LOCUS       NZ_LR027880.1          21365 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LR027880.1 Roseburia intestinalis L1-82 chromosome 1, complete
            sequence.
ACCESSION   NZ_LR027880
VERSION     NZ_LR027880.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:36:21
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2637668
            Orig. end    :: 2659033
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..216)
                     /locus_tag="ctg1_2416"
                     /transl_table=11
                     /translation="MNNSKRIYRAAIYVRLSKEDGDLDDVRKAESNSISNQKSLILNYL
                     KDKEDIEIVSIREDDGYSGATFVEVR"
     protocluster    1..21365
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[2646166:2650015]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      8499..12347
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..21365
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21365
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="4"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(376..624)
                     /locus_tag="ctg1_2417"
                     /transl_table=11
                     /translation="MTVEQLDKISAQRLEDVDIDTLVEVNSIKYADGMPVEKKVAGMIA
                     KTGNPYFRRSGKSKIKISFSDNGESLKDNYIAMLANV"
     CDS             complement(702..1088)
                     /locus_tag="ctg1_2418"
                     /transl_table=11
                     /translation="MSEIRRGDIWMVDFGVPEDENDHKLHGIRPVVIVSNDSANRHSTV
                     FHAVPLTSKIHKKTYLPTHIFISSFKAVGLRTNSIAQCEQLCDVKDTDLIEKIGKVSKN
                     QLRQITKGMQIQLGMSTKHNNPIA"
     PFAM_domain     complement(744..1076)
                     /aSDomain="PemK_toxin"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02452.19"
                     /description="PemK-like, MazF-like toxin of type II
                     toxin-antitoxin system"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2418_0055"
                     /evalue="2.60E-22"
                     /label="ctg1_2418"
                     /locus_tag="ctg1_2418"
                     /protein_end="115"
                     /protein_start="4"
                     /score="79.4"
                     /tool="antismash"
                     /translation="RRGDIWMVDFGVPEDENDHKLHGIRPVVIVSNDSANRHSTVFHAV
                     PLTSKIHKKTYLPTHIFISSFKAVGLRTNSIAQCEQLCDVKDTDLIEKIGKVSKNQLRQ
                     ITKGMQI"
     CDS             complement(1081..1281)
                     /locus_tag="ctg1_2419"
                     /transl_table=11
                     /translation="MNLLSSHLRRTMPDKKELSIVTFSSETVVFDGKGDRVVACPTEQE
                     AVEYIRGQEIPVDRQGSEYYE"
     CDS             complement(1238..1558)
                     /locus_tag="ctg1_2420"
                     /transl_table=11
                     /translation="MSKCCVICVGRNADRAADRIEAYAKKADFEIVETIFKDTKSVERL
                     KFYIERDSIISILVSSIYDVSSDKDVVKGIMELAAEHGISINDESRGYEPALISFEEDN
                     AG"
     CDS             complement(1567..1989)
                     /locus_tag="ctg1_2421"
                     /transl_table=11
                     /translation="MNKAVIYFGATGNEAADQMVMQVLEEYCAVNGYEVVAVISENARP
                     EGMTFPMKFAFVGMAEVEDVDVVVTLMSDMVGDCEETIMDNIIMLGEHGITVETANDDM
                     AGYYQKMEQAGKKEDNGIVSLADFMAVFFKRLRADR"
     CDS             complement(2642..2965)
                     /locus_tag="ctg1_2422"
                     /transl_table=11
                     /translation="VYYDIVNSGERIKELRAARRMTRQQLAEQIGLSVDALRKIEAGVN
                     GAKIDTLISIAELFHITLDYLVCGCERKAEVDDLLVGLKEKEVQFIRNMVLNAVDNMKL
                     LTE"
     PFAM_domain     complement(2768..2932)
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2422_0056"
                     /evalue="2.00E-12"
                     /label="ctg1_2422"
                     /locus_tag="ctg1_2422"
                     /protein_end="66"
                     /protein_start="11"
                     /score="47.1"
                     /tool="antismash"
                     /translation="IKELRAARRMTRQQLAEQIGLSVDALRKIEAGVNGAKIDTLISIA
                     ELFHITLDYL"
     CDS             complement(3158..3370)
                     /locus_tag="ctg1_2423"
                     /transl_table=11
                     /translation="MIVYDRLWITLKKKNISQYALIKDYGIDKAQLQRLRKNMVVKTVI
                     LNRLCSILDCKIEDIMEFVPDEDIK"
     PFAM_domain     complement(3173..3355)
                     /aSDomain="HTH_26"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13443.8"
                     /description="Cro/C1-type HTH DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2423_0057"
                     /evalue="4.90E-17"
                     /label="ctg1_2423"
                     /locus_tag="ctg1_2423"
                     /protein_end="66"
                     /protein_start="5"
                     /score="62.2"
                     /tool="antismash"
                     /translation="RLWITLKKKNISQYALIKDYGIDKAQLQRLRKNMVVKTVILNRLC
                     SILDCKIEDIMEFVPD"
     CDS             3619..3852
                     /locus_tag="ctg1_2424"
                     /transl_table=11
                     /translation="MNDKNTYSVDKYLEIIAEKEGITKEEVQQEIGRAVSIALKSPDPK
                     MQRFWTDFPCENDTPTIEEIIYHLAEKFAKES"
     CDS             complement(3877..4221)
                     /locus_tag="ctg1_2425"
                     /transl_table=11
                     /translation="MGKREHIYEIIAENIRKERRRLGITQAELAERADVSLDTIKSVEN
                     GRRAMSLDTYLNIVHALESSPMVLMSQQHPEKHIERFAFMMNRCDEREIEFALHMIEQI
                     LRGQEDYLSE"
     PFAM_domain     complement(4024..4179)
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2425_0058"
                     /evalue="6.90E-10"
                     /label="ctg1_2425"
                     /locus_tag="ctg1_2425"
                     /protein_end="66"
                     /protein_start="14"
                     /score="38.9"
                     /tool="antismash"
                     /translation="IRKERRRLGITQAELAERADVSLDTIKSVENGRRAMSLDTYLNIV
                     HALESSP"
     CDS             complement(4482..5096)
                     /locus_tag="ctg1_2426"
                     /transl_table=11
                     /translation="MKKIISMVLSFILILGCSTTAFAAETHNYDTENLPHDGADYFETE
                     IKADEENEERISDFVTVYGYQYTKGSLKSGAWRNGTSGGSSTSSAKLSLNYTQDTSYNI
                     SFKASVSGGYTNGGTIGSELGVTLGASKSYSLGSGYSVTVPKGSHYLIKYRPMYYTYKV
                     VETKYKERYNEALGGMERYVVETKTCYVDVFSHWDFTHVAK"
     CDS             complement(5103..5366)
                     /locus_tag="ctg1_2427"
                     /transl_table=11
                     /translation="MKDFHLKILAIIMIIFGIFGLSTLPFLSIIVQYIDSITGFSSGNG
                     YLTNNMDYLFKSPLIYIGGFFVFSIILAIIYLVYSFFKAKRG"
     CDS             complement(5855..6541)
                     /locus_tag="ctg1_2428"
                     /transl_table=11
                     /translation="MVNMVNTAVNNNIYAGRKSGSKYNQSKAFQQKEVLETPDVAAVNK
                     YANVQEIYEALKCNVSCRGYEQGQDEIAEKEIQNDEPEISNDSSEKMTVWYQGVPLEEW
                     ALTDPKYTDSETGISWYIRDGKYPYMVGEDAEKFRKLCEESGEFALKKFAEMTGLIQKL
                     DDNTVAYVGDNGIAVKSKDGKEMFVDTSGLSYDIVMDMFRNLPRNGNFFSNKYWSDNIQ
                     KAQARS"
     CDS             complement(6681..7220)
                     /locus_tag="ctg1_2429"
                     /transl_table=11
                     /translation="MKKVKSLKALVLSLMLCLAMGTTAFASEVSTQGQAAPNANKAVEV
                     SDCGDLDVVPAYDDAVALADTIQYDANRTITRSNSRSGVFNGNYYYTINNSSVTKLCLN
                     VYMPNESGTDYLQGTITLVGNDGTSAPVQIANYSGDSWTLTFTGVKVGVRYHFHYELYS
                     VGSSQVGYIASAAYAQ"
     CDS             complement(7286..7813)
                     /locus_tag="ctg1_2430"
                     /transl_table=11
                     /translation="MRIGSGVQSVSELFGKRQNNSKTSVNGNEAFPQTSMKVYLKTDDM
                     LFSGGNGTGLSFYIKYAEESTDDNPVVIAKGIDENGKEFEEKININDIDLRNASYVEMS
                     ALEAYYDVDRGNSLSSFPQETGHMGLNERCDLISSFEKVIQDMNKLGKYDLQMFYMRNM
                     NTYLNLERQKKA"
     CDS             complement(7866..8354)
                     /locus_tag="ctg1_2431"
                     /transl_table=11
                     /translation="MLMGMGTMVSAAEKESSIPEYSETNDGGMTVNIAGDQEGTIVEGS
                     GNEEGINPLWWPGDGPAPQVTSISLYKYGWLTNGNFGVTIKVYGYGSDTTTFDGRSISW
                     IHQEPFIISGTGADGFYYTYDCGPITQAGSYRFNTTFRSTNFPNTTRSFSTVFTFSAN"
     CDS             complement(8499..8648)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2432"
                     /sec_met_domain="TIGR04223 (E-value: 1e-05, bitscore: 23.4,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVNKKVLKVVEHVMRNEAVYGIDRFPPACMGIFHQPKRPIIQK
                     KSER"
     aSDomain        complement(8526..8633)
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2432_0020"
                     /evalue="1.10E-05"
                     /identifier="TIGR04223"
                     /label="ctg1_2432"
                     /locus_tag="ctg1_2432"
                     /protein_end="41"
                     /protein_start="5"
                     /score="23.4"
                     /tool="antismash"
                     /translation="KKVLKVVEHVMRNEAVYGIDRFPPACMGIFHQPKRP"
     CDS             complement(8645..9226)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2433"
                     /sec_met_domain="AgrB (E-value: 2.5e-31, bitscore: 106.4,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEKIADDLIGQMTEARLIDKEMEARYVYVFICWIEKFITVGSII
                     VISLMFHKLLPTIFFLVFFLELRKRTGGYHLDKFYRCYLASIVSYLVIVIISEKLSEHP
                     QWLFAIVLLAITGIGLIGTANHPNMHMTSDELMESKKSARTIVLLEGCIILGCVLLDAD
                     MVYVSYMAIAVILCAALLCIAKIFKQEVKE"
     PFAM_domain     complement(8678..9211)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2433_0059"
                     /evalue="6.70E-30"
                     /label="ctg1_2433"
                     /locus_tag="ctg1_2433"
                     /protein_end="183"
                     /protein_start="5"
                     /score="103.9"
                     /tool="antismash"
                     /translation="ADDLIGQMTEARLIDKEMEARYVYVFICWIEKFITVGSIIVISLM
                     FHKLLPTIFFLVFFLELRKRTGGYHLDKFYRCYLASIVSYLVIVIISEKLSEHPQWLFA
                     IVLLAITGIGLIGTANHPNMHMTSDELMESKKSARTIVLLEGCIILGCVLLDADMVYVS
                     YMAIAVILCAALLCI"
     CDS             complement(9364..10668)
                     /locus_tag="ctg1_2434"
                     /transl_table=11
                     /translation="MLVNYIQSIMLTVLEIICCKIFFESFAEKRSENNWRNCSIILGTV
                     ICGYIIALLFYDQFVLKQMLAIVVIALFMSFYFKIHLKKAIILSLLFQALLLSVDYFTL
                     WINVSLFHSVAEINESHFVGGSLITVLAKIILFLVVLLIRKKIGGESSDVLRSTDWLRF
                     IFFPLFTIFTVIALIITSGSIENQKQENVFLVIALCLAGMNIVVFYMINDILKREIKIR
                     ENEVFQLKARNQTDMYRSISENFVKQRKKTHEYKNQIMCIESLIEMENYDELKDYVRSI
                     SGNLSTELDYIKTNNVIIDAILNSKYKETLDKGIVFIFQINDLSGIKMRDEDIVVILSN
                     LLNNAIEACEKCSGKKVMKMKLVKEKDNIIISVKNTYDGKLNIKDGEIQTSKKYEMDEH
                     GVGIKNIIEVITKYQGSYAIRNDNNEFYFSVILPN"
     PFAM_domain     complement(9370..9684)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2434_0060"
                     /evalue="4.70E-25"
                     /label="ctg1_2434"
                     /locus_tag="ctg1_2434"
                     /protein_end="433"
                     /protein_start="328"
                     /score="87.5"
                     /tool="antismash"
                     /translation="MRDEDIVVILSNLLNNAIEACEKCSGKKVMKMKLVKEKDNIIISV
                     KNTYDGKLNIKDGEIQTSKKYEMDEHGVGIKNIIEVITKYQGSYAIRNDNNEFYFSVIL
                     P"
     CDS             complement(10669..11427)
                     /locus_tag="ctg1_2435"
                     /transl_table=11
                     /translation="MSNLCVEGDEHMFRIAICDDERQFRKRIHDILIEYMNENDILYEI
                     DEFESGKDFISLGINLAKYDIVFLDVNMDELDGMETAQKIRKVSNDVFIVFVTAFITCA
                     PQGYSVGAIRYILKNNVNFPELIFECMDAISLNMNYVAQKKKFNFNEGTKIVALERLLY
                     IESRLHKLEFYIMEDKLKKYSIYGKLDELEKELQGNDFIRIHQSYLVNMKHIEKVSRYE
                     ALLNNGIKLEIPKARYKFVEETFVSYKGEI"
     PFAM_domain     complement(10705..10971)
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2435_0062"
                     /evalue="5.90E-16"
                     /label="ctg1_2435"
                     /locus_tag="ctg1_2435"
                     /protein_end="241"
                     /protein_start="152"
                     /score="58.6"
                     /tool="antismash"
                     /translation="TKIVALERLLYIESRLHKLEFYIMEDKLKKYSIYGKLDELEKELQ
                     GNDFIRIHQSYLVNMKHIEKVSRYEALLNNGIKLEIPKARYKFV"
     PFAM_domain     complement(11071..11385)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2435_0061"
                     /evalue="7.20E-16"
                     /label="ctg1_2435"
                     /locus_tag="ctg1_2435"
                     /protein_end="119"
                     /protein_start="14"
                     /score="58.4"
                     /tool="antismash"
                     /translation="IAICDDERQFRKRIHDILIEYMNENDILYEIDEFESGKDFISLGI
                     NLAKYDIVFLDVNMDELDGMETAQKIRKVSNDVFIVFVTAFITCAPQGYSVGAIRYILK
                     N"
     CDS             complement(11584..12168)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2436"
                     /sec_met_domain="AgrB (E-value: 7.2e-39, bitscore: 130.9,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAKFAKKINEILIQKGIVQKEDAELYRYGIENGIVVAGNLLASG
                     IFGIVTGRPGLVLVFLLFYASLRSYSGGSHCKSRIGCFLISMAILFIPVYTYEPVMKNV
                     PNAVILLIGVLAVVIIIVLAPVESINKPLDEEERRYYARVTHCITALQVCVLIILFCLD
                     LQDYFYAGYVSIVLIAVFMVMGKIAVKRYVQ"
     PFAM_domain     complement(11620..12153)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2436_0063"
                     /evalue="5.60E-38"
                     /label="ctg1_2436"
                     /locus_tag="ctg1_2436"
                     /protein_end="183"
                     /protein_start="5"
                     /score="130.2"
                     /tool="antismash"
                     /translation="AKKINEILIQKGIVQKEDAELYRYGIENGIVVAGNLLASGIFGIV
                     TGRPGLVLVFLLFYASLRSYSGGSHCKSRIGCFLISMAILFIPVYTYEPVMKNVPNAVI
                     LLIGVLAVVIIIVLAPVESINKPLDEEERRYYARVTHCITALQVCVLIILFCLDLQDYF
                     YAGYVSIVLIAVFMV"
     CDS             complement(12183..12347)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2437"
                     /sec_met_domain="TIGR04223 (E-value: 2.8e-10, bitscore:
                     38.0, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKLRKLMNRLSHGALTSVAALALTVTATNMNRCCWFIFGQEKLP
                     DNAKKLRKF"
     aSDomain        complement(12198..12305)
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2437_0021"
                     /evalue="3.10E-10"
                     /identifier="TIGR04223"
                     /label="ctg1_2437"
                     /locus_tag="ctg1_2437"
                     /protein_end="50"
                     /protein_start="14"
                     /score="38.0"
                     /tool="antismash"
                     /translation="ALTSVAALALTVTATNMNRCCWFIFGQEKLPDNAKK"
     CDS             complement(12451..13737)
                     /locus_tag="ctg1_2438"
                     /transl_table=11
                     /translation="MEYVIRFAISLFDLAVFMYYFHSNKKMKPVSKVWIWAGFTIAAII
                     WTFVSSIKNPYLNLATLLIVLILLSFYYESGMWTRIINIVTFMGIGMLFEPVALLLLHA
                     MNFHMGESYKYYFVMVICSFVRGNVMYILSKLISKKGMQIADFPKEILGVLVMVFAFTV
                     LNCCFVILLSLEAGSEKSLLMCASIVISIVLTDYFMLYMMERFNYLVQKQYEDAMYREE
                     MHYKDIYYEEAEKQNKEVQKLKHDMKHKLHELYHLLENSDGHELSEKIGAMCIEFEQID
                     EKQYSDNPIVDSVLRIKFGRAKARGIKVETSIRIPKQMQLDHGDIGVLYGNLVDNAVEA
                     CSKVPEGQRFVKIENKYQSGILLLVITNSKTGKKNKSLKTTKKDNIRHGHGVQSVRKVV
                     EKYNGTVSFTDKGDIFEVSAMLYGIEVKE"
     PFAM_domain     complement(12475..12768)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2438_0064"
                     /evalue="9.50E-23"
                     /label="ctg1_2438"
                     /locus_tag="ctg1_2438"
                     /protein_end="421"
                     /protein_start="323"
                     /score="80.1"
                     /tool="antismash"
                     /translation="GDIGVLYGNLVDNAVEACSKVPEGQRFVKIENKYQSGILLLVITN
                     SKTGKKNKSLKTTKKDNIRHGHGVQSVRKVVEKYNGTVSFTDKGDIFEVSAML"
     CDS             complement(13740..14447)
                     /locus_tag="ctg1_2439"
                     /transl_table=11
                     /translation="MLNIAVCDDSRTDVEMLESAFDKLAQYQFSYEVYFTAKELLKHVI
                     DYGEMYHLYIFDIEMPEMNGLQLAKEIRKIDAKALFVFLTGYTQYVMDVFEVITFDYIS
                     KPITVEKLESVLLKAMQYLHMIKRDFVFQFRKNQFRISCDDIVYFEKKGRHAVIHTISE
                     NFKANMTTEEIWKQLDDKVFAHIHVSYIINLGHIRAIDGDEVVMDNEERLLIARSHKQN
                     LKEKHMEFVRRMV"
     PFAM_domain     complement(13770..14036)
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2439_0066"
                     /evalue="2.40E-16"
                     /label="ctg1_2439"
                     /locus_tag="ctg1_2439"
                     /protein_end="226"
                     /protein_start="137"
                     /score="59.8"
                     /tool="antismash"
                     /translation="QFRISCDDIVYFEKKGRHAVIHTISENFKANMTTEEIWKQLDDKV
                     FAHIHVSYIINLGHIRAIDGDEVVMDNEERLLIARSHKQNLKEK"
     PFAM_domain     complement(14106..14438)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2439_0065"
                     /evalue="2.40E-14"
                     /label="ctg1_2439"
                     /locus_tag="ctg1_2439"
                     /protein_end="114"
                     /protein_start="3"
                     /score="53.5"
                     /tool="antismash"
                     /translation="IAVCDDSRTDVEMLESAFDKLAQYQFSYEVYFTAKELLKHVIDYG
                     EMYHLYIFDIEMPEMNGLQLAKEIRKIDAKALFVFLTGYTQYVMDVFEVITFDYISKPI
                     TVEKLES"
     CDS             complement(14492..14827)
                     /locus_tag="ctg1_2440"
                     /transl_table=11
                     /translation="LDTGRKDANIQIGKRLREARLNMNLEKSEIADVLGVTVEHYRKLE
                     AGVTGISVDKVLTLYHKYGIDPTYLITGESSNIKDFNLDYYVANSTKEQRNDFFDRVLA
                     YLSKLIR"
     PFAM_domain     complement(14606..14791)
                     /aSDomain="HTH_19"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12844.9"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2440_0067"
                     /evalue="1.70E-11"
                     /label="ctg1_2440"
                     /locus_tag="ctg1_2440"
                     /protein_end="74"
                     /protein_start="12"
                     /score="44.1"
                     /tool="antismash"
                     /translation="GKRLREARLNMNLEKSEIADVLGVTVEHYRKLEAGVTGISVDKVL
                     TLYHKYGIDPTYLITGE"
     CDS             complement(15046..15516)
                     /locus_tag="ctg1_2441"
                     /transl_table=11
                     /translation="MIKYLTMTIEKQKNIALIAHDGKKQDMLKWCMDNKEILQQHNLSG
                     TGTTARMIADHVGLKIKGYNSGPLGGDQQIGAKIVEGNIDMVIFFSDPLAAQPHDPDVK
                     ALLRIAQVYDIPIANNIATADFMIHSTLMNEQYSHQIENFKNTVDVRVKEMQ"
     aSDomain        complement(15064..15483)
                     /aSDomain="TIGR00160"
                     /aSTool="tigrfam"
                     /description="MGSA: methylglyoxal synthase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2441_0022"
                     /evalue="2.70E-56"
                     /identifier="TIGR00160"
                     /label="ctg1_2441"
                     /locus_tag="ctg1_2441"
                     /protein_end="151"
                     /protein_start="11"
                     /score="187.5"
                     /tool="antismash"
                     /translation="QKNIALIAHDGKKQDMLKWCMDNKEILQQHNLSGTGTTARMIADH
                     VGLKIKGYNSGPLGGDQQIGAKIVEGNIDMVIFFSDPLAAQPHDPDVKALLRIAQVYDI
                     PIANNIATADFMIHSTLMNEQYSHQIENFKNTVDVR"
     PFAM_domain     complement(15163..15438)
                     /aSDomain="MGS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02142.24"
                     /description="MGS-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2441_0068"
                     /evalue="4.20E-17"
                     /label="ctg1_2441"
                     /locus_tag="ctg1_2441"
                     /protein_end="118"
                     /protein_start="26"
                     /score="62.2"
                     /tool="antismash"
                     /translation="MLKWCMDNKEILQQHNLSGTGTTARMIADHVGLKIKGYNSGPLGG
                     DQQIGAKIVEGNIDMVIFFSDPLAAQPHDPDVKALLRIAQVYDIPIA"
     CDS             complement(15513..16334)
                     /gene_functions="regulatory (smcogs) SMCOG1260:AraC family
                     transcriptional regulator (Score: 61; E-value: 2.3e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2442"
                     /transl_table=11
                     /translation="VLLVYENRTDGIVVEWKKTVHFPPHLHEAIEVVYVTDGDIELGVG
                     QELYHMDEGDFAIVFPNVIHHYQVFGKKENKVIYLYLDPTLFPSYYKELQIYSPKNPVV
                     KKEQVHPDVVNAIKYLAGITEGNPMLIQAYVQMILAHVFAEMPMVDKSTVGSDDLIYNA
                     VEYVAKNFREKISLEKMAYDLCVSKYVLSRMFAKTFHCNFSKYVNGVRLNYAVAALENT
                     MDSITNICLDCGFESQRTFNRVFKDRYKITPREYRKRMEHNNRNGSLGVRR"
     PFAM_domain     complement(15558..15788)
                     /aSDomain="HTH_18"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12833.9"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2442_0070"
                     /evalue="3.40E-20"
                     /label="ctg1_2442"
                     /locus_tag="ctg1_2442"
                     /protein_end="259"
                     /protein_start="182"
                     /score="72.2"
                     /tool="antismash"
                     /translation="DLCVSKYVLSRMFAKTFHCNFSKYVNGVRLNYAVAALENTMDSIT
                     NICLDCGFESQRTFNRVFKDRYKITPREYRKR"
     PFAM_domain     complement(15939..16277)
                     /aSDomain="AraC_binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02311.21"
                     /description="AraC-like ligand binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2442_0069"
                     /evalue="2.10E-11"
                     /label="ctg1_2442"
                     /locus_tag="ctg1_2442"
                     /protein_end="132"
                     /protein_start="19"
                     /score="44.0"
                     /tool="antismash"
                     /translation="VHFPPHLHEAIEVVYVTDGDIELGVGQELYHMDEGDFAIVFPNVI
                     HHYQVFGKKENKVIYLYLDPTLFPSYYKELQIYSPKNPVVKKEQVHPDVVNAIKYLAGI
                     TEGNPMLIQ"
     CDS             complement(16359..17312)
                     /locus_tag="ctg1_2443"
                     /transl_table=11
                     /translation="MAYTDKNKLRVVYGDYTLGVHGDGFDYIFSYSQGGLESIVKNGYE
                     WLYRCPKPTFWRALTDNDRGSRFHIKSGSWLASDMFIDCKKTEVIMDGELQKQYAPDNN
                     SYGGDVAAGEIIVKYTYETVSNPVTTVIVSYTIDVTGNIKVDVDYTGVKGLPELPVFGM
                     RFIMPTLADKYMYKGLSGETYPDRKAGAEKGIYEVSDLSLTPYLVPQECGMRMDTEWLE
                     ITRHTSLDNSRTDSSPQTLRIEENDKAFAFSCLPYTASEIENATHHEELPPARRTVLCV
                     YGAVRGVGGIDSWGSDVEDDYRISAEKDIHYSFIIR"
     PFAM_domain     complement(16365..17249)
                     /aSDomain="Bgal_small_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02929.19"
                     /description="Beta galactosidase small chain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2443_0071"
                     /evalue="1.40E-61"
                     /label="ctg1_2443"
                     /locus_tag="ctg1_2443"
                     /protein_end="316"
                     /protein_start="21"
                     /score="208.4"
                     /tool="antismash"
                     /translation="GDGFDYIFSYSQGGLESIVKNGYEWLYRCPKPTFWRALTDNDRGS
                     RFHIKSGSWLASDMFIDCKKTEVIMDGELQKQYAPDNNSYGGDVAAGEIIVKYTYETVS
                     NPVTTVIVSYTIDVTGNIKVDVDYTGVKGLPELPVFGMRFIMPTLADKYMYKGLSGETY
                     PDRKAGAEKGIYEVSDLSLTPYLVPQECGMRMDTEWLEITRHTSLDNSRTDSSPQTLRI
                     EENDKAFAFSCLPYTASEIENATHHEELPPARRTVLCVYGAVRGVGGIDSWGSDVEDDY
                     RISAEKDIHYSFII"
     CDS             complement(17296..19197)
                     /locus_tag="ctg1_2444"
                     /transl_table=11
                     /translation="MNADMKWLDNPEVFRVNQLDAHSDHCYYMDYADMEKSENPLMQSL
                     NGQWEFAFSKNVMDRPENFYEENFDASSFDKIMVPGHIELAGYDKIRYINTMYPWEGKE
                     YHRGAYSMESTGDEAGMFSEAEYNPVGSYIKRFDLSEQMREKKIRICFEGVEEAMYLWL
                     NGQFVGYAEDSFTPSEFDLTPFIREKGNVLAVQVHKMSTAAFLEDQDFFRFFGIFRNVT
                     LKAVPEVHLEDVWFQPTLNKDNISGRVSVKMKVSAPEGKKVSAHLVLKDRENNQVAEDN
                     ITLEEKAGSLVGVIDTEVGSVKAWDNYCPYLYHAYVELRGEDGEILEIIPYDIGFRRLE
                     MIDKVIYLNGKRLVITGVNRHEWSAKTGRSISMDEMTADIDCMIRNNINAVRTCHYPDQ
                     IPWYYLCDKAGIYVMAETNMESHGTFQKLGAIEPSCSVPCSIPQWREAVVDRARSNFET
                     FKNHTAILFWSLGNESYAGDDIEAMNTYFKEKQDGRFVHYESSFYDRNYEETISDVESR
                     MYAKPYEVEEYLNNNPKKPYLLCEYMHDMGNSMGGLGTYMKLIDKYEMYHGGFIWDFID
                     QALLVKDEVTGKEVLRYGGDFDDKPSDYEFSGNGIVFADRKEKPAMQEVRYYYGLYR"
     PFAM_domain     complement(17308..18180)
                     /aSDomain="Glyco_hydro_2_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02836.19"
                     /description="Glycosyl hydrolases family 2, TIM barrel
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2444_0074"
                     /evalue="6.60E-110"
                     /label="ctg1_2444"
                     /locus_tag="ctg1_2444"
                     /protein_end="630"
                     /protein_start="339"
                     /score="367.1"
                     /tool="antismash"
                     /translation="EMIDKVIYLNGKRLVITGVNRHEWSAKTGRSISMDEMTADIDCMI
                     RNNINAVRTCHYPDQIPWYYLCDKAGIYVMAETNMESHGTFQKLGAIEPSCSVPCSIPQ
                     WREAVVDRARSNFETFKNHTAILFWSLGNESYAGDDIEAMNTYFKEKQDGRFVHYESSF
                     YDRNYEETISDVESRMYAKPYEVEEYLNNNPKKPYLLCEYMHDMGNSMGGLGTYMKLID
                     KYEMYHGGFIWDFIDQALLVKDEVTGKEVLRYGGDFDDKPSDYEFSGNGIVFADRKEKP
                     AMQEVRYYYG"
     PFAM_domain     complement(18187..18513)
                     /aSDomain="Glyco_hydro_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00703.23"
                     /description="Glycosyl hydrolases family 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2444_0073"
                     /evalue="3.00E-11"
                     /label="ctg1_2444"
                     /locus_tag="ctg1_2444"
                     /protein_end="337"
                     /protein_start="228"
                     /score="44.1"
                     /tool="antismash"
                     /translation="VHLEDVWFQPTLNKDNISGRVSVKMKVSAPEGKKVSAHLVLKDRE
                     NNQVAEDNITLEEKAGSLVGVIDTEVGSVKAWDNYCPYLYHAYVELRGEDGEILEIIPY
                     DIGFR"
     PFAM_domain     complement(18517..19074)
                     /aSDomain="Glyco_hydro_2_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02837.20"
                     /description="Glycosyl hydrolases family 2, sugar binding
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2444_0072"
                     /evalue="4.90E-30"
                     /label="ctg1_2444"
                     /locus_tag="ctg1_2444"
                     /protein_end="227"
                     /protein_start="41"
                     /score="104.7"
                     /tool="antismash"
                     /translation="MQSLNGQWEFAFSKNVMDRPENFYEENFDASSFDKIMVPGHIELA
                     GYDKIRYINTMYPWEGKEYHRGAYSMESTGDEAGMFSEAEYNPVGSYIKRFDLSEQMRE
                     KKIRICFEGVEEAMYLWLNGQFVGYAEDSFTPSEFDLTPFIREKGNVLAVQVHKMSTAA
                     FLEDQDFFRFFGIFRNVTLKAVP"
     CDS             complement(19264..20154)
                     /locus_tag="ctg1_2445"
                     /transl_table=11
                     /translation="LNLVIQSVTVGAVEMFGGGAAAWRTIAFIYCIIGIITNTLAVFSV
                     KELSDEELKDDSVAGEEDDKLSFKQTIKLLFSNKYFSMICVIYILQQLRASMVNVGIFF
                     MTYVLLNKNLFGVFSWANNIPLIIALAVTPALVSKMKGMYKLNKYSYMLATVCRLMVAV
                     AGYLGSVPLMLLFTVLTSLGEGPWQGDMSAVIAQCSEHTYLKSGKRIDGSMFSCTSLGV
                     KLGGGIGVALSGWLLDISGYINLDNAVQPDSCINMMYFMYLWLPFIFDIIITVILSFLN
                     VESANMKLKENMQNQ"
     PFAM_domain     complement(19309..20139)
                     /aSDomain="MFS_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13347.8"
                     /description="MFS/sugar transport protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2445_0075"
                     /evalue="1.60E-28"
                     /label="ctg1_2445"
                     /locus_tag="ctg1_2445"
                     /protein_end="282"
                     /protein_start="5"
                     /score="99.5"
                     /tool="antismash"
                     /translation="QSVTVGAVEMFGGGAAAWRTIAFIYCIIGIITNTLAVFSVKELSD
                     EELKDDSVAGEEDDKLSFKQTIKLLFSNKYFSMICVIYILQQLRASMVNVGIFFMTYVL
                     LNKNLFGVFSWANNIPLIIALAVTPALVSKMKGMYKLNKYSYMLATVCRLMVAVAGYLG
                     SVPLMLLFTVLTSLGEGPWQGDMSAVIAQCSEHTYLKSGKRIDGSMFSCTSLGVKLGGG
                     IGVALSGWLLDISGYINLDNAVQPDSCINMMYFMYLWLPFIFDIIITVILSFLNV"
     CDS             complement(20940..21365)
                     /locus_tag="ctg1_2446"
                     /transl_table=11
                     /translation="MKKVFTFFLAMAIIFGISGCGKKEYIVFPFSASDVVKIETYYSNS
                     EADTKEKTLTEEADIDYLYTFFSELPVKDANSDSTNDGSTIKFVFDLSDGTNYELVYIG
                     IATKKGYLQSETSDFYYFTSSDIIGVWANLSKMRLDF"
ORIGIN
        1 ttatcttacc tcaacaaaag ttgcccctga atagccgtca tcctcacgga ttgatactat
       61 ttcaatatct tctttgtctt ttaaataatt aagtatcagg gatttctgat ttgagatact
      121 gttactttca gcttttctca catcatcaag atcgccatct tccttagata atctaacata
      181 gatggctgct ctgtaaattc ttttagaatt gttcatgtcc accactcctt cgattttcta
      241 agttagaagt cccaaatcaa gaggaatgga aacataaata tgaaattgat accctttcgg
      301 gttagatgtc cttatttgtc tgtaatgata tcacaaatcc atctgaattt ccacccctaa
      361 ttttggctga ctgctctata cattggcaag catagcaata taattgtctt tcaggctttc
      421 cccattatcg gaaaatgaaa tcttaatctt gctctttcct gacctgcgga aatacggatt
      481 acctgtcttt gcaatcattc ccgcaacctt cttttccaca ggcattccgt cagcgtactt
      541 tatgctgttt acttccacca atgtatcaat atccacatct tctaatctct gtgccgatat
      601 tttgtccaac tgttcaactg tcatcctatc cctccaatca aattaagccg ccagatatgc
      661 tgacggctat gtaacaccgg agctttcgcc ccggctggaa tttatgcaat tggattatta
      721 tgttttgtac tcatacccaa ctggatctgc ataccttttg ttatctgtct taactggttt
      781 ttgcttactt tcccgatttt ttctatcagg tccgtatctt tcacatcaca taactgctca
      841 cactgagcga tactgttcgt tcttaatcca acagccttaa acgaactgat aaaaatatgt
      901 gttggcagat atgtcttttt atgaatctta cttgtaagcg gtactgcatg gaataccgtg
      961 ctgtgtctgt ttgcactgtc attgctcaca atcactactg gtctgatacc gtgcagcttg
     1021 tggtcattct catcttccgg tactccaaaa tcaaccatcc agatatcgcc ccgtcttatt
     1081 tcactcataa tattcacttc cttgtctgtc aactggtatt tcctgcccac ggatatattc
     1141 gacagcttcc tgttccgtag gacaggcaac aactctgtct cctttcccat caaacaccac
     1201 ggtttctgat gaaaatgtca ctatgcttaa ttccttttta tccggcattg tcctcctcaa
     1261 atgagatgag agcaggttca tagcccctgc tctcgtcgtt aatgctgatc ccgtgctctg
     1321 ctgcaagttc catgatacct ttcaccacat ctttatccga tgagacatca tagatactgc
     1381 ttaccagaat actgataatg gaatctcttt cgatataaaa tttaagtctt tccacagact
     1441 tcgtatcttt aaagattgtt tctacaatct caaaatccgc tttcttcgca tatgcttcta
     1501 tcctgtctgc ggctctgtcg gcatttctgc ctacgcagat aacacaacac ttactcatag
     1561 agcctcctat ctgtcggctc tgagacgctt gaaaaatact gccataaaat cagcaagtga
     1621 aacaataccg ttatcttcct ttttccctgc ctgctccatc ttctgataat atccagccat
     1681 atcatcgttt gctgtctcaa ccgtaatgcc gtgctctccg agcataatga tgttatccat
     1741 aattgtttct tcacaatcgc ccaccatatc actcataaga gtaacaacca catcaacatc
     1801 ttctacttct gccataccga caaaggcaaa cttcatagga aatgtcattc cctccggtct
     1861 tgcgttctcc gaaatgactg caaccacctc atatccattc acagcgcaat actcctcaag
     1921 aacctgcatt accatctgat ccgctgcctc atttcctgtt gctccaaaat atataactgc
     1981 tttattcatt ttaaaatctc cattcctgtt tttattttga tttgatatcc tgtgcacact
     2041 ttatctcctc acataaactg acctgccaat gctctctgta cttataagcc ccgttgttgt
     2101 ctgctggtta ctgcaaatca gtttgtgtgg gaagataaaa tactatcttc ccggtttctt
     2161 aaccatcccc gtatcgggta acatatcctt tgccagccac aatcacttcg tagtttcctg
     2221 cccatctgga cttacgaaag tagccactct ctgaaaatgc gttttgctga aattcaggtg
     2281 cacttattat ctcattacct ccggctgcta acccggtagg cacaaccctc tgctcttatc
     2341 cttaaaggct cctgctgtta cgtttctcat aatcggctac agctctgagg atagtcatcg
     2401 cacgaaatgg gattctgcca ccctgtcata gacaaggcga tataagctcg tgggatatgc
     2461 gtgtcctatt ctgttttcaa tattcaacgg ctcttttctc agaacctgaa caaagtataa
     2521 ctgacaccac gcatcttcta cagtaaccga cactcttttg aactaagagt aacactccca
     2581 cctgttccaa atccttataa aaaaagccgg actgcattat caaaaatgca atccgacttt
     2641 tttattctgt cagaagtttc atattgtcaa cggcatttaa taccatattc cggataaact
     2701 gtacttcctt ctccttcaga ccaaccagca gatcatcgac ttctgccttt ctttcacacc
     2761 cacacacaag ataatccaac gttatatgaa acaattcagc aatactaatc agcgtatcta
     2821 tttttgctcc atttacacca gcttcaattt tccgcagagc atccactgac aatccaatct
     2881 gctcggcaag ctgctgtctt gtcattcttc ttgccgcacg caactctttt attctttctc
     2941 cactattaac aatatcgtag tacaccttcc actcttttcc ggcaccttat atatttgctt
     3001 aagctgtatt cattgtaccg taagcgaatc ttttgtaaga gtgactaaac cagctatttc
     3061 aggtggaata ttgtacacct taataccaag aatataaata tttgcggatt aaaaaagaga
     3121 tatttccaaa ctctcattac attttggaaa tatctcttta cttaatatcc tcatccggca
     3181 caaactccat gatgtcctct atcttacaat caagtatgga acataatctg ttaaggatta
     3241 ccgtttttac gaccatattc tttcgcaatc gctgtaactg tgctttatct attccataat
     3301 ctttaattag tgcatactgg ctaatatttt tcttcttgag tgtgatccat aacctgtcat
     3361 atactatcat tacaaagacc tcctccttgt attctacgca agagtgtcct ataatgatat
     3421 ggtgcgtgta tgcaccatac tgtatgtata tgatagaata gaaaatagcc ataatctgca
     3481 tagaaaacag ctctcaaggt tattatgtaa tatagaacgg attatctgtt ttacttttat
     3541 ggtattcaac cgggacaatt caagcacctg acaatttgac cgcaaatacc cttctcagaa
     3601 aggattcaca acaacactat gaatgataaa aacacatact ctgttgataa atatttggaa
     3661 atcattgccg aaaaagaagg aatcacaaaa gaagaagtcc aacaggaaat tgggcgggca
     3721 gtttccattg ctttaaaaag ccctgatcca aaaatgcaac gcttctggac agactttcca
     3781 tgtgaaaatg atactcccac cattgaagaa atcatatacc atctcgctga aaaatttgca
     3841 aaagagtcat agacaaagga caggataact acccgtctat tcactcagat aatcttcctg
     3901 tcctcttaat atttgttcaa tcatatgtaa tgcaaattct atttctcttt cgtcacatcg
     3961 attcatcata aatgcaaaac gctcaatgtg tttttctggg tgctgctggc tcatcaaaac
     4021 cataggcgat gactccaatg catgaacaat attcaaatat gtatcaagac tcattgccct
     4081 tctgccattt tcaacacttt tgatagtatc caatgataca tctgcccgtt ctgcaagctc
     4141 tgcctgtgta attccaagcc ttctgcgttc ttttctgata ttctctgcaa taatttcgta
     4201 tatgtgctct cttttcccca tagccccatc atcctttctg acttatcgca ttatatcaga
     4261 aattattatg ggttttagga aactgtaatc ctttgacatt ttcgtgtaat actttgcata
     4321 ttccttctaa acaccaatct acttttacac tgaaatttaa aatttcagca aaatgtatat
     4381 aacaacatga gaaaagcccg tggcagatcc acgagcttta tctccagttt gaagcatgga
     4441 tatagatagt tccctgcttt tatttagtgt aacatacacc tttacttagc tacatgtgta
     4501 aaatcccagt gcgaaaatac gtctacatag caggtttttg tttcaaccac atatctctcc
     4561 atgccgccta atgcttcatt atatctttct ttatattttg tctcaacgac cttatatgta
     4621 taatacatag gacgatattt gattaaataa tgagatcctt ttggaacagt tacggagtat
     4681 ccgctaccta aagaatatga ttttgatgca cctagtgtaa cacccaactc acttcctata
     4741 gttccaccat ttgtatatcc accggaaact gaagctttaa aggaaatatt ataagaagta
     4801 tcttgagtgt aattcaatga taattttgcg ctagatgtag aactaccacc actcgtgcca
     4861 tttctccatg caccactttt taaactacct ttggtatatt gataaccata tacggtaaca
     4921 aaatcagaaa tgcgttcttc attttcctca tcagctttaa tttccgtttc aaaataatca
     4981 gctccatcat gaggcaaatt ttcagtgtca tagttatgag tctccgcagc aaacgctgtt
     5041 gtcgagcacc ccaaaatcaa tataaaactt aaaaccatac taattatttt tttcattaga
     5101 agtcaccccc gctttgcttt aaaaaaacta taaaccagat aaataattgc caaaatgata
     5161 ctaaaaacaa aaaagccacc aatataaata agaggacttt taaaaagata atccatgtta
     5221 ttggtaagat atccatttcc tgaactaaat ccagttattg agtcaatata ttggacaata
     5281 atggaaagaa acggaagcgt acttaaacca aatatgccaa aaattatcat tattatagct
     5341 aaaatcttca aatgaaaatc tttcatcaaa atcaccccct attttaatat cattttgtcg
     5401 ttatatgcag atcattctat aagcatattc ataattatat ttacttctcc tttcctcagt
     5461 attcaatgtg ccatatagag caatctgttg tatattctaa gaatagcagg aatcaaagca
     5521 aaagaaaata tcctatgcag aaagtgacct gtttttgcag aaaatgacca acagaacaaa
     5581 aattactcag aaatcaagta aaaaacacag cattgatact atttcaaagc tacagttctg
     5641 ctctaaagaa tatattgaga gtacgctttc aacaatattt cctagtctaa aaacggtatt
     5701 agaagaattt tggtaaaaat ttagcaggca ataatttgaa tattattgcc tgccaaatta
     5761 atgatgaaat catatgattc ttctgtcaat cagaaccaat ctgctttctc ctatcggagt
     5821 ccaagcatac acactcttgc aatataacgt atcatcagct ccgagcctgt gctttctgta
     5881 tattgtctga ccaatactta ttgctgaaaa aattcccatt tctaggcaaa tttctgaaca
     5941 tatccataac aatatcatat gataagcctg atgtgtccac aaacatctct ttcccatctt
     6001 tagatttaac tgcaattccg ttatcaccca catacgctac tgtattgtca tctaatttct
     6061 gtattaatcc cgtcatttcc gcaaatttct ttagcgcaaa ctccccggat tcttcacaaa
     6121 gttttcggaa cttttctgca tcctcaccta ccatatacgg atattttcca tctctaatat
     6181 accatgaaat tcccgtttct gaatccgtgt atttaggatc agttaatgcc cactcttcca
     6241 aaggaacacc ctgataccat actgtcattt tttcactgga atcattgctt atttctggtt
     6301 catcattttg aatttctttc tcagcaattt catcctgccc ctgttcatat cctctacatg
     6361 acacgttaca ctttagtgcc tcataaattt cttgaacatt tgcatatttg ttaactgctg
     6421 caacatccgg tgtctctaac acttcctttt gttgaaaagc ctttgattgg ttatattttg
     6481 aacctgattt tcttcctgcg taaatattgt tatttacagc ggtatttacc atatttacca
     6541 tatttataat ccctccagca gcaatataat ctaattttct tattatagta tgttgcactt
     6601 tatgccagat tgctataaaa tgcaacatac aatgaaaata ttctgttgcg cttgcttaat
     6661 atcccatatt caagcagcta ttattgtgca taagcagcag aagcaatata gcctacctgc
     6721 gaagacccaa cagaatacaa ctcataatgg aaatggtatc taacgcctac cttaacacct
     6781 gtaaatgtca gtgtccatga atctcctgaa tagttagcaa tttgtaccgg tgcacttgtt
     6841 ccgtcatttc ctacaagagt aattgttccc tgaagataat ctgttccact ttcattaggc
     6901 atataaacat ttaagcacaa ctttgtaacg cttgagttat taatggtgta ataataattt
     6961 ccgttgaata caccgcttct ggaattgctt cttgtaatgg ttctatttgc atcatactga
     7021 atcgtatctg caagagcaac ggcgtcatca taagcaggta ctacgtccaa atcgccacaa
     7081 tcgcttactt ctactgcctt atttgcatta ggggcagcct gtccctgagt ggatacttca
     7141 cttgcaaacg cagttgttcc cattgccaaa cataacatca aactcaacac caacgccttt
     7201 aaacttttta ctttcttcat tttaaaatct cctttcaaat taacatcgta taaattttca
     7261 ttccaacagg aatctataaa caactttatg cttttttctg tctttccaga tttagataag
     7321 tattcatatt tcgcatataa aacatctgca aatcatactt tcctaatttg ttcatatcct
     7381 gaataacctt ttcaaagctg gatataaggt cacatctttc atttaatccc atgtgaccag
     7441 tttcttgtgg aaaagagctg agactattac ccctatcaac atcataatat gcctccaaag
     7501 cactcatttc gacataagaa gcatttctca aatcaatatc gttaatatta atcttttctt
     7561 caaattcttt tccattttca tcaatccctt tggctatcac tacaggatta tcatctgttg
     7621 actcttctgc atacttaata taaaacgaaa gaccggttcc atttccgcct gaaaacaaca
     7681 tatcatccgt ctttaaatac actttcattg atgtctgagg aaatgcctca tttccgttaa
     7741 cagatgtttt gctattgttt tgtcgctttc caaataattc agatacactc tgcactcccg
     7801 aaccaatacg catttaacca cctccattcg cattataata tgttatttat atgaattaac
     7861 atatattagt ttgcactaaa cgtgaatacc gttgaaaagg aacgtgtagt attagggaag
     7921 tttgttgacc tgaaagttgt attaaatcta taacttcccg cttgcgtaat cggaccacaa
     7981 tcatatgtat aatagaagcc atctgcgcct gtaccagata taataaatgg ctcctgatgt
     8041 atccacgaaa tacttcttcc atcaaatgtt gtagtatcgc tgccatatcc atataccttg
     8101 atcgtaacgc caaaatttcc atttgtaagc cagccatatt tataaagtga aatgcttgtc
     8161 acctgcggag ccggtccatc tccaggccac catagcggat taatcccttc ctcattacca
     8221 ctgccttcaa ctattgttcc ttcctgatct cctgcaatat tcaccgtcat tccaccatca
     8281 ttggtttcag aatattcagg aatactactc tccttttctg ctgctgacac cattgttccc
     8341 atacccatta acatagtcaa tgctaatgca aatgcaataa ctttcttaat ttttttaaca
     8401 tatcagtacc tcctttttat acttgtcatc ttggaataaa caattaagtt cctatagcat
     8461 ctatggctac agatataata gtaaaacacg ccagttaact atctttcact tttcttctgg
     8521 ataatcggac gtttcggctg atgaaatatt cccatgcatg caggtgggaa tctatctatt
     8581 ccatatacag cttcatttct catgacatgt tctacaacct tcaacacttt cttattaacc
     8641 ttcttcattc tttcacctcc tgtttaaaaa tttttgctat acacagcaaa gctgcacata
     8701 atataacagc tattgccata taactaacgt aaaccatatc tgcatctaac agaacacagc
     8761 caagtattat gcacccctca agtaaaacaa tagtcctcgc agattttttc gattccatca
     8821 attcatctga tgtcatgtgc atattaggat gattcgctgt accaatcaat cctatccctg
     8881 ttatagcaag tagtactatt gcaaataacc attgtggatg ttctgacaat ttttcactta
     8941 taatcacgat aactaaataa gaaacaatgg atgctaaata acatctataa aacttgtcca
     9001 gatgatatcc gccagttctc tttcttaatt ctaaaaaaaa cacaagaaaa aatatagttg
     9061 ggagcagctt gtgaaacatc aaactgatta cgataatact gccaacagta ataaatttct
     9121 ctatccaaca gataaaaaca taaacatatc ttgcttccat ctctttgtca attaaccttg
     9181 cttcagtcat ctgaccaatt aaatcatcag ctattttttc aatcatagtt atgcctcctg
     9241 ccaaattaag tataacttta tctgtttaca aaacaatatc cattgcagaa agtgaccttt
     9301 ttttgcagaa aatgacaaaa aaaagtgatt tgcttgcagc aaatcacttt tttaaggttc
     9361 atcttagttt ggcaatataa ctgagaagta gaactcatta ttatcatttc gtatagcata
     9421 agagccttga tattttgtta taacctcaat tatatttttt attccaaccc catgctcatc
     9481 catttcatat ttctttgagg tctgtatttc tccatcttta atattaagtt taccatcata
     9541 tgtattcttt acagatataa tgatgttgtc tttctcttta accagtttca ttttcataac
     9601 ttttttgcct gagcactttt cacaagcctc tattgcatta ttcaaaagat tcgataaaat
     9661 aacaacaata tcctcatcac gcattttaat tcctgataga tcattgattt gaaagataaa
     9721 tacaattcct ttatccaatg tttccttata tttgctattt aatatagcat cgataatcac
     9781 attatttgtt ttaatatagt ctaactctgt actcaaattt ccgcttatac ttctcacata
     9841 atcctttagt tcatcataat tttccatctc tatcaaagac tcaatgcaca taatctgatt
     9901 cttatattca tgtgtttttt tccgttgttt aacaaaattt tctgaaatag aacggtacat
     9961 gtctgtctga tttcgtgctt tcagttgaaa cacttcattt tcacgaatct taatttcacg
    10021 ttttaatata tcatttatca tatagaacac aactatattc atccctgcca gacacaatgc
    10081 tataaccaag aatacatttt cctgcttttg attctcaatg cttccagatg ttatgatcaa
    10141 tgcaataact gtgaagattg taaaaagtgg aaaaaagata aatcgaagcc aatctgtact
    10201 tcttaaaaca tccgaggact cccctcctat ttttttcctg ataagcagaa caactagaaa
    10261 aagaattatt tttgccaaaa ctgttattaa acttccacct acaaaatgtg actcattaat
    10321 ttctgctaca ctatgaaaga gagagacatt tatccaaagt gtaaaatagt ctacagaaag
    10381 cagtaatgct tgaaataata atgataagat tattgctttt tttaaatgga ttttaaaata
    10441 aaagctcata aacagcgcaa tgacaacaat agctaacatc tgctttagga caaactgatc
    10501 ataaaataac aaagctatta tatatccaca tattaccgtt cctaaaataa tactacagtt
    10561 tctccaatta ttttcggatc tcttttcagc aaaactttca aaaaatattt tgcagcatat
    10621 tatttccaat accgtcagca ttatactttg aatgtaatta accaacatct atatttctcc
    10681 tttatacgaa acaaatgttt cttcaacaaa tttatatcgt gcttttggaa tttctaattt
    10741 aataccattg ttcaataacg cctcataccg gctgactttc tcaatatgct tcatattaac
    10801 cagataactt tgatgtatcc ggataaaatc attaccttgc aactcttttt ccagctcatc
    10861 tagtttgcca tatattgaat atttttttaa cttgtcctcc ataatgtaaa attccagttt
    10921 atgcaatctg ctctctatgt ataataaacg ctctaatgct acaatctttg taccctcatt
    10981 aaagttaaat ttcttctttt gggctacata attcatattc aagctgattg catccataca
    11041 ctcaaatatt agttccggaa aatttacatt atttttcaaa atatatctta tagctcctac
    11101 gctgtatcct tgaggggcac atgtaataaa tgctgtaaca aaaactataa aaacatcatt
    11161 gctgactttt cttattttct gcgcagtttc cattccatcc agttcatcca tatttacatc
    11221 caaaaaaaca atatcatact ttgccagatt gatacctaaa cttataaaat cctttcctga
    11281 ttcaaattca tcaatttcgt ataatatatc attttcattc atatattcta ttaaaatatc
    11341 atgaatgcgt tttctaaatt gtctttcatc atcacatata gcaattctga acatatgctc
    11401 atccccttcc acacacaaat ttgacatact tctttcattt ggttggatta ttttttgtat
    11461 attttcctat tttttattat atttcggcat ctttatccaa aattttaacc actactctat
    11521 atttgtaata tcccatgttc gtctacaaaa ttatatatca atacctattt tttatacatt
    11581 ttgctattgc acatatcgtt tcactgcaat ctttcccata accataaata ctgctattag
    11641 gactatactc acatacccag cataaaaata atcttgcaga tccagacaaa acaaaattat
    11701 aagaacacat acctgtaatg ccgttatgca atgtgttacc cttgcataat accttctttc
    11761 ttcctcatca agcggtttat tgatactttc cactggggca aggacaataa taattaccac
    11821 tgcaagaact ccgatcaata aaatcacggc attaggaaca tttttcatta caggctcata
    11881 tgtataaacc ggaataaata aaattgccat tgatatcaaa aaacagccga ttctactctt
    11941 acagtggctg cccccactat agcttctcaa cgaggcataa aataacagga agaccagaac
    12001 aagtcccggt ctccccgtca caatgccaaa tattccagaa gccaaaaggt ttcctgcaac
    12061 aacaatgcca ttttctatcc catatcggta cagttctgca tcctcttttt gcacaatccc
    12121 cttttgtatc aatatttcat ttatcttctt tgcaaattta gcaatcatac cctgttacca
    12181 ccttaaaatt ttctaagttt tttcgcatta tccggtaact tttcctgtcc gaaaataaac
    12241 cagcagcaac ggttcatatt ggttgcagtt accgtaaggg caagtgctgc cacgctggtt
    12301 aatgctccat gactgagtcg gttcatcaat tttcttaatt ttgacatatg tatatgtcct
    12361 cctttacatt tgatgaatgc actatatcat actttatggg aaaatccggc aaagtgtaac
    12421 agattgacat ttaagtgtaa cgctttgcat ttattccttc acttcaattc catagagcat
    12481 tgctgaaacc tcaaatatat cccctttatc tgtaaaactg accgttccat tgtatttttc
    12541 taccacttta cgaacactct gaacaccatg cccatgtcgg atattatctt tcttggttgt
    12601 tttcaggctt ttatttttct ttcctgtttt gctgtttgtt attacaagaa gcaaaatccc
    12661 cgactggtac ttattttcaa tctttacaaa acgctgtccc tccggcacct tgctacaggc
    12721 ttctaccgca ttatccacaa gatttccata caatacacct atatccccgt gatcaagctg
    12781 catctgcttt ggaatacgaa tagatgtttc tacttttatt ccccttgcct ttgccctgcc
    12841 aaatttaata cggagcacag aatctacgat tggattatca gaatactgct tttcatctat
    12901 ctgctcaaat tctatgcaca tcgcaccgat tttctctgaa agttcatgcc catcactatt
    12961 ttccaacaga tgatacagtt catgcaattt atgtttcata tcgtgcttta acttctgcac
    13021 ttccttattc tgtttttctg cttcttcata atagatgtct ttatagtgca tttcttccct
    13081 gtacattgca tcctcatact gtttttgcac aagataatta aaacgttcca tcatatacag
    13141 cataaaataa tctgtcagga caatggaaat tacaatactg gcacacataa gcaggctttt
    13201 ttcactgcca gcttccaatg acaaaagaat aacaaagcag cagttcaaca ccgtaaaggc
    13261 aaataccata acaagcacac ccaaaatttc tttcggaaaa tcagcaatct gcatcccttt
    13321 ctttgaaatc aattttgaca gaatatacat cacatttcca cgaacaaagc tgcatattac
    13381 cattacaaaa taatatttat aactttctcc catatgaaaa ttcatagcat ggagtaacag
    13441 caaggctaca ggttcaaaca gcattccaat acccatgaat gtcacaatat ttataattct
    13501 cgtccacatt cctgattcat aataaaatga taacagtata agcacaatca aaagagtcgc
    13561 aagattcaga tacggatttt ttatgctact gacaaatgtc catataattg cagcaatggt
    13621 aaatccagcc catatccata cctttgatac tggtttcatt ttcttattgg aatgaaaata
    13681 atacataaac actgccagat caaacaggct gatggcaaag cgtatcacat attccatcct
    13741 taaaccatcc tccttacaaa ctccatatgt ttttctttta aattctgctt atgggagcgg
    13801 gcaatcagaa gtctttcttc attgtccatc actacttcat ctccatcaat cgccctgata
    13861 tgcccaagat tgatgatata tgatacatga atatgggcaa agaccttatc atcaagctgt
    13921 ttccatattt cttcagttgt catatttgcc ttgaaatttt ctgaaatcgt atgtatcact
    13981 gcatgacgac ctttcttctc aaaatacaca atatcatcgc agctaatacg aaactgattt
    14041 tttcggaact gaaagacaaa gtcacgcttt atcatatgaa gatactgcat ggcttttaaa
    14101 agaacggact ccagcttttc cactgtaatc ggtttagaaa tatagtcaaa ggtaataacc
    14161 tcaaaaacat ccataacata ctgcgtatat ccagtcagga atacaaacaa tgctttggca
    14221 tctattttcc ggatttcttt tgcaagctgc aaaccattca tctccggcat ttcaatgtca
    14281 aatatataca gatgatacat ttctccataa tctataacat gcttcagcaa ctccttcgct
    14341 gtaaaataca cttcataaga aaactggtac tgtgctaact tatcaaaagc actttccagc
    14401 atttctacat ctgttctgct gtcatcacag accgcaatat taagcataac acttcctcct
    14461 tttcgagctt ggaagcagga agcacttcaa tttatctaat caacttagat aaatacgcca
    14521 gcacacggtc aaaaaaatca tttctctgct cttttgtgct gttcgcaaca tagtaatcca
    14581 aattaaaatc ttttatgttg ctgctctcgc ctgttataag atatgtagga tcaattccat
    14641 atttatgata gagtgtcaat actttatcta cagatattcc agttacacct gcttcaagtt
    14701 ttcgataatg ttctactgta acacccaata catccgcaat ttctgacttt tcaaggttca
    14761 tattcagtct tgcctctctt agtctctttc ctatctgtat attggcatct tttcttcctg
    14821 tgtccaagat tttgcacctc ttttccatgt taatcatatc aatgggactt tgattctcat
    14881 agtccagaaa acaacccaat gcacatcatt ttatgctcgt gagtaggtta atttgtgctt
    14941 ttattaaaaa aacgaatggc acacctgatg ccattcgtct ttatctgctt tatattctgt
    15001 tgtaaattct attagcggac agcttttggc tatttatcat atccatcact gcatttcttt
    15061 tactctgaca tccactgtat ttttaaaatt ttcaatctga tgtgaatact gttcattcat
    15121 aagtgtggaa tgaatcataa aatccgctgt cgcaatatta tttgcaatcg gtatatcata
    15181 cacctgtgca attctaagaa gtgccttaac atctggatca tgtggctgtg ctgccagtgg
    15241 atcggagaag aaaataacca tgtcgatatt tccctctaca atttttgccc ctatctgctg
    15301 atctccacct aatggaccac tgttatatcc ttttatcttt aatcctacat gatctgctat
    15361 cattctcgca gtcgttccgg ttcctgacag attatgttgc tgtaaaattt ctttattgtc
    15421 catacaccat ttcaacatat cctgtttttt cccatcatga gcaatcaaag ctatgttttt
    15481 ttgtttttca atcgtcattg taagatattt aatcatctgc gtacccccaa gctgccgttt
    15541 ctattattgt gttccatcct ttttctgtac tctcttggtg taatcttgta tctatcctta
    15601 aaaacacggt taaaagttct ttgactttca aacccacaat caagacatat atttgtaatg
    15661 gaatccattg tgttttccag tgccgcaact gcataattta accggactcc attcacatat
    15721 ttactaaaat tacagtgaaa tgtttttgca aacattcttg ataacacata tttgcttaca
    15781 cacaaatcgt atgccatttt ttcaagactg attttctctc taaaattttt agctacatat
    15841 tctaccgcat tataaatcag gtcatcactc cctactgtgc ttttatcaac cattggcatt
    15901 tctgcgaaaa catgggcaag aatcatctgt acataagcct gtatcagcat gggattcccc
    15961 tctgttattc ctgccagata ttttatggca tttactacat caggatgcac ttgctctttt
    16021 tttacaaccg ggttcttcgg gctgtatatc tgcaactctt tataatagga aggaaacagt
    16081 gtcggatcaa gatacaggta tattaccttg ttttcttttt tcccaaatac ttgataatga
    16141 tgtattacgt ttggaaacac gattgcaaaa tcaccctcat ccatgtgata caattcttgt
    16201 ccaactccaa gttcaatatc cccatccgtt acatacacta cctctattgc ttcatgtaaa
    16261 tgtggtggaa aatgcactgt tttcttccac tctaccacta ttccatcagt tctgttctca
    16321 tataccaata acacttgcaa gcaactcctc aaacaaactt agcggataat gaaggaatag
    16381 tgaatgtctt tttctgcact aatccgataa tcatcttcca catcacttcc ccagctatca
    16441 attccaccga ctcctcttac tgcaccatag acacaaagga ctgttcttct tgctggtggc
    16501 agttcctcat ggtgtgttgc gttttcaatc tctgatgctg tataaggcag gcacgaaaaa
    16561 gcaaatgcct tgtcgttttc ttctattctt aatgtctgtg gtgaactatc cgttctgcta
    16621 ttatcaagac ttgtatgtct tgtaatctcc agccactctg tatccattct cataccacat
    16681 tcctgtggaa ccagatatgg tgtcaggctc aaatctgata cctcataaat tcctttttct
    16741 gcccctgcct ttctgtccgg ataggtttcc cccgataatc ccttgtacat atatttatct
    16801 gcaagtgtcg gcataataaa cctcattccg aataccggaa gttccggcag tccctttact
    16861 cctgtgtaat ccacatccac cttgatattt ccagttacat caatggtata agatacaatg
    16921 actgttgtta ctggattgct gacagtctca taagtatatt tcacaattat ttccccggca
    16981 gccacatcac cgccatagct gttattgtcc ggagcatact gcttttgcaa ttcaccatcc
    17041 ataataactt cagttttttt acagtcaatg aacatatccg atgcgagcca gcttccactt
    17101 ttaatgtgaa acctgctgcc tctgtcatta tctgttaatg ctctccaaaa agtaggcttt
    17161 ggacaacgat acagccattc ataaccgttt tttactatag actccaaacc gccctgtgaa
    17221 taagagaata tatagtcaaa cccatctcca tgtacaccaa gtgtataatc tccatataca
    17281 actctcaatt tattcttatc tgtataagcc atagtaatac ctcacttcct gcatagctgg
    17341 tttttcctta cggtctgcaa atacaattcc atttcctgaa aactcataat cagaaggctt
    17401 atcatcaaag tccccgccat aacgcaaaac ttcttttcct gtcacttcat ctttcacgag
    17461 aagtgcctga tcaatgaaat cccagataaa tccaccgtgg tacatctcat acttatctat
    17521 taacttcata taagtaccaa gtcctcccat cgaattaccc atatcatgca tatactcaca
    17581 caaaagatac ggtttctttg gattattatt taaatattcc tccacttcat aaggctttgc
    17641 atacatcctg ctctctacat ctgatatggt ttcctcataa ttacggtcat agaaagagct
    17701 ttcataatga acaaatctgc catcctgctt ttccttgaag taagtattca ttgcttctat
    17761 gtcatcaccc gcataagatt catttcctaa agaccagaaa agaattgctg tatggttttt
    17821 aaaagtttca aaattactcc tagccctgtc aacaacagcc tcccgccatt gcggaataga
    17881 acaaggtacg ctgcacgatg gttcaatcgc accaagtttc tggaatgttc catgactttc
    17941 catattcgtt tctgccatta cataaatacc agctttatca cacaggtaat accacggtat
    18001 ctgatccgga taatggcatg tgcgtactgc attgatatta tttctaatca tacaatcaat
    18061 gtctgctgtc atttcatcca tactgatgct tcttcctgtc tttgcactcc actcatgacg
    18121 gtttactccg gtaatgacaa gacgtttacc atttaaatag attaccttgt caatcatttc
    18181 cagtcttctg aaacctatgt catatggaat tatctctaat atttctccat cttcgcctct
    18241 aagctctaca tatgcgtgat acagatatgg gcagtaatta tcccatgcct taacacttcc
    18301 aacctcagta tctatcactc ctacaagact tccagctttt tcctctaagg tgatattgtc
    18361 ctctgccacc tgattattct ctctgtcttt taaaaccaaa tgggcagata ctttctttcc
    18421 ttctggagca gatactttca tctttaccga taccctgccg cttatattgt ccttgtttag
    18481 tgttggctga aaccatacat cttccaaatg cacctctggc actgctttta aagttacatt
    18541 tctaaaaatt ccaaaaaatc ggaaaaagtc ctgatcctcc aaaaatgctg ccgtactcat
    18601 tttgtgaacc tgaactgcca gcacatttcc tttttctctg ataaatggtg tcagatcaaa
    18661 ttctgacggt gtaaaactat cctccgcata tcctacaaac tgaccattca gccacagata
    18721 catcgcttct tccacacctt caaaacagat acggattttc ttttcacgca tttgctcact
    18781 caaatcaaat cgtttgatat aagatccgac aggattatac tctgcctcgg aaaacattcc
    18841 tgcctcgtcc ccggtactct ccatactata cgcacccctg tgatattctt ttccctccca
    18901 cggatacatc gtattgatat agcgtatttt gtcatagcct gccagttcga tatgccccgg
    18961 aaccataatc ttatcaaatg aagatgcatc aaaattttcc tcatagaaat tttccggtct
    19021 gtccattaca tttttgctaa aagcaaactc ccattgtcca tttaatgact gcatcaaagg
    19081 attttctgat ttttccatat ctgcataatc catatagtaa caatggtcgc tgtgtgcgtc
    19141 caactggttt acacggaaca cttccggatt gtctaaccat ttcatatcag cgttcataat
    19201 aattctcctt tttttcttat tttctatata gcccctaaag tcaaactcca ggggctattt
    19261 tcattactga ttctgcatat tttcttttaa tttcatattt gcactctcta cattaaggaa
    19321 tgaaagaatg actgtaataa taatgtcaaa tataaacgga agccacagat acataaaata
    19381 catcatattg atacagctat ccggctgaac cgcattatca aggttaatat atccacttat
    19441 gtcaagcagc cagcctgaaa gtgcaacacc aatacctcca ccgagcttta cacctaatga
    19501 agtacaggag aacatggaac cgtcaatccg ctttccactc tttaaataag tatgttctga
    19561 acactgtgca attactgcac tcatgtctcc ctgccacggt ccttctccga gggatgtaag
    19621 aactgtaaat aacagcatca gcggaacact tcccagataa cctgccactg caaccatcaa
    19681 acggcatact gtagcaagca tataactata cttgtttaac ttatacattc ctttcatttt
    19741 tgaaaccagt gcaggtgtaa cggcaagtgc aatgatcaaa ggaatattat tcgcccatga
    19801 aaatacaccg aacaaattct tattcagcaa tacatatgtc ataaaaaaga ttcctacatt
    19861 caccatagaa gcacgaagct gctgaagaat atagatcaca caaatcattg aaaaatattt
    19921 attactaaag agaagtttta ttgtctgctt aaaagaaagt ttgtcatctt cctctcctgc
    19981 cacactgtca tcttttaatt cttcatctga cagctctttt accgaaaata cagcaagtgt
    20041 attggtaata atacctataa tacagtaaat aaatgcgata gttctccatg cggctgcacc
    20101 gccaccaaac atttctactg caccaacagt aacagactgg atgaccagat tcaatacttt
    20161 cctcgattcg cccatccgtc aaatcataac tcatatcaag aaaatctaat atctttgcct
    20221 cttggactgt cccatccaga agaattattt ttacttttct gcttatgtgc aaaatactac
    20281 atacaaaatc caaataatct ttaggagtta ttcctgtttt tataaattct ttgtgaaccg
    20341 attctctcca ttcgctcgct ccttcacctg aaaacgtgct ccatacgctt cgaacgactg
    20401 taagcacctt aactgcccaa tcaacatact ctttcctatt cacataatat atatgggcat
    20461 catcaatccc atcctagtta gtaattagaa tagtatatac attagcgtct ttttctgttc
    20521 acgtttttgg ggtattacca aatggaaata atttagtcaa aaagattgtg gttagatatt
    20581 tggtatcaaa aaacgtgata caaaacaggt gtttaaagcg attgcacatc aacaaggtgt
    20641 ttccgcatca gaagtaaaag aacgtattca atcaaccatc tgcatttacc acaagcacga
    20701 ctgccgcaga acgattgcgg cgatttccga cgcactgccg gatatggacg cagctatgcg
    20761 tccgctggca gagcagacga tccataaact gcaaaacata accgacgcag catttgagga
    20821 agcgcagttc accatgacgc tttcagacgc agagtaaaag atgacgcggg cgcggcagcc
    20881 gatgatgact gctgcgcccc gcgttttttg tgctaagctg tttccaatcg tagggattgt
    20941 taaaagtcaa gccgcatctt agataagttt gcccaaacac caatgatgtc agaagatgta
    21001 aaataataaa aatcagaagt ttcagattgt aggtatccct tttttgttgc aataccaatg
    21061 taaacaagtt cgtaattcgt cccatctgaa agatcaaaca cgaattttat tgtactaccg
    21121 tcgttagtag aatctgaatt tgcatctttc acaggcagct cagaaaaaaa cgtatatagg
    21181 tagtcaatat ccgcttcttc tgttagcgtt ttttccttgg tgtctgcctc tgagttagaa
    21241 tagtacgttt caattttcac aacatctgat gcagaaaaag gaaaaacaat atattctttc
    21301 tttccacaac cagaaattcc aaatataatt gccattgcga gaaaaaatgt aaagactttc
    21361 ttcat
//
