LOCUS       NZ_CP072387.1           8602 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP072387.1 Cellulosimicrobium cellulans strain ORNL-0100
            chromosome, complete genome.
ACCESSION   NZ_CP072387
VERSION     NZ_CP072387.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:25:24
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3194711
            Orig. end    :: 3203313
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1206)
                     /locus_tag="ctg1_2813"
                     /transl_table=11
                     /translation="VTENDARTGVRDAASTHPDLPDVAGGPDDAPLLQLVTPAGSRVTT
                     PETDGYRERVAHLDAAALRGLYRDMVLTRRFDDEATSLQRQGELGLFAQAKGQEAAQIG
                     SGRALAPQDYVFPSYREHGVSHVRGIDPTARLRLFRGVDHGGWDPTAHNVHLYTLVIGS
                     HALHATGYAMGVQRDGLVGSGDPERDAAVVTYFGDGATSQGDVNEALVFAAVNNAPVVF
                     FCQNNQWAISEPTTRQTRVPLYRRGGGFGIPSVRVDGNDVLACYAVTAEALERARSGGG
                     PTFVEAFTYRMGAHTTSDDPTKYRSRAQEDYWRRRDPIDRLENLLRAEDAWDDAFAADL
                     AAEADALGERLREEVRALAAPDPASMFDHVYATPNAVVEREKAWFADYQQSFEEPTAEV
                     AR"
     protocluster    1..8602
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[3199274:3199565](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(4564..4854)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..8602
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8602
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="3"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     aSDomain        complement(55..1053)
                     /aSDomain="TIGR03181"
                     /aSTool="tigrfam"
                     /description="PDH_E1_alph_x: pyruvate dehydrogenase
                     (acetyl-transferring) E1 component, alpha subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2813_0013"
                     /evalue="3.70E-129"
                     /identifier="TIGR03181"
                     /label="ctg1_2813"
                     /locus_tag="ctg1_2813"
                     /protein_end="384"
                     /protein_start="51"
                     /score="428.4"
                     /tool="antismash"
                     /translation="RERVAHLDAAALRGLYRDMVLTRRFDDEATSLQRQGELGLFAQAK
                     GQEAAQIGSGRALAPQDYVFPSYREHGVSHVRGIDPTARLRLFRGVDHGGWDPTAHNVH
                     LYTLVIGSHALHATGYAMGVQRDGLVGSGDPERDAAVVTYFGDGATSQGDVNEALVFAA
                     VNNAPVVFFCQNNQWAISEPTTRQTRVPLYRRGGGFGIPSVRVDGNDVLACYAVTAEAL
                     ERARSGGGPTFVEAFTYRMGAHTTSDDPTKYRSRAQEDYWRRRDPIDRLENLLRAEDAW
                     DDAFAADLAAEADALGERLREEVRALAAPDPASMFDHVYATPNAVVEREKAW"
     PFAM_domain     complement(169..1005)
                     /aSDomain="E1_dh"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00676.22"
                     /description="Dehydrogenase E1 component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2813_0065"
                     /evalue="1.70E-69"
                     /label="ctg1_2813"
                     /locus_tag="ctg1_2813"
                     /protein_end="346"
                     /protein_start="67"
                     /score="234.1"
                     /tool="antismash"
                     /translation="RDMVLTRRFDDEATSLQRQGELGLFAQAKGQEAAQIGSGRALAPQ
                     DYVFPSYREHGVSHVRGIDPTARLRLFRGVDHGGWDPTAHNVHLYTLVIGSHALHATGY
                     AMGVQRDGLVGSGDPERDAAVVTYFGDGATSQGDVNEALVFAAVNNAPVVFFCQNNQWA
                     ISEPTTRQTRVPLYRRGGGFGIPSVRVDGNDVLACYAVTAEALERARSGGGPTFVEAFT
                     YRMGAHTTSDDPTKYRSRAQEDYWRRRDPIDRLENLLRAEDAWDDAFAADLAAEADA"
     CDS             complement(1429..1695)
                     /locus_tag="ctg1_2814"
                     /transl_table=11
                     /translation="MDNQEWEQFVEDNGWLFGGAALVLYVAVAVIFFIAYVRIIQKAGY
                     SGWWVLVGLVPILNVVMFLVFAFSRWPVLRERDALRSGGVYPR"
     CDS             complement(1752..2441)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 178.3; E-value:
                     3.3e-54)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_2815"
                     /transl_table=11
                     /translation="MIEVVGAAKFYGARTVWTGLTLSVEAGSMAGLVGSSGSGKTTLLN
                     CVGLLDRLDAGTLFVDGRDVTALSPHGRRLFRRDELGYLFQNYALIDNATVAANLDVAF
                     VSRGVRRADRARRREEVLERVGLGGYERAAVYELSGGEQQRVAVARLLLKRPRVVLADE
                     PTGALDEGNADAIVGLLRELADEGRAVVVATHNPRVEQACDTVLELGASTQHVARALVG
                     ADDDGTP"
     PFAM_domain     complement(1947..2387)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2815_0066"
                     /evalue="6.40E-29"
                     /label="ctg1_2815"
                     /locus_tag="ctg1_2815"
                     /protein_end="165"
                     /protein_start="18"
                     /score="101.3"
                     /tool="antismash"
                     /translation="GLTLSVEAGSMAGLVGSSGSGKTTLLNCVGLLDRLDAGTLFVDGR
                     DVTALSPHGRRLFRRDELGYLFQNYALIDNATVAANLDVAFVSRGVRRADRARRREEVL
                     ERVGLGGYERAAVYELSGGEQQRVAVARLLLKRPRVVLADEPT"
     CDS             complement(2458..4503)
                     /locus_tag="ctg1_2816"
                     /transl_table=11
                     /translation="MPNRSLSLAYALAVVVSLFLAFFTVQAYSEFAVRGFDAQLRVDSL
                     GTTASSAEAYGTIATFATSRDCTVAKVTFDLTDVSTRHLSVLGDGSADPGGRWLDHGVA
                     DFSRGVTTQVHPGAELGATSPVGSYGLSCGTAEAEALAAALREAGVTASADSYPTILSW
                     HRYLAGTPIPAGYAIAAVAVVLLAGCGALLNARAYAVQRLQGAPFSSILRRDLAPIGRR
                     LALHLGVAAVVCAIVLGAYNGFAQATTFLGLAGAVLAGLLLVTVTAHAVSTSAAQRIPL
                     AAAIKGESVGAWVVPAAFGVRFCALVILVASIFSAVHAGQLIAGQQAARSAWQSAGGAT
                     SVGVGGDDQARAGEFAQRLGEVVVRALDDREAVLAARQPVSAFGTVTVAPEDQPVLLVS
                     PSYLEEQDVRDAAGSRLAPAPGSCLTIHLPATLRADQQDDVVAAVGSWADYFGATCAVE
                     RGAPLAEGSTLFDYGNAADPSASPLVDEPVVLVVDPASEVVSADGYGAYTSTGDVVFLD
                     PAYVLEESRAAGIRDYVLSVTPIADAAAEEYQKLVRSFRLGLANIAAAAGVVLLTAVVV
                     SSAYTRRYAQSVFVRYIAGWSFAARYRAAFLAEAASAALLVAYVAANPPRTPPALGAVV
                     AAAAPRLLGGAEPLVAVAVCLVSSALLVTALAVAQRRLLRTRSSDS"
     CDS             complement(4564..4854)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Lactococcin_972"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2817"
                     /sec_met_domain="Lactococcin_972 (E-value: 4.5e-12,
                     bitscore: 44.2, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFGRVLTTAMVAGVLAFTPAAAFAGSQLVGGGIWNYGTSAGAIY
                     SHYLHNTQCHGASVHNGKLYRVTNIKPGVWAKVHAKDWPMRVDHAYWHKCA"
     PFAM_domain     complement(4579..4764)
                     /aSDomain="Lactococcin_972"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09683.12"
                     /description="Bacteriocin (Lactococcin_972)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2817_0067"
                     /evalue="5.30E-14"
                     /label="ctg1_2817"
                     /locus_tag="ctg1_2817"
                     /protein_end="92"
                     /protein_start="30"
                     /score="52.6"
                     /tool="antismash"
                     /translation="GGGIWNYGTSAGAIYSHYLHNTQCHGASVHNGKLYRVTNIKPGVW
                     AKVHAKDWPMRVDHAYW"
     aSDomain        complement(4612..4836)
                     /aSDomain="TIGR01653"
                     /aSTool="tigrfam"
                     /description="lactococcin_972: bacteriocin, lactococcin 972
                     family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2817_0014"
                     /evalue="1.20E-10"
                     /identifier="TIGR01653"
                     /label="ctg1_2817"
                     /locus_tag="ctg1_2817"
                     /protein_end="81"
                     /protein_start="6"
                     /score="39.5"
                     /tool="antismash"
                     /translation="LTTAMVAGVLAFTPAAAFAGSQLVGGGIWNYGTSAGAIYSHYLHN
                     TQCHGASVHNGKLYRVTNIKPGVWAKVHAK"
     CDS             complement(4975..6054)
                     /NRPS_PKS="Domain: Aminotran_1_2 (31-342). E-value:
                     6.3e-56. Score: 181.8. Matches aSDomain:
                     nrpspksdomains_ctg1_2818_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 161.8; E-value: 4e-49)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2818"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.3e-07,
                     bitscore: 28.2, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VAHEPRVPLRPAVAALPAYVPGARVAPGAAAFKLSSNENPYPPLP
                     SVVAAIADAAADANRYPDMYATELTEALAADLGVGADEVVVGNGSVAVLAHVLQAVVEP
                     GDEVVYPWRSFEAYPIAVAVAGGTSVRVPLRTGEHRGRLDLPAMAAAVTERTRVVMVCT
                     PNNPTGPAVHRDELETFLAAVSSDVLVVLDEAYLEFVRDPEAPDGLAVYAQHPNVVLLR
                     TFSKAYGLAGLRVGYAVARPRLAAGIRAVSTPFGVSHVAQRAAIASLGARGELLQRVEH
                     LVADRTRLVEGLRDQGWSLPESQANFVWFDLGERTAQRAEEARAAGAIVRPFAGEGLRV
                     SVGEPEATDLFLRVSATWL"
     aSDomain        complement(4990..6027)
                     /aSDomain="TIGR01141"
                     /aSTool="tigrfam"
                     /description="hisC: histidinol-phosphate transaminase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2818_0015"
                     /evalue="2.90E-90"
                     /identifier="TIGR01141"
                     /label="ctg1_2818"
                     /locus_tag="ctg1_2818"
                     /protein_end="355"
                     /protein_start="9"
                     /score="300.6"
                     /tool="antismash"
                     /translation="RPAVAALPAYVPGARVAPGAAAFKLSSNENPYPPLPSVVAAIADA
                     AADANRYPDMYATELTEALAADLGVGADEVVVGNGSVAVLAHVLQAVVEPGDEVVYPWR
                     SFEAYPIAVAVAGGTSVRVPLRTGEHRGRLDLPAMAAAVTERTRVVMVCTPNNPTGPAV
                     HRDELETFLAAVSSDVLVVLDEAYLEFVRDPEAPDGLAVYAQHPNVVLLRTFSKAYGLA
                     GLRVGYAVARPRLAAGIRAVSTPFGVSHVAQRAAIASLGARGELLQRVEHLVADRTRLV
                     EGLRDQGWSLPESQANFVWFDLGERTAQRAEEARAAGAIVRPFAGEGLRVSVGEPEATD
                     LFLRVS"
     aSDomain        complement(5029..5961)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2818_Aminotran_1_2.1"
                     /evalue="6.30E-56"
                     /label="ctg1_2818_Aminotran_1_2.1"
                     /locus_tag="ctg1_2818"
                     /protein_end="342"
                     /protein_start="31"
                     /score="181.8"
                     /tool="antismash"
                     /translation="FKLSSNENPYPPLPSVVAAIADAAADANRYPDMYATELTEALAAD
                     LGVGADEVVVGNGSVAVLAHVLQAVVEPGDEVVYPWRSFEAYPIAVAVAGGTSVRVPLR
                     TGEHRGRLDLPAMAAAVTERTRVVMVCTPNNPTGPAVHRDELETFLAAVSSDVLVVLDE
                     AYLEFVRDPEAPDGLAVYAQHPNVVLLRTFSKAYGLAGLRVGYAVARPRLAAGIRAVST
                     PFGVSHVAQRAAIASLGARGELLQRVEHLVADRTRLVEGLRDQGWSLPESQANFVWFDL
                     GERTAQRAEEARAAGAIVRPFAGEGLRVSV"
     PFAM_domain     complement(5029..5961)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00155.23"
                     /description="Aminotransferase class I and II"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2818_0068"
                     /evalue="2.20E-53"
                     /label="ctg1_2818"
                     /locus_tag="ctg1_2818"
                     /protein_end="342"
                     /protein_start="31"
                     /score="181.8"
                     /tool="antismash"
                     /translation="FKLSSNENPYPPLPSVVAAIADAAADANRYPDMYATELTEALAAD
                     LGVGADEVVVGNGSVAVLAHVLQAVVEPGDEVVYPWRSFEAYPIAVAVAGGTSVRVPLR
                     TGEHRGRLDLPAMAAAVTERTRVVMVCTPNNPTGPAVHRDELETFLAAVSSDVLVVLDE
                     AYLEFVRDPEAPDGLAVYAQHPNVVLLRTFSKAYGLAGLRVGYAVARPRLAAGIRAVST
                     PFGVSHVAQRAAIASLGARGELLQRVEHLVADRTRLVEGLRDQGWSLPESQANFVWFDL
                     GERTAQRAEEARAAGAIVRPFAGEGLRVSV"
     PFAM_domain     6158..6508
                     /aSDomain="Phage_holin_4_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04020.15"
                     /description="Mycobacterial 4 TMS phage holin, superfamily
                     IV"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2819_0069"
                     /evalue="2.60E-27"
                     /label="ctg1_2819"
                     /locus_tag="ctg1_2819"
                     /protein_end="117"
                     /protein_start="0"
                     /score="95.6"
                     /tool="antismash"
                     /translation="MSFVVRVLITGLAIWLTSLFMDEHFQIVGSDTAGGKVVIVLVVAL
                     LYSLVNAVIKPIVQVLSIPLYILTLGLFSLVVNALMLMLTAWITEQTDWGIRIIGGFWW
                     ALLAALIIAVINF"
     CDS             6158..6547
                     /locus_tag="ctg1_2819"
                     /transl_table=11
                     /translation="MSFVVRVLITGLAIWLTSLFMDEHFQIVGSDTAGGKVVIVLVVAL
                     LYSLVNAVIKPIVQVLSIPLYILTLGLFSLVVNALMLMLTAWITEQTDWGIRIIGGFWW
                     ALLAALIIAVINFLVSAVVPKAQDR"
     CDS             complement(6618..8288)
                     /locus_tag="ctg1_2820"
                     /transl_table=11
                     /translation="VSGSPPGPSVVIRGGTEPTVVETAGVVAQAAVLAARADLLAGAAG
                     ALRDARHAVEVTTATPTAFAGRLVPAEPLGAAAGANLTTTPFWSAEVRAARAALLDGLD
                     AAALLAGQEEQRLRGLAERLHQAIRVYDDADAAAAAGWSDTALVVAGRHYGLAGAGAAG
                     LGMIVAQGLAGLAQSLLHGGPALGRLVATGEALHPATVRALGRTIGMLDPDRPWYAVPT
                     VGNAAAVLRASVQPLRDRFLPDPEVRRVDAAPYDLPTPTDTRSALGAVAALGSTDSVLS
                     VQRIVKDGGTPTWVVAIPGTQPGNLRTVWNMTSNYDLMSDDESQRARADSVRAVLDAMS
                     QSGIEPEDDVVLVGHSQGGMVAATIAAATVGTYQVRHVVTAGSPVGGHGLPPGVRATHL
                     ETSGEGVSGLDGKPNPATPERVTVTGTVFAPGGGPPLDVPHSVGYHQDVLDAAVEVGDR
                     GLEEHLADVEHWLDGEAEDPLVYEARLVPDPETTFCVGELAVPRPPWPPWPAPDGVVTA
                     PGPSLGTPGTSGTAGGSGTLGGTGTLGGAGAGGGEDDAR"
     PFAM_domain     complement(7128..7322)
                     /aSDomain="LIP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03583.16"
                     /description="Secretory lipase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2820_0070"
                     /evalue="3.20E-05"
                     /label="ctg1_2820"
                     /locus_tag="ctg1_2820"
                     /protein_end="387"
                     /protein_start="322"
                     /score="23.5"
                     /tool="antismash"
                     /translation="ESQRARADSVRAVLDAMSQSGIEPEDDVVLVGHSQGGMVAATIAA
                     ATVGTYQVRHVVTAGSPVGG"
     CDS             complement(8285..8602)
                     /locus_tag="ctg1_2821"
                     /transl_table=11
                     /translation="MPTPPPPPCLAAPFGITRARDQVRTATDDAARAGAALETPDLPWA
                     GQARHAYDDATAEVRAALLRLDETLGTCLVRLDALTVLAEADVTSLRAGLAAGLATGGG
                     S"
ORIGIN
        1 tcatcgcgcc acctccgcgg tcggctcctc gaaggactgc tggtagtcgg cgaaccacgc
       61 cttctcgcgc tcgaccacgg cgttcggggt cgcgtagacg tggtcgaaca tgctcgccgg
      121 gtccggtgcg gcgagcgcgc ggacctcctc gcgcagccgc tcgcccagcg cgtcggcctc
      181 ggcggccagg tcggcggcga acgcgtcgtc ccacgcgtcc tcggcgcgga gcaggttctc
      241 gagccggtcg atcgggtccc gacggcgcca gtagtcctcc tgggcgcgcg accggtactt
      301 cgtcgggtcg tcggacgtcg tgtgcgcgcc catgcggtac gtgaaggctt cgacgaacgt
      361 cgggccgccg ccggagcggg cgcgctcgag cgcctccgcg gtcacggcgt agcacgcgag
      421 cacgtcgttg ccgtcgaccc gcacgctggg gatgccgaac ccaccgccgc ggcggtagag
      481 cggcacgcgg gtctgccggg tcgtcggctc cgagatcgcc cactggttgt tctggcagaa
      541 gaagacgacc ggcgcgttgt tcacggccgc gaagacgagc gcctcgttga cgtcgccctg
      601 cgaggtcgcg ccgtcgccga agtacgtgac gacggccgcg tcgcgctccg ggtcgcccga
      661 cccgacgagg ccgtcgcgct ggacgcccat ggcgtacccc gtggcgtgca gcgcgtgcga
      721 cccgataacg agcgtgtaca ggtggacgtt gtgcgccgtc gggtcccacc cgccgtggtc
      781 cacgccgcga aagaggcgca ggcgcgccgt cgggtcgatg ccgcgcacgt gcgagacgcc
      841 gtgctcgcgg tacgacggga agacgtagtc ctggggggcg agcgcgcggc ccgagccgat
      901 ctgcgcggcc tcctggccct tcgcctgcgc gaacaggccg agctcgccct ggcgctggag
      961 cgacgtcgcc tcgtcgtcga agcggcgcgt gagcaccatg tcgcggtaga gaccgcgcag
     1021 cgccgcggcg tcgaggtggg cgacgcgctc gcggtagccg tcggtctccg gggtcgtgac
     1081 gcgggagccg gcgggcgtca cgagctggag caggggtgcg tcgtcgggac cgcccgcgac
     1141 gtcggggagg tcggggtgcg tgctcgcagc gtcccgcacg ccggttctcg cgtcgttctc
     1201 ggtcacgcga ctctccttcg gtgcggcccg gccgtgcggc cggcccgctc gggggcagga
     1261 ggcgcccggt gcggggcgcc gtcggaacct acgtctccgt agcctacgca agcgtaggct
     1321 acgaccccgt aggtagcgcc tccgacgtgt cgcccaacgt ccgtcacgac cggctgtagg
     1381 gaacctccaa tccccaccgg cgcacccccg gccccgggag ggctgcccct accgcgggta
     1441 gacgccgccc gagcgcagcg cgtcgcgctc gcgcaggacc ggccagcgcg agaacgcgaa
     1501 cacgaggaac atgacgacgt tgaggatcgg cacgaggccc acgagcaccc accagccgga
     1561 gtagccggcc ttctggatga tccggacgta ggcgatgaag aagatcaccg cgaccgcgac
     1621 gtagaggacc agggccgcgc ccccgaagag ccagccgttg tcctcgacga actgctccca
     1681 ctcctggttg tccatgccgc gagtcttctc gcgtgaccag gacccggcaa ccgcgccgcg
     1741 ggcgcccgcc gctacggcgt gccgtcgtcg tccgcgccga cgagcgcgcg ggccacgtgc
     1801 tgggtcgagg cgccgagctc gaggacggtg tcgcaggcct gctcgacgcg cgggttgtgc
     1861 gtcgcgacga ccacggcacg cccctcgtcc gcgagctcgc gcaggaggcc gacgatcgcg
     1921 tcggcgttcc cctcgtcgag cgcccccgtg ggctcgtcgg cgagcacgac gcgcggccgc
     1981 ttgaggagca gccgcgccac ggcgacgcgc tgctgctcgc cgcccgacag ctcgtagacg
     2041 gccgcgcgct cgtagccgcc gagccccacg cgctcgagca cctcctcgcg ccggcgcgcg
     2101 cggtccgccc gccggacgcc ccggctcacg aacgcgacgt cgaggttcgc cgcgaccgtc
     2161 gcgttgtcga tgagcgcgta gttctggaac aggtacccga gctcgtcccg tcggaacagg
     2221 cgtcgcccgt gcgggctcag cgcggtgacg tcgcggccgt ccacgaacag cgtccccgcg
     2281 tccagccggt cgagcaggcc cacgcagttg agcagcgtcg tcttccccga gccgctcgac
     2341 cccacgaggc ccgccatcga gcctgcctcc acgctcagcg tgaggcccgt ccagaccgtc
     2401 cgcgccccgt agaacttggc cgcacccacg acctcgatca tcgccatccc ccttcgttca
     2461 gctgtcactg gatcgcgtcc gcaggagccg gcgctgagcc accgcgagcg cggtcaccag
     2521 cagggcggac gacacgaggc acaccgccac cgcgacgagc ggctccgctc ccccgagcag
     2581 ccgcggcgcg gcggccgcca cgacggcgcc gagggccggc ggcgtgcgcg gcgggttcgc
     2641 cgccacgtac gcgacgagca gcgccgccga ggcggcctcg gcgaggaacg ccgcgcggta
     2701 ccgcgccgcg aacgaccacc ccgcgatgta gcggacgaac acgctctgcg cgtaccgccg
     2761 cgtgtacgcg ctcgacacga cgaccgcggt gaggagcacg acgccggccg ccgccgcgat
     2821 gttcgcgagc ccgagccgga agctccggac gagcttctgg tactcctcgg ccgcggcgtc
     2881 ggcgatcggc gtgaccgaga ggacgtagtc gcggatgccc gccgcgcggc tctcctccag
     2941 cacgtacgcc gggtcgagga agacgacgtc ccccgtcgag gtgtacgcgc cgtacccgtc
     3001 ggcgctcacg acctccgagg ccgggtccac gacgagcacg accggctcgt ccacgagcgg
     3061 cgacgcgctc gggtccgctg cgttgccgta gtcgaacagc gtgctgccct cggcgagcgg
     3121 cgcaccgcgc tcgacggcgc acgtcgcacc gaagtagtcc gcccacgagc cgacggcggc
     3181 cacgacgtcg tcctgctggt ccgcccgcag cgtggccggc aggtggatcg tgaggcacga
     3241 ccccggcgcc ggggcgagcc gcgacccggc ggcgtcgcgg acgtcctgct cctccaggta
     3301 cgaggggctg acgaggagga ccggctggtc ctcgggcgcg accgtcaccg tgccgaacgc
     3361 cgagacgggc tgccgcgcgg cgagcaccgc ctcgcggtcg tcgagggccc gcacgacgac
     3421 ctcgccgagg cgctgcgcga actcgcccgc ccgggcctgg tcgtcgccgc ccacgcccac
     3481 ggaggtcgcg ccgcccgcgc tctgccaggc ggagcgggcg gcctgctggc ccgcgatgag
     3541 ctggcccgcg tgcacggcgg agaagatcga cgcgacgagg atgacgaggg cgcagaaccg
     3601 cacgccgaac gcggcgggga cgacccaggc cccgacggac tcgcccttga tcgcggccgc
     3661 gagcgggatg cgctgcgcgg cggacgtcga gacggcgtgg gcggtcacgg tgacgagcag
     3721 cagcccggcg aggacggcgc cggccaggcc gaggaacgtc gtcgcctgcg cgaacccgtt
     3781 gtaggcgccg agcacgatcg cgcacacgac ggcggccaca ccgaggtgga gggcgaggcg
     3841 ccggccgatc ggggcgaggt cgcgccgcag gatgctggag aacggcgcgc cctggaggcg
     3901 ctggaccgcg tacgcccggg cgttgaggag cgcgccgcac cccgcgagga gcacgacggc
     3961 gaccgccgcg atggcgtagc ccgccgggat cggcgtgccc gcgaggtagc ggtgccacga
     4021 gaggatcgtc gggtaggagt cggccgacgc cgtcaccccg gcctcccgca gcgcggcggc
     4081 cagcgcctcg gcctccgccg tgccgcacga gaggccgtag gagcccaccg ggctcgtggc
     4141 cccgagctcg gcaccggggt gcacctgcgt ggtgacgccg cggctgaagt cggcgacgcc
     4201 gtggtcgagc caccgcccgc ccgggtcggc cgagccgtca ccgaggaccg agaggtgccg
     4261 cgtcgagacg tcggtgaggt cgaaggtcac cttggcgacg gtgcagtcgc gggaggtcgc
     4321 gaaggtcgcg atcgtgccgt acgcctcggc gctcgacgcg gtcgtgccga gggagtcgac
     4381 gcggagctgg gcgtcgaacc cgcggaccgc gaactcgctg tacgcctgca ccgtgaagaa
     4441 ggcgaggaag aggctgacga ccaccgcgag ggcgtaggcc aggctgaggc ttctgttcgg
     4501 catggaggct ccgcgccgga ccgggcaggg acggcacggc gccgcccctg ccctgcgtcc
     4561 gtgctacgcg cacttgtgcc agtaggcgtg gtccacgcgc atgggccagt ccttggcgtg
     4621 caccttcgcc cagaccccgg gcttgatgtt ggtcacccgg tagagcttcc cgttgtgcac
     4681 ggacgcgccg tggcactggg tgttgtgcag gtagtgcgag tagatcgccc ccgcactggt
     4741 cccgtagttc cagatcccgc cgcccacgag ctgcgagccg gcgaacgccg ccgccggtgt
     4801 gaaggccagg accccggcga ccatcgccgt cgtcagtact cgaccaaacc tcatatctcc
     4861 cccttcggaa gtgattgcta cgtaaaagta gcaatccgga gaggcgagca ccaggggttc
     4921 gctcgatctg gggaagttcc gttgccggaa cgcagagggg ccgtcgaggg agggctacag
     4981 ccaggtcgcg ctgacgcgca ggaagaggtc ggtcgcctcg ggctcgccca cgctcacgcg
     5041 caggccctcg cccgcgaacg ggcgcacgat cgcgccggcg gcacgcgcct cctcggcgcg
     5101 ctgggccgtg cgctccccca ggtcgaacca cacgaagttc gcctgcgact ccggcaggga
     5161 ccagccctgg tcgcgcagac cctcgacgag gcgggtgcgg tccgccacga ggtgctcgac
     5221 ccgctgcagg agctcgcccc gcgccccgag cgacgcgatc gcggcccgct gcgccacgtg
     5281 cgagaccccg aacggcgtgg agacggcacg gatgcccgcc gccaggcgcg gacgcgcgac
     5341 ggcgtacccg acgcgcaggc ccgcgagccc gtacgccttg gagaacgtgc gcagcagcac
     5401 gacgttcggg tgctgcgcgt acaccgcgag accgtcgggg gcctccgggt cgcgcacgaa
     5461 ctcgaggtac gcctcgtcga gcaccacgag cacgtccgac gacaccgccg cgaggaacgt
     5521 ctcgagctcg tcgcggtgca cggccggacc ggtcgggttg ttgggcgtgc acaccatgac
     5581 gacgcgcgtg cgctcggtga ccgccgcggc catcgcgggc aggtcgaggc gcccgcggtg
     5641 ctcccccgtc cggagcggga cccgcaccga cgtgccgccc gcgacggcga ccgcgatcgg
     5701 gtatgcctcg aacgagcgcc acgggtagac gacctcgtcg cccggctcga cgaccgcctg
     5761 gagcacgtgc gcgagcaccg cgaccgagcc gttgcccacg acgacctcgt cggcccccac
     5821 cccgaggtcc gccgcgagcg cctcggtgag ctcggtcgcg tacatgtccg ggtagcggtt
     5881 cgcgtccgcc gcggcgtcgg cgatcgccgc cacgaccgag ggcagtggcg ggtacgggtt
     5941 ctcgttcgag gagagcttga acgccgccgc acccggggcg acgcgcgccc ccgggacgta
     6001 ggccggcagg gcggcgacgg caggacgcag ggggacgcgg ggttcgtggg ccacggtcct
     6061 cgatcatgcc actcgtgcac cgcggtccgt ggccgacgac ggcgcgccac gcgcggcgcc
     6121 cgtgccgcac gaccgcccgg atggcaggat gccgggtatg agcttcgtcg tccgcgtcct
     6181 catcaccggt ctcgcgatct ggctcacgag cctgttcatg gacgagcact tccagatcgt
     6241 cggctccgac acggccggcg gcaaggtcgt gatcgtcctc gtcgtggcgc tgctctactc
     6301 gctcgtgaac gcggtgatca agccgatcgt gcaggtcctc tcgatcccgc tctacatcct
     6361 cacgctgggg ctgttctcgc tcgtcgtcaa cgcgctcatg ctcatgctca ccgcgtggat
     6421 caccgagcag acggactggg gcatccgcat catcggcggg ttctggtggg cgctgctcgc
     6481 ggccctcatc atcgcggtca tcaacttcct cgtctcggcc gtcgtgccga aggcccagga
     6541 ccgctgaccc gagcgctctg ccgcgcgcgc cgccgctcac cctcccgacc ggcccgccgg
     6601 gaggcggcac cgggccgtca ccgcgcatcg tcctcgccac cacccgcccc ggcgcccccg
     6661 agcgtgcccg tgccgccgag cgtgccggag ccgcccgccg tcccggacgt ccccggcgtg
     6721 ccgagggacg gacccggcgc cgtcacgacg ccgtccggag ccggccacgg gggccacggc
     6781 ggcctcggca ccgcgagctc accgacgcag aacgtcgtct cggggtccgg gacgagacgc
     6841 gcctcgtaga cgagcgggtc ctccgcctcg ccgtcgagcc agtgctccac gtcggcgagg
     6901 tgctcctcga ggccgcggtc gcccacctcg accgcggcgt cgagcacgtc ctggtggtag
     6961 ccgacggagt gcggcacgtc gagcggcggc ccgccgccgg gcgcgaagac ggtaccggtc
     7021 accgtcacgc gctcgggcgt cgccgggttc ggcttcccgt cgaggccgga gaccccctcc
     7081 ccgctggtct cgaggtgcgt cgcgcgcacg cccggcggga ggccgtgccc cccgaccggt
     7141 gacccggcgg tcacgacgtg gcgcacctgg taggtcccga ccgtcgccgc cgcgatcgtg
     7201 gcggcgacca tgccgccctg gctgtgcccg acgagcacga cgtcgtcctc gggctcgatg
     7261 cccgactggc tcatcgcgtc gagcaccgcc cgcacgctgt ccgcccgcgc gcgctgggac
     7321 tcgtcgtcgg acatgaggtc gtagttggac gtcatgttcc acaccgtccg gaggttgccg
     7381 ggctgggtgc ccgggatcgc gacgacccac gtgggcgtcc cgccgtcctt cacgatgcgc
     7441 tggacgctca gcaccgagtc cgtgctcccg agcgccgcca cggcgccgag ggcggaccgc
     7501 gtgtccgtgg gggtcggcag gtcgtagggc gccgcgtcga cccgccgcac ctccgggtcg
     7561 ggcaggaacc ggtcgcgcag cggctggacg gacgcccgca gcaccgccgc cgcgttcccg
     7621 accgtcggca cggcgtacca ggggcggtcc gggtcgagca tgccgatcgt gcgacccagc
     7681 gcgcggacgg tcgcggggtg cagcgcctcg cccgtcgcga cgagccgacc gagagcgggc
     7741 cctccgtgca gcagcgactg cgcgagcccg gcgaggccct gcgcgacgat catcccgagc
     7801 ccggcggcgc ccgcccccgc cagcccgtag tgccgtcccg ccacgaccag cgcggtgtcg
     7861 gaccacccgg cggcggccgc ggcgtccgcg tcgtcgtaca cccggatcgc ctggtgcagc
     7921 cgctcggcga gcccgcgcag ccgctgctcc tcctgcccgg cgagcagggc cgccgcgtcg
     7981 aggccgtcga ggagggccgc gcgcgcggcc cggacctccg ccgaccagaa cggcgtcgtc
     8041 gtcaggttcg cgcccgcggc cgccccgagc ggctcggccg ggacgagccg cccggcgaac
     8101 gccgtcggcg tggccgtcgt gacctccacc gcgtgccgcg cgtcccgcag cgcccctgcc
     8161 gctcccgcca ggagatccgc acgggccgcg agcaccgcgg cctgcgcgac gacccccgcc
     8221 gtctcgacga ccgtcggctc cgtcccgcca cggatcacga cggacggtcc gggcggcgac
     8281 ccgctcacga gccgcccccc gtggcgagcc ccgcggccag gcccgcccgc aggctcgtga
     8341 cgtccgcctc cgcgagcacg gtgagcgcgt ccagccgcac gaggcacgtc ccgagcgtct
     8401 cgtcgagccg gagcagggct gcccgcacct ccgccgtcgc gtcgtcgtac gcgtgccgcg
     8461 cctgcccggc ccacgggagg tcgggggtct cgagggcggc gccggcgcgc gcggcgtcgt
     8521 cggtcgccgt gcggacctgg tcgcgggcac gggtgatccc gaagggtgcg gcgaggcacg
     8581 gcggtggtgg tggggtcggc at
//
