Select genomic region:
Overview
6.1
10.1
16.1

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_ML133856.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 6.1 | NAPAA,ectoine | 177,714 | 211,682 | ectoine | Other | 75%

NZ_ML133860.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 10.1 | siderophore | 141,460 | 152,335 |

NZ_ML133866.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 16.1 | terpene | 11,462 | 26,753 | carotenoid | Terpene | 50%

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 6.1 | NAPAA,ectoine | 177,714 | 211,682 | ectoine | Other | 75%
Region 10.1 | siderophore | 141,460 | 152,335 |
Region 16.1 | terpene | 11,462 | 26,753 | carotenoid | Terpene | 50%

No secondary metabolite regions were found in these records:
  NZ_ML133851.1
  NZ_ML133852.1
  NZ_ML133853.1
  NZ_ML133854.1
  NZ_ML133855.1
  NZ_ML133857.1
  NZ_ML133858.1
  NZ_ML133859.1
  NZ_ML133861.1
  NZ_ML133862.1
  NZ_ML133863.1
  NZ_ML133864.1
  NZ_ML133865.1
  NZ_ML133867.1
  NZ_ML133868.1
  NZ_ML133869.1
  NZ_ML133870.1
  NZ_ML133871.1
  NZ_ML133872.1
  NZ_ML133873.1
  NZ_ML133874.1
  NZ_ML133875.1
  NZ_ML133876.1
  NZ_ML133877.1
  NZ_ML133878.1
  NZ_ML133879.1
  NZ_ML133880.1

Compact view
NZ_ML133856.1 - Region 1 - NAPAA,ectoine
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 177,714 - 211,682 nt. (total: 33,969 nt) Show pHMM detection rules used
NAPAA: (AMP-binding and PP-binding and TIGR02353)
ectoine: ectoine_synt

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NAPAA | ectoine | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0000853.1 |  |  | 0.86 | Other | ectoine | Streptomyces anulatus
BGC0000855.1 |  |  | 0.80 | Other | ectoine | Methylomicrobium kenyense
BGC0000859.1 |  |  | 0.80 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000856.1 |  |  | 0.80 | Other | ectoine | Methylophaga thalassica
BGC0000852.1 |  |  | 0.76 | Other | ectoine | Sporosarcina pasteurii
BGC0000858.1 |  |  | 0.63 | Other | ectoine | Methylobacter marinus
BGC0000857.1 |  |  | 0.61 | Other | ectoine | Methylophaga alcalica
BGC0000860.1 |  |  | 0.61 | Other | ectoine | Methylarcula marina
BGC0000854.1 |  |  | 0.56 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000804.1 |  |  | 0.27 | Saccharide | acarviostatin I03, acarviostatin II03, acarviostatin III03, acarviostatin IV03 | Streptomyces coelicoflavus ZG0656

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000853.1 |  | 0.74 | Other | ectoine | Streptomyces anulatus
BGC0000855.1 |  | 0.72 | Other | ectoine | Methylomicrobium kenyense
BGC0000859.1 |  | 0.72 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000856.1 |  | 0.72 | Other | ectoine | Methylophaga thalassica
BGC0000852.1 |  | 0.70 | Other | ectoine | Sporosarcina pasteurii
BGC0000858.1 |  | 0.65 | Other | ectoine | Methylobacter marinus
BGC0000857.1 |  | 0.64 | Other | ectoine | Methylophaga alcalica
BGC0000860.1 |  | 0.64 | Other | ectoine | Methylarcula marina
BGC0000854.1 |  | 0.62 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000427.1 |  | 0.53 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 177713 - 211682:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg6_200: X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (27..408): X
  NRPSPredictor2: (unknown)
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      N/A
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAESIGtVvK
    Nearest Stachelhaus code:
      lys
    Stachelhaus code match:
      80% (moderate)

NZ_ML133860.1 - Region 1 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 141,460 - 152,335 nt. (total: 10,876 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000941.1 |  | 0.33 | Other | desferrioxamin B | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001478.1 |  | 0.33 | Other | desferrioxamine E | Streptomyces sp. ID38640
BGC0001572.1 |  | 0.32 | Other | desferrioxamine E | Pantoea agglomerans
BGC0001453.1 |  | 0.30 | Other | desferrioxamine | Streptomyces argillaceus
BGC0000940.1 |  | 0.29 | Other | desferrioxamin B, desferrioxamine E | Streptomyces coelicolor A3(2)
BGC0001531.1 |  | 0.19 | Other | bisucaberin B | Tenacibaculum mesophilum
BGC0000905.1 |  | 0.17 | Other | heme D1 | Heliobacillus mobilis
BGC0001475.1 |  | 0.17 | Polyketide | aspterric acid | Aspergillus terreus NIH2624
BGC0000906.1 |  | 0.16 | Other | heme D1 | Heliophilum fasciatum
BGC0001928.1 |  | 0.15 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000941.1 |  | 0.66 | Other | desferrioxamin B | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001478.1 |  | 0.66 | Other | desferrioxamine E | Streptomyces sp. ID38640
BGC0001572.1 |  | 0.65 | Other | desferrioxamine E | Pantoea agglomerans
BGC0001453.1 |  | 0.64 | Other | desferrioxamine | Streptomyces argillaceus
BGC0000940.1 |  | 0.63 | Other | desferrioxamin B, desferrioxamine E | Streptomyces coelicolor A3(2)
BGC0001531.1 |  | 0.51 | Other | bisucaberin B | Tenacibaculum mesophilum
BGC0000905.1 |  | 0.48 | Other | heme D1 | Heliobacillus mobilis
BGC0001475.1 |  | 0.47 | Polyketide | aspterric acid | Aspergillus terreus NIH2624
BGC0000906.1 |  | 0.47 | Other | heme D1 | Heliophilum fasciatum
BGC0001928.1 |  | 0.45 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_ML133866.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 11,462 - 26,753 nt. (total: 15,292 nt) Show pHMM detection rules used
Region on contig edge.
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000637.1 |  | 0.36 | Terpene | carotenoid | Corynebacterium glutamicum
BGC0000650.1 |  | 0.28 | Terpene | carotenoid | Algoriphagus sp. KK10202C
BGC0000644.1 |  | 0.27 | Terpene | carotenoid | Dietzia sp. CQ4
BGC0000648.1 |  | 0.22 | Terpene | carotenoid | Myxococcus xanthus
BGC0001227.1 |  | 0.22 | Terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0000641.1 |  | 0.18 | Terpene | carotenoid | Enterobacteriaceae bacterium DC416
BGC0000649.1 |  | 0.18 | Terpene | carotenoid | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000664.1 |  | 0.17 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001986.1 |  | 0.17 | Other | purincyclamide | Streptomyces chrestomyceticus
BGC0000286.1 |  | 0.17 | Polyketide | viguiepinol | Streptomyces sp. KO-3988

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000637.1 |  | 0.68 | Terpene | carotenoid | Corynebacterium glutamicum
BGC0000650.1 |  | 0.61 | Terpene | carotenoid | Algoriphagus sp. KK10202C
BGC0000644.1 |  | 0.60 | Terpene | carotenoid | Dietzia sp. CQ4
BGC0000648.1 |  | 0.54 | Terpene | carotenoid | Myxococcus xanthus
BGC0001227.1 |  | 0.54 | Terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0000641.1 |  | 0.49 | Terpene | carotenoid | Enterobacteriaceae bacterium DC416
BGC0000649.1 |  | 0.49 | Terpene | carotenoid | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000664.1 |  | 0.49 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001986.1 |  | 0.48 | Other | purincyclamide | Streptomyces chrestomyceticus
BGC0000286.1 |  | 0.48 | Polyketide | viguiepinol | Streptomyces sp. KO-3988

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names