LOCUS       NZ_LR027880.1          20878 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LR027880.1 Roseburia intestinalis L1-82 chromosome 1, complete
            sequence.
ACCESSION   NZ_LR027880
VERSION     NZ_LR027880.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:36:21
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2967501
            Orig. end    :: 2988379
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20878
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[2977501:2978379]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10878
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..20878
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20878
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="6"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(928..2679)
                     /locus_tag="ctg1_2742"
                     /transl_table=11
                     /translation="MRKQNSDFEARFISEEGSRLKNRDYFGYVELDEFACYVIADGITE
                     VTDVESARLAIETVILSFQENPSLSKRAVKRLLKRANRALLGKESDRRLKASITVVVTD
                     YQKMRYGYVGNTRLRMYRGGAVYRQTRDMSLAQEMVEQEKIAKDELMQHEERNNLYAYL
                     GQKNFKPVVSKKIKLAETDMIALYTRGIWENVDEAELDDVFAEADNEVQTTVDNIEDLL
                     LSRQPENLDNYTLAVIFVNKVYQNPEKRKRIKKIVMITFIVVIAAIVIGVVLWFLRDRK
                     VQRTEDMNYHFTNTVEYINTGNYVRAKEECEQAQKLAEKLKNSSMRNRLQEYSFVIETV
                     ILADESYSSADYEAAEEYYLSALDRTRYADNVGTDYIENKLENISVFLSVEDYINLGDS
                     LLEQGDYDGAEEKYLLAKKAALSVHDAEGKQTAMDSLEKLYEEKADAESAAQEEADSQA
                     QQTVAAAEMVAAGDKACLEKDYVGAKVYYTMAVAKYGEVADTAGQEDAQKKLDAVEEKL
                     SEQEEQKNTAAAYESQGEACRQSGDLWGAKSQYLSAKSIYQELGSDEDVQRIEEILSDI
                     DMQITEG"
     CDS             complement(2676..3506)
                     /locus_tag="ctg1_2743"
                     /transl_table=11
                     /translation="MSVPYLTVCILCAFLGIAFLYRFCLVFRSSREGYETGACKTIGSR
                     EIQMDYFTIEENENGLLAVLADGMGKEAGGRIAAKTVIRVFKEIFETYNMADHPSYFFK
                     KAFQTANREILKQMDEGRGMAAVSAVMIQGGFLFYGIVGNVKIAVFRNEELIPLGTGHT
                     VDVLAQDKYVEGILTREDALSMLQEKRIYNYLGKDGFKEIQFYDKPVRLQEGDVVAVFS
                     NGMQESVTWKEMEDCLARKKSCKRMAFDLVELVNQKKGDKDNASVILIRVGEMT"
     PFAM_domain     complement(2691..3335)
                     /aSDomain="SpoIIE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07228.14"
                     /description="Stage II sporulation protein E (SpoIIE)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2743_0110"
                     /evalue="1.10E-06"
                     /label="ctg1_2743"
                     /locus_tag="ctg1_2743"
                     /protein_end="272"
                     /protein_start="57"
                     /score="28.9"
                     /tool="antismash"
                     /translation="ENGLLAVLADGMGKEAGGRIAAKTVIRVFKEIFETYNMADHPSYF
                     FKKAFQTANREILKQMDEGRGMAAVSAVMIQGGFLFYGIVGNVKIAVFRNEELIPLGTG
                     HTVDVLAQDKYVEGILTREDALSMLQEKRIYNYLGKDGFKEIQFYDKPVRLQEGDVVAV
                     FSNGMQESVTWKEMEDCLARKKSCKRMAFDLVELVNQKKGDKDNASVILIRV"
     CDS             complement(3503..4009)
                     /locus_tag="ctg1_2744"
                     /transl_table=11
                     /translation="MSGNLIRCQNGHLFSSRRYGTVCPYCNIETATKEKKSVEKSQEEI
                     EDILFLEEENPVCGWIVCVKGPRRGKDYRVMDGKNFVGRADDMDIQILGDNKIARRNHA
                     VIVFDAKKRENMILPGDSNGLVYLNGEAVYLPQPLSAYDVIEMGESTFLFVPFCGEHYM
                     WEDDK"
     PFAM_domain     complement(3566..3766)
                     /aSDomain="FHA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00498.28"
                     /description="FHA domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2744_0111"
                     /evalue="2.80E-06"
                     /label="ctg1_2744"
                     /locus_tag="ctg1_2744"
                     /protein_end="148"
                     /protein_start="81"
                     /score="27.7"
                     /tool="antismash"
                     /translation="VGRADDMDIQILGDNKIARRNHAVIVFDAKKRENMILPGDSNGLV
                     YLNGEAVYLPQPLSAYDVIEMG"
     CDS             complement(4033..4569)
                     /locus_tag="ctg1_2745"
                     /transl_table=11
                     /translation="MNKKNFMDMMICSLSAAIIILCFTYMEQSRGRDTLMAVCGIVFLA
                     FLLLAVTDSLSGRQKKRGNGRGIQELLLLDEEGNEISAWHIGGKTSLLIGRDEHKENVD
                     INLQNTEYGGMADRQHAVLNYAAGQWYIEDLGSRNGVRIQDAKDGKVYQVSREHPCRIN
                     AGDIIFIGNTRLGAK"
     PFAM_domain     complement(4057..4293)
                     /aSDomain="FHA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00498.28"
                     /description="FHA domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2745_0112"
                     /evalue="1.30E-09"
                     /label="ctg1_2745"
                     /locus_tag="ctg1_2745"
                     /protein_end="171"
                     /protein_start="92"
                     /score="38.3"
                     /tool="antismash"
                     /translation="LIGRDEHKENVDINLQNTEYGGMADRQHAVLNYAAGQWYIEDLGS
                     RNGVRIQDAKDGKVYQVSREHPCRINAGDIIFIG"
     CDS             complement(4622..5065)
                     /locus_tag="ctg1_2746"
                     /transl_table=11
                     /translation="MNPYQVLGVSQTADEDTIKKAYRKAAKECHPDTHPGDKRAEERFK
                     EIGEAYRILSDKQKREEYNARAAQKEQKSAAGRNSAGTGRNGAGTGRKNTGGGTIDPGD
                     IEKEFERFFSMGKQSEKKENRTQQKINPMDVTDLFERYMGLKR"
     PFAM_domain     complement(4874..5062)
                     /aSDomain="DnaJ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00226.33"
                     /description="DnaJ domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2746_0113"
                     /evalue="3.90E-27"
                     /label="ctg1_2746"
                     /locus_tag="ctg1_2746"
                     /protein_end="64"
                     /protein_start="1"
                     /score="94.3"
                     /tool="antismash"
                     /translation="NPYQVLGVSQTADEDTIKKAYRKAAKECHPDTHPGDKRAEERFKE
                     IGEAYRILSDKQKREEYN"
     CDS             complement(5174..5599)
                     /locus_tag="ctg1_2747"
                     /transl_table=11
                     /translation="MSFLVKVEGSESFEVAKECVRSVKVTTDIPLDSNARTKDVGATMV
                     ITGKILAALDGDITDSTRKLALWSVVPAEKVDCYRKVTVEHVAGGVMERKYCFPNAFVL
                     DYKEEFGDVEGTGTFTLVLRQKKDKIASVAVEGNYSA"
     CDS             complement(5617..6045)
                     /locus_tag="ctg1_2748"
                     /transl_table=11
                     /translation="MGFRLAVSGGAENINLDEKTIQKVTFSSDSATDSNARATDFGIAV
                     KITGKMLYKVGADGEDGTLGLSKWSQVPSEQADCYRNAQIDVVSAGQVVRKYTIPNAFV
                     MEYEEHMDDETGVGTFYLHIKQKKDENDAVKIEGGYGE"
     CDS             complement(6080..8260)
                     /locus_tag="ctg1_2749"
                     /transl_table=11
                     /translation="VNTITQTNRTILFEEINPEKLNLLTLVGDVRGVNSVSDDKIKEIN
                     DALLVRSFDEFLEKFEPVVYSYFDANNQKVIYTLKKPETIEDELLSEIHLNRQNDYLKM
                     LMTLVEAKRAEGSINVDFKFEKLTDMISPKKVMDDIRQNRKELQYTYSEYAKLEDGDPK
                     KLDTADKLNLMFEEASVNYNNVMAMLPLAIEDIKTRLLLGDGQKKKDEAPLSIGVLSMD
                     EHGELKILEAPKENKKELMVLDDNANAGLIQAIEKDYMDLNEDGNEYVMSLVARTFCPL
                     ASTMESVVDIEKEVANYNSYLEFYKRSKDDFIKTVKPLVEKIMGVWAFFEQYPRNCKGM
                     KPSLVVSNVSNDMLAKSSNIPRLLAYLNTVNAKNDFENTIWYAIVPSVSLNSSSKLKAV
                     KERFKGNENVEKEDVNSMESLVRILDALKDYEVQCFFSYETGDKTTFNVMATEGIEKYE
                     TKCTQLIGKPFSEYAIPCIPNFTVIPKDKSGVILDNKMYITEQNTAALSKEKEDVMKIW
                     IDGVYIGAAYVAAGLVAAYQSPDYLKEVFKKNVDDELPGVRFDIESGDHALQVRTTMAK
                     EITGYTNDIKSDINRKNFGFVFSSENAVLKDMNIQNIMVYKARNLLTDGKSYEPIYKTQ
                     VTTYIQRVMRLATGDFKQENIVEFFSSKPTSQRSRWMEKKDCINAIIGNGDDIRYSIDE
                     AAGYCTLDIAFNGNVKNLEIEINRVNSEDRTF"
     CDS             complement(8272..10029)
                     /locus_tag="ctg1_2750"
                     /transl_table=11
                     /translation="MGKVEKITIKLAMLFIGLSLLFPARVLAAEKNEINEITEKKQIIF
                     LLDASKSMQGDGQWIEAADSACMIASALPKEYEVALLVYNTEIVYEEDFGNINQKTRHA
                     LETVELQGYTTPAVALETAADMFDSAAADKRVVFISDGEISLRDQSETETAIRQFENMV
                     DQIAEQGIKIDMFAIPNDKTENEVSYGTKVTSGEQYTVGENQTIEEITAKYLFQTLQIE
                     KIELGEAVSGEGNMTVDLQDTYMQNAKILLVSGENIEDFHVAGQCESLNMLQGNKFAVA
                     ELENPLERQITMDYSLENRGNVHTYLIKEYFLKADMEKSYTSEEGTFTLKVNVVNHQEK
                     PVLDSETLKDSISVLINGKEASYRVENGTAMVPYQTDETAKVNVEIAIQPSENVVHYIK
                     TADTVELTVPVVEEEPDYTVLWIVIISLCAVVLLLSVLYERKKQKKNDGETGSIIIEKS
                     EPPVLPKYDFSGQLAVYLLKGEQEEDVAPCSIKLFGKSRKSISFDWIKDRCGIDYKLSD
                     ADKIRFTGGKDHALCFKNSGYATIVKENQILKRERKYSLYYGEKILLIFNNGGTEIELH
                     YKNMKPSER"
     PFAM_domain     complement(9601..9903)
                     /aSDomain="VWA_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13519.8"
                     /description="von Willebrand factor type A domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2750_0114"
                     /evalue="1.60E-09"
                     /label="ctg1_2750"
                     /locus_tag="ctg1_2750"
                     /protein_end="143"
                     /protein_start="42"
                     /score="38.4"
                     /tool="antismash"
                     /translation="IIFLLDASKSMQGDGQWIEAADSACMIASALPKEYEVALLVYNTE
                     IVYEEDFGNINQKTRHALETVELQGYTTPAVALETAADMFDSAAADKRVVFISDGE"
     CDS             complement(10001..10600)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2751"
                     /sec_met_domain="AgrB (E-value: 2.4e-32, bitscore: 109.7,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKLFERIVDFMEENGSIQSEYRDIYLFALQTVAVYAFNIGTGVV
                     IGAAFGELLYCMIFLIAFMLLRQEAGGYHAPGWMSCYFLSCGILVLTLLWIKAEFAYQT
                     CLTIAAALAAGMGIFLFAPLEDKNKPLEEAEKKVIGKKARIIVVTELILGMVFLAVNQR
                     AAYAVLGAVIWCGVSYLAWSVKRYTEKNGKSREDNN"
     PFAM_domain     complement(10076..10585)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2751_0115"
                     /evalue="1.30E-31"
                     /label="ctg1_2751"
                     /locus_tag="ctg1_2751"
                     /protein_end="175"
                     /protein_start="5"
                     /score="109.5"
                     /tool="antismash"
                     /translation="ERIVDFMEENGSIQSEYRDIYLFALQTVAVYAFNIGTGVVIGAAF
                     GELLYCMIFLIAFMLLRQEAGGYHAPGWMSCYFLSCGILVLTLLWIKAEFAYQTCLTIA
                     AALAAGMGIFLFAPLEDKNKPLEEAEKKVIGKKARIIVVTELILGMVFLAVNQRAAYAV
                     LGAVIWC"
     CDS             complement(10597..10878)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2752"
                     /sec_met_domain="TIGR04223 (E-value: 7.1e-13, bitscore:
                     46.2, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRDRRLFFLHKNKKVTDNHTILDVLKILCQKMVLLGKKRGGIKMR
                     NLLNRYLSNLMTFGLEKVATGAATKCCYFILHQPKVPENLKKFSESKK"
     aSDomain        complement(10618..10725)
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2752_0034"
                     /evalue="7.80E-13"
                     /identifier="TIGR04223"
                     /label="ctg1_2752"
                     /locus_tag="ctg1_2752"
                     /protein_end="87"
                     /protein_start="51"
                     /score="46.2"
                     /tool="antismash"
                     /translation="LSNLMTFGLEKVATGAATKCCYFILHQPKVPENLKK"
     CDS             complement(10910..12205)
                     /locus_tag="ctg1_2753"
                     /transl_table=11
                     /translation="MMKVMLAAIEIFSLVYQRIFAQKVLTQRKHGRVWECFVWGMYFVI
                     SNFFTYSFAKSAWDNTGIFVVSFFFALRILYIDSAWVLSAVTAFMAISGALSEVLTYYG
                     WQIFVQKSGVKVDTANEDYLLLLVSKLVMFFFIKILLALIKRHKNIRLNTQEWVEIFMI
                     PGGSIVILAEMICQKESMSETLDFVAALMVMLINIFTYYLYDKIGETAEKRVREEVLQE
                     QSEYYLRQYNENMNLWVEMSEFRHNMTERYLMEKMYLEKGDYEALKKYCDNSLEKLHKQ
                     RKVSNTGCFYFDSIINYKAAVAETFDIKFETKLMIPRDLKVETEDICICLGNLLDNAIE
                     ASKKVKAEERSVCVEIRVDRRNLMMMVSNHYEEERKKSGNHYMTTKKEKHRHGFGLNII
                     RKIARRYDGEVIIDDGNHQFVVTVLLYEIFSM"
     PFAM_domain     complement(10931..11239)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2753_0116"
                     /evalue="8.40E-27"
                     /label="ctg1_2753"
                     /locus_tag="ctg1_2753"
                     /protein_end="425"
                     /protein_start="322"
                     /score="93.1"
                     /tool="antismash"
                     /translation="ETEDICICLGNLLDNAIEASKKVKAEERSVCVEIRVDRRNLMMMV
                     SNHYEEERKKSGNHYMTTKKEKHRHGFGLNIIRKIARRYDGEVIIDDGNHQFVVTVLL"
     CDS             complement(12206..12922)
                     /locus_tag="ctg1_2754"
                     /transl_table=11
                     /translation="MIRIGICDDLVEQLQIQEEMVRNIVCRLGLNTEIKCFQSGEDLLW
                     EMEQKGNMDIILLDIEMGGINGVETARRIREKDNRAILFFISYYEQYCKEIINVQPFRF
                     IDKPVSEEELDRGFREAFKAMSQKEEIFEYTYKKVPYKILVNKIRYFESDKRQVNLYST
                     DGVSSFYKKLDEVEAQLEQMNIKFLRISKSYLVNVNYVKEFRYEKVVMDDGKEFKIGPR
                     YKDKIRKSYIELMRIS"
     PFAM_domain     complement(12236..12502)
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2754_0118"
                     /evalue="3.10E-16"
                     /label="ctg1_2754"
                     /locus_tag="ctg1_2754"
                     /protein_end="229"
                     /protein_start="140"
                     /score="59.5"
                     /tool="antismash"
                     /translation="YKILVNKIRYFESDKRQVNLYSTDGVSSFYKKLDEVEAQLEQMNI
                     KFLRISKSYLVNVNYVKEFRYEKVVMDDGKEFKIGPRYKDKIRK"
     PFAM_domain     complement(12581..12892)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2754_0117"
                     /evalue="3.00E-13"
                     /label="ctg1_2754"
                     /locus_tag="ctg1_2754"
                     /protein_end="114"
                     /protein_start="10"
                     /score="50.0"
                     /tool="antismash"
                     /translation="VEQLQIQEEMVRNIVCRLGLNTEIKCFQSGEDLLWEMEQKGNMDI
                     ILLDIEMGGINGVETARRIREKDNRAILFFISYYEQYCKEIINVQPFRFIDKPVSEEEL
                     "
     CDS             complement(12947..13288)
                     /locus_tag="ctg1_2755"
                     /transl_table=11
                     /translation="MKLDYCAIGMRIKERRTKKEWSQEMLASTVGNSNPHMSNIEWGKT
                     KVSLATLIDIANALDTTLDALICDNLVKGKAVFDEEISQELEECSEEDIRIVYDMVKAL
                     VKSLAKRQH"
     PFAM_domain     complement(13094..13255)
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2755_0119"
                     /evalue="7.30E-10"
                     /label="ctg1_2755"
                     /locus_tag="ctg1_2755"
                     /protein_end="65"
                     /protein_start="11"
                     /score="38.9"
                     /tool="antismash"
                     /translation="IKERRTKKEWSQEMLASTVGNSNPHMSNIEWGKTKVSLATLIDIA
                     NALDTTLDA"
     CDS             complement(13538..14227)
                     /gene_functions="other (smcogs) SMCOG1157:hypothetical
                     protein (Score: 142.3; E-value: 3.4e-43)"
                     /gene_kind="other"
                     /locus_tag="ctg1_2756"
                     /transl_table=11
                     /translation="MGKVLGIVNRKGGVGKTTTATALSYLLSKEGCKVALIDFDGQRHT
                     TKLCGVTAPEQLSVTIYDILKCIVMNEELPDKGSYMIRTETGVDLIPANNKLDNFDKLM
                     CDTDFAEYKLKEFVDTIKEQYDYILIDGMPKMGTAMINVMICCDSLIIPVQSETLAVEE
                     MAEFLRAFHRIKSHANAETQQEKTKQCQRKQTDKKEICRTDTAYGRVDERDTFWGWTGE
                     EVSLIPP"
     PFAM_domain     complement(13685..14221)
                     /aSDomain="AAA_31"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13614.8"
                     /description="AAA domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2756_0120"
                     /evalue="3.20E-40"
                     /label="ctg1_2756"
                     /locus_tag="ctg1_2756"
                     /protein_end="181"
                     /protein_start="2"
                     /score="138.0"
                     /tool="antismash"
                     /translation="KVLGIVNRKGGVGKTTTATALSYLLSKEGCKVALIDFDGQRHTTK
                     LCGVTAPEQLSVTIYDILKCIVMNEELPDKGSYMIRTETGVDLIPANNKLDNFDKLMCD
                     TDFAEYKLKEFVDTIKEQYDYILIDGMPKMGTAMINVMICCDSLIIPVQSETLAVEEMA
                     EFLRAFHRIKSHANAE"
     CDS             complement(14639..16468)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 153.5; E-value: 1.8e-46)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2757"
                     /sec_met_domain="Peptidase_S8 (E-value: 9.4e-24, bitscore:
                     82.1, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNEKMENLLNLALDATEREREKSLDLDTGYDRAERTWEVIVKFG
                     GTEEALRGLFAEKFPEEYDRIRITNLRNEYAILLLPEHIVELVAALTEIEYMEKPKLLF
                     FAVNNGRRVSCINQLQTVGTEQGTLSSGRNLSGTGVIVAVIDSGIDYTHPDFRNADGTT
                     RILNLWDQTIPADSVADPFPAENGETSFLGAPSGYFLGTEFTRAVIDRALEQTTERERF
                     ALCPSRDISGHGTHVTGIAAGNGRASQGRYRGVAYESPLLIVKLGTPGERSFPRTTELM
                     QAVDYCIRKAQEYGMPIVINLSFGNNYGSHSGNSLLESYLDDMANYWRTSIVAGSGNEG
                     ASAVHASGTLRENITKDVEIAVSSYEPSLNLQIWKNYSDEIAVSLIHPNGTRVEPVRQI
                     LGPQRFRLGNTDILLYYGEPSPYSPYQEIYFDLLPVNEYIDSGVWTIQLVPQRIAAGNY
                     DMWLPAGGVLNEGTGFLMPSEETTLTIPSTAARVITVGAYDGYFDRAAAFSGRGYTRET
                     NQVKPDLVAPGVDITSCAPGGGYVTRSGTSMAAPFVTGGAALLMQWGIVDKNDPYLYGE
                     KMKAYLIKGARRLPAMRDYPNPVFGDNGIIVSS"
     PFAM_domain     complement(14702..15112)
                     /aSDomain="Peptidase_S8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00082.24"
                     /description="Subtilase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2757_0123"
                     /evalue="2.50E-17"
                     /label="ctg1_2757"
                     /locus_tag="ctg1_2757"
                     /protein_end="589"
                     /protein_start="452"
                     /score="63.1"
                     /tool="antismash"
                     /translation="IAAGNYDMWLPAGGVLNEGTGFLMPSEETTLTIPSTAARVITVGA
                     YDGYFDRAAAFSGRGYTRETNQVKPDLVAPGVDITSCAPGGGYVTRSGTSMAAPFVTGG
                     AALLMQWGIVDKNDPYLYGEKMKAYLIKGARRL"
     PFAM_domain     complement(15323..16060)
                     /aSDomain="Peptidase_S8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00082.24"
                     /description="Subtilase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2757_0122"
                     /evalue="1.90E-21"
                     /label="ctg1_2757"
                     /locus_tag="ctg1_2757"
                     /protein_end="382"
                     /protein_start="136"
                     /score="76.7"
                     /tool="antismash"
                     /translation="GTGVIVAVIDSGIDYTHPDFRNADGTTRILNLWDQTIPADSVADP
                     FPAENGETSFLGAPSGYFLGTEFTRAVIDRALEQTTERERFALCPSRDISGHGTHVTGI
                     AAGNGRASQGRYRGVAYESPLLIVKLGTPGERSFPRTTELMQAVDYCIRKAQEYGMPIV
                     INLSFGNNYGSHSGNSLLESYLDDMANYWRTSIVAGSGNEGASAVHASGTLRENITKDV
                     EIAVSSYEPSLNLQIWKNYSDEIA"
     PFAM_domain     complement(16166..16459)
                     /aSDomain="CspB_prodomain"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18425.3"
                     /description="Csp protease B prodomain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2757_0121"
                     /evalue="4.90E-30"
                     /label="ctg1_2757"
                     /locus_tag="ctg1_2757"
                     /protein_end="101"
                     /protein_start="3"
                     /score="103.5"
                     /tool="antismash"
                     /translation="EKMENLLNLALDATEREREKSLDLDTGYDRAERTWEVIVKFGGTE
                     EALRGLFAEKFPEEYDRIRITNLRNEYAILLLPEHIVELVAALTEIEYMEKPK"
     CDS             complement(16546..17244)
                     /locus_tag="ctg1_2758"
                     /transl_table=11
                     /translation="MWNRSELKSNAKLALKANYWKAVLVGLILSFILGSGSTAAQNSAR
                     SSTDGLTDIDPVMVFTVIGIILAAVFVAMVISILLSIFIWNPLEVGCQKFFINCKYGNA
                     ELGDIAYGFKNGYAHIGMIMFLRGLFTGLWMLLFIIPGIVKSYEYMMIPYLLAEHPEMT
                     RQEAFAESKQMMDGNKWDAFVLDLSFIGWTLLGVCTFGILLVFYVEPYIYLTRAELYHA
                     LKNNNKSVEF"
     PFAM_domain     complement(16567..16848)
                     /aSDomain="DUF975"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06161.13"
                     /description="Protein of unknown function (DUF975)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2758_0124"
                     /evalue="9.50E-25"
                     /label="ctg1_2758"
                     /locus_tag="ctg1_2758"
                     /protein_end="226"
                     /protein_start="132"
                     /score="87.9"
                     /tool="antismash"
                     /translation="LWMLLFIIPGIVKSYEYMMIPYLLAEHPEMTRQEAFAESKQMMDG
                     NKWDAFVLDLSFIGWTLLGVCTFGILLVFYVEPYIYLTRAELYHALKNN"
     CDS             complement(17346..19739)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:diguanylate cyclase (Score: 93.1; E-value:
                     4.3e-28)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2759"
                     /transl_table=11
                     /translation="LTLDSLYIGVPIGAFFCFLFIFFSFLNAGDAKPVRYFRQILLSCL
                     IWTGGVVMMRMQIMPGMRFWFHVSVFGFLTVPIFMYAFLFYMLEIKKNGFLTGYCIATV
                     VAMGINVVTEVFIPEPDIIRYADESIGYACHLSWGSYLFAAAEAVVIVYTTVLAHRAIG
                     NKFEKRKKLFPLLLGTVAILTGNLFVALPGNFFPYDMLGGIFMALCLLYIMWHKYLFDI
                     SNRIVIGCIYSVALAVSLLPVFNFNHNAEWYLGSVLPEIQQKVIVLVLGFTGWSLFVFY
                     LARKMAEGIMQRQNRKQIEVLRRFQNESASILRQEDLFKLLIGVVNEMFPVKDIFVFIK
                     NGEKFTVVKTAGGQMPDQAEQDEITAMLERSGAGECSEISLMKYDDEIQGFIYIKSEKR
                     TRLNYLERDYYWRIGVYAGVCLKNIRTYQEVYQISIHDELTGLYNRGYFKKFLAENWKE
                     EQKIALVYLDLDDFKLFNELYGEECGDRILKWCGHIIENTVGCQGNTFRFGSNEYVVLI
                     NSDEKKKVAQIAAKIQKNFLLADEEKPDVLQPVTASVGIAFYPDTASGADELLSQAERA
                     NFYAKRDGKNCIKIYGAHTEDELEDQQVQKHYEQIAPTIYALTAAIDAKDSYTFEHSCH
                     VSDYAVLLAKKIGLEPNDIEIAKEAGLLHDIGKIGIPESILKKQGRLNDEEYEIMKTHV
                     TNSIEMIHFLPNMNYVIPAVLSHHERYDGKGYPRGLKGEDIPLLGRILAVCDSFDAMTT
                     KRTYKEAMSIDYAISELEHNKGTQFDPKLAEAFIELLKEGKIEV"
     PFAM_domain     complement(17487..17855)
                     /aSDomain="HD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01966.24"
                     /description="HD domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2759_0127"
                     /evalue="1.10E-20"
                     /label="ctg1_2759"
                     /locus_tag="ctg1_2759"
                     /protein_end="751"
                     /protein_start="628"
                     /score="74.1"
                     /tool="antismash"
                     /translation="TFEHSCHVSDYAVLLAKKIGLEPNDIEIAKEAGLLHDIGKIGIPE
                     SILKKQGRLNDEEYEIMKTHVTNSIEMIHFLPNMNYVIPAVLSHHERYDGKGYPRGLKG
                     EDIPLLGRILAVCDSFDAM"
     aSDomain        complement(17583..17858)
                     /aSDomain="TIGR00277"
                     /aSTool="tigrfam"
                     /description="HDIG: HDIG domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2759_0036"
                     /evalue="1.40E-09"
                     /identifier="TIGR00277"
                     /label="ctg1_2759"
                     /locus_tag="ctg1_2759"
                     /protein_end="719"
                     /protein_start="627"
                     /score="35.7"
                     /tool="antismash"
                     /translation="YTFEHSCHVSDYAVLLAKKIGLEPNDIEIAKEAGLLHDIGKIGIP
                     ESILKKQGRLNDEEYEIMKTHVTNSIEMIHFLPNMNYVIPAVLSHHE"
     aSDomain        complement(17973..18443)
                     /aSDomain="TIGR00254"
                     /aSTool="tigrfam"
                     /description="GGDEF: diguanylate cyclase (GGDEF) domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2759_0035"
                     /evalue="1.90E-29"
                     /identifier="TIGR00254"
                     /label="ctg1_2759"
                     /locus_tag="ctg1_2759"
                     /protein_end="589"
                     /protein_start="432"
                     /score="100.4"
                     /tool="antismash"
                     /translation="ISIHDELTGLYNRGYFKKFLAENWKEEQKIALVYLDLDDFKLFNE
                     LYGEECGDRILKWCGHIIENTVGCQGNTFRFGSNEYVVLINSDEKKKVAQIAAKIQKNF
                     LLADEEKPDVLQPVTASVGIAFYPDTASGADELLSQAERANFYAKRDGKNCIK"
     PFAM_domain     complement(17982..18437)
                     /aSDomain="GGDEF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00990.23"
                     /description="Diguanylate cyclase, GGDEF domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2759_0126"
                     /evalue="3.50E-29"
                     /label="ctg1_2759"
                     /locus_tag="ctg1_2759"
                     /protein_end="586"
                     /protein_start="434"
                     /score="101.7"
                     /tool="antismash"
                     /translation="IHDELTGLYNRGYFKKFLAENWKEEQKIALVYLDLDDFKLFNELY
                     GEECGDRILKWCGHIIENTVGCQGNTFRFGSNEYVVLINSDEKKKVAQIAAKIQKNFLL
                     ADEEKPDVLQPVTASVGIAFYPDTASGADELLSQAERANFYAKRDGKN"
     PFAM_domain     complement(19074..19700)
                     /aSDomain="HisKA_7TM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16927.7"
                     /description="N-terminal 7TM region of histidine kinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2759_0125"
                     /evalue="3.30E-07"
                     /label="ctg1_2759"
                     /locus_tag="ctg1_2759"
                     /protein_end="222"
                     /protein_start="13"
                     /score="30.7"
                     /tool="antismash"
                     /translation="AFFCFLFIFFSFLNAGDAKPVRYFRQILLSCLIWTGGVVMMRMQI
                     MPGMRFWFHVSVFGFLTVPIFMYAFLFYMLEIKKNGFLTGYCIATVVAMGINVVTEVFI
                     PEPDIIRYADESIGYACHLSWGSYLFAAAEAVVIVYTTVLAHRAIGNKFEKRKKLFPLL
                     LGTVAILTGNLFVALPGNFFPYDMLGGIFMALCLLYIMWHKYLFDI"
ORIGIN
        1 tgtaattttg aaaaaaactg ctttttctgc tgttgcttaa catttcgcag gtatacccat
       61 gggaacttgt atctgtcttt tcaatgaaac ggtatacttc ccaatcccga aaagattctt
      121 tcagcgacgt cataataatt ttgtcttttt catgcctgac cttaagaaca tcctcattga
      181 tcccaagcat atatccgctg tccaaatcat agttttttaa atccagttca tgttcataat
      241 atttctcatc catacacggg accataaatt tacggcactg aaatgtgaac ttttctatat
      301 tccataacag cagcatatca tttttaatat cttcctcata gctgccaaaa tctattttca
      361 aaccgtttcc atccgtttcc ccgtccgtat ctatttcata aaatctatcc agatatcccg
      421 tattgactgt tgtccagcat atcttgttat agacgaatac ctgatacagc tccgacaacg
      481 cctgctgata acattttgct ttgcgcaccc ggacggtata ggatttgccg ctgtcatcga
      541 ccccttgaaa atctgctgct ttttcaaatt ctgctttctt ttgataactg cccgcaaaat
      601 agataatgca gggcattgct tcctgcttct cctgctcctt atcctcctgc agtaatgccg
      661 gaacaaccgg gtacagtgtt ccgttgatag ggtcataatc tttctgggtg ataaccgtca
      721 tagagactgc atatttctca tttggaatct ctatttcccg tttgatttga ttttccaaat
      781 ccagataccg tttttccatc agttcaaaaa tgggcacaag accttccaac aatatttccc
      841 ttgcatcctt ccgttcgcct aaatcctcta tttctgtcag cctttttcgt atgtgctgct
      901 gtaaatctgt aatactttcc acaatattta cccctctgtg atctgcatat caatatcact
      961 taaaatctcc tcaatcctct gcacatcttc atcgctcccc agttcctgat aaatcgattt
     1021 tgcagacaga tactgtgatt ttgctcccca caaatccccg gactgccggc aggcttctcc
     1081 ctggctttca taggcagccg ccgtattttt ctgttcctcc tgttcactta acttttcttc
     1141 tacggcatcc aattttttct gtgcatcttc ctgtcccgcc gtatccgcta cttcaccata
     1201 cttggcaact gccatcgtat aataaacttt cgccccaaca taatcttttt ccagacatgc
     1261 cttatctcct gctgccacca tctccgctgc ggcaactgtc tgctgtgcct gactgtctgc
     1321 ttcttcctgt gccgcgctct cggcatctgc cttttcctca taaagctttt ccagcgaatc
     1381 catagcagtc tgtttgccct ccgcatcatg tacggacaac gcggcttttt ttgccagcag
     1441 atacttctct tccgccccat cataatcgcc ctgctctaac agggaatctc caaggtttat
     1501 ataatcctcc accgacagga atacgctgat attctccagc ttattttcta tgtaatccgt
     1561 ccctacattg tccgcatatc tggtgcgatc caatgcagaa agatagtatt cttcggccgc
     1621 ttcataatct gcgctgctgt agctttcatc tgccagtatc acagtctcta tcacaaagga
     1681 atattcctgc agacggtttc tcatactgct gtttttcagc ttttctgcca gtttctgcgc
     1741 ctgctcgcat tcctcctttg ccctgacata atttccggta ttgatatatt ccaccgtatt
     1801 ggtaaaatga taattcatat cctcagtacg ctgcactttt ctatcacgca gaaaccacag
     1861 caccacaccg ataacgattg ccgctatgac aacaataaac gtaatcatca ctattttttt
     1921 tatccgtttc cgcttctctg gattttggta tactttattt acaaaaataa ctgccagcgt
     1981 atagttgtcc agattctccg gctgtcttga aagcagtaag tcctcgatat tatccaccgt
     2041 tgtctgcact tcgttgtcag cttctgcaaa gacatcatcc agttccgcct cgtccacatt
     2101 ctcccagatt ccccttgtat acagagcaat catgtcggtt tccgccagct ttatcttctt
     2161 tgaaaccacg ggcttaaaat ttttctgtcc cagataggca taaagattat tcctctcttc
     2221 atgctgcatc aactcatctt tggcaatttt ctcctgctcc accatctcct gggcaagaga
     2281 catatccctc gtctgacggt aaaccgcccc tccccggtac atgcggagcc ttgtgttccc
     2341 cacatatcca tatctcatct tctggtaatc cgttacaacc actgtaatag atgcctttaa
     2401 ccgtctgtca ctttcttttc ctaacaatgc ccggtttgcc cgctttaaca atctctttac
     2461 agcccgcttt gacagagatg gattttcctg aaaactaaga atgactgtct caatggcaag
     2521 ccttgcgctt tctacatccg tgacctccgt aattccgtct gcgatgacat agcaggcgaa
     2581 ctcatctaat tccacatacc caaaataatc tctgtttttt aacctgcttc cctcttcgga
     2641 aataaaccgt gcctcaaaat cactgttctg ttttctcatg tcatttctcc aactcttatc
     2701 agaattacgc tggcattatc cttatcgcct tttttctgat ttaccagttc caccaaatca
     2761 aatgccattc tcttacagct tttcttccgg gctaagcagt cttccatctc tttccatgtc
     2821 acgctctcct gcattccatt actgaaaact gccaccacat ccccttcctg taagcgaacc
     2881 ggcttgtcgt agaactgtat ttccttaaaa ccgtcttttc ccaggtaatt gtaaattctt
     2941 ttttcctgca gcatagacag ggcatcttct cttgtcagaa tgccttccac atacttatcc
     3001 tgtgccagca catctacggt gtgtcccgtt ccaaggggaa tcaattcctc atttcggaat
     3061 actgcaatct ttacattccc gacaatcccg taaaacagaa atcctccctg tatcataacg
     3121 gcgctgactg ccgccattcc tcttccctca tccatctgtt ttaaaatttc ccggtttgcc
     3181 gtctgaaacg ctttcttaaa aaaataggac gggtggtctg ccatgttgta cgtttcaaaa
     3241 atttctttaa aaacccgaat gactgtctta gcagcaattc tgccgcccgc ttcttttccc
     3301 attccgtctg ctaaaaccgc cagtaaacca ttctcatttt cttctattgt aaagtaatcc
     3361 atctgtattt cacggctgcc gatggtcttg caggctcccg tctcatatcc ctctctgctg
     3421 ctccggaata ccagacaaaa acggtacaaa aatgcaattc ctaagaaagc gcataagata
     3481 cagactgtca ggtacgggac actcatttat cgtcctccca catataatgc tccccgcaga
     3541 aaggaacaaa aaggaatgtg ctctccccca tctcaatcac gtcatatgcg cttaacggct
     3601 gcggcagata gaccgcttca ccgttcagat agaccagacc gttgctgtct cccggtaaaa
     3661 tcatgttctc ccgtttcttc gcatcaaata caatcaccgc atgatttctc cgtgcgattt
     3721 tgttatcccc cagaatctga atatccatat catctgcccg tcccacaaaa ttctttccgt
     3781 ccatgacccg gtaatctttg cctcttctcg gaccttttac gcatacaatc cagccgcaga
     3841 ccggattctc ctcctccaga aaaagaatgt cctcaatttc ttcctgcgat ttttccactg
     3901 actttttttc tttcgtggct gtctcaatat tgcagtacgg acacactgtt ccatatctcc
     3961 tgcttgaaaa aagatgtccg ttctgacagc gaattaaatt tccactcatg ttttttcctc
     4021 catatgtaca cgctattttg cccctaatct ggtattcccg ataaaaataa tatcgcctgc
     4081 gttaatccgg cagggatgct cccttgacac ctgatacact ttgccatcct tcgcatcctg
     4141 gattcttaca ccgtttctgc ttcctaaatc ttcaatatac cactgccccg ccgcataatt
     4201 taacacagcg tgctgacggt ctgccattcc gccatactct gtattctgaa gattaatgtc
     4261 cacgttttcc ttatgctcgt cccgtccgat taaaagggac gtctttccgc caatatgcca
     4321 ggctgatatt tcgtttccct cttcatctaa cagcaacagt tcctgtattc cccgcccatt
     4381 tcctcttttt ttctgtctgc cggacagaga atccgtcact gccagcagca aaaatgccag
     4441 aaatacaatc ccgcagacag ccataagcgt atcccgcccc ctgctctgct ccatatatgt
     4501 aaaacataga attataattg cagcggaaag actgcatatc atcatgtcca tgaaattttt
     4561 cttattcatt ttcacctcaa tatcaccgca aatctgcgtc tgaaaaatca aatcgtcttt
     4621 ctcaacgttt caatcccata taacgttcaa ataaatctgt cacatccatg ggattaatct
     4681 tttgttgcgt gcgattctcc tttttctcac tctgctttcc catggaaaaa aatcgttcaa
     4741 attccttttc aatatctccc ggatcaatcg ttcctcctcc ggtattcttt ctgcccgtcc
     4801 cagcaccgtt ccttcctgtc ccagcgctgt tccttcctgc cgcacttttc tgttctttct
     4861 gcgctgccct agcgttgtac tcttccctct tttgtttatc gctcagaatc cggtatgcct
     4921 ctccgatttc cttaaaccgt tcctctgccc gcttatctcc cggatgtgta tcggggtggc
     4981 attcttttgc cgcttttcta tatgcctttt ttatggtgtc ctcatcagcc gtttgcgaaa
     5041 cccctaatac ctgatatgga ttcatatttg ttccaacctt tcgttcatgg caatagaaag
     5101 cccgtaaaat gcgctttcta ttgccgattt aaggcgcagg ctgtcctatt tgctgacaat
     5161 ctgcgccctg ctgttatgct gaataatttc cttctaccgc tacagaagcg attttgtctt
     5221 tcttctgtct gagtactaat gtgaaggttc cggttccctc tacatcgcca aactcttctt
     5281 tgtagtcaag cacgaatgcg tttgggaaac aatattttct ctccattaca ccgcctgcca
     5341 catgctctac tgtcaccttc cgataacagt ccactttctc cgccggaaca acggaccata
     5401 atgccagctt cctggtactg tcagtaatat ccccgtccaa agccgctaaa atctttccgg
     5461 taattaccat agttgcgccg acatccttcg ttctcgcatt agaatccagc ggaatatcag
     5521 tagtaacctt tacgcttctg acacattcct tcgccacttc aaagctctcg cttccttcga
     5581 cttttactaa aaatgacata atttcctctc ctttctttat tcaccgtagc cgccttcgat
     5641 cttcaccgca tcattctcgt cctttttctg cttgatgtgg aggtaaaatg tacccacacc
     5701 ggtttcatca tccatatgct cctcatattc catgacaaac gcattgggga ttgtgtactt
     5761 tcttaccacc tgtcctgctg atacaacatc gatctgtgca tttctgtagc agtctgcctg
     5821 ctcggacgga acctgagacc atttggataa tccaagtgtt ccgtcttctc cgtctgctcc
     5881 caccttatac aacatttttc cggtaatctt tactgcaatg ccaaaatctg tagcccttgc
     5941 gttggaatct gttgcggaat cggaactgaa cgtaactttc tggatagttt tctcgtccag
     6001 attgatgttc tctgcgcctc cactcactgc taatctaaaa cccatgttcg tttcctcctt
     6061 cttttctttt agactttatt taaaatgttc tgtcctcgct gttgacccgg ttaatctcga
     6121 tttcgagatt cttcacgtta ccgttaaatg cgatatcaag cgtgcagtat cccgctgcct
     6181 cgtcgatgga ataccggata tcgtctccgt ttccgataat cgcattgatg caatccttct
     6241 tctccatcca tctgcttctc tggctggtag gcttgctgga gaaaaactcc acaatatttt
     6301 cctgcttaaa atcgcctgtc gctaaacgca tcactctctg aatgtaagta gtcacctgtg
     6361 tcttatagat tggctcataa ctctttccgt ctgtcagcag gttacgtgcc ttgtagacca
     6421 taatgttctg gatattcata tccttaagca ctgcattttc ggaagaaaat acaaatccga
     6481 aattcttccg gttgatatcg ctcttgatat cgttggtgta tcctgtaatc tcttttgcca
     6541 tggtagtccg aacctgcagt gcgtgatctc ctgactcaat gtcaaaccgg acacccggaa
     6601 gctcatcgtc cacgtttttc ttaaacactt cttttaagta gtccggactc tggtaagctg
     6661 ccaccaaacc ggctgccaca taagcagctc ctatgtagac accatcaatc cagattttca
     6721 taacatcttc tttttcttta gacagcgctg ccgtattctg ctctgtaatg tacattttgt
     6781 tatccagaat gacgccggac ttgtcttttg gtattacggt aaaattcggg atacagggaa
     6841 ttgcatattc actaaaaggc ttgccaatca actgcgtgca ttttgtttca tatttttcaa
     6901 ttccctctgt cgccataaca ttaaaggtgg tcttgtcccc cgtctcatag ctgaagaaac
     6961 actgcacttc ataatctttc agcgcatcca gaatccgaac cagcgattcc atgctgttca
     7021 catcctcttt ctctacgttc tcatttcctt taaaacgctc ctttaccgcc ttcagcttag
     7081 aactgctgtt taaggaaacc gacggaacaa tggcatacca gatggtattc tcaaaatcat
     7141 tttttgcgtt taccgtattg agatatgcta aaagtcgcgg aatgttgctg ctctttgcca
     7201 gcatatcgtt gctcacattc gataccacca gagaaggttt cattcccttg cagtttctcg
     7261 gatactgctc gaagaaagcc cataccccca tgattttttc caccaacggt tttactgtct
     7321 tgataaaatc atccttgctc cgcttgtaga actcaaggta agaattgtag ttcgctactt
     7381 ctttctcaat atctaccaca ctctccatcg tagatgccag cggacagaaa gttcttgcaa
     7441 ccaacgacat aacatactca tttccgtcct cgttcaaatc catatagtct ttctcgattg
     7501 cctgaatcag tccggcgttg gcattgtcgt ctaataccat cagctctttt ttgttttcct
     7561 tcggcgcctc taaaatctta agttctccgt gttcatccat actgagcacg ccaatgctta
     7621 acggcgcttc gtcttttttc ttctgtccat cgcccaacaa cagccttgtc ttgatatcct
     7681 ctatcgcaag cggcagcatt gccattacat tgttgtaatt gacacttgct tcttcaaaca
     7741 tcagattcag cttatctgcc gtatctaact tcttcggatc gccgtcctca agtttcgcat
     7801 attcactgta ggtatactga agttcttttc ggttctgtcg gatatcgtcc atgacctttt
     7861 tgggtgaaat catatccgtc agtttctcaa atttaaaatc tacgttgatg cttccctccg
     7921 cccgctttgc ctcaacaagc gtcatcagca ttttcagata atcattctgg cggttcagat
     7981 gaatttcact cagtaactca tcttcaatcg tttccggttt tttcagcgta tagattactt
     8041 tctgattgtt tgcgtcaaaa tacgaataca ccaccggctc aaatttctcc aaaaattcgt
     8101 caaaacttct caccagcaag gcatcgttta tttctttgat tttgtcgtca cttacgctgt
     8161 ttacccccct gacgtctcca acaagtgtca gaagattcag cttttccgga ttgatttcct
     8221 caaagagaat cgtcctgttt gtctgtgtta ttgtattcac tttgttcctc cttacctttc
     8281 gcttggtttc atatttttat aatgaagttc aatttctgtt cctccattat taaaaatcag
     8341 caatattttt tctccatagt ataaagaata ctttctctcc cgtttcaaaa tctggttttc
     8401 ttttacaatt gttgcataac cactgttttt gaaacacagt gcatggtctt ttccgccagt
     8461 aaacctgatt ttatctgcat ccgataattt atagtcaatc ccgcagcggt ctttgatcca
     8521 gtcaaaggat atactttttc gtgattttcc gaataactta atactgcagg gcgcaacgtc
     8581 ttcttcctgc tcccccttta acaaatatac cgccaactgt cccgagaaat catatttcgg
     8641 cagcacagga ggttccgatt tctctatgat aatggaaccc gtctcaccat cgtttttttt
     8701 ttgctttttc ctttcatata aaacagagag caaaagtacc actgcacata aagatataat
     8761 tacaatccaa agaaccgtat aatcaggttc ctcctctaca accggaactg tcaattccac
     8821 cgtatctgcc gtttttatgt aatgaaccac attttccgac ggctgaattg caatttccac
     8881 attcactttt gccgtctcgt ctgtctgata cggaaccatc gccgtgccat tttccacacg
     8941 gtaagacgct tccttgccat taatcaaaac agaaatactg tcttttaaag tttccgaatc
     9001 caaaaccggc ttctcctgat ggtttacaac atttaccttc agggtaaatg tcccttcctc
     9061 tgatgtatag gatttctcca tatcagcttt taaaaaatat tcttttatca gataagtatg
     9121 gacatttcct ctgttttcca gagaatagtc cattgtaatc tgccgttcca atggattttc
     9181 caattcagca accgcaaact tgtttccctg aagcatattc aggctctcac actgtcccgc
     9241 aacatgaaaa tcctcgatgt tttcccctga cacgagaagt atctttgcat tctgcatata
     9301 agtatcctgc agatccactg tcatatttcc ttctccggaa accgcctcgc caagttctat
     9361 tttttctatc tgtaacgtct ggaacagata ttttgcagtg atttcttcaa tcgtctggtt
     9421 ttcgcctact gtatactgct ctcctgacgt cactttcgtt ccatacgaaa cctcattctc
     9481 cgtcttatca ttggggattg caaacatgtc aatttttatt ccctgttctg caatctgatc
     9541 caccatattt tcaaactgcc tgattgcagt ttctgtttcg ctttgatccc gcagagaaat
     9601 ttccccgtcg gaaataaata ccactctttt atctgccgcc gcactgtcaa acatatcagc
     9661 cgccgtttcc aacgccaccg ctggggtggt gtagccctgc agttctaccg tctcgagtgc
     9721 atgtctggtt ttctgattaa tgtttccgaa atcttcctca taaacaattt ccgtgttata
     9781 taccagcaat gccacttcgt attctttcgg caacgccgac gctatcatac atgcactgtc
     9841 tgccgcctct atccattgtc catctccctg catggactta cttgcatcca acaaaaatat
     9901 aatctgcttt ttttcggtga tttcattgat ttcattcttc tccgctgcca aaacccttgc
     9961 cggaaacagc aaagaaagcc ctatgaacag cattgccaat ttaattgtta tcttctctac
    10021 ttttcccatt tttctccgta tatcttttta ctgaccatgc cagataactc actccacacc
    10081 agataactgc gcccaaaacc gcatatgcag ctctctgatt taccgctaag aataccattc
    10141 cgagtatcag ctctgttaca actatgattc gcgccttttt tccgattact ttcttttctg
    10201 cttcctccag aggcttattt ttatcctcca ggggagcaaa tagaaatatc cccatccctg
    10261 cagccaacgc cgcagcgatt gtaagacagg tctgataagc aaattctgct tttatccata
    10321 acaaggttaa aaccagaatc ccacatgaaa gaaaatagca gctcatccat cccggtgcgt
    10381 gatatcctcc tgcttcctgc cgcaacagca taaatgcaat cagaaatatc atgcaatata
    10441 acaattcccc aaaggccgcg ccaatgacaa cacccgttcc aatattgaaa gcatatacag
    10501 caacggtctg caacgcgaat agatatatat ccctgtactc cgattgaatg cttccatttt
    10561 cttccatgaa gtctacgatt ctttcaaaaa gttttctcat ttcttactct cagaaaactt
    10621 tttgagattt tccggcacct tgggctgatg cagaataaaa tagcagcatt ttgttgcagc
    10681 gcctgttgct actttctcca gaccaaatgt cattaaattg ctcaaatagc ggtttaacag
    10741 atttctcatc ttgattcccc ctctcttttt tcctaataat accatttttt gacacagaat
    10801 cttcaaaacg tcaagaatcg tatggttatc tgtaactttt ttatttttat gcaaaaaaaa
    10861 gagacgcctg tctctcactc acgcatctct tatttccctt tacatttctt tacatagaaa
    10921 aaatctcata caataatact gtcaccacaa attgatgatt cccatcatca atgataacct
    10981 ccccatcata ccgtctggct atcttcctta ttatattcag tccaaatcca tgcctgtgtt
    11041 tttctttttt tgttgtcata taatgatttc cgctcttttt ccgttcttct tcgtaatggt
    11101 tagaaaccat catcataagg tttcttctat ccactcgtat ttctacgcaa acactacgtt
    11161 cttctgcttt cacttttttg gatgcctcta tcgcattatc caacaaattt ccaagacaga
    11221 tacagatatc ttctgtttcc acttttaaat ctctcggtat catcagcttt gtttcaaatt
    11281 taatatcaaa tgtctcagca accgccgctt tatagttaat aatactgtca aaatagaaac
    11341 accctgtatt agatactttt ctctgcttat gtaacttttc taaagaatta tcgcaatatt
    11401 ttttgagtgc ctcatagtct cctttctcca gatacatttt ctccatcaga taccgttccg
    11461 tcatattatg gcggaactca ctcatttcta cccacagatt catgttttca ttgtactgtc
    11521 tgagataata ttcactttgc tcctgtaaaa cctcttcccg tactcttttt tctgctgttt
    11581 ctccaatttt atcatacaaa taatatgtaa aaatatttat cagcattacc ataagcgctg
    11641 ccacaaaatc caatgtctcg ctcatgcttt ccttttgaca gatcatttca gctaaaatga
    11701 caatgcttcc tccgggaatc ataaaaattt caacccattc ctgtgtattc aacctgatat
    11761 ttttatgccg cttgataagc gccagcaata tttttataaa gaaaaacata actagcttgg
    11821 aaaccagcaa tagtaagtaa tcctcatttg ccgtatctac tttgactcca cttttctgaa
    11881 caaatatctg ccatccataa taagtcaata cttctgataa tgctccgcta attgccataa
    11941 aagcagtaac tgccgataaa acccatgcag aatctatata taaaatacgt aaagcaaaaa
    12001 aaaatgagac aacaaatatt cctgtattgt cccacgcact ttttgcaaaa ctgtaagtaa
    12061 aaaaattaga aataacaaaa tacattcccc atacaaaaca ctcccacact ctgccatgct
    12121 ttctttgtgt caggactttt tgtgcaaaaa ttctctgata cactaaagaa aaaatttcaa
    12181 tggctgccag cattactttc atcatttagc ttatcctcat caattcaata taactttttc
    12241 gtattttatc cttatatctg ggacctattt taaattcttt gccgtcatcc atcactactt
    12301 tttcataccg aaattccttt acatagttca cattgaccag ataagattta ctaatcctta
    12361 aaaacttgat attcatctgt tctaactgtg cttctacttc atccagtttt ttataaaagg
    12421 aagaaacacc gtctgtactg taaagattca cctgtcgctt atcactctca aaataacgaa
    12481 ttttatttac caaaatctta tatggaactt ttttatatgt atactcaaaa atttcttctt
    12541 tttgactcat cgccttaaac gcttctctaa acccacgatc cagttcctcc tccgaaacag
    12601 gcttgtctat aaaccgaaat ggctgtacat taatgatttc cttacaatac tgttcatagt
    12661 aggaaatgaa gaacaaaatt gccctgttat ccttttcccg aatccgtctt gccgtttcaa
    12721 ctccgtttat cccgcccatt tcaatatcca aaagaatgat atccatattg cctttttgtt
    12781 ccatttccca tagcaaatct tctccgcttt gaaaacattt tatttctgta ttcagcccca
    12841 aacggcaaac gatattccta accatctctt cctgtatctg aagttgttct actaaatcat
    12901 cacaaatccc gatccttatc atatatcttt gcccccactg taacaactaa tgttgccgtt
    12961 ttgccagact cttaaccaaa gcttttacca tatcataaac aattctgatg tcttcttcac
    13021 tgcattcttc caattcctgt gaaatttctt catcaaaaac agctttccct ttcaccagat
    13081 tatcacaaat caatgcgtcc aatgtcgtat ccagagcgtt tgcaatatct atcaaagttg
    13141 ccaagcttac ttttgtcttt ccccactcta tattactcat atgtggatta gaatttccaa
    13201 cagtagatgc cagcatctcc tgcgaccatt ctttcttcgt ccgacgctct tttattctca
    13261 tacctattgc gcaatagtct aatttcattt ctatctccga aactcatttt cctttatcat
    13321 atcttttctt tgactattta agaatgcttt atatgctaat ttattttgct atggtttaat
    13381 aatctacaag aaatttttta ttttatttgc aaaattatca ttttaagctt aacatatacg
    13441 tcattttacg tttattacca atgtgtaacc agactatatt tctattttat cctaaatact
    13501 ttttttcact ttttagtctt ttagttaaaa tgaacgttca aggtggtatc aaactgacct
    13561 cctccccagt ccacccccaa aaggtgtctc tttcgtccac tcttccatac gctgtgtctg
    13621 ttctgcaaat ctccttttta tcagtctgtt tcctttgaca ttgcttagtt ttctcctgct
    13681 gcgtctctgc atttgcgtgg ctcttgattc tgtggaaagc tcttagaaac tctgccattt
    13741 cctctaccgc cagtgtttcc gactgtaccg gaataatcag actgtcacag catatcatca
    13801 cgtttatcat agctgtcccc atcttcggca taccgtcaat gaggatgtag tcatactgct
    13861 ccttaatggt gtccacaaac tctttcagct tgtattctgc aaaatcagta tcacacatca
    13921 gcttatcaaa gttatccagc ttgttattcg ctggaattaa atctactcct gtctctgtcc
    13981 ttatcatgta ggacccttta tccggcagtt cttcgttcat cacgatacac ttcaaaatgt
    14041 cataaattgt cacggaaagc tgctctggtg cggtcactcc gcaaagtttt gttgtgtgcc
    14101 tctgcccgtc aaagtcaatc aatgcgacct tacagccctc cttagacagc agatatgaca
    14161 gggctgtggc ggtcgtggtc ttacctactc cgccctttct gtttacaatt cctaaaacct
    14221 tgcccatacg tttgcttcct ttctcttgtt gaatttgtta ttttggttac attggattct
    14281 catgcaggca gcgagccaag gccaggcttg ctgaaccttg gcgactgcca tggtatcaat
    14341 ttcatatgac acttggataa aagtaggact gttcacttac ctccttccat gtaagaacac
    14401 tatcggttac aatttggaaa atagattttg cactaaaact gagattgatt agaaatggta
    14461 aatttgaaat acatttgaaa aatagatttt taactcctta tggtatttta gtgtcaagtt
    14521 atccgatttt cctttttcag aatgaaaacc aggttgtttt catcccaatt tgccgttttc
    14581 acagcaattt ctgttttgga cgaaatcagc ggaacccctt gattttactg gcttctcact
    14641 aacttgacac tataatacca ttatccccaa acaccggatt cggatagtcc cgcatcgccg
    14701 gaagccttct tgcccccttg atcagatacg ctttcatttt ttccccatac agatatggat
    14761 catttttatc cacgatcccc cattgcatca gaagtgctgc cccgccagtc acaaagggag
    14821 ccgccatcga tgttccgctt cttgtcacat acccgccgcc cggcgcacag gaagtaatat
    14881 ccacccccgg tgcgaccaga tctggtttga cctgattggt ctcccgcgta tacccgcgcc
    14941 cggaaaatgc cgccgcgcgg tcaaaatatc cgtcgtaggc tccgacggtg atcacccgcg
    15001 ccgccgtcga cggaatcgtc agtgttgtct cctccgacgg catcaaaaag cccgtacctt
    15061 cgtttaaaac accgcccgct ggaagccaca tatcataatt tccggctgca attctctgtg
    15121 gtacaagctg tatcgtccag acgccgctgt caatatactc gtttaccgga agcaggtcaa
    15181 aataaatttc ctgataagga ctgtagggac tcggttctcc gtaataaagc agaatatctg
    15241 tattccccag cctaaaacgc tgcggaccta aaatctgccg gactggttcc actctcgtac
    15301 cattcggatg aatcagcgag accgcaatct catcggaata atttttccaa atttgaagat
    15361 ttaaagacgg ctcataactg ctcacggcga tttccacatc tttcgtgata ttttcccgca
    15421 gggttccaga cgcatgcacc gccgacgccc cctcatttcc gctgccggca acaatcgacg
    15481 tccgccagta attcgccata tcatcaagat aactctctaa cagggagttg ccggagtggg
    15541 aaccatagtt attcccaaag ctcaaattta taacaatggg catcccgtat tcctgggctt
    15601 ttctgataca gtaatctact gcctgcatca gttccgtcgt tcttggaaaa gaccgttccc
    15661 ccggcgttcc caattttacg atcagaagcg gactttcata tgccactccg cggtatcttc
    15721 cctgtgaggc tctgccattt ccggctgcga tccccgtcac atgggtgcca tgcccggaga
    15781 tgtcacggct ggggcacaac gcaaaccgct ctctctccgt tgtctgctct aaagcgcggt
    15841 ctatcaccgc tctcgtaaat tcagttccaa gaaagtaccc tgacggtgcc cctaaaaatg
    15901 acgtttctcc attctccgca ggaaacggat ctgccacgct gtctgctggt atcgtctgat
    15961 cccacagatt taaaatccgg gtggttccgt ctgcattccg aaaatccggg tgtgtataat
    16021 cgatgccgga atcgatcact gccacgatca cgccggttcc acttaaattt ctgccagacg
    16081 acaatgttcc ctgctccgtc cccaccgtct gcagctgatt gatgcatgat acacgtctgc
    16141 cgttattcac tgcaaaaaac aaaagtttcg gtttctccat gtattcgatc tctgtcagtg
    16201 ccgccaccag ttccacaata tgctctggca aaagcaggat cgcatattca ttccgcagat
    16261 ttgtaatcct gatccggtca tactcctccg gaaatttttc tgcaaacagt cccctcaacg
    16321 cttcttccgt gcctccgaat tttacgataa cttcccaggt ccgttccgct ctgtcatacc
    16381 cggtatcgag atctaacgat ttttccctct cccgctctgt cgcatcgagt gcaagattta
    16441 acagattttc cattttctca ttggacataa aaatcccccg caaacgcact ccttacttat
    16501 tagaaatgca gcttgggggg attttatgac tcttttgggg taaatttaaa attctaccga
    16561 cttattatta ttttttaatg catgatacag ttctgcgcgt gtcagatata tgtaaggttc
    16621 tacataaaaa acaagaagaa taccaaatgt gcagacacct aacagcgtcc agccgataaa
    16681 tgaaagatct aacacaaatg catcccattt gtttccatcc atcatctgtt tactttctgc
    16741 aaaggcttcc tgtctggtca tctccggatg ctctgctaaa agatatggga tcatcatata
    16801 ctcataactt ttcacgatac ccggaatgat aaataataac atccagagtc ctgtaaacag
    16861 cccccgcagg aacatgatca tgccgatgtg cgcatatccg tttttaaatc cgtatgcaat
    16921 atcgcctaat tccgcgttac catacttaca gttaatgaaa aatttctgac atcccacttc
    16981 aagcggattc cagataaaaa tactgagcag gatgctgatc accatggcaa caaatactgc
    17041 tgccagtata atcccaatca cagtaaatac cattaccgga tctatatccg tcaatccatc
    17101 cgttgatgac cttgccgaat tttgggcagc tgttgagcct gaacctaaaa taaatgacag
    17161 aatcagtccc accagcactg ctttccagta attcgccttc aatgccagct ttgcattgct
    17221 ttttaactca cttctgttcc acatgttaaa ctcctcctga taaaaacatt ttacactttt
    17281 gcagtttaac acattaacgt ttttttgtca tccctcaaac aaaaattctc agaaaatctt
    17341 aagaattaga cctcaatttt cccttctttt aacaattcaa taaatgcctc tgccagtttt
    17401 ggatcaaact gtgttccctt attgtgttct aactcactga ttgcataatc gatcgacata
    17461 gcttccttgt aggtacgctt tgttgtcatc gcatcaaacg aatcacatac cgcaagaata
    17521 cgccctaaca gtggaatatc ttctcctttc aggcctctcg gatatccctt tccgtcatat
    17581 ctctcatgat gcgataatac agccggtatc acatagttca tattcggcag aaaatgaatc
    17641 atctcaatgg aattcgtgac atgtgttttc atgatctcat attcctcatc atttaacctg
    17701 ccctgttttt ttaagatact ctcaggaata ccaatctttc cgatatcgtg aagcagtcct
    17761 gcctcctttg caatttcaat gtcattcggc tcaagaccta ttttttttgc gagaagaacc
    17821 gcataatccg atacatggca ggaatgttca aaggtataag aatcctttgc atcgattgct
    17881 gcagtcagtg cgtaaatcgt tggtgcaatc tgttcataat gcttttgtac ctgctgatcc
    17941 tcaagttcat cttctgtatg tgctccataa attttaatac agttttttcc gtcccgtttt
    18001 gcataaaaat ttgcacgttc tgcctgactg agcagctcat ccgctcccga agccgtatcc
    18061 ggataaaatg caattccgac acttgcagtc accggttgta gaacatccgg tttttcttca
    18121 tccgcgagca gaaaattctt ctgtatcttc gccgcaatct gtgccacctt tttcttttca
    18181 tccgaattta tcagcaccac atattcattt gatccaaacc ggaacgtatt tccctgacat
    18241 cctacggtat tctctatgat atgtccgcac cattttaaga tacgatcccc acattcttcc
    18301 ccgtacagct cattaaaaag cttaaaatca tccagatcaa gatacaccag ggctatcttc
    18361 tgctcttctt tccagttctc cgccagaaac tttttaaaat atcccctgtt ataaagtcct
    18421 gtcagttcat catggatcga tatctgatat acttcctgat aagtacggat attcttaagg
    18481 cacacacccg catacacacc aattctccag tagtaatctc tctctaaata atttaatctg
    18541 gttcttttct ccgattttat atagataaat ccctgtatct catcatcata cttcatcaat
    18601 gaaatctcag agcactcacc tgcccccgat ctttccagca tagccgtgat ttcatcctgc
    18661 tctgcctgat ccggcatctg tccaccggct gtttttacaa ccgtaaactt ttctccattt
    18721 ttgataaaaa caaagatgtc ctttaccgga aacatctcat ttaccacacc aatcagcagc
    18781 ttaaacagat cttcctgccg caatatagac gccgactcat tctgaaaacg acgtaatacc
    18841 tcgatctgct ttctgttctg cctctgcatg attccctctg ccatttttct tgccagataa
    18901 aatacaaaca acgaccatcc tgtaaatcca agtacgagca ctataacttt ttgctgtatt
    18961 tccggcaata cactgccaag ataccactcc gcattgtgat taaaattgaa cacaggaaga
    19021 agactgaccg ccagtgcaac cgagtagata catccgatca cgatacggtt cgagatatca
    19081 aacagatact tgtgccacat gatatataac aggcacaatg ccataaaaat accgcccagc
    19141 atatcatacg ggaaaaaatt acccggcagt gcaacaaaaa gattgcctgt caaaattgca
    19201 actgttccaa gcagcagtgg aaataatttc tttcgttttt caaatttatt gccgattgcc
    19261 ctgtgcgcca aaactgtcgt atagacgatc acaactgcct ccgcagctgc aaataaataa
    19321 cttccccaag atagatgaca ggcatatcca atgctttcat ctgcataccg gataatatcc
    19381 ggttccggga taaatacttc tgtgacaaca ttgatcccca ttgccaccac agtagctatg
    19441 caatatccgg tcaggaaacc attctttttg atctccaaca tataaaataa aaatgcatac
    19501 ataaaaatcg gtaccgtcaa aaatccgaat accgacacat gaaaccagaa ccgcatcccc
    19561 ggcatgatct gcatacgcat cattactaca ccgccagtcc agatcagaca ggataaaaga
    19621 atctgtctga aatacctgac cggttttgca tccccggcat tcaggaatga aaaaaatata
    19681 aataaaaaac agaaaaacgc tccgattgga actccaatat ataaactatc cagcgtcaaa
    19741 gccgtttcct ccaaattgaa tgtaaaattt ttcaaaatca atcattatat tcatgtgcaa
    19801 aatcggcaca tgatccaatt cacaattcgt caatcataca agcatgttga ctctctctcg
    19861 ttcattatag catattttaa cctgcaattc catttttttc catcatccat catctttttg
    19921 atgggaatcc atcatctttt tgatggattt gcatacacta acagggatta aatctgtttt
    19981 ttaatggagt gaccttatgt gcggaattgc aggattttgc agcctgaaac gctgttatac
    20041 ggacagacag tccttttggg aaaatatact ggtgtccatg cacgaaaaac tcatccaccg
    20101 cggcggtgat gcttccggca tttatctgac acctcatgcc ggtctgtcac atcagagact
    20161 ttctatccgt gatatcacgc acggtgcaca gcctatgata cgtcaccggg acggggcaga
    20221 ttatgccatc gtctacaatg gggagatcta taataccgat gaactgatcc cggagcttac
    20281 tgctgccgga tataattttc tcacaacatc cgacacggaa gtgatcttat atgcctacat
    20341 gcatttcggt gcttcctttg tctcccgctt aaatggaatc ttttcctttg ccatctggga
    20401 cggtgccgca aaacagcttt ttctctaccg cgacagagta gggacaaagc cgctttttta
    20461 tcacgcaaaa gacggtgagc ttgtctttgc ctcagagcca aaagcactgt tctgctttcc
    20521 ggatctttca cccgctatta ccgaaaacag cctgagagaa ctgcttgcag tcgggccggc
    20581 gcgcaccccc ggatgtgggg tttttcagga tatctatgaa gttctacccg gacattacct
    20641 gtgttttgat gccatggggc tctccgatac cacctactgg gatctgaaat gtctgcccca
    20701 cacggactcc tacgaggaca ccgtggcaca tgtatctttt ctcatgcgcg ataccgtaaa
    20761 acggcagatg atttccgatg tgccggtctg taccttttta tccgggggca tcgattcaag
    20821 catcgtcaca gcccttgctg ccgcttacca gagggaacac ggtgaagtct taaatacg
//
