LOCUS       NZ_CP124548.1          22182 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP124548.1 Actinomyces israelii strain F0345 chromosome, complete
            genome.
ACCESSION   NZ_CP124548
VERSION     NZ_CP124548.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:17:25
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3591032
            Orig. end    :: 3613214
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22182
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[3601032:3603214]"
                     /cutoff="20000"
                     /detection_rule="((((goadsporin_like or PF00881 or
                     TIGR03605) and (YcaO or TIGR03882 or TIGR03604)) or
                     TIGR03603 or TIGR03602) and not cyanobactin_synth)"
                     /neighbourhood="10000"
                     /product="LAP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12182
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((((goadsporin_like or PF00881 or
                     TIGR03605) and (YcaO or TIGR03882 or TIGR03604)) or
                     TIGR03603 or TIGR03602) and not cyanobactin_synth)"
                     /neighbourhood="10000"
                     /product="LAP"
                     /protocluster_number="1"
     cand_cluster    1..22182
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((((goadsporin_like or PF00881 or
                     TIGR03605) and (YcaO or TIGR03882 or TIGR03604)) or
                     TIGR03603 or TIGR03602) and not cyanobactin_synth)"
                     /kind="single"
                     /product="LAP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22182
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="LAP"
                     /region_number="7"
                     /rules="((((goadsporin_like or PF00881 or TIGR03605) and
                     (YcaO or TIGR03882 or TIGR03604)) or TIGR03603 or
                     TIGR03602) and not cyanobactin_synth)"
                     /tool="antismash"
     CDS             complement(1002..1496)
                     /locus_tag="ctg1_2953"
                     /transl_table=11
                     /translation="MDIKLLRIDSRLVHGQVANNWAGSLGAEAILAVSDGAANDELRKT
                     LMLQTGGGKVKVHVLGVEKAARVYKNPKYASLKAVIVVETPADIVRLLDLGVEAKEVNV
                     GGMTFKQGTKALSQAVYISDEDAKAFQEIDKRGIAQYIQQVPSTGRSDLMEALRSKGFI
                     S"
     PFAM_domain     complement(1053..1490)
                     /aSDomain="PTSIIB_sorb"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03830.17"
                     /description="PTS system sorbose subfamily IIB component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2953_0243"
                     /evalue="2.90E-45"
                     /label="ctg1_2953"
                     /locus_tag="ctg1_2953"
                     /protein_end="148"
                     /protein_start="2"
                     /score="154.3"
                     /tool="antismash"
                     /translation="IKLLRIDSRLVHGQVANNWAGSLGAEAILAVSDGAANDELRKTLM
                     LQTGGGKVKVHVLGVEKAARVYKNPKYASLKAVIVVETPADIVRLLDLGVEAKEVNVGG
                     MTFKQGTKALSQAVYISDEDAKAFQEIDKRGIAQYIQQVPST"
     CDS             complement(1496..1933)
                     /locus_tag="ctg1_2954"
                     /transl_table=11
                     /translation="MVAVIVAAHGHLAEGLIASSAMIAGPQEDLVAVTFESSEGPDDLL
                     AKYAAAVEKSPSDQYLVLVDLLGGSPYNAAARFAAEREDADVVTGVNLPMLIEVLGRRL
                     TGGTLPELVETARTAGSGGVKVLSEIFTPTNTDSDDEGDEL"
     PFAM_domain     complement(1589..1924)
                     /aSDomain="EIIA-man"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03610.18"
                     /description="PTS system fructose IIA component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2954_0244"
                     /evalue="7.20E-25"
                     /label="ctg1_2954"
                     /locus_tag="ctg1_2954"
                     /protein_end="115"
                     /protein_start="3"
                     /score="87.5"
                     /tool="antismash"
                     /translation="VIVAAHGHLAEGLIASSAMIAGPQEDLVAVTFESSEGPDDLLAKY
                     AAAVEKSPSDQYLVLVDLLGGSPYNAAARFAAEREDADVVTGVNLPMLIEVLGRRLTGG
                     TLPELVET"
     aSDomain        complement(1592..1933)
                     /aSDomain="TIGR00824"
                     /aSTool="tigrfam"
                     /description="EIIA-man: PTS system,
                     mannose/fructose/sorbose family, IIA component"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2954_0038"
                     /evalue="2.60E-31"
                     /identifier="TIGR00824"
                     /label="ctg1_2954"
                     /locus_tag="ctg1_2954"
                     /protein_end="114"
                     /protein_start="0"
                     /score="106.1"
                     /tool="antismash"
                     /translation="MVAVIVAAHGHLAEGLIASSAMIAGPQEDLVAVTFESSEGPDDLL
                     AKYAAAVEKSPSDQYLVLVDLLGGSPYNAAARFAAEREDADVVTGVNLPMLIEVLGRRL
                     TGGTLPELVE"
     CDS             2253..3776
                     /locus_tag="ctg1_2955"
                     /transl_table=11
                     /translation="MSTPPTSTRSTPRTQSTPDPARRTRLLPRRSALRSFSALAALAST
                     GALTGCGSTPDKDRDDALAKIEWLPSEVDTESVSLDQQRATTAVTACNAVGATMLSTLL
                     RQATGSNALSCPVGITFILALLYAGAESVGEGVNAALGVKADAQAQSRDSTWSAVRQTL
                     QRFDVADVQQLRDFDPGTIPESPLIHVANNIMIVDEKTVVRQEYLDNAKRWYDSEIGRI
                     RNPDARAALDAWAALHTGGLIKESGIDITPDTRLVLQNALLFAARWAAPFKAEETEKGA
                     QFTLADGSSSTADLMTDTGVYPLVSGKGWRALRLHYTAGSDSPSSSSGTDSEAVAPGSG
                     SPSSSTAGSSAPDPGPGSASSNLAMDVILPDNVVSPADLPASTWGEATAALTAATAEQQ
                     VALKLPKLDLASGVMDLFPVLTAMGVDLGSLDHIAEGIDATQAAQQVRLIVDEEGTVAA
                     ALTEIGIETSAVDESDAVEFTVDHPYVLRIVDLASGVAIIEAAILNPAG"
     PFAM_domain     2526..3767
                     /aSDomain="Serpin"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00079.22"
                     /description="Serpin (serine protease inhibitor)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2955_0245"
                     /evalue="9.70E-42"
                     /label="ctg1_2955"
                     /locus_tag="ctg1_2955"
                     /protein_end="505"
                     /protein_start="91"
                     /score="143.7"
                     /tool="antismash"
                     /translation="CNAVGATMLSTLLRQATGSNALSCPVGITFILALLYAGAESVGEG
                     VNAALGVKADAQAQSRDSTWSAVRQTLQRFDVADVQQLRDFDPGTIPESPLIHVANNIM
                     IVDEKTVVRQEYLDNAKRWYDSEIGRIRNPDARAALDAWAALHTGGLIKESGIDITPDT
                     RLVLQNALLFAARWAAPFKAEETEKGAQFTLADGSSSTADLMTDTGVYPLVSGKGWRAL
                     RLHYTAGSDSPSSSSGTDSEAVAPGSGSPSSSTAGSSAPDPGPGSASSNLAMDVILPDN
                     VVSPADLPASTWGEATAALTAATAEQQVALKLPKLDLASGVMDLFPVLTAMGVDLGSLD
                     HIAEGIDATQAAQQVRLIVDEEGTVAAALTEIGIETSAVDESDAVEFTVDHPYVLRIVD
                     LASGVAIIEAAILNP"
     CDS             complement(3840..4289)
                     /locus_tag="ctg1_2956"
                     /transl_table=11
                     /translation="MTVEIIAESTPELIEAMERLIPQLSRSAPALTAEQCEAFVAQEGV
                     YLFVFRPDEPAADGARPILGMLTLATFSIPTGLRAWVEDVVVDSATRGQGAGRALVEAA
                     VAHAGRLGARTVDLTSRPSREAANRLYRRCGFELRETNVYRYSGK"
     PFAM_domain     complement(3882..4187)
                     /aSDomain="Acetyltransf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00583.27"
                     /description="Acetyltransferase (GNAT) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2956_0246"
                     /evalue="3.40E-14"
                     /label="ctg1_2956"
                     /locus_tag="ctg1_2956"
                     /protein_end="136"
                     /protein_start="34"
                     /score="53.2"
                     /tool="antismash"
                     /translation="QCEAFVAQEGVYLFVFRPDEPAADGARPILGMLTLATFSIPTGLR
                     AWVEDVVVDSATRGQGAGRALVEAAVAHAGRLGARTVDLTSRPSREAANRLYRRCGF"
     CDS             4546..5985
                     /locus_tag="ctg1_2957"
                     /transl_table=11
                     /translation="MSSDLSGAVPTGAAAACDAIGARMLAGRLHEGGAGSTISENSEAG
                     RGSHDGAADHRNVLACPVGLALALAVLRAGAADAGTDAALGIDSAPGTDAAPALVADGA
                     PRVGVGTPDSTGPRAPGDSASPLPRDLVWSAVQRALRRFDVAGPEQLRSFNPDAIPETP
                     LVHIANNILVVGEHVVRQDYLEAAKHWYDAEISRTPLAEAKTALDAWADLHTGGLIKQS
                     AIVLRPDTVLVLQNALLFAARWERRFTKASTIEKQPFTRADGSTSRADLMTSTRPYTLV
                     AGPGWRALRLPYNGGGATGGPTLAMDVILPNRVISPANLPASTWGEATRLLTAAQAEDR
                     ATRVRLRLPRLDLSSQPTDLTGVVESLGVPLGSQDHIGPNVSVSQVVQQVRLTVAEEGT
                     VAAALTEITARSGALAGWEDDFVVDHPYVLRIADQASGIALIEAAVLDPAAGTRPRCPV
                     LVEGASRLRARFTRRRRGPSR"
     PFAM_domain     4705..5889
                     /aSDomain="Serpin"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00079.22"
                     /description="Serpin (serine protease inhibitor)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2957_0247"
                     /evalue="1.70E-37"
                     /label="ctg1_2957"
                     /locus_tag="ctg1_2957"
                     /protein_end="448"
                     /protein_start="53"
                     /score="129.7"
                     /tool="antismash"
                     /translation="DHRNVLACPVGLALALAVLRAGAADAGTDAALGIDSAPGTDAAPA
                     LVADGAPRVGVGTPDSTGPRAPGDSASPLPRDLVWSAVQRALRRFDVAGPEQLRSFNPD
                     AIPETPLVHIANNILVVGEHVVRQDYLEAAKHWYDAEISRTPLAEAKTALDAWADLHTG
                     GLIKQSAIVLRPDTVLVLQNALLFAARWERRFTKASTIEKQPFTRADGSTSRADLMTST
                     RPYTLVAGPGWRALRLPYNGGGATGGPTLAMDVILPNRVISPANLPASTWGEATRLLTA
                     AQAEDRATRVRLRLPRLDLSSQPTDLTGVVESLGVPLGSQDHIGPNVSVSQVVQQVRLT
                     VAEEGTVAAALTEITARSGALAGWEDDFVVDHPYVLRIADQASGIALIEAAVLDP"
     CDS             complement(5954..6748)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1179:hydrolase (Score: 75.4; E-value: 8.5e-23)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2958"
                     /transl_table=11
                     /translation="MRKLLSTDIDGTLLFNAAISQDDLDAMTRWRDAGNLLVPNTGRSV
                     AALHSALSGSDLAFDYSVLYTGAALADGGYDVLEARTLPDGLAEEVLDLLEGETGVTVF
                     ATTLEGDLQLYDSIGSDTALLTLFSRASRADLAGRTVVGVPLRIADPALMAHMQAEVAR
                     RWGDVAVGFHNQNFLDIVPAGSSKGAGLTVLVERLAADDGPCRGERIETWSVGDSWNDI
                     SMHETADHAVAMNGSPPEVLAVCERTTTSVASLIDSVLASSE"
     PFAM_domain     complement(5990..6730)
                     /aSDomain="Hydrolase_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08282.14"
                     /description="haloacid dehalogenase-like hydrolase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2958_0248"
                     /evalue="2.70E-20"
                     /label="ctg1_2958"
                     /locus_tag="ctg1_2958"
                     /protein_end="253"
                     /protein_start="6"
                     /score="73.3"
                     /tool="antismash"
                     /translation="TDIDGTLLFNAAISQDDLDAMTRWRDAGNLLVPNTGRSVAALHSA
                     LSGSDLAFDYSVLYTGAALADGGYDVLEARTLPDGLAEEVLDLLEGETGVTVFATTLEG
                     DLQLYDSIGSDTALLTLFSRASRADLAGRTVVGVPLRIADPALMAHMQAEVARRWGDVA
                     VGFHNQNFLDIVPAGSSKGAGLTVLVERLAADDGPCRGERIETWSVGDSWNDISMHETA
                     DHAVAMNGSPPEVLAVCERTTTSVA"
     aSDomain        complement(6047..6739)
                     /aSDomain="TIGR01484"
                     /aSTool="tigrfam"
                     /description="HAD-SF-IIB: HAD hydrolase, family IIB"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2958_0039"
                     /evalue="1.60E-14"
                     /identifier="TIGR01484"
                     /label="ctg1_2958"
                     /locus_tag="ctg1_2958"
                     /protein_end="234"
                     /protein_start="3"
                     /score="52.4"
                     /tool="antismash"
                     /translation="LLSTDIDGTLLFNAAISQDDLDAMTRWRDAGNLLVPNTGRSVAAL
                     HSALSGSDLAFDYSVLYTGAALADGGYDVLEARTLPDGLAEEVLDLLEGETGVTVFATT
                     LEGDLQLYDSIGSDTALLTLFSRASRADLAGRTVVGVPLRIADPALMAHMQAEVARRWG
                     DVAVGFHNQNFLDIVPAGSSKGAGLTVLVERLAADDGPCRGERIETWSVGDSWNDISMH
                     ETADHAVAM"
     CDS             6984..7880
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 176.8; E-value:
                     9.5e-54)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_2959"
                     /transl_table=11
                     /translation="MSLNFHTPVRLTDVSRDFGPVKALSNVTLSIPAGGTVGLLGPNGS
                     GKTTMLSLIAGLREPTSGTVELFGADPRDRASRERLGVTPQQSGIVKEMKVLSMTRFIA
                     GHYADHEDAETLLEKFGIGQLAGKRIGGLSGGQQRLLSVALAFAGRPRLVLLDEPSTGL
                     DTMARNHLWDAIRRGARSGITILLTSHYLEEVQELSDRIIIIREGRIVADGSTEKIIRN
                     AASTIVRVTTGDDRALSLPGVTAAHRKGAVVELSVANPSTVLKSLGRAGIEYSDIDIIK
                     PTLEDAFTHLAVEEQTS"
     PFAM_domain     7053..7463
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2959_0249"
                     /evalue="7.00E-29"
                     /label="ctg1_2959"
                     /locus_tag="ctg1_2959"
                     /protein_end="160"
                     /protein_start="23"
                     /score="101.2"
                     /tool="antismash"
                     /translation="LSNVTLSIPAGGTVGLLGPNGSGKTTMLSLIAGLREPTSGTVELF
                     GADPRDRASRERLGVTPQQSGIVKEMKVLSMTRFIAGHYADHEDAETLLEKFGIGQLAG
                     KRIGGLSGGQQRLLSVALAFAGRPRLVLLDEPS"
     CDS             7877..8662
                     /locus_tag="ctg1_2960"
                     /transl_table=11
                     /translation="MTTARIRPEVSNILVPDSRLAWEWTRFEMASWLREPAAVVLNMAY
                     PLIMLGFFLVSTDIRTDSAAAISLLGYLSLVGVLMVCLNFPANGIPEARESDFYAFSRT
                     LPIGAAPRLIAWTAAPIACGLISAASTFIIATLVSAAEPSVMDFAIIIGVSLVLAVPIT
                     LLGLALGFILPKKTSLAVSLTIAFSMILFGGISGIPLPSIVETISHALPSGAAGHIIAS
                     HLNASDFDWRNIVVLIAWAVIGILAVFLLYRRDEGRRFR"
     CDS             8875..9987
                     /locus_tag="ctg1_2961"
                     /transl_table=11
                     /translation="MTLHPRRPQRLATGHLLFTELSRKCHHMNSIPPNPMIQPWITAAT
                     EDNTVVIRHADRAVVFTGPGAKALMPELIAKLDGTSQVDAIINSFPAEKQAAISSAIDL
                     LAHHNLLIEGTALTHTKDTPAPGLRNAASLAELLSPAITIDEIASRLSATHLHILTDLS
                     NISHLKNILVESGFGFVETFPLSAVTEVERSLTQNSVVVVAPKLSSARELRQMNDIALE
                     IGCRWTHILPYDGSYAIVGPLYIPGETGCYRCLQLRRRSTIEAADQQRIVDDDPDSILP
                     TPLDEWTSPGQEVALWGLFAHLLSIECLRLYWAPAPLAGHIHTMEWKGNTVNTVRHRLF
                     RVPRCPSCGPTDLGVPQPWFEAPATAAKKN"
     misc_feature    8905..8907
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    9274..9276
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    9349..9351
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        9574..9966
                     /aSDomain="TIGR03882"
                     /aSTool="tigrfam"
                     /description="cyclo_dehyd_2: bacteriocin biosynthesis
                     cyclodehydratase domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2961_0040"
                     /evalue="3.80E-14"
                     /identifier="TIGR03882"
                     /label="ctg1_2961"
                     /locus_tag="ctg1_2961"
                     /protein_end="364"
                     /protein_start="233"
                     /score="51.2"
                     /tool="antismash"
                     /translation="DGSYAIVGPLYIPGETGCYRCLQLRRRSTIEAADQQRIVDDDPDS
                     ILPTPLDEWTSPGQEVALWGLFAHLLSIECLRLYWAPAPLAGHIHTMEWKGNTVNTVRH
                     RLFRVPRCPSCGPTDLGVPQPWFEAPA"
     misc_feature    9643..9645
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             10001..11356
                     /gene_functions="biosynthetic (rule-based-clusters) LAP:
                     YcaO"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2962"
                     /sec_met_domain="YcaO (E-value: 8.8e-62, bitscore: 207.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINTAQKTPRFSERWNDRTASTESLLHLGSEHFGVAPIKFEITHS
                     SNEVRSHYIGVRSAAADEIIGTPVNHSNGGGSFSREQARIAGIAETVERYSAAYIPRTG
                     LRTCSYNNLNGPALHPSDFALFAPHQYEQPAFPYIPFTAETVTTWTQGLSLRTGLPTYV
                     PAQLVYLNRHLDPDSRIGYATSNGLACGPDYTEAAISALFECAERDAVMITWNAGLAMP
                     RIDLNSNLWVRKIIRRHFKPTWMNFAALDLTPINGIPTSLAVVWSNNPETQLLSVGAAS
                     RSTLAEACVEALLEAFHCTAYCRSLIRDNGSIDTSDNLDKKVVSLEDHVRFYGSDEHAK
                     LAEFLLGSSQQIDLQSTPNLDHSSPRQLLEELVRTLDGDIDCTIVDATSPDLQELDLAV
                     VKAVCPQFIPLGVGWRDRYIGGDRILDVPQKIGLSDHQLAYSELTPYPHPFP"
     PFAM_domain     10223..11221
                     /aSDomain="YcaO"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02624.18"
                     /description="YcaO cyclodehydratase, ATP-ad Mg2+-binding"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2962_0250"
                     /evalue="5.10E-58"
                     /label="ctg1_2962"
                     /locus_tag="ctg1_2962"
                     /protein_end="407"
                     /protein_start="74"
                     /score="197.0"
                     /tool="antismash"
                     /translation="GGSFSREQARIAGIAETVERYSAAYIPRTGLRTCSYNNLNGPALH
                     PSDFALFAPHQYEQPAFPYIPFTAETVTTWTQGLSLRTGLPTYVPAQLVYLNRHLDPDS
                     RIGYATSNGLACGPDYTEAAISALFECAERDAVMITWNAGLAMPRIDLNSNLWVRKIIR
                     RHFKPTWMNFAALDLTPINGIPTSLAVVWSNNPETQLLSVGAASRSTLAEACVEALLEA
                     FHCTAYCRSLIRDNGSIDTSDNLDKKVVSLEDHVRFYGSDEHAKLAEFLLGSSQQIDLQ
                     STPNLDHSSPRQLLEELVRTLDGDIDCTIVDATSPDLQELDLAVVKAVCPQF"
     aSDomain        10223..11353
                     /aSDomain="TIGR03604"
                     /aSTool="tigrfam"
                     /description="TOMM_cyclo_SagD: thiazole/oxazole-forming
                     peptide maturase, SagD family component"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2962_0041"
                     /evalue="5.30E-84"
                     /identifier="TIGR03604"
                     /label="ctg1_2962"
                     /locus_tag="ctg1_2962"
                     /protein_end="451"
                     /protein_start="74"
                     /score="280.2"
                     /tool="antismash"
                     /translation="GGSFSREQARIAGIAETVERYSAAYIPRTGLRTCSYNNLNGPALH
                     PSDFALFAPHQYEQPAFPYIPFTAETVTTWTQGLSLRTGLPTYVPAQLVYLNRHLDPDS
                     RIGYATSNGLACGPDYTEAAISALFECAERDAVMITWNAGLAMPRIDLNSNLWVRKIIR
                     RHFKPTWMNFAALDLTPINGIPTSLAVVWSNNPETQLLSVGAASRSTLAEACVEALLEA
                     FHCTAYCRSLIRDNGSIDTSDNLDKKVVSLEDHVRFYGSDEHAKLAEFLLGSSQQIDLQ
                     STPNLDHSSPRQLLEELVRTLDGDIDCTIVDATSPDLQELDLAVVKAVCPQFIPLGVGW
                     RDRYIGGDRILDVPQKIGLSDHQLAYSELTPYPHPFP"
     CDS             11373..12182
                     /gene_functions="biosynthetic (rule-based-clusters) LAP:
                     PF00881"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2963"
                     /sec_met_domain="PF00881 (E-value: 3.8e-21, bitscore: 73.5,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VTTPNTLEIIQPIEPGLFDPAENFIEASKLHRHLLEAEVPGIREL
                     TRSPALLDATGRATNPYPQRTPILLPDPASFPQEASLSDVLQERRSPRGFSSSPALSLD
                     KIGWLCWATDGNTGEIAPNRYGRTAPSGGALYPRDLYVTTIAGDVEAGLYHYNPYLHHL
                     EFVNSTTPHDVAGTTAQPEALAQASAVLLLMASFWRNRMKYNQRGVRFALTESGHVAQN
                     ALLAAVALGLSALPIGGYFDEELNTMLGADGLHEEVLYAIFLGSPLS"
     PFAM_domain     11631..12167
                     /aSDomain="Nitroreductase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00881.26"
                     /description="Nitroreductase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2963_0251"
                     /evalue="6.30E-20"
                     /label="ctg1_2963"
                     /locus_tag="ctg1_2963"
                     /protein_end="265"
                     /protein_start="86"
                     /score="72.0"
                     /tool="antismash"
                     /translation="QERRSPRGFSSSPALSLDKIGWLCWATDGNTGEIAPNRYGRTAPS
                     GGALYPRDLYVTTIAGDVEAGLYHYNPYLHHLEFVNSTTPHDVAGTTAQPEALAQASAV
                     LLLMASFWRNRMKYNQRGVRFALTESGHVAQNALLAAVALGLSALPIGGYFDEELNTML
                     GADGLHEEVLYAIFLG"
     aSDomain        11742..12167
                     /aSDomain="TIGR03605"
                     /aSTool="tigrfam"
                     /description="antibiot_sagB: SagB-type dehydrogenase
                     domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2963_0042"
                     /evalue="3.70E-33"
                     /identifier="TIGR03605"
                     /label="ctg1_2963"
                     /locus_tag="ctg1_2963"
                     /protein_end="265"
                     /protein_start="123"
                     /score="112.4"
                     /tool="antismash"
                     /translation="RYGRTAPSGGALYPRDLYVTTIAGDVEAGLYHYNPYLHHLEFVNS
                     TTPHDVAGTTAQPEALAQASAVLLLMASFWRNRMKYNQRGVRFALTESGHVAQNALLAA
                     VALGLSALPIGGYFDEELNTMLGADGLHEEVLYAIFLG"
     misc_feature    12042..12044
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    12060..12062
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             12216..12884
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2964"
                     /sec_met_domain="Abi (E-value: 5.9e-13, bitscore: 46.7,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEFMSGSLIFLGWWATWTTYIKYLRRTSQLHRFHSGIYDLCTLA
                     YALLALILSAAHITPFTLPQLRSGPIDYLIAAASGIALWSLQRIYLWHARHRTNSDCAL
                     GHYPVRRPYLLPLTAATEEILFRGCLLYGLIFLGVPPAGAILATGMLFGSLHAFQYGLY
                     GVVLHTVTGIAFGILAVRFGLGAAVVAHVIFNAMVLLTARGPARSPTTERAGHGRPAGD
                     "
     misc_feature    12306..12308
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    12360..12362
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     PFAM_domain     12564..12806
                     /aSDomain="Rce1-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02517.18"
                     /description="Type II CAAX prenyl endopeptidase Rce1-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2964_0252"
                     /evalue="6.20E-12"
                     /label="ctg1_2964"
                     /locus_tag="ctg1_2964"
                     /protein_end="197"
                     /protein_start="116"
                     /score="45.8"
                     /tool="antismash"
                     /translation="LTAATEEILFRGCLLYGLIFLGVPPAGAILATGMLFGSLHAFQYG
                     LYGVVLHTVTGIAFGILAVRFGLGAAVVAHVIFNAM"
     CDS             12920..13546
                     /locus_tag="ctg1_2965"
                     /transl_table=11
                     /translation="MALDHRDSAAEELRRIEDYRKSFRQSTRFDDRFACRMLAVTYLLG
                     FGGQYLAMILFPSFADKAGTVLMSVGSCAVFVVFRHSLRQHAGISGRAIRKSIYFGSAW
                     LVGMAVVSAVIALIVARLPGLDVIGVTRIVYAVACVLTGFMYIIGGILFHDRSELSLGG
                     WLIVVSVFSALLGMPLMLLSIAVLSALGFLGLAFVRSRADQRAAS"
     misc_feature    12926..12928
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    13373..13375
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             13543..13854
                     /locus_tag="ctg1_2966"
                     /transl_table=11
                     /translation="MTQKQIDDLIHAPTRLRIMAALVELGPDSEITFPRLQTLLNMTPG
                     NLSSHLKRLEGADYLAMSRSFTPRGVAKTTVRVTDTGIAAFDAYVASLKSIIGAPLEA"
     PFAM_domain     13585..13833
                     /aSDomain="HTH_34"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13601.8"
                     /description="Winged helix DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2966_0253"
                     /evalue="1.10E-16"
                     /label="ctg1_2966"
                     /locus_tag="ctg1_2966"
                     /protein_end="97"
                     /protein_start="14"
                     /score="60.8"
                     /tool="antismash"
                     /translation="RLRIMAALVELGPDSEITFPRLQTLLNMTPGNLSSHLKRLEGADY
                     LAMSRSFTPRGVAKTTVRVTDTGIAAFDAYVASLKSII"
     CDS             complement(13956..16235)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294:Nitrilase/cyanide hydratase and apolipoprotein
                     (Score: 61; E-value: 1.9e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2967"
                     /transl_table=11
                     /translation="MHQDAPTPPPATGRPAIEFRSAYDQGFARVAAVTLPVALANPAAN
                     ATAIIEQARTLSDDGVCLAAFPELSLTGYSIDDLLLGDVLLDEVLAAIETIRAASAGLL
                     PAIVVGAPLREGNRLYNCAVVIQGGAVRGVVPKSYLPTYREFYEKRHFADGADGRSAAA
                     RRISLPGVRDGAGEGGAVGHRDGAGATPAVGNREGGAVVPFGPNLLFEVADVPGLTFHV
                     EVCEDMWVPVPPSSLAALAGATVLVNLSGSPITVGRAEDRKLLARASSSRGLAAYVFAA
                     AGQGESSTDLAWDGQTFIYENGDLLGETERFPDGPRATVIDVDIEGLRAERLRQGSFDD
                     NRAALALGGPGRPGRGHPGPDGAPAPGAADAVGPGRFRTVRIGRRTLRAPRTDIGLRRA
                     VDRFPFVPDDPARLAQDCYEAYSIQVAALVQRLRAIGLPRIVIGVSGGLDSTHALIVAA
                     RAVDRLGLGREHVHAITMPGFATSAETRRNALALARSLGCHVEELDIRPAAEQMLAAMD
                     HPYGRGERGREVYDVTFENVQAGLRTDFLFRIAGRRGGIVLGTGDLSELALGWCTFGVG
                     DQMAHYGVNAGIPKTLIQHLIRWVVSERIFSDDVGRVLLAVLGTEISPELVPADDGEPI
                     QSTQARIGPYALQDFTLWHVLRRGSRPSRIAFLAEKAWADAGEGRWPVGLPEEERVAYD
                     LAAIRRWELLFLRRFFSNQFKRSTLPNGPKVVAGGSLSPRGDWRMPSDAGAAAWIAELE
                     RNVPPA"
     PFAM_domain     complement(14436..14963)
                     /aSDomain="NAD_synthase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02540.19"
                     /description="NAD synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2967_0255"
                     /evalue="6.90E-24"
                     /label="ctg1_2967"
                     /locus_tag="ctg1_2967"
                     /protein_end="600"
                     /protein_start="424"
                     /score="84.4"
                     /tool="antismash"
                     /translation="VAALVQRLRAIGLPRIVIGVSGGLDSTHALIVAARAVDRLGLGRE
                     HVHAITMPGFATSAETRRNALALARSLGCHVEELDIRPAAEQMLAAMDHPYGRGERGRE
                     VYDVTFENVQAGLRTDFLFRIAGRRGGIVLGTGDLSELALGWCTFGVGDQMAHYGVNAG
                     IPKTLIQHLIRWV"
     PFAM_domain     complement(15264..16151)
                     /aSDomain="CN_hydrolase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00795.24"
                     /description="Carbon-nitrogen hydrolase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2967_0254"
                     /evalue="2.70E-12"
                     /label="ctg1_2967"
                     /locus_tag="ctg1_2967"
                     /protein_end="324"
                     /protein_start="28"
                     /score="46.7"
                     /tool="antismash"
                     /translation="RVAAVTLPVALANPAANATAIIEQARTLSDDGVCLAAFPELSLTG
                     YSIDDLLLGDVLLDEVLAAIETIRAASAGLLPAIVVGAPLREGNRLYNCAVVIQGGAVR
                     GVVPKSYLPTYREFYEKRHFADGADGRSAAARRISLPGVRDGAGEGGAVGHRDGAGATP
                     AVGNREGGAVVPFGPNLLFEVADVPGLTFHVEVCEDMWVPVPPSSLAALAGATVLVNLS
                     GSPITVGRAEDRKLLARASSSRGLAAYVFAAAGQGESSTDLAWDGQTFIYENGDLLGET
                     ERFPDGPRATVIDVD"
     CDS             complement(16712..17422)
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 107.1; E-value: 2.4e-32)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2968"
                     /transl_table=11
                     /translation="MNSIDSASPGDYPSEIEEADRRKPGRPRAGGEDKRERILNEAIAL
                     FGAHGYAGTSLADIATASDISKAGLLHHFSSKEALFARVLARRDQDDFVGVMGGGAIED
                     PWELLDAFVTLVAHNSAHRDLVAIYAATAVSVLDAEHPAHRWFASHLAGSVRMIEEALE
                     RGKETGTVRPEAPSRMIARSVVALSDGLQIQWLCSTTPDSAADQCLATSMEPEVRMFVD
                     GLRERWRIDADARG"
     PFAM_domain     complement(17171..17311)
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00440.25"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2968_0256"
                     /evalue="4.00E-15"
                     /label="ctg1_2968"
                     /locus_tag="ctg1_2968"
                     /protein_end="84"
                     /protein_start="37"
                     /score="55.4"
                     /tool="antismash"
                     /translation="ILNEAIALFGAHGYAGTSLADIATASDISKAGLLHHFSSKEALFA
                     RV"
     CDS             complement(18498..21212)
                     /gene_functions="other (smcogs) SMCOG1223:ATPase (Score:
                     1056.9; E-value: 0)"
                     /gene_kind="other"
                     /locus_tag="ctg1_2969"
                     /transl_table=11
                     /translation="MDTNYTTRSQEAISGAMQAAAAAGNPQIDTLHLLAELLGQEDGVA
                     VGLLAAVNPDAGARQAIGAATRRALTQLPTSSGSSVSQPQPSRGLLAALEAASAEAKSL
                     GDEYISTEHLLIGIAAGKPSSDAAARILAEAGATAAALREALPKVRGSARVTSPNPEGT
                     YKSLEKYGTDLTEAAREGKLDPVIGRDAEIRRVVQVLSRRTKNNPVLIGEPGVGKTAVV
                     EGLAQRIVAGDVPESLRGKRLIALDLAGMVAGAKYRGEFEERLKAVLKEIKDSDGEVIT
                     FIDELHTVVGAGGGSEGAMDAGNMLKPMLARGELRLVGATTLDEYRENVEKDPALERRF
                     QQVFVGEPSVADTVAILRGIAPKYEAHHQVTISDGALVAAASLSDRYITGRQLPDKAID
                     LIDEAASRLRMELDSSPVEIDELQRRVDRMRMEESYLADSIEEEGSSADPDAADRLERL
                     RAELADASERLTALNARWEAEKAGHNRVGELRAALDDLRTRADLAEREGRFEEAGRLRY
                     GEMPSLEAQIRDMEAAQAAADAAVVGPDGVEREPGTAPEPMIAEKVGPTEIAEVISSWT
                     GIPVGKLMAGEQRKLLEMESVIGERLIGQKAAVTAVADAVRRSRAGVSDPDRPTGSFLF
                     LGPTGVGKTELAKALADFLFDDERAMVRIDMSEYSEKHSVARLVGAPPGYVGYEEGGQL
                     TEAVRRRPYSVVLLDEIEKAHPEVFDILLQVLDDGRLTDGQGRTVDFRNVILVLTSNLG
                     SQFLIDPLLSPEEKRKEVMAQVRASFKPEFLNRLDDTLVFDPLSKEELGRIVEIQLAKM
                     QERLAGHRLTLSVTDAARAWLADEGYDPAYGARPLRRLVQREIGDELARMILAGEVLDG
                     QEVVVDVSPDGVLAGLALTARGEAWAPSATSAV"
     PFAM_domain     complement(18585..18827)
                     /aSDomain="ClpB_D2-small"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10431.11"
                     /description="C-terminal, D2-small domain, of ClpB protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2969_0262"
                     /evalue="1.50E-28"
                     /label="ctg1_2969"
                     /locus_tag="ctg1_2969"
                     /protein_end="876"
                     /protein_start="795"
                     /score="98.7"
                     /tool="antismash"
                     /translation="LSKEELGRIVEIQLAKMQERLAGHRLTLSVTDAARAWLADEGYDP
                     AYGARPLRRLVQREIGDELARMILAGEVLDGQEVVV"
     PFAM_domain     complement(18846..19331)
                     /aSDomain="AAA_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07724.16"
                     /description="AAA domain (Cdc48 subfamily)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2969_0261"
                     /evalue="6.70E-53"
                     /label="ctg1_2969"
                     /locus_tag="ctg1_2969"
                     /protein_end="789"
                     /protein_start="627"
                     /score="179.4"
                     /tool="antismash"
                     /translation="RPTGSFLFLGPTGVGKTELAKALADFLFDDERAMVRIDMSEYSEK
                     HSVARLVGAPPGYVGYEEGGQLTEAVRRRPYSVVLLDEIEKAHPEVFDILLQVLDDGRL
                     TDGQGRTVDFRNVILVLTSNLGSQFLIDPLLSPEEKRKEVMAQVRASFKPEFLNRLDD"
     PFAM_domain     complement(19887..20168)
                     /aSDomain="AAA_lid_9"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17871.3"
                     /description="AAA lid domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2969_0260"
                     /evalue="2.00E-33"
                     /label="ctg1_2969"
                     /locus_tag="ctg1_2969"
                     /protein_end="442"
                     /protein_start="348"
                     /score="114.5"
                     /tool="antismash"
                     /translation="SVADTVAILRGIAPKYEAHHQVTISDGALVAAASLSDRYITGRQL
                     PDKAIDLIDEAASRLRMELDSSPVEIDELQRRVDRMRMEESYLADSIEE"
     PFAM_domain     complement(20184..20588)
                     /aSDomain="AAA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00004.31"
                     /description="ATPase family associated with various
                     cellular activities (AAA)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2969_0259"
                     /evalue="4.30E-12"
                     /label="ctg1_2969"
                     /locus_tag="ctg1_2969"
                     /protein_end="343"
                     /protein_start="208"
                     /score="46.7"
                     /tool="antismash"
                     /translation="VLIGEPGVGKTAVVEGLAQRIVAGDVPESLRGKRLIALDLAGMVA
                     GAKYRGEFEERLKAVLKEIKDSDGEVITFIDELHTVVGAGGGSEGAMDAGNMLKPMLAR
                     GELRLVGATTLDEYRENVEKDPALERRFQQV"
     PFAM_domain     complement(20760..20924)
                     /aSDomain="Clp_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02861.22"
                     /description="Clp amino terminal domain, pathogenicity
                     island component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2969_0258"
                     /evalue="2.80E-11"
                     /label="ctg1_2969"
                     /locus_tag="ctg1_2969"
                     /protein_end="151"
                     /protein_start="96"
                     /score="43.4"
                     /tool="antismash"
                     /translation="ASAEAKSLGDEYISTEHLLIGIAAGKPSSDAAARILAEAGATAAA
                     LREALPKVRG"
     PFAM_domain     complement(21027..21164)
                     /aSDomain="Clp_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02861.22"
                     /description="Clp amino terminal domain, pathogenicity
                     island component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2969_0257"
                     /evalue="5.60E-05"
                     /label="ctg1_2969"
                     /locus_tag="ctg1_2969"
                     /protein_end="62"
                     /protein_start="16"
                     /score="23.3"
                     /tool="antismash"
                     /translation="MQAAAAAGNPQIDTLHLLAELLGQEDGVAVGLLAAVNPDAGARQA
                     I"
ORIGIN
        1 gccaccgccg cccgcggcga ccggctgcgg cagccgcgta gcctcgtgga actcggggtt
       61 gagctggacg tagatgaagg cgaggcaagc gccgagaatg cccagggcca cgagggtaat
      121 tccctccttc agggtcgtca tgaaggtggc gacaacgaat ccgatgaaga agaacggcat
      181 gagcttgcgc gccttcatca tattaatcac catggcataa ccgacgacga caataaaacc
      241 gccggcgatc tgcaacccgt tggtaatgac gtccggaatg gcctcaagcg ccgcctggac
      301 gctgtcaccg gaggcgacga cgacgacaat ggcggtgggg atcgccacac gcagcccctg
      361 gagcatcagg gcgatgaagt gcatgacctc aatggcccgc atattcgccc gatcggcgaa
      421 cctgtccgcc tggtgggcga agaagacgtt gatggtgcgc acgaagatgg tgagggcctg
      481 gccggcgacg gccagcggga ccgccacagc gatggcctcc ccctggctct gccctccagc
      541 aataacgatg accgtggaga cggtggaggc gagggcggca tcgggggcca tggcggcgcc
      601 gacattcatc caccccaggc tcaccagctc cagggagccg ccgatcataa taccggtggt
      661 cgggtcgccc agggcgaggc cggtgagggt gcaggcaaca ataggacggt agaacatgcg
      721 ctcgtccaga acagcatcgc aaccggccag gaaggccaca agcgtcacga gaatgatctg
      781 aaccgcattg atatcatgca tgaggctgct ttctctgcgg atttcggaga atctggtgga
      841 agaggacggg ggagggcgca gggacgagcc cgggcaccgg cgtcgtcggc gctcctcctg
      901 aggcaccggc gtcgtcggca ctcctcctga ggcgccggcg atgccgctcg gctgcgcggc
      961 agacgaccgc ggcgcgaccc gccgcgcggc cgagggtcgc ctcaggagat gaagcccttg
     1021 gacctcagcg cctccatgag atccgagcgg cccgtggagg ggacctgctg gatgtactgg
     1081 gcgatcccgc gcttgtcgat ctcctggaag gccttggcgt cctcgtcgga gatgtagacg
     1141 gcctgggaca gggccttggt gccctgcttg aaggtcatgc cgccgacatt gacctctttg
     1201 gcctcgacgc ccaggtcgag cagccggacg atgtccgccg gggtctccac cacgatgacg
     1261 gccttgaggg aggcgtactt cgggttcttg tagacgcggg cggccttctc cacccccagg
     1321 acgtgcacct tgaccttgcc gccgccggtc tggagcatga gcgtcttgcg cagctcgtcg
     1381 ttggcggcgc cgtcggacac cgcgaggatc gcctcggccc cgaggcttcc cgcccagttg
     1441 ttggccacct ggccgtgaac cagtcgtgag tcaatgcgca ggagcttgat gtccatcaga
     1501 gctcgtctcc ttcgtcgtcg gaatcggtgt tggtgggggt gaagatctcg gagaggacct
     1561 tgacgccgcc ggagccggcg gtccgggccg tctcgaccag ctcgggcagg gtcccgccgg
     1621 tcaggcggcg gccgaggacc tcgatgagca tgggcaggtt gacgccggtg acgacgtcgg
     1681 catcctcacg ctcagcggcg aagcgcgccg ccgcgttgta ggggctgccc ccgagcaggt
     1741 ccacgagcac caggtactgg tcgctcgggg acttctcgac ggcggcggcg tacttggcga
     1801 gcagatcgtc cgggccctcc gaggactcga aggtgacagc gacaagatct tcctgggggc
     1861 ccgcaatcat ggcggacgag gcgatcagcc cctccgccag gtgcccgtgg gcagcgacga
     1921 tcacagcaac catgctcact ccttcgtgaa tcgcgcaggt ccccgcccgg gttgggcagg
     1981 gacgtcaaca agcagaacaa acgttacctg catcacacag atacggcagg tcgagcgtcc
     2041 gatattcgac caccaaagac cgatttgtgt cctatctcat agattaggtg tagtgtggac
     2101 gggaggctac ccatgcaccc gcccgcacgc gcccaacagc gggctgccgc cgcccgccgt
     2161 gcgccgccgc acgcctccgc ccgccgtgca aggggcaaca ctccaccgtc agcctgctga
     2221 caagggcccc gcggccaccg gacactgtgc ccatgagcac gccacccacg agcacgcgga
     2281 gcacaccgcg cacacagagc acgcccgacc ccgcgcgccg cacgcgcctc ctcccacggc
     2341 gcagcgccct gaggtccttc tcggcgctcg cggccctggc gtccacgggc gcgctcaccg
     2401 gatgcggctc gacccccgac aaggaccgcg acgacgcgct ggccaagatc gagtggctgc
     2461 cctcggaggt cgacaccgag tccgtcagcc tggaccagca gcgcgcgacc accgcggtga
     2521 ccgcctgcaa cgccgtcggc gccaccatgc tctccaccct gctgcgccag gcgacaggct
     2581 ccaacgcgct gtcctgcccc gtggggatca ccttcatcct ggccctcctg tacgccgggg
     2641 ccgagagcgt cggtgagggc gtcaacgccg cccttggcgt caaggccgac gcccaggccc
     2701 agtcccgcga ctccacctgg agcgccgtcc ggcagaccct ccagcgcttc gacgtcgccg
     2761 acgtccagca gctgcgagac ttcgaccccg ggaccatccc ggaatcaccg ctgatccacg
     2821 tcgccaacaa cattatgatc gttgacgaga agaccgtggt ccgccaggag tacctcgaca
     2881 acgccaagcg ctggtacgac tccgagatcg gccgcatccg caaccccgac gccagggcgg
     2941 ccctcgatgc ctgggccgcc ctccacaccg gcggcctcat caaggagtcc ggcatcgaca
     3001 tcacgcccga cacgcgcctg gtgctgcaga acgcactgct cttcgccgcc cgctgggccg
     3061 cccccttcaa ggccgaggag acggagaagg gcgcacagtt cacgctcgcc gacggctcct
     3121 catccaccgc cgacctcatg accgacacgg gcgtctaccc gctggtcagc gggaaggggt
     3181 ggcgcgccct gcgcctgcac tacacggccg gatcggactc gccgtcgtcg tcgagcggga
     3241 ctgactccga ggcggtcgcg cccggctccg gctcgccgtc gtcgagcacg gcggggtcga
     3301 gcgcgcccga ccccgggccc ggctccgcct ccagcaacct ggccatggac gtgatcctgc
     3361 ccgacaacgt cgtctccccc gccgacctgc cggcgagcac ctggggcgag gcgacggcgg
     3421 ccctcacggc ggccaccgcc gagcagcagg tcgccctcaa gctgcccaag ctcgacctgg
     3481 cctccggggt catggacctc ttccccgtcc tgacagccat gggcgtcgat ctgggatcgc
     3541 tggaccacat cgccgagggc atcgacgcca cccaggccgc ccagcaggtg cgcctgatcg
     3601 ttgacgagga gggcaccgtc gccgcggccc tcaccgagat cgggatcgag acatccgcag
     3661 tcgatgagtc ggacgccgtc gagttcaccg tcgaccaccc ctacgtcctg cggatcgtgg
     3721 acctcgcctc gggggtggcc attatcgagg cggccatcct caaccccgcc ggctgaggag
     3781 cgcgggcggg ctcccggttg tcccggggca ccgggacaac cgggagcccg cccggaccgt
     3841 cacttgccgg agtagcggta cacgttcgtc tcgcgcagct cgaagccgca gcggcggtac
     3901 agacggttcg cggcctcgcg ggaggggcgg gaggtcaggt cgaccgtgcg ggcgccgagc
     3961 cgaccggcgt gggcgacggc cgcctcgacg agcgcccgcc cagcgccctg gccgcgggtc
     4021 gcggaatcga cgacgacgtc ctccacccag gcgcgcagcc ccgtggggat cgagaatgtc
     4081 gccagggtca gcatgcccag gatcgggcgg gcgccgtccg cggcgggctc gtcggggcgg
     4141 aagacgaaca ggtagacgcc ctcctgcgcc acgaaggcct cgcactgctc ggcggtcagc
     4201 gccggcgctg agcgtgagag ctgagggatg aggcgctcca tcgcctcgat gagctcgggg
     4261 gtggactcgg cgatgatctc aacggtcatg ggctctcctc gtgtttgcgt tctgctcggt
     4321 tgtgcgcagt ggcgggccgc gggcgcgtga gcctcggcct gcggggagcc taccggcccc
     4381 ggcgccccgc acgggccggg catgcgggcg gcccggcatg cgggcgggcg gcctgggccg
     4441 gcgccatctg cgctcccccg cgtcgagata gacattctcg gacgatgtcg acggtgtcac
     4501 cgtctatctc gtccgagaat gtctatctcg acgcatgctt ctcgtatgag cagtgatctt
     4561 tccggcgccg tcccgaccgg ggccgcggcg gcgtgcgacg ccattggtgc gcgcatgctc
     4621 gccgggcgcc tccacgaggg cggtgccggc agcacgatca gcgagaacag cgaggccggg
     4681 cgtggcagtc atgatggtgc tgcagaccac cgcaatgtgc tggcctgccc ggtcgggctc
     4741 gccctggccc tggccgtcct gcgcgccgga gcagccgacg ccggcaccga cgccgcactc
     4801 ggaatcgaca gcgcgcccgg caccgacgcc gcgcccgcgc tcgtggccga cggtgcgccc
     4861 cgggtcggcg tcggcacccc cgactccacc ggcccgcgcg cacccgggga ctccgcctcc
     4921 ccgctccccc gcgacctcgt ctggtccgcc gtccagcgcg ctctccggcg cttcgacgtc
     4981 gccggccccg agcagctgcg gagcttcaac cccgacgcca taccggagac gccgctggtc
     5041 cacatcgcca ataacatcct ggtcgtcgga gagcacgtag tccgccagga ctacctcgag
     5101 gccgccaagc actggtacga cgccgagatc agcagaaccc cgctcgcgga ggccaaaacc
     5161 gccctcgacg cctgggccga cctgcacacc ggcggcctca tcaagcagtc agccatcgtc
     5221 ctcaggcccg acacggtcct cgtgctgcag aacgccctcc tgttcgccgc ccgctgggag
     5281 cgccgcttca caaaggcatc gaccatcgag aagcagccgt tcacgcgagc cgacggatcc
     5341 acctcgcggg ccgacctcat gaccagcacg cgcccctaca ccctcgtcgc cggcccgggg
     5401 tggcgcgctc tacgcctgcc ctacaacggt ggcggagcga ccggggggcc gacgctcgcc
     5461 atggatgtca tcctgcccaa cagggtcatc tcccccgcca acctgccggc gagcacctgg
     5521 ggcgaggcga cccggctcct caccgccgcc caggcggagg accgcgccac cagggtgcgc
     5581 ctccggctcc cccggctcga cctgtcctca cagcccaccg acctcaccgg cgtcgtcgag
     5641 tccctcggcg tgcccctggg cagtcaggac catatcgggc cgaacgtgtc cgtgagccag
     5701 gtcgtccagc aggtcaggct caccgtcgcc gaggagggga cagtggccgc cgccctgacc
     5761 gagatcaccg ctcgttctgg ggcgctcgcg ggctgggagg acgacttcgt cgtcgaccat
     5821 ccctacgtcc tgcggatcgc ggaccaggcc tccggcatcg cactcatcga ggccgccgtc
     5881 ctcgaccccg ccgccggcac gcggccccgg tgcccggtgc tggtcgaggg cgcgagcagg
     5941 ttgagggcgc ggttcactcg gaggaggcga ggaccgagtc gatgagggag gccaccgacg
     6001 tcgtcgtgcg ctcgcagacg gccaggacct cgggcggcga gccgttcatg gcgacggcgt
     6061 ggtcggcggt ctcgtgcatg gagatgtcgt tccacgagtc gccaacgctc caggtctcga
     6121 tgcgctcgcc ccggcagggg ccgtcgtcgg cggcgagacg ctcgaccagc acggtcaggc
     6181 ccgcgccctt ggaggagccg gcggggacaa tgtcgaggaa gttctggttg tggaagccca
     6241 cggccacgtc gccccaacgg cgtgcgacct cggcctgcat gtgcgccatg agcgccgggt
     6301 cggcgatgcg cagcgggacg ccgacgacgg tgcgtccggc caggtcggcg cgggaggccc
     6361 tggagaacag cgtgagcagg gccgtgtcgg agccgatcga gtcgtagagc tggaggtcgc
     6421 cctcgagcgt ggtggcgaag acggtgacgc cggtctcgcc ctcaagcagg tcgaggacct
     6481 cctcggccag gccgtcgggc agggtccggg cctccaggac gtcgtagccg ccgtcggcca
     6541 gggcggcacc ggtgtagagc acggagtagt cgaaggccag gtcggagccg ctcagagccg
     6601 agtgcagggc ggccaccgag cgcccggtgt tgggcacgag gaggttgccg gcgtcgcgcc
     6661 agcgcgtcat ggcgtccagg tcgtcctggg agattgccgc gttgaacagg agcgtgccat
     6721 cgatgtcggt ggacaggagc ttgcgcatcg ccccagccta cggggcaggg cgggttccgg
     6781 ggcgccgtcg gaccgatctc ggcgcggaac cggaccgatc tcggcgaagg ggcgccgagg
     6841 gcgggcggaa ggcgcgagcc ggcgggggac agcgcgagcc ggcggaggac aggaccggga
     6901 gcagatcgtc tcgagcgagc agttgcgcat ggagcactct gtagtgtaga gtcctctgtg
     6961 taccccaaga gagagcggaa ctgatgtccc tgaactttca cacccccgtc cggctgacag
     7021 acgtcagccg cgacttcgga cccgtcaaag ccctgtcgaa cgtgaccctg tcgatcccgg
     7081 cgggcggaac tgtcggactg ctgggcccta acggctcggg caagacgacc atgctgagtc
     7141 tgatcgccgg cctgagggag ccgacctcgg gaaccgtgga gctgttcgga gccgatcccc
     7201 gggacagggc ctcgcgcgaa aggctcggcg tcaccccgca gcagtccggg atcgtcaagg
     7261 agatgaaggt cctcagcatg acgcgattca ttgccggcca ctacgcggac cacgaggacg
     7321 cggagaccct cctggagaag ttcgggatcg gccagctggc cggcaagcgc attggcggcc
     7381 tgtccggcgg ccagcagcgc ctgctgtcgg tggccctcgc cttcgcgggc agaccccgcc
     7441 tggtcctact ggacgagccc tcgactggac tcgacacgat ggcccgcaat catttgtggg
     7501 acgcgatccg tcggggagcg cgaagcggaa tcacgatcct gctgaccagc cactacctcg
     7561 aggaggttca ggagctgtcc gatcggatta tcatcatccg agagggcaga atcgttgccg
     7621 acggctcaac ggagaagatc attcgcaacg ccgcctccac cattgtccgg gtgacgaccg
     7681 gcgatgatcg ggccctgtcg cttcccggag tcaccgcggc gcaccgcaag ggcgctgttg
     7741 tggagctcag cgtcgccaat cccagtaccg tcctgaagtc gctggggcgg gcgggcatcg
     7801 agtactccga cattgacatt attaagccga ccctggaaga cgccttcact cacctggccg
     7861 tcgaggagca aacatcatga caaccgcccg gatccgcccc gaagtcagta atattctcgt
     7921 gcccgactca agactcgctt gggaatggac ccggttcgag atggcctctt ggctgcgcga
     7981 accagccgcc gtcgtgctga acatggccta tcccctgatc atgctgggct tcttcctcgt
     8041 ctcgaccgac atccgtacag actccgcagc ggctatatcc ctactgggtt acctcagtct
     8101 ggtcggcgta ctcatggtct gcctcaactt cccggccaac ggaatcccgg aggcgcgcga
     8161 gtcggacttc tacgccttct cccggacgct gcccatcggc gccgccccac gccttatcgc
     8221 ctggacagcg gcccctattg catgcggcct catcagcgcc gcatcgacat tcattatcgc
     8281 caccctcgtc agcgcagccg agccgtcagt gatggacttc gctatcatca taggcgtctc
     8341 gctggtcctg gcggtgccaa tcacccttct gggtctcgcc ctcggcttca tcctgcccaa
     8401 gaagacctca ctggccgtca gtctcaccat cgccttcagc atgattctct tcggcggaat
     8461 cagcggcatt cccctgccaa gcatcgtcga gactatctcg cacgcacttc cctccggcgc
     8521 cgccggccat attatcgcct cccatctcaa cgcaagcgat ttcgactggc gcaacatcgt
     8581 cgtcctgatc gcctgggccg tcatcggcat ccttgcagta ttccttctct accgccgcga
     8641 cgagggacgc aggttccgct gacctcccat tcattatacg ccttgcccgt tatccagtcc
     8701 gaaggaggtg acaatgcaga cgcccactac tcccgacttc accatcgagt catttgaggt
     8761 cggagccgag aaggaactca gtaccgcacc agctgcagtg tgctgctcat cgattctgtg
     8821 ctgctgctgc taacaatcga cggcgggatg gggcggcttc ataggcttac cttgatgacg
     8881 ctccatcccc gccgcccaca aaggttagcg acaggacact tgctgttcac agaactcagt
     8941 agaaagtgcc atcacatgaa ttccattccg cccaatccaa tgatccagcc gtggatcaca
     9001 gccgccaccg aagacaatac ggttgtcatc cggcacgccg accgagcggt cgtcttcact
     9061 ggcccaggcg ctaaagccct catgcccgaa ctaattgcca agctcgatgg cacttcacaa
     9121 gttgacgcca tcatcaactc ctttccggca gagaagcagg cggcaatcag ttctgctatc
     9181 gatcttcttg cgcatcataa tctgctcatc gaaggcaccg cactgaccca cacaaaagac
     9241 acgccagctc ccggactgcg gaacgcagca tctttagcag aacttctttc acccgcaatc
     9301 actatagacg aaatcgcgtc acggctgagc gccacacatc ttcacatctt aactgacttg
     9361 tctaacatca gtcatttgaa gaacattctc gtggaatcag gatttgggtt tgtcgagacg
     9421 ttcccactgt ccgcggtcac cgaagtcgag cgctcgctga cacagaactc cgtcgtggtg
     9481 gttgcgccaa aactgagttc ggcccgcgaa ctgagacaga tgaatgacat agccctcgag
     9541 attggatgcc gctggaccca catactgcct tacgatggtt cctacgccat tgtaggaccg
     9601 ctttacattc caggagaaac aggatgctac cgctgccttc agttacggcg ccggtcgaca
     9661 atcgaagcag ccgatcagca gcgcattgtg gacgacgacc cggacagcat tctgcccact
     9721 cccctcgacg aatggactag ccccggacaa gaagtcgccc tatggggact gttcgcccat
     9781 cttctatcca tcgagtgcct tcgcctgtat tgggcacctg ctccacttgc cggccatatt
     9841 cacacaatgg agtggaaggg caataccgtg aacactgtgc gccatcgtct cttccgggtt
     9901 ccccgctgcc cctcctgcgg cccaacagat ttgggcgtgc cacagccttg gtttgaagca
     9961 cccgctaccg cggcgaagaa gaattagcgg aagccacatc atgattaata ctgctcagaa
    10021 gaccccccga ttttccgaac ggtggaatga cagaactgca tcgacggaga gtctgctgca
    10081 tctcggctcc gaacacttcg gagtggcgcc cattaagttc gagatcaccc acagtagcaa
    10141 cgaagtcaga agtcactata tcggcgtccg atcagcggca gcagacgaga tcattggcac
    10201 gcccgtcaat cattccaatg gtggcggctc attcagcaga gaacaagccc gtatcgcggg
    10261 aatcgcggag accgtcgaac gatattcagc tgcttatatt cctcgcaccg ggctgagaac
    10321 ctgctcctac aacaatttga atggcccggc cctgcatccg tccgatttcg ctctttttgc
    10381 acctcatcag tacgagcagc ccgcctttcc atacatacca ttcaccgcag agacagtcac
    10441 cacctggacg cagggcctga gcctacgaac tggccttccg acgtatgttc ctgcgcaact
    10501 cgtctacctg aacaggcacc tcgaccccga ctcccgcatt ggttatgcta ccagtaacgg
    10561 actggcttgc ggccccgact acacggaagc tgcaatatcc gccctcttcg agtgcgcaga
    10621 gcgcgacgct gtcatgatca cctggaacgc aggtctagca atgcctcgca tcgacctcaa
    10681 ctctaaccta tgggtccgta aaatcatccg gcgtcacttc aaaccaacct ggatgaactt
    10741 tgcggccttg gatctgaccc ccataaacgg aattccgaca agtttggcag tagtttggag
    10801 caataaccct gaaacacagc tcctctctgt cggcgcggcc tcccgctcta ctcttgccga
    10861 ggcatgcgtg gaggcccttc ttgaggcctt tcattgcact gcttattgtc gctcactcat
    10921 tcgagataat ggttcaatcg atacctcgga caatctcgac aagaaagtcg tctcgctcga
    10981 ggatcatgtt cgtttctatg gtagcgacga gcacgcaaaa ctggcggagt tcctgctcgg
    11041 gtcatcgcaa caaattgatc ttcagagcac gccgaatctg gaccactcca gcccgcggca
    11101 actcttggag gaactcgtcc gcactcttga cggtgacatt gattgcacga ttgtcgacgc
    11161 gacatctccg gatcttcagg aactcgatct cgccgtggtc aaggcggtct gtccacagtt
    11221 cattcccctt ggagtggggt ggcgagatag atatatagga ggagaccgca tactcgacgt
    11281 acctcaaaaa atcggtctgt cagatcatca acttgcctac agtgaactca cgccatatcc
    11341 gcatccattc ccgtgagccg tggggaggaa ccgtgaccac gccaaacaca ctcgaaatca
    11401 ttcaacctat cgaacccggg cttttcgatc ccgcagaaaa tttcatagaa gcgagtaaac
    11461 ttcatcggca tctccttgag gccgaggtac caggaatccg agaactcaca cgatcacccg
    11521 cgttgcttga tgccactggg agggctacaa acccttaccc tcagcgcacc ccgatcctgc
    11581 ttcccgaccc tgcgtcattc cctcaagaag catccctctc tgacgtgctg caggaacgtc
    11641 gctctcctcg cggattctca tcatcaccag cgctctcact ggataagatc ggatggttgt
    11701 gctgggccac agacggtaat accggcgaga tcgctccgaa tcgttacgga agaactgcac
    11761 ccagtggagg cgccctgtat cctcgagatc tttacgtcac cacgatcgcg ggagacgtcg
    11821 aagccggact ctaccattat aatccttatt tgcaccacct tgaatttgta aattcaacga
    11881 ccccgcacga tgttgccggc acaacagcac agccagaagc actcgcccag gcatctgccg
    11941 tcctgcttct tatggcgtca ttttggcgca accggatgaa atataaccaa cgcggagtcc
    12001 gctttgcgct gacagagtcc gggcatgtcg ctcagaatgc cttactggcc gccgtggcct
    12061 taggactctc agccctccca ataggaggct actttgacga agagcttaac acgatgcttg
    12121 gcgcggacgg acttcacgaa gaagtcctgt atgcaatttt ccttggtagt ccactatctt
    12181 agatctggcc gtgacctcct taaaggagtc gcagcatgat cgaattcatg tccggaagcc
    12241 tcatatttct ggggtggtgg gcaacgtgga ccacatatat taagtacctt cgacgaacat
    12301 ctcaattaca taggttccat tccggcatct atgacttgtg cacacttgcc tacgctcttt
    12361 tagctctcat cctgagcgcc gctcatatca caccattcac actgcctcaa ctccgatcag
    12421 gtccaatcga ctatcttata gccgcggcct ccgggatcgc actctggagt cttcaacgaa
    12481 tctatctgtg gcatgcgcga catcggacga atagtgactg cgctctgggc cactaccctg
    12541 ttcggcggcc gtacctccta ccgctgaccg ccgccaccga agagatactt tttcgaggct
    12601 gcctgctgta cggtctgata ttcctgggcg taccgcccgc aggagcgatt ctggcaacgg
    12661 gcatgctatt cggttcactg catgcttttc agtacggcct gtacggagtc gtgctgcaca
    12721 ctgtcaccgg catcgcgttt ggtatactgg ccgtgcgctt cggcctgggc gcagccgtcg
    12781 ttgcgcatgt tatcttcaac gcgatggtgc ttctcactgc gagaggaccg gcccggtcgc
    12841 ccacgacgga gcgggccggg cacgggaggc cagcgggcga ctaggccgcc ccgaggtttt
    12901 cgactaggag ggtcacgcaa tggcattaga tcaccgggac agtgcggcgg aggagcttcg
    12961 gaggatcgag gactaccgaa agagctttcg tcagagcacc cgtttcgatg accggttcgc
    13021 ctgccgtatg ctggcggtaa catacttgct gggattcggg ggccagtatc tcgcgatgat
    13081 cctgttcccg tccttcgccg acaaggcagg aaccgtgctc atgtcggtgg gatcatgcgc
    13141 cgtgttcgtc gtcttcaggc acagcctccg acagcacgcg ggcatcagcg ggagagccat
    13201 ccggaaatca atttacttcg gatccgcctg gctcgtcggt atggcggtgg tgtcggctgt
    13261 aatcgctctt attgtcgccc ggctccccgg cctcgacgtc attggagtca cgcggatcgt
    13321 ttacgcggtc gcatgcgttc taacgggatt catgtacata atcggcggca tattatttca
    13381 tgaccgttca gagctgtccc tgggcggctg gctcattgtg gtgagcgttt tcagcgccct
    13441 cctgggaatg cctctcatgc tcctgtcgat cgccgtcctg tcagctctgg gcttcctcgg
    13501 tctggcgttc gtccgatccc gcgccgatca gcgggcggca tcatgactca gaaacagatc
    13561 gacgatctca ttcacgcccc gaccaggctg agaatcatgg ccgccctcgt agaactgggg
    13621 cctgacagtg agatcacgtt cccaagactg cagactctgc tgaacatgac cccgggcaac
    13681 ctgtccagcc atttgaagcg cctggagggc gcggactacc tggccatgtc gaggagcttc
    13741 accccccggg gcgtggccaa gaccactgta cgggtgacgg acacgggcat tgcggccttc
    13801 gacgcgtacg tcgccagcct caagagcatt attggtgcgc cgctggaggc gtgacccgcc
    13861 ccgggagatc accggaaccg atctcggtgc ggaagtggac cgatcccggc gaaggggcgc
    13921 ggcgggacgc ggggcgagag cgcgccccgg cgcgctcagg caggcgggac gttgcgctcg
    13981 agctcggcga tccaggcggc tgcgccggcg tccgagggca tgcgccagtc gccgcgcggg
    14041 gacagcgagc cgcccgcgac caccttcggc ccgttgggca gcgtggagcg cttgaactgg
    14101 ttggagaaga accggcggag gaacagcagc tcccacctcc tgatggccgc caggtcgtag
    14161 gcgacccgct cctcctccgg cagcccgacc ggccaccggc cctcacccgc gtccgcccag
    14221 gccttctccg ccaggaaggc gatgcggctc ggccgggacc cgcggcgcag cacgtgccac
    14281 agggtgaagt cctgcagggc gtaggggccg atcctggcct gggtggactg gatgggctcg
    14341 ccgtcgtcgg cgggcaccag ctcggggctg atctcggtgc cgaggacggc cagcagcacc
    14401 cgcccgacgt cgtcggagaa gatccgctcg gacaccaccc agcggatgag gtgctggatg
    14461 agggtcttgg ggatgccggc attgaccccg tagtgggcca tctggtcgcc caccccgaag
    14521 gtgcaccagc ccagggccag ctcggacagg tcgccggtgc ccagcacgat gccgccgcgc
    14581 cggcccgcga tgcggaacag gaagtcggta cgcagcccgg cctggacgtt ctcgaaggtg
    14641 acgtcgtaga cctcgcgccc gcgctcgccg cgcccgtagg ggtggtccat ggcggcgagc
    14701 atctgctcgg cggcgggacg gatgtcgagc tcctcgacgt ggcagccgag cgagcgggcc
    14761 agggcgagcg cgttccgcct ggtctcggcg ctcgtggcga agccgggcat ggtgatggcg
    14821 tggacgtgct cgcggccaag gccgaggcgg tccacggcgc gggcggccac aatgagcgcg
    14881 tgggtggagt ccagcccgcc gctgacgccg ataacgatcc tgggcagccc gatcgcgcgc
    14941 agccgctgga ccagggcggc gacctggatg ctgtaggcct cgtagcagtc ctgggcgagg
    15001 cgggcagggt cgtcggggac gaaggggaag cggtccacgg cgcggcgtag gccgatgtcg
    15061 gtgcgcggcg cccgcagcgt ccgccgcccg atgcgcacgg tgcggaagcg accgggcccg
    15121 acggcgtccg cagcgccggg cgcgggggcg ccgtcgggcc cggggtgccc ccgcccgggg
    15181 cgccctggcc cgccgagggc gagcgccgca cggttgtcgt cgaaggagcc ctggcgcagc
    15241 cgctcggcgc gcagcccctc gatatcgacg tcgatgaccg tggcgcgcgg cccgtcgggg
    15301 aagcgctcgg tctcccccag gaggtcgccg ttctcataga tgaaggtctg accgtcccag
    15361 gccaggtccg tggacgactc gccctgcccg gcggccgcga acacgtaggc ggccaggccc
    15421 cgcgagctgg aggcgcgcgc caggagcttg cggtcctcgg cccggcccac ggtgatgggc
    15481 gagccggaga ggttgaccag cacggtcgcc ccagccaggg ccgccagcga cgacggcggc
    15541 acgggcaccc acatgtcctc gcagacctcc acgtggaagg tcaggcccgg cacgtcggcg
    15601 acctcgaaga gcaggttcgg gccgaagggc acgacggcgc cgccctcccg gttcccgacg
    15661 gcgggggtcg cccctgcgcc gtcgcggtgc ccgacggcgc cgccctcccc tgcgccgtcg
    15721 cggacccccg gcagggagat ccgccgggcc gccgcgctgc gcccgtcggc gccgtcggcg
    15781 aagtgccgct tctcgtagaa ctcgcggtag gtgggcaggt aggacttcgg gacgacgccg
    15841 cgcacggccc cgccctggat gacgacagca cagttgtaca ggcggttgcc ctcccgcagg
    15901 ggcgcgccga cgacgatcgc cggcaggagc ccggcggagg ccgcgcggat ggtctcgatg
    15961 gcggcgagga cctcgtcgag cagcacgtcg ccgagcagca ggtcgtcgat ggagtagccg
    16021 gtcaggctga gctcggggaa ggcggccagg cacacgccgt cgtcggacag ggtgcgggcc
    16081 tgctcaatga tcgccgtcgc gttggcggcg gggttcgcca gcgcgacggg cagggtgacg
    16141 gcggccacgc gcgcgaagcc ctggtcgtag gcggagcgga actcgatggc cggccggccg
    16201 gtggcggggg gcggcgtggg tgcgtcctgg tgcatgtgac gatcctccca cggacgtcgg
    16261 ggcggggcgc ggggcgggct gcgggcagcc ggagggcccc ccggggcggc tccggggccc
    16321 cggaggggcc ctcagaaccc ccgacgttac cgattcgtta ccttcggaga ggaatcgaga
    16381 tcatttcgtt atcatgggcc cgcggaatct cgcggaatcc ccgtggggcg ggattggatt
    16441 ttcgagccgg gaccccctat agttttcctc gtcggaacgc ggacgacacg aggggatcag
    16501 ggaccctgtt gactgtcgtc gcgttcgggg atgtcgcgat tcagggaccg cgcccccgag
    16561 cccgacacga ggccccgcac cgcaaggtgt cggggcctcc ctctgttctc cggcaggtca
    16621 tgatcgcaac acctgccgga gaaccgccgg gggacgtcgc gatcagtcga gccccggctc
    16681 gggatcgctt cgcttccgcg ccgagaccgg ttcacccgcg ggcatcggcg tcgatccgcc
    16741 accgctcccg cagcccgtcc acgaacatgc ggacctccgg ctccatcgag gtggccaggc
    16801 actgatccgc ggcgctgtcc ggcgtcgtcg agcacagcca ctggatctgg agcccgtcgc
    16861 tgagggccac gaccgaccgg gcgatcatcc gcgacggagc ctccggacgc acggtgcccg
    16921 tctccttccc ccgctccagc gcctcctcga tcatcctcac cgagcccgcc agatgactgg
    16981 cgaaccaccg gtgagccgga tgctcggcgt cgagcacgga caccgccgtc gccgcgtaga
    17041 tcgccacgag gtcccggtga gccgagttgt gcgcgaccag cgtcacgaag gcgtcgagca
    17101 gctcccacgg gtcctcgatc gcgccaccac ccatcacgcc gacgaagtcg tcctggtccc
    17161 gccgcgccag cacccgggcg aagagcgcct ccttggagga gaagtggtgc agcagccccg
    17221 ccttcgagat gtccgacgcc gtcgcgatat cggccaggga cgtgccggcg tatccgtgcg
    17281 ccccgaacag cgcgatggcc tcgttgagga tccgctcgcg cttgtcctcg ccgccggccc
    17341 tggggcggcc cggcttgcgc cgatcggcct cctcgatctc ggagggatag tcaccggggg
    17401 aggcactgtc aatactgttc ataccagcat tgtggcaccg ggtcccgccc gcgcccggca
    17461 ggcgcgtccc aatatctcga actgatctca gcgcggaact gatgcgcgcg ggcccggcgg
    17521 ccgcgcgacc attcttcgac ggcgaggctc ggcttgtccg cagttcgggc gccgccccgg
    17581 ggacggcccg caactggtgc gcacgcgctc cttgcgcgcc ggtacgcggg gcggccgcgg
    17641 caggccggca cgcattcgcc catcgcataa caccgcgccc cctcccggtg cagcagcagt
    17701 ctatgaggat tatccatggg acttatgcga atatgatttc gaggatgacc gcgagagctt
    17761 cgggttgtcg ccagtccagg tcggcctccc gggggtcccg gagagccgat ggaggcccgg
    17821 cggcgggcgc cccgagtccc cttgaaccga tctcgagccg gaagcggacc gatctcgacg
    17881 cggagtacga ccgatctcgg cgaacgggcg gcggccgccg ccggtggacg gggagggtgc
    17941 cggcgcgggc acctacagcg tcccgaacga gagcacctcc acggccaccc acacgcagaa
    18001 gtcagccggc tgctgaccct gaggcggagg agggcatcat tcctttgccg acgctcaacc
    18061 cgccacaagc agcaacgcac ccagcgtaag catgagcgaa gcggctacat gccgctcact
    18121 actcaacctg gatatcactg ggtctcacca cgtaccccaa agagcgcaga aaaggccccg
    18181 gcccagcgcg caccataatg agaggcctgg ccgagggccg attgattggg tttgcagcat
    18241 cggactgggg cgaaagagac cgatgccgcc atttatgtgt tctgcataat atccgggacc
    18301 gagtcgcacg agtcgcacgt ccacccaccc tgcggagcgc ctggcctcga cgcgggcccg
    18361 gcccgcctgc cccacttccc cacgcagaag cccggccggg ggcggcaggt gaacgcgcct
    18421 gccgcccccg gcccgccagc cgtcggtgca cgccgtcccg gctcaggccg gcctcagagc
    18481 ccgccgcccc gcccggctca cacggcgctg gttgcggacg gcgcccaggc ctcgccgcgg
    18541 gcggtcaggg cgagcccggc gagcacgccg tcggggctga cgtccaccac gacctcctgg
    18601 ccgtccagga cctccccggc caggatcatg cgggccagct cgtcgccgat ctcgcgctgg
    18661 accaggcggc gcagcggccg cgccccgtag gcggggtcgt agccctcgtc ggcgagccag
    18721 gcgcgggcgg cgtcggtgac cgacagggtg agccggtggc ccgccaggcg ctcctgcatc
    18781 ttggccagct ggatctcgac gatccggccc agctcctcct tgctcagcgg gtcgaagacg
    18841 agggtgtcgt cgagccggtt gaggaactcg ggcttgaagg aggcgcgcac ctgcgccatg
    18901 acctccttgc gcttctcctc ggggctcagc agcgggtcga tgaggaactg gctgccgagg
    18961 ttggaggtga gcacgaggat gacgttgcgg aagtccaccg tgcgcccctg gccgtcggtc
    19021 aggcggccgt cgtcgagcac ctgcagcagg atgtcgaaga cctccgggtg ggccttctcg
    19081 atctcgtcga gcagcaccac cgagtagggg cggcgccgca cggcctcggt gagctggccg
    19141 ccctcctcgt agccgacgta cccggggggc gcgcccacga gccgggccac cgagtgcttc
    19201 tcggagtact cggacatgtc gatgcgcacc atggcgcgct cgtcgtcgaa caggaagtcg
    19261 gccagcgcct tggccagctc ggtcttgccg acgccggtgg ggccgaggaa gaggaaggag
    19321 ccggtggggc ggtcggggtc ggacaccccg gcgcgcgagc ggcgcacggc gtcggcgacg
    19381 gcggtcacgg ccgccttctg cccgatgaga cgctcgccga tgacggactc catctccagg
    19441 agcttcctct gctcgccggc catgagcttg cccacgggga tcccggtcca ggaggagatg
    19501 acctcggcga tctcggtcgg gccgaccttc tcggcgatca tgggctcggg cgcggtgccg
    19561 ggctcgcgct cgacgccgtc gggcccgacg acggcagcat cggccgccgc ctgagcggcc
    19621 tccatgtcgc ggatctgcgc ctccagggag ggcatctcgc cgtagcgcag gcgcccggcc
    19681 tcctcgaagc ggccctcgcg ctcggccagg tcggccctgg tgcgcaggtc gtcgagggcg
    19741 gcgcgcagct cgccgaccct gttgtggccg gccttctcag cctcccaccg ggcgttgagc
    19801 gcggtcaggc gctcggaggc gtcggccagc tcggcgcgca ggcgctccag gcggtccgcg
    19861 gcgtccgggt cggcggagga gccctcctcc tcgatggagt cggccaggta ggactcctcc
    19921 atgcgcatgc ggtccacccg ccgctggagc tcgtcgatct caacggggct ggagtccagc
    19981 tccatgcgca gacgtgaggc cgcctcgtca atgaggtcga tggccttgtc gggcagctgg
    20041 cggccggtga tgtagcggtc ggacagggag gccgcggcca cgagggcgcc gtcggagatg
    20101 gtgacctggt ggtgggcctc gtacttgggg gcgatgccgc gcaggatggc gacggtgtcg
    20161 gccacggagg gctcaccgac gaagacctgc tggaagcggc gctccagggc ggggtccttc
    20221 tcgacgttct cgcggtactc gtccagcgtg gtggcgccga ccagccgcag ctcgccgcgg
    20281 gcgagcatgg gcttgagcat gttgccggcg tccatggcgc cctcagaccc gcctcccgct
    20341 cccacgacgg tgtgcagctc gtcgatgaag gtgatgacct cgccgtcgga gtccttgatc
    20401 tccttcagga cggccttgag gcgctcctcg aactcgccgc ggtacttggc gcccgcgacc
    20461 atgcccgcca ggtccagggc gatcaggcgc ttgccgcgca gcgactcggg cacgtcgccc
    20521 gccacaatgc gctgggccag cccctcgacg acggcggtct tgccgacgcc gggctcgccg
    20581 atgaggacgg ggttgttctt ggtgcggcgg gacaggacct ggacgacgcg gcggatctcg
    20641 gcgtcgcggc cgatgaccgg gtcgagcttg ccctcccggg cggcctcggt caggtcggtg
    20701 ccgtacttct ccagggactt gtaggtgccc tcggggttgg gcgaggtgac gcgggcgctg
    20761 ccgcggacct tgggcagggc ctcgcgcagc gcggcggcgg tggcgccggc ctcggcgagg
    20821 atgcgcgcgg cggcgtcgga ggacggcttg cccgcggcaa tgccgatgag caggtgctcg
    20881 gtggagatgt actcgtcgcc gaggctcttg gcctcggcgg aggcggcctc gagggcggca
    20941 agcaggccgc gggagggctg gggctggctc accgagctgc cggacgacgt cggaagctgg
    21001 gtgagggcgc gacgggtggc ggcgccgatg gcctggcggg cgccggcgtc ggggttgacg
    21061 gcggcgagca ggccgacggc gacgccgtcc tcctggccga ggagctcggc gagcaggtgg
    21121 agagtgtcga tctgggggtt gccggccgcg gcggcggcct gcatggctcc ggagatggcc
    21181 tcctgggagc gggtggtgta gttcgtgtcc atgtggacct ccttgaagtc gttcagacgg
    21241 cgcaggtcct ggcgggcggg gcggtcgagg gcccgctcct ccggtggtgc cggtggcggt
    21301 gaggtcccgg tccgcgggcc cgcggggatc ctggcgtctc cggccagtgc aacctcgcca
    21361 gagctgagtc tattccgctc agcttactgg caagccgggc gctttctgcg atgagcgcca
    21421 cacgggcccc ttggcgcgcc ccgcaaagac gccggaccct tgcacgcgcc gcccacggag
    21481 gaccggcgca cgcggcgccc ttgacacgga gccgtcgggc acgcggcatg atcgccgcca
    21541 gaaccacgac cgtcgccgac accgagacct ccgccggacg gcgaccggca cggcaccggt
    21601 ggcggcggct gtcggcggcc ccgggggtcg caaccggcgc tgcgcggagg ccgtgcaggc
    21661 tctcgctggc gagtggcggc cccgggggtc gcgaccggcg cgatcgcccc cggcatcgat
    21721 ctgccccgcg ggggggggcg cccggggagg gctgagcggg aagcggacgg actccggcag
    21781 tgggtacttc tgcccaccgc cgcgccagga ccatcgcata cagtgagaag tgttcttcag
    21841 caacgacccc aagcaccggg agacactcat gaagaccttc caccgtgcaa ccgccgtcac
    21901 tgccgcagcg ctcctgtccg catccctggc ggcatgctcc tcgaccagcc ccaggaacga
    21961 ttccagcggc gactccaagg atcaggagag ctcggcccag ccgacagccg tatccgctca
    22021 gccggcgccc gccggatacc agatggtcac cacgtccacg tcgaagatct ccttcgccat
    22081 tcccgataac tggcagatcc tgagcaagga cgccgcccag gacgaccagc gggttcaggc
    22141 tatcgcggac gcgctcggca agagccccga cgaggtccgc ac
//
