LOCUS       c00002_NZ_CYUJ..       20710 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CYUJ01000002.1 Neofamilia massiliensis strain SIT13, whole genome
            shotgun sequence.
ACCESSION   NZ_CYUJ01000002
VERSION     NZ_CYUJ01000002
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:30:30
            Original ID  :: NZ_CYUJ01000002.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 361780
            Orig. end    :: 382490
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20710
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[371780:372490]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10710
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..20710
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20710
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             607..1926
                     /locus_tag="ctg2_332"
                     /transl_table=11
                     /translation="MKTIQITAPASNSGKTITTSIIARALKNRGLDLVGFKCGPDFIDS
                     KYLAFASKKDNGNLDVHLCGTKGMKHALALNKGAYAIVEGAMGYFDGIGLGYEASAYDI
                     GRTLDLPGILVYKPQGEMFTIVPKVKGMVDYSQGRLKGIIFSATTKTMYGYLKKMLEDH
                     VDIKVLGYIEKDEDLNFGSRNLGLMLPEELEEFDNILDAQAKKSEETIDYESLIDLMAD
                     INVDQGMEEIKKTPYTIAIARDQAFCFHYGENIKLFEKYFTVKYFSPLRDKTLPEADLV
                     YIDGGYPEIYIDELAANKSMLKSVRAYIEAGGFYLGQGAGLLYLTENLDGRDLVGIFKT
                     QSQMTNRLQNFGYVNLILEEDLLLGDSGTLIPAHEFHYSKIEENLPASIRVEKASKLKT
                     WSGGYKYKNALGLYQHINFAGNESVIDHIIKKLGEENVYK"
     PFAM_domain     622..1143
                     /aSDomain="CbiA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01656.25"
                     /description="CobQ/CobB/MinD/ParA nucleotide binding
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_332_0001"
                     /evalue="9.30E-07"
                     /label="ctg2_332"
                     /locus_tag="ctg2_332"
                     /protein_end="179"
                     /protein_start="5"
                     /score="29.0"
                     /tool="antismash"
                     /translation="ITAPASNSGKTITTSIIARALKNRGLDLVGFKCGPDFIDSKYLAF
                     ASKKDNGNLDVHLCGTKGMKHALALNKGAYAIVEGAMGYFDGIGLGYEASAYDIGRTLD
                     LPGILVYKPQGEMFTIVPKVKGMVDYSQGRLKGIIFSATTKTMYGYLKKMLEDHVDIKV
                     LGYIEKDEDLN"
     aSDomain        622..1899
                     /aSDomain="TIGR00379"
                     /aSTool="tigrfam"
                     /description="cobB: cobyrinic acid a,c-diamide synthase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg2_332_0001"
                     /evalue="1.10E-78"
                     /identifier="TIGR00379"
                     /label="ctg2_332"
                     /locus_tag="ctg2_332"
                     /protein_end="431"
                     /protein_start="5"
                     /score="263.2"
                     /tool="antismash"
                     /translation="ITAPASNSGKTITTSIIARALKNRGLDLVGFKCGPDFIDSKYLAF
                     ASKKDNGNLDVHLCGTKGMKHALALNKGAYAIVEGAMGYFDGIGLGYEASAYDIGRTLD
                     LPGILVYKPQGEMFTIVPKVKGMVDYSQGRLKGIIFSATTKTMYGYLKKMLEDHVDIKV
                     LGYIEKDEDLNFGSRNLGLMLPEELEEFDNILDAQAKKSEETIDYESLIDLMADINVDQ
                     GMEEIKKTPYTIAIARDQAFCFHYGENIKLFEKYFTVKYFSPLRDKTLPEADLVYIDGG
                     YPEIYIDELAANKSMLKSVRAYIEAGGFYLGQGAGLLYLTENLDGRDLVGIFKTQSQMT
                     NRLQNFGYVNLILEEDLLLGDSGTLIPAHEFHYSKIEENLPASIRVEKASKLKTWSGGY
                     KYKNALGLYQHINFAGNESVIDHIIKK"
     PFAM_domain     1318..1869
                     /aSDomain="GATase_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07685.16"
                     /description="CobB/CobQ-like glutamine amidotransferase
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_332_0002"
                     /evalue="1.80E-21"
                     /label="ctg2_332"
                     /locus_tag="ctg2_332"
                     /protein_end="421"
                     /protein_start="237"
                     /score="76.7"
                     /tool="antismash"
                     /translation="TIAIARDQAFCFHYGENIKLFEKYFTVKYFSPLRDKTLPEADLVY
                     IDGGYPEIYIDELAANKSMLKSVRAYIEAGGFYLGQGAGLLYLTENLDGRDLVGIFKTQ
                     SQMTNRLQNFGYVNLILEEDLLLGDSGTLIPAHEFHYSKIEENLPASIRVEKASKLKTW
                     SGGYKYKNALGLYQHINFAGN"
     CDS             1913..2533
                     /locus_tag="ctg2_333"
                     /transl_table=11
                     /translation="MYINNPMEIENKSMDIIEEGLNKTNFTEEEKIVVKRTIHTTGDLD
                     YQNIVDFKEDFVNVAKNSLKNKVKIYTDTNMTKAGVNKKALEKLGLEIVCYIADEDVAK
                     KAKEEGTTRSQAAIEKAIKEGVTCFSIGNAPTALYKLLEEYDAGRAKVDFVIGVPVGFV
                     GAAESKEDLRGYKIPQVTTIGNKGGSNVAASIINALMYMLVER"
     PFAM_domain     1934..2518
                     /aSDomain="CbiC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02570.17"
                     /description="Precorrin-8X methylmutase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_333_0003"
                     /evalue="1.30E-70"
                     /label="ctg2_333"
                     /locus_tag="ctg2_333"
                     /protein_end="202"
                     /protein_start="7"
                     /score="237.2"
                     /tool="antismash"
                     /translation="EIENKSMDIIEEGLNKTNFTEEEKIVVKRTIHTTGDLDYQNIVDF
                     KEDFVNVAKNSLKNKVKIYTDTNMTKAGVNKKALEKLGLEIVCYIADEDVAKKAKEEGT
                     TRSQAAIEKAIKEGVTCFSIGNAPTALYKLLEEYDAGRAKVDFVIGVPVGFVGAAESKE
                     DLRGYKIPQVTTIGNKGGSNVAASIINALMYM"
     CDS             2530..3615
                     /locus_tag="ctg2_334"
                     /transl_table=11
                     /translation="MKKLDLYIDKDGEKLRCGYTTGSTATGATKAAAIMLLSQREISEI
                     KIKTPAGVDLDLEVESAEIGKDYAIASVKKDSGDDPDATKEVEIFSKVSLRDDGEIFIT
                     GGPGVGRITQKGIYGDIGDYAINPVPRQMMERELLDLGEDTGYNVEIFIPQGEEISKRT
                     FNKNIGIEGGISIIGTKGIVYPMSEEALLKSIYMEIESIKLKQGTEKTLMLTPGNYGEE
                     YAKKLGDDIKVVQVSNYVGRCLKYAYKAGFRDFFLLGHIGKFSKLSMGAFNTHNETVDL
                     RMEAFVYYLALKGVDLDHLKTIDKFLTAEEASKYIFENNLDFVFKDMEAGCQRRIKKYL
                     KDDQIKVQVKMYSMSRGMLSD"
     PFAM_domain     2572..3339
                     /aSDomain="CbiD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01888.19"
                     /description="CbiD"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_334_0004"
                     /evalue="5.40E-84"
                     /label="ctg2_334"
                     /locus_tag="ctg2_334"
                     /protein_end="270"
                     /protein_start="14"
                     /score="281.5"
                     /tool="antismash"
                     /translation="LRCGYTTGSTATGATKAAAIMLLSQREISEIKIKTPAGVDLDLEV
                     ESAEIGKDYAIASVKKDSGDDPDATKEVEIFSKVSLRDDGEIFITGGPGVGRITQKGIY
                     GDIGDYAINPVPRQMMERELLDLGEDTGYNVEIFIPQGEEISKRTFNKNIGIEGGISII
                     GTKGIVYPMSEEALLKSIYMEIESIKLKQGTEKTLMLTPGNYGEEYAKKLGDDIKVVQV
                     SNYVGRCLKYAYKAGFRDFFLLGHIGKFSKLSMG"
     aSDomain        2599..3606
                     /aSDomain="TIGR00312"
                     /aSTool="tigrfam"
                     /description="cbiD: cobalamin biosynthesis protein CbiD"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg2_334_0002"
                     /evalue="4.60E-69"
                     /identifier="TIGR00312"
                     /label="ctg2_334"
                     /locus_tag="ctg2_334"
                     /protein_end="359"
                     /protein_start="23"
                     /score="230.8"
                     /tool="antismash"
                     /translation="TATGATKAAAIMLLSQREISEIKIKTPAGVDLDLEVESAEIGKDY
                     AIASVKKDSGDDPDATKEVEIFSKVSLRDDGEIFITGGPGVGRITQKGIYGDIGDYAIN
                     PVPRQMMERELLDLGEDTGYNVEIFIPQGEEISKRTFNKNIGIEGGISIIGTKGIVYPM
                     SEEALLKSIYMEIESIKLKQGTEKTLMLTPGNYGEEYAKKLGDDIKVVQVSNYVGRCLK
                     YAYKAGFRDFFLLGHIGKFSKLSMGAFNTHNETVDLRMEAFVYYLALKGVDLDHLKTID
                     KFLTAEEASKYIFENNLDFVFKDMEAGCQRRIKKYLKDDQIKVQVKMYSMSRGML"
     CDS             3608..4213
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TP_methylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_335"
                     /sec_met_domain="TP_methylase (E-value: 1.6e-17, bitscore:
                     59.9, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIKLIGAGPGNINLLTLQALDEIKTADKVIAFERIAKDLHSLRPD
                     IIVIKRVDQVLDQLEKIGGDETVAIMASGDSCFFGIIDLLKRKGVEIEEVLVGISSVQY
                     FFNRLQKSYSSLETRSVHGRDFDFSTIDKDKKYSFLIDQEKNANYISKKLKDQGLSGKI
                     YCGYNLSYDDEKILTINIGDQIDEPSILGVVVVEFNVD"
     PFAM_domain     3617..4153
                     /aSDomain="TP_methylase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00590.22"
                     /description="Tetrapyrrole (Corrin/Porphyrin) Methylases"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_335_0005"
                     /evalue="6.20E-15"
                     /label="ctg2_335"
                     /locus_tag="ctg2_335"
                     /protein_end="182"
                     /protein_start="3"
                     /score="55.8"
                     /tool="antismash"
                     /translation="LIGAGPGNINLLTLQALDEIKTADKVIAFERIAKDLHSLRPDIIV
                     IKRVDQVLDQLEKIGGDETVAIMASGDSCFFGIIDLLKRKGVEIEEVLVGISSVQYFFN
                     RLQKSYSSLETRSVHGRDFDFSTIDKDKKYSFLIDQEKNANYISKKLKDQGLSGKIYCG
                     YNLSYDDEKILTINIG"
     aSDomain        3617..4168
                     /aSDomain="TIGR02467"
                     /aSTool="tigrfam"
                     /description="CbiE: precorrin-6y C5,15-methyltransferase
                     (decarboxylating), CbiE subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg2_335_0003"
                     /evalue="7.50E-40"
                     /identifier="TIGR02467"
                     /label="ctg2_335"
                     /locus_tag="ctg2_335"
                     /protein_end="187"
                     /protein_start="3"
                     /score="134.5"
                     /tool="antismash"
                     /translation="LIGAGPGNINLLTLQALDEIKTADKVIAFERIAKDLHSLRPDIIV
                     IKRVDQVLDQLEKIGGDETVAIMASGDSCFFGIIDLLKRKGVEIEEVLVGISSVQYFFN
                     RLQKSYSSLETRSVHGRDFDFSTIDKDKKYSFLIDQEKNANYISKKLKDQGLSGKIYCG
                     YNLSYDDEKILTINIGDQIDE"
     CDS             4203..4748
                     /locus_tag="ctg2_336"
                     /transl_table=11
                     /translation="MWIKDEEFIRGQVPMTKFSVRSLIIANLAVKDDDRLLDIGCGTGS
                     ISVEAACHGATVFAVDKNPEAVSLTKENAKKFDQDIEVLERNVPDGLDDIKINKCFVGG
                     STGRLEDIFSYLEKNLEAGGVLVGSFILLKNLFEFKELLKKYAYKDLEVNLVQVATEDK
                     IGLMRGENPIFIVKGVKV"
     PFAM_domain     4233..4622
                     /aSDomain="PrmA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06325.15"
                     /description="Ribosomal protein L11 methyltransferase
                     (PrmA)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_336_0006"
                     /evalue="7.40E-09"
                     /label="ctg2_336"
                     /locus_tag="ctg2_336"
                     /protein_end="140"
                     /protein_start="10"
                     /score="35.5"
                     /tool="antismash"
                     /translation="GQVPMTKFSVRSLIIANLAVKDDDRLLDIGCGTGSISVEAACHGA
                     TVFAVDKNPEAVSLTKENAKKFDQDIEVLERNVPDGLDDIKINKCFVGGSTGRLEDIFS
                     YLEKNLEAGGVLVGSFILLKNLFEFK"
     aSDomain        4242..4595
                     /aSDomain="TIGR02469"
                     /aSTool="tigrfam"
                     /description="CbiT: precorrin-6Y C5,15-methyltransferase
                     (decarboxylating), CbiT subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg2_336_0004"
                     /evalue="6.30E-30"
                     /identifier="TIGR02469"
                     /label="ctg2_336"
                     /locus_tag="ctg2_336"
                     /protein_end="131"
                     /protein_start="13"
                     /score="102.0"
                     /tool="antismash"
                     /translation="PMTKFSVRSLIIANLAVKDDDRLLDIGCGTGSISVEAACHGATVF
                     AVDKNPEAVSLTKENAKKFDQDIEVLERNVPDGLDDIKINKCFVGGSTGRLEDIFSYLE
                     KNLEAGGVLVGSFI"
     PFAM_domain     4745..5365
                     /aSDomain="TP_methylase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00590.22"
                     /description="Tetrapyrrole (Corrin/Porphyrin) Methylases"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_337_0007"
                     /evalue="6.90E-44"
                     /label="ctg2_337"
                     /locus_tag="ctg2_337"
                     /protein_end="207"
                     /protein_start="0"
                     /score="150.4"
                     /tool="antismash"
                     /translation="MIHFVGAGPGNPDLITIRGRDLLEKADILIWAGSLVSPDHLKYTK
                     ESCEIYDSKGMNLDEVIEVMLRGHEEGKEIVRLHTGDPTIYGAIREQMDRLEEAGIEYE
                     VVPGVSSFTGACAAIKREFTLPGVSQTVILTRNAGRTPVPEGEELEKLASHKASMAIFL
                     SVQDIDSVVEKLKKGYGSGDVPVAIVFKATWDDQEILYGTLDTI"
     CDS             4745..5506
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TP_methylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_337"
                     /sec_met_domain="TP_methylase (E-value: 9.7e-46, bitscore:
                     152.1, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHFVGAGPGNPDLITIRGRDLLEKADILIWAGSLVSPDHLKYTK
                     ESCEIYDSKGMNLDEVIEVMLRGHEEGKEIVRLHTGDPTIYGAIREQMDRLEEAGIEYE
                     VVPGVSSFTGACAAIKREFTLPGVSQTVILTRNAGRTPVPEGEELEKLASHKASMAIFL
                     SVQDIDSVVEKLKKGYGSGDVPVAIVFKATWDDQEILYGTLDTISDQVKKANIKKMSQI
                     LVGNFIEGDYELSKLYDKHFTHKFRKGIEEK"
     aSDomain        4748..5485
                     /aSDomain="TIGR01465"
                     /aSTool="tigrfam"
                     /description="cobM_cbiF: precorrin-4 C11-methyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg2_337_0005"
                     /evalue="5.50E-101"
                     /identifier="TIGR01465"
                     /label="ctg2_337"
                     /locus_tag="ctg2_337"
                     /protein_end="247"
                     /protein_start="1"
                     /score="334.9"
                     /tool="antismash"
                     /translation="IHFVGAGPGNPDLITIRGRDLLEKADILIWAGSLVSPDHLKYTKE
                     SCEIYDSKGMNLDEVIEVMLRGHEEGKEIVRLHTGDPTIYGAIREQMDRLEEAGIEYEV
                     VPGVSSFTGACAAIKREFTLPGVSQTVILTRNAGRTPVPEGEELEKLASHKASMAIFLS
                     VQDIDSVVEKLKKGYGSGDVPVAIVFKATWDDQEILYGTLDTISDQVKKANIKKMSQIL
                     VGNFIEGDYELSKLYDKHFTHKFR"
     CDS             5503..6492
                     /locus_tag="ctg2_338"
                     /transl_table=11
                     /translation="MIKIFSYSQAGLDLGEKIKDFLSADHYNKRITAFDVKIILKENWQ
                     AAEAFIFISSTGIAVRMIKDFIKAKDQDPAIIVIDDTGKNVISLLSGHLGGANDLTRTL
                     AEFLGANPVITTSTDNHGIEAVDSFARTNDYRLADKNKILPISKLMLEGKTIGFYSEVD
                     KVIDYNHIKVLENLDDLSGLDGLIVVSNKIERDLPIPSIYLHPKNLNLGIGCRRDTPGE
                     KIISFIKDQLNDLGLSFYSIKKIGSVEAKRDEVGIQEAADYFKVEKKIFSNDQIKTVED
                     KFDKSDFVKKTIGVYSVAEPCAYLLGGRLLTKRLKKDGITLAISLEDK"
     PFAM_domain     5620..5859
                     /aSDomain="CbiG_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11760.10"
                     /description="Cobalamin synthesis G N-terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_338_0008"
                     /evalue="1.60E-32"
                     /label="ctg2_338"
                     /locus_tag="ctg2_338"
                     /protein_end="119"
                     /protein_start="39"
                     /score="111.5"
                     /tool="antismash"
                     /translation="LKENWQAAEAFIFISSTGIAVRMIKDFIKAKDQDPAIIVIDDTGK
                     NVISLLSGHLGGANDLTRTLAEFLGANPVITTSTD"
     PFAM_domain     5875..6120
                     /aSDomain="CbiG_mid"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11761.10"
                     /description="Cobalamin biosynthesis central region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_338_0009"
                     /evalue="2.40E-05"
                     /label="ctg2_338"
                     /locus_tag="ctg2_338"
                     /protein_end="206"
                     /protein_start="124"
                     /score="24.4"
                     /tool="antismash"
                     /translation="AVDSFARTNDYRLADKNKILPISKLMLEGKTIGFYSEVDKVIDYN
                     HIKVLENLDDLSGLDGLIVVSNKIERDLPIPSIYLHP"
     PFAM_domain     6130..6474
                     /aSDomain="CbiG_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01890.18"
                     /description="Cobalamin synthesis G C-terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_338_0010"
                     /evalue="5.60E-29"
                     /label="ctg2_338"
                     /locus_tag="ctg2_338"
                     /protein_end="324"
                     /protein_start="209"
                     /score="101.1"
                     /tool="antismash"
                     /translation="NLGIGCRRDTPGEKIISFIKDQLNDLGLSFYSIKKIGSVEAKRDE
                     VGIQEAADYFKVEKKIFSNDQIKTVEDKFDKSDFVKKTIGVYSVAEPCAYLLGGRLLTK
                     RLKKDGITLAI"
     CDS             6489..7217
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TP_methylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_339"
                     /sec_met_domain="TP_methylase (E-value: 2.5e-40, bitscore:
                     134.5, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLYVIGIGPGGKERMTQEALAAIEKSDVIVAYTPYLEYVKDYI
                     KDKETFTSGMRKEVERCQKAIDFAREGKTTSILSTGDAGLYGMAGPILELLKGDEEVQV
                     EIVPGVSSVFSAAAELGAPVMHDLAIISLSDLMTPWDLIQKRIDLAAQGDFVISLYNPR
                     SKGRPDHLQTAIEIILKHKSPDTPVGVVKNSGRENKEQWVTTLKDLDYEKVDMLTILII
                     GNKASYIDGDKIITPRGYEI"
     PFAM_domain     6495..7115
                     /aSDomain="TP_methylase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00590.22"
                     /description="Tetrapyrrole (Corrin/Porphyrin) Methylases"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_339_0011"
                     /evalue="2.30E-39"
                     /label="ctg2_339"
                     /locus_tag="ctg2_339"
                     /protein_end="209"
                     /protein_start="2"
                     /score="135.6"
                     /tool="antismash"
                     /translation="KLYVIGIGPGGKERMTQEALAAIEKSDVIVAYTPYLEYVKDYIKD
                     KETFTSGMRKEVERCQKAIDFAREGKTTSILSTGDAGLYGMAGPILELLKGDEEVQVEI
                     VPGVSSVFSAAAELGAPVMHDLAIISLSDLMTPWDLIQKRIDLAAQGDFVISLYNPRSK
                     GRPDHLQTAIEIILKHKSPDTPVGVVKNSGRENKEQWVTTLKDL"
     aSDomain        6498..7211
                     /aSDomain="TIGR01466"
                     /aSTool="tigrfam"
                     /description="cobJ_cbiH: precorrin-3B
                     C17-methyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg2_339_0006"
                     /evalue="8.40E-95"
                     /identifier="TIGR01466"
                     /label="ctg2_339"
                     /locus_tag="ctg2_339"
                     /protein_end="241"
                     /protein_start="3"
                     /score="314.8"
                     /tool="antismash"
                     /translation="LYVIGIGPGGKERMTQEALAAIEKSDVIVAYTPYLEYVKDYIKDK
                     ETFTSGMRKEVERCQKAIDFAREGKTTSILSTGDAGLYGMAGPILELLKGDEEVQVEIV
                     PGVSSVFSAAAELGAPVMHDLAIISLSDLMTPWDLIQKRIDLAAQGDFVISLYNPRSKG
                     RPDHLQTAIEIILKHKSPDTPVGVVKNSGRENKEQWVTTLKDLDYEKVDMLTILIIGNK
                     ASYIDGDKIITPRGYE"
     CDS             7214..7954
                     /locus_tag="ctg2_340"
                     /transl_table=11
                     /translation="MIWIVGGTSESVALGKIFEEKNIPHLITYATKDGLELATDKAINK
                     DESVEDFIVHKDIDTIIDLTHPFAVKMTDKVKKAAEKFQISYLRYERERVSYPADAILV
                     DSYEEAYDKLKDMSGTFFFTTGSNKIADFEKVKGHKRFVYRILPTVDSITKAREAGVEI
                     RDLVAMLGPFSEEINLAMLRTFQADYLVTKDSGKAGGVEEKISAAESLGIVPIIITRDQ
                     VATKTWEDFLLEVEKFLSIKKSRT"
     PFAM_domain     7217..7900
                     /aSDomain="CbiJ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02571.16"
                     /description="Precorrin-6x reductase CbiJ/CobK"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_340_0012"
                     /evalue="5.40E-61"
                     /label="ctg2_340"
                     /locus_tag="ctg2_340"
                     /protein_end="229"
                     /protein_start="1"
                     /score="206.1"
                     /tool="antismash"
                     /translation="IWIVGGTSESVALGKIFEEKNIPHLITYATKDGLELATDKAINKD
                     ESVEDFIVHKDIDTIIDLTHPFAVKMTDKVKKAAEKFQISYLRYERERVSYPADAILVD
                     SYEEAYDKLKDMSGTFFFTTGSNKIADFEKVKGHKRFVYRILPTVDSITKAREAGVEIR
                     DLVAMLGPFSEEINLAMLRTFQADYLVTKDSGKAGGVEEKISAAESLGIVPIIITRDQV
                     ATKTWE"
     aSDomain        7217..7903
                     /aSDomain="TIGR00715"
                     /aSTool="tigrfam"
                     /description="precor6x_red: precorrin-6x reductase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg2_340_0007"
                     /evalue="9.00E-50"
                     /identifier="TIGR00715"
                     /label="ctg2_340"
                     /locus_tag="ctg2_340"
                     /protein_end="230"
                     /protein_start="1"
                     /score="167.6"
                     /tool="antismash"
                     /translation="IWIVGGTSESVALGKIFEEKNIPHLITYATKDGLELATDKAINKD
                     ESVEDFIVHKDIDTIIDLTHPFAVKMTDKVKKAAEKFQISYLRYERERVSYPADAILVD
                     SYEEAYDKLKDMSGTFFFTTGSNKIADFEKVKGHKRFVYRILPTVDSITKAREAGVEIR
                     DLVAMLGPFSEEINLAMLRTFQADYLVTKDSGKAGGVEEKISAAESLGIVPIIITRDQV
                     ATKTWED"
     CDS             complement(8022..9281)
                     /locus_tag="ctg2_341"
                     /transl_table=11
                     /translation="VSRDLALILLNIINPIAIYLIYAAFLGQPKYNKKIVFAVYFVFNF
                     ITTFVLLKASSSILNSIFFLGGMILLTFLYEGKIYFKIFIAFIIYIIFALEEISLYLIF
                     SSLDISLYNLDFEVDFVYVFIKISMLLIAFFINLNFNKFRNKTLPKYITIFLFIVPILS
                     IIIMVLETVRNPISDRFYALLVLFLLLINISIFVIFTILSNLYTDRLRLNNLEKDYDLI
                     NMQKENINKSTKRLAALEHDLKNKLIPLYYMAESEGNVGAYLSEIIGEFKNEFLIANSG
                     LIEVDAIINSKYEFCKENNIDFDVDLNISKDININHRDLAIILGNLLDNAIEASSKVAD
                     KWIRLVLKSEQNLVFIMVDNSFDGILKKKNGKLISRKNKEFSGLGLSNVEYLADKYGGK
                     VTISHKENKFRVSVILFEKK"
     PFAM_domain     complement(8037..8336)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_341_0013"
                     /evalue="5.20E-23"
                     /label="ctg2_341"
                     /locus_tag="ctg2_341"
                     /protein_end="415"
                     /protein_start="315"
                     /score="81.0"
                     /tool="antismash"
                     /translation="NHRDLAIILGNLLDNAIEASSKVADKWIRLVLKSEQNLVFIMVDN
                     SFDGILKKKNGKLISRKNKEFSGLGLSNVEYLADKYGGKVTISHKENKFRVSVIL"
     CDS             complement(9274..9996)
                     /locus_tag="ctg2_342"
                     /transl_table=11
                     /translation="LKIAICDDNKAFVDGLVKYLDKYQIEKCYDFEVDSYFSVEDLYQA
                     IQDKAYKLIFLDIEFPAASQSGIDLANKLRYVEKNFSSEIIFVSGSDSYFRDLLSFQPF
                     GFLEKPVAYKDLVKILDLFFSKAIVTRDVFTYKKSTTSFVLPYNEILYFASYNRKIKVK
                     TLDGSDSFYDRLDNIEKALNQEVFLRVHKSYIINTNFIKDYSLAHVSLINGESIAISTS
                     YAESFVLFLERKFGGESV"
     PFAM_domain     complement(9313..9570)
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_342_0015"
                     /evalue="4.40E-17"
                     /label="ctg2_342"
                     /locus_tag="ctg2_342"
                     /protein_end="228"
                     /protein_start="142"
                     /score="62.2"
                     /tool="antismash"
                     /translation="FVLPYNEILYFASYNRKIKVKTLDGSDSFYDRLDNIEKALNQEVF
                     LRVHKSYIINTNFIKDYSLAHVSLINGESIAISTSYAESFV"
     PFAM_domain     complement(9637..9990)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_342_0014"
                     /evalue="1.40E-11"
                     /label="ctg2_342"
                     /locus_tag="ctg2_342"
                     /protein_end="120"
                     /protein_start="2"
                     /score="44.6"
                     /tool="antismash"
                     /translation="IAICDDNKAFVDGLVKYLDKYQIEKCYDFEVDSYFSVEDLYQAIQ
                     DKAYKLIFLDIEFPAASQSGIDLANKLRYVEKNFSSEIIFVSGSDSYFRDLLSFQPFGF
                     LEKPVAYKDLVKIL"
     CDS             complement(10001..10570)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_343"
                     /sec_met_domain="AgrB (E-value: 3e-30, bitscore: 100.7,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNSSLIVKKLIEKNILDEANKDIYEYGSFIIFNYFVLYLTAYIV
                     CRVYLLNYDLLYFLSIILLFRSYTGGFHFKNYYYCLFTSIMELFFIAFLLKNLNLNTNI
                     LLVLIIIFSIFIFLFAPVDTKNRRLDVNERRKIKKKVLIILTCGLLLSFLFFIMCYEEL
                     LLVYFLSLSHCLILLIFGIIDNKIRM"
     PFAM_domain     complement(10031..10555)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_343_0016"
                     /evalue="1.20E-28"
                     /label="ctg2_343"
                     /locus_tag="ctg2_343"
                     /protein_end="180"
                     /protein_start="5"
                     /score="99.8"
                     /tool="antismash"
                     /translation="LIVKKLIEKNILDEANKDIYEYGSFIIFNYFVLYLTAYIVCRVYL
                     LNYDLLYFLSIILLFRSYTGGFHFKNYYYCLFTSIMELFFIAFLLKNLNLNTNILLVLI
                     IIFSIFIFLFAPVDTKNRRLDVNERRKIKKKVLIILTCGLLLSFLFFIMCYEELLLVYF
                     LSLSHCLILLIF"
     CDS             complement(10567..10710)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_344"
                     /sec_met_domain="TIGR04223 (E-value: 4.2e-09, bitscore:
                     32.1, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVLISKFLSVFLLKIVRHNLNSVCVGILYQPDISKISSKIKNLD
                     RL"
     aSDomain        complement(10603..10701)
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg2_344_0008"
                     /evalue="2.10E-08"
                     /identifier="TIGR04223"
                     /label="ctg2_344"
                     /locus_tag="ctg2_344"
                     /protein_end="36"
                     /protein_start="3"
                     /score="32.1"
                     /tool="antismash"
                     /translation="LISKFLSVFLLKIVRHNLNSVCVGILYQPDISK"
     CDS             10927..12264
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_345"
                     /sec_met_domain="PF04055 (E-value: 1.9e-15, bitscore: 53.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 4.1e-11, bitscore: 39.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.1e-13, bitscore:
                     47.1, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVSKFNHYYNCDGEIFIYNARTTALANIEKEKFEALSKFTSDNS
                     TKLDNDFIKDLEFGGFILPKDVDELDILKEEVFRSRMNTDSFGLTIAPTLACNFKCPYC
                     YEREVTDCSLMTEEVQEKIIEFIEAKIPTINHLSISWYGGEPLLKKEIIENLSEKIIKL
                     CEENNVSYHAGITTNGYFLDKDTLEMLHKNKVNSIQVPLDGMKDNHDETRFISKDRGSF
                     DKIIENLLSVKDLYQDEKENYPRINIRVNITRKNHKDIYDLVDLFKEKGLNEYVGMYIA
                     KIDDPLDTNYEYTLTNEEFIKLQNDFSKIIPKDKDEDVFWKYYPDRITASCCCDSISAF
                     VVDPKGRLYKCWEEIGHEEYSLGDLINGRKKYYPKNYYKYLLDTSITNEKCSKCSILPV
                     CMGGRCPYRIANNTALSCKEMEDTFNYWMNNSFKSLNKKDIRKISI"
     PFAM_domain     11203..11718
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_345_0017"
                     /evalue="2.10E-14"
                     /label="ctg2_345"
                     /locus_tag="ctg2_345"
                     /protein_end="264"
                     /protein_start="92"
                     /score="54.3"
                     /tool="antismash"
                     /translation="PTLACNFKCPYCYEREVTDCSLMTEEVQEKIIEFIEAKIPTINHL
                     SISWYGGEPLLKKEIIENLSEKIIKLCEENNVSYHAGITTNGYFLDKDTLEMLHKNKVN
                     SIQVPLDGMKDNHDETRFISKDRGSFDKIIENLLSVKDLYQDEKENYPRINIRVNITRK
                     NHKDIYDLV"
     aSDomain        11926..12162
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg2_345_0009"
                     /evalue="5.80E-13"
                     /identifier="TIGR04085"
                     /label="ctg2_345"
                     /locus_tag="ctg2_345"
                     /protein_end="412"
                     /protein_start="333"
                     /score="47.1"
                     /tool="antismash"
                     /translation="CDSISAFVVDPKGRLYKCWEEIGHEEYSLGDLINGRKKYYPKNYY
                     KYLLDTSITNEKCSKCSILPVCMGGRCPYRIANN"
     CDS             12334..12537
                     /locus_tag="ctg2_346"
                     /transl_table=11
                     /translation="MKYIVNPFDATTSDCECNCLVNCKCNGPAGNVCAPHGDNSCVVKC
                     ETKCSNNCTGTNSVASPTSFNF"
     CDS             12588..13973
                     /locus_tag="ctg2_347"
                     /transl_table=11
                     /translation="MYLELKSFFSNKIIRLVLIASIILSCFYVYTVIENGDNVDNSINN
                     TRREIVNNKKYYDDIVTSIEMYTPEKYRYLKDEYIKSLDWEIKADERYLDLLLDGYRKN
                     EKGLRKLIIYFNLYYMAIQTDYERGYEYPTQVFKDEIENYLDLSELPFDLYALEDLHNV
                     SWSNVNNKESEEDRESLHRAYEENKKGVERKFFLYKNNLREVDETSLSPWTYLAYIYSY
                     TSTKTQIFLPLIILLASYLMIFCRKEKSLDLIKLKADKKSKIYSHYLKIILSLSLIILL
                     VPDLLAILFMGIKNGFYGLKNPIGIYVEGLRFFNPYEHIFSGAGTRGLGLVYGIGYYPD
                     GYVMAFPGLSNIEFYKFLLLSIVPSILKLVFFISLGVSIGLLIKNTTISLLVSSLITLF
                     TVLSASLNALKTPYNIFSLDSGWNITLGHTNFSWLGSVLGLSLGIIVVLVVSLVVLNKK
                     ELD"
     CDS             14083..14280
                     /locus_tag="ctg2_348"
                     /transl_table=11
                     /translation="MKYIVNPFDATTSDCNCNCSSACNCNCTIANVKVCDPNICALCES
                     NCINNCTGTNSVASPTSFNF"
     CDS             14331..15716
                     /locus_tag="ctg2_349"
                     /transl_table=11
                     /translation="MYLELKSFFSNKIIRLVLIASIILSGFYVYTVIENGDNVGNSINY
                     IRRDIVEYKKYYDDAVTSIEMYTPTNYRYLKDEAIKARTWEIEARERKLDLLLDGYRKN
                     EQELRKLSIYFNLYYMSLQADYENGYKYSTQVFKDEIENYLDLSELPFDLYALEDIHNV
                     SWSNINSIESEEYREALHKAHEEQRKTLERDFFLLKNNLREVDSASLSPWTYLAYTYSS
                     KLTKVQLFVPLLIMLSTYMLIYARKEKSLDLIKLKADKKSKIYTHYLKIILSLSLIILL
                     VPDLLAIIFMGIKNGFYGLKNPIGIYVEGLKSLYPYENLGIGARVRGLGQVNGIGYYPN
                     GDIIEFPRLTNIEFYKFLLLSTVPSILKLVFFISLGVSIGLLIKNNTISLLVSSLITLF
                     TVLSASLNGLKTPYNIFSLDSGWNITLGHTNFSWLGSVLGLSLGIIIVVAVSLLVLNKG
                     ELD"
     CDS             15824..16042
                     /locus_tag="ctg2_350"
                     /transl_table=11
                     /translation="MKYIVNPFDVTTSDCTCNCSSACHCQCTVALNDTNICGDRDCRFY
                     CERNCESNCSNNCTGTNSVASPTSFNF"
     CDS             16093..17481
                     /locus_tag="ctg2_351"
                     /transl_table=11
                     /translation="MYLELKSFFSNKIIRLVLIISIILSIFMVYNIFENGDRSEGAINY
                     LRQEIVTDKKYYDDKITSIEMYTPDKYRYLKDEYIKSKDWEIETQERRLDLYLDGYRKN
                     EQELRKLSIYFNLYYMAIQTDYERGYEYPTQVFKDEIENYLDLSELPFDLYALEDLHNV
                     SWSNVNSFIRKEIDREELHDGYEVNKKKLERDFFLYKNNLREVDNKSLSPWTYLAFTYS
                     FKLNKVQLFVPLLIMLSTYMLIYSRKEKSLDLIKLKADKKSKIYTHYLKIILSLCLIIL
                     LVPDLLAILFMGIKNGFYGLKNPIGMYVEGLKSLYPYENISSGASIRGLGLIVGTGFNS
                     LGHLIDFLGLTNIEFYKFLLLSTVPSILKLVFFISLGVSIGLLIKNNTISLLVSSLITL
                     FTVLSANLYGLKTPYNIFSFDSGWNITLGHTNFSWLGSVLGLSIGIIIVVSVSLLVLNK
                     KELD"
     CDS             17587..17799
                     /locus_tag="ctg2_352"
                     /transl_table=11
                     /translation="MKYIVNPLNIGKNGDCNGINFCNCNFLKDCSDKKEKPCKNFIPCG
                     SKCDALCTSDCSGTDSVNSPSSFNF"
     CDS             17849..19234
                     /locus_tag="ctg2_353"
                     /transl_table=11
                     /translation="MYLEIKSFFSNKIIRLILIASIILSVFMGYYILESGDKLESTINH
                     IRQNIVTFKKNYDDKVTSIEMYTPKKYRYLKDEYIKSMDWLIEVEESRVDLLLDGYRKN
                     ENELRKLWIYLNLYYMSLRADYESGYGYSTQVFKDEIENYLDLSELPFDLYALEDLYNV
                     SWSNVNNKESEEDIDLLHIAYEEERKTLEREFFLLKNNLREVDFINLSPWTYLFYTYSF
                     ISTKVQLFVPLLIMLSTYMLIYSRKEKSLDLIKLKAEKKSKIYTHYLKIILSLSLIILL
                     VPDLLAIIFMGIKNGFYGLKNPIEIYKEGLKSLQPYQNIGIIANIRGLGLISATGFFSS
                     SDPIGFLGLENIEFYKFLLLSFIPSLLKLIFFISLGVSIGLLIKNNTISLLVSSLITLF
                     TVLSASLNGLKTPYNIFSLDSGWNITLGHTNFSWLGSVLGLSLGIIIVIFVSLLVLNKK
                     ELD"
     CDS             19337..19549
                     /locus_tag="ctg2_354"
                     /transl_table=11
                     /translation="MKYIVNPLNIGTNGDCNGINFCNCNNLKYCSNKEEDSCDNFIPCV
                     SNCESKCSNNCIGTNSVASPTSFNF"
ORIGIN
        1 agacggagac cactattaca acattgcaga agctttaaaa gttatggaag ataagggtat
       61 caaagatatt tttgtcctaa gcctttatgt tatcgaaggc catgaataca acaaggtaat
      121 aaaaatggct gaagactata atgctgatgg caggttaaat attaaatttt ccaaaggtct
      181 tttctcagac gatgctgaca tagaaaaagt tggagaattt tttagccact taaaagacaa
      241 gtcatctgct gaagccctag tttttatggg ccacgggtcc ttccacgacg aagacgaaaa
      301 atatggcaag cttcaagctt atttagacca aagaggcgta aaagttttta taggaacagt
      361 tgaaggttca attgtccttg aagacataat ggctagactt gaaaaagaaa atataaagtc
      421 agttgaagtc tatcctctaa tgttagtagc aggagaccac gttcaaaacg acatggcagg
      481 agacgaagac gactcttgga agtctgtact aagaaaggca ggctttgacg caggcgtttc
      541 tgttaaaggc ctttgcgaat acgatgactt taacgacttg tttataggaa aacttagaga
      601 aatcctatga agaccatcca aataactgcc ccagcttcaa actctggaaa gactataaca
      661 acgtcaatta tagccagggc cctaaaaaac cgcggcttag acctagttgg ttttaaatgt
      721 gggccagact ttattgactc taagtacctg gcctttgcta gcaagaaaga caacggcaac
      781 ttagacgtcc acctttgtgg gactaaagga atgaaacatg cccttgcttt aaacaaggga
      841 gcctacgcaa ttgttgaagg ggccatgggc tactttgatg gcattggcct aggctatgag
      901 gcatcagcct atgacattgg aaggacctta gaccttccag gaattttagt ttacaagccc
      961 cagggagaaa tgtttacaat agttccaaag gtcaagggca tggtagacta ctctcaaggc
     1021 cgcctcaagg gaataatttt ttctgcaaca accaagacca tgtacggcta tttgaaaaaa
     1081 atgttagaag accatgtgga cattaaggtc ttaggctata tagaaaaaga cgaagactta
     1141 aactttgggt ctagaaacct tggcctaatg ctaccagaag aattagaaga atttgataat
     1201 attttagatg cccaagctaa aaaatctgaa gagacaatag actatgaaag tctaatagat
     1261 ctaatggcag atataaatgt agatcaaggt atggaagaga ttaaaaaaac tccctatact
     1321 attgccatag ctagggatca ggccttttgc ttccactatg gagaaaatat taagctcttt
     1381 gaaaaatatt ttacagtaaa atacttttct ccactaaggg acaagacctt gcctgaggca
     1441 gaccttgtct atattgacgg tggctatccg gaaatttata tagacgaact tgcagcaaac
     1501 aagtctatgc ttaaaagtgt tagagcttat atagaagctg gtggatttta tcttggccaa
     1561 ggagcaggac ttttgtattt aactgaaaac ctagatggca gggacctagt aggaattttt
     1621 aagacccagt cccaaatgac taataggctg caaaactttg gctatgtaaa tttaatttta
     1681 gaagaagatt tacttttagg agattcgggg actctaattc cagcccacga gtttcactat
     1741 tcaaaaatcg aagagaattt accagccagc ataagggttg aaaaggcatc aaagttaaaa
     1801 acttggtcag gaggctataa gtacaaaaac gccctaggcc tttaccaaca cataaacttt
     1861 gctggcaatg aaagtgtaat tgaccatata ataaaaaaat taggagaaga aaatgtatat
     1921 aaataatccc atggaaattg aaaacaaatc aatggacata attgaagaag gtttaaataa
     1981 gacaaatttt acagaagaag aaaaaattgt agttaaaagg accattcata caactggcga
     2041 ccttgactac caaaacattg tagactttaa agaagacttt gttaatgttg caaaaaattc
     2101 tttaaagaac aaggtgaaga tttatacaga tacaaatatg accaaggctg gagtaaacaa
     2161 aaaggccttg gaaaaacttg gcctagaaat tgtctgctat attgccgacg aagatgtagc
     2221 taagaaggcc aaggaagagg gaacaactag aagccaggca gccattgaaa aggctattaa
     2281 agaaggggtg acttgctttt caattggcaa cgccccaaca gccctctata aattattaga
     2341 agaatacgat gcaggcaggg caaaggttga ctttgtaatt ggagttccag ttggttttgt
     2401 tggagcagca gaatcaaaag aagacctaag aggctataaa attcctcaag ttacaaccat
     2461 aggcaacaag ggcggctcaa atgttgcagc ctcaataatc aatgccctta tgtatatgtt
     2521 agttgaaaga tgaaaaaact agacctttat attgacaagg acggggaaaa acttcgctgt
     2581 ggttatacaa ctggatcaac tgcaactgga gccaccaagg cagcagctat aatgctcctt
     2641 agccaaaggg aaatttctga aattaaaata aaaactccag caggcgtaga cctagaccta
     2701 gaagttgagt cagcagaaat aggaaaagac tatgccatag cctctgtgaa aaaagattct
     2761 ggtgacgacc cagacgcaac caaggaagta gaaatttttt ccaaggtctc cttaagagat
     2821 gatggggaaa tttttataac agggggacca ggagttggaa gaattaccca aaagggaatt
     2881 tacggagata ttggcgacta tgcaataaat ccagttccta ggcagatgat ggaaagagaa
     2941 cttttagacc taggagaaga cactggctac aatgtagaaa tttttattcc ccaaggtgaa
     3001 gagatttcaa aaaggacctt taacaaaaac attggcattg aaggtggcat ttcaattatt
     3061 ggcaccaagg gcattgtcta tccaatgagc gaagaagccc tactaaagtc aatttatatg
     3121 gaaatcgaat ctataaaatt aaagcaggga acagaaaaaa ctctgatgct aactccaggt
     3181 aactatggcg aagaatatgc aaaaaagtta ggagacgaca taaaagttgt ccaagtttct
     3241 aactatgtag gcaggtgttt aaagtacgcc tacaaggcag gctttagaga ctttttcctc
     3301 cttggccata taggaaaatt ttcaaaatta tctatgggag cctttaacac ccacaacgaa
     3361 acagttgacc tgcgcatgga ggcctttgtc tactatctag ccttaaaagg cgtggaccta
     3421 gaccatttaa aaaccataga taagtttcta actgcagaag aggcgtcaaa gtatattttc
     3481 gaaaataact tagactttgt ctttaaagac atggaagcag gctgccaaag aaggataaaa
     3541 aaatacctaa aagacgatca aataaaggtt caagtaaaaa tgtattcaat gagtagaggt
     3601 atgctaagtg attaaactaa taggagcagg acctggtaac attaacttgt taaccctcca
     3661 ggccctagat gagataaaga cagcagataa agtcatagcc tttgaaagaa ttgccaagga
     3721 ccttcacagc ctaagacctg acattattgt tataaaaaga gtagaccaag tcttagacca
     3781 gctagaaaaa attggcggag atgagactgt agctattatg gcttcagggg attcttgttt
     3841 ttttggaatt atagatctct taaagagaaa gggagttgag atagaagaag tcctagttgg
     3901 aatttcttct gttcaatact ttttcaacag gctacaaaag tcttattcca gtctagagac
     3961 taggtcagtt cacggcagag actttgattt ttctacaatt gataaagata aaaaatattc
     4021 tttcttaatt gaccaagaaa aaaatgccaa ctatatttca aaaaaattaa aagaccaggg
     4081 cctaagtgga aaaatctact gtggctacaa tctttcttat gacgacgaaa aaattttaac
     4141 aataaatatt ggagatcaaa tagacgagcc ttcaatattg ggagtagtgg tggtggaatt
     4201 taatgtggat taaagacgaa gaatttatta ggggccaggt ccctatgaca aaattttctg
     4261 tccgcagtct tataatagca aatcttgccg taaaagatga cgacaggctt ttagatatag
     4321 gctgtggaac aggatcaatt tctgtagaag ctgcctgcca tggagcgaca gtttttgcag
     4381 ttgataaaaa cccagaggca gtgagcctaa ctaaagaaaa tgcaaaaaaa ttcgaccaag
     4441 acatagaagt tctagagaga aatgttccag acggccttga cgacataaaa ataaacaagt
     4501 gctttgtcgg tggatcaact ggcaggctag aagatatatt ttcttattta gaaaaaaact
     4561 tagaagcagg cggagttctt gtagggtctt ttatactttt aaaaaatctt tttgagttta
     4621 aagagctgtt gaaaaaatac gcctacaagg acctggaagt aaacttagtc caagttgcta
     4681 cagaagataa gataggacta atgagaggag aaaatcctat ttttatagta aaaggagtta
     4741 aagtatgata cattttgttg gagcaggacc aggaaatcct gacttaataa ctataagagg
     4801 cagggacctt ttagaaaaag cagatatatt aatttgggct gggtcactag tatcaccaga
     4861 ccatttaaaa tacaccaagg agtcatgtga aatctacgac tccaagggca tgaacctaga
     4921 cgaagttata gaagtaatgc taaggggcca tgaagaaggc aaggaaattg tccgccttca
     4981 cactggcgac cctacaattt atggagccat tagagaacaa atggacaggc tagaagaagc
     5041 aggcattgag tacgaagttg tgccaggagt ttcatctttt acaggagcct gtgcagccat
     5101 aaaaagagaa tttacactac caggagtttc tcaaacagta attctaacta gaaacgctgg
     5161 cagaactcca gttccagagg gagaagagtt agaaaaatta gccagtcaca aggcgtcaat
     5221 ggcaatattt ttgtcagtcc aagacataga ctctgtagtt gaaaaactaa aaaaaggcta
     5281 tgggtcagga gacgtgccag tggccattgt ctttaaggca acttgggacg accaagaaat
     5341 tctatatggc accttagaca caatttctga tcaagtaaaa aaggccaaca ttaaaaaaat
     5401 gagccaaatc ctagtaggaa actttataga aggagactat gaactttcta aactttatga
     5461 caagcacttt acccataaat ttagaaaagg catagaggaa aaatgataaa aatattttct
     5521 tactctcaag ctggcctaga ccttggagaa aaaataaagg actttttgtc agctgaccac
     5581 tataataaaa gaattactgc ctttgatgta aaaataattt taaaagaaaa ctggcaggca
     5641 gctgaagcct ttatatttat ttcttcaact ggcattgcag ttaggatgat aaaggacttt
     5701 ataaaagcca aggaccaaga tccagcaatt atagttatag acgacacagg aaaaaatgta
     5761 atttcacttt tgtcaggcca cctaggtggg gccaacgact tgactcggac tctagcagaa
     5821 tttttaggag ccaatccagt cattacaaca tcaactgaca accacggcat tgaagcagta
     5881 gacagttttg caaggaccaa cgactacagg ctggcagata aaaataaaat cctgccgatt
     5941 tcaaagttaa tgctagaagg aaagactatc ggtttttatt cagaagttga caaggtcatt
     6001 gattacaatc acataaaagt tttagaaaat ctagacgatc tttcgggctt agacgggcta
     6061 attgtagttt ctaataaaat agaaagagac cttcctatcc ctagtattta tttacaccca
     6121 aaaaatctta acctaggtat tggctgtagg agagatacgc caggagaaaa aattatttcc
     6181 tttataaaag accagcttaa tgaccttggc ctatcatttt atagcataaa aaaaattggc
     6241 tcagttgaag caaaaagaga cgaagttggc atccaagagg cggcagacta ttttaaagta
     6301 gagaagaaaa ttttttcaaa cgatcaaata aaaacagtag aagacaaatt tgataaatca
     6361 gactttgtta aaaagaccat tggagtttat tcagtggcag agccttgtgc atacctactt
     6421 ggtggcaggc ttttaacaaa gcgactaaaa aaagatggca taacccttgc cataagtttg
     6481 gaggacaaat gaaaaaatta tatgtaattg gaataggccc aggtggcaag gaaagaatga
     6541 cccaagaagc cttggcagct atagaaaaat ctgatgttat agttgcctac acaccatatt
     6601 tagaatatgt aaaagactat ataaaagaca aagagacctt tacatcagga atgagaaaag
     6661 aagtagaaag atgtcaaaag gccatagact ttgctagaga aggcaagaca acttcgattt
     6721 tatcaacagg agacgcaggc ctttatggca tggcaggacc aattttagaa ctcctaaagg
     6781 gagacgagga agttcaggta gaaattgttc caggagtttc tagcgttttt tctgcagcag
     6841 cagaacttgg cgccccagtt atgcacgact tggcaataat ttccctatca gacctaatga
     6901 caccatggga tcttattcaa aagcgcattg acctagcagc ccaaggggat tttgtcatta
     6961 gcttgtataa cccaaggtcc aagggtagac cagaccacct tcaaacagcc atagaaataa
     7021 ttttaaaaca caagagccca gacactccag ttggagttgt aaaaaattct ggcagagaaa
     7081 acaaagaaca gtgggtcaca accttaaaag acctagacta tgaaaaagtt gacatgctga
     7141 caattttaat aattggcaac aaggcttcct atatagacgg agacaaaatt ataactccaa
     7201 gaggctatga aatatgattt ggatagtagg tggaactagc gaatcagtag ccctaggaaa
     7261 aatatttgaa gaaaaaaata ttccccacct aataacctat gccaccaaag acggtctaga
     7321 actggcaaca gacaaggcca ttaacaaaga cgagtcagta gaagacttta tagtccacaa
     7381 ggacattgac acaatcatag acctgaccca tccctttgct gtaaagatga cagacaaggt
     7441 gaagaaggca gcagaaaaat ttcagatcag ctacttgaga tacgaaagag aaagagtttc
     7501 ttatccagct gacgcaattt tagtagactc ttacgaagaa gcttatgaca agttaaaaga
     7561 catgagtgga acatttttct ttacaactgg gtctaacaag atcgcagact ttgaaaaggt
     7621 aaaaggccac aagagatttg tctataggat cctaccgaca gtagactcaa taactaaggc
     7681 cagagaggca ggagttgaaa taagagacct agttgcaatg ctagggccat tttcagaaga
     7741 aataaacctg gccatgctaa ggaccttcca ggcagactac ctagttacta aggactcagg
     7801 caaggcaggt ggcgtagaag aaaaaatttc tgcagcagaa agcctaggca tagtgccaat
     7861 aataataacc agagaccaag ttgcaacaaa aacttgggaa gactttttat tagaagtaga
     7921 aaaattccta tccattaaaa aaagcaggac ctagaaaagt aggttctgct ttttgctata
     7981 aaactttata aacttatatc atattaaaaa tccaattctc tttatttctt ttcaaacaag
     8041 attacactga ccctaaactt attttcctta tgacttatgg tgaccttgcc tccgtactta
     8101 tcagctaggt attctacatt ggaaagacct aggccagaaa attctttgtt ctttctagaa
     8161 attaatttgc catttttctt ttttaaaatg ccgtcaaagg aattatctac cataataaaa
     8221 actaggtttt gttcactttt caacactagc cttatccact tgtcagccac ttttgaagac
     8281 gcttctatag cattatctag taggtttcct aaaataattg ccaggtctct gtggttaata
     8341 ttaatgtcct tagaaatatt taggtctaca tcaaaatcta tattattttc cttacaaaat
     8401 tcgtatttag aattaataat ggcatcaact tctataaggc cactatttgc aattaaaaat
     8461 tcgtttttaa actcgccaat aatttcagat aggtaggcgc caacattgcc ttcactttca
     8521 gccatataat aaagaggaat gagcttgttt tttaggtcat gctccaaggc tgccagcctc
     8581 ttagtggact tgtttatatt ttccttttgc atattaataa ggtcatagtc tttttctaag
     8641 ttgtttagtc ttagcctgtc ggtgtaaagg ttagagagaa tagtaaaaat cacaaagatt
     8701 gaaatattaa ttagcaagag aaataaaact aaaagagcat aaaacctatc agaaattgga
     8761 tttcttactg tttctaaaac cattattatt atactcaaaa taggaactat aaataggaat
     8821 atagttatat atttaggtag tgtcttattt ctaaatttat taaaattgag atttataaaa
     8881 aatgctatta agagcattga aattttaata aagacataaa caaaatcaac ctcaaaatct
     8941 aaattataaa gtgaaatatc taaagaagag aaaataagat ataaagaaat ttcttctaat
     9001 gcaaatataa tgtaaattat aaaggcaata aaaatcttaa aatatatctt tccttcatat
     9061 aaaaatgtaa gcaaaatcat tccacctaga aaaaatattg aatttaaaat tgaagatgaa
     9121 gcctttaaca aaacaaaagt agtaataaaa ttaaaaacaa aataaacagc aaaaactatt
     9181 tttttattgt acttgggctg gcctaaaaag gcagcataaa ttaaataaat agctatagga
     9241 ttgataatat ttaaaaggat aagggctaag tctctagaca ctttctccac caaactttct
     9301 ttctaaaaat aaaacaaaac tctcagcata gctagttgaa atagcaattg actcgccatt
     9361 aataagacta acatgggcca aagaatagtc tttaataaaa ttagtattta taatatagga
     9421 cttgtggacc cttaaaaaaa cttcctggtt caaggctttc tcaatattat ctaagcggtc
     9481 ataaaaagaa tcactgccat ctagggtctt caccttaatc ttcctattat aactagcaaa
     9541 atataaaatc tcattataag gcagaacaaa agaagttgta ctctttttgt atgtaaaaac
     9601 atccctagta actatggcct tagaaaaaaa caaatctaaa atcttcacta ggtccttata
     9661 ggccacaggt ttttctaaaa acccaaaagg ctgaaaggaa agaagatctc taaaataact
     9721 atcagaccca gagacaaaaa ttatttcact agagaaattt ttctctacat atctcaactt
     9781 gttagcaagg tctatgccac tttggctagc ggcaggaaat tctatatcta aaaatattaa
     9841 cttataggcc ttgtcctgta tagcctgata aaggtcttct acagaaaaat aagaatccac
     9901 ttcaaaatca tagcattttt caatttgata cttgtccaga tattttacta acccatctac
     9961 aaaagcctta ttgtcatcgc aaatagctat tttcaaaaaa tcacatcctt atcttattat
    10021 caattatacc aaagataagt aaaataagac aatgagacaa agataaaaaa taaaccaaaa
    10081 gtaattcttc atagcacatt ataaaaaata aaaaagacaa taacaaacca caagttaaaa
    10141 ttataagaac ttttttctta atttttcttc tttcatttac atcaagtctt ctatttttag
    10201 tatctactgg agcaaataga aatataaaaa tagaaaatat aataattaac acgagtagta
    10261 tattcgtatt caaatttaga ttttttaata aaaaagctat aaaaaatagt tccattatag
    10321 aggtgaaaag acaatagtag taatttttaa aatgaaaacc acctgtataa gatctaaata
    10381 gcaatattat tgataaaaaa tataataagt cataattaag gagatatact ctacatacaa
    10441 tgtaagcagt caaatataaa acaaaatagt taaatataat aaagctacca tattcatata
    10501 tatctttatt tgcttcatca agaatatttt tttctattaa ttttttaact attaatgatg
    10561 agttgttcat agcctatcta aatttttaat tttacttgaa atttttgaaa tatcaggctg
    10621 atataaaata cctacacaaa cagaatttaa attatgcctt acaattttta acaaaaaaac
    10681 agataaaaat tttgaaatta ggacactcat aattacctcc gtaaaattat attttattgc
    10741 ttttaatttt attatattac aaagaaatta acataaaaat gttgaaaaaa ggcacaaaaa
    10801 tgttgaaatt aatttaaatt caacaaaaat acctgttttt tcaacatttt tgaaaaatta
    10861 aatatatcag tggtatctta taattaacaa gaaattagaa tcttaaaaaa taatatggag
    10921 gtcaaaatga aagtatcaaa atttaatcac tattataatt gtgacggaga aatatttatt
    10981 tataatgcca gaacaacagc tcttgcaaat attgaaaaag aaaaatttga agctttaagt
    11041 aaatttacca gtgataattc tactaagtta gataacgatt tcataaaaga cttagagttt
    11101 ggaggcttta ttttgccaaa agatgtagat gaactagata tattaaaaga agaagttttt
    11161 agatctagaa tgaatacaga ttcctttggc ctaacaatag ctccaacttt agcttgtaac
    11221 tttaaatgtc cttattgtta tgaaagagaa gttacagact gtagccttat gactgaagag
    11281 gtccaagaaa aaataataga atttatagaa gcaaaaattc ctacaataaa ccaccttagt
    11341 atctcttggt atggaggaga acctctatta aaaaaagaaa tcatagaaaa tctcagtgag
    11401 aaaataataa aactatgtga agaaaacaat gtaagttacc acgcaggaat aacaacaaat
    11461 ggatactttc tagacaaaga caccctagaa atgttacaca aaaataaagt aaactctatc
    11521 caagttcccc tagacggaat gaaagataac catgacgaaa ctaggtttat ttctaaagac
    11581 aggggaagct tcgataagat aatagaaaac ctactgtcag ttaaagatct ctaccaagac
    11641 gaaaaagaaa actatcctag aataaatatt agagtaaata taactagaaa aaatcacaag
    11701 gacatatatg acctagtaga cctcttcaaa gaaaaaggcc tcaatgaata tgtaggaatg
    11761 tatatagcaa aaattgatga ccccttagat acaaactatg aatatacact aacaaatgaa
    11821 gaatttataa aactacaaaa tgatttttca aaaattatac caaaagacaa ggacgaagat
    11881 gtattttgga aatactatcc agatagaata acagcaagtt gttgttgcga tagcatatct
    11941 gcctttgtag tagatccaaa aggtaggctg tataaatgct gggaagaaat aggccatgaa
    12001 gaatatagtc tcggcgacct aataaatggc agaaaaaaat attatccaaa aaattactat
    12061 aagtacttat tagatacatc aattacaaac gaaaaatgta gtaaatgtag catactgcca
    12121 gtttgtatgg gtggaagatg cccatataga atagcaaaca atacagccct aagctgtaag
    12181 gaaatggaag atacctttaa ttattggatg aataactcct ttaagtctct taataaaaaa
    12241 gacattagaa aaattagtat ttaactaggt taataacaca ctgctagaat actgtaagta
    12301 tataaaaata aaaacttaaa caggaggtat attatgaaat atatagtaaa tccttttgat
    12361 gctactacaa gtgactgtga atgtaattgc ttagttaatt gtaaatgcaa tgggccagct
    12421 ggaaatgttt gtgctcctca tggggataat tcgtgtgttg taaaatgtga aactaaatgt
    12481 tcaaacaatt gtactggtac aaactcagta gcatctccaa catcttttaa tttctaagaa
    12541 gtaaaataaa acgtagcagt gtgttattat ataaatgagg tgatagaatg tacttagaat
    12601 taaaatcatt tttttcaaat aaaattataa ggctagtttt aatagcatca ataatcttgt
    12661 cttgctttta tgtctataca gttattgaaa acggagacaa tgtagataac tctattaata
    12721 atacaagacg agaaatagtt aataataaaa agtattatga tgatatagtt acaagcatag
    12781 aaatgtatac tccagaaaag tatagatatt taaaggatga gtatattaag tctttggact
    12841 gggaaataaa agctgatgaa agatatttgg acttattgtt agatggttat agaaaaaatg
    12901 aaaaagggtt acgaaaacta ataatatact ttaacttata ttatatggcc atacaaactg
    12961 actatgaaag aggctatgaa tatcctaccc aagttttcaa agatgaaata gaaaactacc
    13021 tagatctttc agagcttccc tttgacttat atgctctaga agacctccac aatgtaagtt
    13081 ggtctaatgt taataataaa gaatcagagg aagatagaga atcgcttcat agagcctatg
    13141 aagagaacaa aaaaggtgta gaaagaaaat ttttcctcta taaaaataat ttaagagaag
    13201 tagatgaaac aagcttgtct ccatggactt atttagctta catttactca tatacttcaa
    13261 ctaagactca aatatttctt cctttaataa tattattagc tagttatctg atgatttttt
    13321 gtaggaagga aaagtcccta gacctaataa aattaaaggc agataaaaaa tctaaaatct
    13381 atagccacta tctaaaaata atcctaagtc ttagtttaat aatcttatta gttccagacc
    13441 ttttggcaat tctatttatg ggcataaaaa atggtttcta tggcctaaaa aatccaatag
    13501 gtatatatgt agaaggatta aggttcttta acccttacga acacatattt tcaggagctg
    13561 gtactagagg attaggacta gtatatggca taggttatta tcctgatgga tatgtaatgg
    13621 cattcccagg ccttagcaat atagaatttt acaaatttct ccttctatcc attgttccaa
    13681 gtattttaaa attagtattt tttatctctc ttggagtttc tataggccta cttataaaaa
    13741 atactaccat aagcttactt gtaagttctc taataacttt atttacagtt ttatctgcaa
    13801 gtttaaatgc tctaaaaact ccgtataata tattttcact agatagtggt tggaatatta
    13861 ccctaggtca tactaatttt tcttggctag gcagtgttct tggtcttagc ctaggaataa
    13921 ttgtagtgct tgttgtaagt ttagttgtct taaacaaaaa agaattagat tgagaaaaat
    13981 cataagaata aaatttagag aattaaatga tctcataaat aacacactgc taaagaaaat
    14041 caaatataaa ataaacataa acagaaaaca aggaggaaat ttatgaaata tatagttaat
    14101 ccttttgatg ctactacaag tgactgtaat tgtaactgtt catctgcttg caattgtaac
    14161 tgtacaatag ctaacgttaa agtttgtgat ccaaatatat gtgctctatg tgaatcaaat
    14221 tgtataaaca attgtactgg cacaaactca gtagcatctc caacatcttt taatttctaa
    14281 gaagtaaaac aaagcctagc agtgtgttac tatataaatg aggtgatagt atgtacttag
    14341 agttaaaatc atttttttcc aacaaaatta ttaggctagt cttaatagcg tcaataattt
    14401 tgtctggatt ttatgtctat acagtcattg aaaatggaga caatgtaggc aactcaatta
    14461 attatataag acgagatata gttgaatata agaaatatta tgatgatgca gttacaagta
    14521 tagaaatgta tactccaacg aattatagat atttaaaaga tgaggcaatt aaagctagaa
    14581 cttgggaaat agaggctaga gagagaaagt tagacttatt gttagacgga tatagaaaaa
    14641 atgagcagga gttacgaaaa ctatcaatat attttaactt atattatatg agccttcaag
    14701 ctgactatga aaatggatat aagtactcca cccaagtttt taaagatgaa atagaaaatt
    14761 atctagacct atcagagctt ccttttgact tatatgccct agaagacatc cacaatgtaa
    14821 gttggtctaa tattaatagt atagaatcag aggaatatag agaagcactt cataaagctc
    14881 atgaagagca aagaaaaact ttagaaagag attttttcct attaaaaaat aatttaagag
    14941 aagttgactc cgcaagtcta tctccatgga cttatttagc ctatacttat tcatctaaat
    15001 tgactaaggt tcagttattt gttcctttat taataatgct atcaacctat atgcttattt
    15061 atgctagaaa ggaaaagtcc ctagacctaa taaaactaaa ggcagataaa aaatctaaaa
    15121 tctacaccca ctatctaaaa ataattctaa gtcttagtct aataatacta ttagttccag
    15181 acctattggc aattatcttt atgggcataa aaaatggttt ttatggtcta aagaatccaa
    15241 taggtatata tgtagaaggc ctaaaatctc tttatcccta tgaaaattta ggaatagggg
    15301 ctagagttag aggcttggga caagtaaatg gcataggtta ttatcctaat ggagatataa
    15361 tagaattccc aagacttaca aatatagaat tttacaaatt tctccttcta tccactgttc
    15421 caagtatttt aaaattagta ttctttatat ctcttggagt ttctataggc ctactaataa
    15481 aaaataatac cataagctta cttgtaagtt ctctaataac tttatttaca gttttatctg
    15541 caagtttaaa tggtttaaaa actccatata atatattttc actagatagt ggttggaata
    15601 taactttagg tcatacaaac ttttcttggc taggcagtgt tctaggtctt agcctaggaa
    15661 taattatagt ggtcgccgta agcttattag tcttaaataa aggagaatta gactgagaaa
    15721 aagtataaga ataaaattta gagaattaaa ttaccccata aataacacac tgttaaacaa
    15781 tataaacgta taaaaaagaa aaacgtaaat aggaggaaat tttatgaaat atatagttaa
    15841 tccatttgat gttactacaa gtgactgtac ttgtaactgt tcatctgctt gtcattgtca
    15901 atgcacagtg gctctaaatg atactaatat atgtggagat agagactgca gattttattg
    15961 tgagagaaat tgtgaatcga attgttcaaa caattgtact ggcacaaact cagtagcatc
    16021 tccaacatct tttaatttct aagaagtaaa acaaagccta gcagtgtgtt attatataaa
    16081 tgaggtgatc gtatgtattt agaattaaaa tcattttttt ccaataaaat tataaggcta
    16141 gtattaataa tttcaattat tctatctatt tttatggtat ataatatttt tgaaaatgga
    16201 gacagatctg aaggcgcgat taattaccta agacaagaga tagtaacaga taagaagtac
    16261 tatgatgata agattacaag catagaaatg tatactccag ataaatatag atatctaaaa
    16321 gatgagtaca ttaagtctaa ggactgggaa attgaaaccc aagaaagaag attagactta
    16381 tatttagatg gatatagaaa aaacgaacaa gagctaagaa aactttcaat atacttcaac
    16441 ctatattata tggccataca aactgattat gaaagaggtt atgaatatcc tacccaagtt
    16501 tttaaagatg aaattgaaaa ctatttggat ctttcagagc ttccctttga cttatatgcc
    16561 ctagaagacc tccacaatgt aagttggtct aatgttaatt cttttataag aaaagaaata
    16621 gatagggaag agctccatga tggatatgaa gtaaataaaa aaaaattaga aagagatttt
    16681 ttcctctata aaaataattt aagagaagta gataataaaa gtttatctcc atggacttat
    16741 ttagccttta cctattcatt taaattgaat aaggttcagt tatttgttcc tttattaata
    16801 atgctatcaa cctatatgct tatttattct aggaaggaaa agtccctaga cctaataaaa
    16861 ctaaaggcag ataaaaaatc taaaatctac acccactatc taaaaataat tttaagtctg
    16921 tgcctaataa tactattagt tccagaccta ttggcaattc tctttatggg tataaaaaat
    16981 ggcttttatg gcctgaaaaa tccaataggt atgtatgtag aaggactaaa atctctttac
    17041 ccttatgaaa atataagctc aggagcaagt attagaggct taggtctaat agtgggaaca
    17101 ggatttaact cacttggaca ccttatagac ttcctaggac ttaccaatat agaattttat
    17161 aaatttcttc ttctatccac tgttccaagt attttaaaat tagtattttt tatctctctt
    17221 ggagtttcta taggattact aataaaaaac aacaccataa gcttacttgt aagttctctt
    17281 ataactttat ttacagtttt atcagcaaac ttatatggtc taaaaactcc atataatatt
    17341 ttctctttcg atagtggttg gaatataact ctaggtcata caaacttttc ttggctaggt
    17401 agtgttcttg gccttagtat tggaataatt atagtggtat ctgtaagttt acttgtctta
    17461 aataaaaaag aattagactg agaaaaagta taagaataaa atttagaaaa tggatcatta
    17521 cattaataac acactgctac gatactgtaa gcatataaaa ataaaaactt aaataggagg
    17581 tatattatga aatatatagt taatccatta aatattggaa aaaatggtga ttgtaatggg
    17641 ataaattttt gcaattgtaa ttttctgaaa gattgttccg acaaaaaaga gaagccgtgt
    17701 aaaaatttta ttccatgtgg aagtaaatgt gacgcacttt gtacatctga ttgttcagga
    17761 actgattcag taaactctcc atcttcattt aatttttagt tagcaaataa aacctagcag
    17821 tgtgttatta tataaatgag gtgaatatat gtacttagaa ataaaatcat ttttttccaa
    17881 taaaattata agactaatat taattgcatc aataattcta tctgttttta tgggctatta
    17941 tatccttgaa agtggggata aattggaaag tacaattaat catattagac aaaatatagt
    18001 tacatttaag aaaaattatg atgataaagt tacaagcata gaaatgtata ctccaaaaaa
    18061 gtatagatat ttaaaagacg agtatattaa gtccatggat tggttgattg aagtagaaga
    18121 aagtcgtgta gatttactat tagatggtta tagaaaaaat gaaaatgaat taagaaagtt
    18181 atggatatac ctaaatttat attatatgag ccttagagct gactatgaaa gcggttatgg
    18241 gtattctact caagttttca aagacgaaat agaaaactac ctagatcttt cagagcttcc
    18301 ttttgattta tatgccctag aggacctcta caatgtaagt tggtctaatg ttaataataa
    18361 agaatcagag gaagacatag acttacttca tatagcctat gaagaagaaa gaaaaacttt
    18421 agaaagagaa ttttttctat taaaaaataa tttaagagaa gttgacttta taaacctatc
    18481 tccatggaca tatttgtttt atacctattc atttatatca actaaggttc agctatttgt
    18541 tcctttatta ataatgctat caacctatat gcttatttat tctaggaagg aaaagtccct
    18601 agacctaata aaactaaagg cagaaaagaa gtctaagatc tacacccact atctaaaaat
    18661 aattttaagt cttagtttaa taatattact agttccagac ctattggcaa ttatttttat
    18721 gggaataaaa aacggttttt atggcctaaa aaatccaata gaaatttata aggaaggcct
    18781 aaaatctctt cagccttacc aaaacatcgg aattattgct aatattagag gcttaggctt
    18841 gatatctgca acaggatttt tttcttcatc tgatcctatt ggatttttag ggctagaaaa
    18901 tatagagttt tataagtttc tccttctatc ctttatacca agtcttttaa aactaatatt
    18961 ctttatttct cttggagttt ctataggctt actaataaaa aataatacca taagcctact
    19021 tgtaagttct cttataactt tatttacagt tttatcggca agtttaaatg gtttaaaaac
    19081 tccatataat attttctctt tagatagtgg ttggaatata actttaggtc atacaaactt
    19141 ctcttggcta ggcagtgttc ttggtcttag cctaggaata attatagtga tttttgtaag
    19201 cttacttgtc ttaaacaaaa aagaattaga ttgaaaaaaa gtgtaaaaat aaacaattaa
    19261 atgatctcat aaataacaca ctgccaaaga aaatcaaata caaaataaac ataaacagaa
    19321 aacaaggagg aaatttatga aatatatagt taatccatta aatattggaa caaatggtga
    19381 ttgtaatggg ataaattttt gcaattgtaa taatctgaaa tattgttcca acaaagaaga
    19441 ggactcgtgt gataacttta ttccatgcgt aagtaattgc gagtcaaaat gctcaaacaa
    19501 ttgtattggc acaaactcag ttgcctctcc aacatctttt aatttctaag aagtaaaaca
    19561 aaacttagca gtgtgttatt ataaaaatga ggtgacaata tgtatttaga gttaaaatca
    19621 ttttttttaa ataaaattat taagctagta ttaataattt caataattct atctattttt
    19681 acggtttatt atatttttga aaatggggat aacttagagg gcccaattaa tcatataaga
    19741 caagaaatag taacagataa gaagtattat gataatggag ttacaagcat agaaatgtat
    19801 actccaacaa agtatagata tttaaaggaa gagtttatta agtctatgga ctgggaaatt
    19861 gaagccgaag aaagaaaatt agacttatat ttagatggat atagaaaaaa cgagcgagag
    19921 ctgcaaaaac tatcaatata ctttaaccta tattatatgg ctctacaaac tgactatgaa
    19981 agaggttatg aatatcctac ccaagttttc aaagatgaaa tagaaaatta tctagacctt
    20041 tcagaccttc cctttgatct atatgcccta gaggacctcc acaatgtagg ctggtctaat
    20101 gttaattata gtatagaatc agaaatagat agggaagaac tacacgcagg ttatgaagta
    20161 aataaaaaaa atttagaaag aaattttttc ctctataaaa ataatttaag agaagtagat
    20221 gaaacaagtc tgtctccatg gacttatttg gcctatactt attcatttaa gtcgactaag
    20281 gttcagctct ttgttcccct actaataatg ctatcaacct atatgcttat ttactctaga
    20341 aaggaaaagt ctctagatct aataaaatta aaggcagata gaaaatctaa gatctacagc
    20401 cactatttaa aaataatttt aagtcttagc ttaataatat tattagttcc agacctactg
    20461 gcaattctct atatgggcat aaaaaatggt ttttatggtc taaagaatcc aataggaata
    20521 tatatagaag gcttaaaatc tctgtaccct tatgaaaata ttggaatagg agctaatatt
    20581 agaggtttag ggttaataat gggaacagga tataattcgc ttgaaaagat tatggaatat
    20641 tcaggcctta caaatataga gttctataaa tttctccttc tatcaactgt tccaagtgtt
    20701 ttaaaattag
//
