LOCUS       NZ_LR027880.1          19338 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LR027880.1 Roseburia intestinalis L1-82 chromosome 1, complete
            sequence.
ACCESSION   NZ_LR027880
VERSION     NZ_LR027880.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:36:21
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 530503
            Orig. end    :: 549841
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1536
                     /locus_tag="ctg1_502"
                     /transl_table=11
                     /translation="MEINNTGSTYGAAFRQKPIFFMSGKETVAFFEGKLKKNMTLQEDS
                     CTLGSNDTYRRQHTTYEVSDKKKGSTFLDLDFLIKDETSSLKGNLSDKKDVDFYNFSIP
                     FNRTIQNYFGVQIYMDMPEGCDYDLTLYDEYGNQVGKAEWDGEGRKTLTIPNWDTNTNK
                     YCIKIENKNGEEVSPHDYYKISFKVTENKEQEKTDAIREAFGNLHGAYSRKDENWREYL
                     DKYNEVLMDTEKNYTKEMEKLHQKQFESLPEEKQYKGGRTVDELLQDMAEGKTLDDAET
                     EYVKIFANLKDFEKAQQKAELKNDFSEDFVKDLESKGISRDELEGMQIKIESNGNVTVS
                     GIEDKEVREQVQKLVEEKYSDRMYQYYTGIADSVGNLSSNTYQYATDVQEVRRYLKGVT
                     GEDISLENLYLTPDGKIGGLPGKAADLINKTKDNAKIERIKDALINIIGHNRISGDLGI
                     PDFTSEFQFSNGAFSVADSGFTVDMAALDRRLTPQPHDNMYSDMYEYSFRKVL"
     protocluster    1..19338
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[539796:540543]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9294..10040
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..19338
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..19338
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             1573..2973
                     /locus_tag="ctg1_503"
                     /transl_table=11
                     /translation="MVITRTVEMHAQLVGYDFKKKGLPTDKNIAVENSKVSNDYFWKTN
                     KYTDQDVFGRTLDLTALINKPDGYLKGSLSDTEDVDYYEFNITEYRALSFVKDTYNRDI
                     TITLDHIPEGYDYEMVLYDEEGNQVGIGKENGNGGLSITIPNWNSDNTGYTVKVQAKNG
                     STVNPDAEYHLSFQTTQADKSHGAYQEMAEVQKYAGTVRKQMQEGLIDTEEMRAIKEIR
                     QKYKTYYTEQMEKLHQEQAEAVMQGGAVPDDEQIHNLLEKKAAGKELTEQENALLNIFC
                     TATELDSANASAKMNTTVKDRISVDLQEAGMDISDSTFSIKIGADGQVSVDGINDNAMK
                     QKIEDVLSKYSDDLMDIYFSMDSEIQALSDKEKYLLQAAVDVEKFLYKATGGSVSLGDL
                     SVENTAIHGLPKTLDDLLNNPGDNLTYQDYASDIREILAYNRTQHKDIMSELNVQFVIA
                     DGTFQIKD"
     CDS             3024..3989
                     /locus_tag="ctg1_504"
                     /transl_table=11
                     /translation="MRIENGYLQQSMLCSKNNRNAVGNFSDTMNKAQECISNKISTRDS
                     YVNSTDYSNFGIYTQNSISQDIELPIETERYKIEDATYVNGVAAYEIVDKQTGKDFYIR
                     EDQLAIQRDEKTGMEFLINMDQPFSYNVTMTSELKNLLNDLSDKRNIDIKEIPLQGGLV
                     VKRDPKTGLNYLSIKGNEAQGVSVIITSDKDIETLNKLADEFQKYPVSSQRSTAGLYAL
                     LEISGNLKREKDGFTFLTPNGVTYIPYDGDSSKAWEIDMPGSCYATARKCLAAENDCAD
                     ISAWTKNLKGIKIYYGDNYGTTQTNNVYKVDDLGRYYMFA"
     CDS             4116..5180
                     /locus_tag="ctg1_505"
                     /transl_table=11
                     /translation="MNIDYSQFYRGTTNIPSYGNGIYKKDTLVKYEFNTTDEHGNKIMD
                     KMSREETLQAMKDIGSQYGDAVIVEFSGDGMAALVENKKGIVDANVTQEQRESMEARNA
                     AFQKEITQVDNSLELPAYSGMYGADKAVASAVENCSKEEQGFVYDIIRQNFLVGNTGSM
                     TEEERQANISLGMKKAEYAAENFIPEDSRKPFLEAMESIAKLASAGKADNNGNMDYGVG
                     KGTYLGHGSNLVKTTNALDMMRTMDGSAYTEYQKISKESSNEDRQLNALKYLTNWYEGA
                     VKKNPSMVDNYEKQSEEYVEKNVKDQKLDATFSDIKTENKAAFFESLKVFQNNNPNFLS
                     SIINRELASKFWSI"
     CDS             5438..5746
                     /locus_tag="ctg1_506"
                     /transl_table=11
                     /translation="MGNVECLPDDPALRLKILSKVGFLYFGAIEDKDRQLSGFLEVLVS
                     YHGISKLTIAKMAGVEENDIDRLLANPPEKDEIEVKYKIAVTVMELRFWLKDCESPI"
     CDS             5773..6423
                     /locus_tag="ctg1_507"
                     /transl_table=11
                     /translation="MKNKSINQVSIINGEDGPTSVFIFGEAQKQSLKIRIRNAIYQSRR
                     KRIEKRIAVNPHTLAEVVQYAKDHYDLVEINPAATNWIERQKNLKASLIMQHKPELLGQ
                     RKDIPKPDFHNEESVKNFLNEMEIRNKLIDQMPDNVIPMDFHLYEIKIGEDLMEIEVDY
                     TWNIFGISYSGNKSVIKRFKKIARDLYCYYGVSEEDIKNRTKRYSSLVTELSS"
     CDS             6895..7230
                     /locus_tag="ctg1_508"
                     /transl_table=11
                     /translation="MKAEKKEINIQIGKRLQTARENSGYTQEVFAETLDVGVEHYRKIE
                     SGVYGLQPEKMLILYEKYRIEPTYLVTGDTNHKVDIELFLANCSREERDAFIDRMLAYM
                     RKLMTGR"
     PFAM_domain     6940..7104
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_508_0001"
                     /evalue="1.50E-06"
                     /label="ctg1_508"
                     /locus_tag="ctg1_508"
                     /protein_end="70"
                     /protein_start="15"
                     /score="28.2"
                     /tool="antismash"
                     /translation="LQTARENSGYTQEVFAETLDVGVEHYRKIESGVYGLQPEKMLILY
                     EKYRIEPTYL"
     CDS             7289..7993
                     /locus_tag="ctg1_509"
                     /transl_table=11
                     /translation="MRVAICDDNQQDIERIRRYTLRMIDYAVEYVFYTRPEELLRECAD
                     AEQKPDMYILDIEMPGMDGLAVAKQIRETDSKALLVFLTSYTKYMPSVFEVVTFDFIPK
                     PISEERLRVLFEKAGTYLNLTNQSFSFSYRRVRYSLKFDEILYLEKRGRQAIIHTKKMK
                     YQSNMNLNEIWGKLDERMFAAVHGSFIVNLKHVHSVSSGMVMLTDGTELGVTRGYRKEL
                     TKKHIAFVQGGM"
     PFAM_domain     7295..7624
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_509_0002"
                     /evalue="2.50E-16"
                     /label="ctg1_509"
                     /locus_tag="ctg1_509"
                     /protein_end="112"
                     /protein_start="2"
                     /score="59.9"
                     /tool="antismash"
                     /translation="VAICDDNQQDIERIRRYTLRMIDYAVEYVFYTRPEELLRECADAE
                     QKPDMYILDIEMPGMDGLAVAKQIRETDSKALLVFLTSYTKYMPSVFEVVTFDFIPKPI
                     SEERLR"
     PFAM_domain     7700..7960
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_509_0003"
                     /evalue="2.50E-17"
                     /label="ctg1_509"
                     /locus_tag="ctg1_509"
                     /protein_end="224"
                     /protein_start="137"
                     /score="63.0"
                     /tool="antismash"
                     /translation="YSLKFDEILYLEKRGRQAIIHTKKMKYQSNMNLNEIWGKLDERMF
                     AAVHGSFIVNLKHVHSVSSGMVMLTDGTELGVTRGYRKELTK"
     CDS             7995..9188
                     /locus_tag="ctg1_510"
                     /transl_table=11
                     /translation="MALYGVRLVINLFDLCIYRRYLEEFIGNRKTSMEFSVLLLIVCEL
                     IGSAVNQMGISWLNFVTMVAILCVYVCQYEAGIVSRLIAVLLYMGIMGVAEPLGYLFNK
                     AFMEKVLDDTTVSYYFIVFFMALLKATIVEVFCRLKSGKSIRLSAMPKETQYMLTMIPL
                     CSLISCFLLIEVAKELISAQMVVLCMCIIFVIIITNYVIFLMIEKYTTVEEKQHEEEMI
                     QREILYRNEYYQDMERYQEQIQDIRLAEEIIYSANPVVNAILKVKSVKAKEKEIPMQVT
                     TLLPQRVSVDIGDMGVLYGNLLDNAIEAAMAVEQEKRYVHVESKFQEGRLLLSIKNSKP
                     SGTSSYRQTSKKDKIKHGRGIRSVRKVAEKYGGELLLKDQGEHFEAALLLNGITKLE"
     PFAM_domain     8874..9164
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_510_0004"
                     /evalue="7.00E-20"
                     /label="ctg1_510"
                     /locus_tag="ctg1_510"
                     /protein_end="390"
                     /protein_start="293"
                     /score="70.9"
                     /tool="antismash"
                     /translation="DMGVLYGNLLDNAIEAAMAVEQEKRYVHVESKFQEGRLLLSIKNS
                     KPSGTSSYRQTSKKDKIKHGRGIRSVRKVAEKYGGELLLKDQGEHFEAALLL"
     CDS             9294..9455
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_511"
                     /sec_met_domain="TIGR04223 (E-value: 8.7e-11, bitscore:
                     39.6, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKRNWMYRLSSKSMSVMAALALMVTTMATNRSCMWYLGQDKMPE
                     DSKKLRRF"
     aSDomain        9330..9440
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_511_0001"
                     /evalue="9.60E-11"
                     /identifier="TIGR04223"
                     /label="ctg1_511"
                     /locus_tag="ctg1_511"
                     /protein_end="49"
                     /protein_start="12"
                     /score="39.6"
                     /tool="antismash"
                     /translation="KSMSVMAALALMVTTMATNRSCMWYLGQDKMPEDSKK"
     CDS             9459..10040
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_512"
                     /sec_met_domain="AgrB (E-value: 1.8e-33, bitscore: 113.4,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRWLSHRMVERGIIKEEEQELYQFGIRNGMILLLNVVTALVIGL
                     LTEQLAVVAVFTLSFMVLRSYTGGYHSDSRIFCYLGSNLVLLVPVYTQAVFYKTSLAWL
                     LAVLLVSAGIIFLLSPMHSKNRKLDKEEQKHFGRKARLIAALELAVLGILWHAGQVLYA
                     YAVYTGICITALFMLIGKAQLWIQSHTENR"
     PFAM_domain     9471..9995
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_512_0005"
                     /evalue="1.80E-32"
                     /label="ctg1_512"
                     /locus_tag="ctg1_512"
                     /protein_end="179"
                     /protein_start="4"
                     /score="112.3"
                     /tool="antismash"
                     /translation="LSHRMVERGIIKEEEQELYQFGIRNGMILLLNVVTALVIGLLTEQ
                     LAVVAVFTLSFMVLRSYTGGYHSDSRIFCYLGSNLVLLVPVYTQAVFYKTSLAWLLAVL
                     LVSAGIIFLLSPMHSKNRKLDKEEQKHFGRKARLIAALELAVLGILWHAGQVLYAYAVY
                     TGICITALFMLI"
     CDS             10415..10840
                     /locus_tag="ctg1_513"
                     /transl_table=11
                     /translation="MSEWIRIRVKDFYKDAVGELEYTYVTREVYEALVDTFRKEAHAQE
                     MRDIRHTTKDGYTEGETEDLVELTGESVEDTVIRQMEIETLQKAMQSLTPVQRERLHFY
                     FFEGMTYRQIAAKEGVGEKNIRESINGAVKKIKKYFD"
     aSDomain        10451..10831
                     /aSDomain="TIGR02937"
                     /aSTool="tigrfam"
                     /description="sigma70-ECF: RNA polymerase sigma factor,
                     sigma-70 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_513_0002"
                     /evalue="6.10E-14"
                     /identifier="TIGR02937"
                     /label="ctg1_513"
                     /locus_tag="ctg1_513"
                     /protein_end="139"
                     /protein_start="12"
                     /score="49.9"
                     /tool="antismash"
                     /translation="YKDAVGELEYTYVTREVYEALVDTFRKEAHAQEMRDIRHTTKDGY
                     TEGETEDLVELTGESVEDTVIRQMEIETLQKAMQSLTPVQRERLHFYFFEGMTYRQIAA
                     KEGVGEKNIRESINGAVKKIKKY"
     PFAM_domain     10679..10828
                     /aSDomain="Sigma70_r4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04545.18"
                     /description="Sigma-70, region 4"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_513_0006"
                     /evalue="1.70E-07"
                     /label="ctg1_513"
                     /locus_tag="ctg1_513"
                     /protein_end="138"
                     /protein_start="88"
                     /score="30.7"
                     /tool="antismash"
                     /translation="AMQSLTPVQRERLHFYFFEGMTYRQIAAKEGVGEKNIRESINGAV
                     KKIKK"
     CDS             11546..11941
                     /locus_tag="ctg1_514"
                     /transl_table=11
                     /translation="MKKEDTEMMLRIFETERAGYAYLYPSDGGERKEDYISTTAENIAN
                     YIGSHMFEAEKIVITDMCDRLILDTCGYFINSCPNQEFCKEINPFLIPIQMGEKDAGEV
                     LSVSRDVSEQYFREEDEAATMAEIGMM"
     CDS             12023..12181
                     /locus_tag="ctg1_515"
                     /transl_table=11
                     /translation="MMEGGANEVRYKIAEFLLKRMHEDKLLTEEEWEKIRVLNVKTFSP
                     ELAKVYL"
     CDS             12272..13888
                     /locus_tag="ctg1_516"
                     /transl_table=11
                     /translation="MAKKVTVIKAAKAQKHTQEERRLKVCGYARVSTGSQAQATSYTAQ
                     VEYYTEKIESNPLWEFAGVYADEGISGTNVKHRDEFQMMISDCEDGNIDLILTKSITRF
                     ARNTVECIQTIRKLKEIGVGIYFEKENINTLSEKSELFITILASVAQGESENISSNNRW
                     AIQKRFQDGTYIISTPAYGYGKDEDGNLVIIESEAETVRWIYESYLNGMGVYVIAKALN
                     QKGIPTIRGAEKWQDGVIQDILKNPIYEGDMLQQRTYTETRFPFVRRVNNGQRNQYLIK
                     DSHPPIVTHEEAEAVRNLMAYRVDVLHMNKSDYTKRYLFSGRIICGECGRTFRRQKIYI
                     GKPYEKIIWTCSGHVEDKERCCLKAIREDVLHRAFTDMWNKLYTNQGTILEPLLKELTE
                     LVAARQDSEEIRQLDKEIKDISGQSQILNQVMRKGYMDSALFMESSSKLGWQLTECRRK
                     KTLLTRKLRRTKEIVRTEQLIQLIAEQDGLMEEFDEQLFKMTAEKIVVSKEHDITFCLY
                     NGLKLTERGGGQDAVAHANRL"
     PFAM_domain     12347..12790
                     /aSDomain="Resolvase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00239.23"
                     /description="Resolvase, N terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_516_0007"
                     /evalue="1.50E-29"
                     /label="ctg1_516"
                     /locus_tag="ctg1_516"
                     /protein_end="173"
                     /protein_start="25"
                     /score="103.0"
                     /tool="antismash"
                     /translation="CGYARVSTGSQAQATSYTAQVEYYTEKIESNPLWEFAGVYADEGI
                     SGTNVKHRDEFQMMISDCEDGNIDLILTKSITRFARNTVECIQTIRKLKEIGVGIYFEK
                     ENINTLSEKSELFITILASVAQGESENISSNNRWAIQKRFQDGT"
     PFAM_domain     12857..13171
                     /aSDomain="Recombinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07508.15"
                     /description="Recombinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_516_0008"
                     /evalue="8.00E-21"
                     /label="ctg1_516"
                     /locus_tag="ctg1_516"
                     /protein_end="300"
                     /protein_start="195"
                     /score="74.5"
                     /tool="antismash"
                     /translation="SEAETVRWIYESYLNGMGVYVIAKALNQKGIPTIRGAEKWQDGVI
                     QDILKNPIYEGDMLQQRTYTETRFPFVRRVNNGQRNQYLIKDSHPPIVTHEEAEAVRNL
                     M"
     PFAM_domain     13226..13408
                     /aSDomain="Zn_ribbon_recom"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13408.8"
                     /description="Recombinase zinc beta ribbon domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_516_0009"
                     /evalue="1.00E-11"
                     /label="ctg1_516"
                     /locus_tag="ctg1_516"
                     /protein_end="379"
                     /protein_start="318"
                     /score="45.2"
                     /tool="antismash"
                     /translation="LFSGRIICGECGRTFRRQKIYIGKPYEKIIWTCSGHVEDKERCCL
                     KAIREDVLHRAFTDMW"
     CDS             13860..14759
                     /locus_tag="ctg1_517"
                     /transl_table=11
                     /translation="MQWHMPIGYKVVDGKITICEEQRKIVEQIFTDYDSGVAAGRIAQN
                     LKGRKICNAKGKVSWTHAFIGRILENPSYLGTEYYPQLIGEELFERVQRRREKVRAELG
                     RADHRSGRDERILFGGVIWCAECGAVCSHIQPSHKKERGGTAKWKCKSYVIGRAKNCRN
                     SFITDGQAKQVCVEAINAVIRNKGLLRVQRQEEKVSPQYRVLERNLQRMKEEQERTETD
                     LMKLLYERAEERYRTLEVRDGEFRTEEVKNILAGKKELETFDENLYRKIIARIWVHGGN
                     MAEVELINGSRVTAGYKD"
     PFAM_domain     13917..14150
                     /aSDomain="Recombinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07508.15"
                     /description="Recombinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_517_0010"
                     /evalue="2.10E-10"
                     /label="ctg1_517"
                     /locus_tag="ctg1_517"
                     /protein_end="97"
                     /protein_start="19"
                     /score="41.0"
                     /tool="antismash"
                     /translation="EEQRKIVEQIFTDYDSGVAAGRIAQNLKGRKICNAKGKVSWTHAF
                     IGRILENPSYLGTEYYPQLIGEELFERVQRRRE"
     CDS             14772..16406
                     /locus_tag="ctg1_518"
                     /transl_table=11
                     /translation="MAETAKKISMIPAKVQYDRNVKLSEKKMKVAAYCRVSTELEEQDS
                     SYEAQVEYYTSKISENENWKNAGIYADDGKSGTNTKKRADFNAMIQDALAGKIDMILTK
                     SVSRFARNTVDSLVTIRKLKEKNVAVVFEKEGINTLEGTGEILITILSSLAQEESRNIS
                     ENIRWGVVRKFEKGKVIVNCTKFMGYTKNEDGDLVIVPEEAEIVKLIFRLYLEGYSTGK
                     IAKHLEEQGIKTATGQDKWHSTVIDKMLRNEKYMGDALLQKTYTVDFMTKKKVKNTGIV
                     PQYYVEDDHEAIIPKELFYRVQEEMMRRASLCKAAVTRKKNQKSRYSSTYALTGMLICG
                     KCGQEYRRVTWARNGKKKVVWRCSNRLTNGVKKCGESETLEENALNRAVMEAIHRITSD
                     DMEFMENFRQNIIHVIGNYSTAKESEEYEEKIKEKQEEMVALIAENAKTGSYTPEFDER
                     YRTIAEEINALKEAQKTARNEKWMADSYEQRIQDIDHYLSTSTCQIPEFDNDLVRRLIS
                     TIKVESSEKLLIQFQSGIVMEQEIRYE"
     PFAM_domain     14859..15305
                     /aSDomain="Resolvase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00239.23"
                     /description="Resolvase, N terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_518_0011"
                     /evalue="6.10E-33"
                     /label="ctg1_518"
                     /locus_tag="ctg1_518"
                     /protein_end="178"
                     /protein_start="29"
                     /score="114.0"
                     /tool="antismash"
                     /translation="VAAYCRVSTELEEQDSSYEAQVEYYTSKISENENWKNAGIYADDG
                     KSGTNTKKRADFNAMIQDALAGKIDMILTKSVSRFARNTVDSLVTIRKLKEKNVAVVFE
                     KEGINTLEGTGEILITILSSLAQEESRNISENIRWGVVRKFEKGK"
     PFAM_domain     15372..15692
                     /aSDomain="Recombinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07508.15"
                     /description="Recombinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_518_0012"
                     /evalue="5.20E-26"
                     /label="ctg1_518"
                     /locus_tag="ctg1_518"
                     /protein_end="307"
                     /protein_start="200"
                     /score="91.1"
                     /tool="antismash"
                     /translation="PEEAEIVKLIFRLYLEGYSTGKIAKHLEEQGIKTATGQDKWHSTV
                     IDKMLRNEKYMGDALLQKTYTVDFMTKKKVKNTGIVPQYYVEDDHEAIIPKELFYRVQE
                     EMM"
     PFAM_domain     15768..15950
                     /aSDomain="Zn_ribbon_recom"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13408.8"
                     /description="Recombinase zinc beta ribbon domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_518_0013"
                     /evalue="9.70E-12"
                     /label="ctg1_518"
                     /locus_tag="ctg1_518"
                     /protein_end="393"
                     /protein_start="332"
                     /score="45.3"
                     /tool="antismash"
                     /translation="LTGMLICGKCGQEYRRVTWARNGKKKVVWRCSNRLTNGVKKCGES
                     ETLEENALNRAVMEAI"
     CDS             16612..17193
                     /locus_tag="ctg1_519"
                     /transl_table=11
                     /translation="MNYEQLIEELREEMLQLVNTKCDALLQMYRSGEMRTDMKDTIRES
                     SLITVSPAELKGKRPLAVQFAPGEWIETPTWRKVAQRILQTYNEQPDIHERFMEMCGKV
                     AGRWRTILGSSPEEMDVPLKVDEELYFEGKFDTEAMLNMLEKKVLEPAGVDYSSIKIRY
                     MGKGQEVAKSLEQDVLEQEGQEQHAPVQTM"
     CDS             complement(17401..17973)
                     /locus_tag="ctg1_520"
                     /transl_table=11
                     /translation="MVANGSLKKQRKNPNDPARFVNKVAVTNEGEKAKIHYYLDTDKIA
                     EEEMYDGLYAVCTDLLDDDVADILKVSEGRWQIEDCFRTMKTDFEARPVYLNREDRIKA
                     HFLTCFLALLHFRLLNRSLKGTYTTEQLLHTLKDIKFTDIEEQGFMPVYERQEITDDLH
                     ETCGFRTDYQFITKRKMKGIQKKSKRR"
     PFAM_domain     complement(17635..17907)
                     /aSDomain="DDE_Tnp_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01609.23"
                     /description="Transposase DDE domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_520_0014"
                     /evalue="3.30E-08"
                     /label="ctg1_520"
                     /locus_tag="ctg1_520"
                     /protein_end="113"
                     /protein_start="22"
                     /score="33.5"
                     /tool="antismash"
                     /translation="KVAVTNEGEKAKIHYYLDTDKIAEEEMYDGLYAVCTDLLDDDVAD
                     ILKVSEGRWQIEDCFRTMKTDFEARPVYLNREDRIKAHFLTCFLAL"
     CDS             complement(18169..19338)
                     /gene_functions="other (smcogs) SMCOG1237:transposase
                     (Score: 353.5; E-value: 2.8e-107)"
                     /gene_kind="other"
                     /locus_tag="ctg1_521"
                     /transl_table=11
                     /translation="MKIYVGIDIAKLNHFAAAISSDGEIIIEPFKFTNDADGFQLLVSK
                     LESFDKNSLIIGLESTAHYGDNLVRYLVTELYQVCVLNPIKTCQMRKNNVRKTKTDKVD
                     TYVIAKTLMMQDNLRFVSFFDLDMMDLKALGRFRQKTIKQRTRLKIQLTTYVDQVFPEI
                     QYFFKSGLHQHAVYALLKETPSPKEIASMHMTHLANLLKVNSHGHFTKEQAKELRVLAQ
                     KSVGANDSAISIQITQTIQQIELLDSQLEKIEAEMTDIMKFNDSVIMTIPGIGYINGGM
                     ILGEIGDIHRFSNPNKLLAFAGLDPSVYQSGNFQAKTTRMSKRGSRVLRYALVNAAWNV
                     VRNNATFKAYYDAKRAEGRSHYNALGHCAGKLVRVIWKMLTGEVEFNLE"
     PFAM_domain     complement(18286..18540)
                     /aSDomain="Transposase_20"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02371.18"
                     /description="Transposase IS116/IS110/IS902 family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_521_0016"
                     /evalue="4.10E-28"
                     /label="ctg1_521"
                     /locus_tag="ctg1_521"
                     /protein_end="351"
                     /protein_start="266"
                     /score="97.6"
                     /tool="antismash"
                     /translation="VIMTIPGIGYINGGMILGEIGDIHRFSNPNKLLAFAGLDPSVYQS
                     GNFQAKTTRMSKRGSRVLRYALVNAAWNVVRNNATFKAYY"
     PFAM_domain     complement(18856..19326)
                     /aSDomain="DEDD_Tnp_IS110"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01548.19"
                     /description="Transposase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_521_0015"
                     /evalue="1.70E-42"
                     /label="ctg1_521"
                     /locus_tag="ctg1_521"
                     /protein_end="161"
                     /protein_start="4"
                     /score="145.0"
                     /tool="antismash"
                     /translation="VGIDIAKLNHFAAAISSDGEIIIEPFKFTNDADGFQLLVSKLESF
                     DKNSLIIGLESTAHYGDNLVRYLVTELYQVCVLNPIKTCQMRKNNVRKTKTDKVDTYVI
                     AKTLMMQDNLRFVSFFDLDMMDLKALGRFRQKTIKQRTRLKIQLTTYVDQVFP"
ORIGIN
        1 atggaaataa acaatactgg ttctacatat ggggcagcat ttcgtcaaaa accgattttt
       61 ttcatgtctg gaaaggaaac agtggcattt tttgaaggaa aactgaagaa aaatatgaca
      121 cttcaggaag attcctgtac acttggcagc aatgacactt atcgcagaca gcataccact
      181 tatgaggttt cggacaagaa gaagggaagt acgtttctgg atctggattt tctgattaag
      241 gacgaaacca gcagtctgaa aggaaatctc agtgataaaa aggatgtgga tttctacaac
      301 ttttccattc catttaatcg aaccatacag aattattttg gggttcaaat atacatggac
      361 atgccggaag gctgtgatta tgacctcacc ttatatgatg aatatggcaa tcaggtcgga
      421 aaggcagaat gggacggaga aggacgtaaa acactgacca tcccgaactg ggatacaaat
      481 accaataaat attgtatcaa aatagaaaac aaaaatgggg aagaagtttc tccgcatgat
      541 tattataaaa tcagtttcaa ggttacggaa aataaagaac aggaaaagac cgatgccata
      601 agggaggcat tcgggaacct tcacggtgca tacagccgga aagatgaaaa ttggagggaa
      661 tacctcgaca aatataatga agtcctgatg gatacagaga aaaattatac aaaagaaatg
      721 gagaaactcc accagaagca gtttgaaagt ctgccggaag aaaaacaata caaaggcggg
      781 cgcacagtgg atgaattgtt gcaggacatg gcagaaggaa agacactgga tgatgcggaa
      841 acggagtatg tgaagatttt tgcaaacctg aaagattttg agaaagcaca gcagaaggcg
      901 gaactgaaaa atgatttttc cgaggatttt gtaaaggatc tggaaagcaa aggtatctcc
      961 cgtgatgagc tggagggaat gcagataaag attgaaagca atgggaatgt aacagtgagc
     1021 ggtatcgaag ataaggaagt ccgggaacag gttcagaaac tggtagagga aaagtacagt
     1081 gaccggatgt atcagtatta cacaggaatt gctgacagtg tgggaaatct gtcgtccaat
     1141 acctaccagt atgccacgga tgtgcaggaa gtcaggcgtt acttaaaagg ggttacggga
     1201 gaagatattt ctctggagaa cctttacctg acaccagacg gaaagattgg cgggctgccg
     1261 ggaaaagctg ctgatctgat caacaaaaca aaggacaacg ccaagataga gcggataaag
     1321 gatgcattga taaatatcat aggacataac cggataagtg gtgatctggg gattcctgat
     1381 tttacttcgg agtttcaatt cagcaatgga gcgttctctg tggcagacag tggttttacg
     1441 gtggatatgg cggcattgga tagaaggctg acgccccaac cgcatgataa catgtattcg
     1501 gatatgtatg agtacagttt cagaaaagta ttatgattat gaaaagtaat tatacacaag
     1561 gagaatgaac agatggtaat aacccgcaca gtagagatgc atgcgcagct tgtgggatat
     1621 gattttaaga aaaaaggttt acccactgat aaaaatattg cagtagaaaa tagtaaagtt
     1681 tccaatgatt atttctggaa aacaaataaa tatacggatc aggatgtgtt tggaagaaca
     1741 ctggatctga cggcacttat caataagccg gacggatatt taaagggaag tttatcggat
     1801 acggaggatg tggactatta cgaattcaat attacagagt accgggcatt aagttttgtg
     1861 aaggatacct ataataggga tattactatc actttagatc atataccgga aggctatgat
     1921 tatgagatgg ttttgtatga tgaggaaggc aatcaggtcg gcattgggaa agagaatgga
     1981 aatggcggtc ttagtattac cataccgaac tggaattcgg acaacacggg ttataccgta
     2041 aaggtacagg caaagaatgg ttcgacggta aacccggatg ccgaatatca tctttctttc
     2101 cagacaacgc aggcggataa aagccatgga gcttatcagg aaatggcaga ggttcagaaa
     2161 tatgcaggga cagtccggaa gcagatgcag gaaggcttaa tcgatacgga ggagatgcgt
     2221 gcaattaagg aaatccggca gaagtacaaa acttattata cagagcagat ggagaaactg
     2281 catcaggaac aggcagaagc tgtcatgcag ggtggggcag tgccggatga tgagcagatt
     2341 cacaatttac tggaaaagaa ggcggcaggc aaagaactga cggagcagga aaatgccctt
     2401 ttaaatatct tttgtaccgc aacagagctg gatagtgcga atgcaagtgc aaaaatgaat
     2461 accacagtaa aagacaggat atctgttgat ttgcaagaag cgggaatgga tatttcagat
     2521 tccacgtttt ccataaaaat tggggcggat ggtcaggtaa gtgtcgatgg cattaatgat
     2581 aatgcaatga aacagaagat agaggatgtt ttgtcaaagt attcggatga tctgatggat
     2641 atttattttt ctatggattc ggaaatacag gcattgtccg ataaagaaaa gtatctgtta
     2701 caagctgcgg tggatgtgga aaaattttta tataaggcaa ctggcggcag tgtatcgctt
     2761 ggagaccttt ccgtggaaaa tacagcgata catggtctgc cgaaaacact ggatgacctg
     2821 ttaaataatc cgggcgataa cctgacctat caggattatg caagcgatat ccgggaaatt
     2881 ttagcatata accggacaca gcacaaagat attatgtctg agttaaatgt acagtttgtt
     2941 atagcagacg gtacatttca gataaaagat taaagtttat aatggagtat tcaataaaac
     3001 ccaagtgatt gggagggaga atcatgagaa tagagaatgg ttacttacaa caaagtatgt
     3061 tatgcagtaa aaataataga aatgcagtag gaaatttttc tgatacaatg aataaagccc
     3121 aagagtgtat aagtaataag attagcacaa gggattccta tgtaaacagt acagattata
     3181 gtaactttgg aatttataca caaaatagta tctctcaaga tattgaatta ccaatagaga
     3241 cagaaagata taaaattgaa gatgctacat atgtgaatgg agtagcagca tatgagattg
     3301 tagataagca gacaggaaaa gatttttata taagagaaga tcaattagca attcaaagag
     3361 atgagaaaac aggaatggag ttcctgatta atatggatca gccattttcg tataatgtaa
     3421 ccatgacaag tgaactgaaa aatcttttga atgatttgtc tgacaaaaga aatattgata
     3481 taaaggagat accgctacag gggggattgg tagtaaaacg tgatccaaag acagggttaa
     3541 attatttgtc gataaaggga aatgaggcac aaggagtttc ggtaatcata acatccgata
     3601 aagatataga gacgctgaat aaattagctg atgaatttca aaaatatccg gtaagttcac
     3661 agcggtctac ggcaggatta tatgctttac ttgagatatc aggaaatctg aaacgcgaaa
     3721 aagatggttt tacatttttg actcctaatg gagttacata tattccgtat gatggtgatt
     3781 ccagcaaagc atgggaaatt gatatgccgg gttcctgtta tgctactgcc agaaaatgtt
     3841 tggcggcaga aaatgattgt gcagacataa gtgcatggac aaaaaatttg aaaggaataa
     3901 agatatatta tggtgataat tatggcacca ctcagacaaa taatgtatat aaagttgatg
     3961 atttaggcag atattatatg tttgcataag atatatatac aagtatgaaa ctataaaaat
     4021 atagtatgtt ttatgtggta aaaatattgt atttatgaga cttttggtat ttcacaaata
     4081 cctaagaaaa aataaagtag aggagagtgt atattatgaa tattgattac agtcagtttt
     4141 acagaggaac aacgaatatt ccctcatatg ggaatggtat atataagaaa gacacccttg
     4201 taaagtatga atttaacact acagatgaac atggcaataa gattatggac aagatgtcaa
     4261 gggaagaaac cctgcaggcg atgaaggaca tcggttcgca gtatggagat gcggttattg
     4321 ttgaattttc gggagatgga atggctgcac ttgtggaaaa caagaaaggt atagtggatg
     4381 ccaatgtaac acaggagcag cgggaatcaa tggaggcgag aaatgcagcg ttccaaaaag
     4441 aaattacgca ggttgataac tcactagaac ttccggcata ttccggaatg tatggtgcag
     4501 acaaggcggt tgcatctgcg gtggagaact gcagcaaaga ggaacaggga tttgtgtatg
     4561 atatcatccg tcagaatttc cttgttggaa atactggctc tatgacagag gaagaacggc
     4621 aggcaaatat ttcacttggt atgaaaaaag cggaatatgc ggcagagaat tttatcccgg
     4681 aagatagcag aaaaccattt ttggaagcaa tggagtctat cgcaaagctt gcgagcgcag
     4741 gaaaagctga caataacgga aatatggact atggagtagg gaaaggtaca tatcttggac
     4801 atggtagcaa tcttgtaaag actacaaatg cgcttgatat gatgaggacg atggacggca
     4861 gtgcatacac ggaatatcag aagattagta aagaaagcag caatgaggac agacagctta
     4921 atgcattaaa ataccttaca aattggtatg aaggggcagt gaaaaagaat ccttcgatgg
     4981 ttgataatta cgaaaagcag tcggaggaat atgtggagaa aaatgtaaaa gatcagaagc
     5041 tggatgcaac tttttcagat ataaagacag agaataaagc ggcttttttt gaaagtctga
     5101 aagtgttcca gaataataat cctaattttc tctcatctat cataaatcgg gagctggcat
     5161 ctaaattttg gagcatttga taaacgtaga ttggaaaagt tataattgct cggaaaatgg
     5221 aagataacaa caataaagtg tagagtgtgc ctttcacata gggacacttg ttacaagcaa
     5281 tattgtaaat gatacaagtg gagattaagg cacaaatatg ataaaaacaa aaaatatttc
     5341 agaaatgttg acttctttaa ttgaggagta tcgttttaat aaaaatactc tttcaaaata
     5401 tttagaaata actgaagaaa cagtagattg agtagtaatg ggcaatgtgg aatgtttgcc
     5461 agatgatcct gcattgcgtc ttaaaatact tagtaaagta ggatttctgt attttggagc
     5521 gattgaagat aaggataggc aattaagcgg ttttttggaa gtgcttgttt cctatcatgg
     5581 catatccaag ctaacgatag caaaaatggc tggtgttgag gaaaatgata ttgacaggct
     5641 tttagccaat ccaccagaaa aagatgaaat cgaagtaaaa tataaaattg ctgtgactgt
     5701 tatggaattg cgattttggc taaaagattg tgaatcaccg atataatcgg gatttgtgag
     5761 tagagggcac ttatgaaaaa taaaagtatc aatcaagttt ccataataaa tggtgaagat
     5821 ggtcccacaa gtgtttttat atttggagaa gctcaaaagc aatctctaaa gattagaatc
     5881 cgaaatgcta tctatcaatc cagacgaaaa aggatagaaa agagaatagc ggtcaacccg
     5941 catacccttg cggaagtggt gcaatacgca aaggatcatt atgatttagt ggaaatcaat
     6001 cctgccgcaa caaattggat agaacgacag aaaaatctaa aagctagttt gattatgcag
     6061 cataaaccag aacttttggg ccaaaggaag gatattccaa aaccagattt tcataatgaa
     6121 gaatctgtta aaaatttttt gaatgaaatg gaaattagaa ataaattgat tgaccaaatg
     6181 cctgataatg taattcccat ggattttcat ttatatgaaa taaaaattgg tgaggattta
     6241 atggaaatag aggtagatta tacctggaat atatttggaa tatcttactc tggaaataag
     6301 tcggtcataa aaaggtttaa gaaaatagcc agagatttat attgttatta tggtgtcagt
     6361 gaggaggata taaagaaccg gacaaaaaga tattcttcac tggtaacgga attgagttca
     6421 taattcagaa ttttaaatag aagtaggatt tctgtatttt ggagcgattg aagataagga
     6481 taagcaatta agcggttttt tggaagtgct tgtttcctat catggcatat ccaagctaac
     6541 gatagcaaaa atggctgatg ttgaggaaca ggatattgac aggcttttag ccaatccgcc
     6601 agaaaaagtt gaaatcgaag taaaatataa aattgctgtg actgttatgg aactgcgatt
     6661 ttggctaaag gattgtgagt taccaatata atcatgtggt gcttgggaaa ctggtggaat
     6721 aacaggaaat gtaattagaa taaagaaaga tagaaggcga gtagcggatt ggtgtctgct
     6781 gctcactttt cgtttatggg gatatgtcgc aatacgactt ttgaagtgtt gtattgcaat
     6841 ctgttttcgg gtatttctcg ttggtatcat taccataaaa gcgaggtgaa ttccatgaaa
     6901 gcagagaaga aggaaatcaa tatacagatc ggaaaaaggt tgcaaaccgc cagagaaaac
     6961 agtggatata cgcaggaagt ttttgcagag acgctggatg taggggtaga gcattatcga
     7021 aaaatcgaaa gcggtgtcta tggcttacag ccggagaaaa tgctgatctt gtatgagaag
     7081 tacaggatcg agccgactta tctggttacg ggggatacaa atcataaggt tgatattgaa
     7141 ctgttccttg caaactgcag cagggaggaa cgggatgcat ttatagaccg catgcttgcg
     7201 tatatgagaa agctgatgac aggccgttaa agcagcacag tctccgggat gtatatttga
     7261 tcaatatatt ttgagaagga gacgatgtat gagggtagca atctgcgatg ataatcagca
     7321 ggacattgaa aggattagac gctatacatt gcgtatgatc gattatgcgg tggagtatgt
     7381 gttttatacc agaccggaag aattattgag ggaatgtgca gatgcggagc aaaagccgga
     7441 tatgtacatt cttgatattg agatgcctgg aatggacgga cttgcggtgg caaaacagat
     7501 ccgtgagaca gattccaaag cattgctggt gtttcttacc agctatacca aatacatgcc
     7561 aagtgtattt gaagttgtca catttgattt tattccaaaa ccaatctcag aagaaaggct
     7621 ccgtgtgctg tttgagaagg caggaaccta tctgaatctg accaatcaga gtttttcatt
     7681 tagttaccgc agggtgcggt acagtctgaa gtttgacgaa atcctgtatc tggaaaagcg
     7741 ggggcgtcag gcgattatcc acacaaagaa aatgaaatat cagtccaaca tgaatttgaa
     7801 tgaaatatgg gggaaactgg atgagcgcat gtttgccgcc gttcatggct cttttatcgt
     7861 taatttgaaa catgttcatt ccgtatccag cggcatggtc atgcttacag acggcacaga
     7921 gctgggagtg acaagagggt accggaagga gctgacgaaa aagcacatag cgtttgtgca
     7981 gggaggaatg tgacatggca ttatatgggg tgaggcttgt cataaatctt tttgacctct
     8041 gcatttaccg caggtattta gaggagttca ttggaaacag aaaaacttcc atggagtttt
     8101 ctgttcttct gctgatagtg tgcgagctga ttggaagtgc ggtgaaccag atggggataa
     8161 gctggctgaa ttttgtgacg atggttgcga ttctctgtgt atatgtctgc cagtatgagg
     8221 cagggattgt aagcaggctg attgcggttt tgctgtatat ggggattatg ggagttgcag
     8281 aaccgttagg atatttgttt aataaggcat tcatggaaaa ggtgttggac gataccacgg
     8341 tttcatatta ttttatcgtg ttttttatgg cacttttgaa agcaacaatt gtggaggtgt
     8401 tttgcagact gaaatctgga aaaagcattc gactatcagc aatgccaaaa gaaacgcaat
     8461 atatgttgac aatgatacct ttatgcagcc tgatcagttg ctttttactg atagaggttg
     8521 caaaagaatt aatctcggca cagatggtcg tgctgtgcat gtgcatcatc tttgtcatta
     8581 tcatcactaa ttatgtaatt tttctgatga ttgaaaagta tacgacagtg gaagaaaaac
     8641 agcacgaaga ggaaatgatc cagagggaaa tcttataccg gaacgaatac tatcaggaca
     8701 tggaacggta tcaggaacag atacaggaca tccggctggc agaagagatc atttattccg
     8761 caaatcctgt ggtgaatgcc atattaaaag taaaaagcgt aaaggcaaaa gagaaagaga
     8821 taccgatgca ggttacaacg ctgctccccc agagagtatc cgtggatatc ggggacatgg
     8881 gtgttctgta tgggaatctt ctggataatg cgatagaggc agcaatggca gtggaacagg
     8941 aaaaacggta tgttcatgta gaatcaaagt ttcaagaggg cagactgctt ttatccatta
     9001 agaacagcaa gccatccggg acaagttcct atcgacagac aagcaaaaaa gataaaataa
     9061 aacacggcag gggaatccgt tcagtgcgga aagtggcaga aaaatatggc ggggagcttc
     9121 tgttaaagga tcagggggaa cattttgagg cagcccttct gctcaatgga atcacaaaac
     9181 tggagtgaac ttgcaactta ttacagcaaa cctgcaactt gttacagata gattgatttt
     9241 tatatggaaa ctgttagagt gaaaatatca aaaaaaggag ggttttacta aaaatgaaga
     9301 aaagaaactg gatgtaccga ctgagcagca aatccatgag cgtgatggca gcactggcac
     9361 ttatggtgac aaccatggca acgaaccgtt cctgcatgtg gtatctggga caggacaaga
     9421 tgccagaaga ttccaaaaaa ctcagaaggt tttaagctat gacgagatgg ctcagccatc
     9481 gtatggttga gcggggaatc ataaaagagg aggagcagga attataccag tttggaatac
     9541 gcaatggtat gatcctgctt ctaaacgttg tgacggcact ggtcatcggg ctgctcacag
     9601 agcaactggc ggttgtggca gtgtttaccc tgtcttttat ggttcttcgc agctatactg
     9661 gtggatatca ctcagacagc aggattttct gctatcttgg ttccaatctg gtgctgctgg
     9721 ttccggttta tacacaggct gtgttttaca agacatcgtt ggcatggctg ctggcagtat
     9781 tgctggtgtc cgcagggatt atttttttac tcagtcccat gcacagcaag aaccgaaaac
     9841 tggataaaga ggaacaaaag cattttggca gaaaagcaag gctgattgca gcgttggaac
     9901 tggctgtgct tggcattttg tggcatgcag gccaggtact gtatgcttac gctgtttata
     9961 caggaatctg catcacggca ctgtttatgc ttataggaaa agcacagcta tggatacagt
    10021 cacataccga aaatagatag tcctttccga acaaacggaa gggacttttt ttctggaaaa
    10081 caggaaggat gacaatccaa gacggtaact tattacaggt accgtaagac ttattacact
    10141 tatattgaaa cgcactttct ttccaagtat agtaccgcaa aaaggcttag gagaagaaag
    10201 gcgtggcatg ttttggggaa ttcatgccgc accggattgc agggggcggc agaaagggaa
    10261 aagttcataa ggataacatc cgggtgcagt tttgcatgct ttattttgca tgggaacagc
    10321 accttttttt attgtctttt tccagtgaag taaaacccag aggccctcca gatgtccttc
    10381 atttcaaaaa aattacgaaa tggaggacat ttgaatgtca gaatggatca ggatcagagt
    10441 aaaggatttt tataaagatg cagttggtga gctggaatac acctatgtga ccagagaagt
    10501 ctacgaggca cttgtcgata cgttccgcaa agaagcccac gcacaggaaa tgcgggatat
    10561 cagacatacg accaaggacg gatatacaga gggagaaacg gaagatctgg tggagctgac
    10621 cggggaatcg gtagaggata cggtcatccg gcagatggaa atagaaaccc tgcagaaagc
    10681 aatgcagtca ctcaccccag tgcagagaga gcggctgcat ttttattttt ttgagggcat
    10741 gacataccgg cagattgcag cgaaagaagg ggtcggagag aagaacatcc gggagagcat
    10801 aaacggtgcg gtaaagaaaa taaaaaaata ttttgattaa taccccctca aaacgtgttt
    10861 ttctgtgagt accttatgag aggaactttt tctggacaga tggtctcttc cgggaatcct
    10921 ctcatgtctc gtgtgtggat acgacacagg cagacaaaac gcacattgaa aaatgccgga
    10981 gaggaatgca gggctccgag cgcaggatgg aatcacgcca tatcctgcca gccatatcca
    11041 gcagttcaga tacgttagcc gtttcatgag ccgtaaccgg ggcgcagtga cactcctgca
    11101 gcaatcgggc agatgttctt tctgccagcc atgctgtgaa aaagatcgca tctaaggagc
    11161 cgagcgggaa agccggggta cagcctgtct gtggtggaca ggcgcgaaga ggggaatggc
    11221 ctataatgat acaccttgag attagccagc acgcagtggt ggaggtgagc tacctgtgat
    11281 gtctgcctgt ccgagtggca gggaccaaag acagtctgga ctgactgccc atgaaatgcc
    11341 ggctttggga ttttttcttc tctgttttgg cggcgttttg gttccgggga gtagtgacga
    11401 atagggacag acacttttta tttatgaagt gaaggattat ggcagtaaga cttaattaca
    11461 gaaaccatgc ggcggagggg aacttccgcc gtattcttgt ggagttaaga aaagctgaaa
    11521 aatggggaat ggaggaaaac aggagatgaa gaaagaagat accgaaatga tgttaaggat
    11581 ttttgaaacg gagagggcag gatatgccta tctttatccg agtgatggag gggagcggaa
    11641 agaggactat atctcgacta cggcagaaaa tatcgcaaat tatatcggca gccacatgtt
    11701 tgaggctgaa aagatcgtca tcacagatat gtgtgacagg ctgatattag atacctgcgg
    11761 ctattttatc aatagctgtc cgaatcagga attctgcaag gaaatcaatc cgttcttaat
    11821 cccaatccag atgggagaaa aggacgcagg agaggtgctt tcagtcagca gggatgtatc
    11881 ggaacagtat ttccgggaag aagatgaggc tgcaaccatg gctgaaatcg ggatgatgta
    11941 aaggtgtttc ttctgggcaa aagtgtttgg cttgggagaa tgaatttaac gttcttaaat
    12001 tgcgggagga aaaagggaaa agatgatgga aggcggagcg aatgaggtgc ggtataagat
    12061 tgccgaattt ctcttaaaaa ggatgcatga agataagctg ttaaccgagg aagaatggga
    12121 aaaaatccgg gttttgaatg tcaagacttt ctccccggaa ttagcaaaag tatatctgta
    12181 ataacactgg atatataaag gactatgtgg tagtgtatgt tgctgacagg gagtgcaaac
    12241 ccttgaaaat actgggaaag gagaaaaaag catggcaaaa aaagtgactg tcataaaggc
    12301 agcaaaagcg cagaaacata cacaggaaga acgcaggctg aaagtgtgcg gatatgccag
    12361 agtcagtacc ggcagtcagg cacaggcaac ttcctatact gcacaggtcg agtactatac
    12421 ggaaaaaatc gagagcaacc ccctgtggga gtttgcaggg gtgtatgcgg atgaaggaat
    12481 cagcggaaca aacgtaaagc acagggatga gttccagatg atgatttcag actgtgagga
    12541 tgggaacatc gacctgatcc ttacgaaatc catcacaaga tttgcaagaa atacggtgga
    12601 atgcatccag accatccgaa agctgaagga gatcggcgtt ggaatctact ttgaaaaaga
    12661 gaatatcaac acgctgtcag aaaaaagcga gctgttcatt accatcctgg catcggtggc
    12721 gcagggggaa tcagaaaaca tctcaagcaa caaccgctgg gcgatacaga aacgctttca
    12781 ggatggaacc tatatcatat ccacgccagc gtatggctat ggaaaagacg aggatggaaa
    12841 tttagtcatc atagaatccg aggcagaaac cgtaaggtgg atttatgagt cttacttaaa
    12901 cggcatggga gtgtatgtga tagcaaaggc actgaaccag aaaggcattc caacaatccg
    12961 gggtgcagaa aagtggcagg acggggtgat acaggacatt ctgaaaaatc ccatttatga
    13021 gggagatatg cttcagcaga ggacatatac agaaacaagg ttcccatttg tccgcagggt
    13081 aaacaacgga cagagaaacc agtatctcat caaagacagc catccgccaa tcgtcacaca
    13141 tgaggaggca gaagcggtac gcaacctgat ggcataccgg gtggatgtac tgcacatgaa
    13201 caagagtgac tacaccaaaa gatacctgtt ttccggcaga atcatctgcg gagagtgcgg
    13261 aagaaccttc cggcggcaga aaatctacat cgggaaacca tatgaaaaaa tcatctggac
    13321 gtgcagcgga catgtggagg ataaagagcg ctgctgcctg aaagccatcc gggaggatgt
    13381 gctgcaccgg gcttttacag acatgtggaa caagctgtac accaatcagg gaacgatatt
    13441 agagccgctg ttaaaagagc tgacagaact tgtggcagca aggcaggaca gtgaggaaat
    13501 cagacaactg gataaggaaa tcaaagatat aagcgggcag agccaaatcc taaaccaagt
    13561 catgaggaaa ggatatatgg actctgctct ttttatggag agcagtagca agcttggctg
    13621 gcaactgacg gaatgcagga gaaaaaagac acttttgacc agaaagctga gaaggacaaa
    13681 agaaatcgtg cggaccgaac agcttatcca actgatcgca gaacaggacg gattaatgga
    13741 ggagtttgac gagcaactgt ttaaaatgac agcggagaag atcgtggtct ccaaagaaca
    13801 cgacatcacc ttctgcctgt acaacggact gaaactgacg gagaggggag gtggacagga
    13861 tgcagtggca catgccaatc ggctataaag ttgtggatgg aaaaatcacc atctgcgaag
    13921 agcagagaaa gattgtggaa cagatattta cagactatga cagcggagtg gcggcaggca
    13981 ggatcgccca gaacctgaaa gggagaaaaa tatgcaatgc aaaagggaaa gtgtcctgga
    14041 cccatgcatt cattggcagg atactggaaa acccaagcta ccttggcaca gaatactatc
    14101 cgcagctcat aggagaggaa ctgtttgaga gagtccagcg cagacgggaa aaggtgaggg
    14161 cagagcttgg aagggcagac caccggtccg gcagggatga gagaatcctc ttcggaggtg
    14221 tcatctggtg tgcagaatgc ggggcagtat gcagccatat ccagccgagc cacaaaaaag
    14281 agcgtggcgg cactgccaag tggaagtgca agagttatgt gattggcaga gcaaaaaact
    14341 gcaggaacag ttttattaca gacgggcagg caaagcaggt gtgtgtggaa gccatcaatg
    14401 cagtgatacg aaacaaaggc ctgctccggg tacaaaggca ggaggaaaag gtcagccctc
    14461 agtaccgggt tctggagcgg aacctgcagc ggatgaaaga agaacaggaa cgcacagaaa
    14521 cagacctgat gaaattgctc tatgaaaggg cagaggaacg ctaccggaca ctggaggtca
    14581 gggatgggga gttccggaca gaggaggtca aaaacatcct tgcagggaaa aaggaactgg
    14641 aaacatttga tgaaaattta tatagaaaaa taatcgcacg catctgggtg catggcggaa
    14701 acatggcaga agtggagctt atcaatggga gccgtgtcac agccgggtac aaggattagg
    14761 agggagagca gatggcagaa acagcaaaaa agatcagcat gatacctgcc aaggtgcagt
    14821 atgaccggaa tgtgaaactg tcagagaaga aaatgaaggt cgctgcctac tgccgtgtca
    14881 gtacggaact ggaagagcag gacagcagct atgaggcaca ggtggagtat tataccagca
    14941 agatatctga aaacgaaaac tggaaaaatg ccggcatcta tgcagatgac ggaaagagtg
    15001 gaacaaacac caaaaagagg gcagacttta atgccatgat acaggatgcc cttgccggaa
    15061 aaatcgacat gatccttaca aagtcggtca gcaggtttgc gaggaacacg gtagactcgc
    15121 tggtgaccat ccgaaaactg aaggaaaaga atgtggcggt ggtgttcgag aaagagggga
    15181 tcaatacact ggagggaacc ggcgaaatcc ttatcaccat cttaagcagc ctggcacagg
    15241 aggagagccg caacatcagt gagaacatcc gctggggagt cgtgaggaaa tttgaaaaag
    15301 gcaaggtcat cgtaaactgc acaaagttca tgggatacac caaaaacgag gatggtgacc
    15361 tggtcatcgt acccgaagag gcagagatcg taaagctgat cttccgcctt tatctggaag
    15421 gctacagtac cgggaagatc gcaaagcatc tggaagagca gggaatcaag accgccacag
    15481 ggcaggacaa atggcattcc acggtaatag acaaaatgct ccgcaatgaa aaatacatgg
    15541 gagatgcatt actgcagaaa acctatacgg tggatttcat gacaaaaaag aaagtcaaga
    15601 acactggaat cgtaccgcag tattatgtgg aagatgacca tgaggcaatc attccgaaag
    15661 agctgttcta cagggtacag gaagagatga tgcggagggc atccttatgc aaggcggctg
    15721 tcacccggaa gaagaaccag aaaagcaggt attcctccac ctatgcactg accggcatgc
    15781 tgatctgcgg aaaatgcgga caggagtaca ggagagtcac ctgggcgaga aacgggaaaa
    15841 agaaagtggt ctggagatgc agcaatcggc tgaccaacgg agtgaagaaa tgcggggaat
    15901 ccgagacact cgaagagaac gcattaaaca gggcggtgat ggaagccatc cacaggatca
    15961 caagtgatga tatggaattt atggaaaact tccggcagaa catcatccat gtcatcggga
    16021 actacagcac cgcaaaagag tctgaggaat acgaagaaaa gataaaagaa aagcaggaag
    16081 agatggtggc actgatcgcg gagaatgcaa agaccggctc ctacacaccg gagtttgatg
    16141 aacgctatcg caccatagca gaggaaatca atgccttaaa agaggcacag aaaacagcca
    16201 gaaacgagaa atggatggct gacagctatg aacagagaat ccaagatatc gaccattact
    16261 taagcacaag cacctgccag ataccggagt tcgacaatga ccttgtcaga cggctgatct
    16321 ccaccatcaa agtggaatcc agcgagaagc tgctgataca gttccagtca ggcattgtca
    16381 tggaacagga gattcgatat gagtaaggct gcggcaggaa tggcagcaag taaataggaa
    16441 acgttgttcc tgccagttta tggtaagaat aaaatgcccg atgatccggg cgttttattg
    16501 ttggcataaa ataggaaagg acagcagaaa gcatataacg gaaaatgagt aaaagaaagt
    16561 ggatataaaa aaagcacatg aagtaagtgt gcgacaggag gagaaaagcg tatgaattat
    16621 gagcaactga tagaagaact gagggaggaa atgttacagc ttgtaaacac gaaatgtgat
    16681 gcactgctcc agatgtaccg aagtggagaa atgaggacag acatgaaaga tacaatccgg
    16741 gaaagcagtc ttattacagt gtccccggca gaactgaaag ggaaaagacc gctggcagtc
    16801 cagttcgcgc cgggagaatg gatagagaca cctacatgga gaaaggtggc acaaagaatt
    16861 ttgcagacct ataatgaaca gccggatatc catgagcgtt ttatggaaat gtgtggaaaa
    16921 gtagccggac gctggaggac gatccttggc agttcaccgg aagaaatgga tgtaccgcta
    16981 aaggtggatg aggaacttta ttttgaggga aaatttgaca ccgaagcgat gttaaacatg
    17041 ttagagaaaa aagtgctgga accggcagga gttgattaca gcagcattaa aatccggtat
    17101 atgggaaaag ggcaggaagt agcaaaaagt ttagagcagg atgttttgga gcaggagggg
    17161 caggaacagc atgcaccggt gcagacaatg taaaaaatgg acggaatcaa gactccaagt
    17221 ctatgacagg tttggagttt ttcttatgtt ccttttccaa atgtaaaaat tgattgtata
    17281 aaagaaatgg gtaagttata atctcatctt tgacagttga ttagttaaaa aagtgccaca
    17341 atccctgtaa atacaagggg cgtggcactt ttatctgcat acacgaaata tagtaatgtt
    17401 ttatctccgc ttactttttt tctgaattcc tttcattttc cgttttgtta tgaattgata
    17461 gtccgttctg aatccgcagg tttcatggag atcatcagtg atttcctgac gttcatatac
    17521 cggcatgaag ccctgttctt ctatatccgt aaattttatg tcttttaaag tgtgaagtaa
    17581 ttgttctgtg gtataagtcc ctttcaagga gcggtttaat aaccggaaat gtaacagagc
    17641 aagaaagcag gtgaggaaat gagctttaat ccgatcttca cggtttaagt aaacgggtct
    17701 ggcttcaaag tctgttttca tagttctgaa acagtcttca atctgccatc ttccttcact
    17761 gacttttaag atatctgcaa cgtcatcatc aagcaggtct gtacataccg cataaagtcc
    17821 gtcatacatt tcttcttcag caatcttatc cgtatcgaga taatagtgga tcttagcttt
    17881 ttctccttcg ttggttacag ctaccttatt tacaaatctt gcaggatcat ttggattttt
    17941 acgctgtttt tttagagagc catttgcaac cattttttct gcccgacaga tctgctccgc
    18001 acggatggct ttctgataag cggcatattt aggggagacc agctatgaaa agtcaaccat
    18061 aaattagcaa aaaatttctt tttcatatcg gtggtaaaaa agggtaactt taatagagct
    18121 cccttagggt gctttttcaa aatctatcga tattggtata cagacctctt attcgaggtt
    18181 gaattctact tcgccagtga gcatcttcca gatgactctg acaagcttgc cggcacagtg
    18241 cccaagtgca ttgtagtgag accggccttc agccctcttg gcatcataat aagccttgaa
    18301 ggttgcgttg tttctgacaa cgttccaagc tgcatttaca agggcatatc gtaaaacacg
    18361 agagccacgt ttggacatcc ttgttgtctt agcctgaaag ttaccagact gataaacaga
    18421 aggatccaaa ccggcaaaag caagcagctt gttaggattg gagaaacggt gaatatcacc
    18481 tatttcacca agaatcattc caccattgat ataaccgata ccaggaatgg tcatgatgac
    18541 agaatcgttg aatttcatga tatccgtcat ctcagcttca atcttttcta attggctatc
    18601 cagtaactcg atttgttgaa tggtttgagt tatctgaata gatatagcgc tgtcgttagc
    18661 accgacagac ttctgtgcga gaactcttaa ttctttggcc tgttctttgg taaagtgtcc
    18721 gtgtgagttc actttgagca gatttgccag atgagtcata tgcatggaag caatctcttt
    18781 tggagaaggt gtttctttta ataaagcata gacagcgtgt tgatgcagac cggatttgaa
    18841 aaagtattga atctccggaa agacctgatc aacataggtt gtcagttgaa ttttcaatcg
    18901 ggtacgttgc tttatggttt tctgacggaa acgtcccaat gccttaagat ccatcatatc
    18961 gagatcgaag aagctgacga atctgaggtt gtcctgcatc ataagagttt tagcaatcac
    19021 gtaagtgtcg accttatctg tcttagtttt gcgaacgtta ttttttcgca tttgacaggt
    19081 tttgatgggg ttcaacacac acacttggta aagctcagta acaaggtatc gaacaaggtt
    19141 gtcaccgtag tgtgccgttg actcaagacc gatgatgagg ctgttcttat cgaatgattc
    19201 gagtttagag accagcagtt ggaagccatc agcgtcattt gtgaatttga acggctcaat
    19261 gattatttca ccgtcggaag aaatcgcagc ggcgaaatga ttaagtttgg caatatcaat
    19321 gcctacgtaa attttcat
//
