatgggg gtatataatc atgaaacata ttaatacagt
    10021 agatactcgt aacttgtgtg aaagcgcaaa aaatggtgga tgtggagaat gccaaacttc
    10081 ttgccaatca gcttgtaaaa ctagctgcgg aatcgcgaac caagcttgcg aacataataa
    10141 agaaagtaag taattaagaa atgccgaagt gattcggcat ttttaatgcc gcctttaagg
    10201 cagcattttt ttaaattttg aggaggaaat atagatgatt catcagtata agatgtttaa
    10261 tcagaatatt gtattggata tttgttcagg aagcattcat gtggtagatg aaattgttta
    10321 tgatatgatt gctgaatttt tagataaaga taaaaatgct ttggttttag aaatgaagga
    10381 gaaatatcct agtgtagaaa catctgaatt agaagaatgt tacgatcaaa tcttagaatt
    10441 aaaagaacaa ggtcgtttgt ttagtgaaga tacatatgaa cctatggcag gccaattaaa
    10501 agctaagaca agtggcgtta ttaaagcttt atgtcttcat attgcccata cttgtaactt
    10561 gaattgttct tattgttttg caagccaagg aaaataccat ggggaccgtg cattaatgag
    10621 ttttgaaaca ggaaaacgcg ctcttgattt cttagtggaa aattcaggaa cacgcagaaa
    10681 cttagaagta gatttctttg gtggagagcc actaatgaac tttgatgtgg ttaaacaatt
    10741 agttgcctat gctcgtagca ttgaaaaaga agccggaaag aatttccgct ttacattaac
    10801 gacaaatggt atgttgattg atgatgacgt aattgaattt gcgaacaaag aaatgagcaa
    10861 cgttgtatta agcttagatg gacgtaaaga agtgcatgac cgttatcgtg tggattattc
    10921 tggtaaggga agttttgata caatcgttcc taaattccaa aagttagtaa aggctcgtga
    10981 aggtaaaaat tactatatgc gtggtacttt tactcatgcc aatccagatt tcttaaaaga
    11041 tgtgcaacaa atgttagatt taggttttag agaattaagt atggaacctg tggttgccaa
    11101 gtcagatgat cctgcagcac taacaaaggc agatcgtgaa attgttatga aacaatatga
    11161 agatttagca aagttgatgc ttgattatga tgataagaaa gatccattta ctttctatca
    11221 ctatatgatt gatttaaagg gcggaccatg tatttataaa cgtatttcag gatgtggttc
    11281 aggaactgaa tatatggccg ttacaccatg gggagattta tatccttgtc accaatttgt
    11341 aggagaagaa gcctttaaat taggagacat ttatacgggt gtcacaaaca aaaaggtcca
    11401 gaatgaattt gcatcatgta atgtatatgc acgtaaagaa tgtgcagatt gctgggcaag
    11461 actttattgt tctggaggat gtgcagccaa tgcatatcat gcgacaggat ctgtcaaagg
    11521 tgtatacaaa gaggggtgtg aactattctg taaacgacta gagtgtgcac ttgccgtagc
    11581 cattattcgt gatatgaaag aaaatagtca tgaagacgcc gattgttaat tttcttaaat
    11641 cgtatcaaga aaaatcacct gtaagaatgc atatgccagg ccataaaggt gctggcattc
    11701 ttggttttga aggaatggat cttacagaaa tttatggagc cgatgagttg tttgcggtag
    11761 agggaatcat taaggaaagt gaacaaaatg cttcctcttt atttggctgt ccaacctatt
    11821 attcaacgca aggctctact ttatgtattc aaacgatgtg cacgatatta tgccaagatg
    11881 ccaaaagtaa aggcaagaag cctaaaattc ttgcaggaag aaatgcccat agaagcttta
    11941 ttcatgctgc tgcactttta gattttgaga ttgaatggct atatggaaat agtgattatt
    12001 tatcttgtac gattagtaca gaaactttgg aaaaggaaat tgttgaaaac aatccaacgg
    12061 ctgtatatct gacaaatcca gactatttag gaaacctttt ggatattaaa tctctagctt
    12121 cgatatgtaa aaagcatgat gtattacttg ccatagacaa tgcccatggt gcatatcttc
    12181 gttttttaga accatcttta catcctattg atttgggagc tgatctatgt tgtgattcgg
    12241 ctcataaaac actacctgta cttacagggg gagcttattt acacttaagt gattctttga
    12301 atcaagtatg gaaaaatgac gtaaaacatt ttatggaata cttttcttcc acaagtccat
    12361 cctatttgat tatggcatct ttagatgctg caaatgaggt gttggatact acgtttaaaa
    12421 aatccttgtc tgaatgtatt caaagagttg atgtattaaa gaatgctttg attcaacatg
    12481 gatatacgat tttatctggt gaacctatga agattacgat ttcaacgaaa gagtttggct
    12541 atactggaaa tgaaatcgca aattttttaa tggaatgtga tatctatcct gaattctatg
    12601 attcagacta tattgtatta atgccatctc catataatac gaaggatgac ttaaaacgat
    12661 tagagacatg tttatgtaaa attgaacgga aatctgttgt atttaattca tttcctaaat
    12721 tagaacgtgc aagaaaagta atgagtgtac gccaagcttt atttgcgcca agtacaatga
    12781 tagaagtttc taaatcttta ggacaagtat gctccagtgt ttctgtatct tgtcctccag
    12841 cgattcttcc agtgattcca ggagaagtta tcagcaagag tgcaatagaa gtcatgaaat
    12901 attatggtat tgaaactgta cgtgttgtca aagaataaac tgattgccgg tggcaaagaa
    12961 tatccatatg atagtgtcat tatggctgtt ggatcaaagg caaacgatac aagtatgtat
    13021 gccaatctag gtattcctac atacattgtt ggtgattgta aaaaagcagg tattgcctta
    13081 gatgcattta aagatgcgta tcatgccgta ttagaaatta ataagtgaag tcttaatcgg
    13141 cttcactttt aaattggtca atatattttt gtacagaatt tgtcatttct tttgaaaaat
    13201 ccgaattgta ttttcgatta cagaaagttg ttgcccattc atttaatgtt ttatttccag
    13261 ctttatgttc aaacatattt tttaattcct gtttgtcttt tctatgatat tgatcaacac
    13321 aaattatatc ctctaattta cagcgctttg gtttttgtct tttaaaatga tcctctgcag
    13381 gatatccaag tactaacatg catacaggca ctacatattc acttagattt aataattcct
    13441 tatgtagatc atgctgctct aaaatatccc ctatgtaaca agatccaatc cctaaacttt
    13501 cggcagctac aaccgcattt tgtgcggcaa tggtcgcatc tgttgtggct agtaataaat
    13561 cgcctacgcc tggttttctt gggttgcggt tttcatattt aaataaatca taccattttt
    13621 gaaagtcggc acagaaaatt aaaatcattt tcgcttgatt gatgaagggt tgattgtcac
    13681 acgttttaga tagtgtttct tgaagctttt tgtcttgtac atcaataatt gtatacattt
    13741 gttgatttcc tgcactaggg gcttgcatag cagcttgaag tatcagtgtt ttgtcttctt
    13801 gtgatatttc tttatcttca aaaatgcgac aagacttgcg gtcaaataaa ctttgaatga
    13861 ttggattcat tataattcct tctttctttt gaaaatattt tactatagat atggtattat
    13921 ttaagtatga aacttaaaga aattaagaaa aatgcacata aaaatgtaaa aacacattat
    13981 gcgacctatt tagtgttatg tcttgcggca gtacttatgg gaagtgaatt tagttcgact
    14041 ttatctcttt taaaacaaga taatgccaag agtgtttcag gcctgttaat gcactcttct
    14101 tttgtgaagt cgatgacatc tttacttcct gaaggcgtct ttggtacgac caacggtgta
    14161 tttgcacatg tggtaaatgg aattacttca ggatcctttg tgaagacact atttttaggt
    14221 ttatcaacta ttattcattc gaaagatatt gcgagtattt gttttgtcgt aataggttta
    14281 tgcatatctg tgttctatag agtatatatt gtgaatgtat tgccggttat taatcgcaga
    14341 ctctttttgg aaggaagagt ttacgcaaaa cttccacttg atcgattggt ttatttaatg
    14401 cgaattcgaa agcagatgca tgttgcgttt gtgaaacttg ttaaatctat tattttgaca
    14461 attatgaact ttactgttgt aggaggcgtc tacttttact atgtatattt cttagtggat
    14521 tatatcttag ccgaaaatcc gacgatatct ttaaaagatg cactttcttt atctcgaaat
    14581 atgatgaagg gacataagtt tgaatgtttt aaatggcaat tttcaatggc tggatggtac
    14641 attttggatg tttgtacatt tgggattagt gctatatttt attcgaatat gtatcgtatg
    14701 tcagtaatgt gtgaatttta tacattaaga agaaaagaat ttcaaagtgc tattttaaac
    14761 gatacgtatt tatttgaaaa accaagtagt gctttgatgc gtaataccta ttcggatgta
    14821 attgcggcat tgaatgcgaa aaatccaatg gagaatgcgt atacgggtgt taaaaagttc
    14881 ttgtgtgata attttggaat tatttttcat ttgagttcta aagaaaaaca atatgaaaga
    14941 tatacctata ataaaatgga agctgaaact atgattaccg aagtgtattt attatgttat
    15001 ccagtgcgtt tatctccaat tgaagaggcg tataagaagt caaatcttcg tgttttacat
    15061 ccaaatcgaa attatacagt aacatctatt ttagtttgtt tcttctttat gtgttttgtt
    15121 ggatggatct gggaagtaag tctttcaatg attagctatg gaagatttgt gaatcgcggt
    15181 gttttacatg gtccatggat tcctatttat ggttttggct gtgttttgat tctgctttta
    15241 ttaaaacgat ttagaatgcg tccgaaagtt gaatttagta tggctgtgct tctttgtgga
    15301 tgtattgaat actttacagg tttcttttta gagcttacgc ataatggtca aaaatggtgg
    15361 gattatacgg gttatttctt aaatcttgat ggaagaattt gtgcagaagg tttattggtg
    15421 tttggcgttg gtggtatggc ttttgtctat gtgattgcac cactagttga taactgggtt
    15481 aaagaacatt taaataaaag attatctact gcctgtttag ttttacttct tttatttggt
    15541 acagatgttg tttattcgca ctttgaacct aatgtaggag aaggtgttac aggatgataa
    15601 aaaagttaaa tggaaatcaa atcaagatga ttgcgattat tgcgatgttt atggatcatt
    15661 tcgcaacgac gttgtattca aattatgaaa aattctggtg gcttttattg atacatttaa
    15721 ttggacgagt ggcagcacct attatgtggt ttatggttgt ggaaggctat acgcatacgc
    15781 atagtttaaa gaaatattta gaaagattat tgattttttc aattatcgct catttcgcgt
    15841 acaacttctg ttttggtatt tctttgattc ctttaaaaga ttctttatta aatcagacaa
    15901 gtattatatg gtcattattc ttgtctgtga ttggcttatg ggtagaagat caagaatgga
    15961 aagatgtaaa gaaaataggt tgtattctga ttctttgttt attggcattt ccaagtgatt
    16021 ggtcatgctt tccagttctt tgtacaaacc atatttataa aaatcaaggc aatctaaaaa
    16081 aacaagtatt aggtatggct ttatatattt ctatgtatgt ttttgtttat tgtctatgca
    16141 tagatgtagt ttatggttta ttacagtttg ggattgtttt agtatatcca attatgtctt
    16201 tatatgatgg aacaagagga aagagtactt ttatgaaatg gttcttctat tggttctatg
    16261 tgggacattt agttttttgt ggattgattc gtgtaatgat gtagaggtaa agaatggatg
    16321 aggagaaaag tacgtagagt gccagttgtt cttgatgcag gtgaaattaa agatttgcca
    16381 caagaagata tacggatgat tttaagaggg gccgatgaat tgatttcaac tggcggaaga
    16441 agtatgttgg ctaaaatatt aaagggttca aaggataaaa agatatttga acataaacta
    16501 aatgaatgtc ctgcttatgg atactatcag gatatgaagt tggatgatat cgcaaaatgc
    16561 attgattgga tgattaagaa agattatctc agaattgaat atgattatcg tcttccttta
    16621 ttggtatttt cagaaaaagg atggcaaatc gaaaaagaaa catttgccca agaactttat
    16681 cagagaatct gtttagatgt agaagaaaaa aaggctcgtg tcatttttga aatgaaagaa
    16741 gtgaatagac aagttgtcat gcgtgtgctt gataaaatag agaaagatgg aacaaaaaaa
    16801 tttctgcctt acttagaagc atggaaaatg ttggaagtga aaaaagttgc ggcaagaatt
    16861 atagaggttg aaaataagat agtcggaaag gatatgtaga ggttaaaatg aaaatatttt
    16921 taagcgctag gagtttgata atcttttgca cattcctcaa tcgtatttaa ataagcataa
    16981 ggcatattat atgtgagaaa tacaggcgga ttttgattat ttccatactt tgtatgcatc
    17041 aaaaatggat tcgatttcaa tggatgataa aagtttagat gaaattgtag agaagatatg
    17101 caagaaatat aaattagtct aagattgtgg tataatcttt aggcaagtaa aaacatacat
    17161 gacaggggtg caattgctga gaaaaaccct tattacctga tctggttaat tctagcgtag
    17221 ggagtcatat cgattgatag tggcactcta gggtgccttt tttattttgg aaaggaggca
    17281 atcatgaaga aaaatcgtag aattgtcatg ccgttgcttg tgtttattct agtgattggt
    17341 ggatgggaat tatatgttcg tgcatttgat atttcacttt atattttgcc tagtccatca
    17401 aaaattatca gtgcacttat tgagaatatg gatattttga tgcaacattc gcttgttaca
    17461 ttggaagaat ctgttttagg tctattgatt agtactttct ttgcgattgt gatttccatt
    17521 ggcatggatt tatccaaaac atttaagaca agtatttatc catatttgat tgtgacacaa
    17581 accgttccta ttatggtttt aggacctttg ttttcaattt ggtttggatt tgatttgttg
    17641 cctaaaatct tgattgttat atttatgtgc ttttttccta ttgcgatatc ctttacggat
    17701 gctttgtcgc aagtgagtga aaaagaaatc aatttattaa aaagttttgg tgccaatcta
    17761 tttcaaatct ataaaattgt taagattcct tctggtgcca ttggcttatt ttcaggatta
    17821 aaagtagcgg ctacttattg tgttggcgga gctattgtag gtgaatggct ttcaagtaga
    17881 gcaggacttg gctattatat gcttcgtgtg aaaaatgggt atatgttgga taaagttttt
    17941 gcgtgtgtat tgatgattat attttggagc atcctattga atttaggggt gtctttattg
    18001 gaaaagatat tgtttccaca tttacgaaaa ggagaaagaa aatgaaaatt ttaaaagcga
    18061 tgtgtgcagc tgctgttgcg ttaagcttag ttggttgtgc tcaaacatca aattcagatg
    18121 acaaattgac taaggttaca ttgatgttgg attatacgcc aaacacaaac cacactggtt
    18181 tttatgtggc aaaaaacaag gggtattata aagaagctgg tttagatgta gatattattg
    18241 aaccaggtga taatgcgaca acttctatgg ttgcagccgg aaaagctgat tttggtgttt
    18301 cttatcagga agatgttaca tatgccttga caagtgaaga tccacttcca attaaaacga
    18361 ttgcgacaat tattcaacat aatacttctg gatttgtgtc tttgaagagc gcaaacatca
    18421 attctgtaaa ggatttcgaa ggaaagacat atgcaggatg gggagcacca agtgaagaag
    18481 ctgttattaa agcggttatg aatgaagcgg gtgctgattt tagtaaatta aacattgtag
    18541 gatcagacgg atctggtatt gcaggactta gtgatgaagt aggaaagaat aaagtgaacc
    18601 taggatggga attctatggt tgggctatta ttaaagcgtt acaagatgga tatgatttaa
    18661 actatatgcc tctagctgat ttagatagcc gtttggatta ctatactcca gtaattatca
    18721 caaacaataa aatgattaaa aagaattcgg atataattca aaaatttatg gaagctacta
    18781 aaaaaggata tgaatatgcg attgatcatc caagtaaagc agctgaaatt ttacatgatg
    18841 atgctctgac agatacagat ttgaaattcc ttaaggaaag ccaaaaatac ttaagtagcc
    18901 aatatgcaaa agatgcagat tcatggggtg ttatgaaaga ttctgtatgg gataattata
    18961 cagattttat gtatgaaaca ggattgattg atcacaagat cgatgcgaaa gaccaatata
    19021 caaatgagtt tgtaaaataa tgaagctaca ggttgaaaaa ctaaatcttg aattttctgg
    19081 aaaagaaata ttgcacgata tttctttttc tattcaagaa ggagaatttg tttccattct
    19141 aggcccgagt ggttgtggaa aatctactat tttaaatata ttagccggat taattgaaga
    19201 ttattcagga cagctttttg tggatgatga acgtattaaa ggtgtcagct ctcattttgc
    19261 gtatatgcca caaaatgatt tgttgctgga atggagaacc attttagata atgtatgttt
    19321 atatggtgaa atcaatcatg ataaatctat gaaacaaaga gctttaaaag aatttgaaac
    19381 atttggcctt tctggatatg aaaatgcata tccttctagt ctttcaggag gaatgcgcca
    19441 aagggcagcc ttcttaagga cttctttatg taaagcggat attcttttat tagatgaacc
    19501 atttggagct ttggatgtca tcacgcgtaa tgatatgcaa gattggttgt tacaattaag
    19561 aaagaattat aatcgtacga ctttattagt tacacatgat attgatgaag ctttatatct
    19621 atcggatcgt attttgattt tatcgaataa gccaagtcgt attttgcagg aaattgattt
    19681 atcgaaagaa aagaaatcaa gagattggtt attttctcag agtgttttga aaaaacaggt
    19741 ctatgaatta ttaaaaggtg aaaatcatgc atgatgcaca ttatcattat tcaaaagaaa
    19801 taaatgcgct acagaatgaa tatgatattt ctgggatttg taacgtcgca aatgaaaaag
    19861 aatttgaact tgtccaacaa aagcagttgt tctattcttg tggtgtacat ccttggaatg
    19921 caagtttaga tacttttgaa tctatgcttc ctttgttaaa aaaggcaccc attatagggg
    19981 aaattggcat ggatagtgta tggtgtgatg tagatttaaa aattcaaaaa gaagtatttg
    20041 aaaaacaact tcagcttgca caagcattaa ataaacccgt tattcttcat acaaagggtc
    20101 aggaaaaaac aatacttgaa ttgattcgta aatatccaaa tacatatgtt gtacattggt
    20161 atggatgtat ggattatgtt aaagaatatg atgaggtggt atcttatttc acgattggtc
    20221 cttcaatcgg aaaagaagag gaagtaacgc atttagtaaa acaaatatct atggataaat
    20281 tacttatgga atccgatggt attgaagctg tgaaatgggc tattgatagt gacgattacc
    20341 tggctgcttt aaaaaatgaa attacgatgg tggcttcgtt aaagaatcaa tcgtattatg
    20401 aggttgaaag gattttggat cataactttt caaaattaat aaaaaaatag gagaatttct
    20461 tctcctatgc aagacagtca ttgaactgtc tttttatttg ttcttcatcc atattctttc
    20521 caataaagac caattgattg attcgatctc catactcttc atcccagttt ttggctagtt
    20581 gaggattggc ctttaataaa tctatttgat cttgttttgg tgctgatgcg atccataatg
    20641 agtcttctgt aagggatgtt aacttaccgg cttgttcaaa taagtaggca gagtcaggtt
    20701 gattatcaaa ccatacataa cctttagtac gaatgacgtt tggatagttg tttaatagat
    20761 ttgtgaattt ttttaaatcc aatggctttc ttgtttgcca tacaaaagta gaaataccat
    20821 attctaaggc ttcaccttcg tgttcatgat catgatgatg ctcgtgttct tcaatttcat
    20881 gaagccagcc aatgctattt tgagcttttt cataatcaaa gttatgtgtg tttaaaagct
    20941 cttctaaatt aacttggcca aagctagcct caatgattcc ggcatctttg cataatttat
    21001 gaatgactgc cttgatttca tttttctcat cttcattaac ggtttctgct ttgtttaaaa
    21061 ttacagtatt acagaattca agttgctgca tcaataaaga gtctaaagaa tcttcatctt
    21121 ctactggttc taataagtgt ttaccacaat tgaattcatt tgataatctt gcagcatcgg
    21181 caacacaaat aatgttatct aagtgaaata attcaggtaa tcctctagaa tatagtgttt
    21241 cattggcagc tgtgatggtt tgtgcgatag ggataggttc acaaataccg ctggcttcaa
    21301 taataatata atcaaattta ttggatgaag ctaaggctga gagttgctgc aaaagatcta
    21361 gttttagtgt gcaacaaata catccattgg taagacctac aacgtctgta tcttcttttt
    21421 gaatttgcgc attcttatca atgagttttt ggtcaacatt gatttcacca atatcattga
    21481 cgataatcgc aactttatat ccttcttgat tttttagaat gtgatttaat aaagtagttt
    21541 taccagctcc taaatagccg gttagtaata aaataggtat cgattttctt ttcattttca
    21601 aaacctcctt tacttattgt ataatattt
//
