Select genomic region:
Overview
2.1
7.1
7.2

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_FCOY01000002 (original name was: NZ_FCOY01000002.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 2.1 | lassopeptide | 17,296 | 39,718 |

NZ_FCOY01000007 (original name was: NZ_FCOY01000007.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 7.1 | arylpolyene | 884,944 | 926,134 | xanthomonadin I | Other | 57%
Region 7.2 | RiPP-like | 1,003,138 | 1,013,962 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 2.1 | lassopeptide | 17,296 | 39,718 |
Region 7.1 | arylpolyene | 884,944 | 926,134 | xanthomonadin I | Other | 57%
Region 7.2 | RiPP-like | 1,003,138 | 1,013,962 |

No secondary metabolite regions were found in these records:
  NZ_FCOY01000001 (original name was: NZ_FCOY01000001.1)
  NZ_FCOY01000003 (original name was: NZ_FCOY01000003.1)
  NZ_FCOY01000004 (original name was: NZ_FCOY01000004.1)
  NZ_FCOY01000005 (original name was: NZ_FCOY01000005.1)
  NZ_FCOY01000006 (original name was: NZ_FCOY01000006.1)

Compact view
c00002_NZ_FCOY.. - Region 1 - lassopeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 17,296 - 39,718 nt. (total: 22,423 nt) Show pHMM detection rules used
lassopeptide: (PF13471 and Asn_synthase or micJ25 or mcjC)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Lasso peptides
Pfam domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lassopeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000580.1 |  | 0.32 | RiPP | xanthomonin I, xanthomonin II | Xanthomonas gardneri ATCC 19865
BGC0000576.1 |  | 0.32 | RiPP | rubrivinodin | Rubrivivax gelatinosus IL144
BGC0000577.1 |  | 0.31 | RiPP | sphingonodin II | Sphingobium japonicum UT26S
BGC0000570.1 |  | 0.31 | RiPP | astexin-1 | Asticcacaulis excentricus CB 48
BGC0001786.1 |  | 0.28 | RiPP | subterisin | Novosphingobium subterraneum
BGC0000573.1 |  | 0.28 | RiPP | caulonodin I, caulonodin II | Caulobacter sp. K31
BGC0001184.1 |  | 0.22 | Other | bacilysin | Bacillus velezensis FZB42
BGC0000888.1 |  | 0.22 | Other | bacilysin | Bacillus sp. CS93
BGC0000574.1 |  | 0.18 | RiPP | caulosegnin I, caulosegnin II, caulosegnin III | Caulobacter segnis ATCC 21756
BGC0001140.1 |  | 0.16 | Terpene | platensimycin, platencin | Streptomyces platensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000580.1 |  | 0.65 | RiPP | xanthomonin I, xanthomonin II | Xanthomonas gardneri ATCC 19865
BGC0000576.1 |  | 0.65 | RiPP | rubrivinodin | Rubrivivax gelatinosus IL144
BGC0000577.1 |  | 0.65 | RiPP | sphingonodin II | Sphingobium japonicum UT26S
BGC0000570.1 |  | 0.65 | RiPP | astexin-1 | Asticcacaulis excentricus CB 48
BGC0001786.1 |  | 0.62 | RiPP | subterisin | Novosphingobium subterraneum
BGC0000573.1 |  | 0.61 | RiPP | caulonodin I, caulonodin II | Caulobacter sp. K31
BGC0001184.1 |  | 0.55 | Other | bacilysin | Bacillus velezensis FZB42
BGC0000888.1 |  | 0.55 | Other | bacilysin | Bacillus sp. CS93
BGC0000574.1 |  | 0.50 | RiPP | caulosegnin I, caulosegnin II, caulosegnin III | Caulobacter segnis ATCC 21756
BGC0001140.1 |  | 0.46 | Terpene | platensimycin, platencin | Streptomyces platensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Lasso peptide predictions
Lists the possible core peptides for each biosynthetic enzyme, including the predicted class. Each core peptide shows the leader and core peptide sequences, separated by a dash.

#### Lassopeptide(s) for ctg2_28 - Putative Class II

ctg2_28 leader / core peptide / cleaved tail
  MDTKQNTRTNTAEDLIVLGVASVETK - GGAGFGEPTGPGLPMIPG - ISEE

#### Legend:

Red: Putative macrolactam
Purple: Putative cleaved off residues
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Lasso peptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of disulfide bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

ctg2_28 - Class II
  Cleavage pHMM score: 14.00
  RODEO score: 25
  Monoisotopic mass: 1592.8 Da
  Molecular weight: 1593.8 Da
  Number of bridges: 0

Weights before cleavage:
  Monoisotopic mass: 2051.0 Da
  Molecular weight: 2052.3 Da

c00007_NZ_FCOY.. - Region 1 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 884,944 - 926,134 nt. (total: 41,191 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000783.1 |  | 0.34 | Saccharide | O-antigen | Xanthomonas oryzae pv. oryzae
BGC0001538.1 |  | 0.29 | NRP, Polyketide | caboxamycin | Streptomyces sp. NTK 937
BGC0000888.1 |  | 0.29 | Other | bacilysin | Bacillus sp. CS93
BGC0001444.1 |  | 0.27 | Other | caboxamycin | Streptomyces sp. NTK 937
BGC0001197.1 |  | 0.24 | Polyketide | frankiamicin | Frankia sp. EAN1pec
BGC0000228.1 |  | 0.23 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0001723.1 |  | 0.22 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0000840.1 |  | 0.22 | Other | xanthomonadin I | Xanthomonas oryzae pv. oryzae
BGC0001895.1 |  | 0.21 | Polyketide | huanglongmycin A, huanglongmycin B, huanglongmycin C | Streptomyces sp. CB09001
BGC0001343.1 |  | 0.21 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000783.1 |  | 0.67 | Saccharide | O-antigen | Xanthomonas oryzae pv. oryzae
BGC0001538.1 |  | 0.63 | NRP, Polyketide | caboxamycin | Streptomyces sp. NTK 937
BGC0000888.1 |  | 0.62 | Other | bacilysin | Bacillus sp. CS93
BGC0001444.1 |  | 0.61 | Other | caboxamycin | Streptomyces sp. NTK 937
BGC0001197.1 |  | 0.57 | Polyketide | frankiamicin | Frankia sp. EAN1pec
BGC0000228.1 |  | 0.57 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0001723.1 |  | 0.55 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0000840.1 |  | 0.55 | Other | xanthomonadin I | Xanthomonas oryzae pv. oryzae
BGC0001895.1 |  | 0.54 | Polyketide | huanglongmycin A, huanglongmycin B, huanglongmycin C | Streptomyces sp. CB09001
BGC0001343.1 |  | 0.54 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00007_NZ_FCOY.. - Region 2 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,003,138 - 1,013,962 nt. (total: 10,825 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001882.1 |  | 0.19 | Polyketide | chrysoxanthone A, chrysoxanthone B, chrysoxanthone C | Penicillium rubens Wisconsin 54-1255
BGC0000573.1 |  | 0.12 | RiPP | caulonodin I, caulonodin II | Caulobacter sp. K31
BGC0001556.1 |  | 0.09 | NRP, Polyketide | combamide | Streptomyces sp.
BGC0000221.1 |  | 0.07 | Polyketide | erdacin | uncultured soil bacterium V167
BGC0000274.1 |  | 0.07 | Polyketide | tetarimycin A, tetarimycin B | uncultured bacterium
BGC0000279.1 |  | 0.06 | Polyketide | xantholipin | Streptomyces flavogriseus
BGC0000966.1 |  | 0.05 | NRP, Polyketide | caerulomycin A | Actinoalloteichus sp. WH1-2216-6
BGC0001568.1 |  | 0.05 | Polyketide | cytorhodin | Streptomyces sp. SCSIO 1666
BGC0001074.1 |  | 0.05 | Saccharide, Polyketide | cosmomycin D | Streptomyces olindensis
BGC0001956.1 |  | 0.05 | Polyketide | miharamycin A, miharamycin B | Streptomyces miharaensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001882.1 |  | 0.51 | Polyketide | chrysoxanthone A, chrysoxanthone B, chrysoxanthone C | Penicillium rubens Wisconsin 54-1255
BGC0000573.1 |  | 0.40 | RiPP | caulonodin I, caulonodin II | Caulobacter sp. K31
BGC0001556.1 |  | 0.34 | NRP, Polyketide | combamide | Streptomyces sp.
BGC0000221.1 |  | 0.29 | Polyketide | erdacin | uncultured soil bacterium V167
BGC0000274.1 |  | 0.27 | Polyketide | tetarimycin A, tetarimycin B | uncultured bacterium
BGC0000279.1 |  | 0.25 | Polyketide | xantholipin | Streptomyces flavogriseus
BGC0000966.1 |  | 0.22 | NRP, Polyketide | caerulomycin A | Actinoalloteichus sp. WH1-2216-6
BGC0001568.1 |  | 0.22 | Polyketide | cytorhodin | Streptomyces sp. SCSIO 1666
BGC0001074.1 |  | 0.21 | Saccharide, Polyketide | cosmomycin D | Streptomyces olindensis
BGC0001956.1 |  | 0.21 | Polyketide | miharamycin A, miharamycin B | Streptomyces miharaensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names