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Overview
1.1
1.2
1.3
1.4
1.5

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP022096.2

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1 | cyclic-lactone-autoinducer | 854,773 | 875,482 |
Region 2 | siderophore | 1,020,313 | 1,033,518 | staphyloferrin A | Other:Non-NRP siderophore | 50%
Region 3 | T3PKS | 1,363,947 | 1,405,113 |
Region 4 | terpene | 1,715,069 | 1,735,923 |
Region 5 | siderophore | 1,741,851 | 1,755,122 |

NZ_CP022096.2 - Region 1 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 854,773 - 875,482 nt. (total: 20,710 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001291.1 |  | 0.18 | RiPP | enterocin NKR-5-3B | Enterococcus faecium
BGC0000207.1 |  | 0.13 | Polyketide | chartreusin | Streptomyces chartreusis
BGC0000540.1 |  | 0.12 | RiPP | paenibacillin | Paenibacillus polymyxa OSY-DF
BGC0001364.1 |  | 0.11 | RiPP | cinnamycin B | Actinomadura atramentaria DSM 43919
BGC0001687.1 |  | 0.09 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSL12
BGC0001053.1 |  | 0.07 | NRP, Polyketide | tubulysin A | Archangium disciforme
BGC0001872.1 |  | 0.07 | Polyketide | fabclavine-polyamine | Xenorhabdus bovienii SS-2004
BGC0001836.1 |  | 0.06 | Polyketide | tartrolon D, tartrolon F, tartrolon G | Gynuella sunshinyii YC6258
BGC0001130.1 |  | 0.06 | NRP, Polyketide | fabclavine Ia | Xenorhabdus budapestensis
BGC0001812.1 |  | 0.05 | Polyketide | tylactone | Micromonospora chalcea subsp. izumensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001291.1 |  | 0.49 | RiPP | enterocin NKR-5-3B | Enterococcus faecium
BGC0000207.1 |  | 0.42 | Polyketide | chartreusin | Streptomyces chartreusis
BGC0000540.1 |  | 0.40 | RiPP | paenibacillin | Paenibacillus polymyxa OSY-DF
BGC0001364.1 |  | 0.37 | RiPP | cinnamycin B | Actinomadura atramentaria DSM 43919
BGC0001687.1 |  | 0.34 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSL12
BGC0001053.1 |  | 0.29 | NRP, Polyketide | tubulysin A | Archangium disciforme
BGC0001872.1 |  | 0.29 | Polyketide | fabclavine-polyamine | Xenorhabdus bovienii SS-2004
BGC0001836.1 |  | 0.27 | Polyketide | tartrolon D, tartrolon F, tartrolon G | Gynuella sunshinyii YC6258
BGC0001130.1 |  | 0.25 | NRP, Polyketide | fabclavine Ia | Xenorhabdus budapestensis
BGC0001812.1 |  | 0.24 | Polyketide | tylactone | Micromonospora chalcea subsp. izumensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP022096.2 - Region 2 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,020,313 - 1,033,518 nt. (total: 13,206 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000944.1 |  | 0.29 | Other (Non-NRP siderophore) | staphyloferrin A | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000883.1 |  | 0.17 | Other | arginomycin | Streptomyces arginensis
BGC0001783.1 |  | 0.14 | Other | streptonigrin | Streptomyces flocculus
BGC0001850.1 |  | 0.14 | Other (Shikimate-derived) | diazaquinomycin A, diazaquinomycin E, diazaquinomycin F, diazaquinomycin G | Streptomyces sp. F001
BGC0000024.1 |  | 0.06 | Polyketide | aureothin | Streptomyces thioluteus
BGC0000179.1 |  | 0.04 | Polyketide | etnangien | Sorangium cellulosum So ce56
BGC0001386.1 |  | 0.04 | Polyketide | JBIR-76, JBIR-77 | Streptomyces sp. RI-77
BGC0001622.1 |  | 0.04 | Polyketide | isatropolone A, isotropolone B, isotropolone C | Streptomyces sp.
BGC0000343.1 |  | 0.04 | NRP | enterobactin | Pseudomonas sp. J465
BGC0000088.1 |  | 0.04 | Polyketide | monacolin K | Aspergillus terreus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000944.1 |  | 0.62 | Other (Non-NRP siderophore) | staphyloferrin A | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000883.1 |  | 0.49 | Other | arginomycin | Streptomyces arginensis
BGC0001783.1 |  | 0.44 | Other | streptonigrin | Streptomyces flocculus
BGC0001850.1 |  | 0.43 | Other (Shikimate-derived) | diazaquinomycin A, diazaquinomycin E, diazaquinomycin F, diazaquinomycin G | Streptomyces sp. F001
BGC0000024.1 |  | 0.25 | Polyketide | aureothin | Streptomyces thioluteus
BGC0000179.1 |  | 0.20 | Polyketide | etnangien | Sorangium cellulosum So ce56
BGC0001386.1 |  | 0.20 | Polyketide | JBIR-76, JBIR-77 | Streptomyces sp. RI-77
BGC0001622.1 |  | 0.19 | Polyketide | isatropolone A, isotropolone B, isotropolone C | Streptomyces sp.
BGC0000343.1 |  | 0.19 | NRP | enterobactin | Pseudomonas sp. J465
BGC0000088.1 |  | 0.19 | Polyketide | monacolin K | Aspergillus terreus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP022096.2 - Region 3 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,363,947 - 1,405,113 nt. (total: 41,167 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T3PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000286.1 |  | 0.22 | Polyketide | viguiepinol | Streptomyces sp. KO-3988
BGC0000770.1 |  | 0.18 | Saccharide | lipo-oligosaccharide | Campylobacter jejuni
BGC0000509.1 |  | 0.18 | RiPP | epilancin 15x | Staphylococcus epidermidis
BGC0000867.1 |  | 0.17 | Other | polyhydroxyalkanoic acids | Ectothiorhodospira shaposhnikovii
BGC0000866.1 |  | 0.17 | Other | polyhydroxyalkanoate | Burkholderia sp. DSM 9242
BGC0000218.1 |  | 0.17 | Polyketide | doxorubicin | Streptomyces peucetius
BGC0001739.1 |  | 0.16 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0001104.1 |  | 0.16 | NRP, Polyketide | myxovirescin A1 | Myxococcus xanthus DK 1622
BGC0000784.1 |  | 0.16 | Saccharide | O-antigen | Pseudomonas aeruginosa
BGC0000205.1 |  | 0.16 | Polyketide | bryostatin | Candidatus Endobugula sertula

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000286.1 |  | 0.55 | Polyketide | viguiepinol | Streptomyces sp. KO-3988
BGC0000770.1 |  | 0.50 | Saccharide | lipo-oligosaccharide | Campylobacter jejuni
BGC0000509.1 |  | 0.49 | RiPP | epilancin 15x | Staphylococcus epidermidis
BGC0000867.1 |  | 0.49 | Other | polyhydroxyalkanoic acids | Ectothiorhodospira shaposhnikovii
BGC0000866.1 |  | 0.48 | Other | polyhydroxyalkanoate | Burkholderia sp. DSM 9242
BGC0000218.1 |  | 0.48 | Polyketide | doxorubicin | Streptomyces peucetius
BGC0001739.1 |  | 0.47 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0001104.1 |  | 0.47 | NRP, Polyketide | myxovirescin A1 | Myxococcus xanthus DK 1622
BGC0000784.1 |  | 0.47 | Saccharide | O-antigen | Pseudomonas aeruginosa
BGC0000205.1 |  | 0.46 | Polyketide | bryostatin | Candidatus Endobugula sertula

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP022096.2 - Region 4 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,715,069 - 1,735,923 nt. (total: 20,855 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.45 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000888.1 |  | 0.28 | Other | bacilysin | Bacillus sp. CS93
BGC0000644.1 |  | 0.25 | Terpene | carotenoid | Dietzia sp. CQ4
BGC0000650.1 |  | 0.25 | Terpene | carotenoid | Algoriphagus sp. KK10202C
BGC0001184.1 |  | 0.24 | Other | bacilysin | Bacillus velezensis FZB42
BGC0000645.1 |  | 0.23 | Terpene | carotenoid | Halobacillus halophilus DSM 2266
BGC0000637.1 |  | 0.23 | Terpene | carotenoid | Corynebacterium glutamicum
BGC0000648.1 |  | 0.21 | Terpene | carotenoid | Myxococcus xanthus
BGC0000643.1 |  | 0.21 | Terpene | carotenoid | Brevundimonas vesicularis
BGC0000634.1 |  | 0.21 | Terpene | carotenoid | Brevundimonas sp. SD212

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.76 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000888.1 |  | 0.61 | Other | bacilysin | Bacillus sp. CS93
BGC0000644.1 |  | 0.59 | Terpene | carotenoid | Dietzia sp. CQ4
BGC0000650.1 |  | 0.59 | Terpene | carotenoid | Algoriphagus sp. KK10202C
BGC0001184.1 |  | 0.58 | Other | bacilysin | Bacillus velezensis FZB42
BGC0000645.1 |  | 0.56 | Terpene | carotenoid | Halobacillus halophilus DSM 2266
BGC0000637.1 |  | 0.56 | Terpene | carotenoid | Corynebacterium glutamicum
BGC0000648.1 |  | 0.54 | Terpene | carotenoid | Myxococcus xanthus
BGC0000643.1 |  | 0.54 | Terpene | carotenoid | Brevundimonas vesicularis
BGC0000634.1 |  | 0.54 | Terpene | carotenoid | Brevundimonas sp. SD212

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP022096.2 - Region 5 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,741,851 - 1,755,122 nt. (total: 13,272 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000946.1 |  | 0.35 | Other | vibrioferrin | Vibrio parahaemolyticus
BGC0000947.1 |  | 0.30 | Other | vibrioferrin | Vibrio alginolyticus
BGC0001870.1 |  | 0.28 | Other | putrebactin, avaroferrin | Xenorhabdus budapestensis
BGC0000944.1 |  | 0.22 | Other (Non-NRP siderophore) | staphyloferrin A | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000943.1 |  | 0.15 | Other | staphylobactin | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000703.1 |  | 0.14 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0001767.1 |  | 0.09 | NRP | salinichelins | Salinispora pacifica CNY331
BGC0000349.1 |  | 0.08 | NRP | erythrochelin | Saccharopolyspora erythraea NRRL 2338
BGC0001211.1 |  | 0.08 | NRP | albachelin | Amycolatopsis alba DSM 44262
BGC0000708.1 |  | 0.08 | Saccharide | lividomycin | Streptomyces lividus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000946.1 |  | 0.68 | Other | vibrioferrin | Vibrio parahaemolyticus
BGC0000947.1 |  | 0.64 | Other | vibrioferrin | Vibrio alginolyticus
BGC0001870.1 |  | 0.62 | Other | putrebactin, avaroferrin | Xenorhabdus budapestensis
BGC0000944.1 |  | 0.55 | Other (Non-NRP siderophore) | staphyloferrin A | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000943.1 |  | 0.44 | Other | staphylobactin | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000703.1 |  | 0.42 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0001767.1 |  | 0.33 | NRP | salinichelins | Salinispora pacifica CNY331
BGC0000349.1 |  | 0.32 | NRP | erythrochelin | Saccharopolyspora erythraea NRRL 2338
BGC0001211.1 |  | 0.32 | NRP | albachelin | Amycolatopsis alba DSM 44262
BGC0000708.1 |  | 0.31 | Saccharide | lividomycin | Streptomyces lividus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names