LOCUS       NC_022571.1            21558 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_022571.1 Clostridium saccharobutylicum DSM 13864, complete
            sequence.
ACCESSION   NC_022571
VERSION     NC_022571.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:03:18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 4279376
            Orig. end    :: 4300934
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21558
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[4289376:4290934]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11558
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21558
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21558
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="11"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /tool="antismash"
     CDS             complement(948..1427)
                     /gene_functions="regulatory (smcogs) SMCOG1120:AsnC family
                     transcriptional regulator (Score: 79.5; E-value: 3.2e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_3765"
                     /transl_table=11
                     /translation="MEEILEILEKNSRYSDEQIATMTGKTVEEVREAIRDYEEKSIIAG
                     YTTLINWENTGSETVTALIEVKITPQRGEGFDKVAERIYKFSQVKACYLMSGGFDLTVI
                     IEGKTMKEVALFVSQKLAVQQYVLSTATHFVLKKYKEHGTIFKEKKVDDREAIFI"
     PFAM_domain     complement(1017..1238)
                     /aSDomain="AsnC_trans_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01037.23"
                     /description="Lrp/AsnC ligand binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3765_0320"
                     /evalue="3.00E-12"
                     /label="ctg1_3765"
                     /locus_tag="ctg1_3765"
                     /protein_end="137"
                     /protein_start="63"
                     /score="46.4"
                     /tool="antismash"
                     /translation="IEVKITPQRGEGFDKVAERIYKFSQVKACYLMSGGFDLTVIIEGK
                     TMKEVALFVSQKLAVQQYVLSTATHFVLK"
     CDS             complement(2424..4712)
                     /gene_functions="other (smcogs) SMCOG1223:ATPase (Score:
                     399.8; E-value: 4.5e-121)"
                     /gene_kind="other"
                     /locus_tag="ctg1_3766"
                     /transl_table=11
                     /translation="MKITDEVNNILLKAYEEAKERNSEYITPEHLLYAATFDENVEHAI
                     KECGGSIENLRYNLKTYIKTYVNTTRNGEPQESIEFQRVILTANEQIKYSGKEAIGVDH
                     ILSAMFNLENSYALYYLQQEGVNRRDLLYLLCHEADTSNEEEISEYDEETHEDLEEEEI
                     PSEPINSEEKTKKKKEDAFLHKFTVNLIEKAKEEHCDPLIGREDILERSIQILCRRIKN
                     NPIHVGESGVGKTAITLGLAKLISEGKVPEKLKGSSMFSLDIGSVIAGTKYRGDFEERI
                     KRILDLIGKEHKPIVYIDEIHNIVGAGSLNGGALDASNLLKPYLTDGKIKFIGATTFEE
                     YKKFFEKDKALTRRFQTIDVKEPSINEAIQILNGLKRNYEEYHNVSYTDEAIADAVKLS
                     DKYINDKYLPDKAVDIIDEAGAYARMHNENLDEKIIVDEKIIEEIISKVCSIPKQTVES
                     SEISSLKHLEADLKENIFHQDNAIEEVVRCIKMSRSGLNEEDKPVASMLFVGPTGVGKT
                     EIARCLAKKMGIELIRFDMSEYAEKHAASKLIGSPPGYVGYEEGGLLTDSIRKKPHCVL
                     LLDEIEKAHQDILSVLLQVMDYATLTDNKGRKADFRNAIIIMTSNAGARNIGKRLIGFG
                     DREVKGEAIMEEVKKFFSPEFRNRLDKIVVFNSMNDSMALDIAKKQLNDFKNKLAAKKI
                     KINFNDECISHVAKIGTSQEFGAREIARIISSKIKPLLVDEILFGKLSEGGNCSIKLED
                     EEFKLVVEK"
     aSDomain        complement(2463..4703)
                     /aSDomain="TIGR02639"
                     /aSTool="tigrfam"
                     /description="ClpA: ATP-dependent Clp protease ATP-binding
                     subunit ClpA"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3766_0073"
                     /evalue="0.00E+00"
                     /identifier="TIGR02639"
                     /label="ctg1_3766"
                     /locus_tag="ctg1_3766"
                     /protein_end="750"
                     /protein_start="3"
                     /score="1020.1"
                     /tool="antismash"
                     /translation="TDEVNNILLKAYEEAKERNSEYITPEHLLYAATFDENVEHAIKEC
                     GGSIENLRYNLKTYIKTYVNTTRNGEPQESIEFQRVILTANEQIKYSGKEAIGVDHILS
                     AMFNLENSYALYYLQQEGVNRRDLLYLLCHEADTSNEEEISEYDEETHEDLEEEEIPSE
                     PINSEEKTKKKKEDAFLHKFTVNLIEKAKEEHCDPLIGREDILERSIQILCRRIKNNPI
                     HVGESGVGKTAITLGLAKLISEGKVPEKLKGSSMFSLDIGSVIAGTKYRGDFEERIKRI
                     LDLIGKEHKPIVYIDEIHNIVGAGSLNGGALDASNLLKPYLTDGKIKFIGATTFEEYKK
                     FFEKDKALTRRFQTIDVKEPSINEAIQILNGLKRNYEEYHNVSYTDEAIADAVKLSDKY
                     INDKYLPDKAVDIIDEAGAYARMHNENLDEKIIVDEKIIEEIISKVCSIPKQTVESSEI
                     SSLKHLEADLKENIFHQDNAIEEVVRCIKMSRSGLNEEDKPVASMLFVGPTGVGKTEIA
                     RCLAKKMGIELIRFDMSEYAEKHAASKLIGSPPGYVGYEEGGLLTDSIRKKPHCVLLLD
                     EIEKAHQDILSVLLQVMDYATLTDNKGRKADFRNAIIIMTSNAGARNIGKRLIGFGDRE
                     VKGEAIMEEVKKFFSPEFRNRLDKIVVFNSMNDSMALDIAKKQLNDFKNKLAAKKIKIN
                     FNDECISHVAKIGTSQEFGAREIARIISSKIKPLLVDEILFGKLSEGGNCSIK"
     PFAM_domain     complement(2469..2693)
                     /aSDomain="ClpB_D2-small"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10431.11"
                     /description="C-terminal, D2-small domain, of ClpB protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3766_0325"
                     /evalue="2.00E-16"
                     /label="ctg1_3766"
                     /locus_tag="ctg1_3766"
                     /protein_end="748"
                     /protein_start="673"
                     /score="59.9"
                     /tool="antismash"
                     /translation="ALDIAKKQLNDFKNKLAAKKIKINFNDECISHVAKIGTSQEFGAR
                     EIARIISSKIKPLLVDEILFGKLSEGGNCS"
     PFAM_domain     complement(2724..3212)
                     /aSDomain="AAA_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07724.16"
                     /description="AAA domain (Cdc48 subfamily)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3766_0324"
                     /evalue="1.40E-45"
                     /label="ctg1_3766"
                     /locus_tag="ctg1_3766"
                     /protein_end="663"
                     /protein_start="500"
                     /score="155.5"
                     /tool="antismash"
                     /translation="KPVASMLFVGPTGVGKTEIARCLAKKMGIELIRFDMSEYAEKHAA
                     SKLIGSPPGYVGYEEGGLLTDSIRKKPHCVLLLDEIEKAHQDILSVLLQVMDYATLTDN
                     KGRKADFRNAIIIMTSNAGARNIGKRLIGFGDREVKGEAIMEEVKKFFSPEFRNRLDKI
                     "
     PFAM_domain     complement(3312..3623)
                     /aSDomain="AAA_lid_9"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17871.3"
                     /description="AAA lid domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3766_0323"
                     /evalue="3.10E-28"
                     /label="ctg1_3766"
                     /locus_tag="ctg1_3766"
                     /protein_end="467"
                     /protein_start="363"
                     /score="97.8"
                     /tool="antismash"
                     /translation="SINEAIQILNGLKRNYEEYHNVSYTDEAIADAVKLSDKYINDKYL
                     PDKAVDIIDEAGAYARMHNENLDEKIIVDEKIIEEIISKVCSIPKQTVESSEISSLKHL
                     "
     PFAM_domain     complement(3648..4037)
                     /aSDomain="AAA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00004.31"
                     /description="ATPase family associated with various
                     cellular activities (AAA)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3766_0322"
                     /evalue="3.80E-09"
                     /label="ctg1_3766"
                     /locus_tag="ctg1_3766"
                     /protein_end="355"
                     /protein_start="225"
                     /score="37.2"
                     /tool="antismash"
                     /translation="HVGESGVGKTAITLGLAKLISEGKVPEKLKGSSMFSLDIGSVIAG
                     TKYRGDFEERIKRILDLIGKEHKPIVYIDEIHNIVGAGSLNGGALDASNLLKPYLTDGK
                     IKFIGATTFEEYKKFFEKDKALTRRF"
     PFAM_domain     complement(4545..4673)
                     /aSDomain="Clp_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02861.22"
                     /description="Clp amino terminal domain, pathogenicity
                     island component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3766_0321"
                     /evalue="5.30E-07"
                     /label="ctg1_3766"
                     /locus_tag="ctg1_3766"
                     /protein_end="56"
                     /protein_start="13"
                     /score="29.7"
                     /tool="antismash"
                     /translation="AYEEAKERNSEYITPEHLLYAATFDENVEHAIKECGGSIENLR"
     CDS             complement(4716..5015)
                     /locus_tag="ctg1_3767"
                     /transl_table=11
                     /translation="METNIATKQKDKVKIKKPKNYKVVMYNDDYTTMEFVINILVSVFN
                     KNLIEAEKIMLDVHQKGNGIAGIYSYDIAMTKVANAMSLAKEQGFPFKLTVEEV"
     PFAM_domain     complement(4731..4970)
                     /aSDomain="ClpS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02617.19"
                     /description="ATP-dependent Clp protease adaptor protein
                     ClpS"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3767_0326"
                     /evalue="3.30E-30"
                     /label="ctg1_3767"
                     /locus_tag="ctg1_3767"
                     /protein_end="95"
                     /protein_start="15"
                     /score="103.8"
                     /tool="antismash"
                     /translation="KKPKNYKVVMYNDDYTTMEFVINILVSVFNKNLIEAEKIMLDVHQ
                     KGNGIAGIYSYDIAMTKVANAMSLAKEQGFPFKLT"
     CDS             complement(5282..6724)
                     /NRPS_PKS="Domain: Aminotran_1_2 (63-198). E-value: 8e-09.
                     Score: 26.9. Matches aSDomain:
                     nrpspksdomains_ctg1_3768_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /locus_tag="ctg1_3768"
                     /transl_table=11
                     /translation="LKLPLLEELLKYHDEKNLLLSMPGNKCGSAFLGNEIGEEFVKRLG
                     FLDITEVDPLDNLHCPEGVIKEAQELLAKTYNAKKAYFLVNGSSSGNLAAIFSAFNEGD
                     EILVERNCHKSIYNGLILRKLKVKYIEPIIDNENGVFLPPNRENIYKALSCCKNVKGII
                     LTYPNYFGITYDIEEIILDLKKKGLKTIIDCAHGAHFGINKRLPKSVSSLGDYVVLSAH
                     KTLPALTQGSYLLGNEENSMLEFYLKTFMTTSPSYLIMGSLDYARYYLDNYGDKNYEKL
                     IDRAEIWKEKMESTCKVHILNKFDLNKQYKDKRNNKFEQYDIDLSRYVLILPEGYSGHK
                     FLDYLRSKKIQAEMSFSRGVVLILSPVNTDDDFYKIYKAILDLDIENIAGDSGSKYYNT
                     IPEKKFEPHEVFSLDSELCEVDKCKNKIAKESIIPYPPGIPLICPGEIISEEAIDIIKD
                     YIVNKRSIIGVENNEISVVKLV"
     PFAM_domain     complement(5345..5545)
                     /aSDomain="OKR_DC_1_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03711.17"
                     /description="Orn/Lys/Arg decarboxylase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3768_0328"
                     /evalue="4.50E-10"
                     /label="ctg1_3768"
                     /locus_tag="ctg1_3768"
                     /protein_end="460"
                     /protein_start="393"
                     /score="40.0"
                     /tool="antismash"
                     /translation="SKYYNTIPEKKFEPHEVFSLDSELCEVDKCKNKIAKESIIPYPPG
                     IPLICPGEIISEEAIDIIKDYI"
     PFAM_domain     complement(5813..6715)
                     /aSDomain="OKR_DC_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01276.22"
                     /description="Orn/Lys/Arg decarboxylase, major domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3768_0327"
                     /evalue="7.50E-54"
                     /label="ctg1_3768"
                     /locus_tag="ctg1_3768"
                     /protein_end="304"
                     /protein_start="3"
                     /score="183.1"
                     /tool="antismash"
                     /translation="PLLEELLKYHDEKNLLLSMPGNKCGSAFLGNEIGEEFVKRLGFLD
                     ITEVDPLDNLHCPEGVIKEAQELLAKTYNAKKAYFLVNGSSSGNLAAIFSAFNEGDEIL
                     VERNCHKSIYNGLILRKLKVKYIEPIIDNENGVFLPPNRENIYKALSCCKNVKGIILTY
                     PNYFGITYDIEEIILDLKKKGLKTIIDCAHGAHFGINKRLPKSVSSLGDYVVLSAHKTL
                     PALTQGSYLLGNEENSMLEFYLKTFMTTSPSYLIMGSLDYARYYLDNYGDKNYEKLIDR
                     AEIWKEKMESTCKVHILNKF"
     aSDomain        complement(6131..6535)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_3768_Aminotran_1_2.1"
                     /evalue="8.00E-09"
                     /label="ctg1_3768_Aminotran_1_2.1"
                     /locus_tag="ctg1_3768"
                     /protein_end="198"
                     /protein_start="63"
                     /score="26.9"
                     /tool="antismash"
                     /translation="VIKEAQELLAKTYNAKKAYFLVNGSSSGNLAAIFSAFNEGDEILV
                     ERNCHKSIYNGLILRKLKVKYIEPIIDNENGVFLPPNRENIYKALSCCKNVKGIILTYP
                     NYFGITYDIEEIILDLKKKGLKTIIDCAHGA"
     CDS             complement(6962..8071)
                     /NRPS_PKS="Domain: Beta_elim_lyase (86-315). E-value:
                     5.1e-27. Score: 86.7. Matches aSDomain:
                     nrpspksdomains_ctg1_3769_Beta_elim_lyase.1"
                     /NRPS_PKS="type: other"
                     /locus_tag="ctg1_3769"
                     /transl_table=11
                     /translation="MLDIYMKYSLLELDGLMFKKINNIGGGYIMYSFRNDYSEGAHSRI
                     LNALVETNLEQTEGYSTDCYTQKAIDLLKRKIDRDDVDIHLLVGGTQVNLTAISAFLRP
                     HQAAIGADTSHINCHETGAIESTGHKVITMKTNDGKLTSDLIQKVVDAHTDEHMVQPKL
                     VYISNSTELGTLYTKLELEELHKCCKRNNLLLYLDGARLGSALLSEENDLTLCDIANLV
                     DAFYIGGTKNGALFGEALVICNNSLKEDFRYSIKQKGGLLAKGRLLGIQFEELFKDDLF
                     FELAKHANNMAILLKNALKEKGYEFLTDSSTNQQFPILPNDIIKKLSENYSFNIERVID
                     EKYAAIRLVTSWATDESSVLKFIEDLKKM"
     aSDomain        complement(7127..7813)
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_3769_Beta_elim_lyase.1"
                     /evalue="5.10E-27"
                     /label="ctg1_3769_Beta_elim_lyase.1"
                     /locus_tag="ctg1_3769"
                     /protein_end="315"
                     /protein_start="86"
                     /score="86.7"
                     /tool="antismash"
                     /translation="LVGGTQVNLTAISAFLRPHQAAIGADTSHINCHETGAIESTGHKV
                     ITMKTNDGKLTSDLIQKVVDAHTDEHMVQPKLVYISNSTELGTLYTKLELEELHKCCKR
                     NNLLLYLDGARLGSALLSEENDLTLCDIANLVDAFYIGGTKNGALFGEALVICNNSLKE
                     DFRYSIKQKGGLLAKGRLLGIQFEELFKDDLFFELAKHANNMAILLKNALKEKGYEFLT
                     DSSTNQQ"
     PFAM_domain     complement(7127..7813)
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01212.23"
                     /description="Beta-eliminating lyase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3769_0329"
                     /evalue="1.80E-24"
                     /label="ctg1_3769"
                     /locus_tag="ctg1_3769"
                     /protein_end="315"
                     /protein_start="86"
                     /score="86.7"
                     /tool="antismash"
                     /translation="LVGGTQVNLTAISAFLRPHQAAIGADTSHINCHETGAIESTGHKV
                     ITMKTNDGKLTSDLIQKVVDAHTDEHMVQPKLVYISNSTELGTLYTKLELEELHKCCKR
                     NNLLLYLDGARLGSALLSEENDLTLCDIANLVDAFYIGGTKNGALFGEALVICNNSLKE
                     DFRYSIKQKGGLLAKGRLLGIQFEELFKDDLFFELAKHANNMAILLKNALKEKGYEFLT
                     DSSTNQQ"
     CDS             complement(8422..9666)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3770"
                     /sec_met_domain="Peptidase_M16 (E-value: 1.3e-22, bitscore:
                     78.4, seeds: 24, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_M16_C (E-value: 3.6e-21,
                     bitscore: 74.0, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LQEYIFENNFKLIYKHTDSELTSICISIDAGAGVENEKYGVAHAT
                     EHMVYKGTRNRTEKQINEDLTNVFGFNNAMTNYPYVIYYGTLLGPDLEKGLELLSDIII
                     NPTFGDDGFKEEMDVIKQELEEWDEELEQYCEDKLFFNCFNSRRIKYPIIGTKNSLESM
                     TLSDIKKFYNKYYFPQNTSIVVISSREFEKVKYIINKYFGQWKVKLDKNDGSNKLNCKK
                     IEYEYPKVEVLNNKRNGIKTCRVEIICPIDNLTSIEMKSLRIFNQYFGEGVNSLLYDIL
                     RTENGLIYDVITKIANENYIKLYKITFNTAKENVDKAISLIKECIGKVELSQYHIDRMQ
                     MEQLIKSFKLKRLFREEQSIVLAKELATYDSMFGDYKIYIDEINGLDELTEEMIFEVGK
                     KVLKNLSIQIIEVCS"
     PFAM_domain     complement(8680..9180)
                     /aSDomain="Peptidase_M16_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05193.23"
                     /description="Peptidase M16 inactive domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3770_0331"
                     /evalue="1.30E-20"
                     /label="ctg1_3770"
                     /locus_tag="ctg1_3770"
                     /protein_end="329"
                     /protein_start="162"
                     /score="74.3"
                     /tool="antismash"
                     /translation="MTLSDIKKFYNKYYFPQNTSIVVISSREFEKVKYIINKYFGQWKV
                     KLDKNDGSNKLNCKKIEYEYPKVEVLNNKRNGIKTCRVEIICPIDNLTSIEMKSLRIFN
                     QYFGEGVNSLLYDILRTENGLIYDVITKIANENYIKLYKITFNTAKENVDKAISLIKEC
                     IGKV"
     PFAM_domain     complement(9199..9624)
                     /aSDomain="Peptidase_M16"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00675.22"
                     /description="Insulinase (Peptidase family M16)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3770_0330"
                     /evalue="2.30E-22"
                     /label="ctg1_3770"
                     /locus_tag="ctg1_3770"
                     /protein_end="156"
                     /protein_start="14"
                     /score="79.7"
                     /tool="antismash"
                     /translation="KHTDSELTSICISIDAGAGVENEKYGVAHATEHMVYKGTRNRTEK
                     QINEDLTNVFGFNNAMTNYPYVIYYGTLLGPDLEKGLELLSDIIINPTFGDDGFKEEMD
                     VIKQELEEWDEELEQYCEDKLFFNCFNSRRIKYPIIGT"
     CDS             complement(10001..11362)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3771"
                     /sec_met_domain="PF04055 (E-value: 1.8e-14, bitscore: 52.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.4e-11, bitscore: 41.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 7.3e-21, bitscore:
                     72.4, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 3.5e-07, bitscore: 28.6,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 9e-28,
                     bitscore: 94.4, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LALIHKFKQGENYFVLDVNTGAVHVVDELVYDILDDDKLRNKKEI
                     LESLKGKYDEEELSEAYDEIQELAEDGILYSEDQYEDIAHSSMEDRDYIKAICLNVIHG
                     CNLRCKYCFADEGEYHGHGGVMSADTAKKAIDYVIKRSGPRKNIEIDLFGGEPTLIMDT
                     IKEIIAYARDNEEKWGKRIRFTMTTNATLLTPEMMDYMDKEMGNIILSLDGRKEVNDNV
                     RIKPDKSGSYDDIVPNIKEMIKRRTPGKTYYVRGTFTRENTDFYQDVMAMVNEGFRELS
                     IEPVVLEDGHPLALRESDIDTIFDNYDKLYEEMATRKREGNDEFKFYHFNIDLQGGPCV
                     YKRISGCGAGFEYVAITPQGEVYPCHQFVGKEEFKLGSIYDDTYDTDLAKKFKKSHIYN
                     KPKCRECWAKFYCSGGCQANNFNFNGDMNIPYEIGCKMQKKRIECAIALKAVEK"
     aSDomain        complement(10013..11353)
                     /aSDomain="TIGR03974"
                     /aSTool="tigrfam"
                     /description="rSAM_six_Cys: SCIFF radical SAM maturase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3771_0074"
                     /evalue="2.30E-191"
                     /identifier="TIGR03974"
                     /label="ctg1_3771"
                     /locus_tag="ctg1_3771"
                     /protein_end="450"
                     /protein_start="3"
                     /score="634.5"
                     /tool="antismash"
                     /translation="IHKFKQGENYFVLDVNTGAVHVVDELVYDILDDDKLRNKKEILES
                     LKGKYDEEELSEAYDEIQELAEDGILYSEDQYEDIAHSSMEDRDYIKAICLNVIHGCNL
                     RCKYCFADEGEYHGHGGVMSADTAKKAIDYVIKRSGPRKNIEIDLFGGEPTLIMDTIKE
                     IIAYARDNEEKWGKRIRFTMTTNATLLTPEMMDYMDKEMGNIILSLDGRKEVNDNVRIK
                     PDKSGSYDDIVPNIKEMIKRRTPGKTYYVRGTFTRENTDFYQDVMAMVNEGFRELSIEP
                     VVLEDGHPLALRESDIDTIFDNYDKLYEEMATRKREGNDEFKFYHFNIDLQGGPCVYKR
                     ISGCGAGFEYVAITPQGEVYPCHQFVGKEEFKLGSIYDDTYDTDLAKKFKKSHIYNKPK
                     CRECWAKFYCSGGCQANNFNFNGDMNIPYEIGCKMQKKRIECAIALKA"
     aSDomain        complement(10073..10324)
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3771_0075"
                     /evalue="7.50E-21"
                     /identifier="TIGR04085"
                     /label="ctg1_3771"
                     /locus_tag="ctg1_3771"
                     /protein_end="430"
                     /protein_start="346"
                     /score="72.4"
                     /tool="antismash"
                     /translation="CGAGFEYVAITPQGEVYPCHQFVGKEEFKLGSIYDDTYDTDLAKK
                     FKKSHIYNKPKCRECWAKFYCSGGCQANNFNFNGDMNIP"
     PFAM_domain     complement(10142..10324)
                     /aSDomain="SPASM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13186.8"
                     /description="Iron-sulfur cluster-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3771_0333"
                     /evalue="1.90E-06"
                     /label="ctg1_3771"
                     /locus_tag="ctg1_3771"
                     /protein_end="407"
                     /protein_start="346"
                     /score="28.4"
                     /tool="antismash"
                     /translation="CGAGFEYVAITPQGEVYPCHQFVGKEEFKLGSIYDDTYDTDLAKK
                     FKKSHIYNKPKCRECW"
     PFAM_domain     complement(10757..11065)
                     /aSDomain="Fer4_12"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13353.8"
                     /description="4Fe-4S single cluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3771_0332"
                     /evalue="1.20E-10"
                     /label="ctg1_3771"
                     /locus_tag="ctg1_3771"
                     /protein_end="202"
                     /protein_start="99"
                     /score="42.1"
                     /tool="antismash"
                     /translation="NVIHGCNLRCKYCFADEGEYHGHGGVMSADTAKKAIDYVIKRSGP
                     RKNIEIDLFGGEPTLIMDTIKEIIAYARDNEEKWGKRIRFTMTTNATLLTPEMMDYMD"
     CDS             complement(11421..11558)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3772"
                     /sec_met_domain="TIGR03973 (E-value: 4.3e-23, bitscore:
                     78.9, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 9.3e-22, bitscore: 74.7,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHIKTINKPNIKNSLCKPGCKECANSCQSACKTSCTVANLECEN
                     "
     PFAM_domain     complement(11424..11555)
                     /aSDomain="SCIFF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13165.8"
                     /description="Six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3772_0334"
                     /evalue="4.10E-21"
                     /label="ctg1_3772"
                     /locus_tag="ctg1_3772"
                     /protein_end="45"
                     /protein_start="1"
                     /score="74.7"
                     /tool="antismash"
                     /translation="KHIKTINKPNIKNSLCKPGCKECANSCQSACKTSCTVANLECEN"
     aSDomain        complement(11427..11555)
                     /aSDomain="TIGR03973"
                     /aSTool="tigrfam"
                     /description="six_Cys_in_45: six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3772_0076"
                     /evalue="4.40E-23"
                     /identifier="TIGR03973"
                     /label="ctg1_3772"
                     /locus_tag="ctg1_3772"
                     /protein_end="44"
                     /protein_start="1"
                     /score="78.9"
                     /tool="antismash"
                     /translation="KHIKTINKPNIKNSLCKPGCKECANSCQSACKTSCTVANLECE"
     CDS             complement(12154..14622)
                     /locus_tag="ctg1_3773"
                     /transl_table=11
                     /translation="MTKGIFRPKLVHRKRITSMLSQIFEVPVFFISAPMGYGKTTSVRN
                     FLENKKEIQTIWFDVGNKKNDDIWMWYKFCKSIKSSNLSLSERLSEYGFPKNDNYVYEI
                     IDIIKDELKQKTVIVIDDWYDKENEYINDFLKTICLEEIFNLHIVIISRNRPSNEYIEL
                     ELKQKCIIMWQDDISFTFEETVEFFKLNGIKLSYKEKKEVYEYTGGWPSATYLALLQYH
                     NENTFDDIPKATELIKIAAYDKFDETTKEILLKLALVENFTLEQAIYITGNQKCRLIIK
                     NLISNNCFIRYDSKSKLYTMHSILKSALQEELLYSNIDFNKVNNASGDWYSKNNEDIQA
                     IKYYYKAKNFKRVLDLMERNYTIDLTSLWQRIINSVFDELNINEKINRPVAYLTYLFFY
                     ILYGNGVIARERLYEAKSIYEKDENLKDKNQVLGEIAFLESLLSMNDVEKMIEYHKKAY
                     EFFNGGTSKIANDKMPVTFGSPHFLCLYYRERGKLKESAECFEKGIKYFIRISNGGATG
                     SNYLIKAEYLFETGNVDEAELFAYKALHKAKIKKQTSIIICSLFLLMRICLNKNNRREA
                     TSKLEILIKEYQKLNIPSFLKGEEIPMGYIYGITGNLEEINKCVKNYERPKMQNISPVI
                     TLRYIVSALAMMLKESYIELEVQAETMLEVCKNKNGMFGIIYSYIFDSIAKYNLYGIEK
                     AKDSLMKAISYAKEDHVVMCFAELAPYILPILRHIEKEEEYVKVLLPNCEKFNYMYMKN
                     YSDDEKIELTPRESEVMNLVNKGYKQSEISEKLNIALITVKKHIAAVYSKLEVKNKTTA
                     LNILKEKGII"
     PFAM_domain     complement(12187..12339)
                     /aSDomain="GerE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00196.21"
                     /description="Bacterial regulatory proteins, luxR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3773_0336"
                     /evalue="2.20E-13"
                     /label="ctg1_3773"
                     /locus_tag="ctg1_3773"
                     /protein_end="812"
                     /protein_start="761"
                     /score="49.7"
                     /tool="antismash"
                     /translation="LTPRESEVMNLVNKGYKQSEISEKLNIALITVKKHIAAVYSKLEV
                     KNKTTA"
     PFAM_domain     complement(12430..13203)
                     /aSDomain="TPR_MalT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17874.3"
                     /description="MalT-like TPR region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3773_0335"
                     /evalue="3.90E-10"
                     /label="ctg1_3773"
                     /locus_tag="ctg1_3773"
                     /protein_end="731"
                     /protein_start="473"
                     /score="39.7"
                     /tool="antismash"
                     /translation="PVTFGSPHFLCLYYRERGKLKESAECFEKGIKYFIRISNGGATGS
                     NYLIKAEYLFETGNVDEAELFAYKALHKAKIKKQTSIIICSLFLLMRICLNKNNRREAT
                     SKLEILIKEYQKLNIPSFLKGEEIPMGYIYGITGNLEEINKCVKNYERPKMQNISPVIT
                     LRYIVSALAMMLKESYIELEVQAETMLEVCKNKNGMFGIIYSYIFDSIAKYNLYGIEKA
                     KDSLMKAISYAKEDHVVMCFAELAPYILPILRHIEK"
     CDS             complement(15148..17085)
                     /locus_tag="ctg1_3774"
                     /transl_table=11
                     /translation="MIKENGNISIDTENIFPIIKKWLYSDKDIFIREVISNACDAISKF
                     QRLVSLGEANIDKEESYKVTVSINKENKTLKFIDNGIGMTEEEVKKYITQVAFSGATDF
                     VEKYKDKMDEGKDIIGHFGLGFYSTFMVSDKVQIDTLSYKSEAEAVKWVCNEGGTEYEI
                     STSEERTTRGTTITLYINEESKEFLEEYKVREIIKKYCSFLPTEIYLEDENKPKEEPKY
                     VTKKKEDGTEYQELVEPEAPKPLNDTKPLWIKAPKDCTDEEYKDFYRKVFMDFNEPLFW
                     IHLNVDYPFNLKGILYFPKLTHEFEATEGQVKLYNNQVFVADNIKEVIPDFLLLLKGTI
                     DCPDLPLNVSRSFLQNDKEVSKISNHIIKKVADKLVDLFKNSREEFNKFWPDIQIFIKY
                     GCLRDQKFYEKIKDIIIFKNLKDEFVTLKDYLEANKEKHENKVFYVNDEKQQSQYIKMF
                     KEYDLDAVILNCSLDDHFISFLEMHESGVKFNRIDSDISDTLGSKTDENDETQKALNKE
                     IEHVFKTALGEKVNKLSVEALKNTETPALILVSEESRRMAQMSKMYAKSGMNFPGMFNE
                     EKTLVVNNKNTIIKKLVEVSKDDSKKDEVRTICEHIMDLAKIANKELDANEMDEFIKRS
                     NQLLSRVIEL"
     PFAM_domain     complement(15157..16530)
                     /aSDomain="HSP90"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00183.20"
                     /description="Hsp90 protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3774_0338"
                     /evalue="3.40E-64"
                     /label="ctg1_3774"
                     /locus_tag="ctg1_3774"
                     /protein_end="643"
                     /protein_start="185"
                     /score="217.9"
                     /tool="antismash"
                     /translation="EFLEEYKVREIIKKYCSFLPTEIYLEDENKPKEEPKYVTKKKEDG
                     TEYQELVEPEAPKPLNDTKPLWIKAPKDCTDEEYKDFYRKVFMDFNEPLFWIHLNVDYP
                     FNLKGILYFPKLTHEFEATEGQVKLYNNQVFVADNIKEVIPDFLLLLKGTIDCPDLPLN
                     VSRSFLQNDKEVSKISNHIIKKVADKLVDLFKNSREEFNKFWPDIQIFIKYGCLRDQKF
                     YEKIKDIIIFKNLKDEFVTLKDYLEANKEKHENKVFYVNDEKQQSQYIKMFKEYDLDAV
                     ILNCSLDDHFISFLEMHESGVKFNRIDSDISDTLGSKTDENDETQKALNKEIEHVFKTA
                     LGEKVNKLSVEALKNTETPALILVSEESRRMAQMSKMYAKSGMNFPGMFNEEKTLVVNN
                     KNTIIKKLVEVSKDDSKKDEVRTICEHIMDLAKIANKELDANEMDEFIKRSNQLLSRVI
                     "
     PFAM_domain     complement(16537..17004)
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3774_0337"
                     /evalue="5.60E-10"
                     /label="ctg1_3774"
                     /locus_tag="ctg1_3774"
                     /protein_end="183"
                     /protein_start="27"
                     /score="39.8"
                     /tool="antismash"
                     /translation="DIFIREVISNACDAISKFQRLVSLGEANIDKEESYKVTVSINKEN
                     KTLKFIDNGIGMTEEEVKKYITQVAFSGATDFVEKYKDKMDEGKDIIGHFGLGFYSTFM
                     VSDKVQIDTLSYKSEAEAVKWVCNEGGTEYEISTSEERTTRGTTITLYINEE"
     CDS             complement(17235..19013)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:diguanylate cyclase (Score: 109.4; E-value:
                     4.9e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3775"
                     /transl_table=11
                     /translation="MQQVDMLKTYKLFLNNLPWPVWIEGIDSKILYLNKHYEDKFKIKL
                     EEAIGKYSEEVFLPEKVNIYNKNVKECLQSSNVCVVEGIVNGSFIECYIFPIKDDNGHN
                     KAVAGIVMDINDRKEREIYIENQKNILRTIIDAVPESIFYKDTESRFIGYNKKFREFYN
                     KKGVTDIIGKSDIEIYDDKETAVKFIELDKKIISTKKAKYYEDKVKDENGEERIEENIK
                     IPVINDDGEVWGVVGLSRDITERKNMEEKLRYLSQTDILTGTYNRYSFEEKIKELNYEK
                     YLPLGIIMGDVNGLKLVNDTLGHLEGDKLLKNISNILKHICDLQGYVFRWGGDEFIILL
                     PNSGQSKCEAVIRDIRRKCEETESDFIQLSIALGESVKYDLKDDIYNCIKKVEEKVYRQ
                     KLLDKKSIKSSIMESLRKSLEEKNMETNEHAERVQKYALALGEKMKLKISDLDELILVA
                     SLHDIGKIGINEEILLKPGKLTDEEFEIMKTHTEIGYRIINASSELGNVAKSVLTHHEK
                     WDGSGYPLGLKGEEIPLMARIINVVDSYDIMTRDKIYRKAIDKKKAISELKKHAGKQFD
                     PEIVRHFIEYIEDNEV"
     PFAM_domain     complement(17397..17585)
                     /aSDomain="HD_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13487.8"
                     /description="HD domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3775_0342"
                     /evalue="3.00E-18"
                     /label="ctg1_3775"
                     /locus_tag="ctg1_3775"
                     /protein_end="539"
                     /protein_start="476"
                     /score="65.9"
                     /tool="antismash"
                     /translation="GKLTDEEFEIMKTHTEIGYRIINASSELGNVAKSVLTHHEKWDGS
                     GYPLGLKGEEIPLMARII"
     aSDomain        complement(17793..18254)
                     /aSDomain="TIGR00254"
                     /aSTool="tigrfam"
                     /description="GGDEF: diguanylate cyclase (GGDEF) domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3775_0077"
                     /evalue="4.40E-25"
                     /identifier="TIGR00254"
                     /label="ctg1_3775"
                     /locus_tag="ctg1_3775"
                     /protein_end="407"
                     /protein_start="253"
                     /score="86.3"
                     /tool="antismash"
                     /translation="YLSQTDILTGTYNRYSFEEKIKELNYEKYLPLGIIMGDVNGLKLV
                     NDTLGHLEGDKLLKNISNILKHICDLQGYVFRWGGDEFIILLPNSGQSKCEAVIRDIRR
                     KCEETESDFIQLSIALGESVKYDLKDDIYNCIKKVEEKVYRQKLLDKKSI"
     PFAM_domain     complement(17811..18245)
                     /aSDomain="GGDEF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00990.23"
                     /description="Diguanylate cyclase, GGDEF domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3775_0341"
                     /evalue="9.10E-26"
                     /label="ctg1_3775"
                     /locus_tag="ctg1_3775"
                     /protein_end="401"
                     /protein_start="256"
                     /score="90.6"
                     /tool="antismash"
                     /translation="QTDILTGTYNRYSFEEKIKELNYEKYLPLGIIMGDVNGLKLVNDT
                     LGHLEGDKLLKNISNILKHICDLQGYVFRWGGDEFIILLPNSGQSKCEAVIRDIRRKCE
                     ETESDFIQLSIALGESVKYDLKDDIYNCIKKVEEKVYRQKL"
     aSDomain        complement(18258..18635)
                     /aSDomain="TIGR00229"
                     /aSTool="tigrfam"
                     /description="sensory_box: PAS domain S-box protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3775_0079"
                     /evalue="8.90E-12"
                     /identifier="TIGR00229"
                     /label="ctg1_3775"
                     /locus_tag="ctg1_3775"
                     /protein_end="252"
                     /protein_start="126"
                     /score="43.2"
                     /tool="antismash"
                     /translation="QKNILRTIIDAVPESIFYKDTESRFIGYNKKFREFYNKKGVTDII
                     GKSDIEIYDDKETAVKFIELDKKIISTKKAKYYEDKVKDENGEERIEENIKIPVINDDG
                     EVWGVVGLSRDITERKNMEEKL"
     PFAM_domain     complement(18276..18608)
                     /aSDomain="PAS_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08448.12"
                     /description="PAS fold"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3775_0340"
                     /evalue="4.30E-14"
                     /label="ctg1_3775"
                     /locus_tag="ctg1_3775"
                     /protein_end="246"
                     /protein_start="135"
                     /score="52.8"
                     /tool="antismash"
                     /translation="DAVPESIFYKDTESRFIGYNKKFREFYNKKGVTDIIGKSDIEIYD
                     DKETAVKFIELDKKIISTKKAKYYEDKVKDENGEERIEENIKIPVINDDGEVWGVVGLS
                     RDITERK"
     aSDomain        complement(18651..18995)
                     /aSDomain="TIGR00229"
                     /aSTool="tigrfam"
                     /description="sensory_box: PAS domain S-box protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3775_0078"
                     /evalue="1.60E-08"
                     /identifier="TIGR00229"
                     /label="ctg1_3775"
                     /locus_tag="ctg1_3775"
                     /protein_end="121"
                     /protein_start="6"
                     /score="32.7"
                     /tool="antismash"
                     /translation="LKTYKLFLNNLPWPVWIEGIDSKILYLNKHYEDKFKIKLEEAIGK
                     YSEEVFLPEKVNIYNKNVKECLQSSNVCVVEGIVNGSFIECYIFPIKDDNGHNKAVAGI
                     VMDINDRKERE"
     PFAM_domain     complement(18660..18974)
                     /aSDomain="PAS_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08448.12"
                     /description="PAS fold"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3775_0339"
                     /evalue="1.90E-09"
                     /label="ctg1_3775"
                     /locus_tag="ctg1_3775"
                     /protein_end="118"
                     /protein_start="13"
                     /score="37.9"
                     /tool="antismash"
                     /translation="LNNLPWPVWIEGIDSKILYLNKHYEDKFKIKLEEAIGKYSEEVFL
                     PEKVNIYNKNVKECLQSSNVCVVEGIVNGSFIECYIFPIKDDNGHNKAVAGIVMDINDR
                     K"
     CDS             complement(19499..21526)
                     /gene_functions="transport (smcogs) SMCOG1243:ABC
                     transporter, permease component (Score: 317.3; E-value:
                     3.8e-96)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_3776"
                     /transl_table=11
                     /translation="MYFKISLNNVKKSFKDYAIYFLTLTFAVCIFYSFNSIDSQSVMAD
                     MNKGQQEYVKTMGQIISTMSIGVSVILGGLIIYATKFLIDRRKKEFGIYMILGMSKRKM
                     SKILFFETLYMGIVSLLAGLLLGVLFAQILSIFTAKLFAVEMTKYSFVISTSAILKTIL
                     YFGLMYLVVMIFNVIIVSRYKLIDLIRAEKKNEKIKVRNPYLATGILIVSFIALGYAYY
                     LVNKVGLNFLDNKFKLSIILGVIGTAFFFYGIASVTFFILEKNKNFYLNRLNIFSVKQI
                     SSKFNTNFISMTIICLMLFITIGTLASGLTIKNCMESELKNQTPFDASVQVFDRENDNV
                     LSPVNILKQLNYNLDEYSNYTVLNQYVYNMSTRDLLEKYTTTNDQKEILDIRTFDKTNM
                     IKLSEYNNMQKIKGEAPVDLKDDEVLMCSNYEPLKNILNAFMEKENSIKIGDKEFKIKE
                     KKIKTEAFSTSPSSDSLFTLIVPDYVVSGLKSSGEVLNLNFSGDNKVEGKEKLTTILND
                     FRFDGEKYKDLSYGIYGETREMAYDANRGISSIVLFIAVYIGIIFLLASAAVLALQQLS
                     HCNDSIERYRALRKIGATKSMVNKSIFKQVSVFFALPLAVAIVHSYVGINVVNNYLIAL
                     GTGSELNSILVTALIMIIVYGGYLYATYIAYKNVIDNEFN"
     PFAM_domain     complement(20975..21265)
                     /aSDomain="FtsX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02687.23"
                     /description="FtsX-like permease family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3776_0343"
                     /evalue="6.40E-10"
                     /label="ctg1_3776"
                     /locus_tag="ctg1_3776"
                     /protein_end="184"
                     /protein_start="87"
                     /score="39.5"
                     /tool="antismash"
                     /translation="KKEFGIYMILGMSKRKMSKILFFETLYMGIVSLLAGLLLGVLFAQ
                     ILSIFTAKLFAVEMTKYSFVISTSAILKTILYFGLMYLVVMIFNVIIVSRYK"
ORIGIN
        1 taaaggttca aaacattcta atccaatttt cctgaatccc tctactaaca ctcttcttct
       61 tctgttatat tccttcgtca tttctataac actatcatca ccatttttta atgcttctat
      121 agctgcatat tgagcagttg ttggagagca cataattcca tattgatgta ttttcttcat
      181 tgcatcgatt aaaatttgat gtccgcaaac atatccaagt ctccatcctg tcatcgcata
      241 tgatttagaa aatccattta taactaatgt tttttctttc atttctggaa atgatgctat
      301 cgaaacatgc ttatctccat aacaaagttc tgcatatatt tcatcagaaa ttacaatgat
      361 atctttatcc tttaacacct caactattgc tgcaagctca tccctattca taattgcgcc
      421 tgttggattg ttagggaatg ggattattac tacttttgtc ttaggcgtaa tagcttcttc
      481 caaatcctct ggcataagct taaattcatc ttcagcttta aggtttaaaa ctttagcagt
      541 agcacctgta aatgccgtac atcctttata tgctacaaag ctaggttctg gaattataac
      601 ttcatctcct ggacctacta aagctcttag tgctaaatca attccttcac ttccaccaac
      661 tgtaactaat atttcattta atggattata gcttaagtca aatcttctat aaaggtattt
      721 tgaaatttca ttacgtaatt caacaaatcc agcattagaa gaataatgag tatgtccttc
      781 ttctatagaa taaattccag cttctctaac attccaagga gtaacaaaat caggttcccc
      841 aactcctaat gaaattacat cttccatttc atttatcata tcaaaatatt ttcttatgcc
      901 tgatggaggc atttttttta cattatctaa aatcatattt tctaatatca tataaatatt
      961 gcctccctat cgtctacttt cttttcctta aatattgttc catgttcttt atatttcttt
     1021 aatacaaaat gagttgctgt gctaagcaca tattgttgca ctgctaattt ttgtgaaaca
     1081 aaaagtgcaa cttccttcat tgtttttcct tcaataataa cagttaaatc aaatcctcca
     1141 gacattaaat aacaagcttt aacttgtgaa aatttataaa ttctctctgc taccttatca
     1201 aaaccttctc ctctttgagg tgttattttt acttctatta atgcagtaac tgtttcactt
     1261 ccggtatttt cccaatttat aagagttgta taacctgcta ttatactctt ctcttcataa
     1321 tctctaatag cttctctgac ttcttctaca gttttacctg tcatagtagc aatttgttca
     1381 tcgctatacc tactgttttt ttctaatatt tcaagtattt cctccattgc aaatgccctc
     1441 cttattttta taaatgaatg atgaataatt aatatctaga tttaattatc cttataacag
     1501 ttctaaaatt atataatttt atatacataa aaaaagtcct ccatcccaaa caagggacga
     1561 aggaactact tcgcggtacc accctaataa acaatataaa tattgttcac tcagctggag
     1621 tatctaaaac attaatactc cacctctata acgtgaggaa cacgtcatta cctaattaaa
     1681 aattgaacac ataaatgcaa aattactgtt aatccttatt ttttagtaat gaaattcaaa
     1741 ggctgcttct ataaagctta cttactagac ttccaccaaa ctctagctct ctaaaaagtt
     1801 cacttaaata tactattcct tatcactatt tttaaaatat aaaacaataa taattagtta
     1861 taaataaaac aactattaat ttaaactaat tataataaaa aacgtcattg tgcatgcttt
     1921 tataatataa atacttaaat acttaaatac ttaaatactt aaatacttaa atacttattt
     1981 atattataaa ctcaattata taaataattc aatactattt tatatattat tttaacatat
     2041 taataatcaa ctcataaatt tataaactta aaataaaatt tataaattta aagagagtca
     2101 taagttttgt ctcttataac tctctattaa acaactaata attataattc attatctatg
     2161 ctgttgtttt ttagctcttc tacatgctgg gcatctcact ggctcatttt caaagccttt
     2221 ttccttataa aattcttgtt ctcctactgt gaaaataaat tcttctccac aatctttaca
     2281 tactattttt ttgtcttcca ttttaatgtt ctattgccaa agtataataa ctttgcaaca
     2341 gttcacctcc tcttttaact taaagttttc actttaatat taatagtatc ccttaatctt
     2401 caataaatat tcatttttat aatttatttt tcaactacaa gtttaaattc ttcatcctca
     2461 agttttatag aacagtttcc accctcgctt aatttaccaa acaaaatttc atcaactaat
     2521 agtggtttta tcttagagct tattattcta gcaatctccc tagctccaaa ttcctgtgat
     2581 gttcctattt ttgctacatg actaatacac tcatcattaa agttaatttt tattttctta
     2641 gccgcaagct tatttttaaa gtcatttaat tgttttttag caatatctaa tgccatagaa
     2701 tcattcatac tgttaaatac aactatcttg tctaatctgt ttctaaattc aggactaaag
     2761 aacttcttaa cttcttccat tatagcttca cctttaactt ctctatcacc aaaacctata
     2821 agtctcttac ctatatttct tgcaccagca tttgaagtca ttattattat tgcatttcta
     2881 aaatcagctt ttctaccttt attatctgtc agagtagcat aatccattac ttgaagtagt
     2941 acactcaaaa tatcttgatg tgctttttca atttcatcaa gcaataatac acagtgaggt
     3001 ttttttctta tagaatctgt aagtaatccg ccctcttcat atccgacata tcctggaggt
     3061 gatcctataa gctttgaagc tgcatgtttt tcagcatatt cactcatatc aaatctaata
     3121 agttctatgc ccatcttttt agcaagacat cttgcgattt cagttttacc aactcctgta
     3181 gggccaacaa atagcattga tgctactggt ttatcttctt cattcaatcc tgatctagac
     3241 atttttatgc atcttacaac ttcttcaatt gcattatcct ggtggaatat attttctttt
     3301 aaatctgctt caagatgttt taacgaactt atttcactgc tttccactgt ttgctttgga
     3361 atactacata ccttagatat tatttcttca atgatttttt catcaactat aattttctca
     3421 tctaaatttt cgttatgcat acgtgcataa gcacctgctt catcaattat atcaacagct
     3481 ttatcaggta aatatttatc attaatatat ttatcactta attttactgc atctgcaatt
     3541 gcttcatctg tataacttac attatgatat tcttcataat tcctcttaag tccatttaag
     3601 atttgtatag cttcattaat agacggttct ttcacatcta tagtttgaaa tctccttgtt
     3661 aatgctttat ctttttcaaa gaattttttg tattcttcaa aagtagttgc tccaataaat
     3721 ttaatctttc catcagttaa atatggtttt aacaaattag atgcatctaa tgctccacca
     3781 ttcaacgatc cagcaccaac tatgttatga atttcatcaa tataaactat aggcttgtgc
     3841 tcttttccta ttaaatctaa aatcctcttt attctttcct caaagtctcc tctatatttt
     3901 gtaccagcaa ttactgatcc aatatctagc gaaaacatag aacttccctt taatttctca
     3961 ggaacttttc cttcactaat aagctttgct agtcctaaag taatcgctgt ttttccaaca
     4021 cctgattccc ctacatggat aggattattt tttatccttc tgcaaagtat ttgaatactt
     4081 ctttctagga tatcttctcg tcctattaaa ggatcacaat gttcttcttt tgctttttct
     4141 atcagattaa ctgtgaattt gtgtaaaaac gcatcttctt ttttcttttt agtcttttct
     4201 tcactattaa taggttctga tggaatctct tcttcttcaa gatcttcatg agtttcttca
     4261 tcatactctg atatttcttc ttcattactc gtatctgctt catggcataa caaatataat
     4321 aaatctcttc tattaacccc ttcttgctgc aaatagtata gagcatagct attctccaag
     4381 ttaaacattg cagaaagtat atgatctact cctatagctt cttttccgct gtatttaatc
     4441 tgttcattag ctgttaaaat aactctctga aactctatac tctcttgtgg ctcaccattt
     4501 cttgttgtat tcacatatgt ctttatatat gttttcagat tatatcgtaa attttcaata
     4561 cttccaccac attccttaat tgcatgttct acattttcat caaatgttgc tgcatatagt
     4621 aaatgctcag gtgtaatata ttccgaattc ctttcctttg cctcttcata agctttaagt
     4681 aatatgttgt taacctcatc tgtaattttc atactctaca cctcctctac agtaagctta
     4741 aatggaaatc cttgttcctt tgctaaagac atagcattag caacttttgt cattgctata
     4801 tcatagctat agattccagc tataccattt cctttttgat gcacatccag cattattttt
     4861 tctgcttcta ttaaattttt attaaatact gatactaata tattaataac aaattccatg
     4921 gtagtataat catcattata cataaccact ttgtaatttt taggtttctt tatctttact
     4981 ttatcttttt gctttgttgc aatgttagtt tccataatat attacttcat cactccttgt
     5041 actttaatat cgactatata tattatttta aatagctaca ttttatcaca atattaaaat
     5101 tcataccaat gaatttatgt ttaaagcaca ttcaaaaaaa taacacttcc atatatcaaa
     5161 cccatttttc atcatgctgc attaggagat ttctctaata gccagctatg aaacaaatcc
     5221 acttctttgc ttgatgaaaa ataatcataa aattttggac ttgttatttt ctttcatgtg
     5281 tctaaactaa ttttactaca cttatttcgt tattttccac acctattata cttcttttat
     5341 ttacaatata atcctttatt atatctatcg cttcttctga tataatttca cctggacata
     5401 ttaaaggtat tcctggtgga tatggaatta ttgattcttt tgcaatttta tttttgcatt
     5461 tatcaacttc acacaattca ctatctaaac taaacacttc atgcggctca aatttctttt
     5521 ctggaatagt attataatat tttgaccctg aatctccagc tatattctct atatctaaat
     5581 ctaatattgc tttgtatatc ttataaaaat catcatctgt attaacagga gataatatca
     5641 aaacaacacc tcttgaaaaa ctcatttctg cttgtatttt tttacttctt agataatcaa
     5701 gaaatttatg tccgctataa ccttctggca atattaatac atatctagac aaatcaatat
     5761 catattgttc aaatttatta tttctcttat ccttatattg tttatttaaa tcgaatttat
     5821 ttaatatatg aaccttgcat gtagattcca ttttctcttt ccaaatttct gctctatcta
     5881 ttaacttttc ataattttta tcaccgtaat tatccaaata atatctagca taatctaatg
     5941 atcccattat taaatacgat ggtgatgttg tcataaaagt ttttaaataa aattctaaca
     6001 tgctattttc ttcattacct aaaaggtatg acccctgtgt taaagctggt aaagttttat
     6061 gtgcacttaa aaccacataa tcccctaaac ttgaaactga ttttggcaat ctcttattta
     6121 ttccaaaatg agctccatga gcgcaatcaa taattgtttt taatcctttt ttctttaaat
     6181 ccaatattat ttcttcaata tcatatgtaa ttccaaaata gtttggataa gttaatataa
     6241 tcccttttac attcttacaa cagcttaatg ctttatatat attttctcta ttaggtggaa
     6301 gaaaaactcc attttcgtta tcaataatag gctcaatata cttaactttt aattttctta
     6361 agataagtcc attatagatt gatttatgac aatttctttc aactaaaatc tcatcccctt
     6421 cattaaaagc tgaaaatatc gctgccaagt ttcctgaaga acttccatta actaaaaaat
     6481 atgctttttt agcattgtaa gttttagcca acaattcttg tgcttctttt ataacacctt
     6541 ctggacaatg tagattatct aggggatcaa cttctgttat atctaaaaag cctaatcttt
     6601 taacaaactc ttctccaatt tcatttccta aaaatgcgct tccacattta tttcctggca
     6661 ttgaaagaag taaatttttt tcatcatgat atttaagtaa ttcttctaac aatggtaact
     6721 tcaaaaatac ctctcctatc taaagtttag tttatataaa cgaaatatac ataaccaact
     6781 tgtaacttag atttatgtag ccactcacgg aaatcataga tatttgtttc atcggactta
     6841 tgaaattttt gatggaacat acaatcttaa aaccatctat taaaattttc agtaaccgaa
     6901 acaaatgcat gctccctatt tcggttaact attacataac tctaaacccc aagttgttta
     6961 tctacatctt ctttaaatct tcaataaatt ttaaaacact agattcatca gttgcccatg
     7021 atgttactaa tctaatcgca gcatattttt catcaataac tctttcaata ttaaatgaat
     7081 aattttcact taatttcttg attatatcat taggcaaaat aggaaattgt tgatttgtag
     7141 atgaatctgt caaaaattca tatccctttt ctttcaaggc attttttaat aaaatagcca
     7201 tgttattagc atgttttgca agttcaaaga ataaatcatc tttaaacaat tcttcaaatt
     7261 gaattccgag caatcttcct tttgcaagca atcccccttt ttgctttata gaatatctaa
     7321 aatcttcttt taaagaatta ttacatataa caagtgcctc tccaaaaaga gctccatttt
     7381 ttgttccgcc aatataaaaa gcatctacta aattagctat atcacataat gtcaaatcat
     7441 tttcttctga taaaagtgca gatcctaaac gtgcaccatc taaatataaa agtaagttat
     7501 ttcttttaca acacttatgt aactcttcta attctaattt tgtatataaa gttccaagct
     7561 ctgtagaatt tgatatatat actaacttag gttgaaccat atgttcatcc gtatgagcat
     7621 ctacaacctt ttgaattaaa tcagatgtaa gttttccatc attagttttc atagtaataa
     7681 ccttgtgtcc tgtagattca atagcacctg tttcatggca attgatatga gacgtatctg
     7741 ctcctattgc tgcttgatgt ggtcttaaga aagcagatat tgcagtaaga ttcacttgtg
     7801 ttccacctac tagcaaatgt atatctacat catcacgatc aattttcctt tttaataagt
     7861 ctatagcttt ctgagtatag cagtctgtgc tgtacccttc tgtctgctct aaatttgttt
     7921 ctactagcgc atttaatatt cttgaatgcg ccccttcact ataatcattt ctaaaactgt
     7981 acataatata acctccacct atgttattaa tttttttaaa cattaatcca tctaactcta
     8041 ataaagaata cttcatataa atatctaaca tagaacttaa atttatgtaa taactaatca
     8101 aaatcaaata ctattttcaa cttgaatctc tataaggcag atgtaattag ctaagatttc
     8161 acactgaata aaatcttata aattcatact tttaacaatt atttatagtc atgaaattta
     8221 ctttattccc attctatata aataaacaaa ctacggacta tatgtatgtt ttaaatgtat
     8281 atctaaacta gaaatagagg tcatgctttt gtgtagtgtt acctcaaaat tttcagtaac
     8341 cgaaacaaaa gcatgacctc tatttcggtt agttatcaca taacttcaaa ttccaagttg
     8401 tttatctaca acacatatat tttatgaaca cacttcaatt atttgtattg ataaattttt
     8461 taatactttt tttccaactt caaatatcat ttcctctgtc aattcatcta atccattaat
     8521 ttcatcaata tatattttat agtctccaaa catagaatca tatgtagcta actcttttgc
     8581 taacactatg ctttgttctt ctctaaacaa tctctttaat ttaaaacttt ttattaattg
     8641 ttccatttgc attctatcta tatgatactg tgataattcc acttttccta tgcattcctt
     8701 aattaaactt atagctttat ctacattttc cttagctgtg ttaaaagtta tcttatataa
     8761 ttttatataa ttttcatttg caattttagt aatcacatca tatataagtc cattctcagt
     8821 cctaagtata tcataaagaa gtgaattaac tccttcacca aaatattgat tgaaaattct
     8881 aaggcttttc atttctatac tagttaggtt atctattgga catattattt caaccctaca
     8941 tgttttgatg ccatttcttt tattattaag tacttctact ttgggatatt catattcgat
     9001 tttcttacaa ttcaatttat tgcttccatc atttttatcc aactttactt tccattgacc
     9061 aaaatactta tttataatat atttaacttt ttcaaattct cttgatgaaa ttaccacaat
     9121 agaagtattt tgtgggaaat aatatttatt ataaaatttc tttatatcac ttaatgtcat
     9181 actctctaaa ctattcttag ttcctataat tgggtacttt attcttctac tattaaaaca
     9241 attaaaaaac agtttatctt cacaatattg ctctaattct tcatcccatt cttcaagttc
     9301 ttgttttatt acatccattt cttctttaaa accatcatct ccaaaagtag gattaataat
     9361 tatatctgat aataattcta aacctttttc taaatctggt ccaagcaagg tcccataata
     9421 aatcacatat ggataatttg tcatagcatt gttaaatcca aaaacattag ttaaatcttc
     9481 atttatttgt ttctccgttc tatttctagt tcccttatac accatatgtt cagttgcgtg
     9541 agctacacca tacttttcat tttcaactcc tgcacctgca tctattgata tgcaaattga
     9601 tgtaagttct gaatcagtat gcttatatat taatttaaaa ttattttcaa aaatatattc
     9661 ttgcaattat tttccctccc tacaaatttt ataatttatt tatctgtgat aggcaactct
     9721 tgattgaatg taccttatac attgaaatat atatcatact agaaagaact ggtagtcttt
     9781 tgtgcagtat tgcattgaga atatggttgc aggtatttct acagtagaag ttgttccatt
     9841 ttaatttgtc caaattttac acttggacaa attaaaatgg gtgcaactcc tactgttaga
     9901 aatccgcagc catattctct agcaatcaag caacagacta ccagttcttt cggtaagctt
     9961 ttacatatat ctaaattaca acttgcctat ttgtatacaa ctatttctct acagctttta
    10021 atgcaatagc acattcaatt ctcttctttt gcattttaca tccaatttca tatggaatat
    10081 tcatatcacc attgaaatta aagttatttg cttggcatcc accactacag tagaatttag
    10141 cccaacattc tctacactta ggtttattat atatatgaga ttttttaaac ttcttagcaa
    10201 gatcagtatc atatgtatca tcataaatgc tgcctaactt aaattcttct tttccaacaa
    10261 attgatgaca tgggtatact tctccttgtg gagttattgc tacatattca aatccagcac
    10321 cacagcctga aattctctta taaacacatg gtccaccttg aagatctata ttaaagtgat
    10381 agaatttaaa ttcatcattt ccttctcttt ttcttgttgc catttcttca tataacttat
    10441 catagttatc aaatattgta tcaatatcac tttctctaag agcaagtgga tgtccatctt
    10501 ctaaaacaac aggctctata gataattccc taaaaccttc attaaccata gccatcacat
    10561 cttgataaaa atcagtattt tctcttgtga aagtccctct tacatagtaa gtctttcctg
    10621 gtgttcttct cttaatcatt tctttaatat taggaactat atcatcataa gaaccactct
    10681 tatcaggttt aattctaaca ttatcattaa cttcttttct accatctaaa gaaagaatta
    10741 tatttcccat ttctttatcc atataatcca tcatttcagg agttaaaagg gtagcattag
    10801 tagtcatagt aaatctaatt ctcttacccc atttttcttc attatctctt gcatacgcaa
    10861 ttatttcttt tatagtatcc atgattaaag ttggttctcc accaaataaa tcaatttcta
    10921 tattttttct tggaccactt ctcttaatta cgtaatcaat agctttttta gcagtatcag
    10981 cactcatgac accaccatgt ccatgatatt caccttcatc tgcgaagcaa tatttacatc
    11041 ttaagttaca tccatgaatt acatttaaac aaatagcctt tatataatct ctatcttcca
    11101 tagaactatg agctatatct tcatattgat cttctgaata tagaattcca tcctcagcta
    11161 attcttgaat ttcatcataa gcttctgaaa gttcttcttc atcatacttg cctttaagac
    11221 tttccaatat ttctttttta tttcttaatt tatcatcatc taatatgtca tagactaatt
    11281 cgtctactac atgaactgca ccagtattta catctaaaac aaaataattt tcgccttgtt
    11341 tgaatttatg tatcaaagcc aatttaaatt cctcctaata tacaaagtaa gcagcaacta
    11401 tatagttact gctcgaaaaa ttagttttcg cactctaagt ttgcaactgt acaagatgtt
    11461 ttacaagctg attgacatga gtttgcacat tccttacatc ctggtttaca taaactattc
    11521 ttaatatttg gtttgtttat agtttttatg tgtttcatta caaaaaccct ccatttttaa
    11581 atatactaga taattatagc ataatatcca tcactattaa agaattagtg ctatctcttt
    11641 ttatcaaata tagacacaaa ttattcattt ttataaataa accatacaaa aataaatact
    11701 tgctaaatag tactaaaaat agctgcacat atgtgtatct aaatttttca tactataaaa
    11761 caagtattta ttatactctt ataaatcttt ccctaatatt aacataccta tattattgtg
    11821 tagttagaat tacaattaat tgaattaatt ataaatgtgt aatctgaatt atattaattt
    11881 caaatatctg tttttaatct ttaagcatat ataatactat aaatatgtca taaccacagt
    11941 tgatttaata ttatttaccc cttaggcttt taattaacac ctatgcgtaa attatatcta
    12001 catttcttct atttgtatat tatactaaag tatacttttt aataacatag agcatatttt
    12061 taaaaataac taatccatct gccaagccca tttttcataa tgacacttta gacttgttat
    12121 tttctttcat gtgcctaaaa gaaactaata gaactatatt atgccctttt cttttaaaat
    12181 atttaatgca gttgttttat tttttacttc tagtttagaa taaacagctg caatatgctt
    12241 ctttactgta atcaaagcaa tatttagttt ttcagaaatc tcactttgct tatatccttt
    12301 attcactaaa ttcattactt cactttctct tggtgttaat tctatttttt catcatcact
    12361 ataatttttc atgtacatat agttaaactt ttcacaatta ggcagcaaaa ctttcacata
    12421 ttcctcttct ttttctatat gtctcaaaat aggtaatata tacggtgcta actctgcaaa
    12481 acacattaca acatgatcct ctttagcata cgatatagct ttcattaatg aatctttagc
    12541 tttttcaatc ccgtatagat tatattttgc aattgagtca aatatatatg aatatataat
    12601 tccaaacata ccatttttat ttttacaaac ttctaacatt gtttctgctt gaacttctaa
    12661 ttcaatatag ctttctttaa gcatcatagc taatgctgat acaatatatc tcaaagttat
    12721 aaccggtgaa atattttgca tcttaggtct ttcataattt ttaacacatt tatttatttc
    12781 ttctaaattt ccagtaattc catatatata tcccataggt atttcttcac cttttagaaa
    12841 actcggaata ttaagttttt gatattcctt aattaatatt tctagcttac ttgtagcctc
    12901 acgtctatta tttttattca aacaaatcct catcaaaagg aaaagtgaac aaattataat
    12961 acttgtctgt ttttttattt ttgctttatg taatgcttta tacgcaaaca attctgcctc
    13021 atctacattt ccagtttcaa aaagatattc tgcttttatt aaataatttg atcctgtagc
    13081 tccaccgtta gatatgcgaa tgaaatactt tattcctttt tcaaaacact ctgctgattc
    13141 ttttaatttt ccccgttccc tataatataa gcataaaaaa tgtggagatc caaaagtaac
    13201 tggcatctta tcatttgcta tcttagaagt tcccccatta aaaaattcat aagctttctt
    13261 atgatactca atcatctttt ctacatcatt catgcttaaa agactctcca agaatgcaat
    13321 ttcacccagc acttggttct tatctttaag attttcatct ttctcataga tagattttgc
    13381 ttcatataga cgttccctag caatcacacc attcccataa agtatgtaaa aaaataaata
    13441 tgttaaataa gctacaggcc tatttatttt ttcgttaata tttaattcgt caaaaactga
    13501 atttataatt ctttgccata ggctggtaag atctattgta taatttcttt ccattaaatc
    13561 aagaacgcgc ttaaagttct ttgctttata ataatatttt attgcttgta tatcttcgtt
    13621 attttttgaa taccaatcac cgcttgcatt atttacttta ttaaaatcta tattagaata
    13681 taaaagttct tcttgtaatg cactctttaa aatagaatgc attgtatata gcttcgattt
    13741 cgaatcatat cttataaaac agttatttga gattaaattt ttaattatta acctgcattt
    13801 ttgatttcca gtaatatata tagcttgctc taatgtaaag ttctcaacta atgcaagttt
    13861 taaaagtatt tcttttgttg tttcatcaaa cttatcatac gcagcaattt taatcaattc
    13921 cgtcgctttt ggtatatcat caaaagtatt ttcattatga tattgaagta atgcaagata
    13981 agtagcagat ggccatccac ccgtatattc atatacttct tttttttctt tatagcttaa
    14041 ttttattcca ttaagtttaa agaattctac agtttcttca aatgtaaatg atatatcatc
    14101 ctgccacatt attatgcatt tttgctttaa ttcaagctca atatattcat ttgatggtct
    14161 attacgactt attataacaa tatgtaaatt aaatatttct tctaaacata tagtttttaa
    14221 aaaatcatta atatattcat tttctttatc ataccagtca tcgataacta taacagtttt
    14281 ttgcttcaat tcatccttta ttatatctat aatttcatag acataattat catttttagg
    14341 gaatccatac tcactaagtc tctcactaag acttaaattt gagcttttaa ttgatttaca
    14401 aaatttatac cacatccaaa tatcatcgtt ctttttatta cctacatcaa accaaatagt
    14461 ttgtatttct tttttatttt ccaaaaaatt tcttactgaa gttgttttac catatcccat
    14521 gggtgctgaa ataaaaaaca caggcacctc aaaaatttga gataacatac tagtaatacg
    14581 ctttctatgt actaatttag gcctaaagat tcctttcgtc ataaataatt atcaccctta
    14641 atataaatca ttatgcttag taacataatt aaatttttat gtttataaac taccatacta
    14701 ttccaaataa tactacacat tttaatatta atatacatat tatatagttt tctaaattac
    14761 ataccaatac tttaccacac ctaatactca acttcaaacc tttcttttgt ataatttaac
    14821 tgttcatatt aaagtcttta tatgatatac gaatagcaat tccagcttca tcaaatttat
    14881 agtttgtact attaattgaa cttttattat taacttaatt catacctaca gtataaaagg
    14941 cttctgccat ctcgctagaa tctttgttaa ttcttattca cttctaaaaa aataaaaata
    15001 gtcttcaaca ttaaagacaa gttaatgttg aagactactt ataatgtata attttactat
    15061 tgtgttttaa gacacatgaa agaaaatatc aggttcaaaa tatcatgatt ttttttaaat
    15121 gtgcgtaaat attatccgca aaaaattcta taattcaata actctactta aaagttgatt
    15181 acttctcttt ataaactcat ccatttcatt tgcatccaat tccttattag ctattttagc
    15241 taaatccata atatgttcac aaattgtcct aacttcatct tttttagaat catccttaga
    15301 aacttctaca agcttcttaa ttatagtatt tttattattt actactaaag ttttttcttc
    15361 attgaacatt cctggaaaat tcattcctga ttttgcatac atcttgctca tttgagccat
    15421 tcttcttgat tcttctgaaa ctaaaataag tgctggtgtt tctgtatttt tcaatgcttc
    15481 aactgataat ttattaacct tttcaccaag agcagtctta aatacatgtt ctatttcctt
    15541 atttaatgct ttttgagttt catcattttc atcagtcttt gatcctaaag tatctgaaat
    15601 atcagaatca attctattaa atttcactcc tgattcatgc atttctaaaa atgaaataaa
    15661 atgatcatct aaactacaat tcaatatcac tgcatccaaa tcatattctt taaacatttt
    15721 aatatattga gattgttgtt tttcatcatt gacataaaat actttatttt catgcttttc
    15781 tttgttagct tcaagataat cttttaatgt tacaaactcg tcttttaagt ttttaaagat
    15841 tattatatct ttaatttttt catagaattt ttgatctctt aaacaaccat atttaataaa
    15901 tatttgtata tctggccaaa acttattaaa ttcttctcta ctatttttaa ataagtcaac
    15961 taatttatct gcaacctttt taattatatg gttagaaatc ttagaaactt ctttatcatt
    16021 ttgaaggaaa cttcttgata catttagagg taaatccgga caatctatag ttccctttag
    16081 taataataag aaatctggaa ttacttcttt tatattatct gcaacaaaca cttgattatt
    16141 ataaagtttt acttgccctt ctgttgcttc aaattcatga gttaatttag gaaaatataa
    16201 tattcctttt aaattaaatg gataatcaac atttaaatga atccaaaata atggttcatt
    16261 aaaatccata aatacttttc tgtaaaaatc tttatattct tcatcagtac aatctttagg
    16321 tgctttaatc cataaaggct ttgtatcgtt caaaggtttt ggtgcttctg gctctactaa
    16381 ttcttgatat tcagtaccat cttccttttt ctttgttaca tatttaggtt cttcttttgg
    16441 tttattttca tcttctaaat atatttctgt aggtaaaaat gaacaatact tctttattat
    16501 ttctctaact ttatattctt ctaagaactc tttactttct tcattaatat ataatgttat
    16561 agttgtccct cttgtagttc tctcttcaga cgtagatatt tcatactcag tgccaccttc
    16621 attacaaacc cattttactg cttcagcttc acttttatat gataatgtat ctatttgaac
    16681 tttgtcagaa accatgaatg ttgaataaaa tccaagacca aaatgaccta ttatatcctt
    16741 accttcatcc attttatctt tatatttttc cacaaaatct gttgctcctg agaaagcaac
    16801 ttgagtaatg tattttttta cttcttcttc agtcattcca ataccattat ctataaattt
    16861 caaagtttta ttttccttat ttatagatac agtcacttta tacgattcct ctttatctat
    16921 attagcttcg cctaaagaaa ctagtctttg aaacttactt attgcatcac atgcattact
    16981 tataacttct ctaataaaaa tgtctttgtc agagtatagc catttcttaa taatgggaaa
    17041 tatattctct gtatcaattg aaatattacc attttctttt atcattataa ccactcctct
    17101 tatttttcta gaaaatattt tagcctaaca tatgctaatt gtcaaattgt tctttaaata
    17161 gtttaacaat ggatacttac atcattgtat ataataatct atatacttag catgtcttat
    17221 tataaagata cagtttatac ttcattatct tcaatatact ctatgaaatg tctaactatt
    17281 tctggatcaa attgctttcc tgcatgtttt ttcaattcac ttatggcttt ctttttatca
    17341 atcgcttttc tatagatctt atcccgagtc ataatatcat aggaatctac tacgtttatt
    17401 attcttgcca ttaatggtat ttcttcacct tttaaaccta aaggatatcc acttccatcc
    17461 catttttcat gatgtgttaa tacgctctta gctacatttc caagttcact agacgcatta
    17521 atgattctat atccaatttc tgtatgagtc ttcattattt caaactcttc atctgtaagc
    17581 tttccaggct ttaatagaat ctcttcatta attcctatct ttcctatatc atgaagactt
    17641 gctactaaaa ttaattcatc taaatctgaa atttttagtt tcattttttc ccctaaagct
    17701 agagcatatt tttgtactcg ttcagcatgt tcattagtct ccatattctt ttcttctaaa
    17761 ctttttctaa gggattccat aattgaactt ttgatactct ttttatccaa tagcttctga
    17821 cgatatacct tttcttctac cttcttaata caattgtata tatcatcttt caaatcatat
    17881 ttcacgcttt ccccaagtgc tatacttaat tgtatgaaat ctgattccgt ttcttcacat
    17941 ttccttcgaa tatctctaat aactgcttca catttagatt ggccactatt tggtaacaga
    18001 attataaatt catctccccc ccatctaaat acatatcctt gtaaatcaca tatgtgtttt
    18061 aatatattag atatattttt taataattta tcgccttcca aatggcctaa tgtatcatta
    18121 actaacttaa gaccattaac atctcccata attattccca atggaagata cttttcatag
    18181 tttaattctt taatcttttc ttcaaagcta tatctattat atgttcctgt aagtatatca
    18241 gtttggctta gatatcttaa cttttcttcc atgttctttc tttcagttat atctctagat
    18301 aatccaacta ccccccaaac ttctccatca tcatttatga caggtatctt aatattttct
    18361 tctattcttt cttccccatt ttcatccttc accttatctt catagtattt agctttcttc
    18421 gtactaataa tttttttatc tagttctata aattttactg ccgtttcctt atcgtcatat
    18481 atttctatat cgcttttccc aattatatca gttacgcctt ttttattata aaattcccta
    18541 aacttcttat tatatcctat aaatctactt tctgtatctt tataaaaaat ggattctggc
    18601 actgcatcta ttattgttct caatatattc ttttgatttt ctatataaat ttctctttct
    18661 tttctatcat ttatatccat aacgatgcct gctaccgctt tattatggcc attatcatct
    18721 tttatgggga atatataaca ttcaataaat gagccgttca ctattccttc tactacacat
    18781 acatttgaac tttgcaaaca ctcttttaca tttttgttat atatgttaac tttttctggc
    18841 aaaaaaactt cttcactata ttttccaatg gcctcttcta attttatctt aaacttatct
    18901 tcataatgtt tgtttagata taatatttta gagtcaattc cttcaatcca aactggccaa
    18961 ggcaaattat ttaaaaataa cttatatgtt tttaacatat caacttgttg cataacttaa
    19021 ctttcccctt tatttctgat tatatcactt atatataatt ttactattta ttaactaaaa
    19081 cgtctactaa agtaaataca tccatataac taacattatt ttcaattata taatttttta
    19141 atttacttgt tacatattac aaacttaaaa tacaaattag gtacctgtta tgttaaaatt
    19201 cattaatatt tttaacaata acataattat aagcttaaat ttatttttca atatagaata
    19261 tattataaat aaaaataaat cgactatata gatacccaat atatctacat agccgattta
    19321 taatacggta tataaagtaa aataacaatt ccaaatctaa catgaatatt tttcatcaga
    19381 taattaagca aagtgccatc atagtaaatc tattgtagta ttttaccgac gctagatcat
    19441 gaaaaatatt ctgacagatg gacttgttat cttttaatgt tcctactaac ctatattttt
    19501 aattaaattc attatcaata acattcttat acgctatata tgttgcatat aaatatccac
    19561 cataaactat aatcattatt aaggctgtca ctaatataga atttaattca cttcctgttc
    19621 ctaatgcaat tagataattg tttaccacat tgattccaac atatgaatga actatcgcaa
    19681 ctgctaaagg taatgcaaaa aacactgata cctgcttaaa tatacttttg ttgaccatac
    19741 ttttggttgc accaattttt cttaatgctc tatatctctc tattgaatca ttacaatgag
    19801 ataattgctg tagtgcaagc actgctgcac ttgctaataa gaatattatt cctatataaa
    19861 cagctataaa taatactatt gatgatattc ctctattagc atcatatgcc atttccctag
    19921 tttcaccata gataccataa ctcaaatcct tatatttttc tccatcaaat ctaaaatcat
    19981 ttaatatagt agttaatttt tctttacctt ctactttatt atcaccagaa aaattcaaat
    20041 tcagtacttc tcctgatgat tttaatccac ttaccacata atctgggact attaaagtaa
    20101 ataaactatc acttgaaggt gatgttgaaa aagcttcagt tttaattttc ttttccttta
    20161 ttttaaattc cttatcacct atttttattg aattttcttt ttccataaat gcatttaaaa
    20221 tattctttag tggttcataa ttagaacaca tcaatacttc atcatctttt aaatctacgg
    20281 gtgcttcacc ttttatcttt tgcatattat tatactcaga taatttaatc atattggttt
    20341 tatcaaatgt tctaatatct aaaatttctt tttgatcatt agttgttgta tatttttcta
    20401 ataaatctct agtactcata ttatatacat attgattaag tacagtataa tttgaatatt
    20461 catccaagtt ataatttaat tgttttagta tattaactgg tgaaagtaca ttatcatttt
    20521 ccctgtcaaa cacttgaaca gatgcatcaa atggtgtctg attttttaat tcagattcca
    20581 tgcaattttt aatagtaagt ccacttgcta aagttcctat tgttataaac aacattaagc
    20641 agataattgt catggaaatg aagttagtat taaatttact tgaaatctgt ttaacactga
    20701 agatatttaa tctatttaaa tagaaatttt tgttcttctc aagtataaaa aatgtaaccg
    20761 aggcaattcc ataaaagaaa aatgctgttc ctataacccc aagtataatt gacaatttaa
    20821 atttattatc taaaaaattt aaaccaacct tatttactaa gtaatatgca tatcccaacg
    20881 caataaacga aacaattaat attcctgttg ctaaataagg atttctaact tttatttttt
    20941 catttttctt ctctgcacga ataagatcaa ttaatttgta ccttgaaaca ataattacat
    21001 taaatatcat gactactaag tacattagac caaaatataa aattgttttt aagattgcac
    21061 tagtcgaaat aacaaaacta tatttggtca tttcaactgc aaaaagttta gctgtaaata
    21121 ttgataatat ttgcgcaaat aatactccca gtaaaagtcc tgctaataat gatacaattc
    21181 ccatgtataa tgtttcaaaa aataatattt ttgacatctt tcttttagac atgcctaaaa
    21241 tcatatatat accaaattct ttttttcttc tatcaatcaa aaatttagtt gcatatatta
    21301 ttaatcctcc aagaattaca gatacaccaa tagacatagt tgaaattatt tgtcccatag
    21361 tcttaacata ttcctgctga cctttattca tatctgccat aacggattgt gaatcaattg
    21421 aattaaaact atagaatata cacactgcaa atgttaatgt taaaaaataa atagcataat
    21481 ccttgaaact tttctttaca ttatttaacg atatcttaaa atacatcttt agagtcacct
    21541 ccaagaagag taacaaca
//
