LOCUS       NZ_CP072387.1          10297 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP072387.1 Cellulosimicrobium cellulans strain ORNL-0100
            chromosome, complete genome.
ACCESSION   NZ_CP072387
VERSION     NZ_CP072387.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:25:24
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3967133
            Orig. end    :: 3977430
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10297
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[3972133:3972430](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5297)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10297
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10297
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="5"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(1593..2660)
                     /locus_tag="ctg1_3518"
                     /transl_table=11
                     /translation="MRLRSVLREAWRNASTGTARCVTLALVLMVLVLTTLGAEISTVAA
                     AERQATEFRAAGASILTISAPGRVDAARCESLRDLPGVHTAGALTVRPDESVAAVALTG
                     APMPAADASPGFPAVVGATTDGGPGLILTDDAAATLGLGLGDRLSATTGSSRLAGTYTY
                     PRDGRRDGYGYLAVSVTGYRAPFDECWVEAWPMTTDLNPLLFTVLRPGGGVDDVPQVQQ
                     LNSTLGSGLDGSGLFHERVTRFGGLLVGLVAVVVAFVAVRARRVELATALHDGMRRRDL
                     WTIVLLESALWAAPAVAVGTAFSLTWFGRDGDLLVGTVLGARVVLSVLAGSAAGVAVAL
                     ATTHEKDLFAYAKNR"
     CDS             complement(2657..3265)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 156.6; E-value:
                     1.4e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_3519"
                     /transl_table=11
                     /translation="VRVTVSGLGHRFPGRPWLFRGLDLDLRPGHAYALTGPSGSGKSTL
                     LGLLAGWEAPSEGVVAREGVGRTGWVFQNPHGTPRRSAHDHVALPLLVRGLHPREADRR
                     AADLLGRFGLGGVAQQQFRRLSGGEAQRLMLARAIASEPGLLLVDEPTAQLDLPTARTV
                     NESLDALRSPGTIIVVATHDAATRDACSNHVDLTLHAAA"
     PFAM_domain     complement(2807..3205)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3519_0120"
                     /evalue="2.10E-24"
                     /label="ctg1_3519"
                     /locus_tag="ctg1_3519"
                     /protein_end="153"
                     /protein_start="20"
                     /score="86.7"
                     /tool="antismash"
                     /translation="GLDLDLRPGHAYALTGPSGSGKSTLLGLLAGWEAPSEGVVAREGV
                     GRTGWVFQNPHGTPRRSAHDHVALPLLVRGLHPREADRRAADLLGRFGLGGVAQQQFRR
                     LSGGEAQRLMLARAIASEPGLLLVDEPTA"
     CDS             complement(3256..4251)
                     /locus_tag="ctg1_3520"
                     /transl_table=11
                     /translation="VLGGLTLVAVGIALGAAWASPAVPAALRPPAPLTTFTVQAATFDD
                     VRSVRLAVARGEESGLVSPGSGLVTRFDCRPGSAIESGTAPLWLDDAPIVALATTLPLW
                     RDLPVGAEGNDVRALQEELTRLGHPVEITGTLGRKTLRAVNTLLDDLGAPSALTSVPRS
                     RILWIPGPSVTLSECSATIGSRLEAGAELAVTPGTLAEVTLRDGAPSDLVAGARTLRVD
                     GIDVAVEPQAPVTDPSLLARLDAAPSLQQGGTGDEAPVGQLRLSEPVDVSVVPPSAVIT
                     APDGTSCVTTGAVPHAVRVVGSELGQTFVLFDGIPPTVVETSPRQDTPCA"
     CDS             complement(4280..4906)
                     /locus_tag="ctg1_3521"
                     /transl_table=11
                     /translation="MSRCKAPRLFAAAALAAFSPLLVACGTSQSAGSSAAEGAGAEVPL
                     FDGPYAAEFAAFYADAESEFARQAIADEEITDAEYAEMEEKFRTCLDGEGVTFSGFEPD
                     GSYEASHLPDGGDPYEVVKVCERESGADTVGALHDIMASNPANLDVPTIMAECLVGKGV
                     VPAAYSADDYVTDTEGRFSDLAALTTELRDALMTCSDDPLGLAGG"
     CDS             complement(5001..5297)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Lactococcin_972"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3522"
                     /sec_met_domain="Lactococcin_972 (E-value: 3.6e-09,
                     bitscore: 34.9, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRKIMTAVITATLVAGVALGAAGPASAAISYPSVGGTWDHGADAK
                     DVWSLYHHGSRVHKASTYEDNGLRSSGWVAAGLWARQWDAVRLFGNKAYYDVK"
     PFAM_domain     complement(5013..5195)
                     /aSDomain="Lactococcin_972"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09683.12"
                     /description="Bacteriocin (Lactococcin_972)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3522_0121"
                     /evalue="4.00E-10"
                     /label="ctg1_3522"
                     /locus_tag="ctg1_3522"
                     /protein_end="95"
                     /protein_start="34"
                     /score="40.2"
                     /tool="antismash"
                     /translation="GGTWDHGADAKDVWSLYHHGSRVHKASTYEDNGLRSSGWVAAGLW
                     ARQWDAVRLFGNKAYY"
     CDS             complement(5471..6361)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3523"
                     /sec_met_domain="APH (E-value: 8.3e-34, bitscore: 115.4,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAPETAITADLVREALAEQHPDLAGLPLREVAGGWGNQMWRLGD
                     DLAVRVQRMDPTPELQLKERRWLPALAPRLPLPVPTPVRHGEPGARLPRHWTVMTWIPG
                     EPLDHGTITRGEHAADALAGFLRALHVAAPADAPSSTDRGAHPRDVTDGFEGFLRAVAP
                     ADSAAVRSVWADAVAAPAWEGPPVWVHGDLHPANVVVADGTLAGVVDFGDLFAGDPAWD
                     LAAAWVLLPAGLAARFFDAYAPADDATVRRARGLAALKALFLLLMGQNGDRGLPGGKAH
                     WGPVGRAALDRVLAG"
     PFAM_domain     complement(5624..6277)
                     /aSDomain="APH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01636.25"
                     /description="Phosphotransferase enzyme family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3523_0122"
                     /evalue="2.70E-32"
                     /label="ctg1_3523"
                     /locus_tag="ctg1_3523"
                     /protein_end="246"
                     /protein_start="28"
                     /score="112.6"
                     /tool="antismash"
                     /translation="LREVAGGWGNQMWRLGDDLAVRVQRMDPTPELQLKERRWLPALAP
                     RLPLPVPTPVRHGEPGARLPRHWTVMTWIPGEPLDHGTITRGEHAADALAGFLRALHVA
                     APADAPSSTDRGAHPRDVTDGFEGFLRAVAPADSAAVRSVWADAVAAPAWEGPPVWVHG
                     DLHPANVVVADGTLAGVVDFGDLFAGDPAWDLAAAWVLLPAGLAARFFDAYAPAD"
     CDS             complement(6398..6685)
                     /locus_tag="ctg1_3524"
                     /transl_table=11
                     /translation="VPSYRVTLAVGLLRPGADPEAVLPAAADAARALTTVEAYDVGVVR
                     GEARVTVRFLADTDASAHGVADAVEAGVRAHAATSGGRLTRRWGARWHPA"
     CDS             complement(6689..7321)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248:methyltransferase (Score: 73.6; E-value:
                     2.9e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3525"
                     /transl_table=11
                     /translation="MSATRPSRWEQKTAADPSHSTWYVERFRAMAARGADLAGEARLVD
                     AMLPRGSRVLDAGCGPGRVGAELFARGHAVVGVDVDPVLIDAARTDHPGPDWRVGDLAE
                     LDLPAEGVTEPFDLIVCAGNVVTFLAPGTEVEVLRRFRAHLAPGGRAVVGFGTGRGYPP
                     EQFLADATEAGLHLDLALATWDLRPWTPDADFLVAVLSDAAPRPGVA"
     PFAM_domain     complement(6863..7159)
                     /aSDomain="Methyltransf_11"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08241.14"
                     /description="Methyltransferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3525_0123"
                     /evalue="8.30E-11"
                     /label="ctg1_3525"
                     /locus_tag="ctg1_3525"
                     /protein_end="153"
                     /protein_start="54"
                     /score="42.5"
                     /tool="antismash"
                     /translation="LDAGCGPGRVGAELFARGHAVVGVDVDPVLIDAARTDHPGPDWRV
                     GDLAELDLPAEGVTEPFDLIVCAGNVVTFLAPGTEVEVLRRFRAHLAPGGRAVV"
     CDS             7359..8882
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1210:glycerol kinase (Score: 322.3; E-value: 7.9e-98)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3526"
                     /transl_table=11
                     /translation="VTLVPTTLGTTLGIDLGTSGLKLVLLGRDGSVVAEAEAAYDVEHP
                     RPGRSESAPTTWTTALGAALDDLAAHAAGLGEVAVRAVGVAGQMHAAVLVDAAGDAVVP
                     AVLWTDARAADRLDRWRALPDAVRAPLANPLVPGMTGPVLDWFAAHDRATLDRAAHVLL
                     PKDVVRAWLVDDLALPVATTDRSDAAGTLLWDVPRDAWAADVVAHLDLPARLLPGVAPS
                     DAVAGTTARLARWLPASGSAVPVVVGGGDTPAARLAVGAPGLHVNLGTGAQVMAALDRP
                     EPVLDPLVHTFADTGAGSAARWYRLAAVQNAGLALGWALRVLGLGWSDGLALARTVPDG
                     AGGVTFLPFLTGERGGVAGPDARGAWTGLREDTGRPELVRAAVEGMVFAVAAAVDLLDA
                     APAAPVVAPVAGAPGSRPDGEPGAVVVTGGGSRDPLVRRLLADALGRPVHRVGLRSATA
                     VGAALLAARGTGDPVEPVVDTDEPELPGPGRADVVGHLARWREAAAALA"
     PFAM_domain     7389..8129
                     /aSDomain="FGGY_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00370.23"
                     /description="FGGY family of carbohydrate kinases,
                     N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3526_0124"
                     /evalue="2.10E-40"
                     /label="ctg1_3526"
                     /locus_tag="ctg1_3526"
                     /protein_end="257"
                     /protein_start="10"
                     /score="139.0"
                     /tool="antismash"
                     /translation="TLGIDLGTSGLKLVLLGRDGSVVAEAEAAYDVEHPRPGRSESAPT
                     TWTTALGAALDDLAAHAAGLGEVAVRAVGVAGQMHAAVLVDAAGDAVVPAVLWTDARAA
                     DRLDRWRALPDAVRAPLANPLVPGMTGPVLDWFAAHDRATLDRAAHVLLPKDVVRAWLV
                     DDLALPVATTDRSDAAGTLLWDVPRDAWAADVVAHLDLPARLLPGVAPSDAVAGTTARL
                     ARWLPASGSAVPVVVGGGDTPAARL"
     PFAM_domain     8154..8759
                     /aSDomain="FGGY_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02782.18"
                     /description="FGGY family of carbohydrate kinases,
                     C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3526_0125"
                     /evalue="8.80E-28"
                     /label="ctg1_3526"
                     /locus_tag="ctg1_3526"
                     /protein_end="467"
                     /protein_start="265"
                     /score="97.5"
                     /tool="antismash"
                     /translation="VNLGTGAQVMAALDRPEPVLDPLVHTFADTGAGSAARWYRLAAVQ
                     NAGLALGWALRVLGLGWSDGLALARTVPDGAGGVTFLPFLTGERGGVAGPDARGAWTGL
                     REDTGRPELVRAAVEGMVFAVAAAVDLLDAAPAAPVVAPVAGAPGSRPDGEPGAVVVTG
                     GGSRDPLVRRLLADALGRPVHRVGLRSATAVGAALLAAR"
     CDS             8916..9656
                     /locus_tag="ctg1_3527"
                     /transl_table=11
                     /translation="MSTAAAVTTGTAPVTDLASSAPTGEILAVCRVHALLPDAGPVGVT
                     AIDKRPVTGPVKVRRLGLYADLQADRANHGGEEQAVYAYGQDDADWWAGELGRDVPPGL
                     FGENLRVEGIPVTEAVVGERWAVGTALLEVTQPRTPCSTFARRLGEDRWVKRFTVANRT
                     GAYLRVVQHGELRAGDAVTVCYRPEHGVTLADWFGAWNGRGADPERAAGLARRLLAAHL
                     EGDVTLTDELRARAEIAAGRRIED"
     PFAM_domain     9123..9461
                     /aSDomain="MOSC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03473.19"
                     /description="MOSC domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3527_0126"
                     /evalue="1.70E-24"
                     /label="ctg1_3527"
                     /locus_tag="ctg1_3527"
                     /protein_end="182"
                     /protein_start="69"
                     /score="86.5"
                     /tool="antismash"
                     /translation="DRANHGGEEQAVYAYGQDDADWWAGELGRDVPPGLFGENLRVEGI
                     PVTEAVVGERWAVGTALLEVTQPRTPCSTFARRLGEDRWVKRFTVANRTGAYLRVVQHG
                     ELRAGDAVT"
     CDS             complement(9660..10226)
                     /locus_tag="ctg1_3528"
                     /transl_table=11
                     /translation="MLPMGLSEKHLTEGEHVVMELKEHAKALFWPFVLLLVLVAAVVVT
                     VLLVPNDVVRWVVAGLALVAAVVWVFVPWLRWRTTEYTVTNKRIAMRSGIITRTGRDIP
                     LYRINDVNYEKGPIDRIFGCGTLVISDATDKPGLNLHDVPDVENVQVRLHDLLFTADDG
                     SDDGEWPPNEPPRGRRGPRIPRAER"
     PFAM_domain     complement(9777..9998)
                     /aSDomain="bPH_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03703.16"
                     /description="Bacterial PH domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3528_0127"
                     /evalue="1.80E-21"
                     /label="ctg1_3528"
                     /locus_tag="ctg1_3528"
                     /protein_end="150"
                     /protein_start="76"
                     /score="76.2"
                     /tool="antismash"
                     /translation="WRTTEYTVTNKRIAMRSGIITRTGRDIPLYRINDVNYEKGPIDRI
                     FGCGTLVISDATDKPGLNLHDVPDVENVQ"
ORIGIN
        1 cacgcccacg acggcgacgt cccgcacgcc gggcatcccg cgcaggtgct cctcgacctg
       61 cgacgggtac accttgaacc cgccggtgac gatcatctcc ttgatgcggt cgacgagcgt
      121 gacgaggccc gcgtcggggc cgtcgagggc cacgcgcacg acgtcgcccg tgcggagcca
      181 cccgtcgtcg agcagctggt gggcggtctc ctcgggacgg ttccagtagc cgcggaacac
      241 ctgcgggccg cgcacgagca gctcgccgcg cacggtgcgc acgccgtcgt cggacggccc
      301 ggacggctcg gcgtcgcgca ggtcgccggc gtcgagcgcg tcggcgtcga cgacgcggat
      361 ctcggtgctg gggaacggga gcccgagggt gccggggcgg cggtcgtcgg agcacgggtt
      421 gccgagcgag atcggtgacg tctcggtcat gccgtagccc tcgatgagca ggccgcccgt
      481 cgcgtcctcc cagcgctgcg ccgtctccgc ggtgatgggc atcgcgccgg cgaaggccag
      541 gcggatcgag gtgaggtcgg agcctgcgcc cggggcgtcg gccgcggcgg tgacgatgcg
      601 gtcgaacatg ggcgcgacgc cgggcaggaa cgtcgcgggc cgccgcgcct gggcggcgac
      661 gaacgcctgc gggtcgaact tggggaacgc gacgagggtc gcgccgacgc gcgcgggcag
      721 ggtgaggcag aacgtcaggc cgaacgcgtg gaagaagggc agcacgccgt agacggtctc
      781 ggcgccctcc tcgaacgacg cccacgcctg gccctggacc acgttggcga cgaggttgcg
      841 gtgcgtgagg accgcgccct tcggggtgcc ggtcgtgccg cccgtgtact gcaggagagc
      901 gacgtcgtcg gcggcggggt gcggcagcgc cggggggagg gcccgcgcgc gccggacgag
      961 gtcgtgccag tcgggcaccc cggccgggag tggcgtgcgc agggcctcgc gctgcgcacg
     1021 ggcccgggcg acgggcaggc gcagcgcgag gcggctgccg cgcggcaggt cgcgcgcgat
     1081 gtcgagcccg acgacgcgcc gcagcccggg cacgtgggcg cgggcctcga gcacggccgg
     1141 gaccgtcttg gtccacacga ccgcgacgct cgcgccggag tcggcgagct ggtgggcgag
     1201 ctcgtcggcc gtgtacgtcg ggttgtgctc gaccacgacg gcgcccagcc gctcgaccgc
     1261 gtagaacgcg acgacgtgcg acgtcgcgtt gggcagcacg agcgcgacgc ggtcgccgcg
     1321 ccggacgccg aggtcgtgca gggcgctcgc ggcgcgctcg acctgcgcca cgagctgcgc
     1381 gtacgtggtg gtcgcgccga agaagtcgac cgcgacgcgg tccggccagc gctcggccgc
     1441 gcggtagagg gcggccgtga ccggctcgtc ggggacctcg acgtccgtcg ggacgccggg
     1501 ggcgtaacgg tcggtccacg gcctcgtcgc cagagtgttc actacgccac cgtaacctac
     1561 ggttgcgtag gttgtgtgcg gcagcggtgt tgtcatcggt tcttcgcgta ggcgaacagg
     1621 tctttctcgt gcgtcgtcgc cagggcgacg gcgacgcctg ccgcgctacc tgccagcacg
     1681 gacaggacca cgcgcgcacc gaggaccgtg ccgaccagca ggtcaccgtc ccggccgaac
     1741 cacgtgagcg agaacgccgt cccgaccgct accgccggag cggcccacag agccgactcc
     1801 agcagcacga tcgtccacag gtcacgtcgt cgcatcccgt cgtgaagggc cgtggcgagc
     1861 tccactcggc gagcgcgcac ggcgacgaag gcgacgacga cggcgaccag cccgacgagg
     1921 agcccgccga accgggtgac gcgctcgtgg aacagcccag agccgtcgag ccccgaaccc
     1981 agcgtggagt tgagctgctg cacctggggg acgtcgtcga cgccaccacc cggccggagc
     2041 acggtgaaga gcagcgggtt caggtccgtg gtcatcggcc acgcctcgac ccagcactcg
     2101 tcgaacggtg cgcggtaccc ggtgacgctc accgccagat agccgtaccc gtcccgccgg
     2161 ccgtcgcggg ggtaggtgta ggtgcccgcg aggcgagacg acccggtcgt cgcggagagc
     2221 cggtcgccga gcccgaggcc gagcgtcgcg gcggcgtcgt cggtcaggat cagacccggc
     2281 cccccgtcgg tcgtggcacc gacgacggca gggaaccccg ggctcgcgtc cgcggcaggc
     2341 atgggggcgc cggtaagggc gacggcggcg acggactcgt ccggtcggac ggtgagcgca
     2401 cccgccgtgt gcactccggg cagatcgcgc aacgactcgc accgcgcggc gtcgacccgg
     2461 cccggtgccg agatcgtgag aatcgacgca ccagcggcgc ggaactccgt ggcctgcctc
     2521 tcggccgcgg ccacggtcga gatctcagct cccagcgtgg tgaggaccag gaccatcagc
     2581 accagtgcca gcgtgacgca gcgtgccgta cctgtggaag cgttgcgcca cgcctcgcgg
     2641 aggaccgagc gcagtctcat gcggcggcgt gcagcgtcag gtcgacgtga ttcgagcacg
     2701 cgtcacgggt cgcggcgtcg tgcgtcgcga cgacgatgat cgtcccgggt gagcgcagcg
     2761 catcgagcga ctcgttgacg gtgcgggcgg tcggcaggtc gagctgggcg gtcggctcgt
     2821 ccacgaggag gagccctggt tccgatgcga tcgctcgcgc cagcatcagg cgctgcgcct
     2881 ccccacccga gaggcgtcgg aactgctgct gcgcgacacc accgagcccg aacctgccga
     2941 ggaggtcagc ggctcgccga tccgcctccc gggggtgcag cccccgcacg agcagcggga
     3001 gcgcgacgtg gtcgtgtgct gagcgccgcg gcgtcccgtg cgggttctgg aacacccacc
     3061 cggtgcgccc gacgccctct cgcgcgacaa cgccctcgct gggcgcctcc cacccggcga
     3121 gcaggccgag gagggtgctc ttgcccgacc ccgacgggcc ggtcagcgcg taggcgtgtc
     3181 ccggccgcag gtcgaggtcg agcccgcgga atagccacgg tcgcccgggg aagcggtgcc
     3241 cgaggccgga gacggtcacg cgcacggggt gtcctgtcgg ggcgacgtct cgacgacggt
     3301 cggcgggatg ccgtcgaaca gcacgaacgt ctggccgagc tcggatccca cgacccgcac
     3361 cgcgtgcggg acggcgcctg tggtcacgca gctggtcccg tccggtgcgg tgatcaccgc
     3421 tgacggtggg acgaccgaca cgtccaccgg ttctgacaac cgcagttggc cgaccggggc
     3481 ctcgtcgccc gtacctcctt gctggagcga gggcgcagcg tcgagccgtg cgagcagcga
     3541 tgggtcggtg acgggggcct gcggctcgac cgcgacgtcg atcccgtcca cgcggagcgt
     3601 gcgcgcgccg gcgacgaggt cggacggcgc accgtcgcgc agcgtgactt cggccagcgt
     3661 gccgggcgtg acggcgagct ctgctccggc ttcgagtcgg ctccctatcg tggccgagca
     3721 ctccgagagg gtgaccgacg gtccggggat ccacaggatg cgggatcgcg ggacggaggt
     3781 gagtgccgag ggggcaccga ggtcgtcgag gagcgtgttg accgcccgga gcgtcttcct
     3841 gccgagcgtc ccggtgatct ccacggggtg ccccaggcgc gtcagctcct cctgcagcgc
     3901 ccgcacgtcg ttgccctcgg cgccgaccgg aaggtcccgc cagaggggga gcgtcgtcgc
     3961 gagcgcgacg atcggcgcgt cgtcgagcca gagcggcgcg gtcccggact cgatggccga
     4021 gccgggacgg cagtcgaagc gtgtgacgag accgctaccg ggcgatacca gccctgactc
     4081 ctcgccgcgg gcgacggcga gccgcacgga gcggacgtcg tcgaacgtgg ctgcctggac
     4141 ggtgaaggtg gtgaggggag cgggcggtcg cagggccgca gggacggccg gggaggccca
     4201 cgcggcaccg agggcgatcc cgacggcgac gagagtcagc cccccgagca cccacagtcc
     4261 ggccttcgca gggctgcgct cagccaccgg ccaggcccag ggggtcgtcc gagcacgtca
     4321 tcagggcgtc ccggagctcg gtcgtgagag cagcgaggtc ggagaagcgg ccctccgtgt
     4381 ccgtgacata gtcgtctgcg gagtaggcgg cagggacgac ccccttgccg acgaggcact
     4441 ccgccatgat ggtcgggacg tcgaggttgg ccgggttcga cgccatgatg tcgtgcagcg
     4501 ccccgaccgt gtctgccccc gactcgcgct cgcacacctt caccacttcg tagggatcgc
     4561 ctccgtccgg caggtgtgag gcctcatacg agccgtcggg ctcgaagccc gagaacgtca
     4621 cgccctcgcc gtcgaggcac gtacggaact tctcctccat ctcggcgtac tcggcgtcgg
     4681 tgatctcctc gtcggcgatc gcctggcggg cgaactcgga ctcagcgtcg gcgtagaacg
     4741 cggcgaactc ggcggcgtag ggcccgtcga acaggggaac ctccgccccc gcaccctcgg
     4801 ccgcgctcga ccccgcggac tgcgaggtgc cgcacgcgac gaggaggggc gagaacgcgg
     4861 cgagtgctgc cgcggcgaag agccgcggcg ccttgcatcg agacatgatt ctccggtggc
     4921 tgggcgttcg tcgggatcga gcggacccgc gctccgccgg tcgtcgcgtc agcgtgacga
     4981 ccggcagcgc gcgagctgtt ctacttgacg tcgtagtacg ccttgttccc gaacaagcgg
     5041 accgcgtccc actgtctcgc ccacagtccc gcggcaaccc agccgctgct ccggaggccg
     5101 ttgtcctcgt acgtcgaggc cttgtggacc ctggagccgt ggtggtagag cgaccagacg
     5161 tccttggcgt cggcgccgtg gtcccacgtg ccgcccacgg acgggtagct gatcgccgcg
     5221 ctggcagggc cagcggctcc gagcgcgaca ccagcgacga gcgtggcggt gatgaccgcc
     5281 gtcatgatct ttcgcacgag attccccctt gaagcgatga ccgtccgagg gagtatggtg
     5341 cggatggcag gagtggtgag atatgtccgt tatatggacg agcggaggtg gtcaccacgg
     5401 gaggtcgcca tcttgccgag cgtgcggcgc ggctcgctcc gaccgaagcc ctggcacctc
     5461 cggtgacgcg tcagcccgcc aggacgcggt cgagcgccgc gcgccccacg ggaccccagt
     5521 gggccttgcc gccgggcagt ccgcggtcgc cgttctgccc catgagcagg aggaagaggg
     5581 ccttgagcgc cgcgagcccg cgggcacgcc ggaccgtcgc gtcgtcggcc ggcgcgtagg
     5641 cgtcgaagaa ccgcgccgcg aggccggcgg gcagcagcac ccaggcggcg gcgaggtccc
     5701 aggccgggtc gcccgcgaac aggtcgccga agtcgacgac gcccgcgagc gtcccgtccg
     5761 cgacgacgac gttcgcgggg tgcaggtccc cgtgcaccca cacgggcgga ccctcccacg
     5821 cgggggcagc gacggcgtcg gcccagacgg accggacggc ggcggagtcc gcgggggcga
     5881 cggcgcgcag gaagccctcg aagccgtccg tgacgtcgcg ggggtgggcg ccccggtccg
     5941 tggacgacgg cgcgtcggcg ggtgccgcga cgtgcagcgc ccggaggaag cccgccagcg
     6001 cgtcggcggc gtgctcgccc cgggtgatcg tcccgtggtc cagcggctcg ccggggatcc
     6061 aggtcatgac cgtccagtgc cgcgggagac gcgcgcccgg ctcgccgtgc cgcaccggcg
     6121 tcggcacggg gagcggcagc cgcggcgcga gcgcgggcag ccaccgccgt tccttgagct
     6181 ggagctccgg cgtcgggtcc atgcgctgca cccgcacggc caggtcgtcg ccgagccgcc
     6241 acatctggtt cccccagccg cccgcgacct cgcggagcgg cagcccggcg aggtcggggt
     6301 gctgctccgc gagggcctcg cggacgaggt cggcggtgat cgcggtctcg ggggcgctca
     6361 tgcgcgccca cggtaccgac gcgccgtcgg ccgctgctca ggcggggtgc cagcgcgctc
     6421 cccagcggcg ggtcaggcgt ccgcccgacg tcgccgcgtg ggcccgcacg cccgcctcca
     6481 cggcgtccgc gacgccgtgc gcggacgcgt ccgtgtcggc gaggaagcgc acggtgacgc
     6541 gcgcctcgcc acggacgacg ccgacgtcgt acgcctcgac ggtcgtgagg gcgcgcgccg
     6601 cgtcggcggc cgcgggcagc acggcctcgg ggtcggcgcc cgggcgcagg agtccgacgg
     6661 cgagggtcac gcggtaggac ggcacggctc aggccacgcc cggccggggc gccgcgtcgc
     6721 tgagcacggc gacgaggaag tcggcgtccg gggtccaggg gcgcaggtcc cacgtggcga
     6781 gcgcgaggtc gaggtgcagg cctgcctccg tggcgtcggc gaggaactgc tcgggcgggt
     6841 acccgcgacc ggtgccgaag cccacgacgg cgcggccgcc gggcgcgagg tgggcgcgga
     6901 agcggcgcag cacctccacc tcggtgcccg gcgcgaggaa cgtcacgacg ttgcccgcgc
     6961 acacgatcag gtcgaacggc tcggtgacgc cctctgcggg caggtcgagc tccgcgaggt
     7021 cgcccacgcg ccagtcgggg cctgggtggt cggtgcgcgc ggcgtcgatc aggacggggt
     7081 ccacgtcgac gcccacgacg gcgtgcccgc gcgcgaacag ctcggcgccc acgcgccccg
     7141 gcccgcagcc cgcgtcgagg acccgggagc cgcgcggcag catggcgtcg accaggcggg
     7201 cctcgcccgc gaggtcggcg ccccgggcgg ccatggcccg gaagcgttcg acgtaccagg
     7261 tggagtgcga ggggtcggcg gcggtcttct gctcccagcg cgagggacgg gtggcgctca
     7321 tgccgccgac gctacccggg cgtgggagag tcggtcccgt gaccttggtc cccaccaccc
     7381 tcggcaccac cctcggcatc gacctcggga cgagcgggct caagctcgtc ctcctcggcc
     7441 gggacgggtc ggtcgtcgcg gaggccgagg cggcgtacga cgtcgagcac ccgcgtcccg
     7501 gccgctccga gtcggccccg acgacctgga cgacggcgct cggcgccgcc ctcgacgacc
     7561 tcgccgccca cgcggccggg ctcggcgagg tcgcggtgcg cgcggtcggc gtcgcgggcc
     7621 agatgcacgc cgcggtgctc gtggacgcgg cgggggacgc cgtcgtgcca gccgtcctgt
     7681 ggacggacgc gcgcgcggcc gaccggctcg accgctggcg cgcgctgccc gacgccgtgc
     7741 gcgccccgct cgccaacccc ctcgtgccgg ggatgaccgg gcccgtgctc gactggttcg
     7801 ccgcgcacga ccgcgcgacg ctcgaccgcg cggcgcacgt gctgctgccc aaggacgtcg
     7861 tgcgcgcgtg gctcgtcgac gacctcgcgc tcccggtcgc cacgaccgac cggtccgacg
     7921 ccgcgggcac gctcctgtgg gacgtgcccc gcgacgcctg ggcggccgac gtcgtcgcgc
     7981 acctcgacct gccggcccgg ctcctgccgg gcgtggcgcc gtcggacgcc gtggccggga
     8041 cgaccgcccg gctcgcgcgg tggttgccgg cgagcgggag cgcggtgccc gtcgtggtgg
     8101 gcggcgggga caccccggcc gcgcggctcg ccgtcggggc gcccgggctg cacgtcaacc
     8161 tcggcacggg ggcgcaggtc atggccgcgc tcgaccgccc cgagcccgtg ctcgaccccc
     8221 tcgtgcacac cttcgcggac accggcgccg gatccgccgc gcggtggtac cgcctcgcgg
     8281 cggtgcagaa cgcgggcctg gcgctcggct gggcgctgcg ggtcctcggg ctgggctggt
     8341 ccgacggcct cgcgctcgcg cggaccgtgc ccgacggcgc gggcggcgtg acgttcctgc
     8401 cgttcctcac cggggagcgc ggcggggtcg ccggtcccga cgcgcgcggc gcgtggaccg
     8461 ggctgcgcga ggacacgggg cggcccgagc tcgtgcgcgc cgccgtcgag ggcatggtgt
     8521 tcgcggtcgc ggcggcggtc gacctgctcg acgcggcgcc cgcggccccg gtcgtggcgc
     8581 ccgtcgcggg agcgcccggg agccgtccgg acggcgagcc gggtgcggtg gtcgtgacgg
     8641 gcggcgggtc gcgcgacccg ctcgtgcgcc ggctcctcgc cgacgcgctc ggccggcccg
     8701 tccaccgggt cgggctccgc agcgcgaccg cggtcggcgc ggcgctgctc gccgcgcgcg
     8761 gcacgggcga cccggtcgag ccggtcgtgg acacggacga gccggagctc ccgggcccgg
     8821 gccgggcgga cgtcgtcggg cacctcgcgc gctggcggga ggccgccgcg gccctcgcgt
     8881 gacgcacccg gggccgaccc tgcgagaatc gagggatgtc caccgcagcc gccgtgacca
     8941 ccgggaccgc acccgtcacg gacctcgcct ccagcgcccc cacgggcgag atcctcgcgg
     9001 tgtgccgcgt gcacgccctc ctgccggacg cggggcccgt cggcgtcacg gcgatcgaca
     9061 agcgtcccgt cacgggaccg gtgaaggtgc gccggctcgg gctctacgcg gacctgcagg
     9121 ccgaccgcgc gaaccacggc ggcgaggagc aggcggtgta cgcgtacggg caggacgacg
     9181 cggactggtg ggccggcgag ctcggtcgcg acgtcccgcc gggcctgttc ggcgagaacc
     9241 tgcgcgtgga gggcatcccg gtcacggagg ccgtcgtcgg cgagcggtgg gccgtgggca
     9301 ccgcgctcct cgaggtcacc cagccgcgca cgccctgctc gacgttcgcg cgccgcctcg
     9361 gcgaggaccg gtgggtcaag cggttcacgg tcgcgaaccg caccggcgcg tacctgcgcg
     9421 tcgtgcagca cggcgagctg cgcgcgggcg acgcggtgac ggtctgctac cggcccgagc
     9481 acggggtgac gctcgccgac tggttcggcg cctggaacgg tcgcggcgcg gaccccgagc
     9541 gcgcggccgg gctcgcgcgc cgcctcctcg ccgcccacct cgagggcgac gtcacgctca
     9601 cggacgagct gcgcgcccgc gccgagatcg cggccggacg ccggatcgag gactgagcgt
     9661 cagcgctccg cgcgggggat gcgcgggccg cgccggccgc ggggcggctc gttcggcggc
     9721 cactcgccgt cgtcggagcc gtcgtcggcg gtgaagagca ggtcgtgcag gcgcacctgg
     9781 acgttctcga cgtccggcac gtcgtggagg ttcagcccgg gcttgtcggt cgcgtccgag
     9841 atgacgaggg tgccgcagcc gaagatccgg tcgatcgggc ccttctcgta gttgacgtcg
     9901 ttgatccggt agagcgggat gtcgcggccg gtgcgcgtga tgatccccga gcgcatggcg
     9961 atgcgcttgt tcgtcaccgt gtactccgtg gtgcgccagc gcagccacgg cacgaacacc
    10021 cagaccaccg ccgcgaccag cgcgagaccc gccacgaccc accggacgac gtcgttcggg
    10081 acgagcagga ccgtgaccac gacggcggcg accagcacga gcagcagcac gaacggccag
    10141 aacagcgcct tggcgtgctc cttgagctcc atgacgacgt gctcgccctc ggtgaggtgc
    10201 ttctcgctca gtcccatggg cagcatcgtg ccacccgcgc tacccctgcg cggccaggtt
    10261 ccaaccctcg accgtgcgca gcccgtgccc gtagccg
//
