LOCUS       NC_022571.1            20200 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_022571.1 Clostridium saccharobutylicum DSM 13864, complete
            sequence.
ACCESSION   NC_022571
VERSION     NC_022571.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:03:18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 953195
            Orig. end    :: 973395
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..372
                     /gene_functions="regulatory (smcogs) SMCOG1136:GntR family
                     transcriptional regulator (Score: 75.8; E-value: 6.4e-23)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_787"
                     /transl_table=11
                     /translation="LKILISNKSDLPIYEQIKAQIKEQILSGRIPENEFLPSIRQLAKD
                     LGISVITTTRAYSDLESEGFIATVRGKGSYVLPKDNEMVREQYLKEIEDAFMIAIEKSK
                     LANISKDELILILKNLIEE"
     protocluster    1..20200
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[962877:963432](+)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9683..10237
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..20200
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20200
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="5"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     PFAM_domain     40..228
                     /aSDomain="GntR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00392.23"
                     /description="Bacterial regulatory proteins, gntR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_787_0086"
                     /evalue="4.30E-15"
                     /label="ctg1_787"
                     /locus_tag="ctg1_787"
                     /protein_end="76"
                     /protein_start="13"
                     /score="55.2"
                     /tool="antismash"
                     /translation="YEQIKAQIKEQILSGRIPENEFLPSIRQLAKDLGISVITTTRAYS
                     DLESEGFIATVRGKGSYV"
     CDS             378..1235
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 130.7; E-value:
                     1.2e-39)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_788"
                     /transl_table=11
                     /translation="MNALEIKNLNKDLNGFNIKNINLELPKGYILGYIGQNGAGKTSTI
                     KLIMNQLKRDTGEIRVFGKQYEDDEAEYKDMIGFIGDECYFPTCFTLKDVINTLKDFYS
                     SFDEVKFNEYAERWALPYKKKIKDFSKGMKAKLSFASVLSRDTKLLLLDEPTSGLDPVV
                     RNEILEILQEYISDGERSVIFSTHIVSDLEKITDYLYFINNGEKVFHDTTENILESHLV
                     VKGGTDDLTNELKEKLLGYKSSNIGFEGLINLEDKKYLDDNLLFEKPSIDDIIVFYINA
                     ARKN"
     PFAM_domain     429..848
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_788_0087"
                     /evalue="3.00E-20"
                     /label="ctg1_788"
                     /locus_tag="ctg1_788"
                     /protein_end="157"
                     /protein_start="17"
                     /score="73.2"
                     /tool="antismash"
                     /translation="IKNINLELPKGYILGYIGQNGAGKTSTIKLIMNQLKRDTGEIRVF
                     GKQYEDDEAEYKDMIGFIGDECYFPTCFTLKDVINTLKDFYSSFDEVKFNEYAERWALP
                     YKKKIKDFSKGMKAKLSFASVLSRDTKLLLLDEPTS"
     CDS             1309..1515
                     /locus_tag="ctg1_789"
                     /transl_table=11
                     /translation="MKTILSYLKLDLRISKRSLLCVAPALIFSAYMFFEKNVYILGCSI
                     ITLIIMGYISYLISCRICRRKEV"
     CDS             1520..2173
                     /locus_tag="ctg1_790"
                     /transl_table=11
                     /translation="MKDSINYLKFDLRITKESTKFQILIIALFYIIFMFFKHAYVFGMS
                     YLFFLLIIFSRIPFSLQGNEKSTEMYYMFPAKISSMVLGRFLYLISYMFLIFTICGINI
                     LYLSLQNKISNIEMVVILLSAIISGILCFIQYPIYYKFGSEKAVTFIYFLPAIGVLALP
                     NFLLEKNIYLGENILQNIDFNNIIILIMFGLVILIFIGYISYLSSFKICKKREI"
     PFAM_domain     1550..2155
                     /aSDomain="ABC2_membrane_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13346.8"
                     /description="ABC-2 family transporter protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_790_0088"
                     /evalue="1.10E-14"
                     /label="ctg1_790"
                     /locus_tag="ctg1_790"
                     /protein_end="212"
                     /protein_start="10"
                     /score="54.6"
                     /tool="antismash"
                     /translation="DLRITKESTKFQILIIALFYIIFMFFKHAYVFGMSYLFFLLIIFS
                     RIPFSLQGNEKSTEMYYMFPAKISSMVLGRFLYLISYMFLIFTICGINILYLSLQNKIS
                     NIEMVVILLSAIISGILCFIQYPIYYKFGSEKAVTFIYFLPAIGVLALPNFLLEKNIYL
                     GENILQNIDFNNIIILIMFGLVILIFIGYISYLSSFKIC"
     CDS             2346..3350
                     /locus_tag="ctg1_791"
                     /transl_table=11
                     /translation="MKIKKTLAIIMAATLSVAAMTGCSEATTNYAKELANTSSWEATTS
                     EATGTVSVDAKGEKNDVTFTATGYCSGENGYSEVKFNNTQGKIKIPDIKCYIEDGIAYI
                     NKSYYEANYTMNGQAVPEGLANIKEDYIGIDLGYDNDLMKTLTSKPDSIIELSKMIFGD
                     NNDLDLPYSQNGREYTLNLDTDATVDLGVKAIKAASNNIEKINSTFNLKLTDEDMNNMK
                     TAVNGDEFNSGISDIKAQFAGSNIYSKKIFSDNDYTADTNINIKVKDLMNMSISLNQKA
                     SKSEVKSIDFPTSKIKVTQAEFNKLVSKGNEKTNVQATAQEATSGLATAYNGK"
     CDS             3582..4355
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 55; E-value:
                     1.1e-16)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_792"
                     /transl_table=11
                     /translation="MGRIKTAVILAAGMGSRLQDITQNKVPKGLIKVNGKTLVERSIEK
                     LRSLGIDKIYIVTGHLSESYDELAKKNKYIKTIKNRKYKATGSMTSLSILEHELKEDFL
                     LLESDLIYEVYGLIKVINFEQDDCVLLSGRTNSGDECYVEIRDDNLYKISKHKEEIENV
                     YGELVGISKISIELYKEMLKQYKNFNIETMEYGQRTKKYDYENAMFDAAKNRKIGYLKI
                     ENLIWGEIDDKNHLNRIEKTILPRLEKVNKVRSGL"
     PFAM_domain     3600..3929
                     /aSDomain="NTP_transferase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00483.25"
                     /description="Nucleotidyl transferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_792_0089"
                     /evalue="4.40E-11"
                     /label="ctg1_792"
                     /locus_tag="ctg1_792"
                     /protein_end="116"
                     /protein_start="6"
                     /score="42.9"
                     /tool="antismash"
                     /translation="AVILAAGMGSRLQDITQNKVPKGLIKVNGKTLVERSIEKLRSLGI
                     DKIYIVTGHLSESYDELAKKNKYIKTIKNRKYKATGSMTSLSILEHELKEDFLLLESDL
                     IYEVYG"
     CDS             4357..5655
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 220.1;
                     E-value: 6.2e-67)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_793"
                     /transl_table=11
                     /translation="MKKVYVAMSADIIHQGHLNVLNEAKKLGDVIVGLHTDDVIRGYWR
                     NPIMKYDERKEVIENIKGVVQVVLQDTLDQVPNLLDIKPDYVVHGDDWIEGSQKVFRDK
                     VINAIKEWGGKLVEVTYTQGVSISKLDEQLAEIGITPQKRMKSLKELIYSKKPVRILEA
                     HNGLTGLIVEKTKVEKNGKIKEFDGMWISSLCDSTAKGKPDIELVDLTSRLNTINDILE
                     VTTKPIIVDGDTGGQIEHFVYTVKTLERLGVSAIIIEDKTGLKKNSLFGTEVKQTQDSM
                     EHFSEKIKAGREARVTSDFMIISRIESLILKAGMDDAINRAKAYIEAGTDGIMIHSKEK
                     DGKEIVEFCKRYNEIENKVPLVVVPTSYNFMKEDELVELGINVIIYANHLIRSAYPAMV
                     NTAKSILENERSKEASSNCMPIKEILTLIPGGM"
     aSDomain        4366..4551
                     /aSDomain="TIGR00125"
                     /aSTool="tigrfam"
                     /description="cyt_tran_rel: cytidyltransferase-like domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_793_0030"
                     /evalue="2.50E-13"
                     /identifier="TIGR00125"
                     /label="ctg1_793"
                     /locus_tag="ctg1_793"
                     /protein_end="65"
                     /protein_start="3"
                     /score="48.0"
                     /tool="antismash"
                     /translation="VYVAMSADIIHQGHLNVLNEAKKLGDVIVGLHTDDVIRGYWRNPI
                     MKYDERKEVIENIKGVV"
     PFAM_domain     4384..4650
                     /aSDomain="CTP_transf_like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01467.28"
                     /description="Cytidylyltransferase-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_793_0090"
                     /evalue="1.90E-12"
                     /label="ctg1_793"
                     /locus_tag="ctg1_793"
                     /protein_end="98"
                     /protein_start="9"
                     /score="47.7"
                     /tool="antismash"
                     /translation="ADIIHQGHLNVLNEAKKLGDVIVGLHTDDVIRGYWRNPIMKYDER
                     KEVIENIKGVVQVVLQDTLDQVPNLLDIKPDYVVHGDDWIEGSQ"
     aSDomain        4798..5643
                     /aSDomain="TIGR02320"
                     /aSTool="tigrfam"
                     /description="PEP_mutase: phosphoenolpyruvate mutase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_793_0029"
                     /evalue="6.70E-125"
                     /identifier="TIGR02320"
                     /label="ctg1_793"
                     /locus_tag="ctg1_793"
                     /protein_end="429"
                     /protein_start="147"
                     /score="413.7"
                     /tool="antismash"
                     /translation="LKELIYSKKPVRILEAHNGLTGLIVEKTKVEKNGKIKEFDGMWIS
                     SLCDSTAKGKPDIELVDLTSRLNTINDILEVTTKPIIVDGDTGGQIEHFVYTVKTLERL
                     GVSAIIIEDKTGLKKNSLFGTEVKQTQDSMEHFSEKIKAGREARVTSDFMIISRIESLI
                     LKAGMDDAINRAKAYIEAGTDGIMIHSKEKDGKEIVEFCKRYNEIENKVPLVVVPTSYN
                     FMKEDELVELGINVIIYANHLIRSAYPAMVNTAKSILENERSKEASSNCMPIKEILTLI
                     P"
     PFAM_domain     4801..5574
                     /aSDomain="PEP_mutase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13714.8"
                     /description="Phosphoenolpyruvate phosphomutase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_793_0091"
                     /evalue="1.90E-64"
                     /label="ctg1_793"
                     /locus_tag="ctg1_793"
                     /protein_end="406"
                     /protein_start="148"
                     /score="217.6"
                     /tool="antismash"
                     /translation="KELIYSKKPVRILEAHNGLTGLIVEKTKVEKNGKIKEFDGMWISS
                     LCDSTAKGKPDIELVDLTSRLNTINDILEVTTKPIIVDGDTGGQIEHFVYTVKTLERLG
                     VSAIIIEDKTGLKKNSLFGTEVKQTQDSMEHFSEKIKAGREARVTSDFMIISRIESLIL
                     KAGMDDAINRAKAYIEAGTDGIMIHSKEKDGKEIVEFCKRYNEIENKVPLVVVPTSYNF
                     MKEDELVELGINVIIYANHLIRSAYPAMVNTAKSIL"
     CDS             5775..6908
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 54.5;
                     E-value: 1.5e-16)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_794"
                     /transl_table=11
                     /translation="MVDVKEFYNELLNNEIDFFTGVPDSLLKSFCGYIKDNVSNDKHIM
                     AANEGNAIGLASGYHLSTGKIGLVYMQNSGIGNAINPLASLCDKLVYSIPMLLLIGWRG
                     EPGKKDEPQHNKQGLITTKILDVMEIPYEIIDENINCDDMKLKVRTACEYMKKNNEPYA
                     LIIKKGAFGEYNLKDNSIVNFDLTREEAIEVLLSCMNENSTIVSTTGMTSRELFELREK
                     RQENHNKDFLTVGSMGHASQIALGIALNNKENDVYCIDGDGAMIMHLGGLAIIGNQEVK
                     NFKHILINNGAHDSVGGQETVGLKIDIVSIAKACGYKECYSCSSKNEIMMYSEKIKNSE
                     GSVLLEIKVKKGARKDLGRPTKTPIENKIAFMNFLQD"
     PFAM_domain     5799..6281
                     /aSDomain="TPP_enzyme_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02776.20"
                     /description="Thiamine pyrophosphate enzyme, N-terminal TPP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_794_0092"
                     /evalue="7.70E-15"
                     /label="ctg1_794"
                     /locus_tag="ctg1_794"
                     /protein_end="169"
                     /protein_start="8"
                     /score="55.0"
                     /tool="antismash"
                     /translation="NELLNNEIDFFTGVPDSLLKSFCGYIKDNVSNDKHIMAANEGNAI
                     GLASGYHLSTGKIGLVYMQNSGIGNAINPLASLCDKLVYSIPMLLLIGWRGEPGKKDEP
                     QHNKQGLITTKILDVMEIPYEIIDENINCDDMKLKVRTACEYMKKNNEPYALIIKKG"
     aSDomain        5820..6899
                     /aSDomain="TIGR03297"
                     /aSTool="tigrfam"
                     /description="Ppyr-DeCO2ase: phosphonopyruvate
                     decarboxylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_794_0031"
                     /evalue="4.10E-153"
                     /identifier="TIGR03297"
                     /label="ctg1_794"
                     /locus_tag="ctg1_794"
                     /protein_end="375"
                     /protein_start="15"
                     /score="507.6"
                     /tool="antismash"
                     /translation="IDFFTGVPDSLLKSFCGYIKDNVSNDKHIMAANEGNAIGLASGYH
                     LSTGKIGLVYMQNSGIGNAINPLASLCDKLVYSIPMLLLIGWRGEPGKKDEPQHNKQGL
                     ITTKILDVMEIPYEIIDENINCDDMKLKVRTACEYMKKNNEPYALIIKKGAFGEYNLKD
                     NSIVNFDLTREEAIEVLLSCMNENSTIVSTTGMTSRELFELREKRQENHNKDFLTVGSM
                     GHASQIALGIALNNKENDVYCIDGDGAMIMHLGGLAIIGNQEVKNFKHILINNGAHDSV
                     GGQETVGLKIDIVSIAKACGYKECYSCSSKNEIMMYSEKIKNSEGSVLLEIKVKKGARK
                     DLGRPTKTPIENKIAFMNFL"
     PFAM_domain     6450..6815
                     /aSDomain="TPP_enzyme_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02775.23"
                     /description="Thiamine pyrophosphate enzyme, C-terminal TPP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_794_0093"
                     /evalue="9.30E-16"
                     /label="ctg1_794"
                     /locus_tag="ctg1_794"
                     /protein_end="347"
                     /protein_start="225"
                     /score="58.1"
                     /tool="antismash"
                     /translation="NHNKDFLTVGSMGHASQIALGIALNNKENDVYCIDGDGAMIMHLG
                     GLAIIGNQEVKNFKHILINNGAHDSVGGQETVGLKIDIVSIAKACGYKECYSCSSKNEI
                     MMYSEKIKNSEGSVLLEI"
     CDS             6950..8071
                     /NRPS_PKS="Domain: Aminotran_5 (58-344). E-value: 4e-27.
                     Score: 86.9. Matches aSDomain:
                     nrpspksdomains_ctg1_795_Aminotran_5.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 70.2; E-value:
                     2.7e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_795"
                     /transl_table=11
                     /translation="MDIKRNILLNPGPATTSDSVKFAQVVPDICPRENDFGTVMEFISL
                     ELTNLVASSGKCTTVLFGGSGTAAVESILSSVVDNGAILIINNGAYGKRMCEIAEIYKL
                     NYIEFKSSPIDGIDLNELENKIRSYNINEKQYGITHVAVIHHETTTGILNDIKGVGKIC
                     RKYNIDMIVDAMSSFAGIPINMEEMNIKYLASSSNKCIQGMAGVSFVIANIEALEKTKS
                     IKSRNLYLNLYKQYSYFKDNYQMRFTPPVQVLYALKQAIIEAKEETIEKRYKRYKSCCK
                     ILWDGLDRLKLKRLVKDENASMLLTSIIEPNISGYSFEELHDYLYERGFTIYPGKICST
                     NTFRIANIGEIYPEEIKNFIEILREYFHEIAKH"
     aSDomain        6968..8047
                     /aSDomain="TIGR03301"
                     /aSTool="tigrfam"
                     /description="PhnW-AepZ: 2-aminoethylphosphonate
                     aminotransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_795_0032"
                     /evalue="2.80E-119"
                     /identifier="TIGR03301"
                     /label="ctg1_795"
                     /locus_tag="ctg1_795"
                     /protein_end="366"
                     /protein_start="6"
                     /score="396.6"
                     /tool="antismash"
                     /translation="ILLNPGPATTSDSVKFAQVVPDICPRENDFGTVMEFISLELTNLV
                     ASSGKCTTVLFGGSGTAAVESILSSVVDNGAILIINNGAYGKRMCEIAEIYKLNYIEFK
                     SSPIDGIDLNELENKIRSYNINEKQYGITHVAVIHHETTTGILNDIKGVGKICRKYNID
                     MIVDAMSSFAGIPINMEEMNIKYLASSSNKCIQGMAGVSFVIANIEALEKTKSIKSRNL
                     YLNLYKQYSYFKDNYQMRFTPPVQVLYALKQAIIEAKEETIEKRYKRYKSCCKILWDGL
                     DRLKLKRLVKDENASMLLTSIIEPNISGYSFEELHDYLYERGFTIYPGKICSTNTFRIA
                     NIGEIYPEEIKNFIEILREY"
     aSDomain        7124..7981
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_795_Aminotran_5.1"
                     /evalue="4.00E-27"
                     /label="ctg1_795_Aminotran_5.1"
                     /locus_tag="ctg1_795"
                     /protein_end="344"
                     /protein_start="58"
                     /score="86.9"
                     /tool="antismash"
                     /translation="TVLFGGSGTAAVESILSSVVDNGAILIINNGAYGKRMCEIAEIYK
                     LNYIEFKSSPIDGIDLNELENKIRSYNINEKQYGITHVAVIHHETTTGILNDIKGVGKI
                     CRKYNIDMIVDAMSSFAGIPINMEEMNIKYLASSSNKCIQGMAGVSFVIANIEALEKTK
                     SIKSRNLYLNLYKQYSYFKDNYQMRFTPPVQVLYALKQAIIEAKEETIEKRYKRYKSCC
                     KILWDGLDRLKLKRLVKDENASMLLTSIIEPNISGYSFEELHDYLYERGFTIYPGKICS
                     TNTFR"
     PFAM_domain     7130..7984
                     /aSDomain="Aminotran_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00266.21"
                     /description="Aminotransferase class-V"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_795_0094"
                     /evalue="2.50E-22"
                     /label="ctg1_795"
                     /locus_tag="ctg1_795"
                     /protein_end="345"
                     /protein_start="60"
                     /score="79.5"
                     /tool="antismash"
                     /translation="LFGGSGTAAVESILSSVVDNGAILIINNGAYGKRMCEIAEIYKLN
                     YIEFKSSPIDGIDLNELENKIRSYNINEKQYGITHVAVIHHETTTGILNDIKGVGKICR
                     KYNIDMIVDAMSSFAGIPINMEEMNIKYLASSSNKCIQGMAGVSFVIANIEALEKTKSI
                     KSRNLYLNLYKQYSYFKDNYQMRFTPPVQVLYALKQAIIEAKEETIEKRYKRYKSCCKI
                     LWDGLDRLKLKRLVKDENASMLLTSIIEPNISGYSFEELHDYLYERGFTIYPGKICSTN
                     TFRI"
     CDS             complement(8718..9278)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 60.5; E-value:
                     2.9e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_796"
                     /transl_table=11
                     /translation="MEDMSYWKEVWERKGRSNTKCLEELDGYEDTTANVKEIARQITIE
                     LDIKETDKILEVACGAGGLAQYIKCGEYVGVDYSSTLVKKHIKLLNNSVLHGEANDLIF
                     KDKSFDKVFCFGAFHYFPNQEYAKQAIAELKRIAKDAIFIGDLPVTSHREEHLLYDKKD
                     FQDWNITDGYYNPCRFNVSLKLR"
     PFAM_domain     complement(8862..9116)
                     /aSDomain="Methyltransf_11"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08241.14"
                     /description="Methyltransferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_796_0095"
                     /evalue="2.10E-13"
                     /label="ctg1_796"
                     /locus_tag="ctg1_796"
                     /protein_end="139"
                     /protein_start="54"
                     /score="50.8"
                     /tool="antismash"
                     /translation="LEVACGAGGLAQYIKCGEYVGVDYSSTLVKKHIKLLNNSVLHGEA
                     NDLIFKDKSFDKVFCFGAFHYFPNQEYAKQAIAELKRIAK"
     CDS             9683..10237
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_797"
                     /sec_met_domain="AgrB (E-value: 2.3e-32, bitscore: 109.8,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKELSNKIVNSVANDECSKDDIEQMDYALRTILYEFIKAFSLII
                     IFSLFGYLKQSLIITVMMCLIKPFIGGYHEETQIKCFIATLLLAAGILILSLQCSLSFV
                     SNVILIVLSIFCIWNQAPIINSKMPLTNLELIKKNRIRGVRNSIIIGIISIVLYNYSNY
                     YLLITWTILFEALLMFDKRKY"
     PFAM_domain     9698..10216
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_797_0096"
                     /evalue="6.50E-32"
                     /label="ctg1_797"
                     /locus_tag="ctg1_797"
                     /protein_end="178"
                     /protein_start="5"
                     /score="110.5"
                     /tool="antismash"
                     /translation="SNKIVNSVANDECSKDDIEQMDYALRTILYEFIKAFSLIIIFSLF
                     GYLKQSLIITVMMCLIKPFIGGYHEETQIKCFIATLLLAAGILILSLQCSLSFVSNVIL
                     IVLSIFCIWNQAPIINSKMPLTNLELIKKNRIRGVRNSIIIGIISIVLYNYSNYYLLIT
                     WTILFEALLM"
     CDS             10292..10417
                     /locus_tag="ctg1_798"
                     /transl_table=11
                     /translation="MIKKLICVFLKRVSNSMISLAPASYGGYGTEEMPEYMKKLR"
     CDS             10455..11705
                     /locus_tag="ctg1_799"
                     /transl_table=11
                     /translation="LIIIDIITSILQSIAFGYTINYCIDEEYKVSKVKLCLMILVFSII
                     GSFLFILMGYNSPISILITHILALCVVVGFYKKNIVCAITAHTMSYFIIQIYTIVFCSI
                     IYEFINEMIIIGYINYIKICTIYVPEWIILFFYFKHIDKIKEVYRLIIMEKFYINFLII
                     SFILDFITTFYMLSLGIESQLIRDIIYILFFLFFIAVIVYFWRINQKSKQIYELNKSLE
                     IKNNELRKIKHDYGAQISYLYGLCLMERFDDLKKSLKDIINNNESTPTAVEISDNENSL
                     LSLALKPAIDKGIHVIVEEKCDFKLVIMEEIELYRIISNIVNNAIRAMNGKGIIIAKTY
                     EYSGNIIIKIENNGPKIEEKHLEDIFKSGFTTKDNNDKSHGFGLHIVKNLVESYKGKIS
                     VKSTDVSTQFKIVLPIK"
     PFAM_domain     11385..11696
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_799_0097"
                     /evalue="6.60E-17"
                     /label="ctg1_799"
                     /locus_tag="ctg1_799"
                     /protein_end="414"
                     /protein_start="310"
                     /score="62.1"
                     /tool="antismash"
                     /translation="EIELYRIISNIVNNAIRAMNGKGIIIAKTYEYSGNIIIKIENNGP
                     KIEEKHLEDIFKSGFTTKDNNDKSHGFGLHIVKNLVESYKGKISVKSTDVSTQFKIVLP
                     "
     CDS             11955..12845
                     /locus_tag="ctg1_800"
                     /transl_table=11
                     /translation="MYKIINKMELTQNIYLMEIEAPRVAKAAKPGQFIIIKNDEKGERI
                     PLTIADYDKEKGTVSIVFQTVGKSTKELATYEVGECVCDFVGPLGQPSEFVHENLEELK
                     DKKIIFIAGGVGAAPVYPQVKWMHENGIAVDVILGSRNKDLLIYEEELKKVSGNLYVTT
                     DDGSYGFKGTGSDMLKELVNNQGKKYDHAVIIGPMIMMKFTSMLTKELGISTTVSLNPI
                     MVDGTGMCGACRVTVGGKVKFACVDGPEFDGHLVNYDESMRRQAMYKTEEGRATLKLEE
                     GNTHSHGGCGCRGDK"
     PFAM_domain     12282..12569
                     /aSDomain="NAD_binding_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00175.23"
                     /description="Oxidoreductase NAD-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_800_0098"
                     /evalue="1.90E-06"
                     /label="ctg1_800"
                     /locus_tag="ctg1_800"
                     /protein_end="205"
                     /protein_start="109"
                     /score="28.6"
                     /tool="antismash"
                     /translation="FIAGGVGAAPVYPQVKWMHENGIAVDVILGSRNKDLLIYEEELKK
                     VSGNLYVTTDDGSYGFKGTGSDMLKELVNNQGKKYDHAVIIGPMIMMKFTS"
     PFAM_domain     12615..12722
                     /aSDomain="DHODB_Fe-S_bind"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10418.11"
                     /description="Iron-sulfur cluster binding domain of
                     dihydroorotate dehydrogenase B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_800_0099"
                     /evalue="5.60E-12"
                     /label="ctg1_800"
                     /locus_tag="ctg1_800"
                     /protein_end="256"
                     /protein_start="220"
                     /score="45.3"
                     /tool="antismash"
                     /translation="PIMVDGTGMCGACRVTVGGKVKFACVDGPEFDGHLV"
     CDS             12845..14239
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176:alkyl hydroperoxide reductase subunit (Score:
                     42.7; E-value: 4.8e-13)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_801"
                     /transl_table=11
                     /translation="MDMNERLIRIPVREQDPKVRAKNFEEVCIGYNEEEATKEASRCLN
                     CKNPQCVKGCPVSINIPGFVEHVKNSEFENAAKEISKYSALPAVCGRVCPQEKQCEGKC
                     VLGIKGHAVSIGKLERFTADWAASHNVDLSETEAKNGIKVAVIGSGPSGLTCAGDLAKR
                     GYDVTIFEALHKAGGVLEYGIPEFRLPKEKVVKNEVENIKKLGVKIETNVIIGRTITID
                     ELFEDEGFKAVFIGSGAGLPRFMGIDGENANGVFSANEFLTRVNLMKAAVEGYDTPVRA
                     GKKVAIVGGGNVAMDAARTALRLGAESHIVYRRGESELPARAEEVHHAKEEGVIFDLLT
                     NPKEILVDENGWVKGMKCIRMELGEPDPSGRRSPIEVEGSEFIMDLDTVIMSLGTSPNP
                     LISSTTNGLEINKRRCIVAEEETGLTTKEAVYAGGDAVTGAATVILAMGAGKKAAAAID
                     EYLQSK"
     aSDomain        12893..14227
                     /aSDomain="TIGR01316"
                     /aSTool="tigrfam"
                     /description="gltA: glutamate synthase (NADPH),
                     homotetrameric"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_801_0033"
                     /evalue="2.90E-171"
                     /identifier="TIGR01316"
                     /label="ctg1_801"
                     /locus_tag="ctg1_801"
                     /protein_end="461"
                     /protein_start="16"
                     /score="568.1"
                     /tool="antismash"
                     /translation="PKVRAKNFEEVCIGYNEEEATKEASRCLNCKNPQCVKGCPVSINI
                     PGFVEHVKNSEFENAAKEISKYSALPAVCGRVCPQEKQCEGKCVLGIKGHAVSIGKLER
                     FTADWAASHNVDLSETEAKNGIKVAVIGSGPSGLTCAGDLAKRGYDVTIFEALHKAGGV
                     LEYGIPEFRLPKEKVVKNEVENIKKLGVKIETNVIIGRTITIDELFEDEGFKAVFIGSG
                     AGLPRFMGIDGENANGVFSANEFLTRVNLMKAAVEGYDTPVRAGKKVAIVGGGNVAMDA
                     ARTALRLGAESHIVYRRGESELPARAEEVHHAKEEGVIFDLLTNPKEILVDENGWVKGM
                     KCIRMELGEPDPSGRRSPIEVEGSEFIMDLDTVIMSLGTSPNPLISSTTNGLEINKRRC
                     IVAEEETGLTTKEAVYAGGDAVTGAATVILAMGAGKKAAAAIDEYL"
     PFAM_domain     12902..13234
                     /aSDomain="Fer4_20"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14691.8"
                     /description="Dihydroprymidine dehydrogenase domain II,
                     4Fe-4S cluster"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_801_0100"
                     /evalue="2.70E-43"
                     /label="ctg1_801"
                     /locus_tag="ctg1_801"
                     /protein_end="130"
                     /protein_start="19"
                     /score="146.4"
                     /tool="antismash"
                     /translation="RAKNFEEVCIGYNEEEATKEASRCLNCKNPQCVKGCPVSINIPGF
                     VEHVKNSEFENAAKEISKYSALPAVCGRVCPQEKQCEGKCVLGIKGHAVSIGKLERFTA
                     DWAASHN"
     PFAM_domain     13271..14188
                     /aSDomain="Pyr_redox_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07992.16"
                     /description="Pyridine nucleotide-disulphide
                     oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_801_0101"
                     /evalue="3.80E-30"
                     /label="ctg1_801"
                     /locus_tag="ctg1_801"
                     /protein_end="448"
                     /protein_start="142"
                     /score="105.2"
                     /tool="antismash"
                     /translation="KVAVIGSGPSGLTCAGDLAKRGYDVTIFEALHKAGGVLEYGIPEF
                     RLPKEKVVKNEVENIKKLGVKIETNVIIGRTITIDELFEDEGFKAVFIGSGAGLPRFMG
                     IDGENANGVFSANEFLTRVNLMKAAVEGYDTPVRAGKKVAIVGGGNVAMDAARTALRLG
                     AESHIVYRRGESELPARAEEVHHAKEEGVIFDLLTNPKEILVDENGWVKGMKCIRMELG
                     EPDPSGRRSPIEVEGSEFIMDLDTVIMSLGTSPNPLISSTTNGLEINKRRCIVAEEETG
                     LTTKEAVYAGGDAVTGAATVILAMG"
     CDS             14741..15466
                     /locus_tag="ctg1_802"
                     /transl_table=11
                     /translation="VNKAINLIKRLILFFVGMSIIQFGVALFLKTNIGSDTFTVFTQGL
                     ASTLDKTELRNFGLVKFIAGKPEVTPGVANMIILVVLFTAIICIERKRINIGTLICVVG
                     VGPIIDLGVKVVSLFPVDSYNYFVRALLVVFGCFIIAVGFSVLSATNVGVAPNDIVPFI
                     IQDKTKVQYRWIRITLDAGYLIIGFLLGGKVGVGTVISMVAIGPFIQFCLPYGEKFVNM
                     LTGQAKEQNEDDSEVAVQA"
     PFAM_domain     15572..15727
                     /aSDomain="HTH_Tnp_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01527.22"
                     /description="Transposase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_803_0102"
                     /evalue="1.20E-06"
                     /label="ctg1_803"
                     /locus_tag="ctg1_803"
                     /protein_end="52"
                     /protein_start="0"
                     /score="28.8"
                     /tool="antismash"
                     /translation="MGRKEKVSIEEKLRVIKSYLSGEKSAAQICSDFSIHNQSFRNWIR
                     KYNMNGE"
     CDS             15572..16252
                     /gene_functions="other (smcogs) SMCOG1164:transposase
                     IS3/IS911 family protein (Score: 32.4; E-value: 1.2e-09)"
                     /gene_kind="other"
                     /locus_tag="ctg1_803"
                     /transl_table=11
                     /translation="MGRKEKVSIEEKLRVIKSYLSGEKSAAQICSDFSIHNQSFRNWIR
                     KYNMNGENGLVVTHKNKIYSEEIKYMAIHDYLDGNGSLENICTKYEIPSIYSLQQWIKK
                     YNSHKIFKSHNKQGDRIMTNGRKTTYEERIEIVAFCISNNDDYQATADKFKVSYQQVYT
                     WVRKYKSNGYEELMDRRGKRKEPEELTESDKLSAQLKLIEAENRRLKMENDFLKKLKEV
                     ERRR"
     PFAM_domain     15965..16123
                     /aSDomain="HTH_28"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13518.8"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_803_0103"
                     /evalue="5.00E-09"
                     /label="ctg1_803"
                     /locus_tag="ctg1_803"
                     /protein_end="184"
                     /protein_start="131"
                     /score="36.2"
                     /tool="antismash"
                     /translation="ERIEIVAFCISNNDDYQATADKFKVSYQQVYTWVRKYKSNGYEEL
                     MDRRGKRK"
     CDS             16483..17139
                     /gene_functions="other (smcogs) SMCOG1026:transposase
                     (Score: 198.3; E-value: 2.4e-60)"
                     /gene_kind="other"
                     /locus_tag="ctg1_804"
                     /transl_table=11
                     /translation="MNINRLLNKQYNHKRIYRLMKSINMKSVIRKKRKSYLQSTPQITA
                     ENKLNREFYAKKPNEKWLTDVTEFKILNGQKAYLSAIFDLSDKSIISYVVGHSNNNQLV
                     FDTLDLAVIANPTAKPLFHSDRGFQYTNRTFKAKLDKINATQSMSRVSRCIDNGPMEGF
                     WGTLKCEMYYLQKFYTYEELRQAIDDYIVFYNTKRLQKNLKGLTPIEYRNQTLAS"
     PFAM_domain     16648..16944
                     /aSDomain="rve"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00665.28"
                     /description="Integrase core domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_804_0104"
                     /evalue="5.10E-15"
                     /label="ctg1_804"
                     /locus_tag="ctg1_804"
                     /protein_end="154"
                     /protein_start="55"
                     /score="55.7"
                     /tool="antismash"
                     /translation="KKPNEKWLTDVTEFKILNGQKAYLSAIFDLSDKSIISYVVGHSNN
                     NQLVFDTLDLAVIANPTAKPLFHSDRGFQYTNRTFKAKLDKINATQSMSRVSRC"
     PFAM_domain     16963..17130
                     /aSDomain="rve_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13333.8"
                     /description="Integrase core domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_804_0105"
                     /evalue="1.70E-19"
                     /label="ctg1_804"
                     /locus_tag="ctg1_804"
                     /protein_end="216"
                     /protein_start="160"
                     /score="69.8"
                     /tool="antismash"
                     /translation="EGFWGTLKCEMYYLQKFYTYEELRQAIDDYIVFYNTKRLQKNLKG
                     LTPIEYRNQTL"
     CDS             17825..18718
                     /locus_tag="ctg1_805"
                     /transl_table=11
                     /translation="MARKRSALYSIAKEIERANKRAIAEQNRINRQIERERRAFEREQK
                     ALERQNALLEKENAIKYAEILTKEAENKRYIINNLLKNIYKRKIRFNWEKYKDYSKFKE
                     VLVQEDVPLKPNEDKYKTKKSLINLLIPSRKRKEEEKLKEKLEFELQNWKNDCKRIEEG
                     NKLRKDEWLDKKSEFEKQQDSINTHQDEIKKRFENGEIDGIEFFFNEVLNSNNYPEYFN
                     LDWEIEYNNLNKMLIIEYELPKKSDIPNLKQVQYIQTRKEYKETYIKESEINKIYEEAL
                     YQLCLCVNYVYIAWII"
     CDS             18676..19419
                     /locus_tag="ctg1_806"
                     /transl_table=11
                     /translation="MLMCKLCIYSMDNLGYIEGIVFNGYLTDINKSNGIEETKCLISLQ
                     TEKSKFMKINLGNVDAKLCFKSLKGIAGAKLSDLVAVAPIININNSDKRFIESREIGNS
                     INGYNLALMHWEDFEYLIREVFEKEFSKEGAEVKITQASRDGGVDAIIFDPDPIKGGKY
                     IVQAKRYTNIVGVSAVRDLYGTVMNEGASKGILVTTSDYGRDSYEFAKNKPITLLNGAN
                     LLHILEKHGYEARIDLSEAKIYMNS"
     PFAM_domain     19012..19353
                     /aSDomain="Mrr_cat"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04471.14"
                     /description="Restriction endonuclease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_806_0106"
                     /evalue="1.60E-28"
                     /label="ctg1_806"
                     /locus_tag="ctg1_806"
                     /protein_end="226"
                     /protein_start="112"
                     /score="99.2"
                     /tool="antismash"
                     /translation="MHWEDFEYLIREVFEKEFSKEGAEVKITQASRDGGVDAIIFDPDP
                     IKGGKYIVQAKRYTNIVGVSAVRDLYGTVMNEGASKGILVTTSDYGRDSYEFAKNKPIT
                     LLNGANLLHI"
     CDS             19473..19697
                     /locus_tag="ctg1_807"
                     /transl_table=11
                     /translation="MCYLIAKKFNEEGSLVLEVEQRKRLASLSKYLTLTTLERGVQIVT
                     LNDLESFKEYSPYTLVNDEVDFISKVVNM"
     CDS             19943..20200
                     /locus_tag="ctg1_808"
                     /transl_table=11
                     /translation="LLKQINKVEGQINNIVIAITNGFVQEELKAKMDELKNRKSELEAK
                     LLEIEDKDINQIVTEADVRSLLSNFSGYVISRNVPECKNS"
ORIGIN
        1 ttgaaaatat taatttcaaa taagtctgac ttacctattt atgaacaaat taaagcacaa
       61 attaaagaac agattttaag tggtagaatt ccagaaaatg aatttttacc atcaataaga
      121 caacttgcaa aggatttggg aataagcgta attacaacga caagagctta ttcagatctt
      181 gaaagtgaag ggttcattgc tactgttaga gggaaaggca gttatgtact tcctaaagat
      241 aatgagatgg taagagaaca atatttaaaa gaaattgaag atgcttttat gattgcaatt
      301 gagaaaagta agttagctaa tatatcaaaa gatgaactta tattgatttt gaagaatttg
      361 attgaggagt gagagtaatg aacgcacttg aaataaagaa tttaaataaa gatcttaatg
      421 ggtttaatat taaaaatata aatttagaat tgcctaaggg atatatttta ggatatatag
      481 gtcagaatgg agcaggcaag actagtacaa taaaacttat tatgaatcaa cttaaacgtg
      541 atactggaga aataagagta tttggaaaac aatatgaaga tgatgaagca gaatacaagg
      601 atatgatagg atttattgga gatgagtgtt attttcctac ttgttttacg ctgaaagacg
      661 taattaatac attgaaagat ttctattctt catttgatga agttaaattt aatgaatatg
      721 ctgaaagatg ggcacttcca tataagaaaa aaattaagga tttttcaaag ggaatgaaag
      781 ctaagttatc attcgcaagt gttctatcta gggatacaaa attacttttg ttagatgaac
      841 caactagtgg acttgatcct gttgttagaa atgaaatttt agaaatatta caagaataca
      901 tttcagatgg tgagagaagt gtaatattct ctacacatat tgtgagtgac ttagaaaaaa
      961 taacagatta tctttatttt attaataatg gagaaaaagt atttcatgat acaacagaaa
     1021 atatattaga aagtcattta gtagtaaaag gtggcactga tgatttgaca aatgaattaa
     1081 aggaaaagtt attaggatat aaatcatcta atattggatt tgagggatta attaatttag
     1141 aagataaaaa atatttggat gataatttac tatttgaaaa accatctata gatgacatta
     1201 tagtatttta cattaatgct gcaaggaaaa attaataaag aatactataa gttatcgtaa
     1261 tagtgataat ataattcact aaggatttaa gaaatgaggt ttaaaacaat gaaaactatt
     1321 ctaagttatt taaaattaga tttaaggata agcaaaagaa gtttattgtg tgtagcacca
     1381 gcattaattt tttcggcata tatgtttttt gaaaagaacg tttatatatt aggttgtagc
     1441 attataactt taattatcat gggatatata tcttatttga tatcgtgtag aatttgcagg
     1501 agaaaggaag tttgataata tgaaagattc cataaattac ttgaaatttg atttaagaat
     1561 tactaaagaa agtactaagt ttcagatatt aataattgct ctattttaca ttatatttat
     1621 gttttttaaa catgcctatg tttttggaat gtcatattta ttttttttat tgataatttt
     1681 ttcaagaatc ccatttagtt tgcaagggaa tgaaaaaagt acggaaatgt attatatgtt
     1741 cccagctaaa atttcaagta tggtgttagg tagattttta tatttaatat catatatgtt
     1801 tctaatattc actatatgtg ggattaacat attataccta agtttacaaa ataaaattag
     1861 taatattgag atggtggtaa ttttattgtc agcaattata agtggcatat tatgttttat
     1921 tcagtatcct atatattata aatttggatc agaaaaagca gtaacattta tatatttttt
     1981 accagcaata ggtgttttgg cattaccaaa ctttttatta gaaaaaaata tatatttagg
     2041 tgagaatata cttcaaaata tagattttaa taatattatt attttaataa tgttcggttt
     2101 agtgatttta atttttatag gatacatttc ttatttaagt tcatttaaaa tctgtaaaaa
     2161 aagagaaata taagatattt gtatatctct aaatttgtca taaaaaatca aaaataaatt
     2221 aagattaaat taatgtttaa attaacattt atttataata tatatgtata atgtaaatat
     2281 aattaaatac atgttaatta tggttgaaat gtacaaatta aacatttgaa atgggggaat
     2341 agaaaatgaa aattaaaaaa acattagcaa ttattatggc tgcaacttta agtgtagcag
     2401 caatgactgg ttgtagcgag gcgacaacta attatgcaaa ggaacttgct aatacatcta
     2461 gctgggaagc aacaacttct gaagcaacag gaacagttag tgttgatgca aaaggagaaa
     2521 agaatgacgt tacatttaca gctacaggat attgttcagg tgagaacgga tattcagaag
     2581 ttaaatttaa taatacacaa gggaaaatta aaattccaga tattaaatgc tatatagaag
     2641 atggaattgc ctacattaat aagagctatt atgaagcaaa ttatacaatg aatggtcaag
     2701 ctgttccgga aggattagca aatataaagg aagattatat tggaatagat ttaggatatg
     2761 ataatgatct aatgaagact ttaactagta aaccagattc aataattgaa ttaagcaaaa
     2821 tgatatttgg agataataat gatcttgatt taccatattc tcaaaatgga agagaatata
     2881 ctttaaatct tgatacagat gcaacagtag atttaggcgt taaagcaatt aaagcagcat
     2941 caaataatat agaaaaaatt aatagtacat ttaatttaaa attaactgat gaagatatga
     3001 ataatatgaa aacagcagtt aatggtgatg aatttaattc tggtataagt gatattaaag
     3061 cacaatttgc tggttcaaat atttattcaa aaaaaatatt tagtgacaat gattatactg
     3121 cagatacaaa tataaatata aaagttaaag atttaatgaa tatgtcaatt tcattaaatc
     3181 aaaaagcttc taagagtgaa gtgaaatcaa tagattttcc aactagtaaa ataaaagtta
     3241 ctcaagcaga atttaataaa ttagtttcta aaggaaatga aaagacaaat gttcaggcta
     3301 cagcacaaga agcaacatca ggtttagcta cagcttataa cggaaaatag aatataccta
     3361 ataaatagat actatattta actgagtcaa gatgatatac aagtcatctt ggctcagttt
     3421 ttttattttc caatgaacat attgtattga acaatgaaag gtgttagtat aatgttgttc
     3481 aaaaaatgaa cttgtggtga acgggaaaat aataactata ttttgggaca atagaataaa
     3541 ataatgtaat gtgaagtttc aataatgggg gatgagatca aatgggaaga ataaaaacag
     3601 cagttatatt agctgcagga atggggtcta gattacagga tataactcaa aataaagttc
     3661 caaaaggtct tataaaagta aatggaaaga ccttggtaga aagatcaatt gaaaagctta
     3721 ggagtttagg aatagacaaa atttatattg ttacaggtca tttaagtgaa tcttatgatg
     3781 aattagcaaa aaaaaataaa tatattaaaa caataaaaaa tagaaaatat aaggcaacag
     3841 ggagtatgac ttctttatca atattggaac atgaattaaa ggaagatttc ttactgcttg
     3901 aaagtgattt aatatatgaa gtttatggac tgataaaagt tattaatttc gaacaagatg
     3961 attgtgtttt gttaagcgga aggacaaatt ctggagatga atgctatgtg gaaattagag
     4021 atgataattt atataagata tctaagcata aggaagaaat agaaaatgtt tatggagaat
     4081 tagttggtat ttcaaaaatt tcaatagaat tatataagga aatgttaaaa caatataaaa
     4141 attttaatat tgaaacaatg gagtatggtc aaaggacaaa aaagtatgat tatgaaaatg
     4201 ccatgtttga tgcggcaaaa aatagaaaaa taggatactt aaaaattgaa aatttaatat
     4261 ggggagaaat tgatgataaa aatcatctta atagaataga aaaaacaata cttcctagat
     4321 tagagaaagt taataaagtt aggagtggtt tataatatga aaaaagttta tgtagctatg
     4381 agcgcagata taattcatca aggacattta aatgtattaa atgaagctaa aaaattagga
     4441 gatgtaatag tagggttaca tacagatgat gtaattagag gctattggag aaatccaata
     4501 atgaagtatg acgaaagaaa agaagtgatt gaaaatatta agggagttgt acaagtagta
     4561 cttcaagata ctttagacca agttccaaat ttgttagata taaaacctga ttatgttgtt
     4621 cacggtgatg attggataga aggatctcaa aaggtgttta gagataaagt tataaatgca
     4681 ataaaagaat ggggaggaaa acttgttgaa gttacttata ctcaaggtgt atctatttca
     4741 aaattagatg aacaattagc ggaaatcgga ataactcctc aaaagagaat gaaaagttta
     4801 aaggaattaa tttattctaa aaagccagta aggatacttg aagctcataa tggtttaaca
     4861 ggattgattg ttgaaaaaac taaagttgaa aagaatggta agattaaaga atttgatgga
     4921 atgtggataa gttccttatg tgattcaacg gctaaaggta agccagatat agaattggta
     4981 gatttaacat caaggttaaa cacaattaat gatattttag aagttacaac aaagccaata
     5041 attgttgatg gtgatacagg tggacaaatt gagcattttg tttatacagt taaaactcta
     5101 gaaagattag gtgtatcagc aataattatt gaagataaga caggccttaa gaaaaattct
     5161 ttatttggaa ctgaagttaa acaaacacaa gatagtatgg aacatttctc ggaaaaaata
     5221 aaagcaggaa gagaagctag agtaactagc gattttatga taatttcaag aattgaaagt
     5281 ttaatattaa aagcgggaat ggatgatgca ataaataggg caaaagctta tattgaagct
     5341 ggtactgatg gaattatgat tcatagtaaa gagaaagacg gaaaagagat agttgaattt
     5401 tgtaaaagat ataatgaaat tgaaaataag gtgccattag tggtagttcc aacttcttat
     5461 aattttatga aggaagatga attagttgaa ttgggcataa atgtgattat ttacgcaaat
     5521 catctcatta gaagtgcata cccagcaatg gtgaatactg caaagagtat attagaaaat
     5581 gaaagatcta aggaagcctc atctaactgt atgccaataa aggaaatact tacattgatt
     5641 cctggtggaa tgtaataaga gaatgaatga tgaagaatgg atagggaatt tctaaaagat
     5701 taaaaaatta tgagaaattt ttatcttaat ctttatcatt cattattaat caattgaaat
     5761 tggagttgat ttaaatggtt gatgttaaag agttttataa tgagttatta aataatgaaa
     5821 tagatttttt tacaggagtt cctgattcat tgttaaaatc tttttgtggt tatataaaag
     5881 ataatgtaag taatgataag catataatgg ctgcaaatga gggcaatgcc ataggacttg
     5941 caagtggata tcatttaagc actggaaaga taggacttgt ctatatgcaa aattcaggaa
     6001 taggaaatgc tataaatcca cttgcatctc tttgtgataa attagtttat agtataccaa
     6061 tgcttttact tattggctgg agaggtgaac caggtaaaaa agatgaaccg cagcataaca
     6121 agcaaggatt gattacaact aaaattttag atgttatgga aataccatat gaaattatag
     6181 atgaaaatat taattgtgat gatatgaaac taaaagtgag aacagcttgc gaatatatga
     6241 agaaaaataa tgagccgtat gctttaatta taaaaaaagg agcctttggt gaatataatc
     6301 ttaaggataa ttctattgtg aattttgatt taacaagaga agaagctata gaagttttac
     6361 tatcgtgtat gaatgaaaat tcaacaatag tatcaactac aggaatgaca tcaagggaat
     6421 tatttgaact tagagaaaaa cgtcaagaaa atcataataa agatttttta actgtaggat
     6481 ctatgggaca tgcttcgcag atagctttag gaattgcatt aaataataag gaaaatgatg
     6541 tttattgcat tgacggagat ggcgcgatga ttatgcatct tggagggtta gctataatag
     6601 gaaatcaaga agttaaaaat tttaagcaca tattaataaa taatggagct catgattcgg
     6661 ttggaggaca agaaactgtt ggattaaaaa tagatatagt aagtattgca aaagcttgtg
     6721 gatataagga atgttattca tgttcatcaa agaatgaaat tatgatgtat tcagagaaaa
     6781 taaaaaattc tgaaggatca gtattattgg aaataaaagt taaaaagggt gctagaaaag
     6841 atttagggag acctactaaa acaccaattg agaataaaat tgcttttatg aattttttac
     6901 aggattgata taaagctttt aatttgaaat taagatagga gaaataaaaa tggatattaa
     6961 gagaaatata ttgttaaatc caggacctgc aacaacttct gatagcgtaa aatttgcaca
     7021 agttgttcca gatatttgcc caagagaaaa tgattttgga actgtaatgg aatttatatc
     7081 attagaactt actaatttag tagcttcaag tggtaaatgc acaactgtat tatttggtgg
     7141 gtcaggaaca gcagctgttg aatctatttt aagttcagta gttgataatg gggctatttt
     7201 gataataaat aatggtgctt atggaaagcg aatgtgtgag atagcagaaa tttataaact
     7261 aaactatata gaatttaaaa gttcacctat tgatggaata gatttaaatg agttagaaaa
     7321 taaaataaga agttataata taaatgaaaa gcaatatggt ataactcatg ttgcagtcat
     7381 acatcatgaa acaactacag gaatactaaa tgatataaaa ggtgtaggta aaatttgcag
     7441 aaaatataat atagatatga tagttgatgc aatgagttct tttgcaggaa tacctattaa
     7501 tatggaagaa atgaatataa aatatttagc ttcaagttct aataaatgca tacagggcat
     7561 ggcaggagta agttttgtaa ttgccaatat agaagcttta gaaaaaacta aaagtattaa
     7621 atcaagaaat ctgtatttaa atttatacaa acaatattca tattttaaag ataattatca
     7681 aatgcgattt acacctccag ttcaagtttt atatgcatta aaacaagcta taatagaagc
     7741 taaggaagag actatagaaa agagatacaa aagatataag tcttgctgca aaattctttg
     7801 ggatggttta gatagattaa agttaaagag attggtaaaa gatgagaatg catctatgtt
     7861 attaacatca attattgaac ctaatatatc aggatatagt tttgaagaac ttcatgatta
     7921 tttatatgaa agaggtttca ctatttatcc aggaaaaata tgttcaacaa acacttttag
     7981 aatagccaat ataggagaaa tatatccaga agaaataaaa aatttcatag aaatattacg
     8041 agaatatttc catgaaattg caaaacatta aagtttggca atgctaaccg aaattagcca
     8101 catatttgtt ccataggact aagaaaattt cgctgggaac atctaaatgc caggttgtac
     8161 ctacttcagt ttgctccaaa tataaaattt agacaaacta aaatggaaca accagacatt
     8221 aagatgttta agcagcttat tttcaaggcc tatttcacaa atatgtggct aatttctctg
     8281 tttgtgctaa actactttag attagtaata acaatgaaca ttaatataat aaaagtaagg
     8341 ttgatatgtt aaaaaagtta atttgttaac tagaaataaa agctacatat ttctagttca
     8401 tatatctatt aagatatgag gtagatttag tttaagttta aatatttata cgaaaaatac
     8461 ttaaagttat cacaaaacaa agaaatgtta ccaatatatg tgcagcaggc attggaaaat
     8521 gaattgttgg agttacttaa tgagaggttg ttcacctatt gattgttgaa agcttgcctt
     8581 tgtagcaatc tgtaggcgat gcaacctctt atttagtaac tctcaatgaa attttcctag
     8641 tcctgcgaaa catatatttg taatatttcg gttagtcatc acaaaacttc aatgttttgt
     8701 gatacattaa atactggtta acgcaatttt agcgaaacgt taaatctaca tggattgtag
     8761 taaccatcag ttatattcca gtcttggaag tcttttttat catataataa gtgctcttct
     8821 ctatgtgaag tgacaggtaa atcaccaata aagattgcat cttttgctat tctctttaat
     8881 tcagcaattg cttgttttgc atattcttga tttggaaagt agtgaaatgc accaaagcag
     8941 aatactttat cgaaactttt atctttaaaa attaaatcat ttgcttctcc atgtaaaact
     9001 gagttattaa gcaatttaat atgttttttt acaagagtac tagagtaatc cacgccaaca
     9061 tactcaccac attttatata ttgagctagt ccaccagcac cgcaagcaac ttctaatatc
     9121 ttatcagttt ccttaatatc caattcaata gtaatttgtc ttgcaatttc ttttacatta
     9181 gcagttgtat cttcgtatcc atctaattct tctaaacact tagtattact tctacctttt
     9241 ctttcccaaa cttctttcca atatgacata tcttccataa ttctctcctc ctgaatttaa
     9301 ataataatgt aaatatcaaa ttaatgatta taataatcat taattttgaa gaaaatttat
     9361 ttaataataa attaggttca tttattgaac aacattatat tatcatggtt caatgttcac
     9421 tacaataagt tcatcaaata aactaaaagt attgagtatt tttcatttaa gttaaaaaat
     9481 taaattataa atatagcatt acgtaaggaa cattaaaaaa ataccaagtc catgtgatta
     9541 ataaaatcta acaaataatt tttcaagtta tgtcattaaa aggctataaa gaggcataaa
     9601 aagattataa atatgttgaa aattaacaaa aaatggttta taatgttatt attatcaaat
     9661 aaataacaaa agagagatta aaatgataaa ggaactttct aacaaaatag taaatagtgt
     9721 agcaaatgat gagtgtagta aagatgatat tgaacagatg gactatgctt taagaactat
     9781 tttatatgaa tttataaaag cgttttcatt aataattatt ttttctttat ttggatattt
     9841 aaagcaatcc ttaattatca cagtgatgat gtgtcttatt aagcctttta taggtggata
     9901 tcatgaagaa actcaaatta agtgttttat agcaactttg ttattagcag ctggaatatt
     9961 gattctaagt ttgcaatgta gcctaagttt cgtaagtaat gttatattaa ttgttctgag
    10021 catattttgt atatggaatc aggctccaat aataaattct aaaatgccac ttacaaatct
    10081 agagttaata aagaaaaata gaattagagg tgtaagaaac tcaataataa ttggaataat
    10141 atctatagtt ttatataact atagtaatta ttatttatta ataacatgga caatattatt
    10201 tgaagcttta ctcatgtttg ataaaagaaa atattaataa atttagttgt ttattatatt
    10261 tttttataaa aattaaaagg atggtgattt tatgataaaa aaattaatat gtgtattttt
    10321 aaaaagagta tcaaactcta tgatttcatt agctccagca tcatatggag ggtatggaac
    10381 tgaagaaatg cctgaatata tgaaaaaatt aagataagcg tttcagttta ttaatttagg
    10441 aggcataatt tacattgatt ataatagata taataacttc gatattacag tcaatagcat
    10501 ttgggtatac aataaattat tgtatagatg aggaatataa agtaagcaag gttaaattat
    10561 gtttaatgat tctggtgttt tcaataatag gaagtttttt gtttatatta atgggatata
    10621 atagtccaat atcgatactt ataactcata tattagcttt atgtgtggta gttggatttt
    10681 ataaaaaaaa tattgtatgt gcaataactg cacacacaat gagttatttt attatacaaa
    10741 tctacactat tgtattttgt agcataatat atgaatttat taatgaaatg ataatcattg
    10801 gatatataaa ttatattaaa atttgtacta tttatgttcc tgaatggata atattgtttt
    10861 tttattttaa acatattgat aaaataaaag aagtttatag attaattata atggaaaagt
    10921 tttatataaa tttcttaata attagtttta tattagattt tataactact ttttatatgt
    10981 tgtctttagg tatagaaagc caactaatta gagatattat atatatacta tttttcttgt
    11041 tttttattgc tgttattgtt tatttttgga gaataaatca aaaatcaaag cagatttatg
    11101 aattgaataa atctttagaa attaaaaata atgagcttag aaaaataaaa catgattatg
    11161 gtgctcaaat ttcttattta tatggtcttt gtcttatgga aaggtttgat gatttaaaaa
    11221 aatctttaaa ggatattata aataacaatg aatcaacacc aacagctgta gaaattagtg
    11281 ataatgagaa ttcattattg tctcttgcat taaaaccagc tatagataaa ggaatacatg
    11341 taatagtaga agaaaagtgc gactttaaat tagtaatcat ggaagaaatt gaactttata
    11401 gaattatatc taatatagta aataatgcta ttagggcaat gaatggtaaa gggataataa
    11461 tagccaagac ttatgaatat tcaggaaata taataataaa aatagaaaat aacggaccta
    11521 aaatagaaga aaagcattta gaagacatat ttaaatctgg atttacgact aaagataata
    11581 atgacaaaag tcatggtttt ggattacata tagtaaaaaa tttagtagag agttacaagg
    11641 gaaaaatatc tgtaaaaagt acagatgtat ctactcaatt taaaatagtc ttgcctataa
    11701 aataattaat aatatgataa ttattttgag aaatgataaa aatatttaaa aaatttaaat
    11761 gtttttatca tttttttgaa tgataaatgg attattttta cacaaataaa acataaacaa
    11821 atatttataa tttatcaaga atagtgtaaa ctgttaagtg aaatatatct aagcacaatt
    11881 aagaaaataa tgcattagta tgcgtatcta ttgttttctt gattgtacgt aacataacaa
    11941 aggggtgcta tggaatgtat aaaataatta acaaaatgga gcttacgcaa aatatatatt
    12001 taatggaaat tgaagctcct agagtagcaa aggctgcaaa accaggacaa ttcataatta
    12061 ttaaaaatga tgaaaaagga gaaagaattc ctttaacaat tgcagattat gataaagaaa
    12121 agggaactgt atcgatagta tttcaaacag ttggaaaaag cacaaaagag ttagctacat
    12181 atgaagtagg agaatgtgta tgtgattttg ttggaccatt aggacaacct agtgaatttg
    12241 tacatgaaaa cttagaagaa ttaaaggata aaaagataat atttatagca gggggtgttg
    12301 gggcagcacc ggtatatcct caagtaaaat ggatgcatga aaatggaatt gctgtagatg
    12361 ttattttagg aagcagaaac aaagatttgt tgatatatga agaagaacta aagaaagttt
    12421 cagggaattt atatgtgaca actgatgatg gctcttatgg atttaaagga actggatcag
    12481 atatgcttaa ggaactagtt aataatcaag gcaaaaagta tgatcatgca gttatcatag
    12541 gacctatgat aatgatgaaa tttacttcta tgctaactaa ggaattagga atttcaacta
    12601 cagtaagtct taatccaata atggttgatg gtacaggaat gtgtggagct tgcagagtta
    12661 ccgttggagg aaaagttaaa tttgcttgtg ttgatggacc agaatttgat ggtcatttag
    12721 taaattacga tgaatcaatg agaagacaag ctatgtataa gactgaagaa ggaagagcta
    12781 ctttaaagtt agaagaagga aatactcata gtcatggtgg ctgtggttgc agaggtgata
    12841 aataatggat atgaatgaaa gattaattag aatacctgta agagagcaag atcctaaagt
    12901 tagagctaaa aattttgaag aagtttgtat tggatataac gaagaggaag ctacaaaaga
    12961 agcttcaaga tgtttaaatt gtaaaaatcc tcaatgcgta aagggatgcc cagtatctat
    13021 taatattcct ggatttgttg aacatgttaa aaatagcgag tttgaaaatg ctgcaaagga
    13081 aatttctaag tatagtgcac taccagcagt atgtggaaga gtatgtccac aagaaaagca
    13141 atgtgaagga aagtgcgtac taggaataaa gggccatgct gtatctattg gtaaacttga
    13201 aagatttaca gcagattggg cagcgtcaca taatgttgat ttaagtgaaa cagaagctaa
    13261 aaatggaatt aaggtggctg ttataggaag tggtccatca ggattaactt gtgctggaga
    13321 tttggctaaa agaggatatg atgttactat atttgaagca cttcacaagg ctggcggagt
    13381 tttagaatat ggtattccag aatttagact tccaaaagaa aaagtcgtta aaaatgaagt
    13441 cgaaaacatt aaaaagttag gtgttaaaat agaaactaat gttatcatag gaagaacaat
    13501 aactatagat gaattgtttg aagatgaagg atttaaagca gtatttatag gatctggtgc
    13561 aggacttcca agatttatgg ggatagatgg agaaaatgca aacggagtat tctcagcaaa
    13621 tgaattttta actagagtta acttaatgaa agctgcagta gaaggatatg atacaccagt
    13681 tagagctggt aaaaaagttg caatagttgg tggtggaaat gttgctatgg atgcagcaag
    13741 aacagcatta agactaggtg cagagagtca tattgtttat agaagaggag aatctgaact
    13801 tccggcaaga gcagaagaag tacatcatgc taaagaagaa ggtgtaatct ttgatttatt
    13861 aacaaatcca aaagaaattt tagtggatga aaacggatgg gttaaaggaa tgaagtgcat
    13921 aagaatggaa cttggtgaac cagatccatc tggaagaaga agtccaattg aagttgaagg
    13981 gtctgaattt attatggatt tagatactgt aataatgtct cttggaacat caccaaatcc
    14041 attaatttca tcaacaacta atggattaga aattaataag agaagatgta ttgtggcaga
    14101 agaagaaaca ggattaacta caaaagaagc agtttatgct ggtggagatg cagtaacagg
    14161 agcagcaaca gtaattttag ctatgggtgc tggtaaaaaa gctgcagcag ctattgatga
    14221 atatttacaa agtaagtaga atatcatgaa tttctaaatt gatactttat aaaacaaaaa
    14281 aatagatatt aaggagcctt aaaattaagc ttttaaggct cttatgcata tgaaagaaaa
    14341 taacaagttc aaaatgtcat gattaaaaat aatcttggca gatggaattg ttattttttt
    14401 gaatgtgcct tattgcatac atggttaatt agaagtataa taatcaaatg aaatgttttc
    14461 tatactatca tatcaataat tcaaatcaac agtgctttct cagttattat aacaatttac
    14521 caataagcta tgaatgaatg tgaacgaatt tgattttttt tgaatttttt ctttgacaaa
    14581 tttaaatttg tattatagaa tatactctag acagtaaata aagataatta tctcatagtc
    14641 ttatgtacaa acatttacat caaggggcga agcagatata gcgcgataac acgagttata
    14701 tattagaagt aataaatttt aaagagaagg aagaatgaaa gtgaacaaag caattaacct
    14761 aattaaaaga ctaattttat ttttcgttgg aatgagtata attcagttcg gtgtagcact
    14821 atttttaaag actaatattg gttctgatac ttttacagtt tttacacaag gattagcgtc
    14881 tacattagac aaaactgaat taagaaattt tggactagtt aaatttatag caggaaaacc
    14941 agaagtaaca ccaggcgtag ctaacatgat aattttagtt gtattattta cagcaataat
    15001 ttgcattgaa agaaaacgta taaacatagg aacattaatt tgtgttgtag gggttggacc
    15061 tattattgac cttggtgtaa aggttgtatc gttattccca gtggattctt ataattattt
    15121 tgtaagagca ttattagttg tatttggatg ttttataatt gcagtaggat tttcagtttt
    15181 atcagctact aatgtaggtg ttgcaccaaa tgatattgtt ccatttataa tacaagataa
    15241 aactaaagtt caatatcgtt ggattagaat aacactagat gcaggatatt taattatagg
    15301 atttttatta ggtggaaaag ttggagttgg tacggtaata tcaatggtag caataggacc
    15361 atttatacaa ttctgtcttc catacggaga aaaattcgta aatatgctaa caggacaagc
    15421 taaagaacaa aacgaagatg atagcgaagt agctgttcaa gcttaaaata tatttaatgt
    15481 ataatcaaaa aagtagttgc taaaatgata tgctcccttt atagtagaca gttaaaataa
    15541 taaaactgtt tctataaagg gggtgttttt tatgggcaga aaagaaaaag tttctattga
    15601 agaaaagcta agagttatta aatcttacct atcaggtgaa aaaagtgctg cacaaatatg
    15661 ttctgatttt agcatccata atcaatcatt taggaattgg attcgtaagt ataatatgaa
    15721 tggtgaaaac ggattagttg ttactcataa aaataaaatt tattcagaag aaatcaaata
    15781 tatggcaatt catgattatc ttgatggcaa cggttcattg gaaaatatat gcactaaata
    15841 tgaaattcca tcaatttata gtctccaaca atggattaag aagtataata gtcataagat
    15901 atttaaatct cacaataagc aaggggatag aattatgact aatggaagaa aaaccactta
    15961 tgaagaaaga attgagattg ttgcattctg catttcgaat aatgatgatt atcaagccac
    16021 tgctgataaa tttaaggttt cttatcaaca agtttataca tgggtaagaa aatataaatc
    16081 taatggatat gaagagttaa tggaccgtcg cggtaagcgt aaagagcctg aggagcttac
    16141 tgagtctgat aaattatcag cacaactaaa acttattgaa gcagaaaata gacgtttaaa
    16201 gatggagaat gatttcttaa aaaaattgaa ggaagtagaa agaaggcgat aagcactaga
    16261 atcatccaag aatataaata tatttctata aaagaattac atgaggaaaa tggctatcca
    16321 atagctgatt tatgcaattt agctagtatt gcacgatcat cttactacaa atggattaac
    16381 cgttcagaga ctgaattaga taaagagaat tcaataatac taaaagaaat tgttaagctt
    16441 tatgaagatg tacatggtat ctatggatac cgtcggataa caatgaatat aaatcgactt
    16501 cttaataaac agtataatca taaacgaatt tatagattaa tgaagtctat taacatgaaa
    16561 tcagttataa gaaaaaagag aaagtcttat ctacaaagta ctccacaaat aacggcagaa
    16621 aacaaattaa atagagaatt ctatgcaaag aaaccaaatg aaaaatggtt aacagatgtt
    16681 actgagttta agatacttaa tggtcaaaag gcttacctca gtgcaatatt tgatttatct
    16741 gataaaagca ttatttctta tgtggtcggt cactcaaata acaatcaact tgtttttgat
    16801 acacttgact tagcagtaat tgctaatccg actgcaaagc cactttttca tagtgatagg
    16861 ggatttcaat atactaatag aactttcaag gctaaacttg ataagattaa tgcaactcaa
    16921 agcatgtcac gtgtcagtag gtgtatcgac aacggaccaa tggaaggttt ttggggaact
    16981 ctcaaatgcg agatgtatta tttgcaaaaa ttttatactt atgaagaatt aagacaagcg
    17041 attgatgatt acatagtatt ttataataca aagaggttac agaaaaattt aaaaggtctg
    17101 actccaattg aatatcgaaa tcagacctta gcttcataat ttttttattt tttcatctgt
    17161 ctacttgaca gggggcagtt caaaatggca gctactttta tttattcaaa attatgttat
    17221 ttgacaatgc atttataatg ctatataatt tacaatacaa ggtgaacatt ctttgaaaag
    17281 tgaatatgtt attaaaccat cttaaacctg ggggcgtttt ggcttcgacg ggggcgggat
    17341 cgggtttgtt aagcgagtcg agggaagcat gtgtcctcgt taataaagta tgcattaaat
    17401 gtaaacgcag aagacaattt tgcattagca gcttagttta atagctgttc atcagcccgg
    17461 gttgcctacg gctcggatca ctggtgtcat ttaagtggga aacgaagttt agcaaagctt
    17521 tgagctaaag gggtatttat gaagctaccg gaaagtatag cctgcctaag ggcgctgctt
    17581 ttggggaatc ttaaaactta gactgcactc ggagaaagac aaattcagct gctttcggac
    17641 aggggttcga tacccctcgc ctccaccatg aaacccacga aaatctaaaa tttggatttt
    17701 cgtgggttta tttttattta tgactagtgt aatataaaaa tagattattc catattatac
    17761 aaatgaaaat ataaatttaa aaatagttat agaatataaa taatatttat gaggagtgaa
    17821 gaatatggct agaaaacgtt cagctttata tagtatagcc aaagaaatag aaagagcaaa
    17881 taaaagagct attgctgaac aaaatagaat taacaggcaa atagaaagag aaagaagagc
    17941 ttttgagaga gagcaaaaag cattagaaag acaaaatgcc cttttagaaa aagaaaatgc
    18001 aataaagtat gcagaaatat taacaaagga agcagaaaat aaaagatata ttataaataa
    18061 tttgttaaaa aatatttata aaagaaagat aaggtttaat tgggaaaagt ataaagatta
    18121 ttcgaaattt aaagaggttt tagttcaaga agacgttcct ctaaaaccta atgaagataa
    18181 atataaaaca aaaaaatcac taattaattt attgatacca tctagaaaaa gaaaagaaga
    18241 agaaaagctt aaagaaaagc tagagtttga attacaaaat tggaaaaatg attgtaagag
    18301 aatagaagaa ggaaataaat taaggaaaga tgaatggtta gataaaaaaa gtgaatttga
    18361 aaaacagcaa gattcaatta atactcatca agatgagata aaaaagagat ttgagaacgg
    18421 ggagatagat gggatagaat tcttttttaa tgaagtgcta aacagcaata attatccgga
    18481 gtatttcaat ttagactggg aaatagaata taataattta aataaaatgt taattatcga
    18541 atatgagctt cctaaaaaat cagatattcc aaacttgaaa caagtgcaat atattcaaac
    18601 aagaaaggaa tataaggaaa catatattaa agaatcagaa ataaataaaa tttatgaaga
    18661 agcattatat caattatgct tatgtgtaaa ttatgtatat atagcatgga taatttaggt
    18721 tatatagaag gtatagtatt taatggatat ttaacagata taaataaaag taatggtata
    18781 gaagaaacaa aatgtttaat atcattacaa actgaaaaat caaaatttat gaaaattaat
    18841 ttgggaaatg tagatgcaaa attatgtttt aagagtctaa aaggaattgc aggtgcaaag
    18901 ttaagtgatt tggttgcagt tgcaccaata attaatataa ataatagtga taaaagattt
    18961 attgaatcac gtgaaatagg aaattcaata aatggatata atcttgcttt aatgcattgg
    19021 gaagattttg aatatttaat tagagaagta tttgaaaaag agttttcaaa agaaggagca
    19081 gaggtaaaaa taactcaggc aagtagagat ggaggtgtag atgctataat atttgatcca
    19141 gatccaataa agggtggaaa atatatagta caggccaaaa gatatactaa tatagtagga
    19201 gtttctgctg taagagattt atatggaact gttatgaatg aaggtgcatc aaaaggaatt
    19261 ttagttacaa cgtctgatta tggtagagat tcatatgaat ttgcaaaaaa taagccaata
    19321 accttattaa atggagctaa tttattacat atattagaga aacatggata tgaggctaga
    19381 atagatttaa gtgaggctaa aatttatatg aattcatagc gttcgtatta attagaaata
    19441 tataggtgtg tcaagcatag aggttgtaga acatgtgtta tctaatagca aagaaattta
    19501 atgaagaagg cagtttagta ttagaagttg agcaacgaaa aagattagca tcattatcta
    19561 aatatttaac attaacaaca ttagaacgtg gtgttcaaat agtaacatta aatgacttag
    19621 aaagttttaa ggaatattct ccatatacat tggtaaatga tgaagttgat tttataagta
    19681 aagttgttaa tatgtaatat attgagacta aaaagagatg aaatttattg gtggatttca
    19741 aaggtcacgc ttcgcctcca ccataaaaaa cacgatcatt tgtatgtggc ttaaatagct
    19801 gcttacaggt ggtcgtgttt tttatggtta cggggtagcg ttacaatcaa acccacagaa
    19861 atctaaaaat ctataattgc agaagaaatt gataagaaca taaaaaaagc aaaataaagc
    19921 tgatagtgaa aagaaggcag tattgctaaa acaaataaat aaagttgaag gtcaaattaa
    19981 taatatagta attgctataa caaatggatt tgttcaagaa gagttgaaag ctaaaatgga
    20041 tgagcttaag aataggaaga gtgaattaga agctaagttg ttagaaattg aggataaaga
    20101 cattaatcaa atcgtaacag aagcagatgt aagaagcttg ttaagcaatt ttagtggcta
    20161 tgtaattagc aggaatgttc cagaatgcaa aaattcataa
//
